64 results on '"Suzuki, Shunji"'
Search Results
2. Gonadotropin-releasing hormone antagonist (relugolix) for treatment of uterine adenomyosis with symptomatic endometriosis
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Matsushima, Takashi, Nagashima, Asako, Harigane, Eika, Watanabe, Asako, Shinmura, Hiroki, Ouchi, Nozomi, Kurashina, Ryuhei, Suzuki, Shunji, and Iida, Shinya
- Abstract
Objective: To determine the effects of relugolix administration for uterine adenomyosis on uterine volume and subjective symptoms.Methods: This retrospective observational study included 30 patients with clinical symptoms of endometriosis complicated with uterine adenomyosis who were treated with 40 mg/day of relugolix orally for >16 weeks. The uterine volume was calculated pre- and post-administration, and the volume percentage post-administration. Furthermore, the presence or absence of subjective post-administration symptoms and adverse effects were also examined.Results: The median (interquartile range) long diameter, short diameter, width, and volume of the patients’ uteri pre- and post-administration of relugolix significantly decreased from 9.63 (9.02–11.00) to 8.00 (6.84–9.12) cm, 6.47 (5.58–8.02) to 5.00 (4.26–5.63) cm, 6.91 (5.68–8.46) to 5.49 (4.58–6.00) cm, and 221.04 (146.52–390.26) to 111.90 (71.59–165.84) cm3, respectively (p< 0.001 for all four items). Additionally, the uterus volume post-administration was 48.30% (33.88–62.54%) of that pre-administration. Heavy menstrual bleeding, dysmenorrhea, and chronic pelvic pain occurred in 23 (76.7%), 21 (70.0%), and 13 (43.3%) of the 30 patients, respectively; however, all patients experienced resolution of all symptoms. Nine, three, and one patients had hot flashes, mild arthralgia, and a mild headache, respectively. No cases of persistent irregular or heavy bleeding were observed during treatment.Conclusions: Relugolix contributes to volume reduction and eliminates subjective symptoms of uterine adenomyosis, suggesting that it is an effective treatment for uterine adenomyosis.
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- 2024
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3. Basal metabolic rate in hyperemesis gravidarum: comparison to normal pregnancy and response to treatment
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Chihara, Hiromitsu, Otsubo, Yasuo, Yoneyama, Yoshio, Sawa, Rintaro, Suzuki, Shunji, Power, Gordon G., and Araki, Tsutomu
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Basal metabolism -- Research ,Hyperemesis gravidarum -- Causes of ,Hyperemesis gravidarum -- Health aspects ,Hyperemesis gravidarum -- Prevention ,Pregnant women -- Health aspects ,Pregnant women -- Care and treatment ,Pregnancy -- Health aspects ,Obstetrics -- Research ,Health - Abstract
The authors have investigated resting minute ventillation and oxygen consumption in women with hyperemesis gravidarum measured before and after treatment. Results demonstrate that resting oxygen consumption is lower in patients with hyperemesis gravidarum.
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- 2003
4. Evaluation of High-Risk Human Papillomavirus Testing in Women with Atypical Squamous Cells of Undetermined Significance to Detect Cervical Intraepithelial Neoplasia
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Kawase, Rieko and Suzuki, Shunji
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- 2022
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5. The T-helper 1/T-helper 2 balance in peripheral blood of women with hyperemesis gravidarum
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Yoneyama, Yoshio, Suzuki, Shunji, Sawa, Rintaro, Yoneyama, Koichi, Doi, Daisuke, Otsubo, Yasuo, and Araki, Tsutomu
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Hyperemesis gravidarum -- Physiological aspects ,T cells -- Physiological aspects ,Health - Abstract
Pregnant women with hyperemesis gravidarum have greater blood levels of T-helper 2 cells than other pregnant women. This in turn increased blood levels of estrogen and progesterone. Hyperemesis gravidarum is the medical term for chronic nausea and vomiting that occurs during pregnancy.
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- 2002
6. Curcumin inhibits interleukin 8 production and enhances interleukin 8 receptor expression on the cell surface: impact on human pancreatic carcinoma cell growth by autocrine regulation
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Hidaka, Hideki, Ishiko, Takatoshi, Furuhashi, Takashi, Kamohara, Hidenobu, Suzuki, Shunji, Miyazaki, Masashi, Ikeda, Osamu, Mita, Seiji, Setoguchi, Toshiaki, and Ogawa, Michio
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Interleukin-8 -- Physiological aspects ,Cancer cells -- Physiological aspects ,Pancreatic cancer -- Physiological aspects ,Autocrine mechanisms -- Research ,Health - Published
- 2002
7. Plasma nitric oxide levels and the expression of P-selectin on platelets in preeclampsia
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Yoneyama, Yoshio, Suzuki, Shunji, Sawa, Rintaro, Miura, Atsushi, Doi, Daisuke, Otsubo, Yasuo, and Araki, Tsutomu
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Nitric oxide -- Physiological aspects ,Preeclampsia -- Physiological aspects ,Health - Abstract
Nitric oxide does not suppress platelet activation in pregnant women with preeclampsia as it normally does in healthy women, according to a study of 25 healthy pregnant women and 25 pregnant women with preeclampsia. Preeclampsia is a serious complication of pregnancy caused by abnormalities in blood vessel function. Nitric oxide relaxes blood vessels and also suppresses platelet activation.
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- 2002
8. Morphine promotes simian acquired immunodeficiency syndrome virus replication in monkey peripheral mononuclear cells: induction of CC chemokine receptor 5 expression for virus entry. (Concise Communication)
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Suzuki, Shunji, Chuang, Ann J., Chuang, Linda F., Doi, Roy H., and Chuang, Ronald Y.
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Simian immunodeficiency virus ,Morphine -- Physiological aspects ,Health - Published
- 2002
9. Plasma adenosine levels increase in women with normal pregnancies
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Yoneyama, Yoshio, Suzuki, Shunji, Sawa, Rintaro, Otsubo, Yasuo, Power, Gordon G., and Araki, Tsutomu
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Adenylic acid ,Pregnant women ,Pregnancy ,Adenosine ,Nucleotidases ,Health - Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1067/mob.2000.104832 Byline: Yoshio Yoneyama, Shunji Suzuki, Rintaro Sawa, Yasuo Otsubo, Gordon G. Power, Tsutomu Araki Keywords: Adenosine; platelet activation; 5 I-nucleotidase; pregnancy Abstract: Objective: The aim of this study was to investigate plasma adenosine levels during normal pregnancy and to evaluate the possible roles of platelet activation and 5'-nucleotidase as causes of changes in adenosine levels. Study Design: We measured plasma adenosine levels, the platelet activation markers [beta]-thromboglobulin and platelet factor 4, and 5'-nucleotidase activity, which catalyzes dephosphorylation from adenosine monophosphate to adenosine, in 34 nonpregnant women and 34 women with normal pregnancies in the third trimester. Results: The mean plasma adenosine level in pregnant women was 0.59 [+ or -] 0.08 [mu]mol/L (mean [+ or -] SEM), which was significantly higher than that found in nonpregnant women (0.18 [+ or -] 0.04 [mu]mol/L; P < .01). In pregnant women plasma [beta]-thromboglobulin levels, platelet factor 4 levels, and 5'-nucleotidase activity were significantly higher than in nonpregnant women (P < .05). Conclusion: The increase of plasma adenosine may be attributed at least in part to platelet activation and an increase of 5'-nucleotidase activity during normal pregnancy. This increase may be an endogenous compensatory mechanism that diminishes platelet activation and maintains vessel integrity during normal pregnancy. (Am J Obstet Gynecol 2000;182:1200-3.) Author Affiliation: Tokyo, Japan, and Loma Linda, California From the Department of Obstetrics and Gynecology, Nippon Medical School,.sup.a and the Center for Perinatal Biology, Loma Linda University..sup.b Article History: Received 19 May 1999; Revised 17 September 1999; Accepted 1 December 1999 Article Note: (footnote) [star] Supported by Grants-in-Aid (Nos. 40089175, 00201096, and 30267174) from the Ministry of Education, Science, and Culture and a grant from the Japan Association of Obstetricians and Gynecologists Ogyaa Donation Foundation., [star][star] Reprint requests: Yoshio Yoneyama, MD, Nippon Medical School, Department of Obstetrics and Gynecology, 1-1-5, Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
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- 2000
10. Role of adenosine in regulation of brain temperature in fetal sheep
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Suzuki, Shunji and Power, Gordon G.
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Body temperature -- Regulation ,Adenosine -- Physiological aspects ,Fetus -- Physiological aspects ,Health - Abstract
Adenosine does not appear to play a major role in regulating brain temperature when oxygen levels drop. In a study of fetal lambs, brain temperature decreased during low oxygen levels despite the use of a drug that blocks adenosine.
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- 1999
11. Evidence for mechanisms of the acute-phase response to endotoxin in late-gestation fetal goats
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Yoneyama, Yoshio, Sawa, Rintaro, Kubonoya, Kiyoshi, Suzuki, Shunji, Otsubo, Yasuo, Power, Gordon G., and Araki, Tsutomu
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Antipyretics -- Physiological aspects ,Endotoxins -- Physiological aspects ,Fetus -- Physiological aspects ,Health - Abstract
The production of chemicals that suppress fever may explain why endotoxins do not cause fever in human and animal fetuses. Endotoxins are produced by bacteria during bacterial infections. The endotoxin stimulates the production of prostaglandins in the body, which then produce fever. Researchers measured the concentration of various chemicals produced in response to endotoxins in fetal goats. The goats did not develop fever, and this may be due to the fact that prostaglandin levels did not increase but the levels of arginine vasopressin did increase. Arginine vasopressin is known to suppress fever.
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- 1998
12. The relationship between uterine artery Doppler velocimetry and umbilical venous adenosine levels in pregnancies complicated by preeclampsia
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Yoneyama, Yoshio, Sawa, Rintaro, Suzuki, Shunji, Shin, Sumio, Power, Gordon G., and Araki, Tsutomu
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Pregnant women -- Analysis ,Pregnancy -- Analysis ,Preeclampsia -- Analysis ,Health - Abstract
Byline: Yoshio Yoneyama, Rintaro Sawa, Shunji Suzuki, Sumio Shin, Gordon G. Power, Tsutomu Araki Keywords: Placenta; adenosine; pulsatility index; uterine artery Abstract: OBJECTIVE: The aim of this study was to evaluate the relationship between uteroplacental circulatory insufficiency and the fetoplacental release of adenosine in pregnancies complicated by preeclampsia. STUDY DESIGN: We performed uterine artery Doppler velocimetry and calculated the pulsatility index of the uterine artery, to detect uteroplacental circulatory insufficiency, immediately before cordocentesis in 39 pregnant women complicated by preeclampsia. Umbilical venous blood obtained by cordocentesis was then analyzed for blood gases, pH, and plasma adenosine levels. Increased plasma adenosine was taken to signal its increased release from the placenta and fetus relative to its rate of disappearance. RESULTS: The mean umbilical venous plasma adenosine level in the abnormal pulsatility index group was 1.78 [+ or -] 0.17 [mu]mol/L (mean [+ or -] SEM, n = 25), significantly higher than in the normal pulsatility index group 0.58 [+ or -] 0.14 [mu]mol/L (n = 14, p < 0.001). Furthermore, in the abnormal pulsatility index group the elevation of plasma adenosine levels in the umbilical vein was found even in normoxic fetuses. CONCLUSION: Fetal plasma adenosine increases before uteroplacental circulatory insufficiency becomes severe enough to cause generalized fetal hypoxemia. We postulate that enhanced adenosine formation in the fetus, umbilical cord vessels, and particularly the placenta may, at least in part, contribute to control and maintenance of placental blood flow. (AM J OBSTET GYNECOL 1996;174:267-71.) Author Affiliation: Tokyo, Japan, and Loma Linda, California Article History: Received 1 November 1994; Revised 21 April 1995; Accepted 15 May 1995 Article Note: (footnote) [star] From the Department of Obstetrics and Gynecology, Nippon Medical School,a and the Center for Perinatal Biology, b Loma Linda University. , [star][star] Supported by grants-in-aid (No. 06671695 and No. 06454480) from the Ministry of Education, Science, and Culture., a Reprint requests: Yoshio Yoneyama, MD, Nippon Medical School, Department of Obstetrics and Gynecology, 1-1-5, Sendagi, Bunkyo-ku, Tokyo, 113 Japan., aa 0002-9378/96 $5.00 + 0 6/1/66304
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- 1996
13. Cell design of gray-scale thin-film-transistor-driven liquid crystal displays
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Takano, Hideo, Suzuki, Shunji, and Hatoh, Hitoshi
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Thin-Film Electroluminescent Displays ,Technology ,LCD Display ,System Design ,Theoretical Approach ,Liquid crystal displays -- Design and construction ,Video monitors -- Design and construction ,Thin films -- Usage - Published
- 1992
14. Postpartum care services and multi-disciplinary collaboration in Japan
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Suzuki, Shunji
- Abstract
The Postpartum Care Services (PCS) programme in Japan is intended to promote physical recovery and psychological rest for mothers and their children after discharge from the delivery facility, as well as nurture the mothers’ own self-care skills and support healthy childrearing for mothers, children and their families. The subsidies for PCS are based on cooperation between psychiatry and obstetrics and between multiple professions, including the local government. The services should also be implemented based on the instruction to medical institutions and the local governments that they should actively screen and approach pregnant women in need of support. This narrative review describes the challenges of expanding the PCS programme nationwide in Japan.
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- 2024
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15. Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry
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Sawhney, Jitendra PS., Kothiwale, Veerappa A., Bisne, Vikas, Durgaprasad, Rajashekhar, Jadhav, Praveen, Chopda, Manoj, Vanajakshamma, Velam, Meena, Ramdhan, Vijayaraghavan, Govindan, Chawla, Kamaldeep, Allu, Jagan, Pieper, Karen S., John Camm, A., Kakkar, Ajay K., Kakkar, Ajay K., Bassand, Jean-Pierre, John Camm, A., Fitzmaurice, David A., Goldhaber, Samuel Z., Goto, Shinya, Haas, Sylvia, Hacke, Werner, Mantovani, Lorenzo G., Misselwitz, Frank, Pieper, Karen S., Turpie, Alexander G.G., van Eickels, Martin, Verheugt, Freek W.A., John Camm, A., Bassand, Jean-Pierre, Goldhaber, Samuel Z., Haas, Sylvia, Kayani, Gloria, Mantovani, Lorenzo G., Fox, Keith A.A., Gersh, Bernard J., Luciardi, Hector Lucas, Gibbs, Harry, Brodmann, Marianne, Cools, Frank, Barretto, Antonio Carlos Pereira, Connolly, Stuart J., Spyropoulos, Alex, Eikelboom, John, Corbalan, Ramon, Hu, Dayi, Jansky, Petr, Nielsen, Jørn Dalsgaard, Ragy, Hany, Raatikainen, Pekka, Le Heuzey, Jean-Yves, Darius, Harald, Keltai, Matyas, Kakkar, Sanjay, Sawhney, Jitendra Pal Singh, Agnelli, Giancarlo, Ambrosio, Giuseppe, Koretsune, Yukihiro, Sánchez Díaz, Carlos Jerjes, Ten Cate, Hugo, Atar, Dan, Stepinska, Janina, Panchenko, Elizaveta, Lim, Toon Wei, Jacobson, Barry, Oh, Seil, Viñolas, Xavier, Rosenqvist, Marten, Steffel, Jan, Angchaisuksiri, Pantep, Oto, Ali, Parkhomenko, Alex, Al Mahmeed, Wael, Fitzmaurice, David, Goldhaber, Samuel Z., Hu, D.Y., Chen, K.N., Zhao, Y.S., Zhang, H.Q., Chen, J.Z., Cao, S.P., Wang, D.W., Yang, Y.J., Li, W.H., Yin, Y.H., Tao, G.Z., Yang, P., Chen, Y.M., He, S.H., Wang, Ying, Wang, Yong, Fu, G.S., Li, X., Wu, T.G., Cheng, X.S., Yan, X.W., Zhao, R.P., Chen, M.S., Xiong, L.G., Chen, P., Jiao, Y., Guo, Y., Xue, L., Wang, F.Z., Li, H., Yang, Z.M., Bai, C.L., Chen, J., Chen, J.Y., Chen, X., Feng, S., Fu, Q.H., Gao, X.J., Guo, W.N., He, R.H., He, X.A., Hu, X.S., Huang, X.F., Li, B., Li, J., Li, L., Li, Y.H., Liu, T.T., Liu, W.L., Liu, Y.Y., Lu, Z.C., Luo, X.L., Ma, T.Y., Peng, J.Q., Sheng, X., Shi, X.J., Sun, Y.H., Tian, G., Wang, K., Wang, L., Wu, R.N., Xie, Q., Xu, R.Y., Yang, J.S., Yang, L.L., Yang, Q., Yang, Y.J., Ye, Y., Yu, H.Y., Yu, J.H., Yu, T., Zhai, H., Zhan, Q., Zhang, G.S., Zhang, Q., Zhang, R., Zhang, Y., Zheng, W.Y., Zhou, B., Zhou, Z.H., Zhu, X.Y., Kakkar, S., Sawhney, J.P.S., Jadhav, P., Durgaprasad, R., Ravi Shankar, A.G., Rajput, R.K., Bhargava, K., Sarma, R., Srinivas, A., Roy, D., Nagamalesh, U.M., Chopda, M., Kishore, R., Kulkarni, G., Chandwani, P., Pothiwala, R.A., Padinhare Purayil, M., Shah, S., Chawla, K., Kothiwale, V.A., Raghuraman, B., Vijayaraghavan, G., Vijan, V.M., Bantwal, G., Bisne, V., Khan, A., Gupta, J.B., Kumar, S., Jain, D., Abraham, S., Adak, D., Barai, A., Begum, H., Bhattacharjee, P., Dargude, M., Davies, D., Deshpande, B., Dhakrao, P., Dhyani, V., Duhan, S., Earath, M., Ganatra, A., Giradkar, S., Jain, V., Karthikeyan, R., Kasala, L., Kaur, S., Krishnappa, S., Lawande, A., Lokesh, B., Madarkar, N., Meena, R., More, P., Naik, D., Prashanth, K., Rao, M., Rao, N.M., Sadhu, N., Shah, D., Sharma, M., Shiva, P., Singhal, S., Suresh, S., Vanajakshamma, V., Panse, S.G., Koretsune, Y., Kanamori, S., Yamamoto, K., Kumagai, K., Katsuda, Y., Sadamatsu, K., Toyota, F., Mizuno, Y., Misumi, I., Noguchi, H., Ando, S., Suetsugu, T., Minamoto, M., Oda, Hiroshi, Shiraishi, K., Adachi, S., Chiba, K., Norita, H., Tsuruta, M., Koyanagi, T., Yamamoto, K., Ando, H., Higashi, T., Okada, K., Azakami, S., Komaki, S., Kumeda, K., Murayama, T., Matsumura, J., Oba, Y., Sonoda, R., Goto, K., Minoda, K., Haraguchi, Y., Suefuji, H., Miyagi, H., Kato, H., Nakamura, Tadashi, Nakamura, Tsugihiro, Nandate, H., Zaitsu, R., Fujiura, Yoshihisa, Yoshimura, A., Numata, H., Ogawa, J., Tatematsu, H., Kamogawa, Y., Murakami, K., Wakasa, Y., Yamasawa, M., Maekawa, H., Abe, S., Kihara, H., Tsunoda, S., Saito, Katsumi, Saito, Kazuyuki, Fudo, T., Obunai, K., Tachibana, H., Oba, I., Kuwahata, T., Higa, S., Gushiken, M., Eto, T., Yoshida, H., Ikeda, D., Fujiura, Yoshitake, Ishizawa, M., Nakatsuka, M., Murata, K., Ogurusu, C., Shimoyama, M., Akutsu, M., Takamura, I., Hoshino, F., Yokota, N., Iwao, T., Tsuchida, K., Takeuchi, M., Hatori, Y., Kitami, Y., Nakamura, Yoichi, Oyama, R., Ageta, M., Oda, Hiroyuki, Go, Y., Mishima, K., Unoki, T., Morii, S., Shiga, Yuhei, Sumi, H., Nagatomo, T., Sanno, K., Fujisawa, K., Atsuchi, Y., Nagoshi, T., Seto, T., Tabuchi, T., Kameko, M., Nii, K., Oshiro, K., Takezawa, H., Nagano, S., Miyamoto, N., Iwaki, M., Nakamura, Yuichiro, Fujii, M., Okawa, M., Abe, Masahiko, Abe, Masatake, Abe, Mitsunori, Saito, T., Mito, T., Nagao, K., Minami, J., Mita, T., Sakuma, I., Taguchi, T., Marusaki, S., Doi, H., Tanaka, M., Fujito, T., Matsuta, M., Kusumoto, T., Kakinoki, S., Ashida, K., Yoshizawa, N., Agata, J., Arasaki, O., Manita, M., Ikemura, M., Fukuoka, S., Murakami, H., Matsukawa, S., Hata, Y., Taniguchi, T., Ko, T., Kubo, H., Imamaki, M., Akiyama, M., Inagaki, M., Odakura, H., Ueda, T., Katsube, Y., Nakata, A., Watanabe, H., Techigawara, M., Igarashi, M., Taga, K., Kimura, T., Tomimoto, S., Shibuya, M., Nakano, M., Ito, K., Seo, T., Hiramitsu, S., Hosokawa, H., Hoshiai, M., Hibino, M., Miyagawa, K., Horie, Hajime, Sugishita, N., Shiga, Yukio, Soma, A., Neya, K., Yoshida, Tetsuro, Yoshida, Tomoki, Mizuguchi, M., Ishiguro, M., Minagawa, T., Wada, M., Mukawa, H., Okuda, F., Nagasaka, S., Abe, Y., Adachi, Sen, Adachi, Susumu, Adachi, T., Akahane, K., Amano, T., Aoki, K., Aoyama, T., Arai, H., Arima, S., Arino, T., Asano, H., Asano, T., Azuma, J., Baba, T., Betsuyaku, T., Chibana, H., Date, H., Doiuchi, J., Emura, Y., Endo, M., Fujii, Y., Fujiki, R., Fujisawa, A., Fujisawa, Y., Fukuda, T., Fukui, T., Furukawa, N., Furukawa, T., Furumoto, W., Goto, T., Hamaoka, M., Hanazono, N., Hasegawa, K., Hatsuno, T., Hayashi, Y., Higuchi, K., Hirasawa, K., Hirayama, H., Hirose, M., Hirota, S., Honda, M., Horie, Hideki, Ido, T., Iiji, O., Ikeda, H., Ikeda, K., Ikeoka, K., Imaizumi, M., Inaba, H., Inoue, T., Iseki, F., Ishihara, A., Ishioka, N., Ito, N., Iwase, T., Kakuda, H., Kamata, J., Kanai, H., Kanda, H., Kaneko, M., Kano, H., Kasai, T., Kato, T., Kato, Y., Kawada, Y., Kawai, K., Kawakami, K., Kawakami, S., Kawamoto, T., Kawano, S., Kim, J., Kira, T., Kitazawa, H., Kitazumi, H., Kito, T., Kobayashi, T., Koeda, T., Kojima, J., Komatsu, H., Komatsu, I., Koshibu, Y., Kotani, T., Kozuka, T., Kumai, Y., Kumazaki, T., Maeda, I., Maeda, K., Maruyama, Y., Matsui, S., Matsushita, K., Matsuura, Y., Mineoi, K., Mitsuhashi, H., Miura, N., Miyaguchi, S., Miyajima, S., Miyamoto, H., Miyashita, A., Miyata, S., Mizuguchi, I., Mizuno, A., Mori, T., Moriai, O., Morishita, K., Murai, O., Nagai, Sho, Nagai, Shunichi, Nagata, E., Nagata, H., Nakagomi, A., Nakahara, S., Nakamura, M., Nakamura, R., Nakanishi, N., Nakayama, T., Nakazato, R., Nanke, T., Nariyama, J., Niijima, Y., Niinuma, H., Nishida, Y., Nishihata, Y., Nishino, K., Nishioka, H., Nishizawa, K., Niwa, I., Nomura, K., Nomura, S., Nozoe, M., Ogawa, T., Ohara, N., Okada, M., Okamoto, K., Okita, H., Okuyama, M., Ono, H., Ono, T., Onuki Pearce, Y., Oriso, S., Ota, A., Otaki, E., Saito, Y., Sakai, H., Sakamoto, N., Sakamoto, Y., Samejima, Y., Sasagawa, Y., Sasaguri, H., Sasaki, A., Sasaki, T., Sato, Kazuki, Sato, Kiyoharu, Sawano, M., Seki, S., Sekine, Y., Seta, Y., Sezaki, K., Shibata, N., Shiina, Y., Shimono, H., Shimoyama, Y., Shindo, T., Shinohara, H., Shinohe, R., Shinozuka, T., Shirai, T., Shiraiwa, T., Shozawa, Y., Suga, T., Sugimoto, C., Suzuki, Kazuo, Suzuki, Keita, Suzuki, Shu, Suzuki, Shunji, Suzuki, Susumu, Suzuki, Y., Tada, M., Taguchi, A., Takagi, T., Takagi, Y., Takahashi, K., Takahashi, S., Takai, H., Takanaka, C., Take, S., Takeda, H., Takei, K., Takenaka, K., Tana, T., Tanabe, G., Taya, K., Teragawa, H., Tohyo, S., Toru, S., Tsuchiya, Y., Tsuji, T., Tsuzaki, K., Uchiyama, H., Ueda, O., Ueda, T., Ueyama, Y., Wakaki, N., Wakiyama, T., Washizuka, T., Watanabe, M., Yamada, T., Yamagishi, T., Yamaguchi, H., Yamamoto, Kenichi, Yamamoto, Kentaro, Yamamoto, Kunihiko, Yamamoto, T., Yamaura, M., Yamazoe, M., Yasui, K., Yokoyama, Y., Yoshida, K., Lim, T.W., Ching, C.K., Foo, C.G., Chow, J.H., Chen, D.D., Jaufeerally, F.R., Lee, Y.M., Li, H., Lim, G., Lim, W.T., Thng, S., Yap, S.Y., Yeo, C., Oh, S., Pak, H.N., Kim, J.-B., Kim, J.H., Jang, S.-W., Kim, D.H., Kim, J., Ryu, D.R., Park, S.W., Kim, D.-K., Choi, D.J., Oh, Y.S., Cho, M.-C., Kim, S.-H., Jeon, H.-K., Shin, D.-G., Park, J.S., Park, H.K., Han, S.-J., Sung, J.H., Cho, J.-G., Nam, G.-B., On, Y.K., Lim, H.E., Kwak, J.J., Cha, T.-J., Hong, T.J., Park, S.H., Yoon, J.H., Kim, N.-H., Kim, K.-S., Jung, B.C., Hwang, G.-S., Kim, C.-J., Park, J.S., Kim, D.B., Ahn, J.J., An, H.J., Bae, H., Baek, A.L., Chi, W.J., Choi, E.A., Choi, E.H., Choi, H.K., Choi, H.S., Han, S., Heo, E.S., Her, K.O., Hwang, S.W., Jang, E.M., Jang, H.-S., Jang, S., Jeon, H.-G., Jeon, S.R., Jeon, Y.R., Jeong, H.K., Jung, I.-A., Kim, Hyeon Jeong, Kim, Hyun Ju, Kim, Ji Seon, Kim, Jung Sook, Kim, J.A., Kim, K.T., Kim, M.S., Kim, Sang Hee, Kim, Sang Hyun, Kim, Y.-I., Lee, C.S., Lee, E.H., Lee, G.H., Lee, H.Y., Lee, H.-Y., Lee, K.H., Lee, K.R., Lee, M.S., Lee, M.-Y., Lee, R.W., Lee, S.E., Lee, S.H., Lee, S., Lee, W.Y., Noh, I.K., Park, A.R., Park, B.R., Park, H.N., Park, J.H., Park, M., Park, Y., Seo, S.-Y., Shim, J., Sim, J.H., Sohn, Y.M., Son, W.S., Son, Y.S., Song, H.J., Wi, H.K., Woo, J.J., Ye, S., Yim, K.H., Yoo, K.M., Yoon, E.J., Yun, S.Y., Angchaisuksiri, P., Chawanadelert, S., Mongkolwongroj, P., Kanokphatcharakun, K., Cheewatanakornkul, S., Laksomya, T., Pattanaprichakul, S., Chantrarat, T., Rungaramsin, S., Silaruks, S., Wongcharoen, W., Siriwattana, K., Likittanasombat, K., Katekangplu, P., Boonyapisit, W., Cholsaringkarl, D., Chatlaong, B., Chattranukulchai, P., Santanakorn, Y., Hutayanon, P., Khunrong, P., Bunyapipat, T., Jai-Aue, S., Kaewsuwanna, P., Bamungpong, P., Gunaparn, S., Hongsuppinyo, S., Inphontan, R., Khattaroek, R., Khunkong, K., 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- Abstract
The Global Anticoagulant Registry in the FIELD–Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry.
- Published
- 2018
- Full Text
- View/download PDF
16. Inhibitory effect of chitinases isolated from Semillon grapes (Vitis vinifera) on growth of grapevine pathogens
- Author
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Saito, Seiya, Odagiri, Masanori, Furuya, Seiichi, Suzuki, Shunji, and Takayanagi, Tsutomu
- Abstract
Abstract: Characteristics and antifungal activity of chitinases in Semillon grapes were investigated. Chitinases were isolated from the juice of Semillon grapes by chitin affinity chromatography. Native and SDS-PAGE analyses of the fraction showing chitin affinity (active fraction) demonstrated only the presence of protein bands of chitinases. Three types of class IV chitinases (chi-1a, chi-1b and chi-2) were purified from the active fraction. These chitinases actively hydrolyzed chitin under acidic conditions (pH 4.0–4.5). The isoelectric points and the molecular weights of chi-1a, chi-1b and chi-2 were 4.73, 4.60, and 7.87, and 32.1 kDa, 31.6 kDa, and 29.0 kDa, respectively. The active fraction was found to inhibit Botrytis cinerea mycelial growth and the inhibitory effect was due to the activity of chitinases. The active fraction inhibited twenty strains of B. cinerea collected from the experimental vineyard. The effect of chitinases was enhanced in media containing more than 20% sugar. When the active fraction was tested on Glomerella cingulata, the growth inhibitory effect observed was markedly less than that seen on B. cinerea.
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- 2011
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17. Molecular characterization of Japanese indigenous grape cultivar ‘Koshu’ (Vitis vinifera) leaf and berry skin during grape development
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Kobayashi, Hironori, Fujita, Keiko, Suzuki, Shunji, and Takayanagi, Tsutomu
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Abstract: We investigated the transcriptional profiles of Japanese indigenous grape cultivar ‘Koshu’ (Vitis vinifera) leaf and berry skin during ripening. In leaf, 64 genes were abundantly transcribed at the end of véraison (14 weeks post-flowering), whereas the expression of 61 genes was upregulated at the end of ripening (20 weeks post-flowering). In berry skin, 67 genes were abundantly transcribed at the end of véraison, whereas the expression of 86 genes was upregulated at the end of ripening. Gene expression associated with biological processes was activated in both tissues at the end of ripening. The expression of genes associated with photosynthesis, sugar synthesis, anthocyanin synthesis, cinnamic acid synthesis, and amino acid metabolism was observed in leaf and berry skin during ripening, together with the accumulation of sugars, anthocyanins, cinnamic acids, and amino acids. Transcripts of AUX/IAA family proteins that repress the activities of auxin-induced proteins were expressed in berry skin at the end of véraison. Transcripts of genes related to the ubiquitin–proteasome system that degrades AUX/IAA family proteins were abundantly expressed in berry skin at the end of ripening, suggesting that the expansion of skin cells at véraison is suppressed by AUX/IAA family proteins, and that the ubiquitin–proteasome system induces the expansion of skin cells during ripening by degrading AUX/IAA family proteins. These transcriptional profiles, which provide new information on the characteristics of ‘Koshu’ grapevine during ripening, may explain the unique characteristics of ‘Koshu’ grape in comparison with those of European grapes used for winemaking, and may contribute to the improvement of ‘Koshu’ grape quality.
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- 2009
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18. Maternal Peripheral T-Helper 1-Type and T-Helper 2-Type Immunity in Nonpreeclamptic Twin Pregnancies
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Suzuki, Shunji, Kuwajima, Toyohiko, Yoneyama, Yoshio, Sawa, Rintaro, and Araki, Tsutomu
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The percentage of T-helper (Th)1, Th2 cells and the Th1:Th2 cell ratios in peripheral blood from 14 normal nonpregnant women, 23 normal pregnant women and 9 patients with twin pregnancies without preeclampsia at 28–32 weeks’ gestation were calculated using flow cytometry. In normal pregnant women, the percentage of Th1 cells and Th1:Th2 ratios were significantly lower than those in nonpregnant women. In twin pregnancies, the percentage of Th1 cells and the Th1:Th2 ratios were significantly lower than those in nonpregnancies. In twin pregnancies; in addition, the percentage of Th1 cells was significantly lower than that in singleton pregnancies. Our findings show a markedly predominant Th2 immunity in twin pregnancies.
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- 2002
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19. Regulation of Plasma Adenosine Levels in Normal Pregnancy
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Yoneyama, Yoshio, Sawa, Rintaro, Suzuki, Shunji, Ishino, Hiroshi, Miura, Atsushi, Kuwabara, Yoshimitsu, Kuwajima, Toyohiko, Ito, Naoko, Kiyokawa, Yasuko, Otsubo, Yasuo, and Araki, Tsutomu
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The aim of this study was to investigate the possible mechanism of the regulation of plasma adenosine concentration [ADO] in normal pregnancy. We measured the activities of circulating enzymes that are involved in the production and metabolism of adenosine, and plasma [ADO] in nonpregnant (n = 14) and normal pregnant women (n = 14) in the third trimester. In pregnant women, the activity of plasma 5′-nucleotidase and plasma [ADO] were significantly elevated and plasma adenosine deaminase activity was significantly reduced. Enzymatic activities of both plasma enzymes appear to be changed in a way that would favor increased adenosine concentrations.
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- 2002
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20. Relation between Plasma Endothelin 1 Levels and T Helper 1: T Helper 2 Cell Immunity in Women with Preeclampsia
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Kuwajima, Toyohiko, Suzuki, Shunji, Yoneyama, Yoshio, Sawa, Rintaro, Asakura, Hirobumi, and Araki, Tsutomu
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The aim of this study was to investigate the relationship between plasma endothelin 1 (ET-1) levels and T helper (Th)-1:Th2 cell immunity in women with preeclampsia. The percentage of Th1 and Th2 cells and the Th1:Th2 cell ratios in peripheral blood from 11 normal pregnant women and 11 patients with preeclampsia at 29–34 weeks of gestation were calculated using flow cytometry. The plasma ET-1 level was also determined using a modified radioimmunoassay. The plasma ET-1 concentrations and the Th1:Th2 cell ratios in normal pregnancies were significantly lower than those in patients with preeclampsia. Negative correlations were found between plasma ET-1 levels and Th2 cells in both the preeclamptic pregnancy groups and in the normal pregnant women. Our results indicate that elevated ET-1 levels are associated with a Th1:Th2 imbalance in preeclampsia.
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- 2001
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21. Relation between Serum Uric Acid and Plasma Adenosine Levels in Women with Preeclampsia
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Suzuki, Shunji, Yoneyama, Yoshio, Sawa, Rintaro, Otsubo, Yasuo, Takeuchi, Tsutomu, and Araki, Tsutomu
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The aim of this study was to examine the relationship between plasma adenosine and serum uric acid levels in women with preeclampsia. Maternal arterial blood sampling was performed to measure serum uric acid and plasma adenosine levels in 20 pregnant women complicated by preeclampsia and 22 normal pregnant women at 33–38 weeks of gestation. The average plasma adenosine levels were 0.31 ± 0.12 µmol/l in the normal pregnant group and 0.45 ± 0.11 µmol/l in the preeclampsia group. The mean serum uric acid level in women with preeclampsia was 5.9 ± 0.60 mg/dl, significantly higher than in the normal pregnant women (4.4 ± 0.69 mg/dl). Positive correlations were found between serum uric acid and plasma adenosine levels in both the group with (r
2 = 0.38, p < 0.05) and the group without (r2 = 0.54, p < 0.05) preeclampsia. There was also a significant correlation between serum uric acid and plasma adenosine levels on the whole (r2 = 0.59, p < 0.05). Our results suggest that increased adenosine is a contributing source of preeclamptic hyperuricemia.- Published
- 2001
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22. Plasma adenosine levels and P-selectin expression on platelets in preeclampsia
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Yoneyama, Yoshio, Suzuki, Shunji, Sawa, Rintaro, Kiyokawa, Yasuko, Power, Gordon G, and Araki, Tsutomu
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Objective: To measure the correlation of plasma adenosine levels with platelet activation in women with preeclampsia.
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- 2001
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23. Correlation between Grade III Placenta and Plasma Antithrombin III Activity in Full Term Pregnancy
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Asakura, Hirobumi, Ohshita, Tomoko, Suzuki, Shunji, and Araki, Tsutomu
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We evaluated whether the presence of a grade III placenta correlates with blood hypercoagulability in pregnancy between 37 and 39 weeks of gestation. The placenta was graded by ultrasound in 155 healthy full-term women and the plasma levels of antithrombin III (AT III) activity, thrombin-antithrombin complex (TAT) and D-dimer were correlated with each placental grade. AT III activity levels tended to decrease with advancing placental grade from I to III (p < 0.05). D-dimer showed the same tendency while TAT did not. The incidence of reduced AT III activity levels (<70%) in women with a grade III placenta was about twice those in women with a grade II or I placenta, and that of AT III <80% was 3-fold greater. We concluded that the presence of a grade III placenta in full-term pregnancies correlates with blood hypercoagulability.
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- 2001
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24. Regulation of Platelet Aggregation in vitro by Plasma Adenosine in Preeclampsia
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Takeuchi, Tsutomu, Yoneyama, Yoshio, Suzuki, Shunji, Sawa, Rintaro, Otsubo, Yasuo, and Araki, Tsutomu
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The aim of this study was to evaluate the possible role of plasma adenosine in platelet aggregation in preeclampsia. We measured the plasma adenosine concentration [ADO] and in vitro platelet aggregation in the third trimester of normal pregnant (n = 15) and preeclamptic women (n = 15). The mean plasma [ADO] in preeclampsia was 0.68 ± 0.08 µM(means ± SEM), significantly higher than in normal pregnancy (0.42 ± 0.09 µM) (p < 0.05). In preeclampsia, platelet aggregation in response to collagen was approximately 40% lower than that in normal pregnancy (p < 0.05). There was an inverse correlation between the plasma [ADO] and platelet aggregation in vitro (r = –0.27, p < 0.05). These results suggest reduced platelet aggregation in preeclampsia may be at least in part attributed to an elevation of the the plasma [ADO].
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- 2001
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25. Morphine Upregulates mu Opioid Receptors of Human and Monkey Lymphocytes
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Suzuki, Shunji, Miyagi, Tomoko, Chuang, Teddy K., Chuang, Linda F., Doi, Roy H., and Chuang, Ronald Y.
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Opioid receptors of subtypes delta, kappa, and mu similar to those found in brain cells have been identified in immune cells. The current study demonstrates by competitive polymerase chain reaction the treatment of human lymphocytic cells with morphine resulting in an increased amount of gene expression of mu opioid receptors. Antibodies against the MOR-1, the neuronal mu opioid receptor, were used in Western blot analysis of mu proteins and the results revealed a single band of ∼50 kDa, the intensity of which was increased by morphine treatment. Similar results of mu opioid receptor activation were observed when monkey lymphocytes were treated with morphine. These studies suggest that in addition to causing an immune effect through communication with the neuroendocrine system, the psychoactive drug morphine may modulate immune functions by acting directly on the mu opioid receptors expressed on lymphocytes.
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- 2000
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26. Relation Between Serum Uric Acid and Plasma Adenosine Levels in Twin Pregnancies
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SUZUKI, SHUNJI, YONEYAMA, YOSHIO, SAWA, RINTARO, and ARAKI, TSUTOMU
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To examine the relationship between plasma adenosine and serum uric acid levels in women with singleton and twin pregnancies.
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- 2000
27. Changes in Plasma Adenosine Concentrations during Normal Pregnancy
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Yoneyama, Yoshio, Suzuki, Shunji, Sawa, Rintaro, Takeuchi, Tsutomu, Kobayashi, Hajime, Takei, Rintaro, Kiyokawa, Yasuko, Otsubo, Yasuo, Hayashi, Zuisei, and Araki, Tsutomu
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The aim of this study was to measure changes in plasma adenosine concentration [ADO] during a normal pregnancy and to evaluate the possible role of platelets and red blood cells (RBC) as causes of changes in plasma [ADO]. We measured the plasma [ADO] in normal pregnant women (n = 11) during the first, second and third trimesters. The mean plasma [ADO] in the third trimester was 0.41 ± 0.08 μM (means ± SEM), significantly higher than in the first and second trimesters (p < 0.05). In pregnant women, platelet and RBC counts, hematocrit and hemoglobin concentration decreased slightly throughout the pregnancy. The elevation in the plasma [ADO] correlated inversely with the platelet count (r = –0.43, p < 0.05). These results suggest that an increase in the plasma [ADO] in the third trimester may be attributed to the enhanced adenosine release from activated platelets.
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- 2000
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28. Hyperthermia Prevent Metabolic and Cerebral Flow Responses to Hypoxia in the Fetal Sheep
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Suzuki, Shunji, Murata, Tomoaki, Jiang, Lan, and Power, Gordon G.
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Objective:Fetal brain temperature has been found to decrease during hypoxia, strongly suggesting a reduction in cerebral O2consumption and increases in cerebral blood flow. These responses may protect the brain in part against hypoxic injury. This study was undertaken to examine whether these compensatory mechanisms are lost during fetal hyperthemia.Methods:Intermittent fetal hypoxemia was induced by administering low-O2gas mixtures to nine neart-term ewes Fetal brain and body core temperature responses were measured with and without fetal hyperthermia induced by circulating warm water through a plastic coil looped about the fetus in utero.Results:In normothermic fetuses, fetal brain temperature relative to core decreased during a 30-minute period of hypoxia and then returned to normal during recovceyr. This response may be explaiend by a combination of cerebral hypometabolism and increased cerebral blood flow. However, in hyperthemic fetuses (intrauterine warming for 1 hour, raising body core and brain temperatures 0.66 ± 0.06 and 0.61 ± 0.10C, respectively) a subsequent period of hypoxia no longer induced a reduction in brain temperature relative to body core.Conclusion:When temperature of the fetal sheep is elevated, as may occur with maternal fever, prolonged exercise, and elevated environmental temperatures, the fetal brain is less well protected against hypoxic injury.
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- 2000
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29. Clinical Trial of Induction of Labor versus Expectant Management in Twin Pregnancy
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Suzuki, Shunji, Otsubo, Yasuo, Sawa, Rintaro, Yoneyama, Yoshio, and Araki, Tsutomu
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Objective:The appropriate date of delivery in twin pregnancies is supposed to be earlier than that in singleton pregnancy. The aim of this study was to compare two strategies for managing twin pregnancies (i.e., immediate induction and expectant management). Methods:Seventeen patients underwent immediately induced labor by administration of oral prostaglandin E
2 at 37 weeks, while 19 patients underwent expectant management. Results:The average gestational age at delivery in the induction group was 37.5 ± 0.4 weeks, significantly earlier than that in the expectant management group (39.0 ± 1.1 weeks). However, there were no significant differences in the average birth weight between the two groups (2,700 ± 330 g in the induction group vs. 2,672 ± 392 g in the expectant management group). The cesarean delivery rate in the induction group was 18%, not significantly different from that in the expectant management group (32%). The most common indication for cesarean section in the expectant management group was maternal infection, while there was no maternal infection in the induction group (p = 0.08). Conclusion:It may be acceptable do intervene in twin pregnancies earlier than in singleton pregnancies during term.- Published
- 2000
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30. Fibrin D-Dimer in Thrombogenic Disorders
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Matsuo, Takefumi, Kobayashi, Hiroko, Kario, Kazuomi, and Suzuki, Shunji
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- 2000
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31. Maternal plasma adenosine levels in pregnancies complicated by toxemia
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Suzuki, Shunji, Yoneyama, Yoshio, Sawa, Rintaro, Takeuchi, Tsutomu, Power, Gordon G., and Araki, Tsutomu
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- 1999
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32. Iatrogenic Monoamniotic Twin Gestation with Progressive Twin-Twin Transfusion Syndrome
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Suzuki, Shunji, Ishikawa, Gen, Sawa, Rintaro, Yoneyama, Yoshio, Otsubo, Yasuo, and Araki, Tsutomu
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AbstractObjective:Intentional puncture of the membrane has been reported to be a promising new method for the management of twin-twin transfusion syndrome. Case Report:Treatment of twin-twin transfusion syndrome with serial amniocenteses resulted in unintentional puncture of the dividing membrane at 24 weeks of gestation. Fetal growth discordance increased, and twin-twin transfusion did not improve following the puncture. Intrauterine death of both fetuses at 27 weeks of gestation occurred. Conclusion:Amniotic septostomy for the treatment of twin-twin transfusion sydnrome should be performed with serious consideration.
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- 1999
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33. Vibration Control of a Steering Wheel Using Piezoelectric Actuators
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Zhu, Ye, Qiu, Jinhao, Tani, Junji, Suzuki, Shunji, Urushiyama, Yuta, and Hontani, Yasuharu
- Abstract
In this paper active control is used to reduce the vibration of a steering wheel without changing static stiffness significantly. Multi-layer piezoelectric actuators are bonded to spokes to actively suppress the vibration of the wheel under environmental disturbance. A FEM model of the wheel is derived using structural analysis software NASTRAN and modified according to experimental data. Four natural vibration modes of the wheel are included in the state space model for control design and the others are neglected. The controller is designed using ji synthesis due to its ability of improving robust stability and robust performance. The digital counterpart of the controller is realized on a PC with A/D and D/A converters. Both simulation and experimental investigations are performed to show the effectiveness of the whole approach. Results show that the vibration level is considerably reduced. And, it is also found that the output capacity of the piezoelectric actuators and the performance of the digital controller are the main obstacles to obtain further improvement of the control performance.
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- 1999
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34. Sonographic evaluation of umbilical cord insertion with umbilical coiling index
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Otsubo, Yasuo, Yoneyama, Yoshio, Suzuki, Shunji, Sawa, Rintaro, and Araki, Tsutomu
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The aim of this study was to investigate the association between umbilical cord hypocoiling and abnormal placental insertion of the umbilical cord. Umbilical coiling was measured by sonography in 253 pregnant women in their second or third trimester. An umbilical coiling index, defined here as the reciprocal of the length of 1 umbilical vascular coil, of less than 0.1 was considered hypocoiled. The distance from the placental edge to the insertion of the umbilical cord was measured after delivery, and the results were used to classify cord insertion as normal, marginal, or velamentous. Cord insertion was abnormal in 66.7% of the fetuses with umbilical hypocoiling but in only 1.3% of those whose coiling index was ≥ 0.1 (p < 0.05). Hypocoiling of the umbilical cord was highly associated with abnormal cord insertion. The presence of a hypocoiled umbilical cord may indicate the presence of abnormal cord insertion and thus may be useful for obstetric management. © 1999 John Wiley & Sons, Inc. J Clin Ultrasound 27:341344, 1999.
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- 1999
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35. Prediction of Oligohydramnios in Prolonged Pregnancy
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Suzuki, Shunji, Otsubo, Yasuo, Sawa, Rintaro, Yoneyama, Yoshio, and Araki, Tsutomu
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A decrease in amniotic fluid in prolonged pregnancy is associated with increased fetal morbidity. However, few investigations have been reported on the prediction of this condition. Fetal renal arterial pulsatility index (PI), hourly fetal urine production rate (HFUPR) and amniotic fluid index (AFI) at 39 weeks were studied in 51 singleton pregnancies with (n = 14) and without oligohydramnios (AFI < 5, n = 37) in prolonged pregnancy. There was no difference in the average fetal renal arterial PI and HFUPR between the oligohydramnios group and the normal group. However, the average AFI in the oligohydramnios group was 7.5 ± 0.9, which was lower than that in the normal group (p < 0.05). We speculated that AFI value at 39 weeks is useful for predicting the incidence of oligohydramnios in prolonged pregnancy.
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- 1999
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36. Fetal Middle Cerebral Artery Doppler Waveforms in Twin–Twin Transfusion Syndrome
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Suzuki, Shunji, Sawa, Rintaro, Yoneyama, Yoshio, Otsubo, Yasuo, and Araki, Tsutomu
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The aim of this study was to compare the fetal middle cerebral artery (MCA) Doppler waveforms in growth-retarded twin fetuses with (n = 11) and without (n = 24) twin–twin transfusion syndrome (TTTS). Umbilical artery (UA) and fetal MCA Doppler velocity waveforms were recorded on admission. The mean values of the UA pulsatility index (PI) of smaller twin fetuses with and without TTTS were significantly higher than those of normal singleton pregnancies. The mean values of the MCA PI of smaller twin fetuses in the TTTS group (+0.7 ± 1 SD) were significantly higher than those of normal singleton pregnancies on admission, and these levels did not markedly change following amniocentesis. On the other hand, the values of the MCA of the growth-retarded fetuses without TTTS (–0.9 ± 1 SD) were significantly lower than those of normal singleton pregnancies. Our findings suggest that measurement of fetal MCA PI is a useful method to assess growth-retarded fetuses in monochorionic twin pregnancies.
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- 1999
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37. Threshold Voltage Biased E-Mode TN LCD - Optimum Optical Design for Grayscale Application
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Takano, Hideo, Ikezaki, Mitsuru, and Suzuki, Shunji
- Abstract
In a normally white (NW) twisted nematic (TN) liquid crystal displays (LCDs), there are two optical eigenmodes, an extraordinary-ray mode (e-mode) and an ordinary-ray mode (o-mode). With zero or a low-bias voltage as the brightest state of the display, both eigenmodes have insufficient display performance for the analog grayscale application. The former has a large color change as a function of viewing zone. The latter has quite a narrow horizontal viewing zone. By applying a threshold voltage as a bias to represent the brightest level of the e-mode NW, the optical performance in the vertical viewing zone was much improved. Further optimization of the d*delta-n for this mode of operation resulted in a small color change and a wide viewing zone by choosing d*delta-n = 0.47 micrometers. We conclude that the threshold-voltage biased e-mode NW of the first-minimum thin-film-transistor (TFT) driven TN can achieve a wide viewing angle for analog-grayscale applications.
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- 1992
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38. Extrinsic Coagulation Factors and Tissue Factor Pathway Inhibitor in End-Stage Chronic Renal Failure
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Matsuo, Takefumi, Koide, Masanobu, Kario, Kazuomi, Suzuki, Shunji, and Matsuo, Miyako
- Abstract
The relationship between extrinsic coagulation factors, tissue factor pathway inhibitor (TFPI) and activated factor XII (FXIIa) was examined in 71 patients with end-stage chronic renal failure. They had chronic stable uremia due to regular hemodialysis. The patients were divided into two age- and sex-matched groups with and without diabetes mellitus. As extrinsic coagulation parameters, FVIIa and FVII antigen (FVIIag), tissue factor antigen and TFPI (the activity and antigen) were measured. FXIIa was measured as a marker of contact activation, and thrombin generation was evaluated using the two markers thrombin-antithrombin III complex and prothrom-bin fragment 1 + 2. In both hemodialysis groups with and without diabetes, significant elevations of FXIIa, FVIIa and tissue factor, with high levels of TFPI, were found. Thus, hyperactivation of the coagulation system was in part compensated by TFPI, and a significant increase in FXIIa could not directly affect FVIIa hyperactivation. No differences of these parameters, except for FVIIag and fragment 1+2, were found between the groups with and without diabetes. It is suggested that the long-term hemodialysis might have masked any differences due to the underlying disease in these two subgroups.
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- 1997
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39. Magnetic properties of melt-spun Sm/sub 10/(Fe,V)/sub 90/N/sub y/ with TbCu/sub 7/-type structure
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Suzuki, Shinya, Suzuki, Shunji, and Yamamoto, Hiroshi
- Abstract
Vanadium substituted Sm/sub 10/(Fe,V)/sub 90/ alloys were prepared by a single roller rapid-quenching method. The melt-spun Sm/sub 10/Fe/sub 82.5/V/sub 7.5/ alloy showed the TbCu/sub 7/-type structure for a wide range of wheel speeds between 15 and 50 m/s, while the Sm/sub 10/Fe/sub 90/ binary alloy showed the same structure at wheel speeds over 45 m/s. It was found that the substitution of vanadium for iron in Sm/sub 10/(Fe,V)/sub 90/ alloys gives a greater range of stability of the TbCu/sub 7/-type structure. Nitrogenation was carried out by heating alloy powders in nitrogen gas. The magnetic properties of Sm/sub 10/Fe/sub 82.5/V/sub 7.5/N/sub /spl nu// powder nitrogenated at 773 K for 6 h were: J/sub r/=0.71 T, H/sub cJ/=535 kA/m (6.7 kOe), and (BH)/sub max/=63.7 kJm/sup 3/.<
> - Published
- 1995
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40. Fetal Circulatory Responses to Maternal Blood Loss
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Suzuki, Shunji, Tateoka, Sachi, Yagi, Shutaro, Ishikawa, Gen, Ohshita, Tomoko, Sawa, Rintaro, Yoneyama, Yoshio, Asakura, Hirobumi, and Araki, Tsutomu
- Abstract
We examined the fetal circulatory responses to maternal blood loss in pregnant women during the third trimester. Seven healthy women with placenta previa and singleton pregnancies underwent phlebotomies in an autologous donation program. Four hundred milliliters of blood was collected within 15 min at 34 and 35 weeks of gestation. Continuous electric recordings of fetal heart rate were performed during the first blood collection, and the maternal uterine artery (UtA), umbilical artery (UmA) and fetal middle cerebral artery (MCA) Doppler velocity waveforms were recorded before, immediately after and 24 h after the second collection in each patient. The average fetal heart rate, maternal UtA and UmA pulsatility indices did not change measurably during or after maternal blood collections. However, the average fetal MCA pulsatility index decreased significantly 24 h after maternal blood loss. The observation of a decrease in fetal MCA pulsatility index may indicate delayed fetal asphyxia following mild maternal hemorrhage.
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- 2001
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41. Amniotic Band Syndrome in Triplet Pregnancy
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Suzuki, Shunji, Yoneyama, Yoshio, Sawa, Rintaro, Sinagawa, Toshiya, Hayashi, Takashi, and Araki, Tsutomu
- Abstract
AbstractWe present a case of amniotic band syndrome leading to encephalocele in one triplet. In this case, discordance in fetal growth was observed at 9 weeks’ gestation, and the amniotic membrane was not recognized in the sac of the smallest fetus. Thus, significant first-trimester growth discordance in multifetal pregnancies suggests congenital anomalies, and examinations considering amniotic band syndrome should be performed. Absence of the amniotic membrane in the gestational sac may be a useful marker of amniotic band syndrome.Copyright © 1999 S. Karger AG, Basel
- Published
- 1999
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42. Fetal brain death and Dandy–Walker malformation
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Otsubo, Yasuo, Yoneyama, Yoshio, Sawa, Rintaro, Suzuki, Shunji, and Araki, Tsutomu
- Abstract
The diagnosis of brain death by Doppler ultrasonography and magnetic resonance imaging is reported in a fetus at 23 weeks' gestation. This is believed to be the first instance in which brain death has been shown in a premature fetus with a brain‐stem anomaly. Copyright © 1999 John Wiley & Sons, Ltd.
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- 1999
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43. Fetal brain death and DandyWalker malformation
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Otsubo, Yasuo, Yoneyama, Yoshio, Sawa, Rintaro, Suzuki, Shunji, and Araki, Tsutomu
- Abstract
The diagnosis of brain death by Doppler ultrasonography and magnetic resonance imaging is reported in a fetus at 23 weeks' gestation. This is believed to be the first instance in which brain death has been shown in a premature fetus with a brain-stem anomaly. Copyright © 1999 John Wiley & Sons, Ltd.
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- 1999
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44. Dependence of laser output on initial photoelectron density in TEA CO2laser
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Suzuki, Shunji, Ishibashi, Yuko, Obara, M., and Fujioka, T.
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- 1980
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45. Structure and magnetic properties of Sm/sub 3/(Fe/sub 0.85/Cr/sub 0.15/)/sub 29/N/sub y/ alloys
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Suzuki, Shunji, Suzuki, Shinya, and Kawasaki, Masahito
- Abstract
The structure and magnetic properties of Sm/sub 3/(Fe/sub 0.85/Cr/sub 0.15/)/sub 29/N/sub y/ alloy were investigated. It was found that the alloy had the R/sub 3/(Fe,M)/sub 29/-type structure and absorbed 4-5 wt.% of nitrogen which exceeds 4 nitrogen atoms per unit formula. The coercivity of the powder was greatly influenced by the nitrogen content and annealing. The Sm/sub 3/(Fe/sub 0.85/Cr/sub 0.15/)/sub 29/N/sub y/ alloy powder with 4.1 wt.% of nitrogen showed a high coercivity of 552 kA/m without fine grinding.
- Published
- 1995
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46. Panel vibration suppression by using piezoelectric damping system
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Erturk, Alper, Suzuki, Shunji, and Yamaguchi, Toshizumi
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- 2019
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47. Case Series of Intrauterine Subamniotic Hemorrhage
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Owada, Momoko, Shibata, Yoshie, and Suzuki, Shunji
- Abstract
We present here 9 cases of intrauterine subamniotic hemorrhage to describe the pathological sequence. The definite diagnosis of subamniotic hemorrhage was mainly made macroscopically with the presence of hemorrhage or hematoma wrapped in the membrane on the fetal surface by postnatal examining of the placenta. In 7 of them (78%), the presence of gradual subamniotic hemorrhage in the second trimester of pregnancy was suspected. In the cases, severe fetal growth restriction and preterm delivery were recognized in 2 (29%) and 4 cases (57%), respectively. In the other 2 cases (22%), acute anemia associated with acute subamniotic hemorrhage was clinically suspected. This may be the first report examining the clinical characteristics of acute or gradual intrauterine subamniotic hemorrhage. Both patterns of subamniotic hemorrhage seemed to be associated with the adverse perinatal outcomes.
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- 2019
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48. The rules of computerized cardiotocography and middle cerebral artery for diagnosis of fetomaternal hemorrhage
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Suzuki, Shunji
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- 2017
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49. Maternal Age and Breastfeeding at 1 Month After Delivery at a Japanese Hospital
- Author
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Suzuki, Shunji
- Published
- 2014
- Full Text
- View/download PDF
50. The Influence of Assisted Reproductive Technology on Growth Discordance in Dichorionic Twin Pregnancies
- Author
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Suzuki, Shunji and Murata, Tomoaki
- Abstract
Adverse perinatal outcomes have been related to growth discordance in twin pregnancies—most often defined as a greater than 20% or 30% difference in birth weights. Both genetic and uteroplacental factors have been implicated. The investigators hypothesized that differing rates of maturation of transferred embryos are associated with discordant birth weights in dichorionic twin pregnancies resulting from assisted reproductive technology (ART). Participating in the study were 101 nulliparous women having dichorionic twin pregnancies that produced male-male or female-female infants. Thirty-eight conceived spontaneously without ovulation induction, and 63 followed in vitro fertilization and embryo transfer. Crown-rump length (CRL) was measured by ultrasonography at 9–11 weeks' gestation. Gestational age was estimated either from the maternal menstrual history as confirmed by ultrasound study of the larger fetus or from the day of oocyte retrieval.
- Published
- 2007
- Full Text
- View/download PDF
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