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AbstractDoes ideological polarization undermine or strengthen people’s principled support for democracy? In this study, we suggest that different manifestations of ideological polarization have different implications in this respect. Using data from 11 surveys conducted with representative samples of the adult populations of a group of liberal democratic countries, part of the Comparative National Elections Project, we look at how people’s level of ideological extremism and their perceptions of ideological polarization in their countries’ party systems are related with their support for democracy. We show that citizens who hold more extreme ideological positions are indeed less supportive of democracy and that such a negative relationship is strengthened as citizens’ extremism increases. However, we also show that the citizens who display higher levels of principled support for democracy are those who perceive parties to be neither too distant nor too close to each other in ideological terms. In other words, while a very polarized partisan supply seems to undermine popular commitment with democracy, very low polarization may have similar consequences.

•SARS-CoV-2 Spike protein (Spk) induces intestinal chloride secretion in mice;•Spk causes lysozymes depletion by Paneth cells degranulation;•Spk diminishes mucus blanket associated with mucin 2 reduction;•Mucosal intestinal barrier is impaired by Spk inoculation on the gut;•Spk triggers local inflammation and dysmotility on the gut.

The austerity policies pursued in several countries during the Eurozone crisis began to call attention to the role played by courts as relevant actors in the context of budgetary and financial stress. The case of the Portuguese Constitutional Court has often been singled out in national and international forums as one characterized by particularly intense activism in this respect. Allegedly, political conflict around austerity policies and the demand for their judicial review had fundamentally changed the role of the Portuguese Constitutional Court and the behavior of its judges. However, after examining these claims empirically, we find that, when properly assessed with scrutiny of comparable legislation in other periods, the judicial behavior on austerity policies exhibits a much less exceptional pattern than often argued. Constitutional review in Portugal seems to respond to institutional arrangements (i.e., those fostering a central role for ideological preferences and party loyalty) and not to specific business cycles.