8 results on '"Karamanos B"'
Search Results
2. The ORlistat and CArdiovascular risk profile in patients with metabolic syndrome and type 2 DIAbetes (ORliCARDIA) study
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Didangelos, T. P., Thanopoulou, A. K., Bousboulas, S. H., Sambanis, C. L., Athyros, V. G., Spanou, E. A., Dimitriou, K. C., Pappas, S. I., Karamanos, B. G., and Karamitsos, D. T.
- Abstract
SUMMARYBackground:Metabolic syndrome (MetSyn) is associated with a marked increase in the risk of cardiovascular disease, especially in patients with type 2 diabetes mellitus (DM).Aim:To investigate the effect of orlistat plus hypocaloric diet (HCD) vs HCD alone on the cardiovascular risk profile in patients with both MetSyn (National Cholesterol Educational Program – NCEP – Adult Treatment Panel III definition) and type 2 DM.Methods:This was a prospective, multicentre, open-label, randomized, controlled study. One hundred and twenty-six patients, free of cardiovascular disease at baseline, were included in the final analysis. Ninety-four (73) patients were treated with orlistat (360 mg/day) and HCD for a 6-month period, while 34 (27) were on HCD alone. Analysis of covariance was used to assess differences between the treatment groups over time.Main outcome measures:Components of the MetSyn criteria assessed were: waist circumference; systolic and diastolic blood pressure; fasting glucose, triglycerides; high-density lipoprotein cholesterol (HDL-C) plus body mass index; glycosylated haemoglobin (HbA1C); homeostasis model for assessment of insulin resistance (HOMA) index; and total and low-density lipoprotein cholesterol (LDL-C).Results:By protocol, all patients had MetSyn at baseline. After a 6 month treatment period there were significant differences between the orlistat plus HCD vs the HCD-alone groups in body weight ( p 0.0001), waist circumference ( p< 0.0001), fasting glucose ( p< 0.0001), HbA1C( p< 0.0001), systolic blood pressure ( p 0.024), total cholesterol ( p< 0.0001), LDL-C ( p 0.034), and HOMA index ( p 0.022), while there were no significant differences in triglycerides and HDL-C. Orlistat was well tolerated. By the end of the study, 65 of the patients on orlistat plus HCD were still meeting the MetSyn criteria and 41 had four to five MetSyn components vs 91 ( p< 0.0001) and 53 ( p 0.017), respectively, of those on HCD alone.Conclusions:Orlistat plus HCD favourably modified several cardiovascular risk factors in patients with both MetSyn and type 2 DM. These effects might partly offset the excess cardiovascular risk and improve outcome in this patient population.
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- 2004
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3. Retinopathy and Vision Loss in Insulin-dependent Diabetes in Europe
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Sjølie, Anne Katrin, Stephenson, Judith, Aldington, Steve, Kohner, Eva, Janka, Hans, Stevens, Lynda, Fuller, John, Karamanos, B., Tountas, C., Kofinis, A., Petrou, K., Katsilambros, N., Cignarelli, M., Giorgino, R., Cignarelli, M., De Geco, M.L., Ramunni, I., Ionescu-Tirgoviste, C., Iosif, C.M., Pitei, C., Buligescu, S., Tamas, G., Kerenyi, Z., Ahmed, A.M., Toth, J., Kempler, P., Muntoni, S., Songini, M., Stabilini, M., Fossarello, M., Pintus, S., Ferriss, B., Cronin, C.C., Toeller, M., Klischan, A., Forst, T., Gries, F.A., Rottiers, R., Priem, H., Ebeling, P., Sinisalo, M., Koivisto, V.A., Idzior-Walus, B., Solnica, B., Szopinska-Ciba, L., Solnica, K., Krans, H.M.J., Lemkes, H.H.P.J., Jansen, J.J., Nunes-Cornea, J., Boavida, J., Michel, G., Wirion, R., Boulton, A.J.M., Ashe, H., Fernando, D.J.S., Pozza, G., Slaviero, G., Comi, G., Fattor, B., Bandello, F., Mehnert, H., Nuber, A., Janka, H., Ben Soussan, D., Fallas, M.C., Fallas, P., Jepson, E., McHardy-Young, S., Fuller, J.H., Betteridge, D.J., Milne, M., Crepaldi, G., Nosadini, R., Cathelineau, G., Villatte Cathelineau, B., Jellal, M., Grodner, N., Gervais Feiss, P., Santeusanio, F., Rosi, G., Ventura, M.R.M., Cagini, C., Marino, C., Navalesi, R., Penno, G., Miccoli, R., Nannipieri, M., Manfredi, S., Ghirlanda, G., Cotroneo, P., Manto, A., Teodonio, C., Minnella, A., Ward, J.D., Tesfaye, S., Mody, C., Rudd, C., Molinatti, G.M., Vitelli, F., Porta, M., Pagano, G.F., Cavallo Perin, P., Estivi, P., Sivieri, R., Carta, Q., Petraroli, G., Papazoglou, N., Manes, G., Triantaphyllou, G., Ioannides, A., Muggeo, M., Cacciatori, V., Bellavere, F., Galante, P., Gemma, M.L., Irsigler, K., Abrahamian, H., Gurdet, C., Hornlein, B., Willinger, C., Walford, S., Wardle, E.V., Roglic, G., Resman, Z., Metelko, Z., and Skrabalo, Z.
- Abstract
Purpose:To assess the frequency of retinopathy and vision loss in patients with insulin-dependent diabetes mellitus and their relations to potentially modifiable risk factors.
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- 1997
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4. Effect of the Long-Acting Somatostatin Analogue SMS 201-995 on the Glycaemic Control in Insulin-Treated Diabetics
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Karamanos, B., Tolis, G., Zoupas, C., Kardoyiannis, T., Benroubi, M., Alivisatos, J., and Yotis, A.
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- 1986
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5. Nutritional intake of 2868 IDDM patients from 30 centres in Europe
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Toeller, M., Klischan, A., Heitkamp, G., Schumacher, W., Milne, R., Buyken, A., Karamanos, B., and Gries, F. A.
- Abstract
The EURODIAB IDDM Complications Study, a cross-sectional, clinic-based study, was designed to measure the prevalence of diabetic complications in stratified samples of European insulin-dependent diabetic (IDDM) patients. As diet may be related to diabetic complications, nutritional intake was analysed in the study population. The aims of this first nutritional paper are to describe the nutrient intake in 2868 IDDM patients from 30 centres in 16 countries throughout Europe, to investigate the degree of regional differences in nutrient intake and to compare current intakes with recommended levels. Nutritional intake from 1458 male and 1410 female IDDM patients was assessed by a validated 3-day record (two weekdays, Sunday) and centrally analysed. Mean energy intake for all patients was 2390±707 kcal/day. Mean protein intake was 1.5±0.5 g/kg body weight. Carbohydrate intake was 43% and fibre intake 18 g/day. Alcohol intake for the total cohort was 2% of energy. Total fat contributed 38% of energy, with 14% from saturated fat. The Italian centres reported lower total and saturated fat intakes compared with other centres. Recommendations from the Diabetes and Nutrition Study Group of the EASD for total fat, saturated fatty acids and carbohydrate were only achieved by 14%, 14% and 15% of patients, respectively. The data of the present study clearly indicate current problems in the nutritional intake of European IDDM patients. These findings contribute to the definition of future targets in the nutritional management of IDDM patients, to be achieved as part of the initiatives taken by the St. Vincent Declaration action programme.
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- 1996
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6. Tenth Annual Meeting of the European Association for the Study of Diabetes
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Alberti, K., Iversen, J., Christensen, N., Andersson, A., Jarrousse, Claire, Andersson, Arne, Hellerström, Claes, Andreani, D., Tamburrano, G., Tamburrano, S., Gambardella, S., Ardill, Joy, Montgomery, D., Hadden, D., Assan, R., Attali, J., Selmi, A., Bourdillat, N., Soufflet, E., Girard, J., Bajaj, J., Chinna, G., Garg, S., Singh, Baldev, Balasse, E., Neef, M., Beischer, W., Melani, F., Keller, L., Hinz, M., Kroder, A., Maier, V., Pfeiffer, E., Bendayan, M., Sandborn, E., Rasio, E., Bensoussan, D., Levy-Toledano, S., Passa, P., Caen, J., Berger, M., Goodman, M., Hagg, S., Ruderman, N., Beyer, J., Cordes, U., Travniczek, H., Heider, W., Schöffling, K., Happ, J., Grimm, H., Pünchera, W., Althoff, P., Fröhlich, A., Bianco, A., Schwartz, R., Handwerger, B., Blackshear, P., Holloway, P., Williamson, D., Boquist, L., Hellman, Bo, Lernmark, Åke, Täljedabl, Inge-Bert, Bottermann, P., Schweigart, U., Zilker, Th., Hansen, W., Brachet, E., Rogister, C., Broer, Y., Freychet, P., Rosselin, G., Brunengraber, H., Vertongen, F., Boutry, M., Camu, F., Christacopoulos, P., Karamanos, B., Papadimitriou, P., Kardatos, Ch., Christensen, Niels, Neubauer, Bent, Christophe, Jean, Winand, Jacques, Dehaye, Jean, Cuendet, G., Loten, E., Jeanrenaud, B., Davis, E., Yodaiken, Ralph, Yanko, L., Herman, J., Garcia, S., Jarrousse, C., Ditzel, J., Daugaard, Niels, Andersen, Haakon, Egeberg, J., Nerup, J., Andersen, O., Kromann, H., Bendixen, G., Poulsen, J., Eschwege, E., Falkmer, S., Emdin, S., Havu, N., Biuw, L., Sundby, F., Cutfield, J., Cutfield, S., Dodson, G., Peterson, J., Steiner, D., Fallucca, F., Menzinger, G., Iavicoli, M., Federspil, G., de Palo, C., Zago, E., Casara, D., Zaccaria, M., Scandellari, C., Felber, J., Magnenat, G., Curchod, B., Pittet, Ph., Lytras, N., Müller-Hess, R., Geser, C., Jéquier, E., Flanagan, R., Buchanan, K., Murphy, R., Fölling, Ivar, Fromantin, M., Freyria, J., Bressac, F., Geisthövel, W., Niedergerke, U., Morgner, K., Willms, B., Mitzkat, H., Gey, K., Bühler, E., Sommer, P., Gey, K., Georgi, H., Sommer, P., Lengsfeld, H., Ghiea, D., Costiner, E., Simionescu, L., Oprescu, M., Grill, V., Cerasi, E., Gundersen, H., Gutman, A., Adler, J., Bar-Or, D., Gutzeit, A., Cerasi, E., Guy-Grand, B., Bigorie, B., Gylfe, Erik, Idahl, Lars-Åke, Hamosh, Margit, Hamosh, Paul, Hart, Adrian, Cohen, H., Thorp, J., Hedeskov, C., Capito, K., Forruby, B., Henquin, J., Lambert, A., Lambert, A., Henquin, J., Hepp, K., Renner, R., Häring, H., Mehnert, H., Kemmler, W., Löffler, G., Mehnert, H., Herchuelz, A., Mahy, M., Herrera, Emilip, Garcia-Rafanell, J., Morell, J., Heuclin, Ch., Attali, J., Girard, J., Assan, R., Hicks, B., Taylor, C., Vij, S., Pek, S., Knopf, R., Floyd, J., Fajans, S., Hockaday, T., Hockaday, J., Mann, J., Turner, R., Hockaday, T., Honour, A., Ikeda, Y., Saito, S., Matsuura, Y., Obayashi, N., Morimoto, Y., Sano, T., Abe, M., Jacouot, R., Felix, J., Legrele, C., Sutter-Dub, M., Sutter, B., Kammerer, L., Fehér, J., Lévai, J., Dénes, R., Stützel, M., Balázsi, I., Láng, I., Littmann, L., Karakash, C., Assimacopoulos, F., Katsilambros, N., Papadopoulos, G., Varonos, D., Daikos, G., Keen, H., Jarrett, R., Fuller, J., Kiesselbach, N., Puls, W., Keup, U., Kikkawa, Ryuichi, Duvillard, D., Ravazzola, M., Stauffacher, W., Köbberling, J., Kattermann, R., Kobberling, J., Creutzfeldt, W., Kohner, Eva, Hamilton, A., Joplin, G., Blach, R., Fraser, T., Kolb, H., Weiss, L., Wieland, O., Korn, A., Waldhäusl, W., Bonelli, J., Magometsohnigg, D., Hitzenberger, G., Kramp, Robert, Kremer, G., Atzpodien, W., Schnellbacher, B., Krug, B., Mialhe, P., Gross, R., Landgraf, R., Landgraf-Leurs, M., Klingenburg, M., Melamed, I., Hörl, R., Jun, István, Littmann, László, Stützel, Mária, Balázsi, Imre, Langslow, Derek, Buchanan, Keith, Freeman, Barry, Berezin, Meir, Mincu, I., Dumitrescu, C., Ionescu-Tirgoviste, C., Mihalache, N., Boboia, D., Stanescu, J., Ghise-Beer, E., Georgescu, St., Bruckner, I., Popa, I., Muggeo, M., Tiengo, A., Padovan, D., Molinari, M., Müller, Walter, and Sharp, Geoffrey
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- 1974
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7. Seventh Annual Meeting of the European Association for the Study Of Diabetes Southampton, England, September 15–17, 1971 Abstacts, Part 1
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Aboulker, J. P., Valleron, A. J., Papoz, L., Rathery, M., Adams, P. W., Munday, M. J., Oakley, N. W., Wynn, V., Andreani, D., Fallucca, F., Stirati, G., Tamburrano, G., Cinotti, G. A., Andreev, D., Tarkolev, N., Ditzov, S., Pencev, I., Ancreev, D., Sirskov, L., Arnold, R., Creutzfeldt, C., Deuticke, U., Frerichs, H., Track, N. S., Creutzfeldt, W., Asmal, A. C., Butterfieid, W. J. H., Karamanos, B., Whichelow, M. J., Butterfield, W. J. H., Cox, B. D., Ashcroft, S. J. H., Bassett, J. M., Randle, P. J., Asplund, K., Hellerström, C., Brolin, S. E., Berne, C., Edwards, John C., Petersson, B., Taylor, K. W., Assan, R., Hanoune, J., Attali, J. B., Tchobroutsky, G., Gross, G., Assimacopoulos, F., Orci, L., Rouiller, Ch., Jeanrenaud, B., Cameron, D. P., Amherdt, M., Mira, F., Stauffacher, W., Heindel, J. J., Cushman, S. W., Austoni, M., Federspil, G., Casara, D., Sieolo, N., Scandellari, C., Mastrogiacomo, I., Aynsley-Green, A., Alberti, K. G. M. M., Bacanu, Gh., Stoichescu, L., Nistor, F., Turcanu, V., Anghelescu, L., Bacchus, R. A., Meade, L. G., London, D. R., Baiasse, E. O., Barta, L., Brooser, G., Molnár, Maria, Belfiore, F., Vecchio, L. Lo, Napoli, E., Beyer, J., Cordes, U., Sell, G., Krall, N., Schöffling, K., Biebuyck, J. F., de Haan, B. Bierens, Scherrer, J. R., Pometta, D., Björntorp, P., Sjöström, L., Blach, R. K., Cheng, Hung, Bloom, S. R., Bojanowicz, K., Boquist, L., Brachet, E., Bruni, B., Capra, E., Büber, V., Felber, J. P., Buchanan, K. D., Connon, J. J., Buckle, R. M., Campeami, S., Campeanu, L., Ionesou, M., Cerasi, E., Luft, R., Efendic, S., Chabot, V., Gomez, F., Chiumello, G., del Guercio, M. J., Carnelutti, M., Christensen, Niels Juel, Iversen, J., Christiansen, Aa. Hein, Rasmussen, S. Munkgaard, Vø1und, Aa., Vólund, Aa., Clausen, T., Czyzyk, A., Szadkowski, M., Rogala, H., Lawecki, J., Davies, W. H., Martin, L. B., Mills, J. G., Vardey, C. J., Deckert, T., Lauridsen, U. Birk, Linde, J., Madsen, S. Nistrup, De Leeuw, I., Middelheim, A. Z., de Mowbray, R. R., Turner, J. J., Garner, S. D., Bruck, E., Nye, L., Triggs, S., Devlin, J. G., Varma, M., Kuti, J., Dumitrescu, C., Bolea-Feldman, M., Eschwege, E., Warnet, J. M., Richard, J. L., Menzinger, G., Javicoli, M., Fankhauser, S., Michl, J., Piemonte, G., Sicolo, N., Frezzato, S., Reffo, G. C., Luyckx, A., Lefebvre, P., Zaccaria, M., De Palo, C., Fernandes-Cruz, A., Lopiz-Quijada, C., Fernandez-Cruz, A., Otero, M. Luque, Fiedler, H., Hahn, H. J., Ziegler, Brigitte, Ziegler, M., Jutzi, E., Michael, R., Fischer, U., Hommel, H., Bibergeil, H., Förster, O., Rippel, W., Rudas, B., Franckson, J. R. M., Vanroux, R., Leclercq, R., Brunengraber, H., Ooms, H., Freytag, G., Klöppel, G., Fussgänger, R. D., Goberna, R., Schröder, K. E., Laube, H., Pfeiffer, E. F., Gazzola, G. C., Franchi, R., Ronchi, P., Saibene, E., Guidotti, G. G., Geldermans, C., Terpstra, J., Krans, H. M. J., Geser, C. A., Rattenhuber, E., Girard, J., Bal, D., Gligore, V., Mosora, N., Fekete, T., Beraru, T., Pipilian, V. V., Olteanu, L., Serban, A., Calusera, I., Holan, T., Miclutia, M., Gnudi, A., Coscelli, C., Ballerio, G., Palmari, V., Alpi, O., Cavazzini, G., Jéquier, E., Goth, E., Fövenyi, J., Hegedüs, A., Greco, A. V., Ghirlanda, G., Fedeli, G., Fenici, R., Gambassi, G., Grüneklee, D., Hessing, J., Daweke, H., Herberg, L., Gries, F. A., Guder, W., Wieland, O., Guillon, J., Bodic, L., Charbonnel, B., Hadden, D. R., Montgomery, D. A. D., Mayne, Elizabeth, Weaver, J. A., George, E, Hahn, J., Richter, O., Steinhilber, S., Kerp, L., Heaney, S. J., Varma, S. K., Whyte, W. G., Walker, R. S., Hepp, K. D., Hellman, B., Lernmark, A., Sehlin, J., Täljedal, I. -B., Hinz, M., Katsilambros, N., Rahman, Y. Abdel, Schatz, H., Maier, V., Schröder, B., Howells, D. P. M., Jackson, R. A., Perry, G., Rogers, J., Advani, U., Jafflol, C., Baldet, L., Vierne, Y., Mirouze, J., Jansen, F. K., Jarrett, R. J., Keen, H., Kaeding, A., Kaffarnik, H., Heink, U., Gassel, W. D., Zöfel, P., Mylarch, K., Keller, U., and Froesch, E. R.
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- 1971
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8. British Diabetic Association Abstracts
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Gumaa, K. A., Mclean, P., Kissebah, A. H., Galton, D. J., Fraser, T. Russell, Watson, I. G., Hokaday, T. D. R., Asmal, A. C., Butterfield, W. J. H., Cox, B. D., Karamanos, B., Whichelow, M. J., Richardson, J. F., Silverstone, Trevor, Besser, Michael, Brook, C. G. D., Thord, J. M., Hart, A., Cohen, H., Szanto, S., Yudkin, John, Fosbrooke, Audrey S., Lloyd, June K., Mowat, Joyce, Bewsher, P. D., Stowers, J. M., Ross, S. K., Dale, R. E. G., Thomson, W. S. T., Ireland, J. T., and Lawlor, T.
- Published
- 1971
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