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Introduction:Primary oral melanoma is an uncommon malignant tumor that originates from the proliferation of melanocytes. Case Presentation:A 78‐year‐old man presented with a pigmented lesion around the maxillary anterior implant prosthesis. The lesion was excised and diagnosed as a melanoma. Biopsy showed a malignant pigmented neoplasm that included proliferation of dysplastic melanocytes into the superficial layers of the submucosa. Initial testing, including a positron emission tomography scan, showed no metastasis; however, after 7 months, the patient developed a cervical lymphadenopathy. A neck dissection was performed and indicated that there was metastasis of the primary melanoma. After surgery, the patient received chemotherapy. Conclusions:Histologic examination of the excised lesion revealed the presence of a malignant melanoma in association with a junctional nevus of the oral mucosa. The patient was referred to the oral and maxillofacial department for further evaluation.

A 26-year-old physically challenged man with a history of 7 months’ infection and pus discharge was referred to the oral and maxillofacial department. He had undergone right mandibular teeth extraction 1 year ago, which was followed by pus discharge from an extraoral submandibular fistula after 2 months. Again, incision and drainage and wide-spectrum antibiotic were prescribed, which subsided the symptoms for a short period but did not cure the condition. So, sequestrectomy, complete debridements, and antibiotic therapy were planned for him. In the operating room, it was revealed that the sequestrum was the condylar process, and in follow-up cone-beam computed tomography scan, the condyle was being regenerated simultaneously. One-year follow-up showed successful treatment of the condition.

Aneurismal bone cyst (ABC) is a rare bony lesion occurring predominantly in long bones. Its jaws’ involvement is uncommon and the simultaneous involvement of both jaws is very rare. This report is about a 27-year-old female experiencing renal failure with ABC involving her maxilla and mandible. The progressive lesion was treated surgically and there was no recurrence after 18 months of follow-up.