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J Med Genet 2003;40:815-819 Background: A Y chromosomal role in prostate cancer has previously been suggested by both cytogenetic findings and patterns of Y chromosomal gene expression. We took advantage [...]

L’objectif de cette étude était d’évaluer l’incidence, les causes et les conséquences des pannes d’équipement dans un service de chirurgie laparoscopique endoscopique avancée de gros volume.

We have determined Y-chromosomal DNA haplotypes in 73 infertile European males carrying Y microdeletions and compared them with the haplotypes of 299 infertile males lacking microdeletions. Chromosomes were typed with a set of 11 binary Y markers, which identified 8 haplogroups in the sample. Haplogroup frequencies were compared between 3 microdeletion classes and the non-deleted infertile males. Deletions arise on many different haplotypic backgrounds. No statistically significant differences in frequency were seen, although the small number of AZFadeletions lay predominantly on one branch of the Y haplotype tree.

Forty Italian individuals with sperm counts in the range 20–130×106/ml were typed with eleven Y-specific binary markers. Five Y haplogroups (1, 2, 3, 9 and 21) were present in the sample. In Italy, in contrast to Denmark, sperm counts were similar in the different haplogroups.