1. Supplementation With Plant Sterols and Fish Oil May Improve Lipid Profile in Mildly Hypercholesterolemic Subjects.
- Abstract
In randomized, double-blind, controlled, 2x2 factorial study involving 200 mildly hypercholesterolemic Indian adults, aged 35-55 years, results indicate that supplementation with plant sterols and fish oil may exert significant beneficial effects on lipid profile. The subjects were randomized to 1 of 4 groups for a period of 4 weeks: (1) control yoghurt drink and control capsules, (2) control yoghurt drink and fish oil capsules (2 g/day), (3) plant sterol-enriched (2 g/d) yoghurt drink and control capsules, or (4) plant sterol-enriched yoghurt drink and fish oil capsules. At intervention end, a 4.5% reduction in LDL-Cholesterol and a 15% reduction in TAG were observed in the plant sterol-supplemented group, compared with controls. Similarly, a 15% reduction in TAG and a 5.4% increase in HDL-Cholesterol were observed in the fish oil-supplemented group, compared with controls. Combined supplementation with plant sterols and fish oil was associated with a 15% reduction in TA G, compared with controls. Thus, the authors of this study conclude, "Once-a-day intake of 2 g plant sterols/d in a yoghurt drink, 2 g fish oil n-3 LC-PUFA/d in capsules, and their combination had beneficial effects on the lipid profile of mildly hypercholesterolaemic Indian adults. The potent hypotriacylglycerolaemic effect of plant sterols observed in the present study and this population warrants additional investigation." [ABSTRACT FROM AUTHOR] more...
- Published
- 2009