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Researchers from the University of Oxford have conducted a study on the structural and functional organization of cardiac autonomic control in relation to obesity, fitness, and wellness. The research aims to highlight progress made in the field since 2016 and identify challenges and opportunities for translation. The study emphasizes the importance of targeting specific actuators in the autonomic nervous system to improve outcomes in cardiac pathology. Financial support for this research came from the National Institutes of Health (NIH) in the USA. [Extracted from the article]

A recent study conducted in India examined the morphology of the perforated cervicothoracic ganglion (CTG) in Indian cadavers. The study found that the CTG was observed in 87.5% of the specimens, with the inferior cervical ganglion observed in 12.5% of the specimens. Perforated CTG was found in four specimens exclusively on the left side, where the vertebral artery (VA) pierced at its superior pole or middle. The researchers concluded that understanding this variation is important for preventing complications during therapeutic and diagnostic ganglionic blocks. [Extracted from the article]

A patent application titled "Methods, Agents, And Devices For Local Neuromodulation Of Autonomic Nerves" has been published online. The application describes methods for treating various medical conditions by delivering a small volume of drug formulation locally to target nerve sites in the autonomic nervous system. These methods aim to affect nerve function and treat diseases such as angina, arrhythmias, heart failure, hypertension, pulmonary hypertension, pain, and more. The application also discusses the use of different drug formulations and devices for accessing and monitoring nerve activity. [Extracted from the article]

Researchers from the First Bethune Hospital of Jilin University in Changchun, China, have published a case report on the use of stellate ganglion block (SGB) therapy in managing ventricular electrical storm (VES). VES is a condition characterized by sympathetic overactivity and is associated with ventricular tachycardia (VT) and ventricular arrhythmias (VAs). The case report describes the successful use of SGB in a 60-year-old patient with VT who had previously received pharmacotherapy and implantable cardioverter defibrillator (ICD) therapy. The researchers found that continuous radiofrequency (CRF) therapy was more effective than other methods of SGB, suggesting that CRF ablation of the stellate ganglion could be a potential therapeutic option for refractory VAs. [Extracted from the article]

A recent study from Chengdu University of Traditional Chinese Medicine explores the role of the stellate ganglion (SG) in arrhythmias and its relationship with inflammation. The SG, part of the autonomic nervous system, plays a crucial role in regulating cardiovascular function. Abnormal SG function can lead to disordered cardiac electrical activity and increase the risk of arrhythmias, especially in the context of inflammation. The study suggests that interventions targeting SG function and inflammatory responses may have potential in preventing and treating inflammation-related arrhythmias, providing a new perspective for cardiovascular disease treatment strategies. [Extracted from the article]

A retrospective cohort study examined 503 patients who underwent ventricular tachycardia (VT) ablation. The study identified 12 patients who experienced a lack of efficacy with various medications, including amiodarone, dobutamine, flecainide, lidocaine, mexiletine, procainamide, quinidine, and sotalol. One patient, a 70-year-old woman, had recurrent VT and received dobutamine infusion, but her condition did not improve. She underwent VT ablation but experienced complications and ultimately died from heart failure. The remaining 11 patients also had a history of VT and received different combinations of medications, but their conditions did not improve either. They underwent various procedures and received additional treatments, but all 11 patients died from recurrent VT. [Extracted from the article]

The article reports that a patent has been issued for a concentrated liquid formulation of furosemide, which includes details on its composition and potential benefits for subcutaneous administration. It also discusses the formulation's pH and osmolarity adjustments, the use of auto-injection devices, and the impact on patient compliance and treatment efficacy.

The article explores the mechanisms behind cardiac autonomic dysfunction in cirrhotic rats. Topics discussed include the impact of cirrhosis on cardiac sympathetic and vagal activities, changes in neuronal excitability and ion channel regulation, and potential implications for understanding cirrhosis-induced cardiac autonomic dysfunction.

A new study from Government Medical College in Maharashtra, India, explores the morphology of the cervicothoracic ganglion (stellate ganglion) and its relationship with adjacent structures. The study used both cadaveric and ultrasonographic methods to examine the ganglion. The researchers identified three distinct morphologies of the ganglion and found that the right ganglion was longer than the left. Ultrasonographic guidance may improve the safety and efficacy of stellate ganglion block procedures. The study provides valuable insights for the treatment of cardiac arrhythmias and reflex sympathetic dystrophy. [Extracted from the article]

A 47-year-old woman with a history of smoking developed a skin rash during treatment for refractory coronary angina. Despite trying multiple medications, including nicorandil, nifedipine, fasudil, and denopamine, her symptoms did not improve. She also experienced chest pain and seizures, which were partially alleviated with nitroglycerin and nicorandil. Various treatments were attempted, including stellate ganglion block and laser irradiation, but none provided significant relief. Ultimately, the woman received an implantable cardioverter-defibrillator (ICD) and underwent stent placement, which successfully resolved her symptoms for five years. [Extracted from the article]

A 59-year-old man with lymphocytic myocarditis was treated with methylprednisolone and mycophenolate mofetil. Despite receiving these medications, he did not respond well and experienced elevated troponin levels, ST-segment elevation, cardiac electrical storm, ventricular tachycardia, and haemodynamic instability. Additional treatments, including procainamide, esmolol, amiodarone, propofol, and veno-arterial extracorporeal membrane oxygenation, were administered, but the patient continued to have episodes of ventricular tachycardia and severe ventricular dysfunction. Ultimately, he was awaiting a cardiac transplant. [Extracted from the article]

A recent study conducted at Cairo University in Egypt compared the efficacy of stellate ganglion (SG) destruction with alcohol versus thermal ablation for managing chronic post-mastectomy pain. The study involved female patients who had undergone breast cancer surgery and experienced moderate to severe pain for more than 6 months. The results showed that SG destruction with alcohol was more effective in reducing pain scores and decreasing the consumption of pain medications compared to thermal ablation. The study suggests that SG destruction with alcohol may be a promising approach for managing postoperative pain in breast cancer patients. However, the study had limitations in terms of sample size and follow-up period. [Extracted from the article]

A patent has been issued for systems and methods for trans-esophageal sympathetic ganglion recruitment. The patent, assigned to Lungpacer Medical Inc., describes a method of treating brain injury by positioning a catheter with electrodes in the esophagus near sympathetic ganglia and recruiting the ganglia through electrical signals. The system includes sensors for monitoring physiological parameters and a controller to adjust the electrical signals based on the monitoring. The invention aims to prevent over-activation of the sympathetic system, which can lead to complications such as cardiac arrhythmias and neurogenic pulmonary edema. [Extracted from the article]

A 65-year-old woman experienced temporary weakness in her quadriceps while being treated with lidocaine for hip pain. She had previously received treatment for lumbar spinal stenosis, postherpetic neuralgia, and bilateral hip joint osteoarthritis. After receiving an injection of lidocaine, the woman's pain improved and has not returned after six months. The only side effect noted was the temporary weakness in her quadriceps. [Extracted from the article]

Researchers at the University of Texas Health Science Center in Houston have conducted a study on the safety and effectiveness of stellate ganglion cryoablation in treating complex regional pain syndrome (CRPS). The study involved eight patients diagnosed with CRPS who underwent the procedure. The researchers found that stellate ganglion cryoablation was a feasible, safe, and minimally invasive treatment option for select patients with CRPS. The study also introduced a novel CRPS scoring system called the Budapest score to assess symptom severity. [Extracted from the article]

A recent study conducted by researchers at Oregon Health & Science University (OHSU) explores the effects of ischemia-reperfusion myocardial infarction (MI) on stellate ganglion (SG) neurons in the heart. The study found that MI resulted in structural changes in cardiac-projecting left SG neurons, including smaller cell bodies and shorter dendritic trees. These changes may contribute to increased sympathetic activity after MI. The research provides valuable insights into the impact of MI on the sympathetic innervation of the heart and could potentially inform the development of new treatments for heart disease. [Extracted from the article]

In some embodiments, the one or more desired nerves of the stellate ganglion or the autonomic tissue area peripheral to the stellate ganglion comprise one or more desired nerves of the stellate ganglion. " "In some embodiments, navigating the treatment apparatus to the stellate ganglion comprises inserting the needle of the treatment apparatus percutaneously to one or more nerves of the stellate ganglion area. In other embodiments, the one or more desired nerves of the stellate ganglion or the autonomic tissue area peripheral to the stellate ganglion comprise one or more desired nerves of the autonomic tissue area peripheral to the stellate ganglion. For example, in instances that surgical stellate ganglion blockade was not feasible, temporary percutaneous stellate ganglion blockade has been shown to be an effective therapy for an adult patient with drug-refractory VT and VF. [Extracted from the article]

The one or more desired nerves of the stellate ganglion or the autonomic tissue area peripheral to the stellate ganglion can include one or more desired nerves of the autonomic tissue area peripheral to the stellate ganglion. The one or more desired nerves of the stellate ganglion or the autonomic tissue area peripheral to the stellate ganglion can include one or more desired nerves of the stellate ganglion. The one or more desired nerves of the stellate ganglion or the autonomic tissue area peripheral to the stellate ganglion can include one or more desired nerves of the autonomic tissue area peripheral to the stellate ganglion. The method of claim 24, wherein the one or more desired nerves of the stellate ganglion or the autonomic tissue area peripheral to the stellate ganglion comprise one or more desired nerves of a paravertebral chain. [Extracted from the article]

According to the news reporters, the research concluded: "SG recording and stimulation is feasible and may have value to elicit VA and understand neural mechanisms of VA in the electrophysiology laboratory." Keywords: Houston; State:Texas; United States; North and Central America; Arrhythmia; Cardiology; Health and Medicine; Pharmacology; Therapy EN Houston State:Texas United States North and Central America Arrhythmia Cardiology Health and Medicine Pharmacology Therapy 980 980 1 09/19/23 20230922 NES 230922 2023 SEP 18 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Data detailed on Arrhythmia have been presented. For more information on this research see: Stellate Ganglion Instrumentation for Pharmacological Blockade, Nerve Recording, and Stimulation In Patients With Ventricular Arrhythmias: Preliminary Experience. [Extracted from the article]

For more information on this research see: Phrenic nerve block combined with stellate ganglion block for postoperative intractable hiccups: a case report. Keywords: Health and Medicine EN Health and Medicine 7325 7325 1 09/19/23 20230922 NES 230922 2023 SEP 22 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on agriculture have been published. [Extracted from the article]

Autonomic Nervous System Diseases and Conditions, Complex Regional Pain Syndromes, Health and Medicine, Musculoskeletal Diseases and Conditions, Nervous System Diseases and Conditions, Neurology, Neuromuscular Diseases and Conditions, Pain Syndromes, Peripheral Nervous System Diseases and Conditions Keywords: Autonomic Nervous System Diseases and Conditions; Complex Regional Pain Syndromes; Health and Medicine; Musculoskeletal Diseases and Conditions; Nervous System Diseases and Conditions; Neurology; Neuromuscular Diseases and Conditions; Pain Syndromes; Peripheral Nervous System Diseases and Conditions EN Autonomic Nervous System Diseases and Conditions Complex Regional Pain Syndromes Health and Medicine Musculoskeletal Diseases and Conditions Nervous System Diseases and Conditions Neurology Neuromuscular Diseases and Conditions Pain Syndromes Peripheral Nervous System Diseases and Conditions 1519 1519 1 08/28/23 20230901 NES 230901 2023 AUG 28 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- New research on complex regional pain syndromes is the subject of a new report. [Extracted from the article]

For more information on this research see: Red Blood Cell Membrane-camouflaged Poly(Lactic-co-glycolic Acid) Microparticles As a Potential Controlled Release Drug Delivery System for Local Stellate Ganglion Microinjection. Keywords: Omaha; State:Nebraska; United States; North and Central America; Blood Cells; Cell Membrane; Cell Research; Cellular Structures; Controlled Release; Drug Delivery; Drug Delivery Systems; Drugs and Therapies; Health and Medicine; Inflammation; Microinjections EN Omaha State:Nebraska United States North and Central America Blood Cells Cell Membrane Cell Research Cellular Structures Controlled Release Drug Delivery Drug Delivery Systems Drugs and Therapies Health and Medicine Inflammation Microinjections 391 391 1 05/15/23 20230516 NES 230516 2023 MAY 18 (NewsRx) -- By a News Reporter-Staff News Editor at Hematology Week -- A new study on Drugs and Therapies - Drug Delivery Systems is now available. [Extracted from the article]

Heart rate (HR), blood pressure (BP), and cardiac output (CO) were measured before, during, and after stimulation. Keywords: Rochester; State:Minnesota; United States; North and Central America; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular Physiological Processes; Consciousness Disorders; Health and Medicine; Heart Rate; Hemodynamics; Nervous System Diseases and Conditions; Neurobehavioral Manifestations; Neurologic Diseases and Conditions; Neurologic Manifestations; Syncope; Unconsciousness EN Rochester State:Minnesota United States North and Central America Blood Pressure Cardiovascular Physiological Phenomena Cardiovascular Physiological Processes Consciousness Disorders Health and Medicine Heart Rate Hemodynamics Nervous System Diseases and Conditions Neurobehavioral Manifestations Neurologic Diseases and Conditions Neurologic Manifestations Syncope Unconsciousness 298 298 1 04/17/23 20230421 NES 230421 2023 APR 17 (NewsRx) -- By a News Reporter-Staff News Editor at Hematology Week -- New research on Neurologic Diseases and Conditions - Syncope is the subject of a report. [Extracted from the article]

Keywords: Tokyo; Japan; Asia; DNA Virus Infections; DNA Viruses; Health and Medicine; Herpes Zoster; Herpes Zoster Ophthalmicus; Herpes Zoster Virus; Herpesviridae Infections; Herpesvirus; Herpesvirus Diseases and Conditions; Inflammation; Therapy; Viral Eye Infections; Virology EN Tokyo Japan Asia DNA Virus Infections DNA Viruses Health and Medicine Herpes Zoster Herpes Zoster Ophthalmicus Herpes Zoster Virus Herpesviridae Infections Herpesvirus Herpesvirus Diseases and Conditions Inflammation Therapy Viral Eye Infections Virology 1227 1227 1 04/03/23 20230407 NES 230407 2023 APR 7 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Current study results on Herpesvirus Diseases and Conditions - Herpes Zoster Ophthalmicus have been published. For more information on this research see: Successful Treatment of Herpes Zoster Ophthalmicus Complicated By Intense Orbital Inflammation Using Laser Irradiation Over the Stellate Ganglion. [Extracted from the article]