1. Short-term changes in added sugar consumption by adolescents reflected in the carbon isotope ratio of fingerstick blood
- Author
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Liu, Sarah V, Moore, Lori B, Halliday, Tanya M, Jahren, A Hope, Savla, Jyoti, Hedrick, Valisa E, Marinik, Elaina L, and Davy, Brenda M
- Abstract
Background: Consumption of added sugars (AS) and sugar-sweetened beverages (SSB) may adversely affect adolescents’ weight and cardiovascular disease risk. Reliance on self-reported dietary assessment methods is a common research limitation, which could be overcome by dietary intake biomarkers.Aim: The investigation was a proof-of-concept study to evaluate the proposed carbon isotope ratio (δ13C) biomarker of AS intake in adolescents, using a controlled feeding design.Methods: Participants (n= 33, age 15.3 years, 53% female) underwent two seven-day controlled feeding periods in a randomly assigned order. Diets were matched in composition except for AS content (5% or 25% of total energy). Fasting fingerstick blood samples were collected daily during each diet period.Results: Fingerstick δ13C values changed from day 1 to 8 by –0.05 ± 0.071‰ on 5% AS, and +0.03 ± 0.083‰ on 25% AS (p≤ 0.001). Reliability was demonstrated between day 7 and 8 δ13C values on the 5% (ICC = 0.996, p≤ 0.001) and 25% (ICC = 0.997, p≤ 0.001) AS diets.Conclusions: Larger scale investigations are warranted to determine if this technique could be applied to population-level research in order to help assess the effectiveness of interventions aimed at reducing the consumption of AS or SSB intake.
- Published
- 2018
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