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【目的】緊急の血液透析（HD）を要した高マグネシウム（Mg）血症症例の特徴について検討した。【対象】24年間に当院で高Mg血症により緊急HDを施行した15例とした。【結果】年齢の中央値は78（59–94）歳で，65歳以上が14例であった。男性6例，女性9例で，高Mg血症に起因しない入院中の死亡を2例に認めた。血清Mg値の中央値は6.0（3.7–18.6）mg/dLであった。HD前の臨床症状は意識障害を10例，血圧低下を5例，徐脈を5例，呼吸不全を2例に認めた。酸化マグネシウム（MgO）製剤を全例で内服しており，1日投与量は常用量である2.0g以下が12例，2.1g以上が2例，不明が1例であった。HD前の血清Cre値の中央値は5.39（0.54–10.29）mg/dLで，2例は上昇していなかった。急性腎障害（AKI）の合併は9例に認めた｡【結語】当院で緊急HDを要した高Mg血症症例の多くは，常用量のMgO製剤を内服中の高齢者であった。腎機能低下は高Mg血症の危険因子であり，AKIの合併例を多く認めたが，発症時血清Cre値が上昇していない症例もあった。このためMgO製剤を内服中の高齢者が意識障害，血圧低下，徐脈，呼吸不全などで救急外来を受診した際は，MgO製剤の投与量や血清Cre値に関わらず高Mg血症の可能性を考え，血清Mg値を測定する必要がある。 Aims: This study aimed to clarify the characteristics of patients who presented with severe hypermagnesemia and subsequently underwent emergency hemodialysis. Methods: We investigated the age, gender, background, symptoms, causal drugs, electrocardiogram findings and laboratory data of 15 patients. Results: Magnesium oxide had been administered in all cases and 14 patients were over 65–year–old. The male–to–female ratio was 6–to–9. Chief complaints included a disturbance of consciousness, hypotension, bradycardia and respiratory failure. The median serum magnesium concentration was 6.0 (3.7–18.6)mg/dL. The daily dosage of magnesium oxide was lower than 2.0g in 12 cases. The median serum creatinine concentration before hemodialysis was 5.39 (0.54–10.29)mg/dL. However, in 2 cases the creatinine concentration was not elevated. Complications of acute kidney injury exacerbated the hypermagnesemia in 9 cases. Conclusions: We recommend that the serum magnesium concentration should be measured in older patients who are taking magnesium oxide and are showing signs and symptoms of disturbance of consciousness, hypotension, bradycardia and respiratory failure of an uncertain etiology, even if the serum creatinine concentration is not elevated or the dosage of magnesium oxide is within recommended levels.

We report on the measurement of coherent radio emission from the electron beam sudden appearance at the Telescope Array Electron Light Source facility. This emission was detected by four independent radio detector setups sensitive to frequencies ranging from 50 MHz up to 12.5 GHz. We show that this phenomenon can be understood as a special case of coherent transition radiation by comparing the observed results with simulations. The in-nature application of this signal is given by the emission of cosmic ray or neutrino induced particle cascades traversing different media such as air, rock and ice. [ABSTRACT FROM AUTHOR]