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The rise of artificial intelligence in healthcare, particularly the development of large language models like ChatGPT, has opened new avenues for innovation in medical fields, including plastic surgery. ChatGPT offers potential applications in patient education, surgical planning, and decision-making support, making it an important research subject. However, there has been limited investigation into its impact on plastic surgery. The objective of this study was to investigate the progress of research on ChatGPT and plastic surgery, focusing on key contributors and emerging topics within the field.

Background and Purpose In the present work, chitosan is furnished with tin dioxide (CsSnO2) nanoparticles (NPs) synthesized using the green route using Moringa oleifera(M. oleifera) flower extract.Methods These preparation methods are low-cost, easily reproducible, nontoxic, and eco-friendly. X-ray diffraction (XRD), dynamic light scattering (DLS), field emission scanning electron microscope (FESEM), energy dispersive X-ray, Fourier-transform infrared spectroscopy (FT-IR), and photoluminescence (PL) analysis were used to learn more about the CsSnO2NPs. The antibacterial property of CsSnO2NPs was assessed by the disc diffusion method against various pathogens. The MTT assay was done to assess the cytotoxicity of CsSnO2NPs in MCF-7 cells. The expressions of the apoptotic proteins were examined using assay kits.Results XRD results demonstrated that the formulated CsSnO2NPs exhibit a tetragonal structure. From the FT-IR spectra, the Sn–O stretching peak was observed at 579 cm–1. A FESEM image shows that the CsSnO2NPs were formed into a spherical structure. Surface defects, such as tin and oxygen vacancies, are visible in the PL spectra, and the average particle size of CsSnO2NPs is 32 nm. Thus, surface defects are essential parameters for biocidal properties. The antimicrobial property of CsSnO2NPs and amoxicillin was investigated against bacteria and human fungal pathogens. CsSnO2NPs exhibit similar antimicrobial properties as compared to amoxicillin. Also, the dosage of CsSnO2NPs elevated their antimicrobial activity. The anticancer property of the green-synthesized CsSnO2NPs against MCF-7 cells was further analyzed to study their ability to cytotoxicity and apoptosis induction, like caspase-3, -8, and -9 activation.Conclusion The study’s outcome revealed that the green synthesized CsSnO2NPs are an outstanding candidate for cancer therapy.

A high increase witnessed in type II diabetes mellitus (T2DM) globally has increasingly posed a serious threat to global increases in liver cancer with the association between diabetes mellitus type II and the survival rate in liver cancer patients showing unstable findings. An increase in the development and progression of chronic liver disease from diabetes mellitus patients may be connected to cancer of the liver with several links such as Hepatitis B and C virus and heavy consumption of alcohol. The link between T2DM patients and liver cancer is centered on non-alcoholic fatty liver disease (NAFLD) which could be a serious threat globally if not clinically addressed. Several reports identified metformin treatment as linked to a lower risk of liver cancer prognosis while insulin treatment or sulphonylureas posed a serious threat. Mechanistically, the biological linkage between diabetes type II mellitus and liver cancer are still complex to understand with only the existence of a relationship between NAFLD and high level of energy intake and diabetes mellitus induces hepatic damage, increased liver weight thereby causes multiple pro-inflammatory cytokines that lead to the development of liver cancer. Therefore, this review gives an account of the pathophysiological importance of liver cancer position with T2DM, with the role of NAFLD as an important factor that bridges them.