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High comfort and low energy consumption communities have become an important topic for community planning & design in China. Considering the special situation in China, the meaning of high comfort and low energy consumption communities lies in three aspects: making utmost use of natural climatic conditions, providing enjoyable indoor and outdoor living environments in circumstances of high-rise and high-density development, and holistic design of adjacent dwelling units to provide utmost flexibility. This paper uses design proposals for two real projects in two different cities in China - one in Yixing in South China and another one in Harbin in north China - as examples of how to design high comfort and low energy consumption communities by following local climatological factors and by respecting occupants’ needs in the long run. This paper shows that such communities can be planned in two steps, with special attention to the local climate. First, climatically responsive site planning determines building layout, height of each part, and also the design of open spaces. Second, detailed planning & design addresses the disadvantages of the site, improving space quality. Following local climatological conditions is also one of the key issues in housing design for high comfort & low energy consumption communities. In the housing design of the Harbin project, besides consideration to climate, special attention was also given to flexible/variable dwelling unit design according to occupants’ long-term needs. The “1+1 mode” is put forward to provide utmost flexibility for families with 3 generations for their current and future lives.

Abstract: Monoclonal antibody 3H11 was labelled with99mTc by modified Schwartz method. The antibody was incubated in a glass test tube at room temperature for 30min with a 1000-fold molar excess of 2-mercaptoethanol. The mean labelling efficiency of 3H11 with99mTc was more than 95%. The immuonreactivity of99mTc-3H11 was more than 80% by ELISA's method. Competetion results in vitro and HPLC analysis showed that99mTc was combined at the high affinity sites of antibody. The biodistribution in nude mice bearing 823 gastric cancer xenograpfts showed that the radioactivity in tumor at 24h postinjection was the highest except for that in kidney. The tumor uptake was 8.98±2.42% i.d/g. The ratio of tumor to blood was over 1.5 and that of tumor to liver was more than 2.5 at 24h post-injection. The tumor was clearly imaged at 22h postinjection. The inital clinical results showed that99mTc-3H11 was stable in vivo and was good located at the lesion sites.

Abstract: To investigate the radioimmunotherapeutic efficacy, radio-immunoconjugate131-I-3G9,311-I-3H11 and131-I-NMIgG (irre levant antibody) were i.p. injected into nude mice bearing human gastric cancer xenograftes. Each animal received a single doses of 5.55MBq. Over 14 days the accumulative absorbed doses in tumors were 13.7 Gy for131-I-3H11 and 12.17 Gy for131-I-3G9. Both were significantly higher than that for131-I-NMIgG (3.23 Gy). Thera peutic efficacy appeared most sharply from 2 to 3 weeks after injection. The inhibition ratio of tumor were 86% and 70% for131-I-3H11 and131-I-3G9 respectively. Histopathological evidance indicated that in tumor tissues radioactive damage was showed as karyopyknosis, karyorrhexis and necrosis or partial disappearance of tumor cells, while in the other tissues no radioactive damage was observed. WBC counts of all animals did not show significant difference before and after treatment, which indicat ed that the haemopoietic function of bone marrow was not affected.