61 results on '"Guillamon, A."'
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2. Social media use for public policymaking cycle: a meta-analysis
- Author
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Nurmandi, Achmad, Wahyuni, Herpita, Guillamon, Maria Dolores, Salahudin, and Muallidin, Isnaini
- Abstract
This study aims to determine the role of social media in policymaking by reviewing journals from 2010 to 2020. This study is a meta-model for the role of social media in policymaking. The method combines the method with data from various data sources, including published documents. Vosviewer and Words were used to examine patterns of relationships or clusters in analysed journals. The data obtained from Scopus helps discuss findings and draw conclusions. The results of the study indicate that social media has a significant influence on public policymaking and governance through: 1) data acquisition and pre-processing; 2) the opinion tracking component addresses hot topics as well as the selection and tracking of sensitive issues; 3) the distributed processing component performs fast processing of data access; 4) public opinion analysis component; 5) public opinion measurement component. This study only compares the results of an analysis of scientific developments in social media and government policies. Future research should examine approaches to making reliable policies and promoting transparency through social media. This study encourages the use of social media as an alternative approach in the policy cycle.
- Published
- 2023
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3. Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries
- Author
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Glasbey, James C, Abbott, Tom EF, Ademuyiwa, Adesoji, Adisa, Adewale, AlAmeer, Ehab, Alshryda, Sattar, Arnaud, Alexis P, Bankhead-Kendall, Brittany, Abou Chaar, M K, Chaudhry, Daoud, Costas-Chavarri, Ainhoa, Cunha, Miguel F, Davies, Justine I, Desai, Anant, Elhadi, Muhammed, Fiore, Marco, Fitzgerald, James Edward, Fourtounas, Maria, Fowler, Alex James, Futaba, Kay, Gallo, Gaetano, Ghosh, Dhruva, Gujjuri, Rohan R, Hamilton, Rebecca, Haque, Parvez, Harrison, Ewen M, Hutchinson, Peter, Hyman, Gabriella, Isik, Arda, Jayarajah, Umesh, Kaafarani, Haytham MA, Kadir, Bryar, Lawani, Ismail, Lederhuber, Hans, Li, Elizabeth, Löffler, Markus W, Lorena, Maria Aguilera, Mann, Harvinder, Martin, Janet, Mazingi, Dennis, McClain, Craig D, McLean, Kenneth A, Meara, John G, Ramos-De La Medina, Antonio, Mengesha, Mengistu, Minaya, Ana, Modolo, Maria Marta, Moore, Rachel, Morton, Dion, Nepogodiev, Dmitri, Ntirenganya, Faustin, Pata, Francesco, Pearse, Rupert, Picciochi, Maria, Pinkney, Thomas, Pockney, Peter, van Ramshorst, Gabrielle H, Richards, Toby, Roslani, April Camilla, Satoi, Sohei, Sayyed, Raza, Shaw, Richard, Simões, Joana FF, Smart, Neil, Sullivan, Richard, Sund, Malin, Sundar, Sudha, Tabiri, Stephen, Taylor, Elliott H, Venn, Mary L, Wickramasinghe, Dakshitha, Wright, Naomi, Yip, Sebastian Bernardo Shu, Bhangu, Aneel, Omar, Omar, Harrison, Ewen, Bhangu, Aneel A, Siaw-Acheampong, Kwabena, Benson, Ruth A, Bywater, Edward, Dawson, Brett E, Evans, Jonathan P, Heritage, Emily, Jones, Conor S, Kamarajah, Sivesh K, Khatri, Chetan, Khaw, Rachel A, Keatley, James M, Knight, Andrew, Lawday, Samuel, Mann, Harvinder S, Marson, Ella J, Mckay, Siobhan C, Mills, Emily C, Pellino, Gianluca, Tiwari, Abhinav, Trout, Isobel M, Wilkin, Richard JW, Abukhalaf, Sadi, Adamina, Michel, Ademuyiwa, Adesoji O, Agarwal, Arnav, Akkulak, Murat, Alameer, Ehab, Alderson, Derek, Alakaloko, Felix, Albertsmeier, Markus, Alser, Osaid, Alshaar, Muhammad, Augestad, Knut Magne, Ayasra, Faris, Azevedo, José, Bankhead-Kendall, Brittany K, Barlow, Emma, Beard, David, Blanco-Colino, Ruth, Brar, Amanpreet, Minaya-Bravo, Ana, Breen, Kerry A, Bretherton, Chris, Buarque, Igor Lima, Burke, Joshua, Caruana, Edward J, Chaar, Mohammad, Chakrabortee, Sohini, Christensen, Peter, Cox, Daniel, Cukier, Moises, Davidson, Giana H, Di Saverio, Salomone, Drake, Thomas M, Edwards, John G, Emile, Sameh, Farik, Shebani, Ford, Samuel, Garmanova, Tatiana, Gomes, Gustavo Mendonça Ataíde, Grecinos, Gustavo, Griffiths, Ewen A, Gruendl, Magdalena, Halkias, Constantine, Hisham, Intisar, Hutchinson, Peter J, Hwang, Shelley, Jenkinson, Michael D, Jonker, Pascal, Keller, Debby, Kolias, Angelos, Kruijff, Schelto, Leventoglu, Sezai, Litvin, Andrey, Loehrer, Andrew, Modolo, Maria Marta, Major, Piotr, Mashbari, Hassan N, Metallidis, Symeon, Mohan, Helen M, Moszkowicz, David, Moug, Susan, Ng-Kamstra, Joshua S, Maimbo, Mayaba, Negoi, Ionut, Niquen, Milagros, Olivos, Maricarmen, Oussama, Kacimi, Outani, Oumaima, Parreno-Sacdalanm, Marie Dione, Rivera, Carlos Jose Perez, Pinkney, Thomas D, Plas, Willemijn van der, Qureshi, Ahmad, Radenkovic, Dejan, Ramos-De La Medina, Antonio, Revell, Elliot J, Roberts, Keith, Roslani, April C, Rutegård, Martin, Segura-Sampedro, Juan José, Santos, Irène, Schache, Andrew, Schnitzbauer, Andreas A, Seyi-Olajide, Justina O, Sharma, Neil, Shaw, Catherine A, Shu, Sebastian, Soreide, Kjetil, Spinelli, Antonino, Stewart, Grant D, Townend, Philip, Tsoulfas, Georgios, Vidya, Raghavan, Vimalachandran, Dale, Warren, Oliver J, Wedderburn, Duane, EuroSurg, NA, European Society of Coloproctology (ESCP), NA, Global Initiative for Children's Surgery, NA, GlobalSurg, NA, GlobalPaedSurg, NA, ItSURG, NA, PTSurg, NA, SpainSurg, NA, Italian Society of Colorectal Surgery, NA, Association of Surgeons in Training, NA, Irish Surgical Research Collaborative (ISRC), NA, Transatlantic Australasian Retroperitoneal Sarcoma Working, NA, Italian Society of Surgical Oncology, NA, Booth, Lesley, Barker, Margaret, Barker, Neil, Cooke, Shirley, Doré, Suzanne, Horwood, Nigel, Runigamugabo, Emmy, Weir, Carrie Tierney, Bahrami-Hessari, Mike, Riaz, Asad, Shah, Jaffer, Safi, Mohammed, Thereska, Dariel, Dajti, Irida, Cheddadi, Riadh, Tidjane, Anisse, Quinteros, Carlos A, khelfaoui, Ahmed, Salem, Khalifa M, Riffi, Omar, Kacimi, Salah Eddine O, Loudjedi, Salim, Damerdji, Tidjani, Pantoja Pachajoa, Diana A, Palacios Huatuco, René M, Alvarez, Fernando A, Doniquian, Alejandro M, Abeldaño Zuñiga, Roberto A, Schlottmann, Francisco, Cobos, Carlos M, Gigena, Cecilia, Forneris, Agustin Albani, Duro, Agustin, García-Mansilla, Agustín M, Busnelli, Virginia Cano, Poggi, Catalina, Mercado, Pedro L, González, Marcos, Castro Lalin, Agustina F, Mayer, Horacio F, Brandariz, Rodrigo, Slullitel, Pablo A, Boudou, Rocio, Lobos, Pablo A, Uffelmann, María C, Petersen, Maria L, Luzzi, Emilia, Padilla Lichtenberger, Fernando L, Crespi Amor, María S, Zarratea, Celeste S, Esteves, Tomas A, Gemelli, Nicolas A, Tirapegui, Sebastián, Liyo, Juan, Scherñuk, Jordán, Boccalatte, Luis A, Balmaceda, Ruben D, D'Addino, Jose L, Caubet, María M, Calderón Arancibia, José A, Chwat, Carina, Morris, Brian, Avellaneda, Nicolas, Pedraza Salazar, Ivana I, Eskinazi, Diego G, Vargas, Lara, Muriel, María E, Lucchini, Sergio M, Gosselink, Martijn P, Davis, Amelia L, Barker, John C, Qin, Kirby R, Proud, David M, Cox, Daniel RA, Goh, Su Kah, Liu, David S, Wu, Damien M, Merrett, Neil D, Badiani, Sarit S, Sengupta, Shomik, Jain, Anshini, Steen, Christopher J, Wong, Enoch, Ip, Christopher CK, Leaning, Matthew G, McCartney, Conor B, Gananadha, Sivakumar, Yeap, Evie FW, Stevens, Sean G, Vu, Anh N, Martin, Sarah A, Stanley, Guy H M, Watson, David I, Townend, Philip J, Young, Thomas K, Cox, Georgia T, Dawson, Amanda C, Laura, Sharon E, Lun, Elizabeth W Y, Liang, Ina X, O'Neill, Christine J, Lott, Natalie J, Chuan, Alwin, Saravanan, SK, Gundara, Justin, Ong, Bee Shan, Nataraja, Ramesh M, Pacilli, Maurizio, Foley, Daniel M, Ooi, Geraldine J, Traeger, Luke, MacDermid, Ewan, Daruwalla, Jurstine, Hodgson, Russell, Heriot, Alexander G, Mulligan, Christopher S, Blefari, Nicholas D A, Purcell, Shaun S, Frankel, Adam J, Guerra, Glen R, Tefay, Joan S, Liang, Rhea W Y, Kroon, Hidde M, Farfus, Anthony W, Warren, Leigh R, Roy, Jennifer M, Whitfield, Robert J, Moller, Cea-Cea B, Davis, Sean S, Sammour, Tarik, Lam, Yick Ho, Kour, Kevin, Gan, Siang Wei, Coventry, Brendon J, Dawson, Joseph A, Batstone, Martin D, King, Sebastian K, Scott, Nathan J, Foo, Jonathan W, Shepherd, Talia, Page, Richard S, Choong, Peter F, Badgery, Henry E, Chong, Lynn, Taylor, Lillian, Hii, Michael W, Wright, Gavin M, Kong, Joseph CH, Watson, Matthew M, Bock, Jacob, Lidder, Surjit S, Elias, Patrick, Kanavathy, Sathisvaran, Koh, Cherry E, Chennakesavan, Srinivas Kondalsamy, Panuganti, Vishwakar, Latif, Haider, Yeung, Justin MC, Besson, Alex J, Tse, Eunice Q Y, Pitcher, Meron E, Taylor, Danielle L, Nahm, Christopher B, Lim, Alicia, Tree, Kevin, Aigner, Felix, Dawoud, Christopher, Foessleitner, Philipp, Zimmermann, Matthias, Wiedemann, Dominik, Findl, Oliver, Messner, Franka, Bauer, Marlies, Nägele, Felix, Kronberger, Irmgard E, Öfner, Dietmar, Härter, Bettina, Bicz, Nina Ru B, Zwittag, Paul M, Poier, Nikolaus, Navarro, Francisco Ruiz, Zebuhr, Yorck A, Köglberger, Paul, Wiesinger, Clemens G, Mathew, Erwin, Trivik-Barrientos, Felipe, Königsrainer, Ingmar, Djedovic, Gabriel, Cohnert, Tina U, Lumenta, David B, Singer, Georg, Leithner, Andreas, Kamolz, Lars-Peter, Andrianakis, Alexandros, Puchwein, Paul, Mikalauskas, Saulius, Kirchweger, Patrick, Függer, Reinhold, Mittermair, Christof, Russe, Elisabeth, Paal, Peter, Grünbart, Martin, de Cillia, Michael, Weiss, Helmut G, Steiner, Florian, Binder, Alf Dorian, Samadov, Elgun, Ibrahimli, Arturan, Muslumov, Gurbankhan, Bayramov, Nuru Y, Saunders, Jada M, Almoosa, Noora, Haj-Ibrahim, Huzifa, Maresch, Martin, Ezzdean, Weaam K, Juma, Isam M, Hasan, Layla H, Haider, Fayza HA, Alfaqawi, Ghassan Salman, Alam, Mohammed S, Islam, Shahnoor, Basher, AKM K, Mitul, Ashrarur Rahman, Islam, Nazmul, Oosterkamp, Antje E, Ahmed, Tanveer, Hannan, M Jafrul, Padmore, Greg M, Doyle, Alex F, LaCorbiniere, Karisha L, Boyce, Rico D R, Ragoobar, Paul T, Walkes, Keisha M Y, Haynes, Amelia A, Corbin, Sasha M, Litvina, Yauheniya A, Makhmudov, Anvar, Strypstein, Sébastien, Dhondt, Bert, Rasschaert, Ricky, Farid, Yasser, Wahib, El Mahdi, Pigeolet, Manon, Belle, Koen Van, De Wachter, Stefan, Komen, Niels, Vandeputte, Mathieu PJ, van Ramshorst, Gabrielle H, Jansen, Yanina JL, Stijns, Jasper, Eynde, Jef Van den, Olowo, Benedicte I, Feraudy, Israel C, Dragisic, Vedran, Martinovic, Vlatka, Barišić, Tatjana, Penava, Nikolina, Hudic, Igor, Delibegovic, Samir, Bogdanović, Gordana, Grgić, Gordana, Cerovac, Anis, Cerovac, Elmedina, Bedada, Alemayehu G, Baiocchi, Glauco, Wainstein, Alberto, Moisés, Elaine Christine D, Zani, Ana Carolina Tagliatti, de Campos Prado, Caio Antonio, Panis, Carolina, Rech, Daniel, Soares da Silva, Ruan Gabriel, Joviliano, Edwaldo E, Rezende, Ricardo F, Reis, Igor G N, Pires, Robinson E S, Christiano, Adriana Borgonovi, Consani, Heitor F X, Pugliesi, Felipe G, Takeda, Flavio R, Mariani, Alessandro W, Valadares, Ricardo J B, Andreollo, Nelson A, Lopes, Luiz Roberto, Tonello, Cristiano, Alonso, Nivaldo, dos Santos, Carlos Ferreira, Lima, Leonardo S, Salgado, Wilson, Pereira, Thiago H S, Gatti, Arthur Paredes, Oliva, Ramon N L, Nardi, Caroline N, Sousa, Alvaro F L, Ribeiro, Ivonizete P, Carvalho, Herica E F, Oliveira, Layze B, Schneider, Guilherme, Casteleins, William Augusto, Silva, Larissa M, Gomes, Carlos Augusto, da Cunha Viana Júnior, Alonço, Cruz, Ricardo P, Gomes, Gustavo MA, Buarque, Igor L, Barros, Aldo V, Marangon, Gustavo B, Flumignan, Ronald LG, Nakano, Luís CU, Pascoal, Patrícia IF, Santos, Brena C, Kuramoto, Danielle AB, Correia, Rebeca M, Amaral, Fabio CF, Flumignan, Carolina DQ, Dussán-Sarria, Jairo A, Simões, Romeo L, Casteleins, William Augusto, Amorim, Robson L, Silva, Jeancarllo S, Lyra Junior, Humberto F, Julio, Nathalia S, Gerber, Marlus T, dos Santos, José Mauro, de Oliveira, Joao Carlos C, Palamim, Camila VC, Marson, Fernando AL, Gomes, Iolanda M, Oliveira, Priscila R, Lima, Ana Lucia L M, Carvalho, Vladimir C, Silva, Jorge S, NA, Ulysses Ribeiro, Laporte, Gustavo Andreazza, Gonçalves, Mateus Capuzzo, Botacin, Lais S, Avelino, Melissa AG, Brito, Luiz Gustavo O, Hristova, Evguenia T, Stoyanov, Vladislav Valentinov, Sakakushev, Boris E, Dardanov, Dragomir D, Sokolov, Manol B, Mehta, Ananya, Gyokova, Elitsa H, Abdullahi, Mohamed, Karamanliev, Martin P, Dimitrov, Dobromir D, Slavchev, Mihail T, Atanasov, Boyko Ch, Yotsov, Tsanko I, Hadzhiev, Dimitar Bozhidarov, Stock, Simon E, Nwegbu, Chukwuemeka Gerald, Tanyi, Tanyi John, Brown, James A, Arneja, Jugpal S, Lee, Susan M, Kancherla, Ramya, Kidane, Biniam, Champagne, Pierre-Olivier, Ma, Xiya, Munro, Allana, McKeen, Dolores M, Martin, Janet, Glinka, Juan, Vasarhelyi, Edward M, Subramani, Yamini, Alfaro, Hilda, Shah, Ushma J, Gonzalez, Nelson J, MacNeil, S Danielle, Nagappa, Mahesh, Malthaner, Richard A, Brackstone, Muriel, Alkhamesi, Nawar A, Qiabi, Mehdi, Arango-Ferreira, Camila, Prempeh, Agya B A, Dumitra, Sinziana, Spence, Richard T, Bedard, Eric LR, Lee, Susan M, Luc, Jessica GY, Johnston, Brian R, Attabib, Najmedden, Persad, Amit RL, Das, Sunit, Khoshbin, Amir, Ladha, Karim S, Sankar, Ashwin, Teja, Bijan, Daza, Julian F, Chan, Veronica F, Baertschiger, Reto M, Zani, Augusto, Nessim, Carolyn, McIsaac, Daniel I, Singh, Mandeep, Behzadi, Abdollah, Dell, Angela J, Al Riyami, Salim M, Dajani, Khaled Z, Bigam, David, Manikala, Vinod K, Street, John T, Mayson, Kelly V, Wallis, Christopher J D, Mimica, Ximena, Modolo, Maria Marta, Villanueva, Julio, Altamirano, Roberto, Waissbluth, Sofia, Marín, Diego I, Olivos, Maricarmen, Fonseca, Bruno Catoia, Hodali, Andrés J, Ramos, Andrea I, Valenzuela, Marco A, Torres, Janina J, Song, Yi, Yang, Wah, Safi, Mohammed, Aldanakh, Abdullah, Alradhi, Mohammed, Lyu, Yidong, Chen, Yan, Fletcher, Angélica V, Camargo, Daniela, Casanova, Rafael Figueroa, Medina, Camilo Andres Caicedo, Bolivar, Dinimo, Garcia, Tatiana Carolina Beltran, Pedraza, Nestor F, Garcia-Lopez, Andrea, Patino-Jaramillo, Nasly G, Giron, Fernando A, Rivera, Carlos J- Perez, Nieto-Calvache, Albaro José, Ariza, Fredy, Orozco-Chamorro, Claudia Milena, Nanez, Maria A, Garces, Diana S, Figueroa, Luis M, Badiel, Marisol, Martinez, Delio F, Coll-Tello, Brenda, Camelo, Hector F, Montoya Casella, Antonio J, Ordoñez, Sebastian, Velez Sanchez, Paola A, Salcedo, Juan C, Villegas, Lina M, Holguín, Jorge A, Cardozo, Jesús Hernán Tovar, Perdomo, Jorman Harvey Tejada, Perdomo, Valentina Gutiérrez, Rivera-Rincon, Natalia A, Gomez, Paula Torres, Delgado-Nieto, Elena Leonor, Isaza-Restrepo, Andres, Vargas, Felipe, Vargas, Ana M, Castro, Arnulfo Andrade, Navarro, Jorge A, Vargas, Saul E, Calvache, Jose A, Mendoza-Arango, Maria C, Bernal, Jorge Luis Vélez, Gonzalez, Felipe O, šantak, Goran, Kirac, Iva, Kršul, Dorian, Versic, Ana Bosak, Augustin, Goran, Kulis, Tomislav, Kastelan, Zeljko, Hadzibegovic, Ana Danic, Grsic, Kresimir, Hudolin, Tvrtko, Tarle, Marko, Mamic, Matija, Lorencin, Mia, Luksic, Ivica, Habek, Dubravko, Konjevoda, Suzana, Mihanovic, Jakov, Antoniou, Stavros A, Almezghwi, Heyam A, Gouvas, Nikolaos, Martinek, Lubomir, Novysedlak, Rene, Žatecký, Jan, Christensen, Peter, Meyhoff, Christian S, Ellebæk, Mark Bremholm, Batista, Sylvia Jeanne, Rodriguez, Julia, Mejia De la Cruz, Dolores, Jimenez, Mirna Giselle Santiago, Dominguez, Carla M, Negrete, José R, Campuzano, Pedro N, Mogrovejo, Daniel L, Armas, Maria J, Arboleda-Bustan, Jenny E, Lincango-Naranjo, Eddy P, El-Kassas, Mohamed, Awad, Ahmed K, Alazab, Emad, Abdulmaseh, Kyrillos G, Diab, Sherein, El Wahab, Mostafa HAbd, Darwesh, Amr, Mostafa, Badr E, Abdelgalil, Mahmoud Shaban, Elbadawy, Merihan A, Reda, Ali M, Asla, Amir Fathi, Fayed, Notaila M, Ahmed, Mohamed S, Elsadek, Menan Ahmed, Gad, Dalia Elsayed, El Saadany, Aya Gameel, Elsadek, Aalaa Mohamed, Asla, Amir Fathi, Sayed, Ahmed E, Naeem, Ahmed, Al-Mallah, Abdullah, Abdelsamed, Ahmed A, Ewedah, Moataz, Soliman, Mohamed O, Tanas, Yousef, Hamouda, Mohammed, Mahfouz, Marina H, Abdo, Manal E, Dean, Yomna E, Lka, Karim, Abodeeb, Aya O, Ashoush, Fouad M F B, Elsherbiny, Roqaia R, Gadelkarim, Mohamed, Osman, Nermin A, MIbrahim, Maya, Youssef, Nehal G, Ibrahim, Mohamed Hamdy, Soliman, Antonios, Gadelkareem, Rabea A, Abbas, Ahmed M, Mohamed Hussein, Aliae AR, Abdelsattar, Khaled, Maher, Ahmed, Elabd, Mohamed M, Abdelazim, Hassan, Ibraheem, Maher H, Noureldin, Yasser A, Elfiky, Mahmoud, Ebrahim, Mohamed A, Abdelrahman, Ahmed Saber Mohamed, Marei, Mahmoud Marei, Elkhalawy, Aya M, Azzam, Ahmed Y, Azab, Mohammed A, Elmasry, Ahmed H, Awad, Ahmed K, Elgazar, Amr, Shalaby, Mahmoud Mohamed Mohamed, Mahmoud, Mohammad S, Qassem, Mohamed G, Kinani, Hussein, Wahba, Abdelrahman M, Elbadawy, Merihan A, Ezzat, Rana Hisham, Ahmed, Mai H, Elshawy, Mohamed Elemam, Faragalla, Hazem Metwally, Mahmoud, Khalid D, Nafea, Ahmed M, Abdel-Maboud, Mohamed, Abozied, Hesham, Moharam, Modather, Shehata, Ashraf H, ElKafrawy, Samir A, Tayiawi, Mosaab M, Elghadban, Hosam M, Emara, Moataz M, Shehta, Ahmed, Saqr, Amira M, Abdelelsalm, Wafaa M, Elshennawy, Eslam M, Radwan, Samar T, Awad, Selmy S, Emile, Sameh H, Aldosoky, Wesam A, Elfeki, Hossam, Gendi, Sara N, Abdelsalam, Hala Adel, Hammad, Mohammed, Shalaby, Mostafa, Sakr, Ahmad Hammad, Abdelmaksoud, Mohamed A, Alawady, Mohammed, Omran, Abdelrahman Azzam, Allam, Abdallah R, Ismail, Zainab, Gaballah, Khaled M, AlGady, Mahmoud Fathy Mahmoud, Raslan, Ahmed M, Gharbia, Khaled, Nuser, Abdelazez A, Sayed, Ahmed Kamal, Al-Mallah, Abdullah, Elshahawy, Mahmoud A, Ghaly, Galal, Sherif, Ahmed Elshawadfy, Makram, Abdelrahman M, Makram, Omar M, Ahmed, Ola, Helmy, AbdelRahman M A, Abdelwahab, Khaled M, Abdelkhalek, Mohamed, Metwally, Islam H, Shetiwy, Mosab Saad, Zuhdy, Mohammad, Ramadan, Salma I, Abdelghany, Mohamed, Omar, Mohammed A, Soliman, Ziad A, Ali, Hossam T, Elnoamany, Salma, Ghozy, Sherief, Abbas, Alzhraa S, Shehata, Mostafa A, Mahmoud, Sahar A, Elsaman, Mohammed A, Fayad, Elsayed A, Radwan, Asmaa, El-Sakka, Ahmed I, Sallam, Asser, Elbahnasawy, Mohamed G, Esmail, Eslam S, Hawila, Ahmed Maher, Hamada, Mohamed K, Motawea, Sara H, Morsy, Mohamed S, El-Sheemy, Hatem Refaat, Ebada, Mahmoud Ahmed, Khedr, Ali H, Gad, Ahmed, Elmandouh, Omar, Elmandouh, Reem, Alkanj, Souad, Youssef, Mohammad G, Awad, Kamal, Mohammed, Maged, Elsayad, Ahmed H, Rätsep, Tõnu, Wolle, Melatework A, Negussie, Abraham G, Adimass, Misganaw A, Misganaw, Bereket Tsegaye, Bezabih, Yoseph S, Assefa, Biniam Zemedu, Shumye, Getachew W, Mengesha, Mengistu G, Gechera, Dagnachew Y, Mohammed, Adnan A, Mulugeta, Gersam A, Metaferia, Yonas Y, Kifetew, Ashebir B, Degefa, Eyueal A, Deressa, Yadani M, Gonfa, Kebebe Bekele, Bedane, Zewdie G, Ayalew, Alem M, Ayele, Henok Teshome, Abebe, Engida, Worku, Bereket Atnafu, Sisay, Million M, Kassa, Dawit Worku, Awedew, Atalel F, Bayable, Abera C, Tiruneh, Abraham Genetu, Hailu, Samuel, Numaro, Yilkal T, Ademe, Yonas, Baleh, Abat S, Megerssa, Thomas B, Kejela, Segni, Derilo, Habtamu T, Akililu, Yemisirach B, Lebbe, Iris, Sarjanoja, Elise K, Kauppila, Joonas H, Sinikumpu, Juha-Jaakko, Giordano, Salvatore, Kantor, Elie, Soussan, Romy, Tommaso, Cipolat Mis, Nappi, Francesco, Morichau-Beauchant, Tristan, Nahum, Julien, Maillet, Jean-Michel, Godement, Mathieu, Jouffret, Lionel, Migliorelli, Federico, De Simone, Belinda, Brunaud, Laurent, Fuchs-Buder, Thomas, Testelin, Sylvie, Bin, Kim, Boucher, Sophie, Schmitt, Françoise, Lakkis, Zaher, Harper, Luke, Slim, K, Piessen, Guilaume, Eveno, Clarisse, Ballouhey, Quentin, Taibi, Abdelkader, Crenn, Vincent, Duchalais, Emilie, Arnaud, Alexis P, Azzis, Olivier, Tuech, Jean-Jacques, Vaysse, Charlotte, Weyl, Ariane, Vergriete, Kelig, Charbonneau, Helene, Ezanno, Anne-Cecile, Malgras, Brice, Basso, Celeste Del, Duquesne, Igor, Bernabei, Federico, Rothschild, Pierre-Raphaël, Abbo, Olivier, Manceau, Gilles, Chamouni, Alexandre, Crétolle, Célia, Arnalsteen, Laurent, Mikhael, Elie, Police, Andrea, Montero-Macias, Rosa, Villefranque, Vincent, Maisonneuve, Emeline, Langlais, Tristan, Seeliger, Barbara, Pessaux, Patrick, Gonzalez, Cristians A, D'Urso, Antonio, Angeles, Martina A, Seguin-Givelet, Agathe, Des Deserts, Marc Danguy, Gaujoux, Sebastien, de Ponthaud, Charles, Chartier-Kastler, Emmanuel J, Ali, Liza, Peycelon, Matthieu, Mege, Diane, Demetrashvili, Zaza, Stoleriu, Mircea G, Keppler, Lena, Saier, Tim, Konrads, Christian, Tapking, Christian, Kamphues, Carsten, Bulian, Dirk R, Schmedding, Andrea, Doerner, Johannes, Gut, Anna E, Rolinger, Jens, Kirschniak, Andreas, Schröder, Lars, Reim, Daniel, Safi, Seyer, Fichter, Andreas M, Wagner, Arthur, Meyer, Bernhard, Gempt, Jens, Sablotzki, Armin R, Herzberg, Jonas, Altenburg, Manuel, Yenilmez, Ferhat, Meins, Jan, Aghwan, Louai A, Börner, Nikolaus, Keppler, Alexander M, Albertsmeier, Markus, Seyfried, Steffen, Rassweiler-Seyfried, Marie-Claire, Kriegmair, Maximilian, Kowalewski, Karl-Friedrich, Gousias, Konstantinos, Strotmann, Johanna J, Höhn, Philipp, Horn, Julian, Knipschild, Julia M, Siemen, Leonie, Luu, Andreas Minh, Horch, Raymund E, McLean, Aaron Lawson, Lindert, Judith Anne Teresa, Ziemann, Sebastian, Modabber, Ali, Winnand, Philipp, Hölzle, Frank, Sommer, Björn, Wolf, Sebastian, Shiban, Ehab, Recker, Florian, Güresir, Erdem, Randau, Thomas M, Güresir, Agi, Velten, Markus, Vilz, Tim O, Wittmann, Maria, Willis, Maria A, Glowka, Tim R, Bork, Ulrich, Hecker, Matthias, Hecker, Andreas, Reichert, Martin, Miller, Clemens, Nemeth, Marcus, Ronellenfitsch, Ulrich, Kleeff, Jorg, Lorenz, Kerstin, Kisser, Ulrich, Schneider, Rick, Seiwerth, Ingmar, Osterhoff, Georg, Linz, Valerie C, Mallmann, Michael R, Rokohl, Alexander C, Heindl, Ludwig M, Wawer Matos, Philomena A, Cursiefen, Claus, Mallmann, Christoph A, Domroese, 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Muhammed Kadir, Atici, Semra Demirli, Salimoğlu, Semra, Abud, Burcin, Calik, Bulent, Kamer, Erdinc, Kebabci, Eyup, Uylas, Ufuk, Teker, Kenan, Cakmak, Guldeniz Karadeniz, Gultekin, Fatma Ayca, Xaviour, Okedi Francis, Isaac, Otolia, Gaston, Turinawe, Asiimwe, Daniel, Vahwere, Bienfait Mumbere, Sikakulya, Franck Katembo, Lule, Herman, Lugobe, Henry Mark, Lekuya, Hervé Monka, Namugenyi, Christine, Kiweewa, Ronald, Bosco, Muhangi, Yovenko, Ihor, Kopetskyi, Viacheslav, Maksymenko, Bogdan, Alshryda, Sattar, Khan, Sabina A, Padvi, Amit Vasantrao, Serour, Mohamed A, Beigh, Shamim Ahmad, Elsayed, Hisham M, Mohamed, Awadelkarim O, Basappanavar, Vikram Somashekhar, Al-Wandi, Amna S, Khalil, Kareem S, Younis, Muhammad Umar, Al Saadi, Hayder S Abdulhadi, Heidan, Ginan K, Trehan, Ravi K, Davies, Justin, Ashcroft, James, Stewart, Grant D, Georgiades, Fanourios, Durrani, Amer J, Price, Stephen J, Wong, Kai Yuen, Agrawal, Amit, Seah, Matthew KT, Saad, Marwa M E, Segaren, Nicholas, Ghobrial, Marios, 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Gabriela, Malam, Yogeshkumar, Townson, Adam, Loubani, Mahmoud, Yau, Jih Dar, Seebah, Kevin, Akowuah, Enoch F, Pushpoth, Sreekumari R, Viswanath, Yirupaiahgari KS, ElSanhoury, Kareem, Chew, Misha, Walker, Thomas E, Elhassan, Almutasim Billah Elbagir, Belcher, Elizabeth, Goricar, Matej, majd, Hooman Soleymani, Knight, Dominic, Ismail, Lamiese, McKinnon, Chris, Ganau, Mario, Prokopenko, Max, Doshi, Neel S, Gkorila, Aikaterina, Sheikh, Nomaan A, Helm, Jessica R, Low, Mei Ken, Ogunfusika, Oluseyi Harold, Bisheet, George, Alhammali, Tariq, Arnob, Ahmed Showki, Singh, Jatinder, Allde, Emma L, Sambhwani, Sharan H, Dube, Manas, Gemmill, Elizabeth H, John, Joby, Gerogiannis, Ioannis N, Abuelgasim, Mona A A, Crate, Georgina, Holme, Thomas J, Nguyen, Anh T V, Ho, Michael W, Wade, Ryckie G, Hussain, Azar, Andrzejowski, Paul, Omakobia, Eugene, Eltayeb, Momin, Galabov, Tsanko P, Lee, Chung Yan Vernon, Nazir, Anum, Siaw, Oliver L, Ashford, Robert U, Boddy, Alex P, Ashmore, Christopher D, Shah, Snehadhar M, Gowers, Benjamin T V, Thekkinkattil, Dinesh K, Worku, Dawit, Sambhwani, Sharan H, Harky, Amer, Talwar, Rishi, Sagoo, Harkiran K, Jambulingam, Periyathambi S, Smart, Christopher J, Doherty, Daniel T, Mastoridis, Sotiris, Kumar, Sidharth, Mahmoud, Rana, Solari, Francesca, Egan, Richard J, Barry, Jonathan D, Morrison, Jo, Davoudi, Kaveh, Hollyman, Marianne, Kelly, Andrew, Badenoch, Thomas F, pandanaboyana, sanjay, Critchley, Rebecca J, Sarodaya, Varun R, Sinnerton, Robert J H, Manickavasagam, Jaiganesh, Lindsay, Elizabeth F, Arora, Ankita, Hasan, Raashad, Liew, Ignatius, Ozua, Joshua, Kouritas, Vasileios, Collins, Rachael V, Lafford, George H, Moret, Charlie, Chean, Chung Shen, Horgan, Liam F, Aujayeb, Avinash, Siddique, Muhammad Harris, Navaratne, Lalin, Kotecha, Sanjeev, Bellato, Vittoria, Lewis, Sophia E, Ali, Muhammad Usman, Marson, Ben A, Craxford, Simon, Gajjar, Ketankumar, Theophilidou, Elena, Aboelmagd, Tariq, Khatkar, Harman, Ganau, Mario, Awadallah, Mahmoud A, 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Abdullah, Goru, Poornanand, Baumber, Rachel M, Sobti, Anshul S, Cross, George WV, Havenhand, Tom, Antoniou, George A, Chauhan, Govind Singh, Vokshi, Ismail, Mahmud, Ayesha, Albanese, Erminia, Evans, Daisy, Madhuri, Thumuluru Kavitha, Horsnell, Jonathan D, Zalmay, Pardis, Mohamed, Mazin, Davies, Angharad J, Aljanadi, Firas, Jeganathan, Reubendra, Jones, Mark, Kakos, Christos, vidya, Raghavan, El-Ghobashy, Alaa, Habib, Ahmed M, Reid, Jeremy P, Rajgor, Harshadkumar Dhirajlal, Ahmed, Omar, Branagan, Graham, Mohamedahmed, Ali Yasen Y, Nour, Shahd, Al-Sabbagh, Ali, Chetty, Govind, Kelty, Clive J, EL-Wajeh, Yasin A M, Tomlinson, James E, Edwards, John G, Rominiyi, Ola, Sinha, Saurabh, Saad, Sanad, Sahu, Banchhita, Charalampakis, Vasileios, Enemosah, Ibrahim, Williams, Simon J, Yaqoob, Hassan N, Laurent, Edward P, Moreau, Joshua L, Frostick, Rhiannon, Parwaiz, Hammad, Aboelmagd, Karim, Pournaras, Dimitri J, Hristova, Kalina H, Iyengar, Karthikeyan P, Mohamed, Muyed, Artioukh, Dmitri Y, Anwar, 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Siamuchembu, Maphios, Bondera, Tafadzwa, and Mushawarima, Trust
- Abstract
The 2015 LancetCommission on global surgery identified surgery and anaesthesia as indispensable parts of holistic health-care systems. However, COVID-19 exposed the fragility of planned surgical services around the world, which have also been neglected in pandemic recovery planning. This study aimed to develop and validate a novel index to support local elective surgical system strengthening and address growing backlogs.
- Published
- 2022
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4. Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities
- Author
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Ikezu, Seiko, Yeh, Hana, Delpech, Jean-Christophe, Woodbury, Maya E., Van Enoo, Alicia A., Ruan, Zhi, Sivakumaran, Sudhir, You, Yang, Holland, Carl, Guillamon-Vivancos, Teresa, Yoshii-Kitahara, Asuka, Botros, Mina B., Madore, Charlotte, Chao, Pin-Hao, Desani, Ankita, Manimaran, Solaiappan, Kalavai, Srinidhi Venkatesan, Johnson, W. Evan, Butovsky, Oleg, Medalla, Maria, Luebke, Jennifer I., and Ikezu, Tsuneya
- Abstract
Maternal immune activation (MIA) disrupts the central innate immune system during a critical neurodevelopmental period. Microglia are primary innate immune cells in the brain although their direct influence on the MIA phenotype is largely unknown. Here we show that MIA alters microglial gene expression with upregulation of cellular protrusion/neuritogenic pathways, concurrently causing repetitive behavior, social deficits, and synaptic dysfunction to layer V intrinsically bursting pyramidal neurons in the prefrontal cortex of mice. MIA increases plastic dendritic spines of the intrinsically bursting neurons and their interaction with hyper-ramified microglia. Treating MIA offspring by colony stimulating factor 1 receptor inhibitors induces depletion and repopulation of microglia, and corrects protein expression of the newly identified MIA-associated neuritogenic molecules in microglia, which coalesces with correction of MIA-associated synaptic, neurophysiological, and behavioral abnormalities. Our study demonstrates that maternal immune insults perturb microglial phenotypes and influence neuronal functions throughout adulthood, and reveals a potent effect of colony stimulating factor 1 receptor inhibitors on the correction of MIA-associated microglial, synaptic, and neurobehavioral dysfunctions.
- Published
- 2021
- Full Text
- View/download PDF
5. Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data
- Author
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Thomalla, Götz, Boutitie, Florent, Ma, Henry, Koga, Masatoshi, Ringleb, Peter, Schwamm, Lee H, Wu, Ona, Bendszus, Martin, Bladin, Christopher F, Campbell, Bruce C V, Cheng, Bastian, Churilov, Leonid, Ebinger, Martin, Endres, Matthias, Fiebach, Jochen B, Fukuda-Doi, Mayumi, Inoue, Manabu, Kleinig, Timothy J, Latour, Lawrence L, Lemmens, Robin, Levi, Christopher R, Leys, Didier, Miwa, Kaori, Molina, Carlos A, Muir, Keith W, Nighoghossian, Norbert, Parsons, Mark W, Pedraza, Salvador, Schellinger, Peter D, Schwab, Stefan, Simonsen, Claus Z, Song, Shlee S, Thijs, Vincent, Toni, Danilo, Hsu, Chung Y, Wahlgren, Nils, Yamamoto, Haruko, Yassi, Nawaf, Yoshimura, Sohei, Warach, Steven, Hacke, Werner, Toyoda, Kazunori, Donnan, Geoffrey A, Davis, Stephen M, Gerloff, Christian, Acosta, Boris Raul, Aegidius, Karen, Albiker, Christian, Alegiani, Anna, Almendrote, Miriam, Alonso, Angelika, Althaus, Katharina, Amarenco, Pierre, Amiri, Hemasse, Anders, Bettina, Aniculaesei, Adriana, Appleton, Jason, Arenillas, Juan, Back, Christina, Bähr, Christian, Bardutzky, Jürgen, Baronnet-Chauvet, Flore, Bathe-Peters, Rouven, Bayer-Karpinska, Anna, Becerra, Juan L., Beck, Christoph, Belchí Guillamon, Olga, Benoit, Amandine, Berhoune, Nadia, Bindila, Daniela, Birchenall, Julia, Blanc-Lasserre, Karine, Blanco Gonzales, Miguel, Bobinger, Tobias, Bodechtel, Ulf, Bodiguel, Eric, Bojaryn, Urszula, Bonnet, Louise, Bouamra, Benjamin, Bourgeois, Paul, Boutitie, Florent, Breuer, Lorenz, Breynaert, Ludovic, Broughton, David, Brouns, Raf, Brugirard, Sébastian, Bruneel, Bart, Buggle, Florian, Cakmak, Serkan, Calleja, Ana, Calvet, David, Carrera, David, Chen, Hsin-Chieh, Cheng, Bastian, Cheripelli, Bharath, Cho, Tae-Hee, Choe, Chi-un, Choy, Lillian, Christensen, Hanne, Ciatipis, Mareva, Cloud, Geoffrey, Cogez, Julien, Cortijo, Elisa, Crozier, Sophie, Damgaard, Dorte, Dani, Krishna, De Coene, Beatrijs, De Hollander, Isabel, De Keyser, Jacques, De Klippel, Nina, De Maeseneire, Charlotte, De Smedt, Ann, del Mar Castellanos Rodrigo, Maria, Deltour, Sandrine, Demeestere, Jelle, Derex, Laurent, Desfontaines, Philippe, Dittrich, Ralf, Dixit, Anand, Dobbels, Laurens, Domigo, Valérie, Dorado, Laura, Druart, Charlotte, Dupont, Kristina Hougaard, Dusart, Anne, Dziewas, Rainer, Ebinger, Martin, Ebner, Matthias, Edjali-Goujon, Myriam, Eisele, Philipp, El Tawil, Salwa, Elhfnawy, Ahmed, Endres, Matthias, Etexberria, Ana, Evans, Nicholas, Fandler, Simon, Fazekas, Franz, Felix, Sandra, Fiebach, Jochen B., Fiehler, Jens, Filipov, Alexandra, Filipski, Katharina, Fleischmann, Robert, Foerch, Christian, Ford, Ian, Gaenslen, Alexandra, Galinovic, Ivana, Gancedo, Elena Meseguer, Ganeshan, Ramanan, García Esperón, Carlos, Garrido, Alicia, Gattringer, Thomas, Geraghty, Olivia, Geran, Rohat, Gerloff, Christian, Gerner, Stefan, Godon-Hardy, Sylvie, Göhler, Jos, Golsari, Amir, Gomis, Meritxell, Gorriz, David, Gramse, Verena, Grau, Laia, Griebe, Martin, Guerrero, Cristina, Guerzoglu, Damla, Guettier, Sophie, Guiraud, Vincent, Gumbinger, Christoph, Gunreben, Ignaz, Haertig, Florian, Hametner, Christian, Hanseeuw, Bernard, Hansen, Andreas, Hansen, Jakob, Harbo, Thomas, Harloff, Andreas, Harmel, Peter, Häusler, Karl Georg, Heinen, Florian, Held, Valentin, Hellwig, Simon, Hemelsoet, Dimitri, Hennerici, Michael, Herm, Juliane, Hermans, Sylvia, Hernández, María, Hervas Vicente, Jose, Hjort, Niels, Hobeanu, Cristina, Hobohm, Carsten, Höfner, Elmar, Hohenbichler, Katharina, Hommel, Marc, Hoppe, Julia, Hornberger, Eva, Hoyer, Carolin, Huang, Xuya, Ipsen, Nils, Isern, Irina, Ispierto, Lourdes, Iversen, Helle, Jeppesen, Lise, Jimenez, Marta, Jungehülsing, Jan, Jüttler, Eric, Kalladka, Dheeraj, Kallmünzer, Bernd, Kar, Arindam, Kellert, Lars, Kemmling, André, Kessler, Tobias, Khan, Usman, Klein, Matthias, Kleinschnitz, Christoph, Klockziem, Matti, Knops, Michael, Koehler, Luzie, Koehrmann, Martin, Kohlfürst, Heinz, Kollmar, Rainer, Kraft, Peter, Krause, Thomas, Kristensen, Bo, Kröber, Jan M., Kurka, Natalia, Ladoux, Alexandre, Laloux, Patrice, Lamy, Catherine, Landrault, Emmanuelle, Lauer, Arne, Lebely, Claire, Leempoel, Jonathan, Lees, Kennedy, Leger, Anne, Legrand, Laurence, Lemmens, Robin, Li, Lin, Löbbe, Anna-Mareike, London, Frederic, Lopez-cancio, Elena, Lorenz, Matthias, Louw, Stephen, Lovelock, Caroline, Lozano Sánchez, Manuel, Lucente, Giuseppe, Lückl, Janos, Luna, Alain, Macha, Kosmas, Machet, Alexandre, Mackenrodt, Daniel, Madzar, Dominik, Majoie, Charles, Männer, Anika, Maqueda, Vicky, Marstrand, Jacob, Martinez, Alicia, Marzina, Annika, Mechthouff, Laura, Meden, Per, Meersman, Guy, Meier, Julia, Mellerio, Charles, Menn, Oliver, Meyer, Nadja, Michalski, Dominik, Michels, Peter, Michelsen, Lene, Millán Torne, Monica, Minnerup, Jens, Modrau, Boris, Moeller, Sebastian, Møller, Anette, Morel, Nathalie, Moreton, Fiona, Morin, Ludovic, Moulin, Thierry, Moynihan, Barry, Mueller, Anne K., Muir, Keith W., Mulero, Patricia, Mundiyanapurath, Sibu, Mutzenbach, Johannes, Nagel, Simon, Naggara, Oliver, Nallasivan, Arumugam, Navalpotro, Irene, Nave, Alexander H., Nederkoorn, Paul, Neeb, Lars, Neugebauer, Hermann, Neumann-Haefelin, Tobias, Nighoghossian, Norbert, Oberndorfer, Stefan, Opherk, Christian, Oppel, Lorenz, Oppenheim, Catherine, Orthgieß, Johannes, Ostergaard, Leif, Paindeville, Perrine, Palomeras, Ernest, Panitz, Verena, Patel, Bhavni, Peeters, Andre, Peeters, Dirk, Pellisé, Anna, Pelz, Johann, Pereira, Anthony, Pérez de la Ossa, Natalia, Perry, Richard, Petraza, Salvador, Peysson, Stéphane, Pfeilschifter, Waltraud, Pichler, Alexander, Pierskalla, Alexandra, Pledl, Hans-Werner, Poli, Sven, Pomrehn, Katrin, Poulsen, Marika, Prats, Luis, Presas, Silvia, Prohaska, Elisabeth, Puetz, Volker, Puig, Josep, Puig Alcántara, Josep, Purrucker, Jan, Quenardelle, Veronique, Ramachandran, Sankaranarayanan, Raphaelle, Soulliard, Raposo, Nicolas, Reiff, Tilman, Remmers, Michel, Renou, Pauline, Ribitsch, Martin, Richter, Hardy, Ringleb, Peter, Ritter, Martin, Ritzenthaler, Thomas, Rodier, Gilles, Rodriguez-Regent, Christine, Rodríguez-Yáñez, Manuel, Roennefarth, Maria, Roffe, Christine, Rosenbaum, Sverre, Rosso, Charlotte, Röther, Joachim, Rozanski, Michal, Ruiz de Morales, Noelia, Russo, Francesca, Rutgers, Matthieu, Sagnier, Sharmilla, Samson, Yves, Sánchez, Josep, Sauer, Tamara, Schäfer, Jan H., Schieber, Simon, Schill, Josef, Schlak, Dennis, Schlemm, Ludwig, Schmidt, Sein, Schonewille, Wouter, Schröder, Julian, Schulz, Andreas, Schurig, Johannes, Schwarting, Sönke, Schwarz, Alexander, Schwarzbach, Christopher, Seidel, Matthias, Seiler, Alexander, Sembill, Jochen, Serena Leal, Joaquin, Shetty, Ashit, Sibon, Igor, Simonsen, Claus Z., Singer, Oliver, Sivagnanaratham, Aravinth, Smets, Ide, Smith, Craig, Soors, Peter, Sprigg, Nikola, Spruegel, Maximilian, Stark, David, Steinert, Susanne, Stösser, Sebastian, Stuermlinger, Markus, Swinnen, Bart, Tamazyan, Ruben, Tembl, Jose, Terceno Izaga, Mikel, Thijs, Vincent, Thomalla, Götz, Touze, Emmanuel, Truelsen, Thomas, Turc, Guillaume, Turine, Gaetane, Tütüncü, Serdar, Tyrell, Pippa, Ustrell, Xavier, Vadot, Wilfried, Vallet, Anne-Evelyne, Vallet, Pauline, van den Berg, Lucie, van den Berg, Sophie, van Eendenburg, Cecile, Van Hooff, Robbert-Jan, van Sloten, Isabelle, Vanacker, Peter, Vancaester, Evelien, Vanderdonckt, Patrick, Vandermeeren, Yves, Vanhee, Frederik, Veltkamp, Roland, Vestergaard, Karsten, Viguier, Alain, Vilas, Dolores, Villringer, Kersten, Voget, Dieke, von Schrader, Jörg, von Weitzel, Paul, Warburton, Elisabeth, Weber, Claudia, Weber, Jörg, Wegscheider, Karl, Wegscheider, Mirko, Weimar, Christian, Weinstich, Karin, Weise, Christopher, Weise, Gesa, Willems, Chris, Winder, Klemens, Wittayer, Matthias, Wolf, Marc, Wolf, Martin, Wolff, Valerie, Wollboldt, Christian, Wollenweber, Frank, Wouters, Anke, Yalo, Bertrand, Yger, Marion, Younan, Nadia, Yperzeele, Laetita, Zegarac, Vesna, Zeiner, Pia, Ziemann, Ulf, Zonneveld, Thomas, Zuber, Mathieu, Akutsu, Tsugio, Aoki, Junya, Aoki, Junya, Arakawa, Shuji, Doijiri, Ryosuke, Egashira, Yusuke, Enomoto, Yukiko, Fukuda-Doi, Mayumi, Furui, Eisuke, Furuta, Konosuke, Gotoh, Seiji, Hamasaki, Toshimitsu, Hasegawa, Yasuhiro, Hirano, Teryuki, Homma, Kazunari, Ichijyo, Masahiko, Ide, Toshihiro, Igarashi, Shuichi, Iguchi, Yasuyuki, Ihara, Masafumi, Ikenouchi, Hajime, Inoue, Manabu, Inoue, Tsuyoshi, Itabashi, Ryo, Ito, Yasuhiro, Iwama, Toru, Kamiyama, Kenji, Kamiyoshi, Shoko, Kanai, Haruka, Kanematsu, Yasuhisa, Kanzawa, Takao, Kimura, Kazumi, Kitayama, Jiro, Kitazono, Takanari, Koga, Masatoshi, Kondo, Rei, Kudo, Kohsuke, Kusumi, Masayoshi, Kuwahara, Ken, Matsumoto, Shoji, Matsuoka, Hideki, Mihara, Ban, Minematsu, Kazuo, Miura, Ken, Miwa, Kaori, Morita, Naomi, Mouri, Wataru, Murata, Kayo, Nagakane, Yoshinari, Nakase, Taizen, Ohara, Hiromi, Ohara, Nobuyuki, Ohnishi, Hideyuki, Ohta, Hajime, Ohtaki, Masafumi, Ohtani, Ryo, Ohtsuki, Toshiho, Ohyama, Hideo, Okada, Takashi, Okada, Yasushi, Osaki, Masato, Sakai, Nobuyuki, Sanbongi, Yoshiki, Sasaki, Naoshi, Sasaki, Makoto, Sato, Shoichiro, Seki, Kenta, Shimizu, Wataru, Shiokawa, Yoshiaki, Sozu, Takashi, Suzuki, Junichiro, Suzuki, Rieko, Takagi, Yasushi, Takizawa, Shunya, Tanahashi, Norio, Tanaka, Eijiro, Tanaka, Ryota, Tateishi, Yohei, Terada, Tomoaki, Terasaki, Tadashi, Todo, Kenichi, Tokunaga, Azusa, Toyoda, Kazunori, Tsujino, Akira, Ueda, Toshihiro, Uesaka, Yoshikazu, Uotani, Mihoko, Urabe, Takao, Watanabe, Masao, Yagita, Yoshiki, Yakushiji, Yusuke, Yamamoto, Haruko, Yasui, Keizo, Yonehara, Toshiro, Yoshimura, Sohei, Yoshimura, Shinichi, Aarnio, K., Alemseged, F., Anderson, C., Ang, T., Archer, M.L., Attia, J., Bailey, P., Balabanski, A., Barber, A., Barber, P.A., Bernhardt, J., Bivard, A., Blacker, D., Bladin, C.F., Brodtmann, A., Cadilhac, D., Campbell, B.C.V., Carey, L., Celestino, S., Chan, L., Chang, W.H., ChangI, A., Chen, C.H., Chen, C.-I., Chen, H.F., Chen, T.C., Chen, W.H., Chen, Y.Y., Cheng, C.A., Cheong, E., Chiou, Y.W., Choi, P.M., Chu, H.J., Chuang, C.S., Chung, T.C., Churilov, L., Clissold, B., Connelly, A., Coote, S., Coulton, B., Cowley, E., Cranefield, J., Curtze, S., D'Este, C., Davis, S.M., Day, S., Desmond, P.M., Dewey, H.M., Ding, C., Donnan, G.A., Drew, R., Eirola, S., Field, D., Frost, T., Garcia-Esperon, C., George, K., Gerraty, R., Grimley, R., Guo, Y.C., Hankey, G., Harvey, J., Ho, S.C., Hogan, K., Howells, D., Hsiao, P.M., Hsu, C.H., Hsu, C.T., Hsu, C.-S., Hsu, J.P., Hsu, Y.D., Hsu, Y.T., Hu, C.J., Huang, C.C., Huang, H.Y., Huang, M.Y., Huang, S.C., Huang, W.S., Jackson, D., Jeng, J.S., Jiang, S.K., Kaauwai, L., Kasari, O., King, J., Kleinig, T.J., Koivu, M., Kolbe, J., Krause, M., Kuan, C.W., Kung, W.L., Kyndt, C., Lau, C.L., Lee, A., Lee, C.Y., Lee, J.T., Lee, Y., Lee, Y.C., Levi, C., Levi, C.R., Lien, L.M., Lim, J.C., Lin, C.C., Lin, C.H., Lin, C.M., Lin, D., Liu, C.H., Liu, J., Lo, Y.C., Loh, P.S., Low, E., Lu, C.H., Lu, C.J., Lu, M.K., Ly, J., Ma, H., Macaulay, L., Macdonnell, R., Mackey, E., Macleod, M., Mahadevan, J., Maxwell, V., McCoy, R., McDonald, A., McModie, S., Meretoja, A., Mishra, S., Mitchell, P.J., Miteff, F., Moore, A., Muller, C., Ng, F., Ng, F.C., Ng, J-L., O'Brian, W., O'Collins, V., Oxley, T.J., Parsons, M.W., Patel, S., Peng, G.S., Pesavento, L., Phan, T., Rodrigues, E., Ross, Z., Sabet, A., Sallaberger, M., Salvaris, P., Shah, D., Sharma, G., Sibolt, G., Simpson, M., Singhal, S., Snow, B., Spratt, N., Stark, R., Sturm, J., Sun, M.C., Sun, Y., Sung, P.S., Sung, Y.F., Suzuki, M., Tan, M., Tang, S.C., Tatlisumak, T., Thijs, V., Tiainen, M., Tsai, C.H., Tsai, C.K., Tsai, C.L., Tsai, H.T., Tsai, L.K., Tseng, C.H., Tseng, L.T., Tsoleridis, J., Tu, H., Tu, H.T-H., Vallat, W., Virta, J., Wang, W.C., Wang, Y.T., Waters, M., Weir, L., Wijeratne, T., Williams, C., Wilson, W., Wong, A.A., Wong, K., Wu, T.Y., Wu, Y.H., Yan, B., Yang, F.C., Yang, Y.W., Yassi, N., Yeh, H.L., Yeh, J.H., Yeh, S.J., Yen, C.H., Young, D., Ysai, C.L., Zhang, W.W., Zhao, H., Zhao, L., Althaus-Knaurer, Katharina, Bendszus, Martin, Berrouschot, Jörg, Bluhmki, Erich, Bovi, Paolo, Chatellier, Gilles, Cove, Lynda, Davis, Stephen, Dixit, A., Donnan, Geoffrey, Dziewas, Rainer, Ehrenkrona, Christina, Eschenfelder, Christoph, Fatar, Marc, Francisco Arenillas, Juan, Gruber, Franz, Hacke, Werner, Kala, Lalit, Kapeller, Peter, Kaste, Markku, Kessler, Christof, Köhrmann, Martin, Laage, Rico, Lees, Kennedy R., Leys, Didier, Luna Rodriguez, Alain, Mas, Jean-Louis, Mikulik, Robert, Molina, Carlos, Muddegowda, Girish, Muir, Keith, Niederkorn, Kurt, Nuñez, Xavier, Oppenheim, Catherine, Poli, Sven, Ringleb, Peter, Schellinger, Peter, Schwab, Stefan, Serena, Joaquin, Sobesky, Jan, Steiner, Thorsten, Svenson, Ann-Sofie, Toni, Danilo, Veltkamp, Roland, von Kummer, Rüdiger, Wahlgren, Nils, Wardlaw, Joanna, Betensky, Rebecca A., Boulouis, Gregoire, Carandang, Raphael A., Copen, William A., Cougo, Pedro, Cutting, Shawna, Drake, Kendra, Ford, Andria L., Hallenbeck, John, Harris, Gordon J., Hoesch, Robert, Hsia, Amie, Kase, Carlos, Latour, Lawrence, Lauer, Arne, Lev, Michael H., Muzikansky, Alona, Nagaraja, Nandakumar, Schwamm, Lee H., Searls, Eric, Song, Shlee S., Starkman, Sidney, Warach, Steven, Wu, Ona, Yoo, Albert J., and Zand, Ramin
- Abstract
Patients who have had a stroke with unknown time of onset have been previously excluded from thrombolysis. We aimed to establish whether intravenous alteplase is safe and effective in such patients when salvageable tissue has been identified with imaging biomarkers.
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- 2020
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6. Compensation mechanism for damage from ecosystem services deterioration: constitutive characteristic
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Veklych, Oksana, Karintseva, Oleksandra, Yevdokymov, Andriy, and Guillamon-Saorin, Encarna
- Abstract
A growing attention of researchers and politicians to the processes of formation and implementation of the environmental compensation mechanism is fixed in the last decade. Environmental compensation has been viewed as a national or regional regulatory mechanism that contributes to balancing the goal of environmental conservation with the goals of sustainable socio-economic development. The literature on the ecosystem service has developed the terminology of the eco-compensation mechanism. Still, they do not define its functional structure within its framework, in particular, a compensation mechanism for damage from the deterioration of ecosystem services. We characterised this crucial but relatively understudied component of the eco-compensation mechanism and suggested a general formula for determining the magnitude of compensatory payments for damages from degradation/destruction of ecosystem services, which will help to improve the implementation of compensatory payments in decision-making as well as drive green economic activity.
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- 2020
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7. La infusión intracerebroventricular prolongada de líquido cefalorraquídeo procedente de pacientes con esclerosis lateral amiotrófica provoca cambios histológicos en el cerebro y la médula espinal de la rata similares a los hallados en la enfermedad
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Gómez-Pinedo, U., Galán, L., Yañez, M., Matias-Guiu, J., Valencia, C., Guerrero-Sola, A., Lopez-Sosa, F., Brin, J.R., Benito-Martin, M.S., Leon-Espinosa, G., Vela-Souto, A., Lendinez, C., Guillamon-Vivancos, T., Matias-Guiu, J.A., Arranz-Tagarro, J.A., Barcia, J.A., and Garcia, A.G.
- Abstract
La exposición de líquido cefalorraquídeo (LCR) de pacientes con esclerosis lateral amiotrófica (ELA) induce efectos citotóxicos en cultivos celulares de neuronas motoras in vitro.
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- 2024
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8. Methodological insights: impression management: developing and illustrating a scheme of analysis for narrative disclosures - a methodological note
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Brennan, Niamh M., Guillamon-Saorin, Encarna, and Pierce, Aileen
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Financial management -- Analysis ,Corporate image -- Management ,Self-presentation -- Analysis ,Company business management ,Banking, finance and accounting industries ,Business - Abstract
The article describes the development of a holistic score to analyze impression management and to detect bias introduced into corporate narratives by impression management. Results suggest that impression management is present in corporate financial communications that use multiple impression management techniques, so that positive information is emphasized and negative information is either understated or ignored.
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- 2009
9. Brain hemorrhage recurrence, small vessel disease type, and cerebral microbleeds
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Charidimou, Andreas, Imaizumi, Toshio, Moulin, Solene, Biffi, Alexandro, Samarasekera, Neshika, Yakushiji, Yusuke, Peeters, Andre, Vandermeeren, Yves, Laloux, Patrice, Baron, Jean-Claude, Hernandez-Guillamon, Mar, Montaner, Joan, Casolla, Barbara, Gregoire, Simone M., Kang, Dong-Wha, Kim, Jong S., Naka, H., Smith, Eric E., Viswanathan, Anand, Jäger, Hans R., Al-Shahi Salman, Rustam, Greenberg, Steven M., Cordonnier, Charlotte, and Werring, David J.
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- 2017
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10. NURR1 Involvement in Recombinant Tissue-Type Plasminogen Activator Treatment Complications After Ischemic Stroke
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Merino-Zamorano, Cristina, Hernández-Guillamon, Mar, Jullienne, Amandine, Le Béhot, Audrey, Bardou, Isabelle, Parés, Mireia, Fernández-Cadenas, Israel, Giralt, Dolors, Carrera, Caty, Ribó, Marc, Vivien, Denis, Ali, Carine, Rosell, Anna, and Montaner, Joan
- Abstract
Despite the effectiveness of recombinant tissue-type plasminogen activator (r-tPA) during the acute phase of ischemic stroke, the therapy remains limited by a narrow time window and the occurrence of occasional vascular side effects, particularly symptomatic hemorrhages. Our aim was to investigate the mechanisms underlying the endothelial damage resulting from r-tPA treatment in ischemic-like conditions.
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- 2015
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11. Segovia, siglo XV
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Javier Guillamon, Franciso
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- 2002
12. Teaching Psychobiology at a Distance
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Guillamon, Jose and Guillamon, Antonio
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Psychobiology is an area of knowledge that deals with the biological basis of behaviour. Its concretion as a specific area of study originates in the confluence and development of other areas such as physiological psychology, experimental and comparative psychology, ethology, biology and the neurosciences. For some, psychobiology would be that part of the neurosciences that deals with the study of the processes of emotion, motivation, cognition and learning. Others are of the opinion that it covers a much wider area, and that its objective is rooted in the study of all biological mechanisms that govern behaviour - and these, undertaken from a philogenetic and ontogenetic perspective.In the last decade, we have witnessed the creation of psychobiology departments throughout the world. These departments participate in the teaching of faculties of medicine, psychology, biology and zoology. In some universities, these departments even contribute to the teaching imparted by the faculties of philosophy and educational sciences. Sooner or later, the universities teaching at a distance had to consider the creation of departments of psychobiology to attend to the up-dating of the curriculum of diversive faculties.In the National University of Education at a Distance, U.N.E.D. (Madrid, Spain) the teaching of psychobiology is entrusted to a department of the same name which started during the academic year of 1982-83. Even though the experience is very short to be able to advance a complete evaluation, the difficulties encountered in the organization of the form and content of different courses imparted by the department of psychobiology (D.P.) could be useful to the reader. Therefore, these difficulties must be understood within the educational model of teaching at a distance at U.N.E.D.
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- 1985
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13. Fluorescent Molecular Peroxidation Products
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Llombart, Víctor, Dominguez, Carmen, Bustamante, Alejandro, Rodriguez-Sureda, Victor, Martín-Gallán, Pilar, Vilches, Angel, García-Berrocoso, Teresa, Penalba, Anna, Hernández-Guillamon, Mar, Rubiera, Marta, Ribó, Marc, Eschenfelder, Christoph, Giralt, Dolors, Molina, Carlos A., Alvarez-Sabín, José, Rosell, Anna, and Montaner, Joan
- Abstract
Fluorescent molecular peroxidation products (FMPPs) are considered potential markers of molecular oxidative damage and may provoke increased permeability and disruption of the blood–brain barrier. This study aimed to determine the value of FMPPs as a biomarker to predict neurological worsening related to early hemorrhagic transformation.
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- 2014
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14. Strategies for the Preparation and Concentration of Mushroom Aromatic Products
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Villares, Ana, Guillamon, Eva, Mateo-Vivaracho, Laura, D’Arrigo, Matilde, and Garcia-Lafuente, Ana
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Fungal aroma comprises at least seven chemical groups of volatile organic compounds, which are plain hydrocarbons, heterocycles, alcohols, phenols, acids and derivatives, carbonyls (aldehydes and ketones), and sulfur containing molecules. This aromatic blend provides the excellent sensory properties to produce and several strategies have been employed to create aromatic products having the aroma and taste of mushrooms and truffles. Nowadays, there are several procedures to obtain aroma concentrates. Among them, the simulation of mushroom aroma by the combination of the main substances responsible for the flavour could be an efficient strategy. Nevertheless, natural procedures are gaining more importance since the concentrate is not a synthetic product and the processes commonly involve the use of mushroom waste. In this field, the maceration with precursor molecules, such as linoleic acid, or different types of enzymes is commonly used in food industry. This article provides a wide view of the most common strategies to produce fungal aroma taking into account the main advantages and disadvantages they present. The article presents some promising patents on strategies for the preparation and concentration of mushroom aromatic products.
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- 2012
15. Ultraearly hematoma growth predicts poor outcome after acute intracerebral hemorrhage
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Rodriguez-Luna, D., Rubiera, M., Ribo, M., Coscojuela, P., Piñeiro, S., Pagola, J., Hernandez-Guillamon, M., Ibarra, B., Romero, F., Alvarez-Sabin, J., Montaner, J., and Molina, C.A.
- Abstract
To investigate the impact of the adjustment of initial intracerebral hemorrhage (ICH) volume by onset-to-imaging time (ultraearly hematoma growth uHG) on further hematoma enlargement and outcome in patients with acute ICH.
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- 2011
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16. Use of Modified Atmosphere Packaging to Preserve Mushroom Quality during Storage
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Palacios, Irene, Moro, Carlos, Lozano, Miguel, D'Arrigo, Matilde, Guillamon, Eva, Garcia-Lafuente, Ana, and Villares, Ana
- Abstract
Mushrooms have attracted much attention due to their excellent nutritional and sensory properties. However, they are highly perishable and rapidly lose their organoleptic characteristics. Many methods have been employed for mushroom storage, such as packaging, blanching, canning, or freeze drying. Among them, modified atmosphere packaging (MAP) has been widely employed for preserving fresh mushrooms. MAP provides an affordable packaging system that partly avoids enzymatic browning, fermentation and other biochemical processes by maintaining a controlled gas atmosphere. Several factors, including optimum CO2 and O2 partial pressures, permeability, package material, thickness, or product weight, must be considered in order to design a suitable modified atmosphere package for mushrooms. Thus, different strategies are available to preserve mushroom quality after harvest. The article presents some promising patents on use of modified atmosphere packaging to preserve mushroom quality during storage.
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- 2011
17. Development of Meat and Poultry Products Enriched with n-3 PUFAs and their Functional Role
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D'Arrigo, Matilde, Rostagno, Mauricio A., Villares, Ana, Guillamon, Eva, Garcia-Lafuente, Ana, and Ram, Alvaro
- Abstract
At present, foods containing n-3 polyunsaturated fatty acids (n-3 PUFAs) are being studied through clinical trials, analytical assays and meta-analysis in order to confirm their potential health benefits. Indeed, there is a continuous search for new ways to develop products rich in n-3 PUFAs. The aim of the current review is to provide a general vision of the concept of functional meat products rich in n-3 PUFAs not only concerning fishy products, but also those from enriched meat products of monogastric and ruminant animals. This document highlights the importance of n-3 PUFAs as an essential nutrient and a functional ingredient in meat products in order to prevent deficiency or even to treat pathological conditions as cancer, cardiovascular diseases, obesity, depression and childhood disorders. Ways to improve depth in this review are those made in diets for monogastric and ruminant animals that have been enriched with n-3 PUFAs and in some cases supplemented with vitamin E. This also shows that there are other techniques to improve the meat products by varying the stage of process or formulation. Both strategies have been essentially reduced n-6: n-3 recommended to values below 4. Some studies of this paper emphasize using antioxidants such as vitamin E, as a positive influence on lipid oxidative and sensory stability of meat and meat products to avoid the variation in colour, flavour, taste and texture. The review shows recent strategies to improve the quality of meat and processed meat that would allow considering them as important functional foods.
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- 2011
18. Plasma VAP-1/SSAO Activity Predicts Intracranial Hemorrhages and Adverse Neurological Outcome After Tissue Plasminogen Activator Treatment in Stroke
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Hernandez-Guillamon, Mar, Garcia-Bonilla, Lidia, Solé, Montse, Sosti, Victoria, Parés, Mireia, Campos, Mireia, Ortega-Aznar, Arantxa, Domínguez, Carmen, Rubiera, Marta, Ribó, Marc, Quintana, Manolo, Molina, Carlos A., Alvarez-Sabín, José, Rosell, Anna, Unzeta, Mercedes, and Montaner, Joan
- Abstract
Vascular adhesion protein-1 (VAP-1) is a cell surface and circulating enzyme involved in recruitment of lymphocytes and neutrophils through its semicarbazide-sensitive amine oxidase (SSAO) activity. We aimed to study plasma VAP-1/SSAO activity in relation to the risk for intracranial bleeding complications in patients with stroke treated with tissue plasminogen activator (tPA), the greatest safety concern with this treatment.
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- 2010
- Full Text
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19. Mushrooms as a Source of Anti-Inflammatory Agents
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Garcia-Lafuentea, Ana, Moro, Carlos, Villares, Ana, Guillamon, Eva, A. Rostagno, Mauricio, DArrigo, Matilde, and Alfredo Martinez, Jose
- Abstract
Inflammation is nowadays well known to be involved in the development of several chronic diseases such as arteriosclerosis, obesity, diabetes, neurodegenerative diseases, and cancer. Treatment for chronic inflammatory disorders has not been solved yet, and there is an urgent need to find new and safe anti-inflammatory preventive and therapeutic compounds. Medicinal mushrooms have been traditionally used in Asian countries to manage and treat different diseases. On the other hand, edible mushrooms have recently attracted much interest as a functional food because of their antimutagenic, anti-tumoral, anti-viral, anti-thrombotic, hypocholesterolemic, hypolipidemic, and anti-oxidant properties. Among all of these healthy properties, special attention was paid to the immunomodulatory activity of some fungal compounds such as polysaccharides, mainly -glucans. Recently, some studies have demonstrated that both whole mushrooms and extracts may show anti-inflammatory activity due to the presence of bioactive compounds. This review summarizes the most recent studies investigating immunomodulatory and especially, anti-inflammatory properties of both medicinal and edible mushrooms, the compounds putatively implicated and the mechanisms that were already established.
- Published
- 2010
20. Critical slowing down close to a global bifurcation of a curve of quasi-neutral equilibria.
- Author
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Fontich, Ernest, Guillamon, Antoni, Lázaro, J. Tomás, Alarcón, Tomás, Vidiella, Blai, and Sardanyés, Josep
- Subjects
- *
COEXISTENCE of species , *CONTINUOUS time models , *EQUILIBRIUM , *ECOSYSTEMS , *INVARIANT manifolds , *GLOBAL asymptotic stability - Abstract
Critical slowing down arises close to bifurcations and involves long transients. Despite slowing down phenomena have been widely studied in local bifurcations i.e., bifurcations of equilibrium points, less is known about transient delay phenomena close to global bifurcations. In this paper, we identify a novel mechanism of slowing down arising in the vicinity of a global bifurcation i.e., zip bifurcation, identified in a mathematical model of the dynamics of an autocatalytic replicator with an obligate parasite. Three different dynamical scenarios are first described, depending on the replication rate of cooperators, (L) , and of parasites, (K). If K < L the system is bistable and the dynamics can be either the out-competition of the parasite or the two-species extinction. When K > L the system is monostable and both species become extinct. In the case K = L coexistence of both species takes place in a Curve of Quasi-Neutral Equilibria (CQNE). The novel slowing down mechanism identified is due to an underlying ghost CQNE for the cases K ≲ L and K ≳ L. We show, both analytically and numerically, that the delays caused by the ghost CQNE follow scaling laws of the form τ ∼ | K − L | − 1 for both K ≲ L and K ≳ L. We propose the ghost CQNE as a novel transient-generator mechanism in ecological systems. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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21. Short-Term Outcomes of Transfemoral Carotid Artery Stenting and Carotid Endarterectomy in Symptomatic Patients: Data from a Multicentric Prospective Registry in Brazil
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Joviliano, Edwaldo Edner, Ribeiro, Maurício Serra, Sobreira, Marcone Lima, Moura, Regina, Geiger, Martin Andreas, Guillamon, Ana Terezinha, Regina de Oliveira Raymundo, Selma, Miquelin, Daniel Gustavo, Hafner, Ludvig, Almeida, Marcelo Jose, Oliveira, Tércio Ferreira, Dalio, Marcelo Bellini, and Yoshida, Winston Bonetti
- Abstract
Transfemoral carotid artery stenting (TF-CAS) and carotid endarterectomy (CEA) are alternative strategies for stroke prevention in patients with atherosclerotic carotid disease. Because their main objective is to prevent future ischemic events, regular reassessment of the outcomes is mandatory for providing the best therapy.
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- 2022
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22. Tissue plasminogen activator (t‐PA) promotes neutrophil degranulation and MMP‐9 release
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Cuadrado, Eloy, Ortega, Laura, Hernández‐Guillamon, Mar, Penalba, Anna, Fernández‐Cadenas, Israel, Rosell, Anna, and Montaner, Joan
- Abstract
Recombinant tissue plasminogen activator (t‐PA), the only approved stroke treatment, is used for clot lysis within the occluded brain artery. Unfortunately, matrix metalloproteinase‐9 (MMP‐9) concentration increases after t‐PA treatment and has been related to hemorrhagic transformation after ischemic stroke. Although the exact cellular source of brain MMP‐9 remains unknown, invading, inflammatory cells, such as neutrophils, release MMP‐9 to cross the blood brain barrier. Therefore, we hypothesize that the most feared side effect of stroke reperfusion therapy, brain hemorrhage, is related to t‐PA‐induced MMP‐9 release by neutrophils. We show by means of ELISA that t‐PA treatment promotes MMP‐9, MMP‐8, and tissue inhibitor metalloproteinase‐2 release from human neutrophils ex vivo within 10 and 30 min. Moreover, by zymography and Western blot, we observed that neutrophils are emptied of MMP‐9 content after t‐PA treatment at those times. Finally, total internal reflection fluorescent imaging allowed us to observe the t‐PA effect on neutrophils, showing the promotion of degranulation on these cells in vivo. Our data suggest that neutrophils are good candidates to be the main source of MMP‐9 following t‐PA stroke treatment and in consequence, partially responsible for thrombolysis‐related brain bleedings.
- Published
- 2008
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23. MMP-9–Positive Neutrophil Infiltration Is Associated to Blood–Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke
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Rosell, Anna, Cuadrado, Eloy, Ortega-Aznar, Arantxa, Hernández-Guillamon, Mar, Lo, Eng H., and Montaner, Joan
- Abstract
An abnormal expression of some matrix metalloproteinases (MMPs) is related with hemorrhagic transformation events after stroke. Our aim was to investigate MMP-2 and MMP-9 in the ischemic brain and its relation with blood–brain barrier breakdown after hemorrhagic transformation in human stroke.
- Published
- 2008
- Full Text
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24. A Molecular Method for Classifying the Genotypes Obtained in a Breeding Colony from Testicular Feminized (Tfm) Rats
- Author
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Fernandez, R., Collado, P., Garcia Doval, S., Garcia-Falgueras, A., Guillamon, A., and Pasaro, E.
- Published
- 2003
- Full Text
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25. Main findings and conclusions of the implementation of Directive 76/464/CEE concerning the monitoring of organic pollutants in surface waters (Portugal, April 1999May 2000)
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Lacorte, Sílvia, Viana, Paula, Guillamon, Míriam, Tauler, Romà, Vinhas, Tereza, and Barceló, Damià
- Abstract
The purpose of this paper is to relate the implementation of Directive 76/464/CEE concerning the survey of priority dangerous substances and indicate the main priority pollutants encountered throughout a systematic monitoring program carried out in Portugal during a period of 14 months (April 1999May 2000). Contrary to what it seems, the implementation of such a Directive is not straightforward owing to the large number of compounds and samples to be analyzed at trace levels. During this period of time, 115 priority semivolatile organic compounds (SVOCs), 41 volatile organic compounds (VOCs), six organotin compounds, 14 heavy metals, phosphate, nitrates, nitrites and ammonia were determined in 644 surface water samples (corresponding to 14 months and 46 sites). In addition, priority SVOCs were also determined in sediment, mussels and fish (muscle and liver). This paper reports the procedure and analytical tools used and necessary to determine the levels of 115 priority toxic and persistent semivolatile organic compounds selected from the EC Council Directive list (76/464/EEC). An advanced analytical protocol was developed involving enrichment of water samples in Oasis solid-phase extraction cartridges (SPE) in the Lisbon laboratory with a Gilson ASPEC XL automated extraction system and by sending the enriched cartridges to Barcelona by aeroplane at 4 °C, where elution and analysis were performed. Final determination was performed with gas chromatographyelectron ionization mass spectrometry (GC-EI-MS). Acidic herbicides were determined by liquid chromatography with diode array detection. Owing to the great amount of data generated throughout the monitoring study, statistical analysis of the more representative contaminants was performed, allowing the identification of the more relevant contamination sources, percentages of findings and the description of their temporal and spatial (geographical) distributions. Recommendations and compounds that should be included in future monitoring programs are given.
- Published
- 2001
26. The development of sex differences in the locus coeruleus of the rat
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Pinos, H., Collado, P., Rodriguez-Zafra, M., Rodriguez, C., Segovia, S., and Guillamon, A.
- Published
- 2001
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27. Quantitative analysis of polycyclic aromatic hydrocarbons in sewage sludge from wastewater treatment plants
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Perez, S., Guillamon, M., and Barcelo, D.
- Published
- 2001
- Full Text
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28. PCR differentiation of Saccharomyces cerevisiaefrom Saccharomyces bayanus/Saccharomyces pastorianususing specific primers
- Author
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Josepa, Sabaté, Guillamon, José M, and Cano, José
- Abstract
The aim of the present study was to design species‐specific primers capable of distinguishing between Saccharomyces cerevisiae, Saccharomyces bayanus/Saccharomyces pastorianus. The 5′‐specific primers were designed from the ITS‐1 region (between positions 150 and 182 from the 3′‐SSU end) and the 3′‐specific primers were located in the LSU gene (positions 560–590 from the 5′‐end of this gene). These primers were tested with different collections and wild strains of these species and the results showed that the primers were capable of distinguishing between S. cerevisiaestrains and S. bayanus/S. pastorianus. Not enough sequence differences were found between S. bayanusand S. pastorianusto design specific primers for these species using this region. This method offers an effective tool for a quick differentiation of the Saccharomycesstrains of the most common species involved in industrial processes.
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- 2000
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29. Estradiol masculinizes the posteromedial cortical nucleus of the amygdala in the rat
- Author
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Vinader-Caerols, C., Collado, P., Segovia, S., and Guillamon, A.
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- 2000
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30. Phase portrait of Hamiltonian systems with homogeneous nonlinearities
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Gasull, A., Guillamon, A., and Manosa, V.
- Published
- 2000
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31. Expression of intracellular progesterone receptors in rat brain during different reproductive states, and involvement in maternal behavior
- Author
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Numan, M., Roach, J.K., Cerro, M.C.R. del, Guillamon, A., Segovia, S., Sheehan, T.P., and Numan, M.J.
- Published
- 1999
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32. The development of brain sex differences: a multisignaling process
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Segovia, S., Guillamon, A., Cerro, M.C.R. del, Ortega, E., Perez-Laso, C., Rodriguez-Zafra, M., and Beyer, C.
- Published
- 1999
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33. Studies on keratinophilic fungi. Ix: Neoarachnotheca gen. nov. and a new species of Nannizziopsis
- Author
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Cano, J., Ulfig, K., Guillamon, J.M., Vidal, P., and Guarro, J.
- Abstract
Neoarachnotheca is proposed as a new genus of Onygenales. The outstanding generic characteristics are white, spherical ascomata with a wall formed by a network of hyphae and spherical, subhyaline ascospores with an irregular sheath. Nt. keratinophila, the type species, characterized by wavy peridial hyphae has been isolated from marine and river sediments and Myriodontium keratinophilum is its anamorph. Nannizziopsis tropicalis is proposed as a new species based on a strain isolated from soil in Burundi. RFLPs analysis of ITS and 5.8S rDNA support these proposals. The differences with related genera are discussed.
- Published
- 1997
- Full Text
- View/download PDF
34. Molecular analysis of yeast population dynamics: Effect of sulphur dioxide and inoculum on must fermentation
- Author
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Constanti, M., Reguant, C., Poblet, M., Zamora, F., Mas, A., and Guillamon, J. M.
- Published
- 1998
- Full Text
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35. Study of Perturbed Lotka–Volterra Systems Via Abelian Integrals
- Author
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Gasull, A., Guillamon, A., Li, Chengzhi, and Zhang, Zhifen
- Abstract
We consider the Lotka–Volterra system as a Hamiltonian one and study a special perturbation of it. For this perturbed system we get results on the number of limit cycles. The main tools used are Abelian integrals and degenerate Hopf bifurcation.
- Published
- 1996
- Full Text
- View/download PDF
36. Feline sporotrichosis: A case report
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Gonzalez Cabo, J. F., de las Heras Guillamon, M., Latre Cequiel, M. V., and Garcia de Jalon Ciercoles, J. A.
- Abstract
The isolation of Sporothrix schenckii from a female European cat it is described. The cat showed lengthened alopecic areas, with prominent nodules in the external surface of the thighs and abdomen. A mycological and histopathological studies of the lesions were carried out. The lesions resolved under treatment with 20% potassium iodide in doses of 0'1 ml/kg oral route in a 8 weeks period.
- Published
- 1989
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37. Estradiol masculinizes the number of accessory olfactory bulb mitral cells in the rat
- Author
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Perez-Laso, C., Segovia, S., Collado, P., Rodriguez-Zafra, M., Abril, A. Del, and Guillamon, A.
- Published
- 1997
- Full Text
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38. Development of sex differences in the bed nucleus of the accessory olfactory tract in the rat
- Author
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Collado, P., Segovia, S., and Guillamon, A.
- Published
- 1998
- Full Text
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39. An Explicit Expression of the First Liapunov and Period Constants with Applications
- Author
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Gasull, Armengol, Guillamon, Antoni, and Mañosa, Vı́ctor
- Abstract
In this paper, we study systems in the plane having a critical point with pure imaginary eigenvalues, and we search for effective conditions to discern whether this critical point is a focus or a center; in the case of it being a center, we look for additional conditions in order to be isochronous. We stress that the essential differences between the techniques used in this work and the more usual ones are basically two: the elimination of the integration constants when we consider primitives of functions (see also Remark 3.2) and the fact that we maintain the complex notation in the whole study. Thanks to these aspects, we reach with relative ease an expression of the first three Liapunov constants,v3,v5, andv7, and of the first two period ones,p2andp4, for a general system. As far as we know, this is the first time that a general and compact expression ofv7has been given. Moreover, the use of a computer algebra system is only needed in the computation ofv7andp4. These results are applied to give a classification of centers and isochronous centers for certain families of differential equations.
- Published
- 1997
- Full Text
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40. The Period Function for Hamiltonian Systems with Homogeneous Nonlinearities
- Author
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Gasull, A, Guillamon, A, Mañosa, V, and Mañosas, F
- Abstract
The paper deals with Hamiltonian systems with homogeneous nonlinearities. We prove that such systems have no isochronous centers, that the period annulus of any of its centres is either bounded or the whole plane and that the period function associated to the origin has at most one critical point.
- Published
- 1997
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41. Sodium amylobarbitone and responses to nonreward
- Author
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Feldon, J., Guillamon, A., Gray, Jeffrey A., de Wit, H., and McNaughton, N.
- Abstract
Three experiments are reported testing two alternative hypotheses concerning the behavioural effects of sodium amylobarbitone (SA): (1) that it blocks the after-effect of nonreward; (2) that it blocks conditioned frustration, elicited by stimuli associated with nonreward. In support of (2) Experiment I showed that SA given in acquisition abolished the partial reinforcement extinction effect (PREE) when rats were run at one trial a day in an alley for food reward on a continuous (CRF) or partial (PRF) reinforcement schedule. Experiment II showed that, in the goal section, the effect of the drug on the PREE was due to its presence during acquisition and was not due to state dependency; but the effect of the drug in the start section was consistent with state dependency of the PREE. In Experiment III, in opposition to (1) and again in support of (2), SA given to rats trained to show patterned running for water reward on a single alternation schedule blocked patterning by increasing running speeds on nonreward trials, not by decreasing running speeds on rewarded trials.
- Published
- 1979
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42. Transmission of the agent causing a melon yellowing disease by the greenhouse whitefly Trialeurodes vaporariorum in southeast Spain
- Author
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Soria, C., Gomez-Guillamon, M. L., and Duffus, J. E.
- Abstract
The agent causing a yellowing disease of melon (Cucumis melo), which results in severe losses in crops under plastic on the coastal plains of southeast Spain, was shown to be transmitted in a semipersistent manner by the greenhouse whitefly (Trialeurodes vaporariorum Westwood). The agent was transmitted by grafting, but not by mechanical inoculation or through seeds. The agent was acquired in the minimum period tested (2 h) and could infect plants in an infection feeding interval of 6 h.
- Published
- 1991
- Full Text
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43. Microenterprise development in Latin America – a view from the Inter-American Development Bank
- Author
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Berger, Marguerite and Guillamon, Bernardo
- Abstract
There is a change going on in the way microenterprises are viewed. No longer are they the means by which poor people scrape a living; they can also be an integral part of the economy, providing jobs and contributing to economic growth. As such, there is a potential for them becoming valuable clients of the financial institutions who choose to specialize in microenterprise servicing. This article describes the variety of ways in which banks and NGOs are attempting to provide sustainable financial services as well as business support to the microenterprise sector in Latin America. It also examines how regional banks, such as the Inter-American Development Bank (IDB) can support and encourage new initiatives by banks and NGOs, as well as reforms to the banking regulations, which will ultimately benefit the development of microenterprises.
- Published
- 1996
- Full Text
- View/download PDF
44. Molecular characterization, relatedness and antifungal susceptibility of the basidiomycetous hormographiella species and Coprinus cinereus from clinical and environmental sources
- Author
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Gené, J., Guillamon, J. M., Guarro, J., Pujol, I., and Ulfig, K.
- Abstract
Hormographiella-like strains, isolated from different natural substrates and producing sclerotia and occasionally basidiomata of Coprinus cinereus, were compared morphologically and using molecular techniques with clinical strains of Hormographiella aspergillata and H. verticillata. Analysis of restriction fragment length polymorphisms of ribosomal and mitochondrial-like DNA confirmed interspecific differences between H. aspergillata and H. verticillata, supporting the morphological data, and helped demonstrate that H. aspergillata is the anamorph of C. cinereus. The latter was confirmed also by crossing tests. The analysis of the mtDNA restriction profiles revealed intraspecific variability in C. cinereus, which allowed differentiation of clinical and environmental strains. Due to the implication of C. cinereus and Hormographiella in human opportunistic infections, the antifungal susceptibility test is included. Results show that all strains were susceptible to miconazole, itraconazole and ketoconazole but not to flucytosine and fluconazol. Susceptibility against amphotericin B was variable; while H. verticillata was susceptible, four out of seven C. cinereus strains tested were resistant.
- Published
- 1996
- Full Text
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45. Periods for transversal maps via Lefschetz numbers for periodic points
- Author
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Guillamon, A., Jarque, X., Llibre, J., Ortega, J., and Torregrosa, J.
- Abstract
Let $ f:M \to M$ map on a $ {C^1}$ is called transversal if for all $ m \in \mathbb{N}$ intersects transversally the diagonal of $ M \times M$ such that $ x$. We study the set of periods of $ f$ $ {H_0} \approx \mathbb{Q}$ $ {H_1} \approx \mathbb{Q} \oplus \mathbb{Q}$ $ {H_k} \approx \{ 0\} $.
- Published
- 1995
46. Sex differences in the vomeronasal system
- Author
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Guillamon, A. and Segovia, S.
- Published
- 1997
- Full Text
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47. Phase-amplitude dynamics in terms of extended response functions: Invariant curves and arnold tongues.
- Author
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Castejón, Oriol and Guillamon, Antoni
- Subjects
- *
INVARIANT manifolds , *DYNAMICAL systems , *CURVES , *DISCRETE systems , *DEVIATION (Statistics) , *HYPOGLOSSAL nerve - Abstract
• We construct a 2D entrainment map based on phase-amplitude response functions and study the effect of pulsed periodic inputs. • We describe the dynamics on the invariant curves of the 2D map detecting both their breakdown and inner bifurcation cascades. • We show that the 2D entrainment map tracks the phase-locking dynamics much better than the 1D map (standard phase-reduction). • We show differences in the boundaries of the Arnold tongues between the 2D entrainment map and the 1D map. • Our 2D framework can be adapted to many neuronal models and provide realistic paradigms where the 1D phase-reduction fails. Phase response curves (PRCs) have been extensively used to control the phase of oscillators under perturbations. Their main advantage is the reduction of the whole model dynamics to a single variable (phase) dynamics. However, in some adverse situations (strong inputs, high-frequency stimuli, weak convergence,...), the phase reduction does not provide enough information and, therefore, PRC lose predictive power. To overcome this shortcoming, in the last decade, new contributions have appeared that allow to reduce the system dynamics to the phase plus some transversal variable that controls the deviations from the asymptotic behaviour. We call this setting extended response functions. In particular, we single out the phase response function (PRF, a generalization of the PRC) and the amplitude response function (ARF) that account for the above-mentioned deviations from the oscillating attractor. It has been shown that in adverse situations, the PRC misestimate the phase dynamics whereas the PRF-ARF system provides accurate enough predictions. In this paper, we address the problem of studying the dynamics of the PRF-ARF systems under periodic pulsatile stimuli. This paradigm leads to a two-dimensional discrete dynamical system that we call 2D entrainment map. By using advanced methods to study invariant manifolds and the dynamics inside them, we construct an analytico-numerical method to track the invariant curves induced by the stimulus as two crucial parameters of the system increase (the strength of the input and its frequency). Our methodology also incorporates the computation of Arnold tongues associated to the 2D entrainment map. We apply the method developed to study inner dynamics of the invariant curves of a canonical type II oscillator model. We further compare the Arnold tongues of the 2D map with those obtained with the map induced only by the PRC, which give already noticeable differences. We also observe (via simulations) how high-frequency or strong enough stimuli break up the oscillatory dynamics and lead to phase-locking, which is well captured by the 2D entrainment map. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
48. INNOVATIVE PARTNERSHIPS FOR EXPORT: Latin America's Rise in the Global Partnerships Arena.
- Author
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Guillamon, Bernardo
- Subjects
- *
SUSTAINABLE development , *ECONOMIC development , *BUSINESS partnerships - Abstract
The article discusses partnerships for development in Latin America and the Caribbean. It reports that innovative models are being developed there which focus on long-term sustainability and effectiveness. The Salud Mesoamerica 2015 program is discussed as an example of this trend. It involves the Inter-American Development Bank (IDB), the Bill & Melinda Gates Foundation, the Carlos Slim Health Institute, and the government of Spain. Bernardo Guillamon, Advisor to the Office of Outreach and Partnerships at the IDB, is quoted commenting on the establishment of international benchmarks for partnerships in development.
- Published
- 2010
49. Una imagen sorprendente en tránsito baritado
- Author
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Ariza-Fernández, José Luis, Navarro-Guillamon, Laura, and Redondo-Cerezo, Eduardo
- Published
- 2016
- Full Text
- View/download PDF
50. Treatment of osteitis by excision and graft at open operations by Papineau's method
- Author
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Roy-Camille, R, Guillamon, J C, Saillant, G, Sagnet, P, Lelievre, J F, and Reignier, B.
- Published
- 1975
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