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Allogeneic haematopoietic stem cell transplantation (allo-HSCT) entails long-term morbidities that impair survivors’ quality of life through broad physical and psychosocial sequelae. Current data and survival measurements may be inadequate for contemporary Australian allo-HSCT recipients. This study sought to comprehensively describe survivorship in an up-to-date, local setting through validated measurements and a novel questionnaire designed to complement and address limitations of current instruments. All adults who received an allo-HSCT between 2000 and 2012 in New South Wales were eligible and included, if alive, those literate and consenting to the study, which encompassed seven survey instruments. Four hundred and forty-three survivors participated, which is 76% of contactable (n=583) and 66% of eligible survivors (n=669). Chronic GVHD (cGVHD) and co-morbidity rates were similar to published data. Noteworthy results include prevalent sexual dysfunction (66% females, 52% males), loss of income (low income increased from 21 to 36%, P<0.001) and employment (full-time employment fell from 64 to 33%, P<0.001), suboptimal vaccination (31% complete), and health screening (≈50%). Risk factors for poor vaccination and health screening were cGVHD, younger age, less education, rural/regional residence and transplantation <2 years. This study suggests that improvement in survivorship may necessitate structural changes in the current delivery of health services.

AbstractSeven years of field evaluation has shown the alfalfa blotch leafminer, Agromyza frontella(Rondani), to be of minor economic importance in Vermont. Although response to certain insecticidal treatments resulted in highly significant reduction in leaf mining at time of cut, no other differences were shown. Analyses of fiber content as measured by lignin, cell wall constituents, acid detergent fiber, quality as measured by % protein and % digestibility, and yields in dry weight (kg/ha) showed no significant differences. Comparison of leaflet dehiscence from field-cured and baled samples failed to indicate differences between blotched and healthy alfalfa.Two imported parasite species, Chrysocharis punctifaciesDelucchi and Dacnusa dryas(Nixon), are established within the state; we predict that these parasites combined with native species will effect a decline in alfalfa blotch leafminer levels below any conceivable economic threshold.