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PAHPN is a new mitochondria targeted probe for in two-photon imaging.

Two is more than one: A method has been developed in which a DNA template triggers a Wittig reaction that leads to transfer of a benzylidene group from a DNA‐linked phosphonium salt to a DNA‐linked benzaldehyde. A synthetic receptor such as α‐cyclodextrin then encapsulates the newly formed stilbene and triggers further signal increases.

The article focuses on a study conducted by researchers at Macquarie University on synthesis of fluorophores which has improved photo-physical properties, low photo bleaching and improved quantum yields unlike the epicocconone fluorescent dye that were low in quantum yields.