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Study objectives: We describe a series of patients with symptomatic, refractory malignant pleural effusion (MPE) and underlying trapped lung syndrome who underwent placement of a small-bore, flexible indwelling pleural catheter [...]

Grace W Pien, MD(*); Cathi Washam, RN; Mary Gant, RN and Daniel H Sterman, MD, Pulmonary, Allergy and Critical Care Division, Hospital of the University of Pennsylvania, Philadelphia, PA. PURPOSE: [...]

(Abstracted from Obstet Gynecol2019;134:667–676)Maternal sleep position has been associated with adverse pregnancy outcomes including fetal growth restriction and stillbirth. Despite prior data suggesting a relation between supine sleep position and adverse pregnancy outcomes, there remains uncertainty in regard to the validity of these findings, due to the potential for recall bias.

The goal of this study was to examine different paradigms for determining critical closing pressures (Pcrit). Methods of determining Pcrit were compared, including direct observation of occluded (no flow) breaths versus inferring Pcrit from extrapolated data, and Pcrit generated by aggregating pressure-flow data from multiple runs versus Pcrit averaged across individual pressure-flow runs. The relationship between Pcrit and obstructive sleep apnea (OSA) was examined.

Manual scoring of polysomnograms is a time-consuming and tedious process. To expedite the scoring of polysomnograms, several computerized algorithms for automated scoring have been developed. The overarching goal of this study was to determine the validity of the Somnolyzer system, an automated system for scoring polysomnograms.

This study aims to estimate the prevalence and predictors of moderatesevere poor sleep in relation to the final menstrual period (FMP) in midlife women.

To determine intersite agreement in respiratory event scoring of polysomnograms (PSGs) using different hypopnea definitions.

Manual scoring of polysomnograms (PSG) is labor intensive and has considerable variance between scorers. Automation of scoring could reduce cost and improve reproducibility. The purpose of this study was to compare a new automated scoring system (YST-Limited, Winnipeg, Canada) with computer-assisted manual scoring.

Explore the prevalence of sleep-related complaints across age groups, examining effects of sex, general health, and depressed mood.

This article reviews current data on pathophysiologic mechanisms by which sleep-disordered breathing during pregnancy may cause harm, and explores biological pathways for associated adverse maternal and fetal outcomes, especially pregnancy-induced hypertension and gestational diabetes.

To determine associations between menopausal status, reproductive hormone levels, menopausal symptoms, and poor sleep quality.

Although incident snoring is common in pregnant women and has been proposed as a potential risk factor for adverse maternal-fetal outcomes, the development of sleep-disordered breathing during pregnancy has not been prospectively described.

This paper reviews the topic of sleep disorders in pregnant women. We describe changes in sleep architecture and sleep pattern during pregnancy, discuss the impact of the physical and biochemical changes of pregnancy on sleep in pregnant women and examine whether maternal-fetal outcomes may be adversely affected in women with disordered sleep. The literature on common sleep disorders affecting pregnant women, including insomnia, sleep-disordered breathing and restless legs syndrome, is reviewed and recommendations are made for the management of these disorders during pregnancy.