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To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ajog.2007.06.030 Byline: Tiffany A. Moore Simas (a), Sybil L. Crawford (b), Matthew J. Solitro (c), Sara C. Frost (a), Bruce A. Meyer (a), Sharon E. Maynard (c) Keywords: angiogenic factors; placental growth factor; preeclampsia; soluble fms-like tyrosine kinase-1 Abstract: The objective of the study was to evaluate angiogenic factors for the prediction of preeclampsia in high-risk women. Author Affiliation: (a) Department of Obstetrics and Gynecology, University of Massachusetts Medical School/UMass Memorial Health Care, Worcester, MA (b) Department of Preventive and Behavioral Medicine, University of Massachusetts Medical School/UMass Memorial Health Care, Worcester, MA (c) Department of Medicine, University of Massachusetts Medical School/UMass Memorial Health Care, Worcester, MA. Article History: Received 13 March 2007; Revised 6 May 2007; Accepted 15 June 2007 Article Note: (footnote) This work was supported in part by the Departments of Medicine and Obstetrics and Gynecology, University of Massachusetts Medical School/UMass Memorial Health Care. S.E.M. is named as a coinventor on a patent filed by Beth Israel Deaconess Medical Center for the use of angiogenesis-related proteins for diagnosis and treatment of preeclampsia., Cite this article as: Moore Simas TA, Crawford SL, Solitro MJ, et al. Angiogenic factors for the prediction of preeclampsia in high-risk women. Am J Obstet Gynecol 2007;197:244.e1-244.e8.

Weight management through the childbearing years is important, yet few women have access to efficacious weight loss programs. Online social network-delivered programs may increase reach and thus impact. The aim of this study was to gauge interest in a Twitter-based weight loss intervention among women of childbearing age and the feasibility of recruitment via Twitter. We recruited English-speaking women aged 18-45 years (N = 63) from Twitter to complete an anonymous online survey including open-ended questions about program advantages and concerns. Forty percent of participants were obese and 83 % were trying to lose weight. Eighty-one percent were interested in a Twitter-delivered weight loss program. Interest was high in all subgroups (62-100 %). Participants (59 %) cited program advantages, including convenience, support/accountability, and privacy. Concerns (59 %) included questions about privacy, support/accountability, engagement, efficacy, and technology barriers. Research is needed to develop and evaluate social media-delivered interventions, and to develop methods for recruiting participants directly from Twitter.

To observe the efficacy of the Extended Colpoperineorrhaphy (ECP), a minimally invasive procedure for symptomatic cure of severe prolapse in acoital women who are not candidates for definitive surgery or pessary.