Search

This study takes an intersectional position when examining K-12th grade students’ school-based discipline experiences in minoritized communities. We build on the intersectional view of minoritized racial and gender experiences by adding to additional dimensions of marginalized identity to predictive models of disciplinary absences. Using negative binomial regression, we model disciplinary absences by gender, racial identity, poverty, and primary language, adding interaction terms to explicitly account for cumulative moderating effects of having more than one marginalized identity. Participants included 8,495 kindergarten through 12th grade students enrolled in the 21st Century Community Learning Center after school program during the 2016–2017 school year. Analyses suggested differences in disciplinary absences across racial identities and qualification of free or reduced lunch. Results also indicated that when controlling for covariates, being male predicted more disciplinary absences than being female among White students. However, this effect was not evident among male participants whose primary language was English. These findings highlight the need for culturally responsive and affirming programming to further improve equitable access to positive outcomes.

This study took a family systems perspective and tested spillover theory to examine the transmission of stress from parents to children during COVID-19. Using a longitudinal design with a 1-year interval, we tested the association between parent perceived stress and perceived child stress, and the sequential mediating effects of poor family functioning and parent–child closeness. The data comprised 134 parents residing in the US who were assessed from the initial first peak of COVID-19 infections in 2020 to 2021, 1 year later. Results indicated that when controlling for covariates, there was a significant association between parent perceived stress and perceived child stress. What is more, poor family functioning and parent–child closeness fully mediated the former link in sequence. These findings highlighted the need for improving family relationship quality when providing interventions that target families suffering in stressful contexts.

Abstract: This paper presents a set of topical and pedagogical considerations for instructors teaching material on sensitive topics with either the primary or secondary aim of addressing prevention. Prevention can be approached as an effort to create changes in an individual’s attitudes/beliefs, knowledge, and behavior. Following this framework, classroom content that challenges students’ perceptions, preconceived notions, and attitudes can be seen as preventive in nature. Preparing students to work through the same layers of complexity that thoroughly trained and experienced researchers and practitioners struggle with requires particular attention to the classroom environment.

Objective: To describe the approach and outcomes from two cancer centres in Southern and Northern Europe during the first wave of coronavirus disease 2019 (COVID-19) of patients with head and neck cancer (HNC).Methods: Data collection was performed on a retrospective cohort of patients surgically treated for primary HNC between March and May 2020, using data from two tertiary hospitals: the European Institute of Oncology (Milan) and Guy’s & St Thomas’ NHS Foundation Trust (London).Results: We included 77 patients with HNC. More patients with COVID-19 were taking angiotensin-converting enzyme (ACE) inhibitors and had Clavien-Dindo Classification grade I compared to negative patients, respectively (60% vs 22% [p= 0.058] and 40% vs 8% [p= 0.025]). Multivariate logistic regression analyses confirmed our data (p= 0.05 and 0.03, respectively). Sex and age were statistically significantly different (p= 0.05 and <0.001 respectively), showing more male patients (75% vs 53.66%, respectively) and more elderly patients in Italy than in the United Kingdom (patients aged >63 years: 69.44% vs 29.27%).Conclusions: This study presents a large cohort of patients with HNC with nasopharyngeal swab during the first peak of the COVID-19 pandemic in Europe. Patients with HNC with COVID-19 appeared more likely to develop postsurgical complications and to be taking ACE inhibitors. The preventive measures adopted guaranteed the continuation of therapeutic surgical intervention.

The provision of access to materials in special collections intersects the fields of cataloging and special collections librarianship, sharing characteristics and challenges with both. In order to reveal the changing [...]

While many catalogers are using the Web to find the information they need to perform authority work quickly and accurately, the full potential of the Web to assist catalogers in [...]

IMPORTANCE: Whether the severity and mortality of COVID-19 in patients with cancer have improved in terms of disease management and capacity is yet to be defined. OBJECTIVE: To test whether severity and mortality from COVID-19 among patients with cancer have improved during the course of the pandemic. DESIGN, SETTING, AND PARTICIPANTS: OnCovid is a European registry that collects data on consecutive patients with solid or hematologic cancer and COVID-19. This multicenter case series study included real-world data from 35 institutions across 6 countries (UK, Italy, Spain, France, Belgium, and Germany). This update included patients diagnosed between February 27, 2020, and February, 14, 2021. Inclusion criteria were confirmed diagnosis of SARS-CoV-2 infection and a history of solid or hematologic cancer. EXPOSURES: SARS-CoV-2 infection. MAIN OUTCOMES AND MEASURES: Deaths were differentiated at 14 days and 3 months as the 2 landmark end points. Patient characteristics and outcomes were compared by stratifying patients across 5 phases (February to March 2020, April to June 2020, July to September 2020, October to December 2020, and January to February 2021) and across 2 major outbreaks (February to June 2020 and July 2020 to February 2021). RESULTS: At data cutoff, 2795 consecutive patients were included, with 2634 patients eligible for analysis (median [IQR] age, 68 [18-77] years ; 52.8% men). Eligible patients demonstrated significant time-dependent improvement in 14-day case-fatality rate (CFR) with estimates of 29.8% (95% CI, 0.26-0.33) for February to March 2020; 20.3% (95% CI, 0.17-0.23) for April to June 2020; 12.5% (95% CI, 0.06-22.90) for July to September 2020; 17.2% (95% CI, 0.15-0.21) for October to December 2020; and 14.5% (95% CI, 0.09-0.21) for January to February 2021 (all P &lt; .001) across the predefined phases. Compared with the second major outbreak, patients diagnosed in the first outbreak were more likely to be 65 years or older (974 of 1626 [60.3%] vs 564 of 1008 [56.1%]; P = .03), have at least 2 comorbidities (793 of 1626 [48.8%] vs 427 of 1008 [42.4%]; P = .001), and have advanced tumors (708 of 1626 [46.4%] vs 536 of 1008 [56.1%]; P &lt; .001). Complications of COVID-19 were more likely to be seen (738 of 1626 [45.4%] vs 342 of 1008 [33.9%]; P &lt; .001) and require hospitalization (969 of 1626 [59.8%] vs 418 of 1008 [42.1%]; P &lt; .001) and anti–COVID-19 therapy (1004 of 1626 [61.7%] vs 501 of 1008 [49.7%]; P &lt; .001) during the first major outbreak. The 14-day CFRs for the first and second major outbreaks were 25.6% (95% CI, 0.23-0.28) vs 16.2% (95% CI, 0.13-0.19; P &lt; .001), respectively. After adjusting for country, sex, age, comorbidities, tumor stage and status, anti–COVID-19 and anticancer therapy, and COVID-19 complications, patients diagnosed in the first outbreak had an increased risk of death at 14 days (hazard ratio [HR], 1.85; 95% CI, 1.47-2.32) and 3 months (HR, 1.28; 95% CI, 1.08-1.51) compared with those diagnosed in the second outbreak. CONCLUSIONS AND RELEVANCE: The findings of this registry-based study suggest that mortality in patients with cancer diagnosed with COVID-19 has improved in Europe; this improvement may be associated with earlier diagnosis, improved management, and dynamic changes in community transmission over time.

BackgroundThere is increasing evidence for the use of exercise in cancer patients and data supporting enhanced tumour volume reduction following chemotherapy in animal models. To date, there is no reported histopathological evidence of a similar oncological benefit in oesophageal cancer.MethodsA prospective non-randomised trial compared a structured prehabilitation exercise intervention during neoadjuvant chemotherapy and surgery versus conventional best-practice for oesophageal cancer patients. Biochemical and body composition analyses were performed at multiple time points. Outcome measures included radiological and pathological markers of disease regression. Logistic regression calculated ORs with 95% CI for the likelihood of pathological response adjusting for chemotherapy regimen and chemotherapy delivery.ResultsComparison of the Intervention (n=21) and Control (n=19) groups indicated the Intervention group had higher rates of tumour regression (Mandard TRG 1–3 Intervention n=15/20 (75%) vs Control n=7/19 (36.8%) p=0.025) including adjusted analyses (OR 6.57; 95% CI 1.52 to 28.30). Combined tumour and node downstaging (Intervention n=9 (42.9%) vs Control n=3 (15.8%) p=0.089) and Fat Free Mass index were also improved (Intervention 17.8 vs 18.7 kg/m2; Control 16.3 vs 14.7 kg/m2, p=0.026). Differences in markers of immunity (CD-3 and CD-8) and inflammation (IL-6, VEGF, INF-y, TNFa, MCP-1 and EGF) were observed.ConclusionThe results suggest improved tumour regression and downstaging in the exercise intervention group and should prompt larger studies on this topic.Trial registration numberNCT03626610.

Background We sought to understand the association between heavy alcohol and frequent drug use and non-adherence to recommended social distancing and personal hygiene guidelines for preventing the spread of COVID-19 early in the US pandemic.Methods A survey was offered on the crowdsourcing platform, Amazon Mechanical Turk (MTurk) during April 2020 (the early days of strict, social distancing restrictions). The study included 1,521 adults ages 18 years and older who resided in the US and were enrolled as MTurk workers, i.e., workers who are qualified by Amazon to complete a range of human interaction tasks, including surveys through the MTurk worker platform. Main predictors included measures of heavy drinking, marijuana, and polysubstance use. The dependent measures were measures of social distancing and personal hygiene, based on guidelines recommended at the time of the survey by the US Centers for Disease Control to prevent the spread of COVID-19.Results We found consistent negative associations between heavy drinking and drug use and adherence to social distancing and personal hygiene. Additionally, three control variables, age, gender, and race/ethnicity, were significant correlates of adherence to these measures.Conclusions The findings here are consistent with previous research exploring links between substance use and other adverse health behaviors. Further, the negative association between heavy drinking (five or more drinks in one sitting) and adherence underscore the public health risks entailed with the unrestricted reopening of public drinking establishments.

The complexity of bladder cancer diagnosis and staging results in delays in definitive treatment of muscle-invasive bladder cancer by radical cystectomy.

The article focuses on a designing of new free app that can bring the power of earthquake to life on smartphone. It mentions the role of SOS Explorer Mobile app that comes from a long line of visualization tools from the Global Systems Division (GSD) and installed in more museums, science centers, universities, and other educational facilities.

Adherence to and retention in Medication Treatment for Opioid Use Disorders (MOUD) persist. We systematically reviewed trends of USA MOUD adherence, retention, and barriers from 2011–2021. Primary outcomes were adherence to and retention in MOUD, abstinence, adverse events, and treatment barriers. Effects of inverse variance random meta-analyses were examined using proportions and 95% CIs. 28 studies (102,318 patients), 78.1% male. Adherence was 56% across all studies, highest for methadone (73%). Retention by study design was heterogeneous: case series (57%), cohorts (47%), and RCTs (70%). The most common barriers were younger age, comorbid diagnoses, daily attendance, no insurance, and transportation. Abstinence was 72%, and adverse events was 5%. There was high heterogeneity in MOUD across drug types and study designs. Our findings extend the knowledge base of MOUD treatment to describe barriers that underpin the focus on retention in care above adherence given its focus to harm reduction principles.

In the adult population chronic pain can lead to loss of productivity and earning potential, and decreased quality of life. There are distinct groups with increased vulnerability for the emergence of chronic pain. These groups may be defined by developmental status and/or life circumstances. Within the pediatric, geriatric, and drug abuser populations, chronic pain represents a significant health issue. This article focuses on known anatomic, physiologic, and genetic mechanisms underlying chronic pain in these populations, and highlights the need for a multimodal approach from multiple health care professionals for management of chronic pain in those with the most risk.

The article discusses participation of children in sociodramatic play.

The authors offer advice to other librarians who are beginning research projects, based on their own experiences researching electronic book (e-book) usage at the New York University Abu Dhabi (NYUAD) Library. The authors conducted a use study in 2011 on the e-book reading habits and opinions of students, staff, and faculty at the university. They offer advice for other researchers such as creating clear research goals, getting support from colleagues, and learning about research software. The authors mention the article "Why Aren't E-Books Gaining More Ground in Academic Libraries" by Robert Slater, web-based survey software Qualtrics, and the American Library Association (ALA).

The article presents a literature review that is focused on the responsibilities of educational leaders and how they can effectively accomplish their tasks through collaboration. It is noted that some tasks are better suited for certain people because of their personality type. Suggestions are presented regarding how principals can begin to think about the tasks that they enjoy and those that they do not like to complete.

Bladder cancer (BC) is the 10thmost common malignancy worldwide and the patient experience is found to be worse than that for patients diagnosed with other cancer types. We aimed to develop a wellbeing intervention to help improve the bladder cancer patient experience by ameliorating their health-related Quality of Life (HRQoL). We followed the 3 phases of the modified Medical Research Council (MRC) Framework for development of complex interventions. Following a systematic review of the literature on mental, sexual, and physical wellbeing, we conducted discussion groups with patients and healthcare professionals on these 3 themes. A consultation phase was then conducted with all relevant stakeholders to co-design a wellbeing intervention as part of a feasibility study. A pragmatic wellbeing feasibility trial was designed based on the hypothesis that a wellbeing program will increase patient awareness and attendance to services available to them and will better support their needs to improve HRQoL. The primary feasibility endpoints are patient attendance to the services offered and changes in HRQoL. The principle of patient centered care has strengthened the commitment to provide a holistic approach to support BC patients. In this study, we developed a wellbeing intervention in collaboration with patients and healthcare professionals to meet an unmet need in terms of the BC patient experience.

The article offers some insights into the benefits of using neutral language based on personality type theory in helping teachers and administrators talk about the different ways people teach and learn. Personality type theory describes normal differences in how people are energized, take in information, make decisions and approach work and life.

Offers advice to librarians on how to digitize special collections based on the experience of the Texas A&M library. Construction of a database of photographs; Training and supervising the summary writing; Scanning and Web phases.

Scholars working in the fields of medieval history and cultural history have recognized that understanding the cataloging and accessioning of books is central to understanding the transmission of ideas. This view should come as no surprise to catalogers themselves, who daily struggle with the problem of providing intellectual, and sometimes physical, access to texts and information. Unfortunately, general histories of libraries and even the library literature seem content to sketch out a chronological development of cataloging in line with the nineteenth and twentieth century view of library development, from a simple list to complex intellectual systems. In truth, however, those individuals responsible for cataloging books in medieval libraries faced many of the same challenges as catalogers today: how to organize information, how to serve local needs, and how to provide access to individual works within larger bibliographic formats. This article will summarize recent scholarship in the history of the book that relates to library cataloging, as well as providing parallels to the cooperative library environment of today.

COVID-19 has forced governments to make drastic changes to healthcare systems. To start making informed decisions about cancer care, we need to understand the scale of COVID-19 infection. Therefore, we introduced swab testing for patients visiting Guy’s Cancer Centre. Our Centre is one of the largest UK Cancer Centers at the epicenter of the UK COVID-19 epidemic. The first COVID-19 positive cancer patient was reported on 29 February 2020. We analyzed data from 7-15 May 2020 for COVID-19 tests in our cancer patients. 2,647 patients attended for outpatient, chemotherapy, or radiotherapy appointments. 654 were swabbed for COVID-19 (25%). Of those tested, 9 were positive for COVID-19 (1.38%) of which 7 were asymptomatic. Cancer service providers will need to understand their local cancer population prevalence. The absolute priority is that cancer patients have the confidence to attend hospitals and be reassured that they will be treated in a COVID-19 managed environment.

Features the Cushing Memorial Library at Texas A&M University in College Station. Renovation of the building; Building history; Collections; Services in the renovated building.

Introduction:Gradual introduction of non-vitamin K antagonist oral anticoagulants (NOACs) provided new treatment options for stroke prevention of atrial fibrillation (SPAF).Hypothesis:To characterize the treatment pathways for SPAF in a real world setting across a network of diverse populations and databases.Methods:This retrospective cohort study used multiple data sources (Belgium, France, Germany, UK and US) and analysed using an adaptation of Observational Health Data Sciences and Informatics (OHDSI) Treatment Pathway Tool. Patients aged ?18 years with a diagnosis of AF and at least one prescription of oral anticoagulants (OACs) were included from 2010 through 2017. Treatment share of OACs at index year vs. end year of follow-up was presented for patients with adequate follow-up. Sequence of treatment changes presented as sunburst graphs.Results:Almost 3.3 million patients were analysed across data sources from five countries in which the majority of patients were aged 65 and over. Based on the medical history, patients in the US were more comorbid than the other countries, in particular with cardiovascular comorbidities. UK showed a slower uptake of NOACs compared to other countries like the US, which had introduced NOACs for around 50% of the patients by 2011. France, Belgium and Germany introduced NOACs at a moderate rate with around 40% of patients receiving NOACs by 2012. Apixaban and rivaroxaban had the highest treatment shares. Compared to other countries use of Dabigatran was minimal in UK. Compared to the index year, 20-50% of patients stopped their OAC treatment in the end year of follow-up in every country except UK with ?15% (Fig 1).Conclusions:This international observational study using multiple data sources has shown the clinical landscape of SPAF treatment since 2010. The treatment discontinuation was highest in the US (40-50%) and lowest in the UK. Majority of patients currently receive apixaban and rivaroxaban as the first line of treatment.