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To validate the gene expression profile obtained from the previous microarray analysis and to further study the biological functions of these genes in endometrial cancer. From our previous study, we identified 621 differentially expressed genes in laser-captured microdissected endometrioid endometrial cancer as compared to normal endometrial cells. Among these genes, 146 were significantly up-regulated in endometrial cancer.

Genistein is known to influence reproductive system development through its binding affinity for estrogen receptors. The present study aimed to further explore the effect of Genistein on the development of the reproductive system of experimental rats.

Coital activity at term reportedly is associated with shorter gestation and less need to induce labor because of prolonged pregnancy, but such findings have not been consistently affirmed. In this randomized study, 108 women scheduled to have nonurgent induction of labor at term (37 weeks' gestation or later) were randomly assigned to be advised to have vaginal intercourse with the goal of hastening the onset of labor. They were told that intercourse late in pregnancy was safe and could promote the onset of labor. The 102 women in a control group were neither encouraged nor discouraged to have coitus. Labor was induced by amniotomy if the cervix was favorable and by vaginal dinoprostone if it was unfavorable. All participants kept a coital and orgasm diary and received standard obstetrical care.