7 results on '"Kakar, Puneet"'
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2. Prestroke Disability Predicts Adverse Poststroke Outcome
- Author
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Han, Thang S., Fry, Christopher H., Gulli, Giosue, Affley, Brendan, Robin, Jonathan, Irvin-Sellers, Melanie, Fluck, David, Kakar, Puneet, Sharma, Sapna, and Sharma, Pankaj
- Published
- 2020
- Full Text
- View/download PDF
3. Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
- Author
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Al-Shahi Salman, Rustam, Dennis, MS, Sandercock, PAG, Sudlow, CLM, Wardlaw, JM, Whiteley, WN, Murray, GD, Stephen, J, Newby, DE, Sprigg, N, Werring, DJ, White, PM, Baigent, Colin, Lasserson, Daniel, Sullivan, Frank, Carrie, Johanna, Rojas, Javier, Amoils, Shannon, Bamford, John, Armitage, Jane, Rinkel, Gabriel, Lowe, Gordon, Emberson, Jonathan, Innes, Karen, Dinsmore, Lynn, Drever, Jonathan, Williams, Carol, Perry, David, McGill, Connor, Buchanan, David, Walker, Allan, Hutchison, Aidan, Matthews, Christopher, Fraser, Ruth, McGrath, Aileen, Deary, Ann, Anderson, Rosemary, Walker, Pauli, Hansen, Christian, Parker, Richard, Rodriguez, Aryelly, Macleod, MR, Gattringer, Thomas, Palmer, Jeb, Sakka, Eleni, Adil-Smith, Jennifer, Minks, David, Mitra, Dipayan, Bhatnagar, Priya, du Plessis, Johannes, Joshi, Yogish, Lerpiniere, Christine, O'Brien, Richard, Burgess, Seona, Mead, Gillian, Paulton, Ruth, Doubal, Fergus, McCormick, Katrina, Hunter, Neil, Taylor, Pat, Parakramawansha, Ruwan, Perry, 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Martin, Irene, Hunt, Benjamin, Hassan, Hardi, O'Toole, Sarah, Dallol, Bander, Putterill, Janet, Jha, Ratneshwari, Gallifent, Rachel, Kakar, Puneet, Pusalkar, Aparna, Chan, Kelly, Dangri, Puneet, Beadle, Hannah, Cook, Angela, Crabtree, Karen, Subramonian, Santhosh, Owusu-Agyei, Peter, Temple, Natalie, Butterworth-Cowin, Nicola, Ragab, Suzanne, Knops, Kerstin, Jinks, Emma, Dickson, Christine, Gleave, Laura, Dube, Judith, Leggett, Jacqui, Garcia, Tatiana, Ispoglou, Sissy, Evans, Rachel, Ankolekar, Sandeep, Hayes, Anne, Ni, Hlaing, Rahman, Bithi, Milligan, Josette, Graham, Carol, Jose, Josin, Keegan, Breffni, Doherty, Mandy, Kelly, Jim, Blair, Caroline, Dewar, Richard, White, James, and Thomas, Kelly
- Abstract
Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events.
- Published
- 2019
- Full Text
- View/download PDF
4. Impact of delay in early swallow screening on pneumonia, length of stay in hospital, disability and mortality in acute stroke patients
- Author
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Han, Thang, Lean, Michael, Fluck, David, Affley, Brendan, Gulli, Giosue, Patel, Tasmin, Barrett, Christopher, Kakar, Puneet, Sharma, Sapna, and Sharma, Pankaj
- Abstract
Early swallow screening, within 4 h of admission, is required for all acute stroke patients to commence nutritional support, as recommended. We evaluated the impact of delay in early swallow screening on outcomes in patients admitted with acute stroke. Prospective cohort study of 1656 men (mean ± SD age = 73.1y ± 13.2) and 1653 women (79.3y ± 13.0) admitted with stroke to hyperacute stroke units (HASUs) in Surrey. Logistic regression was used to assess the risk (adjusted for age, stroke severity and co-morbidities) of delay in swallow screening on pneumonia, length of stay (LOS) > 3 weeks in HASU or hospital, moderately severe to severe disability on discharge (modified Rankin scale score = 4–5) and mortality during admission. Compared with those who received swallow screening within 4 h of admission, a delay between 4 and 72 h was associated with greater risks of pneumonia: OR = 1.4 (95%CI:1.1–1.9, P= 0.022), moderately severe to severe disability on discharge: OR = 1.4 (1.1–1.7, P= 0.007) and a delay beyond 72 h was associated with even greater risks of pneumonia: OR = 2.3 (1.4–3.6, P< 0.001), prolonged LOS in HASU: OR = 1.7 (1.0–3.0, P= 0.047, median LOS = 6.2 vs. 14.7 days) and hospital: OR = 2.1-fold (1.3–3.4, P= 0.007, median LOS = 6.8 vs. 14.9 days), moderately severe to severe disability on discharge: OR = 2.5 (1.7–3.7, P< 0.001) and mortality: OR = 3.8 (2.5–5.6, P< 0.001). These risks persisted after excluding 103 patients who died within 72 h. Delay in early screening for swallow capacity in acute stroke patients is detrimental to outcomes, possibly due to delaying nutritional provision or through inappropriate feeding leading to aspiration. Routine early screening needs greater attention in HASUs.
- Published
- 2018
- Full Text
- View/download PDF
5. Atrial fibrillation - the growing epidemic
- Author
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Lip, Gregory Y.H., Kakar, Puneet, and Watson, Timothy
- Subjects
Atrial fibrillation -- Forecasts and trends ,Epidemics -- Reports ,Market trend/market analysis ,Health - Published
- 2007
6. Cerebral Microbleeds and Recurrent Stroke Risk
- Author
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Charidimou, Andreas, Kakar, Puneet, Fox, Zoe, and Werring, David J.
- Abstract
To evaluate cerebral microbleeds (CMBs) and future stroke risk (including intracerebral hemorrhage ICH) in patients with ischemic stroke (IS) or transient ischemic attack.
- Published
- 2013
- Full Text
- View/download PDF
7. Anticoagulation therapy.
- Author
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Kakar, Puneet and Lip, Gregory Y. H.
- Abstract
The article presents information on the use of anticoagulation therapy in the treatment of acute coronary syndromes and acute cerebral ischaemic syndromes. Anticoagulants like warfarin and heparin are used in the therapy to prevent blood coagulation. Therapeutic anticoagulation avoids over-anticoagulation and bleeding risks associated with rapid loading.
- Published
- 2006
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