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1. Intratumoral heterogeneity after targeted therapy in murine cancer models with differing degrees of malignancy

Author

Gerwing, M., Hoffmann, E., Geyer, C., Helfen, A., Maus, B., Schinner, R., Wachsmuth, L., Heindel, W., Eisenblaetter, M., Faber, C., and Wildgruber, M.

Abstract

•Volumetric tumor response assessment to targeted therapies is insufficient.•mp MRI enables assessment of therapy-induced changes of the tumor microenvironment.•Treatment response differs between tumor models with diverging grades of malignancy.•Different treatment approaches lead to an increase in intratumoral heterogeneity.

Published
2023
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