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1. Assessment of Early Radiation-Induced Changes in Left Ventricular Function by Myocardial Strain Imaging After Breast Radiation Therapy

Author

Yu, Anthony F., Ho, Alice Y., Braunstein, Lior Z., Thor, Maria E., Lee Chuy, Katherine, Eaton, Anne, Mara, Elton, Cahlon, Oren, Dang, Chau T., Oeffinger, Kevin C., Steingart, Richard M., and Liu, Jennifer E.

Abstract

Radiation therapy (RT)-induced cardiotoxicity is among the concerning sequelae of breast cancer (BCA) treatment, particularly in HER2-positive BCA patients who receive anthracyclines and trastuzumab-based therapy. The aim of this study was to assess for early RT-induced changes in echocardiographic and circulating biomarkers of left ventricular (LV) function and evaluate their association with radiation dose to the heart among patients with HER2-positive BCA treated with contemporary RT.

Published
2019
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