395 results on '"Felix, M."'
Search Results
2. Computational Decision Support for PE Diagnosis based on Ventilation Perfusion Ratio
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Vogt, Julia Katharina, Vogt, Wolfgang Kurt, Heinzel, Alexander, and Mottaghy, Felix M.
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- 2024
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3. DUAL-MIMICRY OF WASPS BY THE NEOTROPICAL LEAFHOPPER PROPETES SCHMIDTI MELICHAR WITH A DESCRIPTION OF ITS FEMALE (HEMIPTERA : CICADELLIDAE : CICADELLIN AE)
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Takiya, D M, Mejdalani, G, Felix, M, and BioStor
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- 1999
4. A new species of the neotropical genus Lissoscarta Stål (Homoptera: Cicadellidae: Cicadellinae) that mimics wasps
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Mejdalani, G, Felix, M, and BioStor
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- 1997
5. Making low-carbon energy sustainable
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Grubert, Emily, Luz Benites Lazaro, Lira, Popp, Alexander, Merfort, Leon, Luo, Tianyi, Kati, Vassiliki, Meshram, Pratima, Dorn, Felix M., and Hernández, Diana
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Low-carbon energy capacity continues to grow, facilitating the much-needed transition away from fossil fuels. However, broader sustainability issues remain. This Voices asks: what barriers continue to obstruct a truly sustainable energy transition?
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- 2024
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6. Escape Me If You Can: How AI Reshapes News Organisations’ Dependency on Platform Companies
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Simon, Felix M.
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AbstractPlatform companies play a crucial role in the creation, dissemination, and business of news. They are also central actors in artificial intelligence (AI) which has led some to argue that the increasing use of AI in journalism may heighten the news industry’s dependence on platform companies. This article evaluates this argument. Drawing on 121 interviews with news workers at 33 leading publishers in the US, UK, and Germany, as well as 31 expert interviews, and secondary material it finds that AI reshapes the dependency of publishers on platform companies by exacerbating existing dependencies in distribution and creating new dependencies in production. News organisations rely on platforms for AI for various reasons, such as high development costs, lack of resources, and varying visions over their mission. The findings show that while increasing dependence on platforms is acknowledged, there is disagreement over its extent and impact. The reliance on platforms’ AI shows isomorphic tendencies and potentially limits publishers’ autonomy.
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- 2024
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7. Efficiency of working coveralls and chemical resistant gloves in reducing operator exposure to pesticides
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Kuster, Christian J., Kluxen, Felix M., Felkers, Edgars, Morgan, Neil, Hewitt, Nicola J., and Durand-Reville, Julien
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Personal Protective Equipment (PPE) is used to reduce exposure when working with chemicals. For pesticides, exposure scenarios comprise mixing and loading (M&L) and application. The exposure prediction model recommended by European regulatory agencies for operator risk assessments—the Agricultural Operator Exposure Model (AOEM) – is based on 48 operator exposure studies involving over 500 professional operators from 10 European countries in typical working situations to assess exposure under realistic field conditions. We used the AOEM data to assess the efficiency of exposure reduction resulting from wearing chemical-resistant nitrile gloves and non-certified working coveralls during M&L (tank and backpack sprayer), applications using groundboom and airblast spraying, and outdoor and indoor (greenhouse) applications using handheld sprayers. All studies indicated consistent and high exposure reduction > 90% for gloves and non-certified coveralls across all investigated scenarios. Exceptions were almost exclusively observed when an operator incorrectly used the PPE. The mean exposure reduction from all operators, including those that used PPE incorrectly, was 95.0% for gloves and 96.4% for polyester/cotton working coveralls during M&L, and 91.1% for gloves and 94.9% for non-certified coveralls during all application scenarios. This analysis confirms the essential role of PPE and non-certified working coveralls in reducing operator exposure to pesticides. Outliers indicate that operators need to be properly trained and adhere to label instructions to apply pesticides according to good agricultural practices.
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- 2024
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8. An IFNγ-dependent immune–endocrine circuit lowers blood glucose to potentiate the innate antiviral immune response
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Šestan, Marko, Mikašinović, Sanja, Benić, Ante, Wueest, Stephan, Dimitropoulos, Christoforos, Mladenić, Karlo, Krapić, Mia, Hiršl, Lea, Glantzspiegel, Yossef, Rasteiro, Ana, Aliseychik, Maria, Cekinović Grbeša, Đurđica, Turk Wensveen, Tamara, Babić, Marina, Gat-Viks, Irit, Veiga-Fernandes, Henrique, Konrad, Daniel, Wensveen, Felix M., and Polić, Bojan
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Viral infection makes us feel sick as the immune system alters systemic metabolism to better fight the pathogen. The extent of these changes is relative to the severity of disease. Whether blood glucose is subject to infection-induced modulation is mostly unknown. Here we show that strong, nonlethal infection restricts systemic glucose availability, which promotes the antiviral type I interferon (IFN-I) response. Following viral infection, we find that IFNγ produced by γδ T cells stimulates pancreatic β cells to increase glucose-induced insulin release. Subsequently, hyperinsulinemia lessens hepatic glucose output. Glucose restriction enhances IFN-I production by curtailing lactate-mediated inhibition of IRF3 and NF-κB signaling. Induced hyperglycemia constrained IFN-I production and increased mortality upon infection. Our findings identify glucose restriction as a physiological mechanism to bring the body into a heightened state of responsiveness to viral pathogens. This immune–endocrine circuit is disrupted in hyperglycemia, possibly explaining why patients with diabetes are more susceptible to viral infection.
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- 2024
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9. How much is just maths?Investigating problem solving in chemical kinetics at the interface of chemistry and mathematics through the development of an extended mathematical modelling cycle
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Ye, Sofie, Elmgren, Maja, Jacobsson, Magnus, and Ho, Felix M.
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Problem solving in chemical kinetics poses substantial challenges for university students since it often involves significant use of mathematics as a tool and language, with challenging translations and transitions between chemical phenomena and mathematical representations. In this paper, we present key findings from a study investigating chemistry students solving tasks centred around the steady-state approximation. Building upon the mathematical modelling cycle (MMC), qualitative analysis of the data collected using a think-aloud protocol led to the development of the extended MMC. This empirically derived extended MMC offers a more detailed account of the processes involved in mathematical modelling of chemical phenomena, highlighting aspects such as the occurrence of deliberation and evaluation throughout the modelling cycle, as well as the varying characteristics, points of activation and roles of extra-mathematical resources during problem solving. We further introduce and use problem-solving trajectories as a tool for visualising and analysing the complex and diverse approaches used by students in their attempts at reaching a solution. Overall, the extended MMC provides a finer-grained model of the cognitive and metacognitive activities that students engage in, offering further insights for research and practice.
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- 2024
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10. Municipal social expenditures and maternal health disparities: a study of linked birth and hospitalisation records
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Muchomba, Felix M, Teitler, Julien O, and Reichman, Nancy E
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BackgroundLocal government expenditures provide services and benefits that can affect health but the extent to which they are associated with narrowing or widening of racial/ethnic and socioeconomic disparities in health is unknown. We examined race/ethnicity-stratified and education-stratified associations between municipal social expenditures—those on housing, transportation, education, and other society-wide needs—and serious life-threatening maternal health conditions in a large US state.MethodsIn this cross-sectional study, we used individual birth records for 1 003 974 births in the state of New Jersey from 1 January 2008 to 31 December 2018 linked to individual maternal hospital discharge records and municipality-level characteristics for 564 municipalities. Severe maternal morbidity (SMM) was identified in the discharge records using a measure developed by the US Centers for Disease Control and Prevention. Associations between municipal-level social expenditures per capita and SMM were estimated using multilevel logistic models.ResultsResiding in a municipality with higher social expenditures was associated with lower odds of SMM across all racial/ethnic groups and education levels. Overall, 1% higher annual social expenditures per capita was associated with 0.21% (95% CI −0.29 to –0.13) lower odds of SMM. The associations were greater for individuals with less than a high school education than for those in the other educational groups in both relative (lnOR −0.53; 95% CI −0.74 to –0.31) and absolute (β −0.013; 95% CI −0.019 to –0.008) terms.ConclusionMunicipal-level spending on social services is associated with narrowing socioeconomic disparities in SMM. Narrowing racial/ethnic disparities in maternal health will likely require intervening beyond the provision of services to addressing historical and ongoing structural factors.
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- 2024
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11. Notfälle in der Augenheilkunde: Vermittlung anhand interaktiver Key-feature-Fälle für Medizinstudierende
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Müller, Andreas, Wagner, Felix M., Schuster, Alexander K., Günal, Betül, Pfeiffer, Norbert, Schmidt, Franziska, and Prokosch, Verena
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Hintergrund: Wichtiges Ziel eines Curriculums für Medizinstudierende ist, die Fähigkeit zum selbstständigen Erkennen und Einordnen von Notfällen zu vermitteln. Die Augenheilkunde steht hierbei aufgrund fachspezifischer „red flags“, also Warnsymptomen und -zeichen, vor der Herausforderung, dass solche selten von anderen Organsystemen hierauf übertragen werden können. Um Medizinstudierende dabei zu fördern, die „red flags“ der Augenheilkunde in ihrer späteren Tätigkeit zu erkennen, entwickelten wir für unser eLearning-Angebot leitsymptomorientierte interaktive Fallvignetten. Material und Methoden: Es wurden 7 interaktive Fallvignetten zu potenziell bedrohlichen ophthalmologischen Symptomen und Zeichen wie „schmerzloser Visusverlust“ oder „rotes Auge“ entwickelt. Hierbei werden Studierende mit Bild und Text durch einen Fall geführt und zu entscheidenden Aspekten („key features“) mit verschiedenen Frageformaten geprüft. Die interaktiven Fälle wurden mithilfe von eLearning-Authoring-Software umgesetzt und als Lernmodule in der Learning-Management-Präsenz der Augenklinik integriert. Die Patientenfälle waren Teil unseres Praktikums der Augenheilkunde. Die Fälle wurden im Anschluss von den Studierenden evaluiert. Ergebnisse: Die Fälle wurden im Mittel mit einer Note von 1,51 ± 0,68 (Mittelwert ± Standardabweichung) bewertet (n= 163). Auf einer Likert-Skala wurden sie mit 1,60 ± 0,81 als hilfreich für das eigene Lernen empfunden (1 = sehr hilfreich, 7 = gar nicht hilfreich; n= 164). Die Informationsmenge und Auswahl der Szenarien wurden ebenfalls positiv evaluiert. Diskussion: Um Studierenden im engen zeitlichen Rahmen eines Kurses mehr Sicherheit im Erkennen und der primären Versorgung von augenärztlichen Notfällen verschaffen zu können, können praxisorientierte Key-feature-Fälle Bestandteil eines eLearning-Angebotes sein.
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- 2024
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12. Clinical Applications of Radiomics in Nuclear Medicine
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Lohmann, Philipp, Bundschuh, Ralph Alexander, Miederer, Isabelle, Mottaghy, Felix M., Langen, Karl Josef, and Galldiks, Norbert
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- 2023
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13. Validation of Dual-Action Chemo-Radio-Labeled Nanocarriers with High Efficacy against Triple-Negative Breast Cancer
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Ilyas, Shaista, E. M. Sahnoun, Sabri, Szymura, Annika, Pes, Jonas, Habib, Shahin, Florea, Alexandru, Schäfer, Laura, Buhl, Eva Miriam, Morgenroth, Agnieszka, Habib, Pardes, Mottaghy, Felix M., and Mathur, Sanjay
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Identification and selectivity of molecular targets with prolonged action for difficult-to-target cancer such as triple-negative breast cancer (TNBC) represent a persisting challenge in the precision delivery of therapeutics. In the quest to target undruggable sites, this study validates the bioavailability of polydopamine-sealed mesoporous silica nanocarriers (PDA-mSiO2) for in vivo drug delivery to TNBC. For controlled transport and release, the chemotherapeutic drug doxorubicin was encapsulated in mSiO2nanocarriers coated with a PDA layer serving as a stimuli-responsive gatekeeper or seal. For unifying targeting and treatment modalities, these nanocarriers were covalently conjugated to a macrocyclic chelator (DOTA) and folate (FA-mSiO2.) that enabled incorporation of radionuclides and identification of FR Alpha (FolRα) receptors present on TNBC cells. The robust chemical design of FA- and DOTA-functionalized PDA-coated mSiO2nanocarriers constitutes mild reaction conditions to avoid the loss of surface-bound molecules. The radiolabeling studies with the theranostic pair 68Ga and 177Lu showed quantitative trends for radiochemical efficacy and purity. Nanocarriers equipped with both radiolabels and affinity ligands were optimally stable when incubated with human serum for up to 120 h (177Lu), demonstrating hydrophilicity with a partition coefficient (log P) of −3.29 ± 0.08. Specifically, when incubated with TNBC cells, the cells received significant FA-mSiO2carriers, demonstrating efficient carrier internalization and time-dependent uptake. Moreover, in vivo results visualize the retention of drug-filled carriers at the tumor sites for a long time, which holds promise for therapeutic studies. This research work demonstrates for the first time the successful dual conjugation of nanocarriers through the colocation of radionuclides and anticancer drugs that is promising for both live molecular imaging and enhanced therapeutic effect for TNBC.
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- 2023
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14. Optically heralded microwave photon addition
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Jiang, Wentao, Mayor, Felix M., Malik, Sultan, Van Laer, Raphaël, McKenna, Timothy P., Patel, Rishi N., Witmer, Jeremy D., and Safavi-Naeini, Amir H.
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Photons with optical frequencies of a few hundred terahertz are perhaps the only way to distribute quantum information over long distances. Superconducting qubits, which are one of the most promising approaches for realizing large-scale quantum machines, operate on microwave photons at frequencies that are ~40,000 times lower. To network these quantum machines across appreciable distances, we must bridge this frequency gap. Here we implement and demonstrate a transducer that can generate correlated optical and microwave photons. We use it to show that by detecting an optical photon we generate an added microwave photon with an efficiency of ~35%. Our device uses a gigahertz nanomechanical resonance as an intermediary, which efficiently couples to optical and microwave channels through strong optomechanical and piezoelectric interactions. We show continuous operation of the transducer with 5% frequency conversion efficiency, input-referred added noise of ~100, and pulsed microwave photon generation at a heralding rate of 15 Hz. Optical absorption in the device generates thermal noise of less than two microwave photons. Improvements of the system efficiencies and device performance are necessary to realize a high rate of entanglement generation between distant microwave-frequency quantum nodes, but these enhancements are within reach.
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- 2023
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15. Enzymatic Halogenation of Terminal Alkynes
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Lukowski, April L., Hubert, Felix M., Ngo, Thuan-Ethan, Avalon, Nicole E., Gerwick, William H., and Moore, Bradley S.
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The biosynthetic installation of halogen atoms is largely performed by oxidative halogenases that target a wide array of electron-rich substrates, including aromatic compounds and conjugated systems. Halogenated alkyne-containing molecules are known to occur in Nature; however, halogen atom installation on the terminus of an alkyne has not been demonstrated in enzyme catalysis. Herein, we report the discovery and characterization of an alkynyl halogenase in natural product biosynthesis. We show that the flavin-dependent halogenase from the jamaicamide biosynthetic pathway, JamD, is not only capable of terminal alkyne halogenation on a late-stage intermediate en route to the final natural product but also has broad substrate tolerance for simple to complex alkynes. Furthermore, JamD is specific for terminal alkynes over other electron-rich aromatic substrates and belongs to a newly identified family of halogenases from marine cyanobacteria, indicating its potential as a chemoselective biocatalyst for the formation of haloalkynes.
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- 2023
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16. Neural Stem Cells as Carriers of Nucleoside-Conjugated Nanogels: A New Approach toward Cell-Mediated Delivery
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Morgenroth, Agnieszka, Baazaoui, Fatima, Hosseinnejad, Aisa, Schäfer, Laura, Vogg, Andreas, Singh, Smriti, and Mottaghy, Felix M.
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Neural stem cells (NSCs) present attractive natural drug delivery systems (DDSs). Their migratory potential enables crossing of the blood–brain barrier and efficient and selective accumulation near malignant cells. Here, we present the potential of NSCs as DDSs for nucleoside analogue-conjugated nanogels (NGs). Two different approaches were investigated: the intracellular loading and extracellular cell surface decoration with NGs. For both designs, the tumor-specific migratory potentials of NSCs remained unchanged; however, the intracellular loading showed a shorter NG retention. The cell surface decoration protocol yielded a high loading capacity of 100% after 1 h and a prolonged drug retention. A redox-sensitive linker between NGs and the nucleoside analogue 5-ethynyl-2′-deoxycytidine (EdC) allowed a tumor environment-specific drug release and its efficient and preferential incorporation into the DNA of the tumor cells. Interestingly, the tumor-trafficking potentials of NSCs were significantly potentiated by irradiation of tumor cells. In conclusion, this study indicates the potentials of cell surface-decorated NSCs as DDSs for tumor-specific release, cellular uptake, and incorporation of EdC into DNA.
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- 2023
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17. Transparent Exploration of Machine Learning for Biomarker Discovery from Proteomics and Omics Data
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Torun, Furkan M., Virreira Winter, Sebastian, Doll, Sophia, Riese, Felix M., Vorobyev, Artem, Mueller-Reif, Johannes B., Geyer, Philipp E., and Strauss, Maximilian T.
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Biomarkers are of central importance for assessing the health state and to guide medical interventions and their efficacy; still, they are lacking for most diseases. Mass spectrometry (MS)-based proteomics is a powerful technology for biomarker discovery but requires sophisticated bioinformatics to identify robust patterns. Machine learning (ML) has become a promising tool for this purpose. However, it is sometimes applied in an opaque manner and generally requires specialized knowledge. To enable easy access to ML for biomarker discovery without any programming or bioinformatics skills, we developed “OmicLearn” (http://OmicLearn.org), an open-source browser-based ML tool using the latest advances in the Python ML ecosystem. Data matrices from omics experiments are easily uploaded to an online or a locally installed web server. OmicLearn enables rapid exploration of the suitability of various ML algorithms for the experimental data sets. It fosters open science via transparent assessment of state-of-the-art algorithms in a standardized format for proteomics and other omics sciences.
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- 2023
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18. Protection by ordinary light clothing against pesticide spray drift for bystanders and residents
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Felkers, Edgars, Kuster, Christian J., Adham, Sarah, Hewitt, Nicola J., and Kluxen, Felix M.
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There are stringent EU regulatory requirements to assess pesticide exposure to bystanders and residents to direct spray drift. A “light clothing” adjustment factor (AF) of 0.82 is applied in the exposure assessment, based on simple assumptions for covered body surface and penetration through clothing. To assess the appropriateness of the AF, we collated data from 32 field studies. The mean and 25th percentile % reduction from ordinary light clothing (“reduction %”) in children and adults for all crops and standard and drift-reducing nozzles were 42.7% and 36.2%, resulting in AF of 0.573 and 0.638, respectively. Sources of variation were investigated, e.g. crop type, leaf coverage, buffer, spray pressure, and nozzle type, which indicated that reduction % could be impacted by several conditions. The reduction % is similar between crops; therefore, a single AF value covering all crops can be derived. One exception was for early-stage vineyard scenarios (the reduction % is lower (27%) than late stage (42–47%)) and could be considered individually to avoid unnecessary conservatism for the other scenarios. This evaluation demonstrates the current AF to be overly precautionary, and a more realistic, exposure scenario-relevant value could be applied for bystander/resident risk assessments.
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- 2023
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19. Looking for solutions: students’ use of infrared cameras in calorimetry labs
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Samuelsson, Christopher Robin, Ho, Felix M., Elmgren, Maja, and Haglund, Jesper
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This study adds to the growing body of research on laboratory work. The study involves four pairs of students in a university introductory calorimetry lab of which two pairs, the IR-pairs (infrared camera-pairs), were given access to infrared cameras to use however they liked during their course lab work. Two other pairs, the T-pairs (thermometer-pairs), were not given access to infrared cameras during their course lab work. The IR-pairs were video recorded when they chose to use the IR cameras and the T-pairs were video-recorded during the corresponding sequences. Additionally, all pairs participated in a modified lab after their course lab, in which the pairs had access to IR cameras and were presented with the same phenomena although with equipment modified to better accommodate for the use of IR cameras (thin plastic cups were used instead of calorimeters). Students’ practice, communication and reasoning was studied to explore how the IR cameras affect students’ activity. The results show that the access to IR cameras led to a reasoning focused on a macroscopic level of chemistry knowledge, involving heat transfer to the surrounding and measurement errors, and that the lab practice of most of the students was continuous (rather than intermittent) when they had access to IR cameras. We conclude by arguing that the access to IR cameras affects students’ conceptual and epistemological framing of the lab, i.e.that the students perceive the lab activity differently when they get access to IR cameras (both in a conceptual and epistemological sense). As an implication for teaching, we suggest that giving students access to IR cameras in a chemistry lab may be a way to introduce flexibility in the degree of openness of the lab.
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- 2023
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20. Biomechanical inverted pendulum: a model for initial testing of interaction controls
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Mosconi, Denis, Escalante, Felix M., Terra, Marco H., and Siqueira, Adriano Almeida G.
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Computational models of the neuromusculoskeletal system are useful for developing controls applied to rehabilitation robots. However, due to the high non-linearity, number of states and degrees of freedom, some models require a reasonable computational cost, making the development of controls slow, specially in the first stages. In this work we proposed the biomechanical inverted pendulum: a computational model of an inverted pendulum actuated by a set of four muscle-tendon and one linear coordinate actuator, presenting nonlinearities in both the mechanical and biomechanical parts, covering the problem of muscle redundancy and being less complex than a neuromusculoskeletal one. Such a model is expected to be useful for the development and testing of human-robot interaction controls in the first stage of the project. Two simulations with the proposed pendulum were performed: swing up and tracking movements. The results obtained with these two simulations proved that the biomechanical inverted pendulum is a feasible and useful model for the first tests with controls applied to biomechanical systems, allowing fast simulations and producing coherent results.
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- 2023
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21. Chronic lymphocytic leukemia presence impairs antigen-specific CD8+T-cell responses through epigenetic reprogramming towards short-lived effectors
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Martens, Anne W. J., Kavazović, Inga, Krapić, Mia, Pack, Su Min, Arens, Ramon, Jongejan, Aldo, Moerland, Perry D., Eldering, Eric, van der Windt, Gerritje J. W., Wensveen, Felix M., Peters, Fleur S., and Kater, Arnon P.
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T-cell dysregulation in chronic lymphocytic leukemia (CLL) associates with low response rates to autologous T cell-based therapies. How CLL affects antigen-specific T-cell responses remains largely unknown. We investigated (epi)genetic and functional consequences of antigen-specific T-cell responses in presence of CLL in vitro and in an adoptive-transfer murine model. Already at steady-state, antigen-experienced patient-derived T cells were skewed towards short-lived effector cells (SLEC) at the expense of memory-precursor effector cells (MPEC). Stimulation of these T cells in vitro showed rapid induction of effector genes and suppression of key memory transcription factors only in presence of CLL cells, indicating epigenetic regulation. This was investigated in vivo by following antigen-specific responses of naïve OT-I CD8+cells to mCMV-OVA in presence/absence of TCL1 B-cell leukemia. Presence of leukemia resulted in increased SLEC formation, with disturbed inflammatory cytokine production. Chromatin and transcriptome profiling revealed strong epigenetic modifications, leading to activation of an effector and silencing of a memory profile through presence of CLL cells. Secondary challenge in vivo confirmed dysfunctional memory responses by antigen-experienced OT-I cells generated in presence of CLL. Altogether, we show that presence of CLL induces a short-lived effector phenotype and impaired memory responses by epigenetic reprogramming during primary responses.
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- 2023
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22. Intraoperative pneumatic tourniquet application reduces soft-tissue microcirculation, but without affecting wound healing in calcaneal fractures
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Lichte, Philipp, Bläsius, Felix M., Ganse, Bergita, Gueorguiev, Boyko, Pastor, Torsten, Nebelung, Sven, Migliorini, Filippo, Klos, Kajetan, Modabber, Ali, Scaglioni, Mario F., Schopper, Clemens, Hildebrand, Frank, and Knobe, Matthias
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Background: Wound healing complications are a major challenge following the extended lateral approach in calcaneal fractures. Soft-tissue microcirculation plays an important role via the delivery of oxygen, nutrients, and the regulation of a local milieu. The aim of this clinical study was to examine the effect of intraoperative pneumatic tourniquet application on skin and subcutaneous microcirculation, and its impact on wound healing progression. Methods: Patients with calcaneal fractures were randomly assigned to two groups defined by a surgery conducted either with use or without use of a tourniquet. Blood flow (BF [AU]), tissue oxygen saturation (SO
2 [%]) and the relative amount of haemoglobin (rHb[AU]) were intraoperatively measured at two depths (2 and 8 mm) non-invasively by spectrophotometry (Micro-Lightguide O2C® , LEA Medizintechnik, Giessen, Germany).Time points were before and after inflation of the pneumatic tourniquet and also at the end of surgery before deflation. A linear mixed model (LMM) was fitted for statistical analysis. Results: Thirty-four patients (3 women and 31 men) with 37 calcaneal fractures were included. In 22 of them, the surgery was conducted with a tourniquet and in the other 15 without its use. A significant decrease of microcirculation, characterized by decreases in blood flow (p = 0.011) and tissue oxygenation (p = 0.023) was measured in 8 mm depth after inflating the tourniquet. However, these changes did not influence the time of postoperative wound healing. Conclusion: The use of a pneumatic tourniquet reduces deep microcirculation without affecting postoperative wound healing.- Published
- 2024
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23. PULMONARY CAVITARY LESIONS IN THE CONTEXT OF ANCA-POSITIVE VASCULITIS: A CLINICAL REPORT
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TAVAREZ, CRISTY and REYES, FELIX M
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- 2024
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24. TEZEPELUMAB-EKKO IN ELDERLY ASTHMATICS: A CASE SERIES REVEALING REAL-WORLD INSIGHTS
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TAVAREZ, CRISTY, CHUKWUDUM, CHIDINMA, and REYES, FELIX M
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- 2024
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25. Uneasy Bedfellows: AI in the News, Platform Companies and the Issue of Journalistic Autonomy
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Simon, Felix M.
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AbstractPlatform companies play an important role in the production and distribution of news. This article analyses this role and questions of control, dependence and autonomy in the light of the ‘AI goldrush’ in the news. I argue that the introduction of AI in the news risks shifting even more control to and increasing the news industry’s dependence on platform companies. While platform companies’ power over news organisations has to date mainly flown from their control over the channels of distribution, AI potentially allows them to extend this control to the means of production as the technology increasingly permeates all stages of the news-making process. As a result, news organisations risk becoming even more tethered to platform companies in the long-run, potentially limiting their autonomy and, by extension, contributing to a restructuring of the public arena as news organisations are re-shaped according to the logics of platform businesses. I conclude by mapping a research agenda that highlights potential implications and spells out areas in need of further exploration.
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- 2022
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26. Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a pragmatic, cluster-randomised trial in seven low-income and middle-income countries
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Andoh, Aaron B, Atindaana Francis, Abantanga, Abdulkarim, Abdulhafiz A, Adesunkanmi, Abdulhafiz O, Salako, Abdulkadir A, Soladoye, Abdulmajeed, Sheshe, Abdulrahman A, Sani, Abdulrasheed, Lawal, Abdulrazzaq O, Lawal, Abdulwahab, Tripathi, Abhilasha, S, Abhishek, Akinloye, Abidemi, Olajumoke Balogun, Abigail, Ariyibi, Abimbola L, Okunlola, Abiodun I, Ojewuyi, Abiodun R, Oyedele, Abisola E, Sakyi, Abraham, Oladimeji, Abraham T, Bala Muhammad, Abubakar, Yahaya, Abubakar, Soibi-Harry, Adaiah P, Gyambibi, Addo K, Adeniyi, Adebayo A, Adeoluwa, Adebunmi, Olumide Osinowo, Adedapo, Salawu, Adedayo I, Fatuga, Adedeji L, Adesiyakan, Adedotun, Fakoya, Adegbolahan, Naah, Adeline, Adeyeye, Ademola A, Talabi, Ademola O, Fasanu, Adeniyi O, Ayoola Orowale, Adeola, Ojajuni, Adeolu, Adelaja, Aderinsola T, Ademuyiwa, Adesoji O, Jimoh, Adesola I, Aderounmu, Adewale A, Adisa, Adewale O, Ajagbe, Adewale O, Olajide, Adewale T, Bakare, Adewumi, Okunowo, Adeyemi A, Tchogo, Affisatou, Koledade, Afolabi K, Barthelemy Yevide, Agossou, Bello, Ahmad, Shehu Umar, Ahmad, Lawal, Ahmad T, Obiesie, Ahuizechukwu E, Dieudonne Hirwa, Aime, Domingo, Aimee, Mustapha, Aisha, Abdullahi, Aisha, Hada, Aissatou, Ijeoma, Aja, Adeleke, Akeem A, Adepiti, Akinfolarin C, Ajao, Akinlabi E, Sanusi, Akinsola T, Houndji, Albert, Bernal Hernández, Aldo, González Ojeda, Alejandro, Serrano García, Alejandro G, Ohemu, Alexander A, Arekhandia, Alexander I, Yakubu, Alfa, Hepzibah, Alice, Bhatt, Alisha, Muhammad Tukur, Aliyu, Ingabire, Allen JC, Okechukwu Ugwu, Aloy, Karekezi, Aloys, Maalekuu, Aloysius, Imanishimwe, Alphonsine, Bruce-Adjei, Amanda, Obbeng, Ambe, Akosua, Ameley, Jeffery-Felix, Ametepe, Mohammed-Durosinlorun, Amina A, Jimoh, Aminat O, Umar, Aminatu M, Umar, Aminu M, Mahajan, Amit, Eziyi, Amogu K, Bennin, Amos, Dasari, Amos, Okedare, Amos, Mathew, Amy E, Florencia Casado-Zarate, Ana, Calderón-Alvarado, Ana B, Dominguez, Ana Camille G, Cortés Flores, Ana O, Dusabimana, Anaclet, Kutma, Ananta, Byaruhanga, Anastase, Houndote, Anasthasie, Cueto Valadez, Andrea E, Alvarez Villaseñor, Andrea S, Bhangu, Aneel, Ortega Barreiro, Angelica, Mortola Lomeli, Angelo Fernando, Luther, Anil, Yahya, Anisah, Eseenam Agbeko, Anita, Thomas, Anita, Goyal, Ankush, Mkoh Dikao, Anne Stredy, Appiah, Anthony Baffour, Gaou, Antoine, Bediako-Bowan, Antoinette A, Ramos De la Medina, Antonio, Seidu, Anwar S, Munyaneza, Aphrodis, Ahounou, Aristide, Akoto-Ampaw, Arko, Hadonou, Armel, Alitonou, Arnaud, Sambo, Arouna, Mathew, Arpit J, Chaturvedi, Arun, Gautham, Arun K, Choudhrie, Ashish Victor, Attri, Ashok K, Kumar, Ashwani, Sukumar, Ashwin, Mehraj, Asif, Shittu, Asimiyu, Mukasine, Athanasie, Oppon-Acquah, Ato, Kusiwaa, Atta, Suroy, Atul, Ezenwa, Augusta O, Takure, Augustine O, Akinniyi, Ayodeji, Ogunyemi, Ayokunle A, Makanjuola, Ayomide, Dossou Yovo, B.T. Bonheur, Alhassan, Baba A B, Hamza, Babatunde K, Awoyinka, Babatunde S, Koomson, Barbara, Aminu, Bashiru, Abodunde Muideen, Bello, Osunwusi, Benedetto, García Reyna, Benjamín, Oppong, Benjamin A, Brimpong, Benjamin B, Fenu, Benjamin S, Ofori, Bernard A, Guzmán Ramírez, Bertha G, Nyadu, Bertina B, Shankar, Bharat, Lawal, Bilkisu K, Armstrong Alia, Bill, Roy, Bipradas, Kontor, Bismark E, Kovohouande, Blaise, Cakpo, Boniface, Enriquez Barajas, Brenda Vanessa, Crocco Quiros, Bruno, Kadir, Bryar, Mohammed, Caleb, Nwachukwu, Calistus U, Colunga Tinajero, Carlos, Ruiz Velasco, Carlos B, Zuloaga Fernández del Valle, Carlos J, Noufuentes, Carmen, Solomi, Carolin V, Okunlola, Cecilia K, Seneza, Celestin, Okafor, Celestine I, Nuño Escobar, Cesar, Banka, Charles, Barimah, Charles G, Chetana, Chetana, Nyatsambo, Chido, Okeke, Chike J, Jeffrey Ede, Chikwendu, Nwosu, Chimdiebele Daisy, Victoria Mgbemena, Chinelo, Onyeka, Chinonso U, Gold, Chinta S, Faith Uche, Chisom, Chigoze Makwe, Christian, Urimubabo, Christian Jean, Coompson, Christian L, Ashley-Osuzoka, Christiana, Gbenga-Oke, Christianah, Bidemi Oyegbola, Christianah, Mukakomite, Christine, Mpirimbanyi, Christophe, Asare, Christopher, Bode, Christopher O, Ugwunne, Chuka, Onyejiaka, Chukwudubem C, Okoro, Chukwuemeka, Okereke, Chukwuma E, Mukangabo, Clemence, Sie-Broni, Clement, Ballu, Cletus, Fuentes Orozco, Clotilde, Kyeremeh, Collins, Adumah, Collins C, Ruelas Bravo, Cornelio, Bokossa Kandokponou, Covalic Melic, Guerrero Ramírez, Cristhian S, Teye-Topey, Cynthia, Kpangon, Cyrille, Chinyio, Damai, Orozco Ramirez, Damaris, Mora Santana, Damián, Nyirasebura, Dancilla, Hérnandez Alva, Daniel A, Acquah, Daniel K, Prakash, Danita D, Sale, Danjuma, Olulana, Dare Isaac, Oruade, David, Jayne, David, Morales Iriarte, David Giovanny I, Ogudi, David K D, Olatola, David O, Akinboyewa, David O, Irabor, David O, Nuwam, Deborah, Mukantibaziyaremye, Deborah, Jain, Deepak, Singla, Deepak, Garnaik, Deepak K, Singh, Deepak S, Gakpetor, Delali A, Esssien, Derick, Rubanguka, Desire, Poonia, Dharma R, Ghosh, Dhruva, Ahogni, Didier, Morton, Dion, Umuhoza, Divine, Morel Seto, Djifid, Nepogodiev, Dmitri, Enti, Donald, Smith, Donna, Osei-Poku, Dorcas, Acheampong, Dorcas O, Mellado, Dorihela H, Ofosuhene, Doris, Cortes Torres, Edgar J, Efren Lozada, Edgard, Gómez Sánchez, Eduardo, González Espinoza, Eduardo, Osei, Edwin, Mensah, Elijah, Rwagahirima, Elisee, Quartson, Elizabert M, Li, Elizabeth, Kurien, Elizabeth N, Bonilla Ahumada, Elyoenai, Kabanda, Elysee, Odame, Emelia, Izabiriza, Emelyne, Hatangimana, Emery, Osariemen, Emili, Reyes Elizalde, Emilio A, Agbowada, Emma A, Usam, Emmanuel, Sylvester Inyang, Emmanuel, Owie, Emmanuel, Ojo Williams, Emmanuel, Munyaneza, Emmanuel, Mutabazi, Emmanuel, Kojo Acquah, Emmanuel, Obiri, Emmanuel L, Ofori, Emmanuel O, Runigamugabo, Emmy, Yhoshu, Enono, Malade, Enrif, Cervantes Perez, Enrique, Kobby, Ephraim, Okwudiri Ohazurike, Ephraim, Jerry Bara, Eric, Agyemang, Eric, Akoto, Erica, Villanueva-Martínez, Erick E, Mwungura, Espoir, Cueva Martinez, Esteban, Asabre, Esther, Adjei-Acquah, Esther, Abunimye, Esther, Daluk, Esther B, Daniel, Esther R, Ike Okorie, Ethos, Ailunia, Eunice E, Abraham, Eunice S, Romo Ascencio, Evelia V, Harrison, Ewen, Kpatchassou, Expedit, Bakari, Fadimatu, González Ponce, Fanny Y, Huda, Farhanul, Abubakari, Fatao, Ntirenganya, Faustin, Ingabire, Faustine, Parray, Fazl Q, Brant, Felicity, Alakaloko, Felix M, Diaz Samano, Fernanda, Duque Zepeda, Fernando, Bello-Tukur, Firdaws, Basirwa Musengo, Fiston, Dedey, Florence, Adegoke, Folasade, Amponsah-Manu, Forster, Mukaneza, Francine, Chinonso Ezenwankwo, Francis, Sanwo, Francis, Dossou, Francis Moise, Nwaenyi, Francisca C, Ibanez Ortiz, Francisco, Barbosa Camacho, Francisco J, León-Frutos, Francisco J, Plascencia Posada, Francisco J, Nirere, Francoise, Owusu, Frank, Gyamfi, Frank E, Wuraola, Funmilola O, Cervantes Guevara, Gabino, Ntwari, Gabriel, Ambriz-González, Gabriela, Hyman, Gabriella, Umar, Garzali I, Thami, Gaurav, Adeleye, Gbadebo T C, Limann, Gbana, Ajibola, Gboyega, Ida, Genesis, Ihediwa, George C, Brown, George D, Bucyibaruta, Georges, Gallardo Banuelos, Gerardo, Lopez Arroyo, Gerardo, Ndegamiye, Gibert, Naah, Gifty, Morgan Villela, Gilberto, Edet, Glory, Attepor, Godsway S, Akaba, Godwin O, Aziz, Gowhar, Yeboah, Grace, Mary, Grace, Eke, Grace, Castillo Cardiel, Guadalupe, Yanowsky Reyes, Guillermo, Sanchez Villaseñor, Guillermo, Cervantes Cardona, Guillermo A, Singh, Gurtaj, Boateng, Guy C, Kola, H.Pauline, Abdullahi, Habiba I, Olaide Raji, Hadijat, Ahmed, Hafsa I, Umaru-Sule, Hajara, Kaur, Harmanjot, Malechi, Hawa, Sunday, Helen, Abiyere, Henry O, Butana, Herbert, Agossou, Hermann, Samkelisiwe Nxumalo, Hlengiwe, Maniraguha, Hope Lydia, Dewamon, Hubert, Yome, Hugues, Behanzin, Hulrich, Ekwuazi, Hyginus O, Oweredaba, Ibiene T, Mohammed, Ibrahim, Sufyan, Ibrahim, Saidu, Ibrahim A, Abdul-Aziz, Iddrisu I A, Eseile, Ideyonbe Samuel, Ogolekwu, Idoko P, Adebara, Idowu O, Usman Takai, Idris, Fidelis Okafor, Ifeanyi, Kene, Ifeanyi A, Enyinnaya Iweha, Ikechukwu, Mutimamwiza, Immaculee, Mantoo, Imtiyaz, Duruewuru, Innocent O, Akpo, Irene, Niyongombwa, Irenee, Brancaccio Pérez, Irma V, Esparza Estrada, Isaac, Gundu, Isaac, Morkor Opandoh, Isabella N, Ncogoza, Isaie, Sibomana, Isaie, Bansal, Ishan, Cabrera-Lozano, Ishtar, Ishola Aremu, Isiaka, Gandaho, Isidore, Lawani, Ismail, Ochoa Rodríguez, Itzel, Alasi, Iyabo O, Alhassan, Jaabir, Mends-Odro, Jacqueline, Osuna Rubio, Jacqueline, Orozco Perez, Jaime, González Bojorquez, Jaime L, Rodriguez Ramirez, Jairo Arturo, Glasbey, James, Emeka, James J, Lawal, Jamila, Acquaye, Jane, Alfred, Janet, Rugendabanga, Janvier, Mizero, Japhet, Ingabire, JC Allen, Aimable Habiyakare, Jean, Claude Uwimana, Jean, de Dieu Haragirimana, Jean, Yves Shyirakera, Jean, Utumatwishima, Jean N, Niyomuremyi, Jean Paul, Majyabere, Jean Paul, Masengesho, Jean Pierre, Nyirahabimana, Jeannette, Vishnoi, Jeevan R, Kalyanapu, Jeffery A, Joseph, Jeremiah N, Makama, Jerry G, Pizarro Lozano, Jesus, Aguilar Mata, Jesus Antonion, Morales, Jesus Flavio M, Vega Gastelum, Jesus O, Oyekunle Bello, Jibril, Okechukwu Ugwu, Jideofor, Amoako, Joachim K, Simoes, Joana, Zirikana, Job, Nzuwa Nsilu, Joel, Adze, Joel A, Enaholo, Joel E, Obateru, John A, Chinda, John Y, Akunyam, Johnson, Boakye-Yiadom, Jonathan, Cook, Jonathan, Quansah, Jonathan I K, Chejfec Ciociano, Jonathan M, Jiménez Tornero, Jorge, Herrera-Esquivel, Jose, Flores Cardoza, Jose A, Sánchez Martínez, José A, Guzmán Barba, José A, Pesquera, Jose Alberto A, Orozco Navarro, Jose Esteban, Sandoval Pulido, José I, Pérez Navarro, Jose V, Igiraneza, Joselyne, Ejimogu, Joseph, Awindaogo, Joseph K, Ugboajah, Joseph O, Ashong, Josephine, Nsaful, Josephine, Arthur, Joshua, Yakubu, Josiah, Mutuyimana, Josiane, Umuhoza, Josine, Thomas, Josy, Ibarrola Peña, Juan C, Tijerina Ávila, Juan J, Oladayo Kuku, Jubril, Gyamfi, Jude E, Brown, Julia, Appiah, Juliana, Attinon, Julien, Jacob, Jurgen, Gimba, Justina, Seyi-Olajide, Justina O, Ngaguene, Juvenal, Jyoti, Jyoti, Leshiini, K, Boukari, K. Alassan, Kumar, Karan, Mumuni, Kareem, Quarchey, Karen N D, Sanni, Katia, Bozada-Gutierrez, Katya, Mandrelle, Kavita, Atobatele, Kazeem M, Awodele, Kehinde, Bawa, Kehinde G, Duromola, Kehinde Michael, Egbuchulem, Kelvin I, Ngaaso, Kennedy, Onyekachi, Kenneth, Ugwuanyi, Kenneth, Okoduwa, Kester O, Ado, Khadija A, Rathod, Kirti K, Nunoo-Ghartey, Kojo, Rautela, Komal, Kennedy, Korankye K, Ascencio Díaz, Kriscia V, Boakye-Yiadom, Kwaku, Onahi Iji, Lambert, Magill, Laura, Martinez Perez Maldonado, Laura, Pena Baolboa, Laura Gabriela, Montano Angeles, Laura Olivia, Barau Abdullahi, Lawal, Ismail, Lawani, Awere-Kyere, Lawrence K B, Uzikwambara, Leoncie, Adam-Zakariah, Leslie, Larbi-Siaw, Linda A, Chukwuemeka Anyanwu, Lofty-John, Etchisse, Lolyta, Abdulrasheed, Lubabatu, Agbanda, Lucien, García González, Luis A, Suárez Carreón, Luis O, Cifuentes Andrade, Luis R, Pacheco Vallejo, Luis R, Ramirez Gonzalez, Luis R, Aniakwo, Luke A, Olajide Abdur-Rahman, Lukman, Abdur-Rahman, Lukman Olajide, Namur, Luz del Carmen M, Mukamazera, Lydia, Airede, Lydia R, Nontonwanou, M.J. Bienvenue, Amoako-Boateng, Mabel P, Rodha, Mahaveer S, Kawu Magashi, Mahmoud, Abubakar, Maimuna, Yigah, Makafui, Dayie, Makafui S C J K, Victorin Agbangla, Mamonde, Pathak, Manish, Aggarwal, Manisha, Lokavarapu, Manoj J, Talla Timo, Manuella, Isikhuemen, Maradona E, Gbassi, Marcel, Uwizeye, Marcel, Akpla, Marcelin, Adjei, Margarey N M, Picciochi, Maria, Chávez, Maria, Fourtounas, Maria, Quirarte Hernández, María A, Zarate Casas, Maria F, Gloriose Nabada, Marie, Kouroumta, Marie-Claire, De Cristo Gonzalez Calvillo, Marijose, Trejo-Avila, Mario, Guzmán Ruvalcaba, Mario J, Monahan, Mark, Jesudason, Mark R, Zume, Marshall, Totin, Martin, Djeto, Martin, Awe, Martin, Islas Torres, Martin, Morna, Martin T, Oluwadamilola Adebisi, Mary, Adams, Mary Augusta, Oluwatobi Busari, Maryam, Lazo Ramirez, Maryzela, Taingson, Mathew C, Ruhosha, Mathias, Dery, Mathias K, Batangana, Mediatrice, Mellado Tellez, Mel P, Vicencio Ramirez, Melissa L, Agyapong, Meshach M, Nortey, Michael, Amao, Michael, Bahrami-Hessari, Michael, Calderón Llamas, Miguel A, Calderon Vanegas, Miguel Antonio, Azanlerigu, Millicent, Becerra Moscoso, Mitzi R, Sethoana, Mmule Evelyn, Oludara, Mobolaji A, Moussa Alidou, Mohamed, Mohammad, Mohammad A, Bashir, Mohammed, Usman, Mohammed, Adnan, Mohammed, Alhassan, Mohammed S, Aliyu, Mohammed S, Singh, Mohit, Muhindo, Moise, Dusabeyezu, Moise, Kichu, Moloti, Castillo, Monica N, Gureh, Monika, Hans, Monika A, Hollo, Monsede, Hodonou, Montcho Adrien, Sivakumar, Moonish V, Edena, Morrison E, Abdulsalam, Moruf A, Adebisi Ogunjimi, Moses, Dusabe, Moses, Dokurugu, Moses A, Galadima, Moses C, Agbulu, Moses Vincent, Agbadebo, Mouhamed, Eunice, Moyosoluwa Eunice, Nosipho Mathe, Mpho, Moreno-Portillo, Mucio, Awaisu, Mudi, Daniyan, Muhammad, Duke George, Mukoro, Malik, Muneer A, Amadu, Munira, Pai, Murlidhar V, Adetola Tolani, Musliu, Abdullahi, Muzzammil, Moussa, Nabil, Guessou, Nafissatou Orou, Saqib, Najmus, Christian, Nana Ama, Essel, Nanabanyin, Tabuanu, Nancy O, Olagunju, Naomi, Sam, Napoleon Bellua, Akhtar, Naseem, Oyelowo, Nasir, Bisimwa Mitima, Nathan, Adewole, Nathaniel D, Sharma, Naveen, Anthea Nhlabathi, Ncamsile, Mbajiekwe, Ndubuisi, Mishra, Neha, Pundir, Neha, Winkles, Neil, Smart, Neil, Agboadoh, Nelson, Ndukwe, Ngozi O, Aperkor, Nicholas T, Adu-Aryee, Nii A, Chowdri, Nisar A, Singh, Nishu, Peters, Nitin J, Sharma, Nivedita, Agrawal, Nivesh, Syam, Niyah, Duru, Nnamdi Jonathan, Sentholang, Nnosa, Okoi, Nnyonno, Anyanwu, Noble, Rene Hounsou, Nounagnon, Aliyu, Nura U, Abiola Adeleke, Nurudeen, Egwuonwu, Ochonma A, Okoye, Odili A, Hyginus Ekwunife, Okechukwu, Olanrewaju, Olabisi, Osagie, Olabisi O, Adeyemo, Olabisi T, Oshodi, Olabode A, Olaolu Ogundoyin, Olakayode, Ogundoyin, Olakayode O, Babalola, Olakunle F, Olasehinde, Olalekan, Ajai, Olalekan T, Balogun, Olanrewaju S, Lawal, Olatunji O, Olayioye, Olawunmi, Sayomi, Olayinka, Samuel, Oliver, Mwenedata, Olivier, Oluwaseyi Bakare, Oludayo, Sowande, Oludayo A, Ojewuyi, Olufemi O, Omisanjo, Olufunmilade A, Akintunde, Olugbenga P, Abiola, Olukayode P, Abiola, Olukayode P, Akande, Olukemi, Elebute, Olumide A, Adewara, Olumide E, Ayankunle, Olumide M, Odesanya, Oluremi J, Alatise, Olusegun I, Ajenifuja, Olusegun K, Ogunsua, Oluseyi O, Banjo, Oluseyi O, Ojediran, Oluwabukade, Oladele, Oluwafemi O, Fatudimu, Oluwafemi S, Ajagbe, Oluwasanmi A, Idowu, Oluwasegun C, Ladipo-Ajayi, Oluwaseun A, Taiwo, Oluwaseun A, Olaleye, Oluwaseun H, Oluseye, Oluwaseun O, Ige, Oluwasuyi, Odutola, Oluwatomi R, Atoyebi, Oluwole A, Omar, Omar, Ayandipo, Omobolaji O, Omotola, Omolara, Faboya, Omolara M, Williams, Omolara M, Irowa, Omorodion O, Salami, Omotade S, Onu, Onyekachi A, Asafa, Opeyemi Q, Akinajo, Opeyemi Rebecca, Osemwegie, Osarenkhoe, Osagie, Osasumwen T, Olvera Flores, Oscar, Iribhogbe, Oseihie I, Aisuodionoe-Shadrach, Oseremen, Gbehade, Oswald, Ojo, Owolabi D, Olubayo, Oyetunde O, Prabhu, P S, Flores Becerril, Paola, Kumar, Pardeep, Yanto, Parfait, Mukherjee, Partho, Haque, Parvez D, Koggoh, Patience, Igwe, Patrick O, Trinity, Paul, Aderemi Adegoke, Paul, Wondoh, Paul, Domínguez Barradas, Paulina, Ogouyemi, Pencome, Boakye, Percy, Brocklehurst, Peter, Elemile, Peter, Egharevba, Peter A, Agbonrofo, Peter I, Okoro, Philemon E, Kumassah, Philemon K, Mensah, Philip, Munda, Philip, Mshelbwala, Philip M, Alexander, Philip V, Nyirangeri, Pierrine, Muroruhirwe, Piolette, Hardy, Pollyanna, Kwabena, Ponala W, Zechariah, Pradeep, Nayak, Pragyanmai, Dummala, Prashant, Singh, Prashant, Solanki, Pratik, Yeboah Owusu, Prince, Mary, Priya, Chowdhury, Priyanka, Luri, Prosper T, Pareek, Puneet, Prakash, Puneet, Kumari, Pushplatha, Lillywhite, Rachel, Moore, Rachel, Tinuola Afolabi, Rafiat, Williams, Rahul, Alpheus, Rahul A, Sharma, Rajeev, Seenivasagam, Rajkumar K, Vakil, Rakesh, Armah, Ralph, Samujh, Ram, Chaudhary, Ramkaran, John, Raphael E, Gunny, Rashmi Jacob, Wani, Rauf A, Verma, Raunak, Thind, Ravinder Singh, Dar, Rayees A, Eghonghon, Raymond A, Acquah, Regina, Rajappa, Reuben, Kpankpari, Richard, Ofosu-Akromah, Richard, Romaric Soton, Rish, Jain, Rita, Guinnou, Robert, Munyaneza, Robert, Mares País, Roberto, Delano-Alonso, Roberto, Miranda Ackerman, Roberto C, Bello, Robiat, Kour, Robindera, Guadalupe Cano Arias, Rocio Guadalupe, Uwayezu, Roda, Nájar Hinojosa, Rodrigo, Mittal, Rohin, Ranjan, Rohit, Goudou, Roland, Cethorth Fonseca, Roland Kevin, Hussey, Romeo, Tubasiime, Ronald, Dukuzimana, Rongin, Varghese, Rose, Boateng, Ruby A, Pswarayi, Rudo, Ojewola, Rufus W, Abdus-Salam, Rukiyat A, Abdus-Salam, Rukiyat A, Sarfo Kantanka, Ruth, Manu, Ruth, Abdul-Hafiz, Saba, Oyewale, Sabur, Yussif, Safia, Abolade Lawal, Saheed, Kanyarukiko, Salathiel, Abeku Yusuf, Salisu, Suleiman, Salisu, Tabara, Salome, Mbonimpaye, Salomee, Kanyesigye, Sam, Joshua, Samaila, Tamou, Sambo Bio, Gupta, Sameer, Muhammad, Saminu S, Abdulai, Samira, Olori, Samson, Mensah, Samuel, Asirifi, Samuel A, Sani, Samuel A, Ajekwu, Samuel C, Nwokocha, Samuel U, Quaicoo, Sandra, Tsatsu, Sandra E, Philips, Sanish, Gupta, Sanjay, Misra, Sanjeev, Kaur, Savleen, Omorogbe, Scott O, Eniola, Sefiu B, Kwarteng, Seidu M, Tobome, Semevo Romaric, Emmanuel Hedefoun, Sena, Adams, Shamsudeen M, Singh, Shanky, Duniya, Sharon A N, Yahaya, Shekira, Mohammed, Sheriff, Rajan, Shiv, Adekola Adebayo, Sikiru, Ibarra Camargo, Silvia A, Cousens, Simon, Hinvo, Simplice, Kapoor, Simran, Singh, Simrandeep, Nindopa, Sinama, Jacob, Smitha E, Laurberg, Soeren, Chakrabortee, Sohini, Chowdhury, Sona, Mathai, Sonia, Prasad, Soosan, Tchati, Sorekou Victoire, Habumuremyi, Sosthene, Habumuremyi, Sosthene, Hamadou, Souleymane, Lawani, Souliath, Veetil, Sreejith K, D, Sreekar, D, Sreekar, Sharma, Srujan, Doe, Stanley, Mathew, Stanley, Emeka Nwabuoku, Stanley, Ideh, Stanley N, Laurent Loupeda, Stephane, Tabiri, Stephen, Olutola, Stephen, Kache, Stephen A, Bature, Stephen B, Garba, Stephen E, Gana, Stephen G, Soni, Subhash C, Raul, Subrat, Kanchodu, Sudheer, Daneji, Sulaiman M, Sallau, Suleiman B, P T, Sundeep, Saluja, Sundeep S, Goyal, Sunita, Surendran, Suraj, Joseph, Susan, John, Suzan, Obiechina, Sylvester O, Hounsa, Sylvestre, Lawal, Taiwo A, Badmus, Tajudeen A, Bakare, Tajudeen I B, Mohammed, Tajudeen O, Cueto Valadez, Tania A, Dhar, Tapasya, Agida, Teddy E, Arkorful, Temitope E, Atim, Terkaa, Orewole, Tesleem O, Wordui, Theodore, Okonoboh, Theophilus O, Mavoha, Thierry, Hessou, Thierry K, Agyen, Thomas, Pinkney, Thomas, Olajide, Thomas O, Odunafolabi, Tunde A, Sholadoye, Tunde T, Kumar, Uttkarsh, Kingsley Oriji, Vaduneme, Varsheney, Vaibhav K, Samuel, Vasanth Mark, Agyekum-Gyimah, Vera O, Ifeanyichukwu Modekwe, Victor, Ojo, Victor, Abhulimen, Victor, Pérez Bocanegra, Víctor H, Avalos Herrera, Victor J, Etwire, Victor K, Ibukunoluwa Adeyeye, Victoria, Kumar, Vijay, Ismavel, Vijay A, John, Viju, Sehrawat, Vikram, Kudoh, Vincent, Kanna, Vinoth, Mukanyange, Violette, Michael, Vishal, Adobea, Vivian, Sam, Vivin Daniel, Ghansah, Wendy W, Asman, Wilfred K, Bhatti, William, Kagomi, Williams Y, Mehounou, Y.Edith, Mustapha, Yakubu, Oyewole, Yemisi, Edwin, Yenli, Oshodi, Yusuf A, Adofo-Asamoah, Yvonne, Ally, Zain, Imam, Zainab O, Shah, Zamir A, Lara Pérez, Zayra M, and Robertson, Zelda
- Abstract
Surgical site infection (SSI) remains the most common complication of surgery around the world. WHO does not make recommendations for changing gloves and instruments before wound closure owing to a lack of evidence. This study aimed to test whether a routine change of gloves and instruments before wound closure reduced abdominal SSI.
- Published
- 2022
- Full Text
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27. Covalent Proteomimetic Inhibitor of the Bacterial FtsQB Divisome Complex
- Author
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Paulussen, Felix M., Schouten, Gina K., Moertl, Carolin, Verheul, Jolanda, Hoekstra, Irma, Koningstein, Gregory M., Hutchins, George H., Alkir, Aslihan, Luirink, Rosa A., Geerke, Daan P., van Ulsen, Peter, den Blaauwen, Tanneke, Luirink, Joen, and Grossmann, Tom N.
- Abstract
The use of antibiotics is threatened by the emergence and spread of multidrug-resistant strains of bacteria. Thus, there is a need to develop antibiotics that address new targets. In this respect, the bacterial divisome, a multi-protein complex central to cell division, represents a potentially attractive target. Of particular interest is the FtsQB subcomplex that plays a decisive role in divisome assembly and peptidoglycan biogenesis in E. coli.Here, we report the structure-based design of a macrocyclic covalent inhibitor derived from a periplasmic region of FtsB that mediates its binding to FtsQ. The bioactive conformation of this motif was stabilized by a customized cross-link resulting in a tertiary structure mimetic with increased affinity for FtsQ. To increase activity, a covalent handle was incorporated, providing an inhibitor that impedes the interaction between FtsQ and FtsB irreversibly.The covalent inhibitor reduced the growth of an outer membrane-permeable E. colistrain, concurrent with the expected loss of FtsB localization, and also affected the infection of zebrafish larvae by a clinical E. colistrain. This first-in-class inhibitor of a divisome protein–protein interaction highlights the potential of proteomimetic molecules as inhibitors of challenging targets. In particular, the covalent mode-of-action can serve as an inspiration for future antibiotics that target protein–protein interactions.
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- 2022
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28. Der fortgesetzte Siegeszug der autonomen Auslegung — Anmerkung zu EuGH, Urt. v. 10.2.2022 – C-595/20 – UE ./. ShareWood Switzerland AG und VF
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Wilke, Felix M.
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- 2022
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29. The predictive role of early CRP values for one-year mortality in the first 2 d after acute myocardial infarction
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Alkouri, Ahmad, Cybularz, Maria, Mierke, Johannes, Nowack, Thomas, Biedermann, Jonathan, Ulbrich, Stefan, Fischer, Julia, Heidrich, Felix M., Jellinghaus, Stefanie, Speiser, Uwe, Linke, Axel, and Pfluecke, Christian
- Abstract
AbstractBackgroundAn excessive inflammatory reaction after acute myocardial infarction (AMI) is known to be harmful. New anti-inflammatory therapies are required.PurposeThis study assessed the predictive role of early CRP in patients with STEMI.MethodsA total of 1003 patients with STEMI were analysed. A total of 180 patients with proven infection were excluded. CRP after 12, 24 and 48 h after pain onset were evaluated.ResultsOf 823 patients, 103 (12.5%) died within one year after AMI. The deceased patients showed higher CRP, even after already 12 h (6 vs.13 mg/l, p < .001), 24 h (13 vs.25 mg/l, p < .001) and after 48 h (40 vs.92 mg/l, p < .001). A CRP of ≥8 mg/l, 12 h after AMI, was found in 45% and was independently associated with long-term mortality (OR: 2.7, p = .03), after 24 h: CRP ≥ 18 mg/l in 44% (OR: 2.5, p = .03), after 48 h: CRP ≥ 53 mg/l in 44% (OR 1.9, p = .03). Early CRP values correlated strongly with the later maximum value of CRP (p < .001).ConclusionsAlready early CRP values are accurate for risk-prediction following AMI. By identifying patients who are beginning to develop an excessive inflammatory response, it may be possible to identify those who benefit from anti-inflammatory therapies.
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- 2022
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30. Brown adipose tissue activation is not related to hypermetabolism in emphysematous chronic obstructive pulmonary disease patients
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Sanders, Karin J.C., Wierts, Roel, Marken Lichtenbelt, Wouter D., Vos‐Geelen, Judith, Plasqui, Guy, Kelders, Marco C.J.M., Schrauwen‐Hinderling, Vera B., Bucerius, Jan, Dingemans, Anne‐Marie C., Mottaghy, Felix M., and Schols, Annemie M.W.J.
- Abstract
Brown adipose tissue (BAT) has been primarily researched as a potential target for mitigating obesity. However, the physiological significance of BAT in relation to cachexia remains poorly understood. The objective of this study was to investigate the putative contribution of BAT on different components of energy metabolism in emphysematous chronic obstructive pulmonary disease (COPD) patients. Twenty COPD patients (mean ± SD age 62 ± 6, 50% female, median [range] BMI 22.4 [15.1–32.5] kg/m2and 85% low FFMI) were studied. Basal metabolic rate (BMR) was assessed by ventilated hood, total daily energy expenditure (TDEE) by doubly labelled water and physical activity by triaxial accelerometry. BMR was adjusted for fat‐free mass (FFM) as assessed by deuterium dilution. Analysis of BAT and WAT was conducted in a subset of ten patients and six age‐matched, gender‐matched and BMI‐matched healthy controls. BAT glucose uptake was assessed by means of cold‐stimulated integrated [18F]FDG positron‐emission tomography and magnetic resonance imaging. WAT was collected from subcutaneous abdominal biopsies to analyse metabolic and inflammatory gene expression levels. Lung function was assessed by spirometry and body plethysmography and systemic inflammation by high sensitivity C‐reactive protein. Mean TDEE was 2209 ± 394 kcal/day, and mean BMR was 1449 ± 214 kcal/day corresponding to 120% of predicted. FFM‐adjusted BMR did not correlate with lung function or C‐reactive protein. Upon cooling, energy expenditure increased, resulting in a non‐shivering thermogenesis of (median [range]) 20.1% [3.3–41.3] in patients and controls. Mean BAT glucose uptake was comparable between COPD and controls (1.5 [0.1–6.2] vs. 1.1 [0.7–3.9]). In addition, no correlation was found between BMR adjusted for FFM and BAT activity or between cold‐induced non‐shivering energy expenditure and BAT activity. Gene expression levels of the brown adipocyte or beige markers were also comparable between the groups. No (serious) adverse events were reported. Although COPD patients were hypermetabolic at rest, no correlation was found between BMR or TDEE and BAT activity. Furthermore, both BAT activity and gene expression levels of the brown adipocyte or beige markers were comparable between COPD patients and controls.
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- 2022
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31. Knee Injuries in the Elite American Football Player: A Descriptive Pictorial Imaging and Mechanism of Injury Review
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Hernandez, Ricardo J., Lamplot, Joseph D., Hammond, Kyle E., Joshi, Nirav B., Wong, Phillip K., Umpirrez, Monica, Singer, Adam, and Gonzalez, Felix M.
- Abstract
Musculoskeletal injuries are common in American football, with an incidence ranging from approximately 10 to 35 per 1000 playing hours. Injuries occur more commonly in games than in practice. Although several studies have analyzed specific injury types in football, this review aims to describe the most common knee injuries sustained by American football players and to review the existing literature pertaining to the radiologic findings used in the diagnosis of these injuries.
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- 2022
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32. Cooled Radiofrequency Ablation for Chronic Joint Pain Secondary to Hip and Shoulder Osteoarthritis
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Kallas, Omar N., Nezami, Nariman, Singer, Adam D., Wong, Philip, Kokabi, Nima, Bercu, Zachary L., Umpierrez, Monica, Tran, Andrew, Reimer, Nickolas B., Oskouei, Shervin V., and Gonzalez, Felix M.
- Abstract
Radiofrequency ablation could be an effective nonsurgical alternative for the management of chronic hip and glenohumeral joint pain secondary to moderate to severe osteoarthritis that is refractory to traditional management.
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- 2022
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33. Teaching of Nuclear Cardiology in Times of Pandemic: Transfer of a Case-based Interactive Course from Classroom to Distance Learning
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Bell, Laura, Lemos, Martin, Mottaghy, Felix M., Lindner, Oliver, and Heinzel, Alexander
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- 2022
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34. Resveratrol treatment does not reduce arterial inflammation in males at risk of type 2 diabetes: a randomized crossover trial
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Boswijk, Ellen, de Ligt, Marlies, Habets, Marie-Fleur J, Mingels, Alma M.A., van Marken Lichtenbelt, Wouter D., Mottaghy, Felix M., Schrauwen, Patrick, Wildberger, Joachim E., and Bucerius, Jan
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- 2022
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35. Estimating the resource intensity of the Internet: A meta-model to account for cloud-based services in LCA
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Ullrich, Noel, Piontek, Felix M., Herrmann, Constantin, Saraev, Alexandra, and Viere, Tobias
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According to an analysis by the International Energy Agency based on industry data from cisco, the internet protocol (IP) data traffic has more than doubled in 2019 compared to 2016. In addition to an increased number of people and devices with internet access, new trends on the application level can be identified as drivers of this exponential growth. Carsharing, Industry 4.0, or smart home applications are examples of the rising importance of the Internet within new product systems. Therefore, it is indispensable for environmental analyses to account for both, the positive and negative effects of increased internet usage. The existing approaches to account for the resource consumption of information and communication technology (ICT) equipment have different system boundaries or focus exclusively on energy intensity, what offers the basis for further development.
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- 2022
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36. The role of LC3C N-terminus in autophagosome expansion
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Ballesteros, Uxue, Etxaniz, Asier, Iriondo, Marina N., Varela, Yaiza R., Bermejillo, David, Montes, Lidia Ruth, Goñi, Felix M., and Alonso, Alicia
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- 2024
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37. Cardiolipin and ceramide in phospholipid bilayers: Phase separation and implications for autophagy
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Varela, Yaiza R., Gonzalez-Ramirez, Emilio J., Iriondo, Marina N., Ballesteros, Uxue, Etxaniz, Asier, Montes, Lidia Ruth, Goñi, Felix M., and Alonso, Alicia
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- 2024
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38. Book review
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Edoho, Felix M.
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- 2021
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39. Locking and loading the bullet against micro-calcification
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Florea, Alexandru, Morgenroth, Agnieszka, Bucerius, Jan, Schurgers, Leon J, and Mottaghy, Felix M
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- 2021
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40. Myths revisited
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Beck, Felix M.
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Management -- Methods ,Pricing -- Evaluation ,Cost control -- Management ,Rate of return -- Management ,Mortgage banks -- Management ,Mortgages -- Marketing ,Banking, finance and accounting industries ,Business ,Real estate industry - Abstract
MYTHS REVISITED Some conventional wisdom in this business needs to be challenged. Separating myths from reality is critical in the mortgage banking business. Back in the spring of 1988, in [...]
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- 1991
41. Mechanical switches snap back
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Castro, Felix M.
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Switches -- Design and construction ,Business ,Engineering and manufacturing industries ,Metals, metalworking and machinery industries - Published
- 1991
42. Photophobia Associated with Traumatic Brain Injury: A Systematic Review and Meta-analysis
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Merezhinskaya, Natalya, Mallia, Rita K., Park, DoHwan, Millian-Morell, Lymarie, and Barker, Felix M.
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Supplemental digital content is available in the text.
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- 2021
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43. Is there a safe age for vaccinating infants with tetravalent rhesus-human reassortant rotavirus vaccine?
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Gargiullo, Paul M., Murphy, Trudy V., Davis, Robert L., Rothman, Kenneth J., Arellano, Felix M., Young-Xu, Yinong, and Simonsen, Lone
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Infants -- Health aspects ,Vaccination -- Dosage and administration ,Vaccination -- Standards ,Rotavirus infections -- Prevention ,Health - Published
- 2006
44. Dose Setting for Dermal Absorption Studies on Dried Foliar Residues
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Morgan, Neil, Hewitt, Nicola J, Felkers, Edgars, Wiemann, Christiane, Kluxen, Felix M, and Kuster, Christian J
- Abstract
Currently, the standard approach to estimate systemic exposure of workers after contact with dried pesticide residues on crops during re-entry activities relies on using the highest identified dermal absorption value for aqueous spray dilutions. However, recent dermal absorption studies with dried residues and their respective in-use dilutions have shown that this is likely to significantly overestimate their dermal penetration potential and, thus, predicted systemic exposure. The choice of appropriate dose levels for these dermal absorption studies has not been defined. Moreover, actual skin loading during re-entry tasks may differ significantly from that achieved by applying a fixed volume of an aqueous dilution, which is the standard practice in generic dermal absorption studies. To address this, we propose an approach to dose setting for dried residue studies within the current European risk assessment framework. Skin loading for studies can be calculated from the existing exposure algorithms and by taking appropriate body surface areas into account. Thus, skin loading in studies will vary depending on the exact nature and duration of the task and the region of the body exposed, reflecting actual exposure scenarios.
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- 2021
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45. Acousto-optic modulation of a wavelength-scale waveguide
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Sarabalis, Christopher J., Van Laer, Raphaël, Patel, Rishi N., Dahmani, Yanni D., Jiang, Wentao, Mayor, Felix M., and Safavi-Naeini, Amir H.
- Abstract
Since the advent of the laser, acousto-optic modulators have been an important tool for controlling light. Recent advances in on-chip lithium niobate waveguide technology present new opportunities for these devices. We demonstrate a collinear acousto-optic modulator in a suspended film of lithium niobate employing a high-confinement, wavelength-scale waveguide. By strongly confining the optical and mechanical waves, this modulator improves a figure-of-merit that accounts for both acousto-optic and electro-mechanical efficiency by orders of magnitude. Our device demonstration marks a significant technological advance in acousto-optics that promises a novel class of compact and low-power frequency shifters, tunable filters, non-magnetic isolators, and beam deflectors.
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- 2021
46. Autonome Auslegung und kein Ende? — Anmerkung zu EuGH, Urt. v. 11.11.2020 – C-433/19 – Ellmes Property Services ./. SP
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Wilke, Felix M.
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- 2021
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47. CELEBRATING 30 YEARS OF HISTORY IRELAND.
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Larkin, Felix M.
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IRISH history ,CULTURAL centers ,COUNTY councils - Abstract
The article announces 30th anniversary celebration of History Ireland, featuring an exhibition of its front covers at the Lexicon Library, including its commitment to public history, its role in bridging the gap between academic and public history, and its ancillary ventures.
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- 2023
48. Transdisciplinary sustainability research in real-world labs: success factors and methods for change
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Bergmann, Matthias, Schäpke, Niko, Marg, Oskar, Stelzer, Franziska, Lang, Daniel J., Bossert, Michael, Gantert, Marius, Häußler, Elke, Marquardt, Editha, Piontek, Felix M., Potthast, Thomas, Rhodius, Regina, Rudolph, Matthias, Ruddat, Michael, Seebacher, Andreas, and Sußmann, Nico
- Abstract
The transdisciplinary research mode has gained prominence in the research on and for sustainability transformations. Yet, solution-oriented research addressing complex sustainability problems has become complex itself, with new transdisciplinary research formats being developed and tested for this purpose. Application of new formats offers learning potentials from experience. To this end, we accompanied fourteen research projects conceptualized as real-world labs (RwLs) from 2015 to 2018. RwLs were part of a funding program on ‘Science for Sustainability’ in the German federal state of Baden-Württemberg. Here, we combine conceptual and empirical work to a structured collection of experiences and provide a comprehensive account of RwLs. First, we outline characteristics of RwLs as transformation oriented, transdisciplinary research approach, using experiments, enabling learning and having a long-term orientation. Second, we outline eleven success factors and concrete design notes we gained through a survey of the 14 RwLs: (1) find the right balance between scientific and societal aims, (2) address the practitioners needs and restrictions, (3) make use of the experimentation concept, (4) actively communicate, (5) develop a ‘collaboration culture’, (6) be attached to concrete sites, (7) create lasting impact and transferability, (8) plan for sufficient time and financial means, (9) adaptability, (10) research-based learning, and (11) recognize dependency on external actors. Characteristics and success factors are combined to illustrate practical challenges in RwLs. Third, we show which methods could be used to cope with challenges in RwLs. We conclude discussing the state of debate on RwLs and outline future avenues of research.
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- 2021
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49. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
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Klionsky, Daniel J., Abdel-Aziz, Amal Kamal, Abdelfatah, Sara, Abdellatif, Mahmoud, Abdoli, Asghar, Abel, Steffen, Abeliovich, Hagai, Abildgaard, Marie H., Abudu, Yakubu Princely, Acevedo-Arozena, Abraham, Adamopoulos, Iannis E., Adeli, Khosrow, Adolph, Timon E., Adornetto, Annagrazia, Aflaki, Elma, Agam, Galila, Agarwal, Anupam, Aggarwal, Bharat B., Agnello, Maria, Agostinis, Patrizia, Agrewala, Javed N., Agrotis, Alexander, Aguilar, Patricia V., Ahmad, S. Tariq, Ahmed, Zubair M., Ahumada-Castro, Ulises, Aits, Sonja, Aizawa, Shu, Akkoc, Yunus, Akoumianaki, Tonia, Akpinar, Hafize Aysin, Al-Abd, Ahmed M., Al-Akra, Lina, Al-Gharaibeh, Abeer, Alaoui-Jamali, Moulay A., Alberti, Simon, Alcocer-Gómez, Elísabet, Alessandri, Cristiano, Ali, Muhammad, Alim Al-Bari, M. Abdul, Aliwaini, Saeb, Alizadeh, Javad, Almacellas, Eugènia, Almasan, Alexandru, Alonso, Alicia, Alonso, Guillermo D., Altan-Bonnet, Nihal, Altieri, Dario C., Álvarez, Élida M. C., Alves, Sara, Alves da Costa, Cristine, Alzaharna, Mazen M., Amadio, Marialaura, Amantini, Consuelo, Amaral, Cristina, Ambrosio, Susanna, Amer, Amal O., Ammanathan, Veena, An, Zhenyi, Andersen, Stig U., Andrabi, Shaida A., Andrade-Silva, Magaiver, Andres, Allen M., Angelini, Sabrina, Ann, David, Anozie, Uche C., Ansari, Mohammad Y., Antas, Pedro, Antebi, Adam, Antón, Zuriñe, Anwar, Tahira, Apetoh, Lionel, Apostolova, Nadezda, Araki, Toshiyuki, Araki, Yasuhiro, Arasaki, Kohei, Araújo, Wagner L., Araya, Jun, Arden, Catherine, Arévalo, Maria-Angeles, Arguelles, Sandro, Arias, Esperanza, Arikkath, Jyothi, Arimoto, Hirokazu, Ariosa, Aileen R., Armstrong-James, Darius, Arnauné-Pelloquin, Laetitia, Aroca, Angeles, Arroyo, Daniela S., Arsov, Ivica, Artero, Rubén, Asaro, Dalia Maria Lucia, Aschner, Michael, Ashrafizadeh, Milad, Ashur-Fabian, Osnat, Atanasov, Atanas G., Au, Alicia K., Auberger, Patrick, Auner, Holger W., Aurelian, Laure, Autelli, Riccardo, Avagliano, Laura, Ávalos, Yenniffer, Aveic, Sanja, Aveleira, Célia Alexandra, Avin-Wittenberg, Tamar, Aydin, Yucel, Ayton, Scott, Ayyadevara, Srinivas, Azzopardi, Maria, Baba, Misuzu, Backer, Jonathan M., Backues, Steven K., Bae, Dong-Hun, Bae, Ok-Nam, Bae, Soo Han, Baehrecke, Eric H., Baek, Ahruem, Baek, Seung-Hoon, Baek, Sung Hee, Bagetta, Giacinto, Bagniewska-Zadworna, Agnieszka, Bai, Hua, Bai, Jie, Bai, Xiyuan, Bai, Yidong, Bairagi, Nandadulal, Baksi, Shounak, Balbi, Teresa, Baldari, Cosima T., Balduini, Walter, Ballabio, Andrea, Ballester, Maria, Balazadeh, Salma, Balzan, Rena, Bandopadhyay, Rina, Banerjee, Sreeparna, Banerjee, Sulagna, Bánréti, Ágnes, Bao, Yan, Baptista, Mauricio S., Baracca, Alessandra, Barbati, Cristiana, Bargiela, Ariadna, Barilà, Daniela, Barlow, Peter G., Barmada, Sami J., Barreiro, Esther, Barreto, George E., Bartek, Jiri, Bartel, Bonnie, Bartolome, Alberto, Barve, Gaurav R., Basagoudanavar, Suresh H., Bassham, Diane C., Bast, Robert C., Basu, Alakananda, Batoko, Henri, Batten, Isabella, Baulieu, Etienne E., Baumgarner, Bradley L., Bayry, Jagadeesh, Beale, Rupert, Beau, Isabelle, Beaumatin, Florian, Bechara, Luiz R.G., Beck, George R., Beers, Michael F., Begun, Jakob, Behrends, Christian, Behrens, Georg M.N., Bei, Roberto, Bejarano, Eloy, Bel, Shai, Behl, Christian, Belaid, Amine, Belgareh-Touzé, Naïma, Bellarosa, Cristina, Belleudi, Francesca, Belló Pérez, Melissa, Bello-Morales, Raquel, Beltran, Jackeline Soares de Oliveira, Beltran, Sebastián, Benbrook, Doris Mangiaracina, Bendorius, Mykolas, Benitez, Bruno A., Benito-Cuesta, Irene, Bensalem, Julien, Berchtold, Martin W., Berezowska, Sabina, Bergamaschi, Daniele, Bergami, Matteo, Bergmann, Andreas, Berliocchi, Laura, Berlioz-Torrent, Clarisse, Bernard, Amélie, Berthoux, Lionel, Besirli, Cagri G., Besteiro, Sebastien, Betin, Virginie M., Beyaert, Rudi, Bezbradica, Jelena S., Bhaskar, Kiran, Bhatia-Kissova, Ingrid, Bhattacharya, Resham, Bhattacharya, Sujoy, Bhattacharyya, Shalmoli, Bhuiyan, Md. Shenuarin, Bhutia, Sujit Kumar, Bi, Lanrong, Bi, Xiaolin, Biden, Trevor J., Bijian, Krikor, Billes, Viktor A., Binart, Nadine, Bincoletto, Claudia, Birgisdottir, Asa B., Bjorkoy, Geir, Blanco, Gonzalo, Blas-Garcia, Ana, Blasiak, Janusz, Blomgran, Robert, Blomgren, Klas, Blum, Janice S., Boada-Romero, Emilio, Boban, Mirta, Boesze-Battaglia, Kathleen, Boeuf, Philippe, Boland, Barry, Bomont, Pascale, Bonaldo, Paolo, Bonam, Srinivasa Reddy, Bonfili, Laura, Bonifacino, Juan S., Boone, Brian A., Bootman, Martin D., Bordi, Matteo, Borner, Christoph, Bornhauser, Beat C., Borthakur, Gautam, Bosch, Jürgen, Bose, Santanu, Botana, Luis M., Botas, Juan, Boulanger, Chantal M., Boulton, Michael E., Bourdenx, Mathieu, Bourgeois, Benjamin, Bourke, Nollaig M., Bousquet, Guilhem, Boya, Patricia, Bozhkov, Peter V., Bozi, Luiz H. M., Bozkurt, Tolga O., Brackney, Doug E., Brandts, Christian H., Braun, Ralf J., Braus, Gerhard H., Bravo-Sagua, Roberto, Bravo-San Pedro, José M., Brest, Patrick, Bringer, Marie-Agnès, Briones-Herrera, Alfredo, Broaddus, V. Courtney, Brodersen, Peter, Brodsky, Jeffrey L., Brody, Steven L., Bronson, Paola G., Bronstein, Jeff M., Brown, Carolyn N., Brown, Rhoderick E., Brum, Patricia C., Brumell, John H., Brunetti-Pierri, Nicola, Bruno, Daniele, Bryson-Richardson, Robert J., Bucci, Cecilia, Buchrieser, Carmen, Bueno, Marta, Buitrago-Molina, Laura Elisa, Buraschi, Simone, Buch, Shilpa, Buchan, J. Ross, Buckingham, Erin M., Budak, Hikmet, Budini, Mauricio, Bultynck, Geert, Burada, Florin, Burgoyne, Joseph R., Burón, M. Isabel, Bustos, Victor, Büttner, Sabrina, Butturini, Elena, Byrd, Aaron, Cabas, Isabel, Cabrera-Benitez, Sandra, Cadwell, Ken, Cai, Jingjing, Cai, Lu, Cai, Qian, Cairó, Montserrat, Calbet, Jose A., Caldwell, Guy A., Caldwell, Kim A., Call, Jarrod A., Calvani, Riccardo, Calvo, Ana C., Calvo-Rubio Barrera, Miguel, Camara, Niels OS, Camonis, Jacques H., Camougrand, Nadine, Campanella, Michelangelo, Campbell, Edward M., Campbell-Valois, François-Xavier, Campello, Silvia, Campesi, Ilaria, Campos, Juliane C., Camuzard, Olivier, Cancino, Jorge, Candido de Almeida, Danilo, Canesi, Laura, Caniggia, Isabella, Canonico, Barbara, Cantí, Carles, Cao, Bin, Caraglia, Michele, Caramés, Beatriz, Carchman, Evie H., Cardenal-Muñoz, Elena, Cardenas, Cesar, Cardenas, Luis, Cardoso, Sandra M., Carew, Jennifer S., Carle, Georges F., Carleton, Gillian, Carloni, Silvia, Carmona-Gutierrez, Didac, Carneiro, Leticia A., Carnevali, Oliana, Carosi, Julian M., Carra, Serena, Carrier, Alice, Carrier, Lucie, Carroll, Bernadette, Carter, A. Brent, Carvalho, Andreia Neves, Casanova, Magali, Casas, Caty, Casas, Josefina, Cassioli, Chiara, Castillo, Eliseo F., Castillo, Karen, Castillo-Lluva, Sonia, Castoldi, Francesca, Castori, Marco, Castro, Ariel F., Castro-Caldas, Margarida, Castro-Hernandez, Javier, Castro-Obregon, Susana, Catz, Sergio D., Cavadas, Claudia, Cavaliere, Federica, Cavallini, Gabriella, Cavinato, Maria, Cayuela, Maria L., Cebollada Rica, Paula, Cecarini, Valentina, Cecconi, Francesco, Cechowska-Pasko, Marzanna, Cenci, Simone, Ceperuelo-Mallafré, Victòria, Cerqueira, João J., Cerutti, Janete M., Cervia, Davide, Cetintas, Vildan Bozok, Cetrullo, Silvia, Chae, Han-Jung, Chagin, Andrei S., Chai, Chee-Yin, Chakrabarti, Gopal, Chakrabarti, Oishee, Chakraborty, Tapas, Chakraborty, Trinad, Chami, Mounia, Chamilos, Georgios, Chan, David W., Chan, Edmond Y. W., Chan, Edward D., Chan, H.Y. Edwin, Chan, Helen H., Chan, Hung, Chan, Matthew T.V., Chan, Yau Sang, Chandra, Partha K., Chang, Chih-Peng, Chang, Chunmei, Chang, Hao-Chun, Chang, Kai, Chao, Jie, Chapman, Tracey, Charlet-Berguerand, Nicolas, Chatterjee, Samrat, Chaube, Shail K., Chaudhary, Anu, Chauhan, Santosh, Chaum, Edward, Checler, Frédéric, Cheetham, Michael E., Chen, Chang-Shi, Chen, Guang-Chao, Chen, Jian-Fu, Chen, Liam L., Chen, Leilei, Chen, Lin, Chen, Mingliang, Chen, Mu-Kuan, Chen, Ning, Chen, Quan, Chen, Ruey-Hwa, Chen, Shi, Chen, Wei, Chen, Weiqiang, Chen, Xin-Ming, Chen, Xiong-Wen, Chen, Xu, Chen, Yan, Chen, Ye-Guang, Chen, Yingyu, Chen, Yongqiang, Chen, Yu-Jen, Chen, Yue-Qin, Chen, Zhefan Stephen, Chen, Zhi, Chen, Zhi-Hua, Chen, Zhijian J., Chen, Zhixiang, Cheng, Hanhua, Cheng, Jun, Cheng, Shi-Yuan, Cheng, Wei, Cheng, Xiaodong, Cheng, Xiu-Tang, Cheng, Yiyun, Cheng, Zhiyong, Chen, Zhong, Cheong, Heesun, Cheong, Jit Kong, Chernyak, Boris V., Cherry, Sara, Cheung, Chi Fai Randy, Cheung, Chun Hei Antonio, Cheung, King-Ho, Chevet, Eric, Chi, Richard J., Chiang, Alan Kwok Shing, Chiaradonna, Ferdinando, Chiarelli, Roberto, Chiariello, Mario, Chica, Nathalia, Chiocca, Susanna, Chiong, Mario, Chiou, Shih-Hwa, Chiramel, Abhilash I., Chiurchiù, Valerio, Cho, Dong-Hyung, Choe, Seong-Kyu, Choi, Augustine M.K., Choi, Mary E., Choudhury, Kamalika Roy, Chow, Norman S., Chu, Charleen T., Chua, Jason P., Chua, John Jia En, Chung, Hyewon, Chung, Kin Pan, Chung, Seockhoon, Chung, So-Hyang, Chung, Yuen-Li, Cianfanelli, Valentina, Ciechomska, Iwona A., Cifuentes, Mariana, Cinque, Laura, Cirak, Sebahattin, Cirone, Mara, Clague, Michael J., Clarke, Robert, Clementi, Emilio, Coccia, Eliana M., Codogno, Patrice, Cohen, Ehud, Cohen, Mickael M., Colasanti, Tania, Colasuonno, Fiorella, Colbert, Robert A., Colell, Anna, Čolić, Miodrag, Coll, Nuria S., Collins, Mark O., Colombo, María I., Colón-Ramos, Daniel A., Combaret, Lydie, Comincini, Sergio, Cominetti, Márcia R., Consiglio, Antonella, Conte, Andrea, Conti, Fabrizio, Contu, Viorica Raluca, Cookson, Mark R., Coombs, Kevin M., Coppens, Isabelle, Corasaniti, Maria Tiziana, Corkery, Dale P., Cordes, Nils, Cortese, Katia, Costa, Maria do Carmo, Costantino, Sarah, Costelli, Paola, Coto-Montes, Ana, Crack, Peter J., Crespo, Jose L., Criollo, Alfredo, Crippa, Valeria, Cristofani, Riccardo, Csizmadia, Tamas, Cuadrado, Antonio, Cui, Bing, Cui, Jun, Cui, Yixian, Cui, Yong, Culetto, Emmanuel, Cumino, Andrea C., Cybulsky, Andrey V., Czaja, Mark J., Czuczwar, Stanislaw J., D’Adamo, Stefania, D’Amelio, Marcello, D’Arcangelo, Daniela, D’Lugos, Andrew C., D’Orazi, Gabriella, da Silva, James A., Dafsari, Hormos Salimi, Dagda, Ruben K., Dagdas, Yasin, Daglia, Maria, Dai, Xiaoxia, Dai, Yun, Dai, Yuyuan, Dal Col, Jessica, Dalhaimer, Paul, Dalla Valle, Luisa, Dallenga, Tobias, Dalmasso, Guillaume, Damme, Markus, Dando, Ilaria, Dantuma, Nico P., Darling, April L., Das, Hiranmoy, Dasarathy, Srinivasan, Dasari, Santosh K., Dash, Srikanta, Daumke, Oliver, Dauphinee, Adrian N., Davies, Jeffrey S., Dávila, Valeria A., Davis, Roger J., Davis, Tanja, Dayalan Naidu, Sharadha, De Amicis, Francesca, De Bosscher, Karolien, De Felice, Francesca, De Franceschi, Lucia, De Leonibus, Chiara, de Mattos Barbosa, Mayara G., De Meyer, Guido R.Y., De Milito, Angelo, De Nunzio, Cosimo, De Palma, Clara, De Santi, Mauro, De Virgilio, Claudio, De Zio, Daniela, Debnath, Jayanta, DeBosch, Brian J., Decuypere, Jean-Paul, Deehan, Mark A., Deflorian, Gianluca, DeGregori, James, Dehay, Benjamin, Del Rio, Gabriel, Delaney, Joe R., Delbridge, Lea M. D., Delorme-Axford, Elizabeth, Delpino, M. Victoria, Demarchi, Francesca, Dembitz, Vilma, Demers, Nicholas D., Deng, Hongbin, Deng, Zhiqiang, Dengjel, Joern, Dent, Paul, Denton, Donna, DePamphilis, Melvin L., Der, Channing J., Deretic, Vojo, Descoteaux, Albert, Devis, Laura, Devkota, Sushil, Devuyst, Olivier, Dewson, Grant, Dharmasivam, Mahendiran, Dhiman, Rohan, di Bernardo, Diego, Di Cristina, Manlio, Di Domenico, Fabio, Di Fazio, Pietro, Di Fonzo, Alessio, Di Guardo, Giovanni, Di Guglielmo, Gianni M., Di Leo, Luca, Di Malta, Chiara, Di Nardo, Alessia, Di Rienzo, Martina, Di Sano, Federica, Diallinas, George, Diao, Jiajie, Diaz-Araya, Guillermo, Díaz-Laviada, Inés, Dickinson, Jared M., Diederich, Marc, Dieudé, Mélanie, Dikic, Ivan, Ding, Shiping, Ding, Wen-Xing, Dini, Luciana, Dinić, Jelena, Dinic, Miroslav, Dinkova-Kostova, Albena T., Dionne, Marc S., Distler, Jörg H.W., Diwan, Abhinav, Dixon, Ian M.C., Djavaheri-Mergny, Mojgan, Dobrinski, Ina, Dobrovinskaya, Oxana, Dobrowolski, Radek, Dobson, Renwick C.J., Đokić, Jelena, Dokmeci Emre, Serap, Donadelli, Massimo, Dong, Bo, Dong, Xiaonan, Dong, Zhiwu, 2nd Dorn, Gerald W., Dotsch, Volker, Dou, Huan, Dou, Juan, Dowaidar, Moataz, Dridi, Sami, Drucker, Liat, Du, Ailian, Du, Caigan, Du, Guangwei, Du, Hai-Ning, Du, Li-Lin, du Toit, André, Duan, Shao-Bin, Duan, Xiaoqiong, Duarte, Sónia P., Dubrovska, Anna, Dunlop, Elaine A., Dupont, Nicolas, Durán, Raúl V., Dwarakanath, Bilikere S., Dyshlovoy, Sergey A., Ebrahimi-Fakhari, Darius, Eckhart, Leopold, Edelstein, Charles L., Efferth, Thomas, Eftekharpour, Eftekhar, Eichinger, Ludwig, Eid, Nabil, Eisenberg, Tobias, Eissa, N. Tony, Eissa, Sanaa, Ejarque, Miriam, El Andaloussi, Abdeljabar, El-Hage, Nazira, El-Naggar, Shahenda, Eleuteri, Anna Maria, El-Shafey, Eman S., Elgendy, Mohamed, Eliopoulos, Aristides G., Elizalde, María M., Elks, Philip M., Elsasser, Hans-Peter, Elsherbiny, Eslam S., Emerling, Brooke M., Emre, N. C. Tolga, Eng, Christina H., Engedal, Nikolai, Engelbrecht, Anna-Mart, Engelsen, Agnete S.T., Enserink, Jorrit M., Escalante, Ricardo, Esclatine, Audrey, Escobar-Henriques, Mafalda, Eskelinen, Eeva-Liisa, Espert, Lucile, Eusebio, Makandjou-Ola, Fabrias, Gemma, Fabrizi, Cinzia, Facchiano, Antonio, Facchiano, Francesco, Fadeel, Bengt, Fader, Claudio, Faesen, Alex C., Fairlie, W. Douglas, Falcó, Alberto, Falkenburger, Bjorn H., Fan, Daping, Fan, Jie, Fan, Yanbo, Fang, Evandro F., Fang, Yanshan, Fang, Yognqi, Fanto, Manolis, Farfel-Becker, Tamar, Faure, Mathias, Fazeli, Gholamreza, Fedele, Anthony O., Feldman, Arthur M., Feng, Du, Feng, Jiachun, Feng, Lifeng, Feng, Yibin, Feng, Yuchen, Feng, Wei, Fenz Araujo, Thais, Ferguson, Thomas A., Fernández, Álvaro F., Fernandez-Checa, Jose C., Fernández-Veledo, Sonia, Fernie, Alisdair R., Ferrante, Anthony W., Ferraresi, Alessandra, Ferrari, Merari F., Ferreira, Julio C.B., Ferro-Novick, Susan, Figueras, Antonio, Filadi, Riccardo, Filigheddu, Nicoletta, Filippi-Chiela, Eduardo, Filomeni, Giuseppe, Fimia, Gian Maria, Fineschi, Vittorio, Finetti, Francesca, Finkbeiner, Steven, Fisher, Edward A., Fisher, Paul B., Flamigni, Flavio, Fliesler, Steven J., Flo, Trude H., Florance, Ida, Florey, Oliver, Florio, Tullio, Fodor, Erika, Follo, Carlo, Fon, Edward A., Forlino, Antonella, Fornai, Francesco, Fortini, Paola, Fracassi, Anna, Fraldi, Alessandro, Franco, Brunella, Franco, Rodrigo, Franconi, Flavia, Frankel, Lisa B., Friedman, Scott L., Fröhlich, Leopold F., Frühbeck, Gema, Fuentes, Jose M., Fujiki, Yukio, Fujita, Naonobu, Fujiwara, Yuuki, Fukuda, Mitsunori, Fulda, Simone, Furic, Luc, Furuya, Norihiko, Fusco, Carmela, Gack, Michaela U., Gaffke, Lidia, Galadari, Sehamuddin, Galasso, Alessia, Galindo, Maria F., Gallolu Kankanamalage, Sachith, Galluzzi, Lorenzo, Galy, Vincent, Gammoh, Noor, Gan, Boyi, Ganley, Ian G., Gao, Feng, Gao, Hui, Gao, Minghui, Gao, Ping, Gao, Shou-Jiang, Gao, Wentao, Gao, Xiaobo, Garcera, Ana, Garcia, Maria Noé, Garcia, Verónica E., García-Del Portillo, Francisco, Garcia-Escudero, Vega, Garcia-Garcia, Aracely, Garcia-Macia, Marina, García-Moreno, Diana, Garcia-Ruiz, Carmen, García-Sanz, Patricia, Garg, Abhishek D., Gargini, Ricardo, Garofalo, Tina, Garry, Robert F., Gassen, Nils C., Gatica, Damian, Ge, Liang, Ge, Wanzhong, Geiss-Friedlander, Ruth, Gelfi, Cecilia, Genschik, Pascal, Gentle, Ian E., Gerbino, Valeria, Gerhardt, Christoph, Germain, Kyla, Germain, Marc, Gewirtz, David A., Ghasemipour Afshar, Elham, Ghavami, Saeid, Ghigo, Alessandra, Ghosh, Manosij, Giamas, Georgios, Giampietri, Claudia, Giatromanolaki, Alexandra, Gibson, Gary E., Gibson, Spencer B., Ginet, Vanessa, Giniger, Edward, Giorgi, Carlotta, Girao, Henrique, Girardin, Stephen E., Giridharan, Mridhula, Giuliano, Sandy, Giulivi, Cecilia, Giuriato, Sylvie, Giustiniani, Julien, Gluschko, Alexander, Goder, Veit, Goginashvili, Alexander, Golab, Jakub, Goldstone, David C., Golebiewska, Anna, Gomes, Luciana R., Gomez, Rodrigo, Gómez-Sánchez, Rubén, Gomez-Puerto, Maria Catalina, Gomez-Sintes, Raquel, Gong, Qingqiu, Goni, Felix M., González-Gallego, Javier, Gonzalez-Hernandez, Tomas, Gonzalez-Polo, Rosa A., Gonzalez-Reyes, Jose A., González-Rodríguez, Patricia, Goping, Ing Swie, Gorbatyuk, Marina S., Gorbunov, Nikolai V., Görgülü, Kıvanç, Gorojod, Roxana M., Gorski, Sharon M., Goruppi, Sandro, Gotor, Cecilia, Gottlieb, Roberta A., Gozes, Illana, Gozuacik, Devrim, Graef, Martin, Gräler, Markus H., Granatiero, Veronica, Grasso, Daniel, Gray, Joshua P., Green, Douglas R., Greenhough, Alexander, Gregory, Stephen L., Griffin, Edward F., Grinstaff, Mark W., Gros, Frederic, Grose, Charles, Gross, Angelina S., Gruber, Florian, Grumati, Paolo, Grune, Tilman, Gu, Xueyan, Guan, Jun-Lin, Guardia, Carlos M., Guda, Kishore, Guerra, Flora, Guerri, Consuelo, Guha, Prasun, Guillén, Carlos, Gujar, Shashi, Gukovskaya, Anna, Gukovsky, Ilya, Gunst, Jan, Günther, Andreas, Guntur, Anyonya R., Guo, Chuanyong, Guo, Chun, Guo, Hongqing, Guo, Lian-Wang, Guo, Ming, Gupta, Pawan, Gupta, Shashi Kumar, Gupta, Swapnil, Gupta, Veer Bala, Gupta, Vivek, Gustafsson, Asa B., Gutterman, David D., H.B., Ranjitha, Haapasalo, Annakaisa, Haber, James E., Hać, Aleksandra, Hadano, Shinji, Hafrén, Anders J., Haidar, Mansour, Hall, Belinda S., Halldén, Gunnel, Hamacher-Brady, Anne, Hamann, Andrea, Hamasaki, Maho, Han, Weidong, Hansen, Malene, Hanson, Phyllis I., Hao, Zijian, Harada, Masaru, Harhaji-Trajkovic, Ljubica, Hariharan, Nirmala, Haroon, Nigil, Harris, James, Hasegawa, Takafumi, Hasima Nagoor, Noor, Haspel, Jeffrey A., Haucke, Volker, Hawkins, Wayne D., Hay, Bruce A., Haynes, Cole M., Hayrabedyan, Soren B., Hays, Thomas S., He, Congcong, He, Qin, He, Rong-Rong, He, You-Wen, He, Yu-Ying, Heakal, Yasser, Heberle, Alexander M., Hejtmancik, J. Fielding, Helgason, Gudmundur Vignir, Henkel, Vanessa, Herb, Marc, Hergovich, Alexander, Herman-Antosiewicz, Anna, Hernández, Agustín, Hernandez, Carlos, Hernandez-Diaz, Sergio, Hernandez-Gea, Virginia, Herpin, Amaury, Herreros, Judit, Hervás, Javier H., Hesselson, Daniel, Hetz, Claudio, Heussler, Volker T., Higuchi, Yujiro, Hilfiker, Sabine, Hill, Joseph A., Hlavacek, William S., Ho, Emmanuel A., Ho, Idy H.T., Ho, Philip Wing-Lok, Ho, Shu-Leong, Ho, Wan Yun, Hobbs, G. Aaron, Hochstrasser, Mark, Hoet, Peter H.M., Hofius, Daniel, Hofman, Paul, Höhn, Annika, Holmberg, Carina I., Hombrebueno, Jose R., Hong, Chang-Won, Hong, Yi-Ren, Hooper, Lora V., Hoppe, Thorsten, Horos, Rastislav, Hoshida, Yujin, Hsin, I-Lun, Hsu, Hsin-Yun, Hu, Bing, Hu, Dong, Hu, Li-Fang, Hu, Ming Chang, Hu, Ronggui, Hu, Wei, Hu, Yu-Chen, Hu, Zhuo-Wei, Hua, Fang, Hua, Jinlian, Hua, Yingqi, Huan, Chongmin, Huang, Canhua, Huang, Chuanshu, Huang, Chuanxin, Huang, Chunling, Huang, Haishan, Huang, Kun, Huang, Michael L.H., Huang, Rui, Huang, Shan, Huang, Tianzhi, Huang, Xing, Huang, Yuxiang Jack, Huber, Tobias B., Hubert, Virginie, Hubner, Christian A., Hughes, Stephanie M., Hughes, William E., Humbert, Magali, Hummer, Gerhard, Hurley, James H., Hussain, Sabah, Hussain, Salik, Hussey, Patrick J., Hutabarat, Martina, Hwang, Hui-Yun, Hwang, Seungmin, Ieni, Antonio, Ikeda, Fumiyo, Imagawa, Yusuke, Imai, Yuzuru, Imbriano, Carol, Imoto, Masaya, Inman, Denise M., Inoki, Ken, Iovanna, Juan, Iozzo, Renato V., Ippolito, Giuseppe, Irazoqui, Javier E., Iribarren, Pablo, Ishaq, Mohd, Ishikawa, Makoto, Ishimwe, Nestor, Isidoro, Ciro, Ismail, Nahed, Issazadeh-Navikas, Shohreh, Itakura, Eisuke, Ito, Daisuke, Ivankovic, Davor, Ivanova, Saška, Iyer, Anand Krishnan V., Izquierdo, José M., Izumi, Masanori, Jäättelä, Marja, Jabir, Majid Sakhi, Jackson, William T., Jacobo-Herrera, Nadia, Jacomin, Anne-Claire, Jacquin, Elise, Jadiya, Pooja, Jaeschke, Hartmut, Jagannath, Chinnaswamy, Jakobi, Arjen J., Jakobsson, Johan, Janji, Bassam, Jansen-Dürr, Pidder, Jansson, Patric J., Jantsch, Jonathan, Januszewski, Sławomir, Jassey, Alagie, Jean, Steve, Jeltsch-David, Hélène, Jendelova, Pavla, Jenny, Andreas, Jensen, Thomas E., Jessen, Niels, Jewell, Jenna L., Ji, Jing, Jia, Lijun, Jia, Rui, Jiang, Liwen, Jiang, Qing, Jiang, Richeng, Jiang, Teng, Jiang, Xuejun, Jiang, Yu, Jimenez-Sanchez, Maria, Jin, Eun-Jung, Jin, Fengyan, Jin, Hongchuan, Jin, Li, Jin, Luqi, Jin, Meiyan, Jin, Si, Jo, Eun-Kyeong, Joffre, Carine, Johansen, Terje, Johnson, Gail V.W., Johnston, Simon A., Jokitalo, Eija, Jolly, Mohit Kumar, Joosten, Leo A.B., Jordan, Joaquin, Joseph, Bertrand, Ju, Dianwen, Ju, Jeong-Sun, Ju, Jingfang, Juárez, Esmeralda, Judith, Delphine, Juhász, Gábor, Jun, Youngsoo, Jung, Chang Hwa, Jung, Sung-Chul, Jung, Yong Keun, Jungbluth, Heinz, Jungverdorben, Johannes, Just, Steffen, Kaarniranta, Kai, Kaasik, Allen, Kabuta, Tomohiro, Kaganovich, Daniel, Kahana, Alon, Kain, Renate, Kajimura, Shinjo, Kalamvoki, Maria, Kalia, Manjula, Kalinowski, Danuta S., Kaludercic, Nina, Kalvari, Ioanna, Kaminska, Joanna, Kaminskyy, Vitaliy O., Kanamori, Hiromitsu, Kanasaki, Keizo, Kang, Chanhee, Kang, Rui, Kang, Sang Sun, Kaniyappan, Senthilvelrajan, Kanki, Tomotake, Kanneganti, Thirumala-Devi, Kanthasamy, Anumantha G., Kanthasamy, Arthi, Kantorow, Marc, Kapuy, Orsolya, Karamouzis, Michalis V., Karim, Md. Razaul, Karmakar, Parimal, Katare, Rajesh G., Kato, Masaru, Kaufmann, Stefan H.E., Kauppinen, Anu, Kaushal, Gur P., Kaushik, Susmita, Kawasaki, Kiyoshi, Kazan, Kemal, Ke, Po-Yuan, Keating, Damien J., Keber, Ursula, Kehrl, John H., Keller, Kate E., Keller, Christian W., Kemper, Jongsook Kim, Kenific, Candia M., Kepp, Oliver, Kermorgant, Stephanie, Kern, Andreas, Ketteler, Robin, Keulers, Tom G., Khalfin, Boris, Khalil, Hany, Khambu, Bilon, Khan, Shahid Y., Khandelwal, Vinoth Kumar Megraj, Khandia, Rekha, Kho, Widuri, Khobrekar, Noopur V., Khuansuwan, Sataree, Khundadze, Mukhran, Killackey, Samuel A., Kim, Dasol, Kim, Deok Ryong, Kim, Do-Hyung, Kim, Dong-Eun, Kim, Eun Young, Kim, Eun-Kyoung, Kim, Hak-Rim, Kim, Hee-Sik, Kim, Hyung-Ryong, Kim, Jeong Hun, Kim, Jin Kyung, Kim, Jin-Hoi, Kim, Joungmok, Kim, Ju Hwan, Kim, Keun Il, Kim, Peter K., Kim, Seong-Jun, Kimball, Scot R., Kimchi, Adi, Kimmelman, Alec C., Kimura, Tomonori, King, Matthew A., Kinghorn, Kerri J., Kinsey, Conan G., Kirkin, Vladimir, Kirshenbaum, Lorrie A., Kiselev, Sergey L., Kishi, Shuji, Kitamoto, Katsuhiko, Kitaoka, Yasushi, Kitazato, Kaio, Kitsis, Richard N., Kittler, Josef T., Kjaerulff, Ole, Klein, Peter S., Klopstock, Thomas, Klucken, Jochen, Knævelsrud, Helene, Knorr, Roland L., Ko, Ben C.B., Ko, Fred, Ko, Jiunn-Liang, Kobayashi, Hotaka, Kobayashi, Satoru, Koch, Ina, Koch, Jan C., Koenig, Ulrich, Kögel, Donat, Koh, Young Ho, Koike, Masato, Kohlwein, Sepp D., Kocaturk, Nur M., Komatsu, Masaaki, König, Jeannette, Kono, Toru, Kopp, Benjamin T., Korcsmaros, Tamas, Korkmaz, Gözde, Korolchuk, Viktor I., Korsnes, Mónica Suárez, Koskela, Ali, Kota, Janaiah, Kotake, Yaichiro, Kotler, Monica L., Kou, Yanjun, Koukourakis, Michael I., Koustas, Evangelos, Kovacs, Attila L., Kovács, Tibor, Koya, Daisuke, Kozako, Tomohiro, Kraft, Claudine, Krainc, Dimitri, Krämer, Helmut, Krasnodembskaya, Anna D., Kretz-Remy, Carole, Kroemer, Guido, Ktistakis, Nicholas T., Kuchitsu, Kazuyuki, Kuenen, Sabine, Kuerschner, Lars, Kukar, Thomas, Kumar, Ajay, Kumar, Ashok, Kumar, Deepak, Kumar, Dhiraj, Kumar, Sharad, Kume, Shinji, Kumsta, Caroline, Kundu, Chanakya N., Kundu, Mondira, Kunnumakkara, Ajaikumar B., Kurgan, Lukasz, Kutateladze, Tatiana G., Kutlu, Ozlem, Kwak, SeongAe, Kwon, Ho Jeong, Kwon, Taeg Kyu, Kwon, Yong Tae, Kyrmizi, Irene, La Spada, Albert, Labonté, Patrick, Ladoire, Sylvain, Laface, Ilaria, Lafont, Frank, Lagace, Diane C., Lahiri, Vikramjit, Lai, Zhibing, Laird, Angela S., Lakkaraju, Aparna, Lamark, Trond, Lan, Sheng-Hui, Landajuela, Ane, Lane, Darius J. R., Lane, Jon D., Lang, Charles H., Lange, Carsten, Langel, Ülo, Langer, Rupert, Lapaquette, Pierre, Laporte, Jocelyn, LaRusso, Nicholas F., Lastres-Becker, Isabel, Lau, Wilson Chun Yu, Laurie, Gordon W., Lavandero, Sergio, Law, Betty Yuen Kwan, Law, Helen Ka-wai, Layfield, Rob, Le, Weidong, Le Stunff, Herve, Leary, Alexandre Y., Lebrun, Jean-Jacques, Leck, Lionel Y.W., Leduc-Gaudet, Jean-Philippe, Lee, Changwook, Lee, Chung-Pei, Lee, Da-Hye, Lee, Edward B., Lee, Erinna F., Lee, Gyun Min, Lee, He-Jin, Lee, Heung Kyu, Lee, Jae Man, Lee, Jason S., Lee, Jin-A, Lee, Joo-Yong, Lee, Jun Hee, Lee, Michael, Lee, Min Goo, Lee, Min Jae, Lee, Myung-Shik, Lee, Sang Yoon, Lee, Seung-Jae, Lee, Stella Y., Lee, Sung Bae, Lee, Won Hee, Lee, Ying-Ray, Lee, Yong-ho, Lee, Youngil, Lefebvre, Christophe, Legouis, Renaud, Lei, Yu L., Lei, Yuchen, Leikin, Sergey, Leitinger, Gerd, Lemus, Leticia, Leng, Shuilong, Lenoir, Olivia, Lenz, Guido, Lenz, Heinz Josef, Lenzi, Paola, León, Yolanda, Leopoldino, Andréia M., Leschczyk, Christoph, Leskelä, Stina, Letellier, Elisabeth, Leung, Chi-Ting, Leung, Po Sing, Leventhal, Jeremy S., Levine, Beth, Lewis, Patrick A., Ley, Klaus, Li, Bin, Li, Da-Qiang, Li, Jianming, Li, Jing, Li, Jiong, Li, Ke, Li, Liwu, Li, Mei, Li, Min, Li, Min, Li, Ming, Li, Mingchuan, Li, Pin-Lan, Li, Ming-Qing, Li, Qing, Li, Sheng, Li, Tiangang, Li, Wei, Li, Wenming, Li, Xue, Li, Yi-Ping, Li, Yuan, Li, Zhiqiang, Li, Zhiyong, Li, Zhiyuan, Lian, Jiqin, Liang, Chengyu, Liang, Qiangrong, Liang, Weicheng, Liang, Yongheng, Liang, YongTian, Liao, Guanghong, Liao, Lujian, Liao, Mingzhi, Liao, Yung-Feng, Librizzi, Mariangela, Lie, Pearl P. Y., Lilly, Mary A., Lim, Hyunjung J., Lima, Thania R.R., Limana, Federica, Lin, Chao, Lin, Chih-Wen, Lin, Dar-Shong, Lin, Fu-Cheng, Lin, Jiandie D., Lin, Kurt M., Lin, Kwang-Huei, Lin, Liang-Tzung, Lin, Pei-Hui, Lin, Qiong, Lin, Shaofeng, Lin, Su-Ju, Lin, Wenyu, Lin, Xueying, Lin, Yao-Xin, Lin, Yee-Shin, Linden, Rafael, Lindner, Paula, Ling, Shuo-Chien, Lingor, Paul, Linnemann, Amelia K., Liou, Yih-Cherng, Lipinski, Marta M., Lipovšek, Saška, Lira, Vitor A., Lisiak, Natalia, Liton, Paloma B., Liu, Chao, Liu, Ching-Hsuan, Liu, Chun-Feng, Liu, Cui Hua, Liu, Fang, Liu, Hao, Liu, Hsiao-Sheng, Liu, Hua-feng, Liu, Huifang, Liu, Jia, Liu, Jing, Liu, Julia, Liu, Leyuan, Liu, Longhua, Liu, Meilian, Liu, Qin, Liu, Wei, Liu, Wende, Liu, Xiao-Hong, Liu, Xiaodong, Liu, Xingguo, Liu, Xu, Liu, Xuedong, Liu, Yanfen, Liu, Yang, Liu, Yang, Liu, Yueyang, Liu, Yule, Livingston, J. Andrew, Lizard, Gerard, Lizcano, Jose M., Ljubojevic-Holzer, Senka, LLeonart, Matilde E., Llobet-Navàs, David, Llorente, Alicia, Lo, Chih Hung, Lobato-Márquez, Damián, Long, Qi, Long, Yun Chau, Loos, Ben, Loos, Julia A., López, Manuela G., López-Doménech, Guillermo, López-Guerrero, José Antonio, López-Jiménez, Ana T., López-Pérez, Óscar, López-Valero, Israel, Lorenowicz, Magdalena J., Lorente, Mar, Lorincz, Peter, Lossi, Laura, Lotersztajn, Sophie, Lovat, Penny E., Lovell, Jonathan F., Lovy, Alenka, Lőw, Péter, Lu, Guang, Lu, Haocheng, Lu, Jia-Hong, Lu, Jin-Jian, Lu, Mengji, Lu, Shuyan, Luciani, Alessandro, Lucocq, John M., Ludovico, Paula, Luftig, Micah A., Luhr, Morten, Luis-Ravelo, Diego, Lum, Julian J., Luna-Dulcey, Liany, Lund, Anders H., Lund, Viktor K., Lünemann, Jan D., Lüningschrör, Patrick, Luo, Honglin, Luo, Rongcan, Luo, Shouqing, Luo, Zhi, Luparello, Claudio, Lüscher, Bernhard, Luu, Luan, Lyakhovich, Alex, Lyamzaev, Konstantin G., Lystad, Alf Håkon, Lytvynchuk, Lyubomyr, Ma, Alvin C., Ma, Changle, Ma, Mengxiao, Ma, Ning-Fang, Ma, Quan-Hong, Ma, Xinliang, Ma, Yueyun, Ma, Zhenyi, MacDougald, Ormond A., Macian, Fernando, MacIntosh, Gustavo C., MacKeigan, Jeffrey P., Macleod, Kay F., Maday, Sandra, Madeo, Frank, Madesh, Muniswamy, Madl, Tobias, Madrigal-Matute, Julio, Maeda, Akiko, Maejima, Yasuhiro, Magarinos, Marta, Mahavadi, Poornima, Maiani, Emiliano, Maiese, Kenneth, Maiti, Panchanan, Maiuri, Maria Chiara, Majello, Barbara, Major, Michael B., Makareeva, Elena, Malik, Fayaz, Mallilankaraman, Karthik, Malorni, Walter, Maloyan, Alina, Mammadova, Najiba, Man, Gene Chi Wai, Manai, Federico, Mancias, Joseph D., Mandelkow, Eva-Maria, Mandell, Michael A., Manfredi, Angelo A., Manjili, Masoud H., Manjithaya, Ravi, Manque, Patricio, Manshian, Bella B., Manzano, Raquel, Manzoni, Claudia, Mao, Kai, Marchese, Cinzia, Marchetti, Sandrine, Marconi, Anna Maria, Marcucci, Fabrizio, Mardente, Stefania, Mareninova, Olga A., Margeta, Marta, Mari, Muriel, Marinelli, Sara, Marinelli, Oliviero, Mariño, Guillermo, Mariotto, Sofia, Marshall, Richard S., Marten, Mark R., Martens, Sascha, Martin, Alexandre P.J., Martin, Katie R., Martin, Sara, Martin, Shaun, Martín-Segura, Adrián, Martín-Acebes, Miguel A., Martin-Burriel, Inmaculada, Martin-Rincon, Marcos, Martin-Sanz, Paloma, Martina, José A., Martinet, Wim, Martinez, Aitor, Martinez, Ana, Martinez, Jennifer, Martinez Velazquez, Moises, Martinez-Lopez, Nuria, Martinez-Vicente, Marta, Martins, Daniel O., Martins, Joilson O., Martins, Waleska K., Martins-Marques, Tania, Marzetti, Emanuele, Masaldan, Shashank, Masclaux-Daubresse, Celine, Mashek, Douglas G., Massa, Valentina, Massieu, Lourdes, Masson, Glenn R., Masuelli, Laura, Masyuk, Anatoliy I., Masyuk, Tetyana V., Matarrese, Paola, Matheu, Ander, Matoba, Satoaki, Matsuzaki, Sachiko, Mattar, Pamela, Matte, Alessandro, Mattoscio, Domenico, Mauriz, José L., Mauthe, Mario, Mauvezin, Caroline, Maverakis, Emanual, Maycotte, Paola, Mayer, Johanna, Mazzoccoli, Gianluigi, Mazzoni, Cristina, Mazzulli, Joseph R., McCarty, Nami, McDonald, Christine, McGill, Mitchell R., McKenna, Sharon L., McLaughlin, BethAnn, McLoughlin, Fionn, McNiven, Mark A., McWilliams, Thomas G., Mechta-Grigoriou, Fatima, Medeiros, Tania Catarina, Medina, Diego L., Megeney, Lynn A., Megyeri, Klara, Mehrpour, Maryam, Mehta, Jawahar L., Meijer, Alfred J., Meijer, Annemarie H., Mejlvang, Jakob, Meléndez, Alicia, Melk, Annette, Memisoglu, Gonen, Mendes, Alexandrina F., Meng, Delong, Meng, Fei, Meng, Tian, Menna-Barreto, Rubem, Menon, Manoj B., Mercer, Carol, Mercier, Anne E., Mergny, Jean-Louis, Merighi, Adalberto, Merkley, Seth D., Merla, Giuseppe, Meske, Volker, Mestre, Ana Cecilia, Metur, Shree Padma, Meyer, Christian, Meyer, Hemmo, Mi, Wenyi, Mialet-Perez, Jeanne, Miao, Junying, Micale, Lucia, Miki, Yasuo, Milan, Enrico, Milczarek, Małgorzata, Miller, Dana L., Miller, Samuel I., Miller, Silke, Millward, Steven W., Milosevic, Ira, Minina, Elena A., Mirzaei, Hamed, Mirzaei, Hamid Reza, Mirzaei, Mehdi, Mishra, Amit, Mishra, Nandita, Mishra, Paras Kumar, Misirkic Marjanovic, Maja, Misasi, Roberta, Misra, Amit, Misso, Gabriella, Mitchell, Claire, Mitou, Geraldine, Miura, Tetsuji, Miyamoto, Shigeki, Miyazaki, Makoto, Miyazaki, Mitsunori, Miyazaki, Taiga, Miyazawa, Keisuke, Mizushima, Noboru, Mogensen, Trine H., Mograbi, Baharia, Mohammadinejad, Reza, Mohamud, Yasir, Mohanty, Abhishek, Mohapatra, Sipra, Möhlmann, Torsten, Mohmmed, Asif, Moles, Anna, Moley, Kelle H., Molinari, Maurizio, Mollace, Vincenzo, Møller, Andreas Buch, Mollereau, Bertrand, Mollinedo, Faustino, Montagna, Costanza, Monteiro, Mervyn J., Montella, Andrea, Montes, L. Ruth, Montico, Barbara, Mony, Vinod K., Monzio Compagnoni, Giacomo, Moore, Michael N., Moosavi, Mohammad A., Mora, Ana L., Mora, Marina, Morales-Alamo, David, Moratalla, Rosario, Moreira, Paula I., Morelli, Elena, Moreno, Sandra, Moreno-Blas, Daniel, Moresi, Viviana, Morga, Benjamin, Morgan, Alwena H., Morin, Fabrice, Morishita, Hideaki, Moritz, Orson L., Moriyama, Mariko, Moriyasu, Yuji, Morleo, Manuela, Morselli, Eugenia, Moruno-Manchon, Jose F., Moscat, Jorge, Mostowy, Serge, Motori, Elisa, Moura, Andrea Felinto, Moustaid-Moussa, Naima, Mrakovcic, Maria, Muciño-Hernández, Gabriel, Mukherjee, Anupam, Mukhopadhyay, Subhadip, Mulcahy Levy, Jean M., Mulero, Victoriano, Muller, Sylviane, Münch, Christian, Munjal, Ashok, Munoz-Canoves, Pura, Muñoz-Galdeano, Teresa, Münz, Christian, Murakawa, Tomokazu, Muratori, Claudia, Murphy, Brona M., Murphy, J. Patrick, Murthy, Aditya, Myöhänen, Timo T., Mysorekar, Indira U., Mytych, Jennifer, Nabavi, Seyed Mohammad, Nabissi, Massimo, Nagy, Péter, Nah, Jihoon, Nahimana, Aimable, Nakagawa, Ichiro, Nakamura, Ken, Nakatogawa, Hitoshi, Nandi, Shyam S., Nanjundan, Meera, Nanni, Monica, Napolitano, Gennaro, Nardacci, Roberta, Narita, Masashi, Nassif, Melissa, Nathan, Ilana, Natsumeda, Manabu, Naude, Ryno J., Naumann, Christin, Naveiras, Olaia, Navid, Fatemeh, Nawrocki, Steffan T., Nazarko, Taras Y., Nazio, Francesca, Negoita, Florentina, Neill, Thomas, Neisch, Amanda L., Neri, Luca M., Netea, Mihai G., Neubert, Patrick, Neufeld, Thomas P., Neumann, Dietbert, Neutzner, Albert, Newton, Phillip T., Ney, Paul A., Nezis, Ioannis P., Ng, Charlene C.W., Ng, Tzi Bun, Nguyen, Hang T. T., Nguyen, Long T., Ni, Hong-Min, Ní Cheallaigh, Clíona, Ni, Zhenhong, Nicolao, M. Celeste, Nicoli, Francesco, Nieto-Diaz, Manuel, Nilsson, Per, Ning, Shunbin, Niranjan, Rituraj, Nishimune, Hiroshi, Niso-Santano, Mireia, Nixon, Ralph A., Nobili, Annalisa, Nobrega, Clevio, Noda, Takeshi, Nogueira-Recalde, Uxía, Nolan, Trevor M., Nombela, Ivan, Novak, Ivana, Novoa, Beatriz, Nozawa, Takashi, Nukina, Nobuyuki, Nussbaum-Krammer, Carmen, Nylandsted, Jesper, O’Donovan, Tracey R., O’Leary, Seónadh M., O’Rourke, Eyleen J., O’Sullivan, Mary P., O’Sullivan, Timothy E., Oddo, Salvatore, Oehme, Ina, Ogawa, Michinaga, Ogier-Denis, Eric, Ogmundsdottir, Margret H., Ogretmen, Besim, Oh, Goo Taeg, Oh, Seon-Hee, Oh, Young J., Ohama, Takashi, Ohashi, Yohei, Ohmuraya, Masaki, Oikonomou, Vasileios, Ojha, Rani, Okamoto, Koji, Okazawa, Hitoshi, Oku, Masahide, Oliván, Sara, Oliveira, Jorge M. A., Ollmann, Michael, Olzmann, James A., Omari, Shakib, Omary, M. Bishr, Önal, Gizem, Ondrej, Martin, Ong, Sang-Bing, Ong, Sang-Ging, Onnis, Anna, Orellana, Juan A., Orellana-Muñoz, Sara, Ortega-Villaizan, Maria Del Mar, Ortiz-Gonzalez, Xilma R., Ortona, Elena, Osiewacz, Heinz D., Osman, Abdel-Hamid K., Osta, Rosario, Otegui, Marisa S., Otsu, Kinya, Ott, Christiane, Ottobrini, Luisa, Ou, Jing-hsiung James, Outeiro, Tiago F., Oynebraten, Inger, Ozturk, Melek, Pagès, Gilles, Pahari, Susanta, Pajares, Marta, Pajvani, Utpal B., Pal, Rituraj, Paladino, Simona, Pallet, Nicolas, Palmieri, Michela, Palmisano, Giuseppe, Palumbo, Camilla, Pampaloni, Francesco, Pan, Lifeng, Pan, Qingjun, Pan, Wenliang, Pan, Xin, Panasyuk, Ganna, Pandey, Rahul, Pandey, Udai B., Pandya, Vrajesh, Paneni, Francesco, Pang, Shirley Y., Panzarini, Elisa, Papademetrio, Daniela L., Papaleo, Elena, Papinski, Daniel, Papp, Diana, Park, Eun Chan, Park, Hwan Tae, Park, Ji-Man, Park, Jong-In, Park, Joon Tae, Park, Junsoo, Park, Sang Chul, Park, Sang-Youel, Parola, Abraham H., Parys, Jan B., Pasquier, Adrien, Pasquier, Benoit, Passos, João F., Pastore, Nunzia, Patel, Hemal H., Patschan, Daniel, Pattingre, Sophie, Pedraza-Alva, Gustavo, Pedraza-Chaverri, Jose, Pedrozo, Zully, Pei, Gang, Pei, Jianming, Peled-Zehavi, Hadas, Pellegrini, Joaquín M., Pelletier, Joffrey, Peñalva, Miguel A., Peng, Di, Peng, Ying, Penna, Fabio, Pennuto, Maria, Pentimalli, Francesca, Pereira, Cláudia MF, Pereira, Gustavo J.S., Pereira, Lilian C., Pereira de Almeida, Luis, Perera, Nirma D., Pérez-Lara, Ángel, Perez-Oliva, Ana B., Pérez-Pérez, María Esther, Periyasamy, Palsamy, Perl, Andras, Perrotta, Cristiana, Perrotta, Ida, Pestell, Richard G., Petersen, Morten, Petrache, Irina, Petrovski, Goran, Pfirrmann, Thorsten, Pfister, Astrid S., Philips, Jennifer A., Pi, Huifeng, Picca, Anna, Pickrell, Alicia M., Picot, Sandy, Pierantoni, Giovanna M., Pierdominici, Marina, Pierre, Philippe, Pierrefite-Carle, Valérie, Pierzynowska, Karolina, Pietrocola, Federico, Pietruczuk, Miroslawa, Pignata, Claudio, Pimentel-Muiños, Felipe X., Pinar, Mario, Pinheiro, Roberta O., Pinkas-Kramarski, Ronit, Pinton, Paolo, Pircs, Karolina, Piya, Sujan, Pizzo, Paola, Plantinga, Theo S., Platta, Harald W., Plaza-Zabala, Ainhoa, Plomann, Markus, Plotnikov, Egor Y., Plun-Favreau, Helene, Pluta, Ryszard, Pocock, Roger, Pöggeler, Stefanie, Pohl, Christian, Poirot, Marc, Poletti, Angelo, Ponpuak, Marisa, Popelka, Hana, Popova, Blagovesta, Porta, Helena, Porte Alcon, Soledad, Portilla-Fernandez, Eliana, Post, Martin, Potts, Malia B., Poulton, Joanna, Powers, Ted, Prahlad, Veena, Prajsnar, Tomasz K., Praticò, Domenico, Prencipe, Rosaria, Priault, Muriel, Proikas-Cezanne, Tassula, Promponas, Vasilis J., Proud, Christopher G., Puertollano, Rosa, Puglielli, Luigi, Pulinilkunnil, Thomas, Puri, Deepika, Puri, Rajat, Puyal, Julien, Qi, Xiaopeng, Qi, Yongmei, Qian, Wenbin, Qiang, Lei, Qiu, Yu, Quadrilatero, Joe, Quarleri, Jorge, Raben, Nina, Rabinowich, Hannah, Ragona, Debora, Ragusa, Michael J., Rahimi, Nader, Rahmati, Marveh, Raia, Valeria, Raimundo, Nuno, Rajasekaran, Namakkal-Soorappan, Ramachandra Rao, Sriganesh, Rami, Abdelhaq, Ramírez-Pardo, Ignacio, Ramsden, David B., Randow, Felix, Rangarajan, Pundi N., Ranieri, Danilo, Rao, Hai, Rao, Lang, Rao, Rekha, Rathore, Sumit, Ratnayaka, J. Arjuna, Ratovitski, Edward A., Ravanan, Palaniyandi, Ravegnini, Gloria, Ray, Swapan K., Razani, Babak, Rebecca, Vito, Reggiori, Fulvio, Régnier-Vigouroux, Anne, Reichert, Andreas S., Reigada, David, Reiling, Jan H., Rein, Theo, Reipert, Siegfried, Rekha, Rokeya Sultana, Ren, Hongmei, Ren, Jun, Ren, Weichao, Renault, Tristan, Renga, Giorgia, Reue, Karen, Rewitz, Kim, Ribeiro de Andrade Ramos, Bruna, Riazuddin, S. Amer, Ribeiro-Rodrigues, Teresa M., Ricci, Jean-Ehrland, Ricci, Romeo, Riccio, Victoria, Richardson, Des R., Rikihisa, Yasuko, Risbud, Makarand V., Risueño, Ruth M., Ritis, Konstantinos, Rizza, Salvatore, Rizzuto, Rosario, Roberts, Helen C., Roberts, Luke D., Robinson, Katherine J., Roccheri, Maria Carmela, Rocchi, Stephane, Rodney, George G., Rodrigues, Tiago, Rodrigues Silva, Vagner Ramon, Rodriguez, Amaia, Rodriguez-Barrueco, Ruth, Rodriguez-Henche, Nieves, Rodriguez-Rocha, Humberto, Roelofs, Jeroen, Rogers, Robert S., Rogov, Vladimir V., Rojo, Ana I., Rolka, Krzysztof, Romanello, Vanina, Romani, Luigina, Romano, Alessandra, Romano, Patricia S., Romeo-Guitart, David, Romero, Luis C., Romero, Montserrat, Roney, Joseph C., Rongo, Christopher, Roperto, Sante, Rosenfeldt, Mathias T., Rosenstiel, Philip, Rosenwald, Anne G., Roth, Kevin A., Roth, Lynn, Roth, Steven, Rouschop, Kasper M.A., Roussel, Benoit D., Roux, Sophie, Rovere-Querini, Patrizia, Roy, Ajit, Rozieres, Aurore, Ruano, Diego, Rubinsztein, David C., Rubtsova, Maria P., Ruckdeschel, Klaus, Ruckenstuhl, Christoph, Rudolf, Emil, Rudolf, Rüdiger, Ruggieri, Alessandra, Ruparelia, Avnika Ashok, Rusmini, Paola, Russell, Ryan R., Russo, Gian Luigi, Russo, Maria, Russo, Rossella, Ryabaya, Oxana O., Ryan, Kevin M., Ryu, Kwon-Yul, Sabater-Arcis, Maria, Sachdev, Ulka, Sacher, Michael, Sachse, Carsten, Sadhu, Abhishek, Sadoshima, Junichi, Safren, Nathaniel, Saftig, Paul, Sagona, Antonia P., Sahay, Gaurav, Sahebkar, Amirhossein, Sahin, Mustafa, Sahin, Ozgur, Sahni, Sumit, Saito, Nayuta, Saito, Shigeru, Saito, Tsunenori, Sakai, Ryohei, Sakai, Yasuyoshi, Sakamaki, Jun-Ichi, Saksela, Kalle, Salazar, Gloria, Salazar-Degracia, Anna, Salekdeh, Ghasem H., Saluja, Ashok K., Sampaio-Marques, Belém, Sanchez, Maria Cecilia, Sanchez-Alcazar, Jose A., Sanchez-Vera, Victoria, Sancho-Shimizu, Vanessa, Sanderson, J. 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Charlie, Kenchappa, Chandra Shekar, Li, Zuguo, Lin, Yong, Oshima, Shigeru, Rong, Yueguang, Sluimer, Judith C., Stallings, Christina L., and Tong, Chun-Kit
- Abstract
ABSTRACTIn 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fideautophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.
- Published
- 2021
- Full Text
- View/download PDF
50. Investigation of Immobilization Effects on Ni(P2N2)2Electrocatalysts
- Author
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Brunner, Felix M., Neville, Michael L., and Kubiak, Clifford P.
- Abstract
A new synthetic route to complexes of the type Ni(P2N2)22+with highly functionalized phosphine substituents and the investigation of immobilization effects on these catalysts is reported. Ni(P2N2)22+complexes have been extensively studied as homogeneous and surface-attached molecular electrocatalysts for the hydrogen evolution reaction (HER). A synthesis based on postsynthetic modification of PArBr2NPh2was developed and is described here. Phosphonate-modified ligands and their corresponding nickel complexes were isolated and characterized. Subsequent deprotection of the phosphonic ester derivatives provided the first Ni(P2N2)22+catalyst that can be covalently attached via pendent phosphonate groups to an electrode without involvement of the important pendent amine groups. Mesoporous TiO2electrodes were surface modified by attachment of the new phosphonate functionalized Ni(P2N2)22+complexes, and these provided electrocatalytic materials that proved to be competent and stable for sustained HER in aqueous solution at mild pH and low overpotential. We directly compared the new ligand to a previously reported complex that utilized the amine moiety for surface attachment. Using HER as the benchmark reaction, the P-attached catalyst showed a marginally (9–14%) higher turnover number than its N-attached counterpart.
- Published
- 2020
- Full Text
- View/download PDF
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