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This article proposes a novel approach for predicting concrete compressive strength using deep learning techniques. It overcomes limitations of traditional methods like memory footprint, training time, and computational requirements for predicting concrete compressive strength. Currently various filter pruning techniques are used to compress models by removing irrelevant information, but they cannot decrease memory consumption due to their large parameters. So, the entropy-based filter pruning is suggested to reduce the complexity of the model by decreasing the parameters. Then for training the CNN model, the modified resilient backpropagation technique (MRPROP) is suggested, because the previous backpropagation techniques take more time for training and also it loss the accuracy. This MRPROP improve the efficiency and convergence of CNN training and also it updates the models weight. The proposed approach demonstrated superior performance in mean squared error, root mean squared error, loss function, and regression analysis, as per the experimental results.

The purpose of this paper is to report on a new system-theoretic based methodology and corresponding model for Enterprise Architecture development. This model captures the essence of the strategic, conceptual, doctrinal layer of the organization. Reusable Quality Technical Architectures (RQ-Tech) graphically reveals a comprehensive array of enterprise decision alternatives in easily understandable views; all while maintaining the hyperlinks to its provenance in strategic authoritative documentation. The RQ-Tech method has combined the practice of Enterprise Architectures with a modern perspective grounded in Systems Theory and the theory regarding the computer science-oriented Semantic Web. This recombination results in a distinctive methodology for developing models. This new methodology supports the conclusion that system-specific solutions produce islands of technology and can be prevented by employing better enterprise change planning. A review of the literature in three major areas illustrates the overlap common to all three domains. This review provides support for critical thinking concerning how to enrich the Enterprise Architecture practice. The research centered on finding the most significant factors to consider when translating the authoritative text and rich pictures that enterprise managers use to describe the strategic mission and vision of their complex, service-oriented enterprise into user-oriented semantic models. It provides the basis for RQ-Tech as a methodology that enables increased understanding of complex systems through use of Semantic Web standards.

Slowing aging is a widely shared goal. Plant-derived polyphenols, which are found in commonly consumed food plants such as tea, cocoa, blueberry and grape, have been proposed to have many health benefits, including slowing aging. In-vivo studies have demonstrated the lifespan-extending ability of six polyphenol-containing plants. These include five widely consumed foods (tea, blueberry, cocoa, apple, pomegranate) and a flower commonly used as a folk medicine (betony). These and multiple other plant polyphenols have been shown to have beneficial effects on aging-associated changes across a variety of organisms from worm and fly to rodent and human.

On 27 January 2011, the British Coalition Government launched a consultation on the future of the Public Forest Estate in England. Less than a month later beset by protest, it changed its mind. What are the implications of this policy vortex for conservation? What are the prospects for England's forests? [ABSTRACT FROM AUTHOR]

Small amounts of genetically foreign cells (microchimerism, Mc) traffic between a mother and fetus during pregnancy. Commonly, these grafts durably persist. For women, multiple naturally acquired Mc grafts can accrue, as they harbor Mc from their own mothers (maternal Mc, MMc) and subsequently acquire fetal Mc (FMc) through pregnancy. The nature of interactions between these naturally acquired grafts may inform, and be informed by, observations in transplantation, including the effect of noninherited maternal HLA antigens (NIMA) and double-unit cord blood transplantation (CBT). We asked whether FMc and MMc are impacted by the addition of new grafts as evaluated by increasing parity. Mc was identified by quantitative PCR for a nonshared polymorphism unique to the Mc source. Despite increasing sources of Mc, FMc did not increase with increasing parity. MMc concentration was significantly lower with increasing parity. The odds ratio for detection of MMc for 2 or more births compared with 1 birth was .11 (95% CI 0.03-0.42, P= .001). These observations suggest that interactions occur among naturally acquired grafts and are of interest in light of recent observations of graft-graft interaction resulting in predominance of 1 unit in double-unit CBT and the correlation of MMc with the NIMA effect.

Despite considerable research and the application of screening programs during the past three decades, the incidence of canine hip dysplasia (CHD) remains disturbingly high. Mild CHD is underdiagnosed by subjective evaluation of adult dogs, and moderate CHD is underdiagnosed by subjective assessment of immature dogs. Coxofemoral subluxation measurement methods hold promise for increasing the accuracy of CHD assessment, especially in 4-month-old dogs. Many radiologists have greater confidence in the PennHip method than in subjective hip assessment alone for dogs 6 months of age or younger. The incidence of CHD is unlikely to be dramatically reduced until CHD registries are open to the public and CHD examination is required for purebred dog registration.

When an individual harbors small amount of cells or DNA from another person, it is referred to as microchimerism (Mc). During pregnancy, Mc occurs naturally as the result of trafficking of cells both from the mother to the fetus and from the fetus to the mother. Maternal Mc (MMc) is the situation in which an individual carries cells from his or her own mother, which he or she acquired as a fetus. The reverse situation is fetal Mc (FMc), which occurs when fetal cells enter the maternal circulation during pregnancy. Both MMc and FMc can persist for years as “graft” cells. Thus a pregnant woman may harbor cells both from her own mother (which she acquired as a fetus) and from her offspring (which she acquired during pregnancy). Although multiparous women would be expected to acquire new sources of FMc during each gestation, and thus to display more FMc as compared with those who have had only a single pregnancy, the effect of multiparity on Mc is not completely known.

Purpose. Describe nutrition education at US colleges of osteopathic medicine; determine if it meets recommended levels. Method. We surveyed 30 US colleges of osteopathic medicine (US COM) with a four-year curriculum about the amount and form of required nutrition education during the 2012/13 academic year. The online survey asked about hours of required nutrition across all 4 years and also in what types of courses this instruction occurred. We performed descriptive statistics to analyze the data. Results. Twenty-six institutions (87% response rate) completed the survey. Most responding US COM (22/26, 85%) do not meet the recommended minimum 25 hours of nutrition education; 8 (31%) provide less than half as much. Required nutrition instruction is largely confined to preclinical courses, with an average of 15.7 hours. Only 7 of the 26 responding schools report teaching clinical nutrition practice, providing on average 4.1 hours. Conclusions. Most US COM are inadequately preparing osteopathic physicians for the challenges they will face in practice addressing the nutritional concerns of their patients. Doctors of osteopathy cannot be expected to properly treat patients or guide the prevention of cardiovascular disease, obesity, cancer, diabetes, and metabolic syndrome if they are not trained to identify and modify the contributing lifestyle factors.

Purpose. To assess the state of nutrition education at US medical schools and compare it with recommended instructional targets. Method. We surveyed all 133 US medical schools with a four-year curriculum about the extent and type of required nutrition education during the 2012/13 academic year. Results. Responses came from 121 institutions (91% response rate). Most US medical schools (86/121, 71%) fail to provide the recommended minimum 25 hours of nutrition education; 43 (36%) provide less than half that much. Nutrition instruction is still largely confined to preclinical courses, with an average of 14.3 hours occurring in this context. Less than half of all schools report teaching any nutrition in clinical practice; practice accounts for an average of only 4.7 hours overall. Seven of the 8 schools reporting at least 40 hours of nutrition instruction provided integrated courses together with clinical practice sessions. Conclusions. Many US medical schools still fail to prepare future physicians for everyday nutrition challenges in clinical practice. It cannot be a realistic expectation for physicians to effectively address obesity, diabetes, metabolic syndrome, hospital malnutrition, and many other conditions as long as they are not taught during medical school and residency training how to recognize and treat the nutritional root causes.

Various substrates can be successfully transformed to the corresponding aldehydes or ketones.