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1. Interferon gamma autoantibodies associated with susceptibility to disseminated mycobacterial infections

Author

Bosco, J., Nicholls, K., McComish, J., Bleasel, K., Unglik, G., Choo, S., Flanagan, K., Fulcher, D., Naselli, G., Martinuzzi, E., and Harrison, L.

Abstract

Disseminated non-tuberculous mycobacterial (NTM) infections typically occur in the context of iatrogenic immunosuppression or inherited genetic mutations. Rarely, cytokine-specific autoantibodies have also been described in patients with disseminated infections. Here, we present two cases of disseminated NTM infection in unrelated healthy adult females associated with autoantibodies to interferon-gamma (IFN-γ).

Published
2014
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