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The article states that researchers from Poland have reported on four variants of a Citrobacter freundii cephalosporinase in a Proteus mirabilis clone. According to them, twenty-nine Proteus mirabilis isolates from 17 Polish hospitals were analyzed. The isolates were resistant to a variety of antimicrobials, and their patterns of resistance to betalactams resembled those of the constitutive class C cephalosporinase producers. They explained that beta-lactamases with a pI of similar to 9.0 were found in all of the isolates, and they were subsequently identified as four AmpC-type cephalosporinases, CW-4, -12, -14, and -15, of which the two last ones were novel enzyme variants. They published their study in the 2004 issue of the journal Antimicrobial Agents and Chemotherapy.

Reports on a study on the economic impact of meningococcal vaccine programs in Netherlands. Findings published in a 2004 issue of "Vaccine