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A recent study analyzed 10,832 prokaryotic genomes to investigate the presence of pseudogenes in plasmid genomes. Pseudogenes are non-functional genes that can provide insights into evolutionary processes. The study found that plasmid genomes have a higher density of pseudogenes compared to chromosomes, with many of these pseudogenes corresponding to deteriorated transposable elements. The analysis of enterobacterial plasmids revealed frequent gene non-functionalization events associated with the loss of plasmid self-transmissibility, leading to the emergence of non-mobilizable plasmid types. This research provides valuable insights into the evolution of plasmids and their impact on bacterial lifestyle. [Extracted from the article]

A recent study analyzed over 10,000 prokaryotic genomes to investigate the presence of pseudogenes in plasmid genomes. Pseudogenes are non-functional genes that can provide insights into evolutionary processes. The study found that plasmid genomes have a higher density of pseudogenes compared to chromosomes, with many of these pseudogenes corresponding to deteriorated transposable elements. The analysis of enterobacterial plasmids revealed frequent gene non-functionalization events associated with the loss of plasmid self-transmissibility, leading to the emergence of non-mobilizable plasmid types. This research sheds light on the evolution of domesticated plasmids and provides insights into past transitions in plasmid mobility. [Extracted from the article]

Keywords for this news article include: National Institute of Genomic Medicine, Mexico City, Mexico, North and Central America, Cancer, Oncology, Health and Medicine. Keywords: Cancer; Health and Medicine; Oncology EN Cancer Health and Medicine Oncology 1364 1364 1 09/11/23 20230912 NES 230912 2023 SEP 12 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- Researchers detail new data in cancer. [Extracted from the article]

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http://discovermagazine.com/2003/sep/breakgene

Researchers from The University of Texas MD Anderson Cancer Center in Houston have found that pseudogenes alone and in combination with other clinical and molecular markers may help define prognostic subgroups in seven types of cancer. The findings also suggest new areas of research into the mechanistic roles pseudogenes play in cancer., (©2014 American Association for Cancer Research.)

The article focuses on professor Yoav Gilad who conducted a research on gene regulation. It informs that Gilad met geneticist Doron Lancet who offered him a lab rotation and Gilad accepted it and in Lancet's lab he found twice number of genes with lost the ability to code proteins known as pseudogenes for olfactory receptors in humans. It states that using high-throughput multispecies DNA arrays Gilad identified sets of genes in primate species whose expression is derived by natural selection.