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A recent report from the University of Basel in Switzerland discusses the use of isothermal microcalorimetry (IMC) as a fast and reliable diagnostic tool for bacterial infections in veterinary medicine. The researchers examined 124 urine samples from cats and dogs with urinary tract infections and found that the IMC technology showed good performance in detecting Escherichia coli and Enterococcus faecalis bacteria. Compared to traditional culture methods, IMC had a diagnostic sensitivity of 80% and a diagnostic specificity of 97%. The researchers concluded that implementing IMC technology could significantly speed up the bacteriological diagnostic process in veterinary medicine. [Extracted from the article]

A recent study conducted at the University of Alabama at Birmingham has found that isothermal microcalorimetry (IMC) is a more accurate and faster method for detecting periprosthetic joint infection (PJI) after total joint arthroplasty compared to conventional cultures. The study collected deep tissue samples from 152 patients undergoing hip/knee arthroplasty and compared the results of IMC and cultures. The results showed that IMC had a sample concordance of 90% with cultures and demonstrated a sensitivity of 83% and specificity of 100% for PJI detection. IMC also had a significantly shorter median time to detection (TTD) compared to cultures. The study suggests that IMC can improve the accuracy and time to detection of PJI, particularly in patients on chronic antibiotics. [Extracted from the article]

In the spot test, EOP andoptical density assay, all cocktails and single phages lysed bothmethicillin susceptible and methicillin resistant S. aureus strains. Gram-Positive Bacteria - Staphylococcus aureus New study results on Staphylococcus aureus have been published. [Extracted from the article]

The article presents an interview with Esther Takeuchi who is an inventor. Topics include her work on the development of medical batteries used for cardiac defibrillators implanted in patients and to extend the lifetime of batteries; her joint appointments at Stony Brook University and Brookhaven National Laboratory; and use of tool such as isothermal microcalorimetry, for measurement of the heat that a battery generates.

The article discusses the three main methods for calorimetry used to measure exothermic and endothermic reactions during biological processes. These calorimetry methods include differential scanning calorimetry (DSC), isothermal calorimetry (ITC), and flow microcalorimetry (FMC). It indicates that a specific method to be used should be selected based on the reaction to be studies and information required.