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Presents letters to the editor to comment on various articles in previous issues. Cecil Smith's comments on the concert appearances of Kirsten Flagstad; Bernard Posner's "What'll We Use of Dough?" in the March 24, 1947 issue on the income of an average American family for 1946; Henry Wallace in Great Britain; Shirley O'Hara's review of the film "My Favorite Brunette," by Edward Robert Isaacs in the April 7, 1947 issue; Editorial in the March 24, 1947 issue regarding the exclusion of Negro reporters from the congressional press galleries.

EVE ROBINSON Fascinated by fashion while growing up in New York, Robinson held holiday jobs at Seventeen magazine and Estee Lauder during her teenage years. Her mother, however, knew she […]

* Before anything else, ask these questions: How much do you use the room? Do you entertain or eat there? Does the space need to be child- or pet-friendly? The […]

The article presents reflections from New Zealand composers on staying in their country and living overseas. Eve de Castro-Robinson identifies the dilemma of student composers, and cites lifestyle reasons among the factors which influence the decision to head overseas. Gillian Whitehead discusses settling in Great Britain, her employment in Sydney, New South Wales, and her return to New Zealand.

CD4 T cells recognize peptides bound to major histocompatibility complex (MHC) class II molecules. Most MHC class II molecules have four binding pockets occupied by amino acids 1, 4, 6, and 9 of the minimal peptide epitope, while the residues at positions 2, 3, 5, 7, and 8 are available to interact with the T cell receptor (TCR). In addition MHC class II bound peptides have flanking residues situated outside of this peptide core. Here we demonstrate that the flanking residues of the conalbumin peptide bound to I-A^k have no effect on recognition by the D10 TCR. To study therole of peptide flanks for recognition by a second TCR, we determined the MHC and TCR contacting amino acids of the I-A^b bound Eα peptide. The Eα peptide is shown to bind I-A^b using four alanines as anchor residues. TCR recognition of Eα peptides with altered flanking residues again suggested that, in general, no specific interactions occurred with the peptide flanks. However, using an HLA-DM-mediated technique to measure peptide binding to MHC class II molecules, we found that the peptide flanking residues contribute substantially to MHC binding.

The measles-specific antibody responses of seronegative adolescents and young adults were evaluated after revaccination. Of 1650 previously vaccinated healthy volunteers between the ages of 10 and 30 years, 4.4 were found to be seronegative for measles antibodies and 9.9 had equivocal titers. Seronegative volunteers were revaccinated to measles and followed serially for development of measles-specific IgG. Of 43 subjects followed for at least 1 year, only 58 developed and maintained positive antibody titers; 12 never developed positive titers and 30 initially developed titers that fell below positive levels within 1 year. The peak titers achieved by those subjects who responded transiently were lower than those achieved by subjects who developed sustained responses. Thus even after the recommended two dose schedule of the current measles vaccine, some adolescents and young adults lack protective titers of measles-specific antibody.

The article focuses on Kiwi composer Jack Body, who was diagnosed with terminal cancer. Topics discussed include the entrepreneurial skill of Body unique in the music of New Zealand, the Asian-Pacific festivals, and his interest in the connection between creativity and sexuality. Also mentioned his long-term project titled "Songs and Dances of Death & Desire: In Memoriam Carmen Rupe," an orchestral tribute to the life and personality of the late Maori drag queen and dancer.

The article offers information on the events comprising the International Society for Contemporary Music (ISCM) World New Music Days festival. The impact of New Zealand's membership to ISCM is discussed. A four-hour process of music and culinary heritage is dubbed Procession. A concert by the Lithuanian National Symphony Orchestra included old and new compositions.

ABSTRACTOvarian cancer accounts for most deaths from gynecologic malignancies. Although more than 80% of patients respond to first-line standard of care, most of these responders present with recurrence and eventually succumb to carcinomatosis and chemotherapy-resistant disease. To improve patient survival, new modalities must, therefore, target or prevent recurrent disease. Here we describe for the first time a novel syngeneic mouse model of recurrent high-grade serous ovarian cancer (HGSOC), which allows immunotherapeutic interventions in a time course relevant to human carcinomatosis and disease course. Using this model, we demonstrate the efficacy of Transimmunization (TI), a dendritic cell (DC) vaccination strategy that uses autologous and physiologically derived DC loaded with autologous whole tumor antigens. TI has been proven successful in the treatment of human cutaneous T cell lymphoma and we report for the first time its in vivoefficacy against an intra-peritoneal solid tumor. Given as a single therapy, TI is able to elicit an effective anti-tumor immune response and inhibit immune-suppressive crosstalks with sufficient power to curtail tumor progression and establishment of carcinomatosis and recurrent disease. Specifically, TI is able to inhibit the expansion of tumor-associated macrophages as well as myeloid-derived suppressive cells consequently restoring T cell immune-surveillance. These results demonstrate the possible value of TI in the management of ovarian cancer and other intra-peritoneal tumors.

The article evaluates several paints for guest rooms including soft duckling from Valspar Corp., Himalayan Trek from Benjamin Moore & Co., and Confidential from Pratt & Lambert.

The article offers several insights regarding the use of color paints at home office including Olivewood 30YY 36/094, Heritage Red PM-18 and Blue Gray 91.

Two letters to the editor are presented in response to articles in previous issues including "Trivial Pursuits," related to celebrities in the July 2006 issue and "School for Scandal" in the June 2006 issue.