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Calvaria from six-day-old infant mice were grown on a grid culture in a chemically defined medium under varying oxygen tensions. Quantitative isotope studies demonstrated a linear association between bone resorption and oxygen tension in the physiological range. This result was supported by histological, histochemical and vital staining experiments. The clinical finding of osteoporosis in areas of hyperaemia could therefore be attributed to a rise in oxygen tension causing increased bone resorption.

Twenty-six patients with rheumatoid disease affecting the cervical spine underwent surgical treatment for neck pain, neurological deficit, or both. Atlantoaxial subluxation (n = 13), subaxial subluxation (n = 7) and vertical migration of the odontoid (n = 6) were treated. Arthrodesis with autologous bone was augmented with wire, Ransford loop, Hartshill rectangle or Magerl technique. Pain relief occurred in 92% of patients. Neurological deficit improved in 89% and was unchanged in the remainder. Radiographic stability was achieved in all but one patient. Posterior surgery effectively relieved pain and neurological deficit, and the complications encountered did not jeopardize the outcome.Keywords: Cervical spine, Rheumatoid disease, Posterior, Surgery, Fusion.

A histochemical analysis was made of 103 muscle biopsies taken from 62 patients with idiopathic club feet. Any reduction in the diameter of the muscle fibres associated with wasting of the calf muscle was recorded. Histochemical abnormalities existing in these biopsies were revealed by comparison with normal biopsies obtained from the normal legs of 13 children with unilateral deformities. No significant difference was found between the diameter of the muscle fibres taken from normal and affected legs aged under six months. This indicates that wasting of the calf muscle is due to a reduction in the number of fibres rather than their size. The muscle structure was normal excluding denervation and reinnervation. The soleus muscle in patients aged under six months contained 61 per cent Type 1 fibres in the affected legs, compared to 44.3 per cent in normal legs. Similar values were found in the normal and abnormal tibialis posterior muscles, long flexors of the toe and peroneal muscles. The change in composition of the soleus muscle and the reduction in the number of fibres may be caused by a defective neural influence on the development of the limb in club foot.

A circular arc test is described for determining the residual, or constant volume, interface strength parameters between soil and geosynthetics. The model is based on the variation of tension in a circular arc of fabric placed over a soil specimen and dead-loaded on two ends. The test method is simple and boundary conditions are well defined. The apparatus, theoretical formulation, and testing procedures are presented. The interface friction angle between dry Muskegon sand and three different materials: a cotton fabric, a fiber-glass mesh, and a nonwoven Geolon N35 filter, as determined by the circular arc test, are presented. Results of a staged circular arc test are also presented for the cotton fabric, and comparison to direct shear test results is made.

A laboratory testing apparatus is described for examining slopes subjected to seepage and stabilized by anchored geosynthetics (AGS). The AGS technique can increase the stability of cohesionless slopes such as coastal dunes against surficial erosion and shallow mass failure caused by wave action and seepage forces. In the AGS, a geosynthetic fabric is placed on the face of the slope and tensioned via anchorage to the ground. The required tension is achieved through frictional or pullout resistance of earth anchors that are fastened to the fabric and driven into the underlying soil mass. In the laboratory testing apparatus, however, AGS tensioning is provided by thin wires connected to rigid steel tubes that exert line loads on the fabric. The wires in turn are connected to dead weights “beneath” the slope that simulate anchor loads. The prototype slopes are failed by uniformly decreasing anchor loads while maintaining the seepage gradient and orientation constant. Very good agreement was observed between experimental results and theoretical predictions of the failure mode and the average AGS loads at failure.

This paper describes the measurement of the influence of capillary effects on the dynamic shear modulus of partially saturated sands. A Hall-type resonant column apparatus was used to perform the experiments. The materials tested included natural angular and subrounded sands, angular and subrounded sands with specified artificial gradations, and uniform angular and subrounded sands with various minus No. 400 sieve size fractions.Capillary stresses can significantly increase the shear modulus of unsaturated sands. Void ratio, confining pressure, degree of saturation, grain shape, and grain-size distribution are the primary factors affecting the shear modulus of partially saturated sands.

The results of excision arthroplasty on forty hips in thirty-two patients have been studied by personal review. The mean follow-up was ten years and the results were graded in the Lazansky system. The outcome was fairly predictable, most patients achieving a fair to good result. The patients were satisfied with the operation in unilateral cases as a secondary operation, but it was generally unsatisfactory as a primary procedure or when performed bilaterally. Pain relief was satisfactory, and previously infected hips achieved sound wound and bone healing. Half could walk with no aid or one stick. No correlation could be found between the radiological appearances and the quality of the result.