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To achieve this feat, the placenta oversees the complete remodelling of the nearly 150 spiral arteries - small, coiled blood vessels in the uterus - that supply it with blood. The placenta is part of the fetus, which means its genome is different to the genome of the cells of the uterus. As the popularity of the hypothesis has grown, some researchers have begun responding to critics by exploring exactly how the placenta might influence fetal development and long-term health. Then there is placenta accreta, a serious condition in which a newly formed placenta doesn't stop growing after invading the uterus. [Extracted from the article]

The placenta is part of the fetus,which means its genome is different to the genome of thecells of the uterus. Features Feature We may lose our placenta at birth, but it continues toinfluence our health and well-being farinto our life, finds Jasmin Fox-Skelly AS WE emerged into the world as newborns, each of us lostsomething important: a body part that had provided us withoxygen and nutrients, removed waste products and keptpathogens at bay. Then there is placenta accreta, a serious condition in which anewly formed placenta doesn't stop growing after invadingthe uterus. Placenta problems Take pre-eclampsia, which each year leads to the deaths of70,000 women and is also a factor in 500,000 stillbirths. [Extracted from the article]

The article features Raul Gomez, a craftsman who makes fetal models by hand and whose works are on display at Minnesota Citizens Concerned for Life (MCCL) March for Life. Topics discussed include his work at Heritage House, which sells prolife resources and products, how MCCL volunteers came up with the idea for the display, and reaction of people who attended the March for Life when they saw the models on display.

A clinical trial, NCT06634407, is being conducted to evaluate the outcome of percutaneous transcatheter closure of patent ductus arteriosus in children. The trial is titled "Transcatheter Closure of Patent Ductus Arteriosus. Experience of Pediatric Cardiology Unit-Assiut University Hospital." It aims to assess the effectiveness of transcatheter closure in pediatric patients with patent ductus arteriosus. [Extracted from the article]

A new report discusses research findings on fetal heart rate monitoring methods, which are crucial for assessing fetal health during prenatal care. The review examines both traditional and modern monitoring techniques, such as electrocardiography and cardiotocography, as well as the latest developments in textile-based wearables for fetal heart rate monitoring. These innovative devices have the potential to provide continuous data collection and non-intrusive options for expectant mothers, but there are challenges related to signal quality, user compliance, and data interpretation. The research suggests that these technologies could change the landscape of prenatal monitoring by offering more individualized options for fetal health surveillance. [Extracted from the article]

A recent report from Harvard Medical School explores the relationship between placental anomalies and fetal congenital heart disease (FCHD). The study found that FCHD placentas had higher rates of maternal vascular malperfusion and cord anomalies compared to non-FCHD placentas. However, the prevalence of vascular malperfusion did not differ based on the type of FCHD, suggesting that the type of congenital heart disease does not predict the likelihood of placental vascular dysfunction. The researchers recommend further investigation into the placental-fetal heart axis in FCHD due to the importance of placental health. [Extracted from the article]

A preprint abstract from medrxiv.org discusses the development of a single-stage detection model for fetal cardiac ultrasound standard planes (FCUM) to improve the accuracy and efficiency of diagnosis. The model incorporates a hybrid attention mechanism module and a multi-layer residual network for feature fusion, resulting in improved detection and classification accuracy. The model was tested on a diverse set of fetal cardiac ultrasound images and outperformed baseline models in both detection and classification accuracy. It is important to note that this preprint has not yet undergone peer review. [Extracted from the article]

A patent application titled "Device For Positioning A Fetal Heart Rate Transducer" has been published online. The invention aims to provide a device that can more reliably hold a fetal heart rate transducer in position on a pregnant woman's abdomen. The device consists of a body with a non-planar lower surface that includes a protruding portion to engage the transducer and apply pressure to a selected area on its upper surface. The device can be held in place with a belt if necessary. The invention offers a potential solution to the problem of losing a fetal heart rate signal during monitoring, which can lead to delays in identifying abnormalities. [Extracted from the article]

Researchers from the University of Sri Jayewardenepura have developed a cost-effective and user-friendly wearable device for monitoring fetal movement and distress during the final trimester of pregnancy. The device utilizes a microcontroller, accelerometer, and a specialized fetal phonocardiography acquisition board to accurately detect fetal movement and monitor fetal heart rhythm. It also includes a GSM-based alert system for instant distress notifications to the mother, proxy, and emergency services. The system achieved zero false negatives in detecting fetal movements and demonstrated efficacy in identifying fetal distress. This research offers a promising solution for non-intrusive fetal monitoring at home. [Extracted from the article]

A recent study conducted at the University of Health Sciences Turkey examined the effectiveness and safety of transcatheter closure of patent ductus arteriosus (PDA) in children using Amplatzer duct occluder I (ADO I) and Amplatzer duct occluder II (ADO II) devices. The study analyzed cases from January 2010 to January 2023 and found that PDA closure was successfully performed in 99.1% of the cases. Minimal residual shunt and major complications were reported in a small number of patients. The study concluded that transcatheter PDA closure using ADO I and ADO II devices is an effective and safe method with low complication rates in children. [Extracted from the article]

The article presents a case study of a osteogenesis imperfecta type II in a one-day-old infant with multiple severe complications. The study highlights the presence of patent ductus arteriosus, persistent pulmonary hypertension, sepsis, and severe thrombocytopenia, which contributed to the infant's early death. Topics include the clinical presentation of osteogenesis imperfecta type II, associated severe conditions, and diagnostic approaches.

The article explores the role of OPA1, an inner mitochondrial membrane protein, in maintaining cardiac function and providing protection against cardiac injuries such as ischemia-reperfusion. Topics discussed include the correlation between OPA1 levels and various cardiac gene signatures, experimental findings from OPA1-overexpressing mice, and the impact of OPA1 on cardiac function and fibrosis.

A study conducted at the First Affiliated Hospital of Soochow University in Suzhou, China, has evaluated the use of fetal heart quantification (Fetal HQ) technology to assess the structure and function of the fetal heart during mid to late pregnancy. The study analyzed various parameters such as heart size, ventricular function, and morphology in 500 normal pregnant fetuses. The findings showed that Fetal HQ can effectively evaluate the growth and development of the fetal heart in the second and third trimesters. This research provides a foundation for the clinical application of fetal cardiac speckle tracking technology. [Extracted from the article]

A recent study conducted by researchers at Tehran University of Medical Sciences in Iran focused on ectopic pregnancy, specifically pregnancy in the rudimentary horn of the unicornuate uterus. The researchers reported a case of a 35-year-old Iranian woman who experienced abdominal pain and was diagnosed with an ectopic pregnancy in the rudimentary horn. The pregnancy was successfully treated through laparoscopy, and the researchers emphasized the importance of increasing awareness about this rare condition to facilitate early diagnosis and prevent complications. The full study can be accessed for free online. [Extracted from the article]

The article investigates the role of fetal microchimerisms in maternal heart tissue following myocardial infarction. Topics discussed include the presence of these cells in the heart, their potential impact on cardiac repair, and the effects of eliminating microchimerisms on cardiac function in a mouse model.

Researchers from the University of California have conducted a narrative review on the echocardiographic evaluation of patent ductus arteriosus (PDA) in preterm infants. PDA is prevalent among extremely preterm infants and is associated with increased mortality and morbidities such as intraventricular hemorrhage and chronic lung disease. The review emphasizes the importance of assessing the hemodynamic impact of PDA rather than just its presence or size. The researchers also discuss the use of lung ultrasound as an adjunct to evaluate the impact of PDA on the lungs. This research provides valuable insights into the management of PDA in preterm infants. [Extracted from the article]

A patent has been issued for a safe and reliable method of transabdominal fetal oximetry, which measures the oxygen saturation level of a fetus during labor. The technology involves shining near infrared light into the maternal abdomen and analyzing the diffused scattered light to estimate fetal oxygen saturation. The patent describes systems and methods for balancing the need for a strong signal with patient safety, ensuring that the skin temperature of the maternal abdomen does not rise to unsafe levels. The system utilizes a combination of light sources, photodetectors, and processing mechanisms to determine fetal blood oxygenation levels and present a unified indication of fetal health. [Extracted from the article]

A recent study conducted by researchers at Dalhousie University in Nova Scotia, Canada, has examined the treatment of patent ductus arteriosus (PDA) in extremely preterm infants. PDA is a common cardiovascular problem in this population and is associated with poor clinical outcomes. The study aims to determine the feasibility of a larger randomized controlled trial to assess the effectiveness of early pharmacotherapeutic treatment for clinically symptomatic and echocardiography-confirmed PDA. The study is being conducted in seven neonatal intensive care units in Canada and the USA, with a target of 100 randomized infants. The results of the study will be presented at national and international meetings, published in peer-reviewed journals, and incorporated into existing systematic reviews. [Extracted from the article]

Researchers from Charles University in Prague, Czech Republic, have conducted a study on the electrical remodeling of the atrioventricular (AV) junction in chick embryonic hearts. The study aimed to understand the development and functionality of accessory pathways (APs) that provide additional electrical connections between the atria and ventricles. The researchers used an optical mapping approach to analyze the number and functionality of APs in different positions around the annulus fibrosus. They observed a regression of APs with maturation and documented accessory myocardial AV connections even after hatching. The study highlights the importance of electrophysiological evaluation in studying AP formation. [Extracted from the article]

A study conducted by researchers at Fujian Medical University in Quanzhou, China, has found that the right ventricular fetal tricuspid annular plane systolic excursion index (FTI) can be used to evaluate fetal cardiac function in pregnant women with hypertensive disorders. The study measured the FTI in 208 normal fetuses between 20 and 40 weeks of gestation and found that the FTI remained relatively constant throughout different gestational weeks. However, as the severity of hypertensive disorders increased, the FTI gradually decreased. The study suggests that the FTI can be a useful tool for evaluating fetal cardiac function in pregnant women with hypertensive disorders. [Extracted from the article]

A patent application titled "Oxymetry Device And Method For Measuring Fetus Oxygen Levels During Labor" has been published online by the US Patent and Trademark Office. The patent application, filed by inventors Roy Mizrachi and Roy Nissim, and assigned to Signalife Ltd., describes a sensor module that can be attached to a mammalian fetus, such as to the forehead, in a non-invasive manner. The sensor module includes multiple light sources of different wavelengths and at least one optical sensor, and a processing unit to control the light sources and process the signals. The device aims to provide accurate measurements of fetal oxygen levels during labor. [Extracted from the article]

A recent study conducted by the Division of Pediatric Cardiology has provided new data on patent ductus arteriosus (PDA). The study found that percutaneous device occlusion is the current standard of care for most cases of PDA. However, in some cases, device-related left pulmonary artery stenosis can occur, requiring stent placement to relieve the obstruction. The study presents a series of four patients who required left pulmonary stenting after ductus arteriosus device closure and includes a review of the current evidence. For more information, the full article can be accessed through Case Reports in Cardiology. [Extracted from the article]

A recent study conducted by researchers at Columbia University explored the relationship between fetal heart rate (HR) and heart rate variability (HRV) with the functional connectivity of the brainstem, hypothalamus, and dorsal anterior cingulate cortex (dACC) in newborns. The study found that fetal HR and HRV were associated with the connectivity of these brain regions, which are involved in behavioral and emotional regulation. This research provides a foundation for future studies on the regulation of behavior and physiology in fetuses and infants. The study was funded by the NIH and has been peer-reviewed. [Extracted from the article]

A study conducted by researchers at China University of Petroleum in Shandong, People's Republic of China, has developed a new method for recognizing fetal congenital heart disease (CHD) using ultrasound images. The researchers propose a multi-scale gated axial-transformer network (MSGATNet) to capture fetal four-chamber semantic information and a SPReCHD: four-chamber semantic parsing network to segment and locate four-chamber arbitrary contours. The study found that their method achieved a high precision of 95.92%, a recall of 94%, an accuracy of 95%, and a F-1 score of 94.95% in recognizing fetal CHD, significantly improving the prenatal detection rate. This research has been peer-reviewed and published in the IEEE Journal of Biomedical and Health Informatics. [Extracted from the article]

The US Patent and Trademark Office has published a patent application for a closure system designed to close holes or ducts in heart tissue. The system, invented by Harutoshi UCHIDA, includes a catheter and a closure device consisting of a resin-containing extension part. The patent application also outlines a manufacturing method that involves using a learning model to design the closure device based on the shape and position of the hole or duct. The closure device may include additional features such as a heart rate sensor or a power generating element. This system aims to address issues associated with existing closure devices and provide an effective solution for closing various types of holes or ducts in the heart. [Extracted from the article]

A recent study conducted in Manipur, India, examined the variations in the branching pattern of the aortic arch in human fetal hearts. The study, which involved 30 stillborn human fetuses, found that the classical pattern of three branches of the arch of the aorta was present in 76.66% of cases. However, in the remaining cases, two different types of variations were observed. The researchers concluded that understanding these variations is important for clinicians. For more information, readers can refer to the Journal of Research in Applied and Basic Medical Sciences. [Extracted from the article]

Researchers from the University of Melbourne have published a new study on fetal heart rate (FHR) and its potential for detecting fetal compromise. The study proposes a novel FHR evaluation method using an input length invariant deep learning model (FHR-LINet) to progressively evaluate FHR as labor progresses and achieve rapid detection of fetal compromise. The researchers found that their approach resulted in a 25% reduction in the time taken to detect fetal compromise compared to existing methods, while achieving high true positive rates. This diagnostic system could potentially enable earlier intervention for fetal compromise and improve clinical outcomes. [Extracted from the article]

A recent study conducted at the Royal Hospital in Muscat, Oman, used Four-Dimensional Magnetic Resonance Imaging (4D Flow MRI) to assess the effects of post-patent ductus arteriosus (PDA) stent insertion on pulmonary flow in neonates with duct-dependent pulmonary circulation. The study found that the growth rate of the left pulmonary artery (LPA) was lower than that of the right pulmonary artery (RPA), and the indexed flow in both arteries decreased after 6 months, indicating reduced stent patency. The researchers concluded that these findings can provide valuable insights for future management decisions. The full article can be accessed for free through the provided link. [Extracted from the article]

A recent study conducted at Northwest Women's and Children's Hospital in Shaanxi, China, has provided new insights into the diagnosis of a rare vascular malformation called bilateral ductus arteriosus (BDA). The study describes a case of a fetus with BDA and right aortic arch mirror-image branching combined with congenital heart disease. The researchers used various imaging techniques, including 2D grayscale, color Doppler flow imaging, and four-dimensional color Doppler imaging, to make the diagnosis. The findings highlight the importance of prenatal ultrasound in diagnosing BDA and suggest that a combination of imaging techniques is necessary for accurate scanning. [Extracted from the article]

Researchers at Gachon University in Seongnam, South Korea have conducted a study on machine learning techniques for fetal health prediction using bio-signal cardiotocography. Cardiotocography measures the fetal heart rate during pregnancy and provides important data for detecting abnormalities. The traditional method of interpreting cardiotocography results is prone to human error, so machine learning techniques were used to improve accuracy. The study found that the proposed model using federated machine learning achieved a prediction accuracy of 99.06% and a misprediction rate of 0.94%, outperforming the K-nearest neighbor technique. This research has been peer-reviewed and published in Computers Materials & Continua. [Extracted from the article]

A recent report from Vanderbilt University School of Medicine discusses the discovery of a new inhibitor, VU0542270, which selectively targets vascular KATP channels. These channels play a critical role in regulating blood flow and blood pressure, making them attractive targets for cardiovascular disorder treatments. The research team screened thousands of compounds and found that VU0542270 inhibits Kir6.1/SUR2B channels with high selectivity. While further research is needed, this discovery offers hope for the development of cardiovascular therapeutics targeting Kir6.1/SUR2B. [Extracted from the article]

A recent study conducted by researchers at Capital Medical University in Beijing, China, explored the relationship between maternal exposure to ozone (O3) and conotruncal heart defects (CTDs) in fetuses. The study found that elevated maternal exposure to O3 during pregnancy, particularly in the perinatal period, was associated with an increased risk of fetal CTDs. The research suggests that further longitudinal analyses are needed to validate these results. This study provides valuable insights into the potential impact of environmental factors on heart defects in China. [Extracted from the article]

A clinical trial, NCT06392555, has been launched to evaluate the clinical performance of a device in identifying suspicious radiographic findings in fetal heart ultrasound video clips. The trial will assess the impact of the device on reader performance during second trimester anatomic ultrasound examinations. The study is observational and will involve a fully-crossed, multiple-reader multiple-case (MRMC) design. The trial is not yet recruiting participants and is expected to be completed by July 2024. [Extracted from the article]

A recent study conducted at Hunan University in China has developed a model for detecting fetal cardiac health using ultrasound imaging. The researchers propose a single-stage fetal cardiac ultrasound standard plane detection model (FCUM) based on multitask learning and a hybrid attention mechanism to assist sonographers in diagnosis. The model outperformed baseline models in terms of detection precision and classification accuracy. This research provides valuable insights into improving the efficiency and accuracy of fetal cardiac ultrasound diagnosis. [Extracted from the article]

A recent report from the University of Alabama Birmingham discusses findings in stem cell research. The researchers used single-nucleus RNA sequencing data to analyze cardiomyocyte subpopulations in fetal pigs and pigs that underwent various surgical procedures. They identified clusters of cardiomyocytes that were primed to proliferate in response to myocardial infarction and were able to distinguish between cardiomyocytes in different phases of the cell cycle. The study also identified transcription factors that were more abundantly expressed in regenerative hearts. The research provides insights into cell cycle activity in cardiomyocytes and may have implications for regenerative medicine. [Extracted from the article]

This document provides information about a clinical study comparing the effectiveness of two different drug combinations for pain management during elective caesarean deliveries. The study involves female participants who meet specific criteria and aims to assess the occurrence of pain and side effects during the procedure. The study is currently in the recruitment phase and is expected to be completed by September 2024. The responsible party for the study is Sujan Dhakal, MD, from the Tribhuvan University Teaching Hospital. [Extracted from the article]

A scoping review conducted by researchers at the University of Porto in Portugal examined the preprocessing techniques used in analyzing fetal heart rate (FHR) signals. The review found that FHR signals are often affected by contaminants, necessitating preprocessing methods for accurate analysis. The researchers identified prevalent approaches for detecting and correcting poor signal quality events, such as analyzing deviations from neighboring samples and using interpolation techniques. However, there is a lack of consensus regarding the definition of missing samples, outliers, and artifacts. The study highlights the need for standardizing FHR signal preprocessing techniques to improve diagnostic accuracy and calls for future research to evaluate and enhance these methods. [Extracted from the article]

Researchers from the Nemours Cardiac Center in Wilmington, Delaware have conducted a study on the developmental significance of aberrant subclavian artery (ASCA) in interrupted aortic arch (IAA) with aortic/subaortic obstruction. The study focused on newborns with prenatally diagnosed isolated IAA and found that the presence of ASCA was associated with larger patent ductus arteriosus (PDACSA), suggesting an adaptive enlargement of the ductus arteriosus and ASCA in response to reduced antegrade flow across small aortic valve opening (AVOCSA), which may be augmenting cerebral blood flow. The research concluded that preservation of cerebral blood flow may be another important determinant affecting embryonic cardiovascular development. [Extracted from the article]

A case report from the National Institute of Cardiovascular Diseases in Karachi, Pakistan, discusses a rare finding of a massive left pulmonary artery aneurysm (PAA) with a co-existing patent ductus arteriosus (PDA) in a five-year-old girl. The girl presented with symptoms such as palpitations, fatigue, fever, cyanosis, and vomiting. Diagnostic tests confirmed the presence of a PDA and a large aneurysm in the left pulmonary artery. The aneurysm was successfully treated through surgery, and the patient is currently doing well during follow-up visits. This research has been peer-reviewed and published in the Journal of the Pakistan Medical Association. [Extracted from the article]

A recent study conducted by researchers at the University of Houston explores the noninvasive monitoring of cardiac development in mouse models. The study focuses on the challenges of analyzing embryonic cardiac models due to their small size and fast motion. The researchers developed a real-time volumetric optoacoustic spectroscopy (VOS) platform that allows for high-resolution visualization of the embryonic heart and quantification of cardiac dynamics. This technology has the potential to improve our understanding of mammalian heart development and aid in the diagnosis and prevention of congenital heart disease. [Extracted from the article]

A study conducted at Karolinska University Hospital in Stockholm, Sweden explored the experiences of parents who monitored the fetal heart rhythm at home. The study focused on women with anti-SSA/Ro52 autoantibodies, who have a 2%-3% risk of giving birth to a child with congenital heart block. The research found that home monitoring was not seen as complicated or burdensome by the parents, and it helped them develop a bond with their expected child. However, there was an underlying tension during the risk period. The study suggests that home monitoring should be considered an important part of care for mothers at risk of giving birth to a child with congenital heart block. [Extracted from the article]

This article discusses a case report on patent ductus arteriosus (PDA), a congenital heart defect that is uncommon in adult patients and typically presents with atrial fibrillation. The report focuses on a 75-year-old woman who was admitted to the cardiology department due to atrial fibrillation, dyspnea, and exercise intolerance. The presence of PDA was detected through echocardiography and confirmed using ECG-gated CT angiography. The study highlights the imaging features of PDA in an elderly patient who presented with atrial fibrillation. For more information, readers can refer to the original article published in The Egyptian Journal of Radiology and Nuclear Medicine. [Extracted from the article]

Researchers from the Polish Mother's Memorial Hospital Research Institute in Lodz, Poland, have conducted a review of recent research on the potential impact of a pregnant woman's microbiota on the development of fetal heart defects. The study explores the complex interactions between the microbiota and human health, particularly in the context of perinatal medicine and neonatology. The researchers discuss the role of dysbiosis and potential intervention strategies, including the use of probiotics and diet to optimize the maternal microbiota. The findings provide valuable insights into the relationship between a pregnant woman's microbiota and fetal heart defects. [Extracted from the article]

A preprint abstract from biorxiv.org discusses the spatial dynamics of the developing human heart. The study used spatial and single-cell measurements to explore the early stages of human cardiogenesis. By analyzing thousands of cells and tissue regions, the researchers identified different cell states and mapped them to specific cardiac niches. The study provides new insights into the development of the cardiac pacemaker-conduction system, heart valves, atrial septum, cardiac fibroblast population, cardiac autonomic innervation, and chromaffin cells. The research aims to contribute to a better understanding of the genetic causes of heart disease. Please note that this preprint has not yet undergone peer review. [Extracted from the article]

A recent study conducted at the Bambino Gesu Children's Hospital in Rome, Italy, analyzed the prevalence of heart defects in patients with Sotos syndrome. Sotos syndrome is a genetic condition characterized by overgrowth, developmental delays, and facial features caused by specific gene variants. The study found that 60% of the patients with Sotos syndrome had heart defects, including septal defects, aortic anomalies, and patent ductus arteriosus. The prevalence of heart defects was similar in patients with gene mutations and those with gene deletions. The researchers recommend that patients with Sotos syndrome undergo thorough cardiac evaluations and receive specialized cardiological follow-up care. [Extracted from the article]

A recent study conducted at the University of Iowa examined the safety and feasibility of percutaneous closure of patent ductus arteriosus (PDA) in infants weighing 2 kg or less. The study, which used data from the IMPACT Registry, found that percutaneous PDA closure is a safe and feasible procedure in these infants, with a low incidence of technical failure and major adverse events. The incidence of major adverse events has decreased over time and is associated with individual center case volumes and expertise. This research provides valuable insights into the treatment of PDA in neonates. [Extracted from the article]

A study conducted at the National University of Singapore Hospital aimed to determine the prevalence and characteristics of major fetal congenital heart diseases (CHDs) diagnosed during routine second-trimester obstetric scans. The study found that out of 20,031 screened pregnancies, 0.53% had major fetal CHDs, with the most common subtypes being coarctation of the aorta, transposition of the great arteries, tetralogy of Fallot, and univentricular hearts. Confirmatory genetic testing revealed abnormalities in about a quarter of cases, with 22q microdeletion being the most common. At 4 years old, 43.2% of offspring had no medical or developmental issues, 20.0% had mild issues, 21.5% had major issues, and 12.3% had deceased. The study concluded that future research should explore the use of chromosomal microarray and next-generation sequencing in diagnosing CHDs. [Extracted from the article]

Researchers at the University of Ciencias Medicas have conducted a study on the influence of NeuroEPO, a type of erythropoietin therapy, on the fetal heart in a rat model of placental insufficiency. Placental insufficiency is a common cause of intrauterine growth retardation, which can lead to cardiovascular problems. The study found that the administration of NeuroEPO improved fetal weight and helped maintain a balanced development of the fetal heart. However, the fetal weight did not reach the same level as the control group. This research suggests that NeuroEPO may have cytoprotective effects on the fetal heart. [Extracted from the article]

A recent report from the Department of Cardiovascular Medicine discusses the relationship between patent ductus arteriosus (PDA) and Takotsubo syndrome (TTS), also known as "broken heart syndrome." TTS is a form of acute heart failure that primarily affects young to middle-aged individuals, particularly women. While emotional or physical stressors often trigger TTS, rare cases have been linked to interventional procedures for congenital heart disease. The report emphasizes the importance of understanding the multifaceted aspects of TTS, including autonomic nerve function, genetic factors, hormonal influences, and inflammatory processes, in order to improve clinical approaches and therapies. The analysis of a TTS case aims to enhance the understanding of the syndrome among primary care physicians and prevent misdiagnosis. [Extracted from the article]