200 results on '"Naggara ON"'
Search Results
2. Breaking the glass ceiling for Mechanical Thrombectomy access in France
- Author
-
Zhu, François, Kerleroux, Basile, Pruvo, Jean Pierre, Naggara, Olivier, Caroff, Jildaz, Berge, Jérôme, Alamowitch, Sonia, Desal, Hubert, and Boulouis, Grégoire
- Published
- 2024
- Full Text
- View/download PDF
3. Effects of weather conditions on endovascular treatment case volume for patients with ischemic stroke
- Author
-
Malka, David, Janot, Kevin, Pasi, Marco, Desilles, Jean-Philippe, Marnat, Gaultier, Sibon, Igor, Consoli, Arturo, Dargazanli, Cyril, Arquizan, Caroline, Gory, Benjamin, Richard, Sébastien, Naggara, Olivier, Clarençon, Frédéric, Rosso, Charlotte, Bourcier, Romain, Eker, Omer, Caroff, Jildaz, Lapergue, Bertrand, and Boulouis, Grégoire
- Abstract
Weather conditions have been shown to influence the occurrence of cardiovascular events. We tested the hypothesis that weather parameters may be associated with variations of case volume of endovascular treatment (EVT) for acute ischemic stroke.
- Published
- 2023
- Full Text
- View/download PDF
4. Diffusion-Weighted Imaging Lesion Reversal in Older Patients With Stroke Treated With Mechanical Thrombectomy
- Author
-
Scopelliti, Giuseppe, Benzakoun, Joseph, Ben Hassen, Wagih, Bretzner, Martin, Bricout, Nicolas, Puy, Laurent, Turc, Guillaume, Boulouis, Grégoire, Oppenheim, Catherine, Naggara, Olivier, Cordonnier, Charlotte, Henon, Hilde, and Pasi, Marco
- Published
- 2023
- Full Text
- View/download PDF
5. Malformaciones vasculares cerebrales en niños
- Author
-
Vergnaud, E., Terzi, E., Blauwblomme, T., Naggara, O., Boulouis, F.G., and Meyer, P.G.
- Abstract
Las malformaciones arteriovenosas (MAV) son anomalías congénitas que consisten en una conexión anormal entre arterias y venas cerebrales a través de neovasos. El 3-20% de las MAV se revelan en la infancia por una hemorragia cerebral, convulsiones o cefaleas, o en pruebas de imagen efectuadas por otro motivo en un paciente asintomático. Las malformaciones aneurismáticas de la vena de Galeno (MAVG) representan más del 80% de las MAV en niños menores de 2 años. Pueden tener consecuencias hemodinámicas sistémicas y cerebrales que varían en función de la importancia de la derivación arteriovenosa. El diagnóstico se efectúa en el recién nacido o el lactante de pocos meses, o en el período intrauterino. Las MAVG requieren un tratamiento multidisciplinario, que depende de la edad en el momento del diagnóstico y de la repercusión de la malformación. Las fístulas arteriovenosas piales se desarrollan sobre todo durante la infancia y la edad adulta, rara vez en el período intrauterino. También pueden tener consecuencias hemodinámicas sistémicas y cerebrales. A diferencia de las MAVG, el tratamiento endovascular debe efectuarse tan pronto como se establezca el diagnóstico. Las malformaciones de los senos durales rara vez tienen repercusiones sistémicas y dan lugar a manifestaciones clínicas relacionadas con un defecto del drenaje venoso cerebral. El diagnóstico es prenatal en alrededor del 25% de los casos. El tratamiento endovascular se lleva a cabo en torno a los 4-5 meses de edad o antes si existen factores de mal pronóstico. Las MAV parenquimatosas se diagnostican en menos del 20% de los casos en la infancia. Pueden revelarse por convulsiones o cefaleas, pero la hemorragia cerebral por ruptura es la primera manifestación. La ruptura de una MAV asociada a un coma es una urgencia medicoquirúrgica absoluta.
- Published
- 2023
- Full Text
- View/download PDF
6. Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity
- Author
-
Bakker, Mark K., Kanning, Jos P., Abraham, Gad, Martinsen, Amy E., Winsvold, Bendik S., Zwart, John-Anker, Bourcier, Romain, Sawada, Tomonobu, Koido, Masaru, Kamatani, Yoichiro, Morel, Sandrine, Amouyel, Philippe, Debette, Stéphanie, Bijlenga, Philippe, Berrandou, Takiy, Ganesh, Santhi K., Bouatia-Naji, Nabila, Jones, Gregory, Bown, Matthew, Rinkel, Gabriel J.E., Veldink, Jan H., Ruigrok, Ynte M., Hege Aamodt, Anne, Heidi Skogholt, Anne, Brumpton, Ben M, Willer, Cristen J, Sandset, Else C, Kristoffersen, Espen S, Ellekjær, Hanne, Heuch, Ingrid, Nielsen, Jonas B, Hagen, Knut, Hveem, Kristian, Fritsche, Lars G, Thomas, Laurent F, Pedersen, Linda M, Gabrielsen, Maiken E, Holmen, Oddgeir L, Børte, Sigrid, Zhou, Wei, Abboud, Shérine, Pandolfo, Massimo, Thijs, Vincent, Leys, Didier, Bodenant, Marie, Louillet, Fabien, Touzé, Emmanuel, Mas, Jean-Louis, Samson, Yves, Leder, Sara, Léger, Anne, Deltour, Sandrine, Crozier, Sophie, Méresse, Isabelle, Canaple, Sandrine, Godefroy, Olivier, Giroud, Maurice, Béjot, Yannick, Decavel, Pierre, Medeiros, Elizabeth, Montiel, Paola, Moulin, Thierry, Vuillier, Fabrice, Dallongeville, Jean, Metso, Antti J, Metso, Tiina, Tatlisumak, Turgut, Grond-Ginsbach, Caspar, Lichy, Christoph, Kloss, Manja, Werner, Inge, Arnold, Marie-Luise, Dos Santos, Michael, Grau, Armin, Dichgans, Martin, Thomas-Feles, Constanze, Weber, Ralf, Brandt, Tobias, Pezzini, Alessandro, De Giuli, Valeria, Caria, Filomena, Poli, Loris, Padovani, Alessandro, Bersano, Anna, Lanfranconi, Silvia, Beretta, Simone, Ferrarese, Carlo, Giacolone, Giacomo, Paolucci, Stefano, Lyrer, Philippe, Engelter, Stefan, Fluri, Felix, Hatz, Florian, Gisler, Dominique, Bonati, Leo, Gensicke, Henrik, Amort, Margareth, Markus, Hugh, Majersik, Jennifer, Worrall, Bradford, Southerland, Andrew, Cole, John, Kittner, Steven, Evangelou, Evangelos, Warren, Helen R, Gao, He, Ntritsos, Georgios, Dimou, Niki, Esko, Tonu, Mägi, Reedik, Milani, Lili, Almgren, Peter, Boutin, Thibaud, Ding, Jun, Giulianini, Franco, Holliday, Elizabeth G, Jackson, Anne U, Li-Gao, Ruifang, Lin, Wei-Yu, Luan, Jian’an, Mangino, Massimo, Oldmeadow, Christopher, Peter Prins, Bram, Qian, Yong, Sargurupremraj, Muralidharan, Shah, Nabi, Surendran, Praveen, Thériault, Sébastien, Verweij, Niek, Willems, Sara M, Zhao, Jing-Hua, Connell, John, de Mutsert, Renée, Doney, Alex SF, Farrall, Martin, Menni, Cristina, Morris, Andrew D, Noordam, Raymond, Paré, Guillaume, Poulter, Neil R, Shields, Denis C, Stanton, Alice, Thom, Simon, Abecasis, Gonçalo, Amin, Najaf, Arking, Dan E, Ayers, Kristin L, Barbieri, Caterina M, Batini, Chiara, Bis, Joshua C, Blake, Tineka, Bochud, Murielle, Boehnke, Michael, Boerwinkle, Eric, Boomsma, Dorret I, Bottinger, Erwin P, Braund, Peter S, Brumat, Marco, Campbell, Archie, Campbell, Harry, Chakravarti, Aravinda, Chambers, John C, Chauhan, Ganesh, Ciullo, Marina, Cocca, Massimiliano, Collins, Francis, Cordell, Heather J, Davies, Gail, de Borst, Martin H, de Geus, Eco J, Deary, Ian J, Deelen, Joris, Del Greco M, Fabiola, Yusuf Demirkale, Cumhur, Dörr, Marcus, Ehret, Georg B, Elosua, Roberto, Enroth, Stefan, Mesut Erzurumluoglu, A, Ferreira, Teresa, Frånberg, Mattias, Franco, Oscar H, Gandin, Ilaria, Gasparini, Paolo, Giedraitis, Vilmantas, Gieger, Christian, Girotto, Giorgia, Goel, Anuj, Gow, Alan J, Gudnason, Vilmundur, Guo, Xiuqing, Gyllensten, Ulf, Hamsten, Anders, Harris, Tamara B, Harris, Sarah E, Hartman, Catharina A, Havulinna, Aki S, Hicks, Andrew A, Hofer, Edith, Hofman, Albert, Hottenga, Jouke-Jan, Huffman, Jennifer E, Hwang, Shih-Jen, Ingelsson, Erik, James, Alan, Jansen, Rick, Jarvelin, Marjo-Riitta, Joehanes, Roby, Johansson, Åsa, Johnson, Andrew D, Joshi, Peter K, Jousilahti, Pekka, Wouter Jukema, J, Jula, Antti, Kähönen, Mika, Kathiresan, Sekar, Keavney, Bernard D, Khaw, Kay-Tee, Knekt, Paul, Knight, Joanne, Kolcic, Ivana, Kooner, Jaspal S, Koskinen, Seppo, Kristiansson, Kati, Kutalik, Zoltan, Laan, Maris, Larson, Marty, Launer, Lenore J, Lehne, Benjamin, Lehtimäki, Terho, Liewald, David CM, Lin, Li, Lind, Lars, Lindgren, Cecilia M, Liu, YongMei, Loos, Ruth JF, Lopez, Lorna M, Lu, Yingchang, Lyytikäinen, Leo-Pekka, Mahajan, Anubha, Mamasoula, Chrysovalanto, Marrugat, Jaume, Marten, Jonathan, Milaneschi, Yuri, Morgan, Anna, Morris, Andrew P, Morrison, Alanna C, Munson, Peter J, Nalls, Mike A, Nandakumar, Priyanka, Nelson, Christopher P, Niiranen, Teemu, Nolte, Ilja M, Nutile, Teresa, Oldehinkel, Albertine J, Oostra, Ben A, O’Reilly, Paul F, Org, Elin, Padmanabhan, Sandosh, Palmas, Walter, Palotie, Aarno, Pattie, Alison, WJH Penninx, Brenda, Perola, Markus, Peters, Annette, Polasek, Ozren, Pramstaller, Peter P, Tri Nguyen, Quang, Raitakari, Olli T, Rettig, Rainer, Rice, Kenneth, Ridker, Paul M, Ried, Janina S, Riese, Harriëtte, Ripatti, Samuli, Robino, Antonietta, Rose, Lynda M, Rotter, Jerome I, Rudan, Igor, Ruggiero, Daniela, Saba, Yasaman, Sala, Cinzia F, Salomaa, Veikko, Samani, Nilesh J, Sarin, Antti-Pekka, Schmidt, Reinhold, Schmidt, Helena, Shrine, Nick, Siscovick, David, Smith, Albert V, Snieder, Harold, Sõber, Siim, Sorice, Rossella, Starr, John M, Stott, David J, Strachan, David P, Strawbridge, Rona J, Sundström, Johan, Swertz, Morris A, Taylor, Kent D, Teumer, Alexander, Tobin, Martin D, Tomaszewski, Maciej, Toniolo, Daniela, Traglia, Michela, Trompet, Stella, Tuomilehto, Jaakko, Tzourio, Christophe, Uitterlinden, André G, Vaez, Ahmad, van der Most, Peter J, van Duijn, Cornelia M, Verwoert, Germaine C, Vitart, Veronique, Völker, Uwe, Vollenweider, Peter, Vuckovic, Dragana, Watkins, Hugh, Wild, Sarah H, Willemsen, Gonneke, Wilson, James F, Wright, Alan F, Yao, Jie, Zemunik, Tatijana, Zhang, Weihua, Attia, John R, Butterworth, Adam S, Chasman, Daniel I, Conen, David, Cucca, Francesco, Danesh, John, Hayward, Caroline, Howson, Joanna MM, Laakso, Markku, Lakatta, Edward G, Langenberg, Claudia, Melander, Olle, Mook-Kanamori, Dennis O, Palmer, Colin NA, Risch, Lorenz, Scott, Robert A, Scott, Rodney J, Sever, Peter, Spector, Tim D, van der Harst, Pim, Wareham, Nicholas J, Zeggini, Eleftheria, Levy, Daniel, Munroe, Patricia B, Newton-Cheh, Christopher, Brown, Morris J, Metspalu, Andres, Psaty, Bruce M., Wain, Louise V, Elliott, Paul, Caulfield, Mark J, Gormley, Padhraig, Anttila, Verneri, Palta, Priit, Esko, Tonu, Pers, Tune H, Farh, Kai-How, Cuenca-Leon, Ester, Muona, Mikko, Furlotte, Nicholas A, Kurth, Tobias, Ingason, Andres, McMahon, George, Ligthart, Lannie, Terwindt, Gisela M, Kallela, Mikko, Freilinger, Tobias M, Ran, Caroline, Gordon, Scott G, Stam, Anine H, Steinberg, Stacy, Borck, Guntram, Koiranen, Markku, Quaye, Lydia, Adams, Hieab H H, Lehtimäki, Terho, Sarin, Antti-Pekka, Wedenoja, Juho, Hinds, David A, Buring, Julie E, Schürks, Markus, Ridker, Paul M, Gudlaug Hrafnsdottir, Maria, Stefansson, Hreinn, Ring, Susan M, Hottenga, Jouke-Jan, Penninx, Brenda W J H, Färkkilä, Markus, Artto, Ville, Kaunisto, Mari, Vepsäläinen, Salli, Malik, Rainer, Heath, Andrew C, Madden, Pamela A F, Martin, Nicholas G, Montgomery, Grant W, Kurki, Mitja I, Kals, Mart, Mägi, Reedik, Pärn, Kalle, Hämäläinen, Eija, Huang, Hailiang, Byrnes, Andrea E, Franke, Lude, Huang, Jie, Stergiakouli, Evie, Lee, Phil H, Sandor, Cynthia, Webber, Caleb, Cader, Zameel, Muller-Myhsok, Bertram, Schreiber, Stefan, Meitinger, Thomas, Eriksson, Johan G, Salomaa, Veikko, Heikkilä, Kauko, Loehrer, Elizabeth, Uitterlinden, Andre G, Hofman, Albert, van Duijn, Cornelia M, Cherkas, Lynn, Pedersen, Linda M, Stubhaug, Audun, Nielsen, Christopher S, Männikkö, Minna, Mihailov, Evelin, Milani, Lili, Göbel, Hartmut, Esserlind, Ann-Louise, Francke Christensen, Anne, Folkmann Hansen, Thomas, Werge, Thomas, Kaprio, Jaakko, Aromaa, Arpo J, Raitakari, Olli, Arfan Ikram, M, Spector, Tim, Järvelin, Marjo-Riitta, Metspalu, Andres, Kubisch, Christian, Strachan, David P, Ferrari, Michel D, Belin, Andrea C, Dichgans, Martin, Wessman, Maija, van den Maagdenberg, Arn M J M, Boomsma, Dorret I, Davey Smith, George, Stefansson, Kari, Eriksson, Nicholas, Daly, Mark J, Neale, Benjamin M, Olesen, Jes, Chasman, Daniel I, Nyholt, Dale R, Palotie, Aarno, Akiyama, Masato, Alg, Varinder S., Børte, Sigrid, Broderick, Joseph P., Brumpton, Ben M., Dauvillier, Jérôme, Desal, Hubert, Dina, Christian, Friedrich, Christoph M., Gaál-Paavola, Emília I., Gentric, Jean-Christophe, Hirsch, Sven, Hostettler, Isabel C., Houlden, Henry, Hveem, Kristian, Jääskeläinen, Juha E., Johnsen, Marianne Bakke, Li, Liming, Lin, Kuang, Lindgren, Antti, Martin, Olivier, Matsuda, Koichi, Millwood, Iona Y., Naggara, Olivier, Niemelä, Mika, Pera, Joanna, Redon, Richard, Rouleau, Guy A., Sandvei, Marie Søfteland, Schilling, Sabine, Shotar, Eimad, Slowik, Agnieszka, Terao, Chikashi, Verschuren, W. M. Monique, Walters, Robin G., Werring, David J., Willer, Cristen J., Woo, Daniel, Worrall, Bradford B., and Zhou, Sirui
- Published
- 2023
- Full Text
- View/download PDF
7. Successful thrombectomy is beneficial in patients with pre-stroke disability: Results from an international multicenter cohort study
- Author
-
Ducroux, Célina, Derex, Laurent, Nourredine, Mikaïl, Haesebaert, Julie, Buisson, Marielle, Alesefir, Walid, Boisseau, William, Daneault, Nicole, Deschaintre, Yan, Diestro, Jose Danilo B., Eker, Omer, Eneling, Johanna, Gioia, Laura C., Iancu, Daniella, Jacquin, Grégory, Odier, Céline, Stapf, Christian, Raymond, Jean, Roy, Daniel, Weill, Alain, Lapergue, Bertrand, Poppe, Alexandre Y., Piotin, Michel, Blanc, Raphael, Escalard, Hocine Redjem Simon, Desilles, Jean-Philippe, Delvoye, François, Smajda, Stanislas, Maier, Benjamin, Hebert, Solène, Mazighi, Mikael, Obadia, Mikael, Sabben, Candice, Seners, Pierre, Raynouard, Igor, Corabianu, Ovide, de Broucker, Thomas, Manchon, Eric, Taylor, Guillaume, Ben Maacha, Malek, Thion, Laurie-Anne, Lecler, Augustin, Savatovsky, Julien, Wang, Adrien, Evrard, Serge, Tchikviladze, Maya, Ajili, Nadia, Lapergue, Bertrand, Weisenburger-Lile, David, Gorza, Lucas, Buard, Géraldine, Coskun, Oguzhan, Consoli, Arturo, Di Maria, Federico, Rodesh, Georges, Zimatore, Sergio, Leguen, Morgan, Gratieux, Julie, Pico, Fernando, Rakotoharinandrasana, Haja, Tassan, Philippe, Poll, Roxanna, Marinier, Sylvie, Nighoghossian, Norbert, Riva, Roberto, Eker, Omer, Turjman, Francis, Derex, Laurent, Cho, Tae-Hee, Mechtouff, Laura, Lukaszewicz, Anne Claire, Philippeau, Frédéric, Cakmak, Serkan, Blanc-Lasserre, Karine, Vallet, Anne-Evelyne, Marnat, Gaultier, Gariel, Florent, Barreau, Xavier, Berge, Jérôme, Menegon, Patrice, Sibon, Igor, Lucas, Ludovic, Olindo, Stéphane, Renou, Pauline, Sagnier, Sharmila, Poli, Mathilde, Debruxelles, Sabrina, Rouanet, François, Tourdias, Thomas, Liegey, Jean-Sebastien, Briau, Pierre, Pangon, Nicolas, Bourcier, Romain, Detraz, Lili, Daumas-Duport, Benjamin, Alexandre, Pierre-Louis, Roy, Monica, Lenoble, Cédric, Desal, Hubert, Guillon, Benoît, de Gaalon, Solène, Preterre, Cécile, Gory, Benjamin, Bracard, Serge, Anxionnat, René, Braun, Marc, Derelle, Anne-Laure, Tonnelet, Romain, Liao, Liang, Zhu, François, Schmitt, Emmanuelle, Planel, Sophie, Richard, Sébastien, Humbertjean, Lisa, Mione, Gioia, Lacour, Jean-Christophe, Riou-Comte, Nolwenn, Audibert, Gérard, Voicu, Marcela, Alb, Ionel, Reitter, Marie, Brezeanu, Madalina, Masson, Agnès, Tabarna, Adriana, Podar, Iona, Macian-montoro, Francisco, Saleme, Suzanna, Mounayer, Charbel, Rouchaud, Aymeric, Costalat, Vincent, Arquizan, Caroline, Dargazanli, Cyril, Gascou, Grégory, Lefèvre, Pierre-Henri, Derraz, Imad, Riquelme, Carlos, Gaillard, Nicolas, Mourand, Isabelle, Corti, Lucas, Cagnazzo, Federico, ter Schiphorst, Adrien, Francois, Eugene, Vannier, Stéphane, Ferre, Jean-christophe, Raoult, Helene, Ronziere, Thomas, Lassale, Maria, Paya, Christophe, Gauvrit, Jean-Yves, Tracol, Clément, Langnier-Lemercier, Sophie, Samson, Yves, Rosso, Charlotte, Leger, Anne, Deltour, Sandrine, Clarencon, Frederic, Shotar, Eimad, Spelle, Laurent, Denier, Christian, Chassin, Olivier, Chalumeau, Vanessa, Caroff, Jildaz, Chassin, Olivier, Venditti, Laura, Naggara, Olivier, Hassen, Wagih Ben, Boulouis, Grégoire, Rodriguez-Régent, Christine, Trystram, Denis, Kerleroux, Basile, Turc, Guillaume, Domigo, Valérie, Lamy, Catherine, Birchenall, Julia, Isabel, Clothilde, Lun, François, Viguier, Alain, Cognard, Christophe, Januel, Anne Christine, Olivot, Jean-Marc, Raposo, Nicolas, Bonneville, Fabrice, Albucher, Jean François, Calviere, Lionel, Darcourt, Jean, Tall, Philippe, Bellanger, Guillaume, Fontaine, Louis, Touze, Emmanuel, Barbier, Charlotte, Schneckenburger, Romain, Boulanger, Marion, Cogez, Julien, Guettier, Sophie, Timsit, Serge, Gentric, Jean-christophe, Ognard, Julien, Merrien, Francois Mathias, Wermester, Ozlem Ozkul, Massardier, Evelyne, Papagiannaki, Chrysanthi, Bourdain, Frédéric, Bernady, Patricia, Lagoarde-Segot, Laurent, Cailliez, Hélène, Veunac, Louis, Higue, David, Wolff, Valérie, Pop, Raoul, Beaujeux, Rémi, Dan-Sorin, Mihoc, Manisor, Monica, Le Bras, Anthony, Evain, Sarah, Le Guen, Arnaud, Richter, Sebastian, Hubrecht, Regis, Demasles, Stéphanie, Barroso, Bruno, Sablot, Denis, Farouil, Geoffroy, Tardieu, Maxime, Smadja, Philippe, Aptel, Sabine, and Seiler, Ian
- Abstract
Patients with pre-stroke disability, defined as a modified Rankin Scale (mRS) ≥3, were excluded from most trials of endovascular thrombectomy (EVT) for acute stroke. We sought to evaluate the prognostic factors associated with favorable outcome in stroke patients with known disability undergoing EVT, and the impact of successful reperfusion.
- Published
- 2023
- Full Text
- View/download PDF
8. MR imaging of the Adnexa
- Author
-
Rockall, Andrea G., Jalaguier-Coudray, Aurélie, and Thomassin-Naggara, Isabelle
- Abstract
MR imaging has a high diagnostic accuracy and reproducibility to classify adnexal masses as benign or malignant, using a risk stratification scoring system, the Ovarian-Adnexal Reporting and Data System (O-RADS) MR imaging score. The first step in achieving high accuracy is to ensure high technical quality of the MR scan. The sequences needed are clearly described in this article, with tips for handling difficult cases. This information will assist in obtaining the best possible images, to allow for accurate use of the O-RADS MR imaging risk score.
- Published
- 2023
- Full Text
- View/download PDF
9. Risk factors of unexplained early neurological deterioration after treatment for ischemic stroke due to large vessel occlusion: a post hoc analysis of the HERMES study
- Author
-
Bourcier, Romain, Goyal, Mayank, Muir, Keith W, Desal, Hubert, Dippel, Diederik W J, Majoie, Charles B L M, van Zwam, Wim H, Jovin, Tudor G, Mitchell, Peter J, Demchuk, Andrew M, van Oostenbrugge, Robert J, Brown, Scott B, Campbell, Bruce, White, Philip, Hill, Michael D, Saver, Jeffrey L, Weimar, Christian, Jahan, Reza, Guillemin, Francis, Bracard, Serge, and Naggara, Olivier
- Abstract
BackgroundEarly neurological deterioration (END) after endovascular treatment (EVT) in patients with anterior circulation acute ischemic stroke (AIS) is associated with poor outcome. END may remain unexplained by parenchymal hemorrhage (UnEND). We aim to analyze the risk factors of UnEND in the medical management (MM) and EVT arms of the HERMES study.MethodsWe conducted a post-hoc analysis of anterior AIS patients who underwent EVT for proximal anterior occlusions. Risk factors of UnEND, defined as a worsening of ≥4 points between baseline National Institutes of Health Stroke Scale (NIHSS) and NIHSS at 24 hours without hemorrhage, were compared between both arms using mixed logistic regression models adjusted for baseline characteristics. An interaction analysis between the EVT and MM arms for risk factors of UnEND was conducted.ResultsAmong 1723 patients assessable for UnEND, 160 patients experienced an UnEND (9.3%), including 9.1% (78/854) in the EVT arm and 9.4% (82/869) in the MM arm. There was no significant difference in the incidence of UnEND between the two study arms. In the EVT population, independent risk factors of UnEND were lower baseline NIHSS, higher baseline glucose, and lower collateral grade. In the MM population, the only independent predictor of UnEND was higher baseline glucose. However, we did not demonstrate an interaction between EVT and MM for baseline factors as risk factors of UnEND. UnEND was, similarly in both treatment groups, a significant predictor of unfavorable outcome in both the EVT (p<0.001) and MM (p<0.001) arms.ConclusionsUnEND is not an uncommon event, with a similar rate which ever treatment arm is considered. In the clinical scenario of AIS due to large vessel occlusion, no patient-related factor seems to increase the risk for UnEND when treated by EVT compared with MM.
- Published
- 2023
- Full Text
- View/download PDF
10. Influence of prior intravenous thrombolysis in patients treated with mechanical thrombectomy for M2 occlusions: insight from the Endovascular Treatment in Ischemic Stroke (ETIS) registry
- Author
-
Le Floch, Agathe, Clarencon, Frédéric, Rouchaud, Aymeric, Kyheng, Maeva, Labreuche, Julien, Sibon, Igor, Boulouis, Gregoire, Gory, Benjamin, Richard, Sébastien, Caroff, Jildaz, Blanc, Raphae¨l, Seners, Pierre, Eker, Omer F, Cho, Tae-Hee, Consoli, Arturo, Bourcier, Romain, guillon, benoit, Dargazanli, Cyril, Arquizan, Caroline, Denier, Christian, Eugene, Francois, Vannier, Stephane, Gentric, Jean-Christophe, Gauberti, Maxime, Naggara, Olivier, Rosso, Charlotte, Turc, Guillaume, Ozkul-Wermester, Ozlem, Cognard, Christophe, Albucher, Jean Francois, Timsit, Serge, Bourdain, Frederic, Le Bras, Anthony, Richter, Sebastian, Moulin, Solène, Pop, Raoul, Heck, Olivier, Moreno, Ricardo, L'Allinec, Vincent, Lapergue, Bertrand, and Marnat, Gaultier
- Abstract
BackgroundIntravenous thrombolysis (IVT) for patients treated with mechanical thrombectomy (MT) for proximal occlusions has recently been questioned through randomized trials. However, few patients with M2 occlusions were included. We investigated the influence of prior IVT for patients presenting M2 occlusions treated with MT in comparison with MT alone.MethodsWe conducted a retrospective analysis of the Endovascular Treatment in Ischemic Stroke (ETIS) registry, a multicenter observational study. Data from consecutive patients treated with MT for M2 occlusions between January 2015 and January 2022 at 26 comprehensive stroke centers were analyzed. The primary endpoint was 90-day modified Rankin Scale score of 0–2. Outcomes were compared using propensity score approaches. We also performed sensitivity analysis in relevant subgroups of patients.ResultsAmong 1132 patients with M2 occlusions treated with MT, 570 received prior IVT. The two groups were comparable after propensity analysis. The rate of favorable functional outcome was significantly higher in the IVT+MT group compared with the MT alone group (59.8% vs 44.7%; adjusted OR 1.38, 95% CI 1.10 to 1.75, P=0.008). Hemorrhagic and procedural complications were similar in both groups. In sensitivity analysis excluding patients with anticoagulation treatment, favorable recanalization was more frequent in the IVT+MT group (OR 1.37, 95% CI 1.11 to 1.70, P=0.004).ConclusionsIn cases of M2 occlusions, prior IVT combined with MT resulted in better functional outcome than MT alone, without increasing the rate of hemorrhagic or procedural complications. These results suggest the benefit of IVT in patients undergoing MT for M2 occlusions.
- Published
- 2023
- Full Text
- View/download PDF
11. Aspirin versus aggressive antiplatelet therapy for acute carotid stenting plus thrombectomy in tandem occlusions: ETIS Registry results
- Author
-
Marnat, Gaultier, Finistis, Stefanos, Moreno, Ricardo, Sibon, Igor, Pop, Raoul, Mazighi, Mikae¨l, Clarencon, Frédéric, Rosso, Charlotte, Dargazanli, Cyril, Darcourt, Jean, Olivot, Jean-Marc, Boulouis, Gregoire, Janot, Kevin, Moulin, Solène, Bourcier, Romain, Consoli, Arturo, Richard, Sébastien, Arquizan, Caroline, Vannier, Stephane, Richter, Sebastian, Gentric, Jean-Christophe, Papagiannaki, Chrisanthi, Naggara, Olivier, Eker, Omer F, Lapergue, Bertrand, Caroff, Jildaz, and Gory, Benjamin
- Abstract
BackgroundPatients treated with acute carotid stenting (CAS) may have higher odds of a favorable outcome than those treated without CAS during thrombectomy in tandem occlusions. Antiplatelet therapy is associated with CAS to avoid stent thrombosis, which occurs in around 20% of patients and negatively impacts outcomes. In this study we compared two antiplatelet strategies in tandem occlusion strokes treated with CAS and intracranial thrombectomy in clinical practice.MethodsThe Endovascular Treatment in Ischemic Stroke Registry is an ongoing prospective observational study involving 21 comprehensive stroke centers performing thrombectomy in France. We analyzed patients with atherosclerotic tandem occlusions treated with acute CAS and intracranial thrombectomy who received at least one antiplatelet agent. Aggressive antiplatelet therapy included oral or intravenous glycoprotein (GP) IIb/IIIa or P2Y12 inhibitors. The primary outcome was cervical carotid artery patency at day 1 imaging follow-up.ResultsAmong the 187 included patients, 124 (66.3%) received aspirin alone and 63 (33.7%) received aggressive antiplatelet therapy. There was no significant difference regarding safety outcomes, especially in symptomatic intracerebral hemorrhage, parenchymal hematoma, and procedural complications. There was a significantly higher rate of carotid stent patency at day 1 in the aggressive antiplatelet therapy group (81.7% vs 97.1%, aOR 17.49, 95% CI 1.10 to 277.2, p=0.042). Odds of favorable functional outcome (90-day modified Rankin Scale score 0–2) were similar between the groups (OR 3.04, 95% CI 0.64 to 14.25, p=0.158).ConclusionsIn tandem occlusions treated with CAS plus thrombectomy, an aggressive antiplatelet regimen was associated with an increased rate of carotid stent patency at day 1 without safety concerns. Randomized trials are warranted to confirm these findings.
- Published
- 2023
- Full Text
- View/download PDF
12. Poor clinical outcome despite successful basilar occlusion recanalization in the early time window: incidence and predictors
- Author
-
Pop, Raoul, Finitsis, Stephanos Nikolaos, Arquizan, Caroline, Elhorany, Mahmoud, Naggara, Olivier, Darcourt, Jean, Clarencon, Frédéric, Richard, Sébastien, Marnat, Gaultier, Bourcier, Romain, Sibon, Igor, Dargazanli, Cyril, Blanc, Raphae¨l, Lapergue, Bertrand, Consoli, Arturo, Eugene, Francois, Vannier, Stephane, Caroff, Jildaz, Denier, Christian, Boulanger, Marion, Gauberti, Maxime, Rouchaud, Aymeric, Macian, Francisco, Rosso, Charlotte, Turc, Guillaume, Ozkul-Wermester, Ozlem, Albucher, Jean Francois, Le Bras, Anthony, Evain, Sarah, Wolff, Valerie, Timsit, Serge, Gentric, Jean-Christophe, Bourdain, Frédéric, Veunac, Louis, Papagiannaki, Chrysanthi, and Gory, Benjamin
- Abstract
BackgroundEndovascular treatment (EVT) for basilar artery occlusions (BAO) is associated with a higher rate of futile recanalization compared with anterior circulation procedures. We aimed to identify the incidence and predictors of poor clinical outcome despite successful reperfusion in current clinical practice.MethodsWe used data from the ETIS (Endovascular Treatment in Ischemic Stroke) registry, a prospective multicenter observational registry of stroke treated with EVT in France. Patients undergoing EVT for acute BAO from January 2014 to May 2019 successfully treated within 8 hours from onset were included. Predictors of 90-day poor outcome (modified Rankin Scale (mRS) 4–6) were researched within patients with successful (modified Thrombolysis In Cerebral Infarction (mTICI 2b-3)) and excellent (mTICI 2c-3) reperfusion.ResultsAmong 242 patients treated within 8 hours, successful reperfusion was achieved in 195 (80.5%) and excellent reperfusion in 120 (49.5%). Poor outcome was observed in 107 (54.8%) and 60 (50%) patients, respectively. In patients with successful early reperfusion, age, higher initial National Institutes of Health Stroke Scale (NIHSS) score, lower posterior circulation Alberta Stroke Programme Early CT Score (pc-ASPECTS), and absence of prior intravenous thrombolysis were independent predictors of poor outcome. The only treatment factor with an independent predictive value was first-pass mTICI 2b-3 reperfusion (adjusted OR 0.13, 95% CI 0.05 to 0.37, p<0.001). In patients with excellent early reperfusion, independent predictors were age, initial NIHSS score, first-pass mTICI 2c-3 reperfusion, and hemorrhagic transformation on post-interventional imaging.ConclusionsEarly successful reperfusion with EVT occurred in 80.5% of patients, and the only treatment-related factor predictive of clinical outcome was first pass mTICI 2b-3 reperfusion. Further research is warranted to identify the optimal techniques and devices associated with first pass reperfusion in the posterior circulation.
- Published
- 2023
- Full Text
- View/download PDF
13. Thrombectomy in basilar artery occlusions: impact of number of passes and futile reperfusion
- Author
-
de Havenon, Adam, Elhorany, Mahmoud, Boulouis, Gregoire, Naggara, Olivier, Darcourt, Jean, Clarencon, Frédéric, Richard, Sébastien, Marnat, Gaultier, Bourcier, Romain, Sibon, Igor, Arquizan, Caroline, Dargazanli, Cyril, Mai¨er, Benjamin, Seners, Pierre, Lapergue, Bertrand, Consoli, Arturo, Eugene, Francois, Vannier, Stephane, Caroff, Jildaz, Denier, Christian, Boulanger, Marion, Gauberti, Maxime, Rouchaud, Aymeric, Macian, Francisco, Rosso, Charlotte, Turc, Guillaume, Ozkul-Wermester, Ozlem, Papagiannaki, Chrisanthi, Albucher, Jean Francois, Le Bras, Anthony, Evain, Sarah, Wolff, Valerie, Pop, Raoul, Timsit, Serge, Gentric, Jean-Christophe, Bourdain, Frédéric, Veunac, Louis, Fahed, Robert, Finitsis, Stephanos Nikolaos, and Gory, Benjamin
- Abstract
BackgroundThe number of mechanical thrombectomy (MT) passes is strongly associated with angiographic reperfusion as well as clinical outcomes in patients with anterior circulation ischemic stroke. However, these associations have not been analyzed in patients with basilar artery occlusion (BAO). We investigated the influence of the number of MT passes on the degree of reperfusion and clinical outcomes, and compared outcome after ≤3 passes versus >3 passes.MethodsWe used data from the prospective multicentric Endovascular Treatment in Ischemic Stroke (ETIS) Registry at 18 sites in France. Patients with BAO treated with MT were included. The primary outcome was a favorable outcome, defined as a modified Rankin Scale score of 0–3 at 90 days. We fit mixed multiple regression models, with center as a random effect.ResultsWe included 275 patients. Successful recanalization (modified Thrombolysis In Cerebral Infarction (mTICI) 2b-3) was achieved in 88.4%, and 41.8% had a favorable outcome. The odds ratio for favorable outcome with each pass above 1 was 0.41 (95% CI 0.23 to 0.73) and for recanalization (mTICI 2b-3) it was 0.70 (95% CI 0.57 to 0.87). In patients with ≤3 passes, the rate of favorable outcome in recanalized versus non-recanalized patients was 50.5% versus 10.0% (p=0.001), while in those with >3 passes it was 16.7% versus 15.2% (p=0.901).ConclusionsWe found that BAO patients had a significant relationship between the number of MT passes and both recanalization and favorable functional outcome. We further found that the benefit of recanalization in BAO patients was significant only when recanalization was achieved within three passes, encouraging at least three passes before stopping the procedure.
- Published
- 2023
- Full Text
- View/download PDF
14. TAGE Score for Symptomatic Intracranial Hemorrhage Prediction After Successful Endovascular Treatment in Acute Ischemic Stroke
- Author
-
Janvier, Paul, Kerleroux, Basile, Turc, Guillaume, Pasi, Marco, Farhat, Wassim, Bricout, Nicolas, Benzakoun, Joseph, Legrand, Laurence, Clarençon, Frédéric, Bracard, Serge, Oppenheim, Catherine, Boulouis, Grégoire, Henon, Hilde, Naggara, Olivier, and Ben Hassen, Wagih
- Published
- 2022
- Full Text
- View/download PDF
15. O-RADS MRI Classification of Indeterminate Adnexal Lesions: Time-Intensity Curve Analysis Is Better Than Visual Assessment
- Author
-
Wengert, Georg J., Dabi, Yohann, Kermarrec, Edith, Jalaguier-Coudray, Aurélie, Poncelet, Edouard, Porcher, Raphaël, Thomassin-Naggara, Isabelle, and Rockall, Andrea G.
- Abstract
Time-intensity curve analysis is more accurate than visual assessment to achieve optimal diagnostic accuracy with the Ovarian-Adnexal Reporting and Data System MRI score.
- Published
- 2022
- Full Text
- View/download PDF
16. O-RADS MRI Risk Stratification System: Guide for Assessing Adnexal Lesions from the ACR O-RADS Committee
- Author
-
Sadowski, Elizabeth A., Thomassin-Naggara, Isabelle, Rockall, Andrea, Maturen, Katherine E., Forstner, Rosemarie, Jha, Priyanka, Nougaret, Stephanie, Siegelman, Evan S., and Reinhold, Caroline
- Abstract
The Ovarian-Adnexal Reporting and Data System MRI risk score is a stratification system for assigning malignancy probability to adnexal lesions and can improve communication between radiologists and referring physicians to optimize treatment of women with adnexal lesions.
- Published
- 2022
- Full Text
- View/download PDF
17. Synthetic FLAIR as a Substitute for FLAIR Sequence in Acute Ischemic Stroke
- Author
-
Benzakoun, Joseph, Deslys, Marc-Antoine, Legrand, Laurence, Hmeydia, Ghazi, Turc, Guillaume, Hassen, Wagih Ben, Charron, Sylvain, Debacker, Clément, Naggara, Olivier, Baron, Jean-Claude, Thirion, Bertrand, and Oppenheim, Catherine
- Abstract
Synthetic fluid-attenuated inversion recovery (FLAIR) generated with deep learning is as accurate as a real FLAIR sequence for the identification of early stroke.
- Published
- 2022
- Full Text
- View/download PDF
18. Influence of prior intravenous thrombolysis on outcome after failed mechanical thrombectomy: ETIS registry analysis
- Author
-
Rozes, Claire, Maier, Benjamin, Gory, Benjamin, Bourcier, Romain, Kyheng, Maeva, Labreuche, Julien, Consoli, Arturo, Mazighi, Mikael, Blanc, Raphae¨l, Caroff, Jildaz, Eugene, Francois, Naggara, Olivier, Gariel, Florent, Sibon, Igor, Lapergue, Bertrand, and Marnat, Gaultier
- Abstract
BackgroundDespite constant improvements in recent years, sufficient reperfusion after mechanical thrombectomy (MT) is not reached in up to 15% of patients with large vessel occlusion stroke (LVOS). The outcome of patients with unsuccessful reperfusion after MT especially after intravenous thrombolysis (IVT) use is not known. We investigated the influence of initial IVT in this particular group of patients with failed intracranial recanalization.MethodsWe conducted a retrospective analysis of the Endovascular Treatment in Ischemic Stroke (ETIS) registry from January 2015 to December 2019. Patients presenting with LVOS of the anterior circulation and final modified Thrombolysis in Cerebral Infarction score (mTICI) of 0, 1 or 2a were included. Posterior circulation, isolated cervical carotid occlusions and successful reperfusions (mTICI 2b, 2c or 3) were excluded. The primary endpoint was favorable outcome (modified Rankin Scale score of 0–2) after 3 months. Secondary endpoints were safety outcomes including mortality, any intracranial hemorrhage (ICH), parenchymal hematoma (PH) and symptomatic intracranial hemorrhage (sICH) rates.ResultsAmong 5076 patients with LVOS treated with MT, 524 patients with insufficient recanalization met inclusion criteria, of which 242 received IVT and 282 did not. Functional outcome was improved in the MT+IVT group compared with the MT alone group, although the difference did not reach statistical significance (23.0% vs 12.9%; adjusted OR=1.82; 95% CI 0.98 to 3.38; p=0.058). However, 3 month mRS shift analysis showed a significant benefit of IVT (adjusted OR=1.68; 95% CI 1.56 to 6.54). ICH and sICH rates were similar in both groups, although PH rate was higher in the MT+IVT group (adjusted OR=3.20; 95% CI 1.56 to 6.54).ConclusionsAmong patients with LVOS in the anterior circulation and unsuccessful MT, IVT was associated with improved functional outcome even after unsuccessful MT. Despite recent trials questioning the place of IVT in the LVOS reperfusion strategy, these findings emphasize a subgroup of patients still benefiting from IVT.
- Published
- 2022
- Full Text
- View/download PDF
19. Pediatric brain arteriovenous malformation recurrence: a cohort study, systematic review and meta-analysis
- Author
-
Hak, Jean-Francois, Boulouis, Gregoire, Kerleroux, Basile, Benichi, Sandro, Stricker, Sarah, Gariel, Florent, Garzelli, Lorenzo, Meyer, Philippe, Kossorotoff, Manoelle, Boddaert, Nathalie, Vidal, Vincent, Girard, Nadine, Dangouloff-Ros, Volodia, Brunelle, Francis, Fullerton, Heather, Hetts, Steven W, Blauwblomme, Thomas, and Naggara, Olivier
- Abstract
BackgroundRecurrence following obliteration of brain arteriovenous malformations (AVMs) is common in children surgically treated, but recurrences following endovascular (EVT) and radiosurgical approaches are scantily reported.ObjectiveTo analyze the rates and risk factors for AVM recurrence after obliteration in a single-center cohort of children with ruptured AVMs treated with multimodal approaches, and to carry out a comprehensive review and meta-analysis of current data.MethodsChildren with ruptured AVMs between 2000 and 2019 enrolled in a prospective registry were retrospectively screened and included after angiographically determined obliteration to differentiate children with/without recurrence. A complementary systematic review and meta-analysis of studies investigating AVM recurrence in children between 2000 and 2020 was aggregated to explore the overall recurrence rates across treatment modalities by analyzing surgery versus other treatments.ResultsSeventy children with obliterated AVMs were included. AVM recurrences (n=10) were more commonly treated with EVT as final treatment (60% in the recurrence vs 13.3% in the no-recurrence group, p=0.018). Infratentorial locations were associated with earlier and more frequent recurrences (adjusted relative risk=4.62, 95% CI 1.08 to 19.04; p=0.04).In the aggregate analysis, the pooled rate of AVM recurrence was 10.9% (95% CI 8.7% to 13.5%). Younger age at presentation was associated with more frequent recurrences (RR per year increase, 0.97, 95% CI 0.93 to 0.99; p=0.046).ConclusionLocation of infratentorial AVMs and younger age at presentation may be associated with earlier and more frequent recurrences. The higher rates of recurrence in patients with AVMs obliterated with EVT questions its role in an intent-to-cure approach and reinforces its position as an adjunct to surgery and/or radiosurgery.
- Published
- 2022
- Full Text
- View/download PDF
20. Collateral status reperfusion and outcomes after endovascular therapy: insight from the Endovascular Treatment in Ischemic Stroke (ETIS) Registry
- Author
-
Anadani, Mohammad, Finitsis, Stephanos, Clarencon, Frédéric, Richard, Sébastien, Marnat, Gaultier, Bourcier, Romain, Sibon, Igor, Dargazanli, Cyril, Arquizan, Caroline, Blanc, Raphael, Lapergue, Bertrand, Consoli, Arturo, Eugene, Francois, Vannier, Stephane, Spelle, Laurent, Denier, Christian, Boulanger, Marion, Gauberti, Maxime, Liebeskind, David S, de Havenon, Adam, Saleme, Suzana, Macian, Francisco, Rosso, Charlotte, Naggara, Olivier, Turc, Guillaume, Ozkul-Wermester, Ozlem, Papagiannaki, Chrisanthi, Viguier, Alain, Cognard, Christophe, Le Bras, Anthony, Evain, Sarah, Wolff, Valerie, Pop, Raoul, Timsit, Serge, Gentric, Jean-Christophe, Bourdain, Frédéric, Veunac, Louis, Maier, Benjamin, and Gory, Benjamin
- Abstract
BackgroundStudies have suggested that collateral status modifies the effect of successful reperfusion on functional outcome after endovascular therapy (EVT). We aimed to assess the association between collateral status and EVT outcomes and to investigate whether collateral status modified the effect of successful reperfusion on EVT outcomes.MethodsWe used data from the ongoing, prospective, multicenter Endovascular Treatment in Ischemic Stroke (ETIS) Registry. Collaterals were graded according to the American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology (ASITN/SIR) guidelines. Patients were divided into two groups based on angiographic collateral status: poor (grade 0–2) versus good (grade 3–4) collaterals.ResultsAmong 2020 patients included in the study, 959 (47%) had good collaterals. Good collaterals were associated with favorable outcome (90-day modified Rankin Scale (mRS) 0–2) (OR 1.5, 95% CI 1.19 to 1.88). Probability of good outcome decreased with increased time from onset to reperfusion in both good and poor collateral groups. Successful reperfusion was associated with higher odds of favorable outcome in good collaterals (OR 6.01, 95% CI 3.27 to 11.04) and poor collaterals (OR 5.65, 95% CI 3.32 to 9.63) with no significant interaction. Similarly, successful reperfusion was associated with higher odds of excellent outcome (90-day mRS 0–1) and lower odds of mortality in both groups with no significant interaction. The benefit of successful reperfusion decreased with time from onset in both groups, but the curve was steeper in the poor collateral group.ConclusionsCollateral status predicted functional outcome after EVT. However, collateral status on the pretreatment angiogram did not decrease the clinical benefit of successful reperfusion.
- Published
- 2022
- Full Text
- View/download PDF
21. Arterial Spin Labeling for the Etiological Workup of Intracerebral Hemorrhage in Children
- Author
-
Hak, Jean François, Boulouis, Grégoire, Kerleroux, Basile, Benichi, Sandro, Stricker, Sarah, Gariel, Florent, Garzelli, Lorenzo, Meyer, Philippe, Kossorotoff, Manoelle, Boddaert, Nathalie, Vidal, Vincent, Girard, Nadine, Dangouloff Ros, Volodia, Brunelle, Francis, Blauwblomme, Thomas, and Naggara, Olivier
- Abstract
Supplemental Digital Content is available in the text.
- Published
- 2022
- Full Text
- View/download PDF
22. Thrombectomy Complications in Large Vessel Occlusions: Incidence, Predictors, and Clinical Impact in the ETIS Registry
- Author
-
Happi Ngankou, Emmanuel, Gory, Benjamin, Marnat, Gaultier, Richard, Sébastien, Bourcier, Romain, Sibon, Igor, Dargazanli, Cyril, Arquizan, Caroline, Maïer, Benjamin, Blanc, Raphaël, Lapergue, Bertrand, Consoli, Arturo, Vannier, Stéphane, Spelle, Laurent, Denier, Christian, Boulanger, Marion, Gauberti, Maxime, Saleme, Suzana, Macian, Francisco, Clarençon, Frédéric, Rosso, Charlotte, Naggara, Olivier, Turc, Guillaume, Ozkul-Wermester, Ozlem, Papagiannaki, Chrysanthi, Viguier, Alain, Cognard, Christophe, Lebras, Anthony, Evain, Sarah, Wolff, Valérie, Pop, Raoul, Timsit, Serge, Gentric, Jean-Christophe, Bourdain, Frédéric, Veunac, Louis, Eugène, François, and Finitsis, Stephanos
- Abstract
Supplemental Digital Content is available in the text.
- Published
- 2021
- Full Text
- View/download PDF
23. Impact of Prior Antiplatelet Therapy on Outcomes After Endovascular Therapy for Acute Stroke
- Author
-
Couture, Marie, Finitsis, Stephanos, Marnat, Gaultier, Richard, Sébastien, Bourcier, Romain, Constant-dits-Beaufils, Pacôme, Dargazanli, Cyril, Arquizan, Caroline, Mazighi, Mikaël, Blanc, Raphaël, Eugène, François, Vannier, Stéphane, Spelle, Laurent, Denier, Christian, Touzé, Emmanuel, Barbier, Charlotte, Saleme, Suzana, Macian, Francisco, Rosso, Charlotte, Clarençon, Frédéric, Naggara, Olivier, Turc, Guillaume, Ozkul-Wermester, Ozlem, Papagiannaki, Chrysanthi, Viguier, Alain, Cognard, Christophe, Lebras, Anthony, Evain, Sarah, Wolff, Valérie, Pop, Raoul, Timsit, Serge, Gentric, Jean-Christophe, Bourdain, Frédéric, Veunac, Louis, Lapergue, Bertrand, Consoli, Arturo, Gory, Benjamin, and Sibon, Igor
- Abstract
Supplemental Digital Content is available in the text.
- Published
- 2021
- Full Text
- View/download PDF
24. Functional Outcome, Recanalization, and Hemorrhage Rates After Large Vessel Occlusion Stroke Treated With Tenecteplase Before Thrombectomy
- Author
-
Gerschenfeld, Gaspard, Smadja, Didier, Turc, Guillaume, Olindo, Stephane, Laborne, François-Xavier, Yger, Marion, Caroff, Jildaz, Gonçalves, Bruno, Seners, Pierre, Cantier, Marie, l'Hermitte, Yann, Aghasaryan, Manvel, Alecu, Cosmin, Marnat, Gaultier, Ben Hassen, Wagih, Kalsoum, Erwah, Clarençon, Frédéric, Piotin, Michel, Spelle, Laurent, Denier, Christian, Sibon, Igor, Alamowitch, Sonia, Chausson, Nicolas, Degos, Vincent, Sarov, Mariana, Legris, Nicolas, Chassin, Olivier, Soumah, Djibril, Altarcha, Tony, Imbernon, Carole, Renou, Pauline, Poli, Mathilde, Debruxelles, Sabrina, Sagnier, Sharmila, Rouanet, François, Liegey, Jean-Sebastien, Calvet, David, Baron, Jean-Claude, Bottin, Laure, Delorme, Stephen, Capron, Jean, Doukhi, Diana, Ghazanfari, Sam, Weisenburger, David, Lescieux, Edwige, Gariel, Florent, Barreau, Xavier, Menegon, Patrice, Tourdias, Thomas, Oppenheim, Catherine, Naggara, Olivier, Tuilier, Titien, Sourour, Nader, Sourour, Nader, Shotar, Eimad, Lenck, Stéphanie, Premat, Kévin, Blanc, Raphaël, Escalard, Simon, Fahed, Robert, Smajda, Stanislas, and Mazighi, Mikael
- Published
- 2021
- Full Text
- View/download PDF
25. Relevance of Brain Regions' Eloquence Assessment in Patients With a Large Ischemic Core Treated With Mechanical Thrombectomy
- Author
-
Kerleroux, Basile, Benzakoun, Joseph, Janot, Kévin, Dargazanli, Cyril, Eraya, Dimitri Daly, Ben Hassen, Wagih, Zhu, François, Gory, Benjamin, Hak, Jean-Francois, Perot, Charline, Detraz, Lili, Bourcier, Romain, Aymeric, Rouchaud, Forestier, Géraud, Marnat, Gaultier, Gariel, Florent, Mordasini, Pasquale, Seners, Pierre, Turc, Guillaume, Kaesmacher, Johannes, Oppenheim, Catherine, Naggara, Olivier, Boulouis, Gregoire, Fischer, Urs, Gralla, Jan, Mosimann, Pascal J, Arnold, Marcel, Meinel, Thomas R, Costalat, Vincent, Benali, Amel, Derraz, Imad, Lefevre, Pierre-Henri, Gascou, Grégory, Riquelme, Carlos, Bonafe, Alain, Le Bars, Emmanuelle, Moynier, Marinette, Barreau, Xavier, Berge, Jérôme, Menegon, Patrice, Tourdias, Thomas, Lucas, Ludovic, Sibon, Igor, Saleme, Suzanna, Mounayer, Charbel, Girard, Nadine, Bartoli, Jean-Michel, Brunel, Hervé, Testud, Benoit, Puech, Basile, Laksiri, Nadia, Robinet, Emmanuelle, Pelletier, Jean, Herbreteau, Denis, Bibi, Richard, Narata, Ana-Paula, Boustia, Fakhreddine, Maldonado, Igor, Cottier, Jean- Philippe, Gaudron, Marie, Annan, Mariam, Meder, Jean-François, Trystram, Denis, Rodriguez, Christine, Edjlali, Myriam, Desal, Hubert, Daumasduport, Benjamin, Lallinec, Vincent, Lenoble, Cédric, Alexandre, Pierre-Louis, Bracard, Serge, Anxionnat, René, Degrelle, Anne-Laure, Tonnelet, Romain, Lao, Liang, Richard, Sébastien, Humbertjean, Lisa, Mione, Gioia, and Labour, Jean Christophe
- Published
- 2021
- Full Text
- View/download PDF
26. Dissecazione delle arterie carotidee e vertebrali extracraniche
- Author
-
Bodiguel, E., Naggara, O., and Mas, J.-L.
- Abstract
Una dissecazione arteriosa cervicale deriva dal clivaggio della parete arteriosa da parte di un ematoma che può o meno comunicare con il lume arterioso attraverso una breccia intimale. La maggior parte delle dissecazioni è spontanea o si verifica dopo un trauma cervicale minore. Esse si traducono in sintomi e segni locali (cefalee, cervicalgie, segno di Claude Bernard-Horner, acufeni, paralisi di nervi cranici) e in manifestazioni ischemiche cerebrali, oculari o, anche, midollari. I segni locali spesso precedono le manifestazioni ischemiche e il ritardo varia da poche ore a qualche settimana. Il metodo diagnostico di riferimento è la risonanza magnetica (RM). Le indicazioni per il trattamento antitrombotico (antiaggregante o anticoagulante) non sono chiare. L’evoluzione avviene, il più delle volte, verso la normalizzazione o la stabilizzazione del lume arterioso entro 3 mesi in media. A 1 anno, circa l’80% delle dissecazioni è normalizzato o stabilizzato. Oltre le poche settimane della fase acuta, il rischio annuo di recidiva della dissecazione è basso (circa dell’1%).
- Published
- 2021
- Full Text
- View/download PDF
27. Une BETTER check-listIRM pour mieux différencier le léiomyosarcome du léiomyome atypique utérin
- Author
-
Kermarrec, Édith, Nougaret, Stéphanie, Bazot, Marc, Wahab, Cendos Abdel, Bekhouche, Asma, and Thomassin-Naggara, Isabelle
- Abstract
Le but de cet article est d’illustrer un acronyme diagnostique permettant aux radiologues de mieux différencier le léiomyosarcome utérin du léiomyome atypique en IRM pelvienne. Il a été présenté au congrès annuel 2018 de la Radiological Society of North America(RSNA) sous forme d’un poster réalisé par plusieurs experts internationaux qui ont proposé d’utiliser le mot BET1T2ER pour analyser plusieurs critères de suspicion de léiomyosarcome.
- Published
- 2021
- Full Text
- View/download PDF
28. Effect of Operator’s Experience on Proficiency in Mechanical Thrombectomy
- Author
-
Zhu, François, Ben Hassen, Wagih, Bricout, Nicolas, Kerleroux, Basile, Janot, Kevin, Gory, Benjamin, Anxionnat, René, Richard, Sébastien, Marchal, Adrien, Blanc, Raphael, Piotin, Michel, Consoli, Arturo, Trystram, Denis, Rodriguez Regent, Christine, Desilles, Jean-Philippe, Weisenburger-Lile, David, Escalard, Simon, Herbreteau, Denis, Ifergan, Heloise, Lima Maldonado, Igor, Labreuche, Julien, Henon, Hilde, Naggara, Olivier, Lapergue, Bertrand, and Boulouis, Grégoire
- Abstract
Supplemental Digital Content is available in the text.
- Published
- 2021
- Full Text
- View/download PDF
29. Impact of Repeated Clot Retrieval Attempts on Infarct Growth and Outcome After Ischemic Stroke
- Author
-
Ben Hassen, Wagih, Touloupas, Caroline, Benzakoun, Joseph, Boulouis, Gregoire, Bretzner, Martin, Bricout, Nicolas, Legrand, Laurence, Rodriguez, Christine, Le Berre, Alice, Seners, Pierre, Turc, Guillaume, Cordonnier, Charlotte, Oppenheim, Catherine, Henon, Hilde, and Naggara, Olivier
- Published
- 2021
- Full Text
- View/download PDF
30. TEMPORARY REMOVAL: MRI OF THE WALL OF UNRUPTURED INTRACRANIAL ANEURYSMS: IS ENHANCEMENT OF THE ANEURYSM WALL AFTER GADOLINIUM INJECTION A PREDICTIVE MARKER OF THE RISK OF ANEURYSMAL GROWTH?
- Author
-
TAT, Thomas LE, HUANG, Zack, EDJLALI, Myriam, TESSIER, Farha, GORTAIS, Hugo, HASSEN, Wagih BEN, RODRIGUEZ, Christine, TRYSTRAM, Denis, OPPENHEIM, Catherine, and NAGGARA, Olivier
- Published
- 2024
- Full Text
- View/download PDF
31. Teaching NeuroImage: Traumatic Dissection of Lenticulostriate Arteries Within an Enlarged Perivascular Space
- Author
-
Janvier, Paul, Kerleroux, Basile, Varlan, David, Rodriguez-Régent, Christine, Trystram, Denis, Allard, Julien, Drai, Maxime, Oppenheim, Catherine, Ben Hassen, Wagih, and Naggara, Olivier
- Abstract
A 33-year-old woman was admitted with right side hemiplegia after head trauma. Brain MRI revealed an acute ischemic stroke in the left lenticulostriate territory and a parenchymal hematoma (Figure 1). The hematoma occurred within an enlarged perivascular space (PVS), which had been incidentally discovered 10 years earlier.1,2It was suspected that a traumatic dissection of lenticulostriate arteries within the PVS was responsible for both ischemic and hemorrhagic events (Figure 1). Healing of the hematoma and disappearance of the PVS and the lenticulostriate arteries were observed 2 months later (Figure 2). Excessive mobility of lenticulostriate arteries within an enlarged PVS may explain the mechanism of traumatic dissection in this case.
- Published
- 2022
- Full Text
- View/download PDF
32. Hyperacute Recanalization Strategies and Childhood Stroke in the Evidence Age
- Author
-
Chabrier, Stéphane, Ozanne, Augustin, Naggara, Olivier, Boulouis, Grégoire, Husson, Béatrice, and Kossorotoff, Manoëlle
- Abstract
No controlled pharmacological studies are available in the field of pediatric stroke, except for sickle cell disease. Therefore, while pharmacological and mechanical recanalization treatments have repeatedly shown clinical benefit in adults with arterial ischemic stroke, pediatric strokologists still cannot base their therapeutic management (including hyperacute strategies) on high-level evidence. Once again, pediatricians face the same dichotomic choice: adapting adult procedures now versus waiting—for a long time—for the corresponding pediatric trials. One way out is building a compromise based on observational studies with large, longitudinal, comprehensive, real-life, and multisource dataset. Two recent high-quality observational studies have delivered promising conclusions on recanalization treatments in pediatric arterial ischemic stroke. TIPSTER (Thrombolysis in Pediatric Stroke Extended Results) showed that the risk of severe intracranial hemorrhage after intravenous thrombolysis is low; the Save Childs Study reported encouraging data about pediatric thrombectomy. Beyond the conclusion of a satisfactory global safety profile, a thorough analysis of the methods, populations, results, and therapeutic complications of these studies helps us to refine indications/contraindications and highlights the safeguards we need to rely on when discussing thrombolysis and thrombectomy in children. In conclusion, pediatric strokologists should not refrain from using clot lysis/retrieval tools in selected children with arterial ischemic stroke. But the implementation of hyperacute care is only feasible if the right candidate is identified through the sharing of common adult/pediatric protocols and ward collaboration, formalized well before the child’s arrival. These anticipated protocols should never undervalue contraindications from adult guidelines and must involve the necessary pediatric expertise when facing specific causes of stroke, such as focal cerebral arteriopathy of childhood.
- Published
- 2021
- Full Text
- View/download PDF
33. Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors
- Author
-
Bakker, Mark K., van der Spek, Rick A. A., van Rheenen, Wouter, Morel, Sandrine, Bourcier, Romain, Hostettler, Isabel C., Alg, Varinder S., van Eijk, Kristel R., Koido, Masaru, Akiyama, Masato, Terao, Chikashi, Matsuda, Koichi, Walters, Robin G., Lin, Kuang, Li, Liming, Millwood, Iona Y., Chen, Zhengming, Rouleau, Guy A., Zhou, Sirui, Rannikmäe, Kristiina, Sudlow, Cathie L. M., Houlden, Henry, van den Berg, Leonard H., Dina, Christian, Naggara, Olivier, Gentric, Jean-Christophe, Shotar, Eimad, Eugène, François, Desal, Hubert, Winsvold, Bendik S., Børte, Sigrid, Johnsen, Marianne Bakke, Brumpton, Ben M., Sandvei, Marie Søfteland, Willer, Cristen J., Hveem, Kristian, Zwart, John-Anker, Verschuren, W. M. Monique, Friedrich, Christoph M., Hirsch, Sven, Schilling, Sabine, Dauvillier, Jérôme, Martin, Olivier, Jones, Gregory T., Bown, Matthew J., Ko, Nerissa U., Kim, Helen, Coleman, Jonathan R. I., Breen, Gerome, Zaroff, Jonathan G., Klijn, Catharina J. M., Malik, Rainer, Dichgans, Martin, Sargurupremraj, Muralidharan, Tatlisumak, Turgut, Amouyel, Philippe, Debette, Stéphanie, Rinkel, Gabriel J. E., Worrall, Bradford B., Pera, Joanna, Slowik, Agnieszka, Gaál-Paavola, Emília I., Niemelä, Mika, Jääskeläinen, Juha E., von Und Zu Fraunberg, Mikael, Lindgren, Antti, Broderick, Joseph P., Werring, David J., Woo, Daniel, Redon, Richard, Bijlenga, Philippe, Kamatani, Yoichiro, Veldink, Jan H., and Ruigrok, Ynte M.
- Abstract
Rupture of an intracranial aneurysm leads to subarachnoid hemorrhage, a severe type of stroke. To discover new risk loci and the genetic architecture of intracranial aneurysms, we performed a cross-ancestry, genome-wide association study in 10,754 cases and 306,882 controls of European and East Asian ancestry. We discovered 17 risk loci, 11 of which are new. We reveal a polygenic architecture and explain over half of the disease heritability. We show a high genetic correlation between ruptured and unruptured intracranial aneurysms. We also find a suggestive role for endothelial cells by using gene mapping and heritability enrichment. Drug-target enrichment shows pleiotropy between intracranial aneurysms and antiepileptic and sex hormone drugs, providing insights into intracranial aneurysm pathophysiology. Finally, genetic risks for smoking and high blood pressure, the two main clinical risk factors, play important roles in intracranial aneurysm risk, and drive most of the genetic correlation between intracranial aneurysms and other cerebrovascular traits.
- Published
- 2020
- Full Text
- View/download PDF
34. Classification O-RADS US et IRM
- Author
-
Boisselier, Antonia, Jalaguier-Coudray, Aurélie, Mahjoub-Villard, Rim, and Thomassin-Naggara, Isabelle
- Abstract
L’Ovarian-Adnexal Imaging-Reporting Data System (O-RADS) stratifie le risque de malignité et oriente la prise en charge des masses annexielles. Les scores selon l'O-RADS Ultrasound (US) vont de 0 à 5 : 0 correspond à un examen incomplet, 1 à des images physiologiques, 2 est attribué à des masses typiquement bénignes, 3 à des masses probablement bénignes, 4 à des masses indéterminées nécessitant un complément d’imagerie et 5 à des masses suspectes de malignité. Les scores selon l’O-RADS IRM vont également de 1 à 5 : 1 correspond à l’absence de lésion annexielle, 2 à des lésions bénignes, 3 à des lésions probablement bénignes nécessitant un suivi, 4 à des lésions indéterminées et 5 à des lésions suspectes de malignité nécessitant une chirurgie.
- Published
- 2020
- Full Text
- View/download PDF
35. Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data
- Author
-
Thomalla, Götz, Boutitie, Florent, Ma, Henry, Koga, Masatoshi, Ringleb, Peter, Schwamm, Lee H, Wu, Ona, Bendszus, Martin, Bladin, Christopher F, Campbell, Bruce C V, Cheng, Bastian, Churilov, Leonid, Ebinger, Martin, Endres, Matthias, Fiebach, Jochen B, Fukuda-Doi, Mayumi, Inoue, Manabu, Kleinig, Timothy J, Latour, Lawrence L, Lemmens, Robin, Levi, Christopher R, Leys, Didier, Miwa, Kaori, Molina, Carlos A, Muir, Keith W, Nighoghossian, Norbert, Parsons, Mark W, Pedraza, Salvador, Schellinger, Peter D, Schwab, Stefan, Simonsen, Claus Z, Song, Shlee S, Thijs, Vincent, Toni, Danilo, Hsu, Chung Y, Wahlgren, Nils, Yamamoto, Haruko, Yassi, Nawaf, Yoshimura, Sohei, Warach, Steven, Hacke, Werner, Toyoda, Kazunori, Donnan, Geoffrey A, Davis, Stephen M, Gerloff, Christian, Acosta, Boris Raul, Aegidius, Karen, Albiker, Christian, Alegiani, Anna, Almendrote, Miriam, Alonso, Angelika, Althaus, Katharina, Amarenco, Pierre, Amiri, Hemasse, Anders, Bettina, Aniculaesei, Adriana, Appleton, Jason, Arenillas, Juan, Back, Christina, Bähr, Christian, Bardutzky, Jürgen, Baronnet-Chauvet, Flore, Bathe-Peters, Rouven, Bayer-Karpinska, Anna, Becerra, Juan L., Beck, Christoph, Belchí Guillamon, Olga, Benoit, Amandine, Berhoune, Nadia, Bindila, Daniela, Birchenall, Julia, Blanc-Lasserre, Karine, Blanco Gonzales, Miguel, Bobinger, Tobias, Bodechtel, Ulf, Bodiguel, Eric, Bojaryn, Urszula, Bonnet, Louise, Bouamra, Benjamin, Bourgeois, Paul, Boutitie, Florent, Breuer, Lorenz, Breynaert, Ludovic, Broughton, David, Brouns, Raf, Brugirard, Sébastian, Bruneel, Bart, Buggle, Florian, Cakmak, Serkan, Calleja, Ana, Calvet, David, Carrera, David, Chen, Hsin-Chieh, Cheng, Bastian, Cheripelli, Bharath, Cho, Tae-Hee, Choe, Chi-un, Choy, Lillian, Christensen, Hanne, Ciatipis, Mareva, Cloud, Geoffrey, Cogez, Julien, Cortijo, Elisa, Crozier, Sophie, Damgaard, Dorte, Dani, Krishna, De Coene, Beatrijs, De Hollander, Isabel, De Keyser, Jacques, De Klippel, Nina, De Maeseneire, Charlotte, De Smedt, Ann, del Mar Castellanos Rodrigo, Maria, Deltour, Sandrine, Demeestere, Jelle, Derex, Laurent, Desfontaines, Philippe, Dittrich, Ralf, Dixit, Anand, Dobbels, Laurens, Domigo, Valérie, Dorado, Laura, Druart, Charlotte, Dupont, Kristina Hougaard, Dusart, Anne, Dziewas, Rainer, Ebinger, Martin, Ebner, Matthias, Edjali-Goujon, Myriam, Eisele, Philipp, El Tawil, Salwa, Elhfnawy, Ahmed, Endres, Matthias, Etexberria, Ana, Evans, Nicholas, Fandler, Simon, Fazekas, Franz, Felix, Sandra, Fiebach, Jochen B., Fiehler, Jens, Filipov, Alexandra, Filipski, Katharina, Fleischmann, Robert, Foerch, Christian, Ford, Ian, Gaenslen, Alexandra, Galinovic, Ivana, Gancedo, Elena Meseguer, Ganeshan, Ramanan, García Esperón, Carlos, Garrido, Alicia, Gattringer, Thomas, Geraghty, Olivia, Geran, Rohat, Gerloff, Christian, Gerner, Stefan, Godon-Hardy, Sylvie, Göhler, Jos, Golsari, Amir, Gomis, Meritxell, Gorriz, David, Gramse, Verena, Grau, Laia, Griebe, Martin, Guerrero, Cristina, Guerzoglu, Damla, Guettier, Sophie, Guiraud, Vincent, Gumbinger, Christoph, Gunreben, Ignaz, Haertig, Florian, Hametner, Christian, Hanseeuw, Bernard, Hansen, Andreas, Hansen, Jakob, Harbo, Thomas, Harloff, Andreas, Harmel, Peter, Häusler, Karl Georg, Heinen, Florian, Held, Valentin, Hellwig, Simon, Hemelsoet, Dimitri, Hennerici, Michael, Herm, Juliane, Hermans, Sylvia, Hernández, María, Hervas Vicente, Jose, Hjort, Niels, Hobeanu, Cristina, Hobohm, Carsten, Höfner, Elmar, Hohenbichler, Katharina, Hommel, Marc, Hoppe, Julia, Hornberger, Eva, Hoyer, Carolin, Huang, Xuya, Ipsen, Nils, Isern, Irina, Ispierto, Lourdes, Iversen, Helle, Jeppesen, Lise, Jimenez, Marta, Jungehülsing, Jan, Jüttler, Eric, Kalladka, Dheeraj, Kallmünzer, Bernd, Kar, Arindam, Kellert, Lars, Kemmling, André, Kessler, Tobias, Khan, Usman, Klein, Matthias, Kleinschnitz, Christoph, Klockziem, Matti, Knops, Michael, Koehler, Luzie, Koehrmann, Martin, Kohlfürst, Heinz, Kollmar, Rainer, Kraft, Peter, Krause, Thomas, Kristensen, Bo, Kröber, Jan M., Kurka, Natalia, Ladoux, Alexandre, Laloux, Patrice, Lamy, Catherine, Landrault, Emmanuelle, Lauer, Arne, Lebely, Claire, Leempoel, Jonathan, Lees, Kennedy, Leger, Anne, Legrand, Laurence, Lemmens, Robin, Li, Lin, Löbbe, Anna-Mareike, London, Frederic, Lopez-cancio, Elena, Lorenz, Matthias, Louw, Stephen, Lovelock, Caroline, Lozano Sánchez, Manuel, Lucente, Giuseppe, Lückl, Janos, Luna, Alain, Macha, Kosmas, Machet, Alexandre, Mackenrodt, Daniel, Madzar, Dominik, Majoie, Charles, Männer, Anika, Maqueda, Vicky, Marstrand, Jacob, Martinez, Alicia, Marzina, Annika, Mechthouff, Laura, Meden, Per, Meersman, Guy, Meier, Julia, Mellerio, Charles, Menn, Oliver, Meyer, Nadja, Michalski, Dominik, Michels, Peter, Michelsen, Lene, Millán Torne, Monica, Minnerup, Jens, Modrau, Boris, Moeller, Sebastian, Møller, Anette, Morel, Nathalie, Moreton, Fiona, Morin, Ludovic, Moulin, Thierry, Moynihan, Barry, Mueller, Anne K., Muir, Keith W., Mulero, Patricia, Mundiyanapurath, Sibu, Mutzenbach, Johannes, Nagel, Simon, Naggara, Oliver, Nallasivan, Arumugam, Navalpotro, Irene, Nave, Alexander H., Nederkoorn, Paul, Neeb, Lars, Neugebauer, Hermann, Neumann-Haefelin, Tobias, Nighoghossian, Norbert, Oberndorfer, Stefan, Opherk, Christian, Oppel, Lorenz, Oppenheim, Catherine, Orthgieß, Johannes, Ostergaard, Leif, Paindeville, Perrine, Palomeras, Ernest, Panitz, Verena, Patel, Bhavni, Peeters, Andre, Peeters, Dirk, Pellisé, Anna, Pelz, Johann, Pereira, Anthony, Pérez de la Ossa, Natalia, Perry, Richard, Petraza, Salvador, Peysson, Stéphane, Pfeilschifter, Waltraud, Pichler, Alexander, Pierskalla, Alexandra, Pledl, Hans-Werner, Poli, Sven, Pomrehn, Katrin, Poulsen, Marika, Prats, Luis, Presas, Silvia, Prohaska, Elisabeth, Puetz, Volker, Puig, Josep, Puig Alcántara, Josep, Purrucker, Jan, Quenardelle, Veronique, Ramachandran, Sankaranarayanan, Raphaelle, Soulliard, Raposo, Nicolas, Reiff, Tilman, Remmers, Michel, Renou, Pauline, Ribitsch, Martin, Richter, Hardy, Ringleb, Peter, Ritter, Martin, Ritzenthaler, Thomas, Rodier, Gilles, Rodriguez-Regent, Christine, Rodríguez-Yáñez, Manuel, Roennefarth, Maria, Roffe, Christine, Rosenbaum, Sverre, Rosso, Charlotte, Röther, Joachim, Rozanski, Michal, Ruiz de Morales, Noelia, Russo, Francesca, Rutgers, Matthieu, Sagnier, Sharmilla, Samson, Yves, Sánchez, Josep, Sauer, Tamara, Schäfer, Jan H., Schieber, Simon, Schill, Josef, Schlak, Dennis, Schlemm, Ludwig, Schmidt, Sein, Schonewille, Wouter, Schröder, Julian, Schulz, Andreas, Schurig, Johannes, Schwarting, Sönke, Schwarz, Alexander, Schwarzbach, Christopher, Seidel, Matthias, Seiler, Alexander, Sembill, Jochen, Serena Leal, Joaquin, Shetty, Ashit, Sibon, Igor, Simonsen, Claus Z., Singer, Oliver, Sivagnanaratham, Aravinth, Smets, Ide, Smith, Craig, Soors, Peter, Sprigg, Nikola, Spruegel, Maximilian, Stark, David, Steinert, Susanne, Stösser, Sebastian, Stuermlinger, Markus, Swinnen, Bart, Tamazyan, Ruben, Tembl, Jose, Terceno Izaga, Mikel, Thijs, Vincent, Thomalla, Götz, Touze, Emmanuel, Truelsen, Thomas, Turc, Guillaume, Turine, Gaetane, Tütüncü, Serdar, Tyrell, Pippa, Ustrell, Xavier, Vadot, Wilfried, Vallet, Anne-Evelyne, Vallet, Pauline, van den Berg, Lucie, van den Berg, Sophie, van Eendenburg, Cecile, Van Hooff, Robbert-Jan, van Sloten, Isabelle, Vanacker, Peter, Vancaester, Evelien, Vanderdonckt, Patrick, Vandermeeren, Yves, Vanhee, Frederik, Veltkamp, Roland, Vestergaard, Karsten, Viguier, Alain, Vilas, Dolores, Villringer, Kersten, Voget, Dieke, von Schrader, Jörg, von Weitzel, Paul, Warburton, Elisabeth, Weber, Claudia, Weber, Jörg, Wegscheider, Karl, Wegscheider, Mirko, Weimar, Christian, Weinstich, Karin, Weise, Christopher, Weise, Gesa, Willems, Chris, Winder, Klemens, Wittayer, Matthias, Wolf, Marc, Wolf, Martin, Wolff, Valerie, Wollboldt, Christian, Wollenweber, Frank, Wouters, Anke, Yalo, Bertrand, Yger, Marion, Younan, Nadia, Yperzeele, Laetita, Zegarac, Vesna, Zeiner, Pia, Ziemann, Ulf, Zonneveld, Thomas, Zuber, Mathieu, Akutsu, Tsugio, Aoki, Junya, Aoki, Junya, Arakawa, Shuji, Doijiri, Ryosuke, Egashira, Yusuke, Enomoto, Yukiko, Fukuda-Doi, Mayumi, Furui, Eisuke, Furuta, Konosuke, Gotoh, Seiji, Hamasaki, Toshimitsu, Hasegawa, Yasuhiro, Hirano, Teryuki, Homma, Kazunari, Ichijyo, Masahiko, Ide, Toshihiro, Igarashi, Shuichi, Iguchi, Yasuyuki, Ihara, Masafumi, Ikenouchi, Hajime, Inoue, Manabu, Inoue, Tsuyoshi, Itabashi, Ryo, Ito, Yasuhiro, Iwama, Toru, Kamiyama, Kenji, Kamiyoshi, Shoko, Kanai, Haruka, Kanematsu, Yasuhisa, Kanzawa, Takao, Kimura, Kazumi, Kitayama, Jiro, Kitazono, Takanari, Koga, Masatoshi, Kondo, Rei, Kudo, Kohsuke, Kusumi, Masayoshi, Kuwahara, Ken, Matsumoto, Shoji, Matsuoka, Hideki, Mihara, Ban, Minematsu, Kazuo, Miura, Ken, Miwa, Kaori, Morita, Naomi, Mouri, Wataru, Murata, Kayo, Nagakane, Yoshinari, Nakase, Taizen, Ohara, Hiromi, Ohara, Nobuyuki, Ohnishi, Hideyuki, Ohta, Hajime, Ohtaki, Masafumi, Ohtani, Ryo, Ohtsuki, Toshiho, Ohyama, Hideo, Okada, Takashi, Okada, Yasushi, Osaki, Masato, Sakai, Nobuyuki, Sanbongi, Yoshiki, Sasaki, Naoshi, Sasaki, Makoto, Sato, Shoichiro, Seki, Kenta, Shimizu, Wataru, Shiokawa, Yoshiaki, Sozu, Takashi, Suzuki, Junichiro, Suzuki, Rieko, Takagi, Yasushi, Takizawa, Shunya, Tanahashi, Norio, Tanaka, Eijiro, Tanaka, Ryota, Tateishi, Yohei, Terada, Tomoaki, Terasaki, Tadashi, Todo, Kenichi, Tokunaga, Azusa, Toyoda, Kazunori, Tsujino, Akira, Ueda, Toshihiro, Uesaka, Yoshikazu, Uotani, Mihoko, Urabe, Takao, Watanabe, Masao, Yagita, Yoshiki, Yakushiji, Yusuke, Yamamoto, Haruko, Yasui, Keizo, Yonehara, Toshiro, Yoshimura, Sohei, Yoshimura, Shinichi, Aarnio, K., Alemseged, F., Anderson, C., Ang, T., Archer, M.L., Attia, J., Bailey, P., Balabanski, A., Barber, A., Barber, P.A., Bernhardt, J., Bivard, A., Blacker, D., Bladin, C.F., Brodtmann, A., Cadilhac, D., Campbell, B.C.V., Carey, L., Celestino, S., Chan, L., Chang, W.H., ChangI, A., Chen, C.H., Chen, C.-I., Chen, H.F., Chen, T.C., Chen, W.H., Chen, Y.Y., Cheng, C.A., Cheong, E., Chiou, Y.W., Choi, P.M., Chu, H.J., Chuang, C.S., Chung, T.C., Churilov, L., Clissold, B., Connelly, A., Coote, S., Coulton, B., Cowley, E., Cranefield, J., Curtze, S., D'Este, C., Davis, S.M., Day, S., Desmond, P.M., Dewey, H.M., Ding, C., Donnan, G.A., Drew, R., Eirola, S., Field, D., Frost, T., Garcia-Esperon, C., George, K., Gerraty, R., Grimley, R., Guo, Y.C., Hankey, G., Harvey, J., Ho, S.C., Hogan, K., Howells, D., Hsiao, P.M., Hsu, C.H., Hsu, C.T., Hsu, C.-S., Hsu, J.P., Hsu, Y.D., Hsu, Y.T., Hu, C.J., Huang, C.C., Huang, H.Y., Huang, M.Y., Huang, S.C., Huang, W.S., Jackson, D., Jeng, J.S., Jiang, S.K., Kaauwai, L., Kasari, O., King, J., Kleinig, T.J., Koivu, M., Kolbe, J., Krause, M., Kuan, C.W., Kung, W.L., Kyndt, C., Lau, C.L., Lee, A., Lee, C.Y., Lee, J.T., Lee, Y., Lee, Y.C., Levi, C., Levi, C.R., Lien, L.M., Lim, J.C., Lin, C.C., Lin, C.H., Lin, C.M., Lin, D., Liu, C.H., Liu, J., Lo, Y.C., Loh, P.S., Low, E., Lu, C.H., Lu, C.J., Lu, M.K., Ly, J., Ma, H., Macaulay, L., Macdonnell, R., Mackey, E., Macleod, M., Mahadevan, J., Maxwell, V., McCoy, R., McDonald, A., McModie, S., Meretoja, A., Mishra, S., Mitchell, P.J., Miteff, F., Moore, A., Muller, C., Ng, F., Ng, F.C., Ng, J-L., O'Brian, W., O'Collins, V., Oxley, T.J., Parsons, M.W., Patel, S., Peng, G.S., Pesavento, L., Phan, T., Rodrigues, E., Ross, Z., Sabet, A., Sallaberger, M., Salvaris, P., Shah, D., Sharma, G., Sibolt, G., Simpson, M., Singhal, S., Snow, B., Spratt, N., Stark, R., Sturm, J., Sun, M.C., Sun, Y., Sung, P.S., Sung, Y.F., Suzuki, M., Tan, M., Tang, S.C., Tatlisumak, T., Thijs, V., Tiainen, M., Tsai, C.H., Tsai, C.K., Tsai, C.L., Tsai, H.T., Tsai, L.K., Tseng, C.H., Tseng, L.T., Tsoleridis, J., Tu, H., Tu, H.T-H., Vallat, W., Virta, J., Wang, W.C., Wang, Y.T., Waters, M., Weir, L., Wijeratne, T., Williams, C., Wilson, W., Wong, A.A., Wong, K., Wu, T.Y., Wu, Y.H., Yan, B., Yang, F.C., Yang, Y.W., Yassi, N., Yeh, H.L., Yeh, J.H., Yeh, S.J., Yen, C.H., Young, D., Ysai, C.L., Zhang, W.W., Zhao, H., Zhao, L., Althaus-Knaurer, Katharina, Bendszus, Martin, Berrouschot, Jörg, Bluhmki, Erich, Bovi, Paolo, Chatellier, Gilles, Cove, Lynda, Davis, Stephen, Dixit, A., Donnan, Geoffrey, Dziewas, Rainer, Ehrenkrona, Christina, Eschenfelder, Christoph, Fatar, Marc, Francisco Arenillas, Juan, Gruber, Franz, Hacke, Werner, Kala, Lalit, Kapeller, Peter, Kaste, Markku, Kessler, Christof, Köhrmann, Martin, Laage, Rico, Lees, Kennedy R., Leys, Didier, Luna Rodriguez, Alain, Mas, Jean-Louis, Mikulik, Robert, Molina, Carlos, Muddegowda, Girish, Muir, Keith, Niederkorn, Kurt, Nuñez, Xavier, Oppenheim, Catherine, Poli, Sven, Ringleb, Peter, Schellinger, Peter, Schwab, Stefan, Serena, Joaquin, Sobesky, Jan, Steiner, Thorsten, Svenson, Ann-Sofie, Toni, Danilo, Veltkamp, Roland, von Kummer, Rüdiger, Wahlgren, Nils, Wardlaw, Joanna, Betensky, Rebecca A., Boulouis, Gregoire, Carandang, Raphael A., Copen, William A., Cougo, Pedro, Cutting, Shawna, Drake, Kendra, Ford, Andria L., Hallenbeck, John, Harris, Gordon J., Hoesch, Robert, Hsia, Amie, Kase, Carlos, Latour, Lawrence, Lauer, Arne, Lev, Michael H., Muzikansky, Alona, Nagaraja, Nandakumar, Schwamm, Lee H., Searls, Eric, Song, Shlee S., Starkman, Sidney, Warach, Steven, Wu, Ona, Yoo, Albert J., and Zand, Ramin
- Abstract
Patients who have had a stroke with unknown time of onset have been previously excluded from thrombolysis. We aimed to establish whether intravenous alteplase is safe and effective in such patients when salvageable tissue has been identified with imaging biomarkers.
- Published
- 2020
- Full Text
- View/download PDF
36. Outcome and recanalization rate of tandem basilar artery occlusion treated by mechanical thrombectomy
- Author
-
Elhorany, Mahmoud, Boulouis, Grégoire, Hassen, Wagih Ben, Crozier, Sophie, Shotar, Eimad, Sourour, Nader-Antoine, Lenck, Stephanie, Premat, Kevin, Fahed, Robert, Degos, Vincent, Elhfnawy, Ahmed Mohamed, Mansour, Ossama Yassin, Tag El-din, El-Sayed Ali, Fadel, Wael Ahmed, Alamowitch, Sonia, Samson, Yves, Naggara, Olivier, and Clarençon, Frédéric
- Published
- 2020
- Full Text
- View/download PDF
37. Mechanical thrombectomy practices in France: Exhaustive survey of centers and individual operators
- Author
-
Forestier, Géraud, Kerleroux, Basile, Janot, Kévin, Zhu, François, Dumas, Victor, Hak, Jean-François, Shotar, Eimad, Ben Hassen, Wagih, Bourcier, Romain, Soize, Sébastien, Berge, Jérome, Naggara, Olivier, Desal, Hubert, Boulouis, Grégoire, Rouchaud, Aymeric, Hanafi, R., L’Allinec, V., Girot, J.-B., Charbonnier, G., Biondi, A., Gariel, F., Marnat, G., Ognard, J., Gentric, J.-C., Barbier, C., Chabert, E., Lebedinsky, P., Tuilier, T., Thouant, P., Comby, P.-O., Mejdoubi, M., Heck, O., Kastler, A., Chalumeau, V., Caroff, J., Personnic, T., Marchal, A., Bogey, C., Eker, O., Carle, X., Dargazanli, C., Derraz, I., Gory, B., Detraz, L., Sedat, J., Zurlinden, O., Escalard, S., Fahed, R., Guedon, A., Civelli, V., Premat, K., Clarençon, F., Ducouret, E., Raynaud, N., Velasco, S., Manceau, P.-F., Paya, C., Eugene, F., Le Moa, J., Papagiannaki, C., Aggour, M., Bintner, M., Veyrieres, J.-B., Richter, J.S., Pop, R., Consoli, A., Di-Maria, F., Arteaga, C., Darcourt, J., Michelozzi, C., Guedin, P., Herbreteau, D., and Le Bras, A.
- Abstract
•The number of mechanical thrombectomies has increased a sevenfold since 2012 in France.•The mean number of interventional neuroradiologist per center performing mechanical thrombectomy increased from 2.9±0.9 to 3.7±1.85.•Majority of interventional neuroradiologist use combined (stent and distal aspiration) approach (54.5%), and the use of balloon guide catheter is not standard, with a third of them never using it.•The majority of centers performing mechanical thrombectomy would require at least one more interventional neuroradiologist to stabilize team and insure continuity of care.
- Published
- 2020
- Full Text
- View/download PDF
38. Diagnostic Algorithm to Differentiate Benign Atypical Leiomyomas from Malignant Uterine Sarcomas with Diffusion-weighted MRI
- Author
-
Abdel Wahab, Cendos, Jannot, Anne-Sophie, Bonaffini, Pietro A., Bourillon, Camille, Cornou, Caroline, Lefrère-Belda, Marie-Aude, Bats, Anne-Sophie, Thomassin-Naggara, Isabelle, Bellucci, Alexandre, Reinhold, Caroline, and Fournier, Laure S.
- Abstract
A diagnostic algorithm including diffusion-weighted MRI criteria may help even inexperienced readers distinguish uterine sarcoma from atypical leiomyoma.
- Published
- 2020
- Full Text
- View/download PDF
39. Résultats de la sclérothérapie percutanée à l’alcool dans le traitement des kystes osseux anévrysmaux de l’enfant et de l’adolescent
- Author
-
Marie-Hardy, Laura, El Sayed, Laila, Alves, Alexandra, Brunelle, Francis, Ouchrif, Younès, Naggara, Olivier, Breton, Sylvain, Mascard, Eric, Glorion, Christophe, and Pannier, Stéphanie
- Abstract
Les kystes osseux anévrysmaux (KOA) sont des lésions osseuses bénignes de l’enfant et de l’adolescent qui peuvent présenter un pouvoir agressif local avec un risque fracturaire et dont la nature et le traitement restent, encore aujourd’hui, discutés. Le but de cette étude est de vérifier l’efficacité, la simplicité et la bonne tolérance de la sclérothérapie percutanée à l’alcool absolu dans le traitement des KOA.
- Published
- 2020
- Full Text
- View/download PDF
40. Acute Stroke Management During the COVID-19 Pandemic
- Author
-
Hajdu, Steven D., Pittet, Valerie, Puccinelli, Francesco, Ben Hassen, Wagih, Ben Maacha, Malek, Blanc, Raphaël, Bracco, Sandra, Broocks, Gabriel, Bartolini, Bruno, Casseri, Tommaso, Clarençon, Frederic, Naggara, Olivier, Eugène, François, Ferré, Jean-Christophe, Guédon, Alexis, Houdart, Emmanuel, Krings, Timo, Lehmann, Pierre, Limbucci, Nicola, Machi, Paolo, Macho, Juan, Mandruzzato, Nicolo, Nappini, Sergio, Nawka, Marie Teresa, Nicholson, Patrick, Marto, João Pedro, Pereira, Vitor, Correia, Manuel A., Pinho-e-Melo, Teresa, Nuno Ramos, João, Raz, Eytan, Ferreira, Patrícia, Reis, João, Shapiro, Maksim, Shotar, Eimad, van Horn, Noel, Piotin, Michel, and Saliou, Guillaume
- Abstract
During the coronavirus disease 2019 (COVID-19) pandemic, the World Health Organization recommended measures to mitigate the outbreak such as social distancing and confinement. Since these measures have been put in place, anecdotal reports describe a decrease in the number of endovascular therapy (EVT) treatments for acute ischemic stroke due to large vessel occlusion. The purpose of our study was to determine the effect on EVT for patients with acute ischemic stroke during the COVID-19 confinement. In this retrospective, observational study, data were collected from November 1, 2019, to April 15, 2020, at 17 stroke centers in countries where confinement measures have been in place since March 2020 for the COVID-19 pandemic (Switzerland, Italy, France, Spain, Portugal, Germany, Canada, and United States). This study included 1600 patients treated by EVT for acute ischemic stroke. Date of EVT and symptom onset-to-groin puncture time were collected. Mean number of EVTs performed per hospital per 2-week interval and mean stroke onset-to-groin puncture time were calculated before confinement measures and after confinement measures. Distributions (non-normal) between the 2 groups (before COVID-19 confinement versus after COVID-19 confinement) were compared using 2-sample Wilcoxon rank-sum test. The results show a significant decrease in mean number of EVTs performed per hospital per 2-week interval between before COVID-19 confinement (9.0 [95% CI, 7.8–10.1]) and after COVID-19 confinement (6.1 [95% CI, 4.5–7.7]), (P<0.001). In addition, there is a significant increase in mean stroke onset-to-groin puncture time (P<0.001), between before COVID-19 confinement (300.3 minutes [95% CI, 285.3–315.4]) and after COVID-19 confinement (354.5 minutes [95% CI, 316.2–392.7]). Our preliminary analysis indicates a 32% reduction in EVT procedures and an estimated 54-minute increase in symptom onset-to-groin puncture time after confinement measures for COVID-19 pandemic were put into place.
- Published
- 2020
- Full Text
- View/download PDF
41. Prediction of Unruptured Intracranial Aneurysm Evolution: The UCAN Project
- Author
-
L’Allinec, Vincent, Chatel, Stéphanie, Karakachoff, Matilde, Bourcereau, Emmanuelle, Lamoureux, Zeineb, Gaignard, Alban, Autrusseau, Florent, Jouan, Solène, Vion, Anne-Clemence, Loirand, Gervaise, Desal, Hubert, Naggara, Olivier, Redon, Richard, Edjlali, Myriam, and Bourcier, Romain
- Published
- 2020
- Full Text
- View/download PDF
42. Cryoablation percutanée de l’endométriose en radiologie interventionnelle
- Author
-
Najdawi, Milan, Ben Ammar, Mohamed, Nouri-Neuville, Maud, Barral, Matthias, Kermarrec, Édith, Thomassin-Naggara, Isabelle, and Cornelis, François H.
- Abstract
La radiologie interventionnelle propose des traitements minimalement invasifs guidés par l’image. De nombreux actes peuvent être réalisés en alternative ou complément des traitements médicaux ou chirurgicaux de l’endométriose proposés jusqu’à présent, notamment la cryoablation percutanée. Le guidage précis permet de minimiser les risques de complications pour les patientes tout en améliorant l’efficacité de la cryoablation. L’expertise du radiologue interventionnel reste cruciale pour garantir le succès.
- Published
- 2020
- Full Text
- View/download PDF
43. Increased Wall Enhancement During Follow-Up as a Predictor of Subsequent Aneurysmal Growth
- Author
-
Gariel, Florent, Ben Hassen, Wagih, Boulouis, Grégoire, Bourcier, Romain, Trystram, Denis, Legrand, Laurence, Rodriguez-Regent, Christine, Saloner, David, Oppenheim, Catherine, Naggara, Olivier, and Edjlali, Myriam
- Abstract
Supplemental Digital Content is available in the text.
- Published
- 2020
- Full Text
- View/download PDF
44. Stratégies ganglionnaires dans les cancers de l’endomètre
- Author
-
Owen, Clémentine, Bendifallah, Sofiane, Jayot, Aude, Ilenko, Anna, Arfi, Alexandra, Boudy, Anne Sophie, Richard, Sandrine, Varinot, Justine, Thomassin-Naggara, Isabelle, Bazot, Marc, and Daraï, Émile
- Abstract
En 2018, dans le monde, près de 382 100 nouveaux cas de cancer de l’endomètre ont été recensés, ce qui représente environ 4,4 % des nouveaux cas de cancer chez la femme. En France, en 2018, le cancer de l’endomètre est le premier cancer gynécologique en incidence et le quatrième cancer chez la femme. Le rationnel de la prise en charge thérapeutique du cancer de l’endomètre repose sur l’estimation d’un risque théorique de récidive et de métastase ganglionnaire sur des critères IRM et biopsique préopératoire. Cependant, le statut ganglionnaire reste l’élément déterminant du traitement adjuvant. Afin de diminuer la morbidité de la lymphadénectomie, le concept du ganglion sentinelle a été développé. La technique du ganglion sentinelle a évolué ces dernières années grâce à l’avènement de la robotique et la création de caméra à détection de fluorescence. Il a été montré que la détection du ganglion sentinelle au Vert d’Indocyanine (ICG) permettait une migration bilatérale plus fréquente de 88 à 100 % et une meilleure détection des ganglions sentinelles pelviens dans 97 % des cas avec une baisse de la morbidité. Récemment, devant l’absence de rôle thérapeutique de la stadification ganglionnaire, les risques opératoires et le décalage des traitements adjuvants en cas de métastase ganglionnaire pelvienne à l’examen histologique définitif, la question de réaliser secondairement la lymphadénectomie lombo-aortique se pose. La procédure du ganglion sentinelle élargie à l’ensemble des cancers de l’endomètre de stade précoce devrait aboutir à une réduction majeure du recours à une stadification secondaire et une meilleure adaptation de la thérapeutique adjuvante.
- Published
- 2020
- Full Text
- View/download PDF
45. Nouvelles recommandations pour le bilan des masses annexielles indéterminées
- Author
-
Bekhouche, Asma, Pottier, Edwige, Abdel Wahab, Cendos, Milon, Audrey, Kermarrec, Édith, Bazot, Marc, and Thomassin-Naggara, Isabelle
- Abstract
L’IRM, du fait de sa spécificité, a une place prépondérante pour la caractérisation des masses annexielles. Pour permettre une prise en charge adaptée, et notamment éviter des chirurgies extensives inutiles et détecter des lésions à haute probabilité de malignité, une standardisation des protocoles et des comptes rendus est nécessaire. Le protocole d’IRM doit comporter au minimum une séquence axiale T2 abdominopelvienne, une séquence sagittale T2, une séquence axiale T1 sans et avec saturation du signal de la graisse, une séquence axiale de diffusion, une séquence T1 avec saturation du signal de la graisse après injection dynamique de gadolinium et une séquence T1 avec saturation du signal de la graisse après injection tardive de gadolinium. La conclusion du compte rendu doit comporter un score diagnostique (« Ovarian-adnexal Imaging-Reporting-Data System [O-Rads] IRM version 1 » ; ancienne dénomination : Adnex MR) et éventuellement une ou plusieurs hypothèse(s) anatomopathologique(s). Ces recommandations sont issues des travaux coordonnées par le Collège des gynécologues obstétriciens (CNGOF) et de l'Institut national du cancer (INCa) et ont été validées par la Société d'imagerie de la femme (Sifem).
- Published
- 2020
- Full Text
- View/download PDF
46. Dépistage et diagnostic du cancer du sein à la fin de période de confinement COVID-19, aspects pratiques et hiérarchisation des priorités
- Author
-
Ceugnart, Luc, Delaloge, Suzette, Balleyguier, Corinne, Deghaye, Michel, Veron, Lucie, Kaufmanis, Aldis, Mailliez, Audrey, Poncelet, Edouard, Lenczner, Gregory, Verzaux, Laurent, Gligorov, Joseph, and Thomassin-Naggara, Isabelle
- Published
- 2020
- Full Text
- View/download PDF
47. Risques et sécurité de l’imagerie mammaire chez la femme enceinte et en cours d’allaitement
- Author
-
Kermarrec, Édith, Gardavaud, François, Kerrou, Khaldoun, Bekhouche, Asma, Wahab, Cendos Abdel, Milon, Audrey, and Thomassin-Naggara, Isabelle
- Abstract
Pendant la grossesse et l’allaitement, l’échographie mammaire est l’examen de première intention. En cas de pathologie suspecte, la stratégie diagnostique est difficile car nécessite la réalisation d’imageries avancées à risque pour le fœtus. L’état actuel de la littérature ne permet pas de donner de recommandations claires quant au bilan d’extension du cancer du sein lié à la grossesse et celui-ci doit être adapté au rapport bénéfice–risque maternofœtal selon le type histologique et le risque métastatique du cancer. Les imageries nécessaires devront être discutées et validées en comité multidisciplinaire d’experts. L’objectif de cet article est de sensibiliser les radiologues aux risques et à la sécurité des examens d’imagerie mammaire pendant la grossesse et l’allaitement.
- Published
- 2020
- Full Text
- View/download PDF
48. MT-DRAGON score for outcome prediction in acute ischemic stroke treated by mechanical thrombectomy within 8 hours
- Author
-
Ben Hassen, Wagih, Raynaud, Nicolas, Bricout, Nicolas, Boulouis, Gregoire, Legrand, Laurence, Ferrigno, Marc, Kazemi, Apolline, Bretzner, Martin, Soize, Sebastien, Farhat, Wassim, Seners, Pierre, Turc, Guillaume, Zuber, Mathieu, Oppenheim, Catherine, Cordonnier, Charlotte, Naggara, Olivier, and Henon, Hilde
- Abstract
ObjectivesThe MRI-DRAGON score includes clinical and MRI parameters and demonstrates a high specificity in predicting 3 month outcome in patients with acute ischemic stroke (AIS) treated with intravenous tissue plasminogen activator (IV tPA). The aim of this study was to adapt this score to mechanical thrombectomy (MT) in a large multicenter cohort.MethodsConsecutive cases of AIS treated by MT between January 2015 and December 2017 from three stroke centers were reviewed (n=1077). We derived the MT-DRAGON score by keeping all variables of the MRI-DRAGON score (age, initial National Institutes of Health Stroke Scale score, glucose level, pre-stroke modified Rankin Scale (mRS) score, diffusion weighted imaging-Alberta Stroke Program Early CT score ≤5) and considering the following variables: time to groin puncture instead of onset to IV tPA time and occlusion site. Unfavorable 3 month outcome was defined as a mRS score >2. Score performance was evaluated by c statistics and an external validation was performed.ResultsAmong 679 included patients (derivation and validation cohorts, n=431 and 248, respectively), an unfavorable outcome was similar between the derivation (51.5%) and validation (58.1%, P=0.7) cohorts, and was significantly associated with all MT-DRAGON parameters in the multivariable analysis. The c statistics for unfavorable outcome prediction was 0.83 (95%CI 0.79 to 0.88) in the derivation and 0.8 (95%CI 0.75 to 0.86) in the validation cohort. All patients (n=55) with an MT-DRAGONscore ≥11 had an unfavorable outcome and 60/63 (95%) patients with an MT-DRAGON score ≤2 points had a favorable outcome.ConclusionThe MT-DRAGON score is a simple tool, combining admission clinical and radiological parameters that can reliably predict 3 month outcome after MT.
- Published
- 2020
- Full Text
- View/download PDF
49. Small vessel disease in patients with subarachnoid hemorrhage: Prevalence and associations with vasospasm occurrence, severity and clinical outcomes
- Author
-
Villain, Adrien, Boulouis, Grégoire, Ben Hassen, Wagih, Rodriguez-Regent, Christine, Trystram, Denis, Edjlali, Myriam, Nataf, François, Sauvageon, Xavier, Sharshar, Tarek, Meder, Jean F, Oppenheim, Catherine, and Naggara, Olivier
- Abstract
Purpose Investigating the associations between cerebral small vessel disease (cSVD) burden and cerebral vasospasm (CVS), delayed cerebral ischemia (DCI) and clinical outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH).Methods Consecutive aSAH patients with initial (<7 days after onset) and 3-month follow-up brain magnetic resonance imaging (MRI) and clinical evaluation at 6 months were included. The cSVD burden score was built using MRI criteria. CVS was defined according to transcranial Doppler examination and computed tomography (CT) or digital subtraction angiography. DCI was defined by the appearance of hyperintense fluid-attenuated inversion recovery lesions, with territorial or cortico-subcortical distribution, between initial MRI and 3-month MRI. The modified Rankin scale of ≤2 at 6 months was considered a favorable outcome. Using univariate and multivariable analyses, we investigated the associations between cSVD and CVS, DCI and clinical outcome.Results A total of 113 patients were included in the study sample (median age 49.1 years (IQR 42.1–60.8), 70/113 females). The burden of cSVD was mild with a median of 0 (IQR 0–1). When comparing patients with no/mild versus those with moderate/severe cSVD burden, we did not find a univariable difference regarding vasospasm occurrence (60% versus 46.1%, p= 0.54), DCI (20.2% versus 23%, p= 0.66) or favorable outcome at 3 months (94% versus 83.3%, p= 0.20). There was a univariable trend towards more frequent favorable outcome in patients with no/milde white matter hyperintensities versus those with moderate/severe white matter hyperintensities (92% versus 85%, p = 0.09). In multivariable models, cSVD markers were not associated with CVS occurrence and severity, DCI or clinical outcome.Conclusions In patients with mild aSAH, the burden of cSVD as assessed by MRI is minimal and is not associated with CVS, DCI or clinical outcome.
- Published
- 2019
- Full Text
- View/download PDF
50. Nouvelle classification et recommandation de prise en charge du cancer du col de l’utérus selon la Fédération internationale de gynécologie obstétrique (FIGO)
- Author
-
Bekhouche, Asma, Pottier, Edwige, Wahab, Cendos Abdel, Milon, Audrey, Kermarrec, Édith, Bazot, Marc, and Thomassin-Naggara, Isabelle
- Abstract
De grands progrès ont été réalisés pour réduire l’augmentation de l’incidence du cancer du col utérin. Dans plus de 80 pays, la vaccination contre le papillomavirus est maintenant incluse dans les programmes nationaux de vaccination. Le dépistage a également vu des avancées majeures avec la mise en œuvre des tests pour l’infection par le papillomavirus à plus grande échelle. Cependant, ces interventions prendront quelques années à montrer leur impact. Actuellement, l’incidence du cancer du col utérin est de plus d’un demi-million de nouveaux cas par an. Les développements récents en imagerie et le recours accru à la chirurgie mini-invasive ont changé le paradigme pour la prise en charge de ces cas. Le comité d’oncologie gynécologique de la Fédération internationale de gynécologie obstétrique a révisé le système de stadification du cancer du col utérin sur la base de ces avancées. Cet article présente cette nouvelle classification.
- Published
- 2019
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.