1. Impact of haemoglobin A1c on wound infection in patients with diabetes with implanted synthetic graft
- Author
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Matić, Predrag, Atanasijević, Igor, Stojković, Vera Maravić, Soldatović, Ivan, Tanasković, Slobodan, Babić, Srđan, Gajin, Predrag, Lozuk, Branko, Vučurević, Goran, Đoković, Aleksandra, Živić, Rastko, Đulejić, Vuk, Nešković, Mihailo, Babić, Aleksandar, and Ilijevski, Nenad
- Abstract
Objective:The aim of this study was to assess the relationship between haemoglobin A1c (HbA1c) values and operative wound infectionMethod:During the period from 2013–2016, consecutive patients with type 2 diabetes were prospectively evaluated. Data were retrospectively analysed. All included patients were admitted for an elective surgical procedure, requiring the use of prosthetic graft in a groin wound. The patients were divided into two groups according to their preoperative HbA1c values. The main outcome was groin wound infection. The association between preoperative long-term glycoregulation and wound infection was evaluated, as well as the impact of postoperative glycaemic values, regardless of the level of HbA1c.Results:Of the 93 participating patients, wound infection occurred in 20 (21.5%). Wound infection occurred in 28.2% of patients with uncontrolled diabetes (HbA1c >7%) and 16.7% of patients with controlled diabetes (HbA1c <7%); however, the difference did not reach statistical significance (p=0.181). In regression modelling, operative time (p=0.042) was a significant predictor of wound infection, while patients' age (p=0.056) was on the borderline of statistical significance. Females had a higher probability for wound infection (odds ratio (OR): 1.739; 95% confidence interval (CI):0.483–6.265), but there was no statistical significance (p=0.397). Patients with elevated levels of HbA1c had a higher chance of wound infection compared with patients with controlled diabetes (OR: 2.243; 95% CI: 0.749–6.716), nevertheless, this was not statistically significant (p=0.149).Conclusion:We found no statistically significant correlation between elevated values of preoperative HbA1c and postoperative groin wound infection.
- Published
- 2024
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