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2. The role of science in improving government accountability to society.

Author

Marin, L. E., Ramirez, E. Sanchez, and Martinez, V.

Subjects
*SCIENCE & state, *POLITICAL accountability, *WATER supply policy, *SCIENCE & society
Abstract

The water governance elements for Mexico are presented, using the trialogue model. Three examples of water governance for Aguascalientes. Guerrero and the Yucatan are given. In all three cases, there is a strong presence of the federal government. In two cases, where there is a stronger science or society element, there is improved water governance. Activities of the Water Network of the Mexican Academy of Sciences, that are enhancing the science society, and science government interfaces are presented. This paper shows how a group of scientists are trying to improve the water governance in Mexico through the development of stronger interfaces between science and society so that, eventually, a better informed society may hold its policy-makers accountable. [ABSTRACT FROM AUTHOR]

Published
2007
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3. Pseudo-reflection phenomena for singularities in thin elastic shells

Author

Karamian-Surville, P., Sanchez-Hubert, J., and Palencia, E. Sanchez

Abstract

We consider problems of statics of thin elastic shells with hyperbolic middle surface subjected to boundary conditions ensuring the geometric rigidity of the surface. The asymptotic behaviour of the solutions when the relative thickness tends to zero is then given by the membrane approximation. It is a hyperbolic problem propagating singularities along the characteristics. We address here the reflection phenomena when the propagated singularities arrive to a boundary. As the boundary conditions are not the classical ones for a hyperbolic system, there are various cases of reflection. Roughly speaking, singularities provoked elsewhere are not reflected at all at a free boundary, whereas at a fixed (or clamped) boundary the reflected singularity is less singular than the incident one. Reflection of singularities provoked along a non-characteristic curve C are also considered. Copyright © 2003 John Wiley & Sons, Ltd.

Published
2003
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4. Analysis of the Opposite Solvent Effects Caused by Different Solute Cavities on the Metal−Water Distance of Monoatomic Cation Hydrates

Author

Martinez, J. M., Pappalardo, R. R., Marcos, E. Sanchez, Mennucci, B., and Tomasi, J.

Abstract

Theoretical studies on metal cations in water have lead to a controversy regarding the distance between the cation and the oxygen nuclei of the first solvation shell. Apparently this is due to the differences in the description of solvent effects which can lead to opposite conclusions:  a shortening or a lengthening of this distance in the bulk solution with respect to that found in the hydrated cation in a vacuum. This discrepancy has been attributed to the difference between discrete and continuum solvation models. Likewise, within the continuum model, two widely used methods, those of the multipole expansion (MPE), from the Nancy group (using a spherical cavity), and the polarized continuum model (PCM) from the Pisa group (using a molecularly shaped cavity), have given different results. This work reconsiders the solvent effects on the geometry of a set of hydrated cations ([M(H2O)m]n+, where M = Be2+, Mg2+, Ca2+, Zn2+, and Al3+) by comparing results derived from a previous work [J. Phys. Chem. 1991, 95, 8928] using the MPE approach with new PCM calculations. It is shown that both methods lead to the same results when the same (spherical) cavity is used, but PCM results, with molecularly shaped cavities, are in better agreement with those obtained with discrete solvent models. A continuous change in the atomic parameters defining the cavity allows the transition from one cavity shape to another and to observe the reversal in the prediction of the change in the M−O distances. The present study shows the substantial equivalence of the two methods (never accurately checked in precedence) and reveals that the M−O distance in the first hydration shell is an appropriate parameter to monitor finer aspects of the solute−solvent interactions, related to the discreteness of the solvent interactions in the second shell. These effects can be reproduced at a very good extent by continuum models with molecularly shaped cavities.

Published
2002

9. X-ray Absorption Spectroscopy Study of the In-Solution Structure of Ni<SUP>2+</SUP>, Co<SUP>2+</SUP>, and Ag<SUP>+</SUP> Solvates in Acetonitrile Including Multiple Scattering Contributions

Author

Diaz-Moreno, S., Munoz-Paez, A., and Marcos, E. Sanchez

Abstract

An X-ray absorption spectroscopy study of the in-solution structures of the acetonitrile solvates of Ni2+, Co2+ and Ag+ cations has been performed. For the first two cations an octahedral arrangement of the acetonitrile molecules around the central metal atom has been found, while in the case of the Ag+ a tetrahedral arrangement has been found. In all cases the acetonitrile molecules were bonded to the central cation through the nitrogen atom at distances R(Co2+−N) = 2.11 Å, R(Ni2+−N) 2.07 Å, R(Ag+−N) = 2.27 Å. The unusual high amplitude of the second peak in the radial distribution function, corresponding to the carbon atom of the cyanide group, for the three studied solvates, indicated that the angle formed by M−N−C was very close to 180°. The quantitative analysis of the most intense multiple scattering contributions among those involving N atoms, C atoms from the cyanide group and C atoms form the methyl group provided values of Mn+−C1 and Mn+−C2 coordination distances as well as an estimate of coordination angles.

Published
2000

11. Theoretical Study of the Microsolvation of the Bromide Anion in Water, Methanol, and Acetonitrile:  Ion−Solvent vs Solvent−Solvent Interactions

Author

Ayala, R., Martinez, J. M., Pappalardo, R. R., and Marcos, E. Sanchez

Abstract

In this paper a theoretical study of the bromide solvation in three different polar solvents is presented:  water, methanol, and acetonitrile. DFT (B3LYP) calculations on the structure and energetics of [Br(Solv)n]- clusters, for n = 1−9 and Solv = H2O, CH3OH, and CH3CN, have been carried out. Different structures where the anion is placed inside or on the surface of the cluster have been explored. The relative importance of solvent−solvent vs ion−solvent interactions determines the geometrical distribution of the microsolvation. Aggregates of solvent molecules within the bromide clusters are more defined in the case of water. Methanolated bromide clusters show a defined trend to place some solvent molecule at the second solvation shell. The bigger acetonitrile complexes (n > 5) are the more representative cases of interior complexes where the solvent molecules surround quite symmetrically the bromide anion whereas, in water and methanol, the microsolvation is more compromised between bromide−solvent and solvent−solvent interactions, then favoring arrangements with the ion on the surface of the cluster, particularly for n &lt; 5. To rationalize the key components of the microsolvation, ion−solvent and solvent−solvent interaction energies have been decomposed in terms of two-body, three-body, and four-body contributions. Three-body terms are important for methanol and acetonitrile clusters due to the bromide−solvent contribution, whereas for aqueous clusters a significant cancellation between bromide−water and water−water interactions largely reduces the total three-body component.

Published
2000

12. Kinetic Modeling of Methanol Transformation into Olefins on a SAPO-34 Catalyst

Author

Gayubo, A. G., Aguayo, A. T., Campo, A. E. Sanchez del, Tarrio, A. M., and Bilbao, J.

Abstract

A kinetic model for the methanol to olefins (MTO) process on a catalyst based on a silicoaluminophosphate SAPO-34 has been proposed. The model takes into account four individual steps for the production of ethene, propene, butenes, and remaining hydrocarbons (pentenes + paraffins). The kinetic parameters have been obtained by experimentation in an isothermal fixed-bed reactor, in the 623−748 K range. In virtue of the results, it has been proven that the water introduced in the feed (required for attenuation of coke deactivation) inhibits olefin formation. This inhibition is taken into account in the kinetic model.

Published
2000

19. Oxidation channel: A method for domestic sewage treatment in Cuba

Author

Cordoba, L. Travieso, Echegoyen, F. Benitez, Lau-Si, M. Leon, and Hernandez, E. Sanchez

Abstract

Different methods have been used suscessfully for the removal of organic matter in wastewaters. Conventional treatments are frequently used in Cuba. However, the Oxidation Channel, constitutes a very simple aerobic treatment and it has been never used in Cuba.This paper presents an evaluation of the behaviour of this biological reactor in Cuban climatic conditions.Conventional parameters for wastewaters were determined and the obtaining results were promising.

Published
1990
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20. Structure theorem for prime rings satisfying a generalized identity

Author

Lopez, A. Fernandez, Rus, E. Garcia, and Campos, E. Sanchez

Abstract

We prove in this paper a structure theorem for prime rings whose symmetric ring of quotients has nonzero socle. Then this result is applied to prime rings satisfying a generalized identity, and to prime rings having an alternate involution.

Published
1994
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21. Los medios de difusion masiva y la centralizacion en Mexico

Author

Ruiz, Enrique E. Sanchez

Abstract

From a theoretical viewpoint that seeks to comprehend centralization as a system of power, the article traces the origins of the centralized system of media in Mexico and its relation to political, economic and cultural centralization. It provides a picture of the current centralization of media in Mexico.

Published
1988
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23. Acidity, Surface Species, and Mechanism of Methanol Transformation into Olefins on a SAPO-34

Author

Campo, A. E. Sanchez del, Gayubo, A. G., Aguayo, A. T., Tarrio, A., and Bilbao, J.

Abstract

The nature of the active sites and the distribution of acidity strength of a SAPO-34 silicoaluminophosphate has been studied by FTIR spectrophotometry and by combined calorimetry-gas chromatography of ammonia desorption. On the basis of the in situ FTIR analysis of the surface species generated in the transformation of methanol into olefins and of the evidence of the existence of oxonium ions as intermediates, a mechanism has been proposed for the reaction, in which the oxonium ions are successively methylized by means of propagation reactions in the solid phase and ethyloxonium, propyloxonium, and so forth, are formed. This mechanism is mainly conditioned by shape selectivity.

Published
1998

24. Increased Serum ß2-Microglobulin Levels in Active Celiac Disease

Author

Blanco, A., Alonso, M., Cilleruelo, M. L., Solis, P., Calvo, C., and Villares, E. Sanchez

Abstract

Sixty-eight sera from 36 children with celiac disease (CD) were collected in a 4-year study, and the levels of ß2-microglobulin (ß2M), orosomucoid, a1-antitrypsin, and C-reactive protein (CRP) were measured. A simultaneous intestinal biopsy was taken in all the patients and used to classify them. The values of (ß2M were 1.94 ± 0.49 mg/L in group A (inactive CD with normal intestinal biopsy) and 2.58 ± 0.76 mg/L in group B (active CD with flat mucosa). These levels were higher than in the normal controls (1.87 ± 0.49 mg/L, p < 0.005) and in the other 19 patients with chronic diarrhea of another cause (1.72 ± 0.63 mg/L, p < 0.005). CRP values were generally normal; orosomucoid and a-antitrypsin were variable and they did not correlate with ß2M levels. ß2M was increased at the time of diagnosis in seven of eight (87.5%) of the CD children and only in three of 19 (15.7%) of nonceliac patients with chronic diarrhea of another cause (p < 0.005). In 12 children with CD, serial studies were possible. The highest ß2M level coincided with a flat mucosa in 10 cases. The increase of ß2M could be related to the intestinal infiltration or even to the lymphocyte activation. It may also be a useful noninvasive method for evaluating the activity of CD.

Published
1985
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26. Increased Serum β2-Microglobulin Levels in Active Celiac Disease

Author

Blanco, A., Alonso, M., Cilleruelo, M. L., Solis, P., Calvo, C., and Villares, E. Sanchez

Abstract

Sixty-eight sera from 36 children with celiac disease (CD) were collected in a 4-year study, and the levels of β2-microglobulin (β2M), orosomucoid, α1-antitrypsin, and C-reactive protein (CRP) were measured. A simultaneous intestinal biopsy was taken in all the patients and used to classify them. The values of (β2M were 1.94 ± 0.49 mg/L in group A (inactive CD with normal intestinal biopsy) and 2.58 ± 0.76 mg/L in group B (active CD with flat mucosa). These levels were higher than in the normal controls (1.87 ± 0.49 mg/L, p < 0.005) and in the other 19 patients with chronic diarrhea of another cause (1.72 ± 0.63 mg/L, p < 0.005). CRP values were generally normal; orosomucoid and α-antitrypsin were variable and they did not correlate with β2M levels. β2M was increased at the time of diagnosis in seven of eight (87.5) of the CD children and only in three of 19 (15.7) of nonceliac patients with chronic diarrhea of another cause (p < 0.005). In 12 children with CD, serial studies were possible. The highest β2M level coincided with a flat mucosa in 10 cases. The increase of β2M could be related to the intestinal infiltration or even to the lymphocyte activation. It may also be a useful noninvasive method for evaluating the activity of CD.

Published
1985

27. Open data from the first and second observing runs of Advanced LIGO and Advanced Virgo

Author

Rich Abbott, Thomas D. Abbott, Sheelu Abraham, Fausto Acernese, Kendall Ackley, Carl Adams, Rana X. Adhikari, Vaishali B. Adya, Christoph Affeldt, Michalis Agathos, Kazuhiro Agatsuma, Nancy Aggarwal, Odylio D. Aguiar, Amit Aich, Lorenzo Aiello, Anirban Ain, Ajith Parameswaran, Gabrielle Allen, Annalisa Allocca, Paul A. Altin, Alex Amato, Shreya Anand, Alena Ananyeva, Stuart B. Anderson, Warren G. Anderson, Svetoslava V. Angelova, Stefano Ansoldi, Sarah Antier, Stephen Appert, Koji Arai, Melody C. Araya, Joseph S. Areeda, Marc Arène, Nicolas Arnaud, Scott M. Aronson, Kg G. Arun, Stefano Ascenzi, Gregory Ashton, Stuart M. Aston, Pia Astone, Florian Aubin, Peter Aufmuth, Kellie AultONeal, Corey Austin, Valerie Avendano, Stanislav Babak, Philippe Bacon, Francesca Badaracco, Maria K.M. Bader, Sangwook Bae, Anne M. Baer, Jonathon Baird, Francesca Baldaccini, Giulio Ballardin, Stefan W. Ballmer, Anna-marie Bals, Alexander Balsamo, Gregory Baltus, Sharan Banagiri, Deepak Bankar, Rameshwar S. Bankar, Juan C. Barayoga, Claudio Barbieri, Barry C. Barish, David Barker, Kevin Barkett, Pablo Barneo, Fabrizio Barone, Bryan Barr, Lisa Barsotti, Matteo Barsuglia, Daniel Barta, Jeffrey Bartlett, Imre Bartos, Riccardo Bassiri, Andrea Basti, Mateusz Bawaj, Joseph C. Bayley, Marco Bazzan, Bence Bécsy, Michal Bejger, Imene Belahcene, Angus S. Bell, Deeksha Beniwal, Michael G. Benjamin, Joe D. Bentley, Fabio Bergamin, Beverly K. Berger, Gerald Bergmann, Sebastiano Bernuzzi, Christopher P.L. Berry, Diego Bersanetti, Alessandro Bertolini, Joseph Betzwieser, Rohan Bhandare, Ankit V. Bhandari, Jeffrey Bidler, Edward Biggs, Igor A. Bilenko, Garilynn Billingsley, Ross Birney, Ofek Birnholtz, Sebastien Biscans, Matteo Bischi, Sylvia Biscoveanu, Aparna Bisht, Guldauren Bissenbayeva, Massimiliano Bitossi, Marieanne A. Bizouard, Kent K. Blackburn, Jonathan Blackman, Carl D. Blair, David G. Blair, Ryan M. Blair, Fabrizio Bobba, Nina Bode, Michel Boer, Yannick Boetzel, Gilles Bogaert, Francois Bondu, Edgard Bonilla, Romain Bonnand, Phillip Booker, Boris A. Boom, Rolf Bork, Valerio Boschi, Sukanta Bose, Vladimir Bossilkov, Joel Bosveld, Yann Bouffanais, Antonella Bozzi, Carlo Bradaschia, Patrick R. Brady, Alyssa Bramley, Marica Branchesi, Jim E. Brau, Matteo Breschi, Tristan Briant, Joseph H. Briggs, Francesco Brighenti, Alain Brillet, Marc Brinkmann, Patrick Brockill, Aidan F. Brooks, Jonathan Brooks, Daniel D. Brown, Sharon Brunett, Giacomo Bruno, Robert Bruntz, Aaron Buikema, Tomasz Bulik, Henk J. Bulten, Alessandra Buonanno, Damir Buskulic, Robert L. Byer, Miriam Cabero, Laura Cadonati, Giampietro Cagnoli, Craig Cahillane, Juan Calderón Bustillo, Jack D. Callaghan, Thomas A. Callister, Enrico Calloni, Jordan B. Camp, Maurizio Canepa, Kipp C. Cannon, Huy-tuong Cao, Junwei Cao, Giovanni Carapella, Franco Carbognani, Santiago Caride, Matthew F. Carney, Gregorio Carullo, Julia Casanueva Diaz, Claudio Casentini, Javier Castañeda, Sarah Caudill, Marco Cavaglià, Fabien Cavalier, Roberto Cavalieri, Giancarlo Cella, Pablo Cerdá-Durán, Elisabetta Cesarini, Oualid Chaibi, Kabir Chakravarti, Chiwai Chan, Manleong Chan, Shiuh Chao, Philip Charlton, Eve A. Chase, Eric Chassande-Mottin, Deep Chatterjee, Mayank Chaturvedi, Hsin-yu Y. Chen, Xu Chen, Yanbei Chen, Hai-ping Cheng, Chi-kit K. Cheong, Hanyu Y. Chia, Francesco Chiadini, Roberto Chierici, Andrea Chincarini, Antonino Chiummo, Gihyuk Cho, Heesuk S. Cho, Min-a Cho, Nelson Christensen, Qi Chu, Sheon Chua, Ka-wai W. Chung, Shinkee Chung, Giacomo Ciani, Pawel Ciecielag, Marek Cieślar, Alexei A. Ciobanu, Riccardo Ciolfi, Francesco Cipriano, Alessio Cirone, Filiberto Clara, James A. Clark, Patrick Clearwater, Sebastien Clesse, Frederic Cleva, Eugenio Coccia, Pierre-francois Cohadon, David Cohen, Marta Colleoni, Christophe G. Collette, Christopher Collins, Monica Colpi, Marcio Constancio Jr., Livia Conti, Sam J. Cooper, Paul Corban, Thomas R. Corbitt, Isabel Cordero-Carrión, Silvia Corezzi, Kenneth R. Corley, Neil Cornish, David Corre, Alessandra Corsi, Stefano Cortese, Cesar A. Costa, Roberto Cotesta, Michael W. Coughlin, Scott B. Coughlin, Jeanpierre Coulon, Stefan T. Countryman, Peter Couvares, Pep B. Covas, David M. Coward, Matthew J. Cowart, Dennis C. Coyne, Robert Coyne, Jolien D. E. Creighton, Teviet D. Creighton, Jonathan Cripe, Michael Croquette, Sgwynne G. Crowder, Jean-rene Cudell, Torrey J. Cullen, Alan Cumming, Rebecca Cummings, Liam Cunningham, Elena Cuoco, Malgorzata Curylo, Tito Dal Canton, Gergely Dálya, Aykutlu Dana, Lara M. Daneshgaran-Bajastani, Beatrice D’Angelo, Stefan L. Danilishin, Sabrina D’Antonio, Karsten Danzmann, Christian Darsow-Fromm, Arnab Dasgupta, Laurence E. H. Datrier, Vincenzo Dattilo, Ishant Dave, Michel Davier, Gareth S. Davies, Derek Davis, Edward J. Daw, Dan DeBra, Malathi Deenadayalan, Jerome Degallaix, Martina De Laurentis, Samuel Deléglise, Matthew Delfavero, Nicola De Lillo, Walter Del Pozzo, Lindsay M. DeMarchi, Virginia D’Emilio, Nicholas Demos, Thomas Dent, Roberto De Pietri, Rosario De Rosa, Camilla De Rossi, Riccardo DeSalvo, Omar de Varona, Sanjeev Dhurandhar, Mario C. Díaz, Mauricio Diaz-Ortiz Jr., Tim Dietrich, Luciano Di Fiore, Chiara Di Fronzo, Cinzia Di Giorgio, Fabrizio Di Giovanni, Matteo Di Giovanni, Tristano Di Girolamo, Alberto Di Lieto, Binlei Ding, Sibilla Di Pace, Irene Di Palma, Francesco Di Renzo, Atul K. Divakarla, Artemiy Dmitriev, Zoheyr Doctor, Fred Donovan, Katherine L. Dooley, Suresh Doravari, Iain Dorrington, Thomas P. Downes, Marco Drago, Jenne C. Driggers, Zhihui Du, Jean-gregoire Ducoin, Peter Dupej, Ofelia Durante, Domenico D’Urso, Sheila E. Dwyer, Paul J. Easter, Graeme Eddolls, Bruce Edelman, Tega B. Edo, Oliver Edy, Anamaria Effler, Phil Ehrens, Johannes Eichholz, Stephen S. Eikenberry, Marc Eisenmann, Robert A. Eisenstein, Aldo Ejlli, Lucianolucianikerrico Errico, Reed C. Essick, Hector Estelles, Dimitri Estevez, Zachariah B. Etienne, Todd Etzel, Matthew Evans, Tom M. Evans, Rebecca E. Ewing, Viviana Fafone, Stephen Fairhurst, Xilong Fan, Stefania Farinon, Benjamin Farr, Will M. Farr, Edward J. Fauchon-Jones, Marc Favata, Maxime Fays, Mariana Fazio, Jon Feicht, Martin M. Fejer, Fangchen Feng, Edit Fenyvesi, Deborah L. Ferguson, Alvaro Fernandez-Galiana, Isidoro Ferrante, Elvis C. Ferreira, Tabata A. Ferreira, Francesco Fidecaro, Irene Fiori, Donatella Fiorucci, Maya Fishbach, Ryan P. Fisher, Rosalba Fittipaldi, Margot Fitz-Axen, Vincenzo Fiumara, Raffaele Flaminio, Erik Floden, Eric Flynn, Heather Fong, Antonio A. Font, Perry Forsyth, Jean-daniel Fournier, Sergio Frasca, Franco Frasconi, Zsolt Frei, Andreas Freise, Raymond Frey, Valentin Frey, Peter Fritschel, Valery V. Frolov, Gabriele Fronzè, Paul Fulda, Michael Fyffe, Hunter A. Gabbard, Bhooshan U. Gadre, Sebastian M. Gaebel, Jonathan R. Gair, Shanika Galaudage, Dhruva Ganapathy, Sharad G. Gaonkar, Cecilio García-Quirós, Fabio Garufi, Bubba Gateley, Sergio Gaudio, Gayathri Gayathri, Gianluca Gemme, Eric Genin, Alberto Gennai, Daniel George, Jogy George, Laszlo Gergely, Sudarshan Ghonge, Abhirup Ghosh, Archisman Ghosh, Shaon Ghosh, Bruno Giacomazzo, Joe A. Giaime, Dwayne D. Giardina, Des R. Gibson, Chalisa Gier, Kiranjyot Gill, Jane Glanzer, Jan Gniesmer, Patrick Godwin, Evan Goetz, Ryan Goetz, Niklas Gohlke, Boris Goncharov, Gabriela González, Gopakumar Gopakumar, Sarah E. Gossan, Matthieu Gosselin, Romain Gouaty, Benjamin Grace, Aniello Grado, Massimo Granata, Alastair Grant, Slawomir Gras, Philippe Grassia, Corey Gray, Rachel Gray, Giuseppe Greco, Anna C. Green, Rhys Green, Elizabeth M. Gretarsson, Hannah L. Griggs, G. Grignani, Andrea Grimaldi, Stefan J. Grimm, Hartmut Grote, Steffen Grunewald, Pierre Gruning, Gianluca M. Guidi, Andre R. Guimaraes, Gerard Guixé, Hitesh K. Gulati, Yuefan Guo, Anuradha Gupta, Anchal Gupta, Pawan Gupta, Eric K. Gustafson, Dick Gustafson, Leila Haegel, Odysse Halim, Evan D. Hall, Eleanor Z. Hamilton, Giles Hammond, Maria Haney, Manuela M. Hanke, Jonathan Hanks, Chad Hanna, Mark D. Hannam, Otto A. Hannuksela, Travis J. Hansen, Joe Hanson, Thomas Harder, Terra Hardwick, Haris Haris, Jan Harms, Gregg M. Harry, Ian W. Harry, Raine K. Hasskew, Carl-johan Haster, Karen Haughian, Fergus J. Hayes, James Healy, Antoine Heidmann, Matthew C. Heintze, Joscha Heinze, Henrich Heitmann, Frances Hellman, Patrice Hello, Gary Hemming, Martin Hendry, Siong S. Heng, Eric Hennes, Jan-simon Hennig, Michele Heurs, Stefan Hild, Tanja Hinderer, Sarah Y. Hoback, Sven Hochheim, Elyssa Hofgard, David Hofman, Aaron M. Holgado, Nathan A. Holland, Kathy Holt, Daniel E. Holz, Paul Hopkins, Christian Horst, James Hough, Eric J. Howell, Charlie G. Hoy, Yiwen Huang, Moritz T. Hübner, Eliu A. Huerta, Dominique Huet, Brennan Hughey, Victor Hui, Sascha Husa, Sabina H. Huttner, Rachael Huxford, Tien Huynh-Dinh, Bartosz Idzkowski, Alberto Iess, Henri Inchauspe, Craig Ingram, Giuseppe Intini, Isac, Jean M., Max Isi, Bala R. Iyer, Thibaut Jacqmin, Sameer J. Jadhav, Shreejit P. Jadhav, Alasdair L. James, Karan Jani, Nagaraj N. Janthalur, Piotr Jaranowski, Deep Jariwala, Rafel Jaume, Alex C. Jenkins, Jun Jiang, Grace R. Johns, Aaron W. Jones, Ian I. Jones, Jeff D. Jones, Philip Jones, Russell Jones, Reinier J. G. Jonker, Ju Ju, Jonas Junker, Chinmay V. Kalaghatgi, Vassiliki Kalogera, Brittany Kamai, Shivaraj Kandhasamy, Gungwon Kang, Jonah B. Kanner, Shasvath J. Kapadia, Sudarshan Karki, Rahul Kashyap, Marie Kasprzack, Wolfgang Kastaun, Stavros Katsanevas, Erik Katsavounidis, William Katzman, Steffen Kaufer, Keita Kawabe, Fabien Kéfélian, David Keitel, Azadeh Keivani, Ross Kennedy, Joey S. Key, Sudiksha Khadka, Farit Y. Khalili, Imran Khan, Sebastian Khan, Zaki A. Khan, Efim A. Khazanov, Nandita Khetan, Mohammad Khursheed, Nutsinee Kijbunchoo, Chunglee Kim, Grace J. Kim, Jeongcho C. Kim, Kyungmin Kim, Won Kim, Whansun S. Kim, Young-min Kim, Charles Kimball, Peter J. King, Maya Kinley-Hanlon, Robin Kirchhoff, Jeffrey S. Kissel, Lisa Kleybolte, Sergei Klimenko, Tyler D. Knowles, Philip Koch, Sina M. Koehlenbeck, Gideon Koekoek, Soumen Koley, Veronica Kondrashov, Antonios Kontos, Nico Koper, Mikhail Korobko, William Z. Korth, Manoj Kovalam, Dan B. Kozak, Volker Kringel, Nv V. Krishnendu, Andrzej Królak, Natalie Krupinski, Gerrit Kuehn, Anil Kumar, Prayush Kumar, Rahul Kumar, Rakesh Kumar, Sumit Kumar, Ling-chi Kuo, Adam Kutynia, Benjamin D. Lackey, Danny Laghi, Emile Lalande, Lam L. Lam, Astrid Lamberts, Michael Landry, Benjamin B. Lane, Ryan N. Lang, Jacob Lange, Brian Lantz, Robert K. Lanza, Iuri La Rosa, Angelique Lartaux-Vollard, Paul D. Lasky, Michael Laxen, Albert Lazzarini, Claudia Lazzaro, Paola Leaci, Sean Leavey, Yannick K. Lecoeuche, Chang-hwan H. Lee, Hyung-mok M. Lee, Hyungwon W. Lee, Joongoo Lee, Kyung-ha Lee, Johannes Lehmann, Nicolas Leroy, Nicolas Letendre, Yuri Levin, Alvin K. Y. Li, Jin Li, Kaye li, Tjonnie G. F. Li, Xiang Li, Frank Linde, Seth D. Linker, Jethro N. Linley, Tyson B. Littenberg, Liu Liu, Xiaoshu Liu, Miquel Llorens-Monteagudo, Ka-lok Lo, Alexandra Lockwood, Lionel T. London, Alessandro Longo, Matteo Lorenzini, Vincent Loriette, Marc Lormand, Giovanni Losurdo, James D. Lough, Carlos O. Lousto, Geoffrey Lovelace, Harald Lück, Diana Lumaca, Andrew P. Lundgren, Ma Yiqiu, Ronaldas Macas, Sean Macfoy, Myron MacInnis, Duncan M. Macleod, Ian O. MacMillan, Adrian Macquet, Ignacio Magaña Hernandez, Fabian Magaña-Sandoval, Ryan M. Magee, Ettore Majorana, Ivan Maksimovic, Asmita Malik, Catherine Man, Vuk Mandic, Valentina Mangano, Georgia L. Mansell, Michael Manske, Maddalena Mantovani, Michela Mapelli, Fabio Marchesoni, Frederique Marion, Szabolcs Márka, Zsuzsanna Márka, Charalampos Markakis, Ashot S. Markosyan, Aaron Markowitz, Ed Maros, Antonio Marquina, Sylvain Marsat, Filippo Martelli, Ian W. Martin, Rodica M. Martin, Valerie Martinez, Denis V. Martynov, Hossein Masalehdan, Ken Mason, Elena Massera, Alain Masserot, Thomas J. Massinger, Mariela Masso-Reid, Simone Mastrogiovanni, Andrew Matas, Fabrice Matichard, Nergis Mavalvala, Emily Maynard, Joshua J. McCann, Richard McCarthy, David E. McClelland, Scott McCormick, Lee McCuller, Stephen C. McGuire, Connor McIsaac, Jessica McIver, David J. McManus, Terry McRae, Sean T. McWilliams, Duncan Meacher, Grant D. Meadors, Moritz Mehmet, Ajit K. Mehta, Elena Mejuto Villa, Andrew Melatos, Gregory Mendell, Adam A. Mercer, Lorenzo Mereni, Kara Merfeld, Edmond L. Merilh, Jonathan D. Merritt, Mourad Merzougui, Syd Meshkov, Chris Messenger, Cody Messick, Remi Metzdorff, Patrick M. Meyers, Fabian Meylahn, Ashish Mhaske, Andrea Miani, Haixing Miao, Ioannis Michaloliakos, Christophe Michel, Hannah Middleton, Leopoldo Milano, Andrewlawrence L. Miller, Meg Millhouse, Joseph C. Mills, Edoardo Milotti, Michael C. Milovich-Goff, Olivier Minazzoli, Yuri Minenkov, Alec Mishkin, Chandra Mishra, Timesh Mistry, Sanjit Mitra, Valery P. Mitrofanov, Guenakh Mitselmakher, Richard Mittleman, Geoffrey Mo, Kentaro Mogushi, Satyanarayan R. P. Mohapatra, Siddharth R. Mohite, Manel Molina-Ruiz, Marina Mondin, Matteo Montani, Christopher J. Moore, Dan Moraru, Filip Morawski, Gerardo Moreno, Soichiro Morisaki, Benoit Mours, Conor M. Mow-Lowry, Simone Mozzon, Federico Muciaccia, Arunava Mukherjee, Debnandini Mukherjee, Soma Mukherjee, Subroto Mukherjee, Nikhil Mukund, Adam Mullavey, Jesper Munch, Erik A. Muñiz, Peter G. Murray, Alessandro Nagar, Ilaria Nardecchia, Luca Naticchioni, Rajesh K. Nayak, Benjamin F. Neil, Joshua Neilson, Gijs Nelemans, Timothy J. N. Nelson, Marina Nery, Ansel Neunzert, Kwan-yeung Y. Ng, Sebastian Ng, Catherine Nguyen, Philippe Nguyen, David Nichols, Shania A. Nichols, Samaya Nissanke, Flavio Nocera, Minkyun Noh, Chris North, Devon Nothard, Laura K. Nuttall, Jason Oberling, Brendan D. O’Brien, Gor Oganesyan, Greg H. Ogin, John J. Oh, Sanghoon H. Oh, Frank Ohme, Hiroaki Ohta, Marcos A. Okada, Miquel Oliver, Christian Olivetto, Patrick Oppermann, Richard Oram, Brian O’Reilly, Rich G. Ormiston, Luis F. Ortega, Richard O’Shaughnessy, Serguei Ossokine, Charles Osthelder, David J. Ottaway, Harry Overmier, Ben J. Owen, Alexander E. Pace, Giulia Pagano, Michael A. Page, Giulia Pagliaroli, Archana Pai, Siddhesh A. Pai, Jordan R. Palamos, Oleg Palashov, Cristiano Palomba, Howard Pan, Pratap K. Panda, Tsun-ho Pang, Chris Pankow, Francesco Pannarale, Brijesh C. Pant, Federico Paoletti, Andrea Paoli, Abhishek Parida, William Parker, Daniela Pascucci, Antonio Pasqualetti, Roberto Passaquieti, Diego Passuello, Barbara Patricelli, Ethan Payne, Brynley L. Pearlstone, Thida C. Pechsiri, Ari J. Pedersen, Mike Pedraza, Arnaud Pele, Steven Penn, Albino Perego, Carlos J. Perez, Perigois Périgois, Antonio Perreca, Stephane Perriès, Jan Petermann, Harald P. Pfeiffer, Margot Phelps, Khun S. Phukon, Ornella J. Piccinni, Mikhael Pichot, Marco Piendibene, Francesco Piergiovanni, Vincenzo Pierro, Gabriel Pillant, Laurent Pinard, Innocenzo M. Pinto, Krzysztof Piotrzkowski, Marc Pirello, Matthew Pitkin, Wolfango Plastino, Rosa Poggiani, Yat-tung T. Pong, Sarah Ponrathnam, Pasquale Popolizio, Ed K. Porter, Jade Powell, Atul K. Prajapati, Kiran Prasai, Raghurama Prasanna, Geraint Pratten, Tanner Prestegard, Maria Principe, Giovanni A. Prodi, Leonid Prokhorov, Michele Punturo, Paola Puppo, Michael Pürrer, Hong Qi, Volker Quetschke, Pedro J. Quinonez, Fred J. Raab, Geert Raaijmakers, Hugh Radkins, Nicholas Radulesco, Peter Raffai, Hanna Rafferty, Sendhil Raja, Rajan Rajan, Binod Rajbhandari, Malik Rakhmanov, Karla E. Ramirez, Antoni Ramos-Buades, Javed Rana, Kaushik Rao, Piero Rapagnani, Vivien Raymond, Massimiliano Razzano, Jocelyn Read, Tania Regimbau, Luca Rei, Stuart Reid, David H. Reitze, Piero Rettegno, Fulvio Ricci, Colter J. Richardson, Jonathan W. Richardson, Paul M. Ricker, Gunnar Riemenschneider, Keith Riles, Monica Rizzo, Norna A. Robertson, Florent Robinet, Alessio Rocchi, Ramon D. Rodriguez-Soto, Loic Rolland, Jameson G. Rollins, Vincent J. Roma, M. Romanelli, Rocco Romano, Chandra L. Romel, Isobel M. Romero-Shaw, Janeen H. Romie, Caitlin A. Rose, Dakota Rose, Kyle Rose, Dorota Rosińska, Shawn G. Rosofsky, Michael P. Ross, Sheila Rowan, Samuel J. Rowlinson, Palash K. Roy, Santosh Roy, Soumen Roy, Paolo Ruggi, Guntis Rutins, Kyle Ryan, Surabhi Sachdev, Travis Sadecki, Mairi Sakellariadou, Om S. Salafia, Livio Salconi, Muhammed Saleem, Anuradha Samajdar, Eduardo J. Sanchez, Luis E. Sanchez, Nicolas Sanchis-Gual, Jaclyn R. Sanders, Kevin A. Santiago, Edison Santos, Nikhil Sarin, Benoit Sassolas, B S. Sathyaprakash, Orion Sauter, Richard L. Savage, Vaibhav Savant, Disha Sawant, Sihem Sayah, Dean Schaetzl, Paul Schale, Mark Scheel, Jacob Scheuer, Patricia Schmidt, Roman Schnabel, Robert M. S. Schofield, Axel Schönbeck, Emil Schreiber, Bernd W. Schulte, Bernard F. Schutz, Otto Schwarm, Eyal Schwartz, Jamie Scott, Susan M. Scott, Ed Seidel, Danny Sellers, Anand S. Sengupta, Noah Sennett, Daniel Sentenac, Valeria Sequino, Alexander Sergeev, Yoshinta Setyawati, Daniel A. Shaddock, Thomas Shaffer, Selim S. Shahriar, A. Sharma, Priyanka Sharma, Peter Shawhan, Hongyu Shen, Minori Shikauchi, Rosalie Shink, David H. Shoemaker, Deirdre M. Shoemaker, Keerti Shukla, Shyamsundar ShyamSundar, Karelle Siellez, Magdalena Sieniawska, Daniel Sigg, Leo P. Singer, Divya Singh, Neha Singh, Ayatri Singha, Akshat Singhal, Alicia M. Sintes, Valeria Sipala, Vasileios Skliris, Bram J. J. Slagmolen, Teresa J. Slaven-Blair, Jiri Smetana, Joshua R. Smith, Rory J. E. Smith, Surendranadh Somala, Edwin J. Son, Siddharth Soni, Borja Sorazu, Viola Sordini, Fiodor Sorrentino, Tarun Souradeep, Eric Sowell, Andrew P. Spencer, Mario Spera, Amit K. Srivastava, Varun Srivastava, Kai Staats, Cosmin Stachie, Mark Standke, Daniele A. Steer, Michael Steinke, Jessica Steinlechner, Sebastian Steinlechner, Daniel Steinmeyer, Dane Stocks, David J. Stops, Madeline Stover, Ken A. Strain, Giulia Stratta, Amber Strunk, Riccardo Sturani, Amber L. Stuver, Sudhagar Sudhagar, Vivishek Sudhir, Tiffany Z. Summerscales, Ling Sun, Sunil Sunil, Ankan Sur, Jishnu Suresh, Patrick J. Sutton, Bas L. Swinkels, Marek J. Szczepańczyk, Matteo Tacca, Simon C. Tait, Colm Talbot, Andres J. Tanasijczuk, David B. Tanner, Duo Tao, Marton Tápai, Amauri Tapia, Enzo N. Tapia San Martin, Jay D. Tasson, Robert Taylor, Rodrigo Tenorio, Lukas Terkowski, Manasadevi P. Thirugnanasambandam, Michael Thomas, Patrick Thomas, Jonathan E. Thompson, Sivananda R. Thondapu, Keith A. Thorne, Eric Thrane, Calley L. Tinsman, Saravanan R. Saravanan, Shubhanshu Tiwari, Srishti Tiwari, Vaibhav Tiwari, Karl Toland, Mauro Tonelli, Zeno Tornasi, Alejandro Torres-Forné, Calum I. Torrie, I. Tosta e Melo, Daniel Töyrä, Emily A. Trail, Flavio Travasso, Gary Traylor, Maria C. Tringali, Aashish Tripathee, Agata Trovato, Randy J. Trudeau, Ka-wa W. Tsang, Maggie Tse, Rhondale Tso, Leo Tsukada, Daichi Tsuna, Takuya Tsutsui, Margherita Turconi, Amit S. Ubhi, Koh Ueno, Dennis Ugolini, Cs S. Unnikrishnan, Alexander L. Urban, Samantha A. Usman, Andrei C. Utina, Henning Vahlbruch, Gabriele Vajente, Guillermo Valdes, Michele Valentini, M. Vallisneri, Niels van Bakel, Martin van Beuzekom, Jo F. J. van den Brand, Chris Van Den Broeck, Daniel C. Vander-Hyde, Laura van der Schaaf, Joris V. Van Heijningen, Marielle A. van Veggel, Marco Vardaro, Vijay Varma, Steve Vass, Matyas Vasúth, Alberto Vecchio, Gabriele Vedovato, John Veitch, Peter J. Veitch, Krishna Venkateswara, Gautam Venugopalan, Didier Verkindt, Doga Veske, Flavio Vetrano, Andrea Viceré, Aaron D. Viets, Serena Vinciguerra, David J. Vine, Jeanyves Vinet, Salvatore Vitale, Francisco Hernandez Vivanco, Thomas Vo, Helios Vocca, Cheryl Vorvick, Sergey P. Vyatchanin, Andrew R. Wade, Leslie E. Wade, Madeline Wade, Rob Walet, Marissa Walker, Gavin S. Wallace, Larry Wallace, Sinead Walsh, Jonathan Z. Wang, Sibo Wang, Wenhui H. Wang, Yifan F. Wang, Robert L. Ward, Zane A. Warden, Jim Warner, Michal Was, Jennifer Watchi, Betsy Weaver, Li-wei Wei, Michael Weinert, Alan J. Weinstein, Rainer Weiss, Felix Wellmann, Linqing Wen, Peter Weßels, Jonathan W. Westhouse, Karl Wette, John T. Whelan, Bernard F. Whiting, Chris Whittle, Dennis M. Wilken, Daniel Williams, Williams, Roy D., Andrew R. Williamson, Joshua L. Willis, Benno Willke, Walter Winkler, Christopher C. Wipf, Holger Wittel, Graham Woan, Janis Woehler, Jared K. Wofford, Chun-fung Wong, Jennifer L. Wright, David S. Wu, Daniel M. Wysocki, Liting Xiao, Hiro Yamamoto, Le Yang, Yang Yang, Ziyan Yang, Min-jet J. Yap, Maher Yazback, David W. Yeeles, Hang Yu, Haocun Yu, Shingheirobin Yuen, Adam K. Zadrożny, Adam Zadrożny, Michele Zanolin, Tatiana Zelenova, Jean-pierre Zendri, Michael Zevin, Jue Zhang, Liyuan Zhang, Teng Zhang, Chunnong Zhao, Guoying Zhao, Minchuan Zhou, Zifan Zhou, Xingjiang J. Zhu, Aaron B. Zimmerman, Michael E. Zucker, and John Zweizig

Abstract

Advanced LIGO and Advanced Virgo are monitoring the sky and collecting gravitational-wave strain data with sufficient sensitivity to detect signals routinely. In this paper we describe the data recorded by these instruments during their first and second observing runs. The main data products are gravitational-wave strain time series sampled at 16384 Hz. The datasets that include this strain measurement can be freely accessed through the Gravitational Wave Open Science Center at http://gw-openscience.org, together with data-quality information essential for the analysis of LIGO and Virgo data, documentation, tutorials, and supporting software.

Published
2021
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28. 4CPS-111 Efectiveness and cost of abiraterone and enzalutamide in prostate cancer

Author

Selvi, P, Pérez, O Montero, Madroéñal, I Carrion, Yaéññez, D, Gomez, E Sanchez, and Martin, CBocanegra

Abstract

BackgroundAbiraterone and enzalutamide are expensive drugs used in hospitals for metastatic prostate cancer and it is necessary to evaluate health outcomes from its use to establish whether it is cost effectivePurposeTo analyse the effectiveness and cost of abitarerone and enzalutamide in asymptomatic or mildly symptomatic metastatic castration-resistant prostate cancer patients (mCRPC) to whom chemotherapy is not clinically indicated and in those whose disease has progressed after docetaxel chemotherapy regimen-based.Material and methodsA retrospective descriptive study covering the period from January 2013 to June 2017 of mCRPC patients starting treatment with abiraterone or enzalutamide between January 2013 and June 2016 was performed. Parameters collected were: age, sex, drug, previous chemotherapy, progression-free survival (PFS) and economic spending. Data were collected from the Electronic Prescription Software Prisma®and the program of electronic patient records Diraya®and afterwards, organised in an Excel®base design for this study.ResultsA total of 74 patients with a median age of 76 years, 53 chemotherapy-naive and 21 chemotherapy-treated, were included. Fifty-nine patients were treated with abiraterone and 15 with enzalutamide. The mean PFS was 12.3 months with 49.2% of 1 year PFS. However, in the group of chemotherapy-naive patients it was 15 months, with 56% of 1 year PFS and 9.6 months (28% of 1 year PFS) in chemotherapy-treated patients. No difference was found between abiraterone group (12.4 PFS) and the enzalutamide group (12 PFS) nor in the age of the groups where PFS was 13 months in patients younger than 75 years and 12 months in those older than 75. The cost of treatment/patient was €35 559 and the total expenditure was €2,631,366 (2% of the total pharmacy service budget).ConclusionThe results of the effectiveness regarding PFS are lower than the ones obtained in the pivotal studies ‘301 and 302’ (abiraterone) and ‘PREVAIL and AFFIRM (enzalutamide). Chemoterapy-naive patients have better PFS than chemotherapy-treated and there is no difference between the abiraterone group and the enzalutamide group. The cost of abiraterone and enzalutamida per life-year gained were less than €30 000.References and/or AcknowledgementsPivotal study 301 & 302 Pivotal study PREVAIl & AFFIRMNo conflict of interest

Published
2018
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29. 5PSQ-042 Acute eosinophilic pneumonia secondary to daptomycin: a case report

Author

Feria, D Yááñez, Rey, MB Contreras, Gomez, E Sanchez, Saiz, S Grutzmancher, and Martin, C Bocanegra

Abstract

BackgroundA 81-years-old female was admitted due to a surgical cleaning of an infected knee prosthesis and the administration of targeted antibiotics. After starting with daptomycin, the patient developed an acute eosinophilic pneumonia.PurposeTo analyse whether the symptomathology was related to antibiotic treatment and to establish the cause.Material and methodsA descriptive observational study design was carried out. The medical history was obtained from the digital clinical history (DIRAYA) and the optimised computerised order entry software from the Pharmacy Department (APD-PRISMA). A bibliographic research was conducted to find similar cases or if it was an uncommon adverse effect. Modified Karch–Lasagna’s algorithm was applied to assess the relationship between the acute eosinophilic pneumonia and daptomycin.ResultsAfter the surgical cleaning, fever appeared and the patient started with ceftazidime and linezolid treatment. In the intraoperative culture it was detected as methicillin-resistant Staphylococcus epidermidis showed most sensitivity to daptomycin. After 4 weeks with daptomycin 6 mg/kg/day, fever and dyspnea appeared. The x-ray study showed bilateral pneumonia with eosinophylia and the patient needed admission to an intensive care unit. A new culture was obtained and the results were negative. With the suspicion of an eosinophilic pneumonia and after being the EPAR-Product Information was consulted, daptomycin was switched to vancomycin 30 mg/kg/day for the treatment of prosthesis infection, empiric antibiotic therapy was suspended and methylprednisolone was prescribed to treat the eosinophilic pneumonia. Five days’ later, the patient was discharged with positive synovial fluid cultures and a prescription of a once-weekly dalbavancin. After 4 weeks of treatment, cultures were negative. In contrast with notified case series, Staphylococcus aureuswas not the causative strain in our case.1Modified Karch–Lasagna’s algorithm established a ‘probable’ relationship between daptomycin and eosinophilic pneumonia. Adverse effect was reported to the local pharmacovigilance centre.ConclusionOur data suggest that daptomycin could provoke serious adverse effects and prolongation of hospitalisation time. Hospital pharmacists must perceive possible drug adverse effects and establish reporting systems to contribute to appropriate pharmacotherapy management.Reference and/or Acknowledgements1. Uppal P, LaPlante KL, Gaitanis MM, Jankowich MD, Ward KE. Daptomycin-induced eosinophilic pneumonia: A systematic review. Antimicrob Resist & Infect Control[Internet] 2016;5(1):55.No conflict of interest

Published
2018
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31. 4CPS-159 Quality of life assessment and efficacy of secukinumab in plaque psoriasis disease

Author

Ruiz, M Pedrosa, Carmona, I Moya, Yañez, E Sanchez, and Ovies, JM Fernandez

Abstract

BackgroundSecukinumab has demonstrated efficacy in moderate to severe plaque psoriasis (PP) by improving the Psoriasis Area and Severity Index (PASI), but patients’ quality of life is not always quantified in clinical trials.PurposeTo evaluate the efficacy of secukinumab in PP treatment and how it affects patients’ quality of life.Material and methodsAn observational and prospective study was conducted. Patients diagnosed with moderate to severe PP who began treatment with secukinumab in the period between January 2016 and June 2017 were included. Patients that did not complete at least 16 weeks with the treatment and those who did not sign the written informed consent form were excluded. To evaluate the response to secukinumab, PASI score was measured before and after 16 weeks of treatment: data obtained from the hospital database. The results on PASI were presented as a percentage response rate: PASI 75, PASI 90 and PASI 100. The participants filled out the Dermatology Quality of Life Index (DLQI) questionnaire: DLQI A (before secukinumab) and DLQI B (week 16) in our hospital Pharmacy Department.ResultsThe study was carried out in 36 patients. Average age was 48.8 years (34–67). Median time since diagnosis of PP was 17.6 years (6–32). All patients had been treated with metotrexate before starting biologic therapy. 86.1% of patients were previously exposed to biologics, 25 had been treated with anti-TNF agents (etanercept, infliximab and/or adalimumab), six had been treated with anti- IL12/IL13 (ustekinumab) and 5 were naive. Medium PASI score before and after 16 weeks of treatment was 21.5 (9–35) and 1.7 (0–10) respectively. Average score of DLQI A was 20.1 (6–28) and 1.3 (0–11) for DLQI B. PASI 100 was achieved in 58.3% of patients (21), PASI 75 responders were 22.2% and 19.4% did not reach PASI 75. Patients who reached the best DLQI variation were those who achieved PASI 100.ConclusionSecukinumab is a good alternative to naive patients and those who have not had a good response to other biologics. According to the correlation between PASI and DLQI scores, the more efficacy in treatment, the better improvement in quality of life.No conflict of interest

Published
2018
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37. Cardiovascular Health Research in the Workplace: A Workshop Report.

Author

Calitz C, Pratt C, Pronk NP, Fulton JE, Jinnett K, Thorndike AN, Addou E, Arena R, Brown AGM, Chang CC, Latts L, Lerner D, Majors M, Mancuso M, Mills D, Sanchez E, and Goff D

Subjects
American Heart Association, Heart Diseases epidemiology, Heart Diseases prevention & control, Humans, Stroke epidemiology, Stroke prevention & control, United States, Health Promotion, Occupational Health, Workplace
Abstract

Heart disease and stroke are the first and fifth leading causes of death in the United States, respectively. Employers have a unique opportunity to promote cardiovascular health, because >60% of US adults are employed, and most spend half of their waking hours at work. Despite the scope of the opportunity, <1 in 5 businesses implement evidence-based, comprehensive workplace health programs, policies, and practices. Integrated, systems-based workplace health approaches that harness data science and technology may have the potential to reach more employees and be cost-effective for employers. To evaluate the role of the workplace in promoting cardiovascular health across the lifespan, the National Heart, Lung, and Blood Institute, the National Institute for Occupational Safety and Health, and the American Heart Association convened a workshop on March 7, 2019, to share best practices, and to discuss current evidence and knowledge gaps, practical application, and dissemination of the evidence, and the need for innovation in workplace health research and practice. This report presents the broad themes discussed at the workshop and considerations for promoting worker cardiovascular health, including opportunities for future research.

Published
2021
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