Author: "Rodenburg, Wendy" / Publication Type: Magazines - Searchworks@Jio Institute Digital Library Search Results

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Author: Bruning, Oskar, Yuan, Xiaolian, Rodenburg, Wendy, Bruins, Wendy, van Oostrom, Conny T., Rauwerda, Han, Wittink, Floyd R.A., Jonker, Martijs J., de Vries, Annemieke, and Breit, Timo M.
Abstract: Reanalysis of our UV study of p53-mutant mouse embryonic fibroblasts revealed an intriguing orchestration of massive transcriptome responses. However, close scrutiny of the data uncovered an affected mRNA/rRNA ratio, effectively inhibiting valid data analysis. UV-dose range-finding showed low-dose UV specific- and high-dose stress-related responses, which represent a plea for UV dose range-finding in experimental design.
Published: 2010
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