29 results on '"Delpech, B."'
Search Results
2. The agonist SR 146131 and the antagonist SR 27897 occupy different sites on the human CCK1 receptor
- Author
-
Gouldson, P., Legoux, P., Carillon, C., Delpech, B., Fur, G. Le, Ferrara, P., and Shire, D.
- Published
- 2000
- Full Text
- View/download PDF
3. Measurement of Bone Mineral Density by Dual X-ray Absorptiometry in Paget's Disease Before and After Pamidronate Treatment
- Author
-
Laroche, M., Delpech, B., Bernard, J., Constantin, A., and Mazières, B.
- Abstract
Abstract.: Third-generation bisphosphonates are now currently used in the treatment of Paget's disease of bone. Dual X-ray absorptiometry may make it possible to quantify the action of these bisphosphonates on bone mineral density (BMD) in pagetic and nonpagetic bone. We used Lunar DPX, a total-body software program (automatic analysis and/or manual windows according to the site and bilateral or unilateral pagetic involvement) to study BMD in 28 patients (18 men, 10 women, mean age 69.8 years) with Paget's disease before and 6 months after infusions of 60 mg (alkaline phosphatase <350 IU) or 120 mg (ALP >350 IU) of pamidronate. Before treatment, in the 28 patients, the BMD of trabecular pagetic bone was 25% higher than that of nonpagetic bone; in cortical pagetic bone the BMD was 35% higher. After treatment, the BMD of trabecular pagetic bone increased by only 1.17%. the BMD of cortical pagetic bone increased by 1.37% whereas nonpagetic cortical bone lost 0.84%, independently of the levels of parathyroid hormone or the administration of calcium and vitamin D.
- Published
- 1999
- Full Text
- View/download PDF
4. Contrasting roles of Leu^3^5^6 in the human CCK1 receptor for antagonist SR 27897 and agonist SR 146131 binding
- Author
-
Gouldson, P., Legoux, P., Carillon, C., Delpech, B., Fur, G. Le, Ferrara, P., and Shire, D.
- Published
- 1999
- Full Text
- View/download PDF
5. Inhibition of in vitro lymphocyte proliferation by brain glycoprotein (NSA3) and mesenchyme-associated antigen (MAA)
- Author
-
Gilbert, D., Delpech, B., Chevrier, A., and Halavent, C.
- Abstract
Two cross-reacting antigens, one (NSA
3 ) associated with nervous system and the other (MAA) present in mesenchyme and different types of tumors, were shown to inhibit the mitogenic effect of PHA, Con-A, and PPD on normal peripheral human lymphocytes. They do not affect the response to allogeneic cells in the one-way mixed lymphocyte reaction. The two antigens also suppress in vitro response to PPD obtained with lymphocytes isolated from BCG-treated patients. The lack of effect on unstimulated lymphocytes and on MLR allows the exclusion of cytotoxic action by our antigen preparations. These data, taken in conjunction with previously obtained results concerning inhibition of E active rosette formation, give rise to the hypothesis of an antigen action directed against a T cell subpopulation. These results also suggest that MAA, in association with other tissue and tumor factors, could play a role in tumor-induced immunosuppression.- Published
- 1981
- Full Text
- View/download PDF
6. Etude en résonance magnétique nucléaire du 13C des paramètres de substitution de la fonction azide
- Author
-
Pancrazi, A., Kaboré, I., Delpech, B., Astier, A., Khuong-Huu, Q., and Lukacs, G.
- Abstract
The various effects (α, β, γ and δ) on the 13C nmr of azido steroids have been measured. For cyclohexane azides constrained to equatorial and axial configurations, the α-effects were determined to be 33.6 and 31.2 ppm. Both γ- and δ-effects have magnitudes near those for OH and NH2groups. On the other hand, the β-effect of the azides is slightly smaller than those of hydroxyls or amines as its magnitude is reduced by a γ-effect of the second nitrogen atom of the azide group. This additional γ-effect is a function of the spatial arrangement of the Cβ—H bond with respect to the azide group. [Journal translation]
- Published
- 1977
- Full Text
- View/download PDF
7. The extracellular matrix during neural crest formation and migration in rat embryos
- Author
-
Poelmann, R. E., Gittenberger-de Groot, A. C., Mentink, M. M. T., Delpech, B., Girard, N., and Christ, B.
- Abstract
Changes in the distribution of extracellular matrix components have been investigated immunohistochemically during neural crest development in the rat. Inside the ectodermal epithelium basal lamina components are formed resulting in a separation of neurectoderm and epidermal ectoderm. Within the presumptive neural crest area fibronectin, hyaluronan and chondroitin sulphate become apparent. Upon subsequent neural crest migration the basal lamina becomes disrupted. As the neural crest cells take part in mesectoderm formation, fragments of the basal lamina remain attached to their surface, as is demonstrated with antibodies against laminin and collagen type IV. The extracellular matrix is therefore active both in the separation of neuroectoderm from epidermal ectoderm and in mesectoderm formation.
- Published
- 1990
- Full Text
- View/download PDF
8. Maternal protein restriction early in rat pregnancy alters brain development in the progeny
- Author
-
Gressens, P., Muaku, S. M., Besse, L., Nsegbe, E., Gallego, J., Delpech, B., Gaultier, C., Evrard, P., Ketelslegers, J.-M., and Maiter, D.
- Published
- 1997
- Full Text
- View/download PDF
9. Effect of aging on neointima formation and hyaluronan, hyaluronidase and hyaluronectin production in injured rat aorta
- Author
-
Chajara, A., Delpech, B., Courel, M.-N., Leroy, Marcelle, Basuyau, J.-P., and Levesque, H.
- Published
- 1998
- Full Text
- View/download PDF
10. Standardization of mRNA titration using a polymerase chain reaction method involving co-amplification with a multispecific internal control.
- Author
-
Bouaboula, M, Legoux, P, Pességué, B, Delpech, B, Dumont, X, Piechaczyk, M, Casellas, P, and Shire, D
- Abstract
We describe a simplified and reliable polymerase chain reaction-based method for assaying RNAs of low abundancy. The technique involves the co-amplification of cellular RNA-derived cDNA with a multispecific cDNA of synthetic origin added as an internal standard, using primer pairs common to both templates. We show that the co-amplified templates accumulate in a parallel manner throughout both the exponential and nonexponential phases of amplification, even when the starting amounts of the templates differ by up to 2 orders of magnitude. This finding means that preliminary experiments designed to determine either the late exponential region or the amplification efficiency for each pair of primers are unnecessary. This has enabled us to develop a greatly simplified quantitation protocol. We illustrate our approach by quantifying the effect of the immunosuppressor cyclosporin A on the accumulation of interleukin-4, interferon-gamma, and interleukin-2 receptor mRNAs in phytohemagglutinin-stimulated human peripheral blood mononuclear cells.
- Published
- 1992
- Full Text
- View/download PDF
11. Abstracts
- Author
-
Derlon, J. M., Petit-taboué, M. C., Dauphin, F., Courtheoux, P., Chapon, F., Creissard, P., Darcel, F., Houtteville, J. P., Kaschten, B., Sadzot, B., Stevenaert, A., Tjuvajev, Juri G., Macapinlac, Homer A., Daghighian, Farhad, Ginos, James Z., Finn, Ronald D., Jiaju Zhang, M. S., Beattie, Bradley, Graham, Martin, Larson, Steven M., Blasberg, Ronald G., Levivier, M., Goldman, S., Pirotte, B., Brucher, J. M., Balériaux, D., Luxen, A., Hildebrand, J., Brotchi, J., Go, K. G., Kamman, R. L., Mooyaart, E. L., Heesters, M. A. A. M., Sijens, P. E., Oudksrk, M., van Dijk, P., Levendag, P. C., Vecht, Ch. J., Metz, R. J., Kennedy, D. N., Rosen, B. R., Hochberg, F. H., Fishman, A. J., Filipek, P. A., Caviness, V. S., Gross, M. W., Weinzierl, F. X., Trappe, A. E., Goebel, W. E., Frank, A. M., Becker, Georg, Krone, Andreas, Schmidt, Karsten, Hofmann, Erich, Bogdahn, Ulrich, Bencsch, H., Fclber, S., Finkenstedt, G., Kremser, C., Sfockhammer, G., Aichner, F., Bogdahn, U., Fröhlich, T., Becker, G., Krone, A., Schlief, R., Schürmann, J., Jachimczak, P., Hofmann, E., Roggendorf, W., Roosen, K., Carapella, C. M., Carpinelli, G., Passalacqua, R., Raus, L., Giannini, M., Mastrostefano, R., Podo, F., Tofani, A., Maslrostefano, R., Mottoles, M., Ferraironi, A., Scelsa, M. G., Oppido, P., Riccio, A., Maini, C. L., Collombier, L., Taillandier, L., Dcbouverie, M., Laurens, M. H., Thouvenot, P., Weber, M., Bertrand, A., Cruickshank, G. S., Patterson, J., Hadley, D., De Witte, Olivier, Hildebrand, Jerzy, Luxen, André, Goldman, Serge, Ernestus, R. -I., Bockhorst, K., Eis, M., Els, T., Hoehn-Berlage, M., Gliese, M., Fründ, R., Geissler, A., Woertgen, C., Holzschuh, M., Goldman, Serge, Levivier, M., Pirotte, B., Brucher, J. M., Luxen, A., Brotchi, J., Hildebrand, J., Hausmann, O., Merlo, A., Jerrnann, E., Uirich, J., Chiquet-Ehrismann, R., Müller, J., Mäcke, H., Gratzl, O., Herholz, K., Ghaemi, M., Würker, M., Pietrzyk, U., Heiss, W. -D., Kotitschke, K., Brandl, M., Tonn, J. C., Haase, A., Bogdahn, U., Kotitschke, K., Muigg, S., Felber, S., Aichner, F., Haase, A., Bogdahn, U., Krone, A., Becker, G., Woydt, M., Roggendorf, W., Hofmann, E., Bogdahn, U., Roosen, K., Lanfermann, Heinrich, Heindel, Walter, Kugel, Harald, Erneslus, Ralf -Ingo, Röhn, Gabricle, Lackner, Klaus, Metz, R. J., Kennedy, D. N., Pardo, F. S., Kutke, S., Sorensen, A. G., Hochberg, F. H., Fishman, A. J., Filipek, P. A., Rosen, B. R., Caviness, V. S., Mechtler, L. L., Withiam-Lench, S., Shin, K., Klnkel, W. R., Patel, M., Truax, B., Kinkel, P., Shin, K., Mechtler, L., Ricci, M., Pantano, P., Maleci, A., Pierallini, S., Di Stefano, D., Bozzao, L., Cantore, G. P., Röhn, Gabriele, Els, T., Schröder, R., Hoehn-Berlage, M., Ernestus, R. -I., Ruda, R., Mocellini, C., Soffietti, R., Campana, M., Ropolo, R., Riva, A., de Filippi, P. G., Schiffer, D., Salgado, D., Rodrigues, M., Salgado, L., Fonseca, A. T., Vieira, M. R., Bravo Marques, J. M., Satoh, H., Uozumi, T., Kiya, K., Kurisu, K., Arita, K., Sumida, M., Ikawa, F., Tzuk-Shina, Tz., Gomori, J. M., Rubinstein, R., Lossos, A., Siegal, T., Vaalburg, W., Paans, A. M. J., Willemsen, A. T. M., van Waarde, A., Pruim, J., Visser, G. M., Go, K. G., Valentini, S., Ting, Y. L. T., De Rose, R., Chidichimo, G., Corricro, G., van Lcycn-Pilgram, Karin, Erncslus, Ralf -Ingo, Klug, Norfried, van Leyen-Pilgram, K., Ernestus, R. -I., Schröder, R., Klug, N., Woydt, M., Krone, A., Tonn, J. C., Becker, G., Neumann, U., Roggendorf, W., Roosen, K., Plate, Karl H., Breier, Georg, Millaucr, Birgit, Weich, Herbert A., Ullrich, Axel, Risau, Werner, Roosen, N., Chopra, R. K., Mikkelsen, T., Rosenblum, S. D., Yan, P. S., Knight, R., Windham, J., Rosenblum, M. L., Schiffer, D., Attanasio, A., Cavalla, P., Chio, A., Giordana, M. T., Migheli, A., Amberger, V., Hensel, T., Schwab, M. E., Cervoni, Luigi, Celli, Paolo, Tarantino, Roberto, Huettner, C., Tonn, J. C., Berweiler, U., Roggendorf, W., Salmon, I., Rorive, S., Rombaut, K., Pirotte, B., Haot, J., Brotchi, J., Kiss, R., Maugard-Louboutin, C., Charrier, J., Fayet, G., Sagan, C., Cuillioere, P., Ricolleau, G., Martin, S., Menegalli-Bogeelli, D., Lajat, Y., Resche, F., Molnàr, Péter, Bárdos, Helga, Ádány, Róza, Rogers, J. P., Pilkington, G. J., Pollo, B., Giaccone, G., Allegranza, A., Bugiani, O., Prim, J., Badia, J., Ribas, E., Coello, F., Shezen, E., Lossos, A., Abramsky, O., Siegal, T., Scerrati, M., Roselli, R., Iacoangeli, M., Pompucci, A., Rossi, G. F., Deeb, Saleh M. Al., Koreich, Osama, Yaqub, Basim, Moutaery, Khalaf R. Al., Giordana, M. T., Cavalla, P., Chio, A., Marino, S., Vigliani, M. C., Schiffer, D., Deburghgraeve, V., Darcel, F., Gedouin, D., Hassel, M. Ben, Guegan, Y., Jeremic, B., Grujicic, D., Antunovic, V., Matovic, M., Shibamoto, Y., Kallio, Merja, Huhmar, Helena, Kudoh, Ch., Detta, A., Sugiura, K., Hitchcock, E. R., Mastrostefano, R., Di Russo, R., Cipriani§, M., Occhipinti, E. M., Conti, E. M. S., Clowegeser, A., Ortler, M., Seiwald, M., Kostron, H., Rajan, B., Ross, G., Lim, C., Ashlcy, S., Goode, D., Traish, D., Brada, M., Sanden, G. A. C. vd, Schouten, L. J., Coebergh, J. W. W., Razenberg, P. P. A., Twijnstra, A., Snilders-Keilholz, A., Voormolen, J. H. C., Hermans, J., Leer, J. W. H., Taillandier, L., Baylac, F., Dcbouvcrie, M., Anxionnal, R., Bracard, S., Vignand, J. M., Duprcz, A., Weber, M., Winking, M., Böker, D. K., Simmet, T., Rothbart, David, Strugar, John, Balledux, Jeroen, Criscuolo, Gregory R., Jachimczak, Piotr, Blesch, Armin, Heβdörfer, Birgit, Bogdahn, Ulrich, Ernestus, Ralf -Ingo, Schröder, Roland, Klug, Norfrid, Krouwer, H. G. J., Duinen, S. G. v., Algra, A., Zentner, J., Wolf, H. K., Ostertun, B., Hufnagel, A., Campos, M. G., Solymosi, L., Schramm, J., Newlands, E. S., O'Reilly, S. M., Brampton, M., Soffietti, R., Chio, A., Mocellini, C., Ruda, R., Vigliani, M. C., Schiffer, D., Sciolla, R., Seliak, D., Henriksson, R., Bergenheim, A. T., Björk, P., Gunnarsson, P. -O., Hariz, Ml., Grant, R., Collie, D., Gregor, A., Ebmeier, K. P., Jarvis, G., Lander, F., Cull, A., Sellar, R., Brada, M., Thomas, C., Elyan, S., Hines, F., Ashley, S., Stenning, S., Bernstein, J. J., Goldberg, W. J., Roelcke, U., Von Ammon, K., Hausmann, O., Radu, E. W., Kaech, D., Leenders, K. L., Fitzek, M. M., Aronen, J. Efird, Hochberg, F., Gruber, M., Schmidt, E., Rosen, B., Flschman, A., Pardo, P., Afra, U. M. U., Sipos, L., Slouik, F., Boiardi, A., Salmaggi, A., Pozzi, A., Farinotti, L., Fariselli, L., Silvani, A., Brandes, A., Scelzi, E., Rigon, A., Zampieri, P., Pignataro, M., Amanzo, P. D'., Amista, P., Rotilio, A., Fiorentino, M. V., Thomas, R., Brazil, L., O'Connor, A. M., Ashley, S., Brada, M., Salvati, Maurizio, Cervoni, Luigi, Puzzilli, Fabrizio, Cervoni, Luigi, Salvati, Maurizio, Raguso, Michele, Cruickshank, G. S., Duckworth, R., Rumpling, R., Rottuci, M., Fariselli, L., Boiardi, A., Broggi, G., Plrint, N. G., Sabattini, E., Manetto, V., Gambacorta, H., Poggi, S., Pileri, S., Ferracini, R., Grant, R., Plev, D. V., Hopf, N. J., Knosp, E., Bohl, J., Perncczky, A., Kiss, R., Salmon, I., Catnby, I., Dewitte, O., Brotchi, J., Pasteels, J. L., Camby, I., Salmon, I., Darro, F., Danguy, A., Brotchi, J., Pasteels, J. L., Kiss, R., Kiu, M. C., Lai, G. M., Yang, T. S., Ng, K. T., Chen, J. S., Chang, C. N., Leung, W. M., Ho, Y. S., Rychter, M. Deblec, Klimek, A., Liberski, P. P., Karpinaka, A., Krauseneck, P., Schöffel, V., Müller, B., Kreth, F. W., Faist, M., Warnke, P. C., Ostertag, C. B., Nielen, K. M. B. v., Visscr, M. C., Lebrun, C., Lonjon, M., Desjardin, T., Michiels, J. F., Chanalet, Sa. Lagrange J. L., Roche, J. L., Chatel, M., Mastronardi, L., Puzzilli, F., Osman, Farah J., Lunardi, P., Matsutani, M., Ushio, Y., Takakura, K., Menten, Johan, Hamers, Han, Ribot, Jacques, Dom, René, Tcepen, Hans, Müller, B., Weidner, N., Krauseneck, P., Naujocks, G., van Roost, D., Wiestler, O. D., Kuncz, A., Nieder, C., Setzel-Sesterhein, M., Niewald, M., Schnabel, I., O'Neill, K. S., Kitchen, N. D., Wilkins, P. R., Marsh, H. T., Pierce, E., Doshi, R., Deane, R., Previtali, S., Quattrini, A., Nemni, R., Ducati, A., Wrabetz, L., Canal, N., Punt, C. J. A., Stamatakis, L., Giroux, B., Rutten, E., Quigley, Matthew R., Beth Sargent, P. A. -C., Flores, Nicholas, Simon, Sheryl, Maroon, Joseph C., Quigley, Matthew R., Beth Sargent, P. A. -C., Flores, Nicholas, Maroon, Joseph C., Rocca, A. A., Gervasoni, C., Castagna, A., Picozzi, P., Giugni, E., Rocca, A. A., Tonnarelli, G. P., Ducati, A., Mangili, F., Truci, G., Canal, N., Giovanelli, M., Roelcke, U., Von Ammon, K., Radu, E. W., Leenders, K. L., Sachsenheimer, W., Bimmler, T., Seiwald, M., Eiter, H. Rhomberg W., Ortler, M., Obwegesser, A., Kostron, H., Steilen, H., Henn, W., Moringlane, J. R., Kolles, H., Feiden, W., Zang, K. D., Sleudel, W. I., Steinbrecher, Andreas, Schabet, Martin, Heb, Clemens, Bamberg, Michael, Dichgans, Johannes, Stragliotto, G., Delattre, J. Y., Poisson, M., Zampieri, P., Brandes, A., Rigon, A., Tosatto, L., D'Amanzo, P., Menicucci, N., Rotilio, A., Mingrino, S., Steudel, W. I., Feld, R., Henn, W., Zang, K. D., Maire, J. Ph., Caudry, M., Guerin, J., Celerier, D., Salem, N., Demeaux, H., Fahregat, J. F., Kusak, M. E., Bucno, A., Albisua, J., Jerez, P., Sarasa, J. L., Garefa, R., de Campos, J. M., Kusak, M. E., de Campos, J. M., Bueno, A., García-Delgado, R., Sarasa, J. L., García-Sola, R., Lantsov, A. A., Shustova, T. I., Lcnartz, D., Wellenreuther, R., von Deirnling, A., Köning, W., Menzel, J., Scarpa, S., Manna, A., Reale, M. G., Oppido, P. A., Carapella, C. M., Frati, L., Valery, C. A., Ichen, M., Foncin, J. P., Soubrane, C., Khayat, D., Philippon, J., Vaz, R., Cruz, C., Weis, S., Protopapa, D., März, R., Winkler, P. A., Reulen, H. J., Bise, K., Beuls, E., Berg, J., Deinsberger, W., Böker, D. K., Samii, M., Caudry, M., Darrouzet, V., Guérin, J., Trouette, R., Causse, N., Bébéar, J. P., Parker, F., Vallee, J. N., Carlier, R., Zerah, M., Lacroix-Jousselin, C., Piepmeier, Joseph M., Kveton, John, Czibulka, Agnes, Tigliev, G. S., Chernov, M. P., Maslova, L. N., Valdueza, José M., Jänisch, Werner, Bock, Alexander, Harms, Lutz, Bessell, E. M., Graus, F., Punt, J., Firth, J., Hope, T., Koriech, Osama, Al Deeb, Saleh, Al Moutaery, Khalaf, Yaqub, B., Silvani, A., Salmaggi, A., Pozzi, A., Franzini, A., Boiardi, A., Goldbrunner, R., Warmuth-Metz, M., Paulus, W., Tonn, J. -Ch., Roosen, K., Strik, I. I., Müller, B., Markert, C., Pflughaupt, K. -W., Krauseneck, P., O'Neill, B. P., Dinapoli, R. P., Voges, J., Sturm, V., Deuß, U., Traud, C., Treuer, H., Lehrke, R., Kim, D. G., Müller, R. P., Alexandrov, Yu. S., Moutaery, K., Aabed, M., Koreich, O., Ross, G. M., Rajan, B., Traish, D., Ashley, S., Ford, D., Brada, M., Schmeets, I. L. O., Jager, J. J., Pannebakker, M. A. G., de Jong, J. M. A., van Lindert, E., Knosp, E., Kitz, K., Blond, S., Dubois, F., Assaker, R., Baranzelli, M. C., Sleiman, M., Pruvo, J. P., Coche-Dequeant, B., Matsutani, M., Takakura, K., Sano, K., PetriČ-Grabnar, G., Jereb, B., Župančič, N., Koršič, M., Rainov, N. G., Burkert, W., Ushio, Yukitaka, Kochi, Masato, Itoyama, Youichi, de Campos, J. M., Kusak, M. E., Sarasa, J. L., García, R., Bueno, A., Ferrando, L., Hoang-Xuan, K., Sanson, M., Merel, P., Delattre, J. Y., Poisson, M., Delattre, O., Thomas, G., Hoang-Xuan, K., Delattre, J. Y., Poisson, M., Thomas, G., Haritz, D., Obersen, B., Grochulla, F., Gabel, D., Haselsberger, K., Radner, H., Pendl, G., Brada, M., Laing, R. W., Warrington, A. P., Nowak, P. J. C. M., Kolkman-Deurloo, I. K. K., Visser, A. G., Berge, Hv. d., Niël, C. G. J. H., Levendag, P. C., Bergström, P., Hariz, M., Löfroth, P. -O., Bergenheim, T., Henriksson, R., Blond, S., Assaker, R., Cortet-rudelli, C., Dewailly, D., Coche-dequeant, B., Castelain, B., Dinapoli, R., Shaw, E., Coffey, R., Earle, J., Foote, R., Schomberg, P., Gorman, D., Girard, N., Courel, M. N., Delpech, B., Haselsberger, K., Friehs, G. M., Schröttner, O., Pendl, G., Pötter, R., hawliczek, R., Sperveslage, P., Prott, F. J., Wachter, S., Dieckmann, K., Würker, M., Herholz, K., Pietrzyk, U., Voges, J., Treuer, H., Sturm, V., Bauer, B., Heiss, W. -D., Jund, R., Zimmermann, F., Feldmann, H. J., Gross, M. W., Kneschaurek, P., Molls, M., Lederman, G., Lowry, J., Wertheim, S., Voulsinas, L., Fine, M., Lederman, G., Lowry, J., Wertheim, S., Fine, M., Voutsinas, I., Qian, G., Rashid, H., Lederman, G., Lowry, J., Wertheim, S., Fine, M., Voulsinas, L., Qian, G., Rashid, H., Moutaery, K., Aabed, M., Koreich, O., Scerrati, M., Montemaggi, P., Iacoangeli, M., Pompucci, A., Roselli, R., Trignani, R., Rossi, G. F., Shin, K., Mechtler, L., West, C., Grand, W., Shin, K., Sibata, C., West, C., Mechtler, L., Grand, W., Thomas, R., Guerrero, D., James, N., Ashley, S., Gregor, A., Brada, M., Voges, J., Sturm, V., Bramer, R., Pahlke, H., Lehrke, R., Treuer, H., Banik, N., Kim, D. G., Hövels, M., Bernsen, H. J. J. A., Rijken, P. F. J. W., Van der Sanden, B. P. J., Hagemeier, N. E. M., Van der Kogel, A. J., Koehler, P. J., Verbiest, H., Jager, J., Vecht, Ch. J., Ross, G. M., McIlwrath, A., Brown, R., Mottolesb, C., Pierre'Kahn, A., Croux, M., Roche, J. L., Marchai, J., Delhemes, P., Tremoulet, M., Stilhart, B., Chazai, J., Caillaud, P., Ravon, R., Passacha, J., Bouffet, E., Dirven, C. M. F., Mooy, J. J. A., Molenaar, W. M., Lewandowicz, G. M., Grant, N., Harkness, W., Hayward, R., Thomas, D. G. T., Darling, J. L., Delepine, N., Subovici, I. I., Cornille, B., Markowska, S., Alkallaf, JC. Desbois, KühI, J., Niethammer, D., Spaar, H. J., Gnekow, A., Havers, W., Berthold, F., Graf, N., Lampert, F., Maass, E., Mertens, R., Schöck, V., Aguzzi, A., Boukhny, A., Smirtukov, S., Prityko, A., Hoiodov, B., Geludkova, O., Nikanorov, A., Levin, P., Rothbart, David, Balledux, Jeroen, Criscuolo, Gregory R., D'haen, B., Van Calenbergh, F., Casaer, P., Dom, R., Menten, J., Goffin, J., Plets, C., Hertel, A., Hernaiz, P., Seipp, C., Siegler, K., Baum, R. P., Maul, F. D., Schwabe, D., Jacobi, G., Kornhuber, B., Hör, G., Menten, J., Casaer, P., Pilkington, G. J., Merzak, A., Rooprai, H. K., Bullock, P., van Domburg, P. H. M. F., Wesseling, P., Thijssen, H. O. M., Wolff, J. E. A., Boos, J., Krähling, K. H., Gressner-Brocks, V., Jürgens, H., Schlegel, J., Scherthan, H., Arens, N., Stumm, Gabi, Kiessling, Marika, Merzak, A., Koochekpour, S., Pilkington, G. J., Reifenberger, G., Reifenberger, J., Liu, L., James, C. D., Wechsler, W., Collins, V. P., Fabel-Schulte, Klaus, Jachimczak, Plotr, Heßdörfer, Birgitt, Baur, Inge, Schlingensiepen, Karl -Hermann, Brysch, Wolgang, Bogdahn, Ulrich, Blesch, A., Bosserhoff, A. K., Apfel, R., Lottspeich, F., Jachimczak, P., Büttner, R., Bogdahn, U., Cece, R., Barajon, I., Tazzari, S., Cavaletti, G., Torri-Tarelli, L., Tredici, G., Hecht, B., Turc-Carel, C., Atllas, R., Chatel, M., Gaudray, P., Gioanni, J., Hecht, F., Balledux, Jeroen, Rothbart, David, Criscuolo, Gregory R., de Campos, J. M., Kusak, M. E., Rey, J. A., Bello, M. J., Sarasa, J. L., Dubois, F., Blond, S., Parent, M., Assaker, R., Gosselin, P., Christiaens, J. L., Feld, R., Moringlane, J. R., Steudel, W. I., Schaudies, J. R., Janka, M., Tonn, J. C., Fischer, U., Meese, E., Roosen, K., Remmelink, M., Salmon, I., Cras, P., Pasteels, J. L., Brotchi, J., Kiss, R., Bensadoun, R. J., Frenay, M., Formento, J. L., Milano, G., Lagrange, J. L., Grellier, P., Lee, J. -Y., Ernestus, R. -I., Riese, H. -H., Cervós-Navarro, J., Reutter, W., Lippitz, B., Scheitinger, C., Scholz, M., Weis, J., Gilsbach, J. M., Füzesi, L., Koochekpour, S., Merzak, A., Pilkington, G. J., Sanson, M., Li, Y. J., Hoang-Xuan, K., Delattre, J. Y., Poisson, M., Hamelin, R., Van de Kelft, Erik, Dams, Erna, Martin, Jean -Jacques, Willems, Patrick, Lehrke, R., Voges, J., Treuer, H., Erdmann, J., Müller, R. P., Sturm, V., Wurm, R. E., Warrington, A. P., Laing, R. W., Sardell, S., Hines, F., Graham, J. D., Brada, M., Ushio, Yukitaka, Kuratsu, Jun -ichi, Kochi, Masato, Kitz, K., Aichholzer, M., Rössler, K., Alesch, F., Ertl, A., Sorensen, P. S., Helweg-Larsen, S., Mourldsen, H., Hansen, H. H., El Sharoum, S. Y., Berfelo, M. W., Theunissen, P. H. M. H., Jager, J. J., de Jong, J. M. A., Fedorcsák, I., Nyáry, I., Osztie, É., Horvath, Á., Kontra, G., Frenay, M., Burgoni-chuzel, J., Paquis, P., Lagrange, J. L., Helweg-Larsen, S., Hansen, SW., Sørensen, PS., Salmon, I., Kiss, R., Krauseneck, P., Müller, B., Morche, M., Tonn, J. C., Lagerwaard, F. J., Levendag, P. C., Eijkenboom, W. M. H., Schmilz, P. I. M., Lentzsch, S., Weber, F., Franke, J., Dörken, B., Lunardi, P., Schettini, G., Osman, Farah J., Qasho, R., Mocellini, C., Ruda, R., Soffietti, R., Garabello, D., Sales, S., De Lucchi, R., Vasario, E., Schiffer, D., Muracciole, X., Régis, J., Manera, L., Peragut, J. C., Juin, P., Sedan, R., Nieder, C., Niewald, M., Walter, K., Schnabel, K., Nieder, C., Niewald, N., Nestle, U., Schnabel, K., Berberich, W., Oschmann, P., Theißen, R. D., Reuner, K. H., Kaps, M., Dorndorf, W., Martin, K. K., Akinwunmi, J., Rooprai, H. K., Kennedy, A., Linke, A., Ognjenovic, N., Pilkington, G. J., Svadovsky, A. I., Peresedov, V. V., Bulakov, A. A., Butyalko, M. Y., Zhirnova, I. G., Labunsky, D. A., Gnazdizky, V. V., Gannushkina, I. V., Taphoorn, M. J. B., Potman, R., Barkhof, F., Weerts, J. G., Karim, A. B. M. F., Heimans, J. J., van de Pol, M., van Aalst, V. C., Wilmink, J. T., Twijnstra, A., van der Sande, J. J., Boogerd, W., Kröger, R., Jäger, A., Wismeth, C., Dekant, A., Brysch, W., Schlingensiepen, K. H., Jachimczak, P., Bogdahn, U., Pirolte, B., Cool, V., Gérard, C., Levivier, M., Dargent, J. L., Goldman, S., Brotchi, J., Hildebrand, J., Velu, T., Herrlinger, U., Schabet, M., Ohneseit, P., Buchholz, R., Zhu, Jianhong, Reszka, Regina, Weber, Friedrich, Walther, Wolfgang, Zhang, L. I., Brock, Mario, Roosen, N., Rock, J. P., Zeng, H., Feng, J., Fenstermacher, J. D., Rosenblum, M. L., Siegal, T., Gabizon, A., Beljanski, M., Crochet, S., Bergenheim, A. T., Zackrisson, B., Elfverson, J., Bergström, P., Henriksson, R., Butti, G., Baetta, R., Magrassi, L., De Renzis, M. R., Soma, M. R., Davegna, C., Pezzotta, S., Paoletti, R., Fumagalli, R., Infuso, L., Sankar, A. A., Darling, J. L., Thomas, D. G. T., Defer, G. -L., Brugières, P., Gray, F., Chomienne, C., Poirier, J., Degos, L., Degos, J. D., Colombo, Bruno M., DiDonato, Stefano, Finocchiaro, Gaetano, Hebeda, K. M., Sterenborg, H. J. C. M., Saarnak, A. E., Wolbers, J. G., van Gemert, M. J. C., Kaaijk, P., Troost, D., Leenstra, S., Das, P. K., Bosch, D. A., Kostron, H., Hochleitner, B. W., Obwegeser, A., Ortler, M., Seiwald, M., Vooys, W., Krouwer, H. G. J., de Gast, G. C., Marx, J. J. M., Osman, Farah J., Lunardi, P., Puzzilli, F., Menovsky, T., Beek, J. F., Wolbers, J. G., van Gemert, M. J. C., Naujocks, G., Wiestler, O. D., Schirrmacher, V., Schramm, J., Schmitz, A., Eis-Hübinger, A. M., Piepmeier, p. h., Pedersen, Patricia, Greer, Charles, Quigley, Matthew R., Shih, Tommy, Elrifal, Amr, Rothfus, William, Maroon, Joseph C., Rohertson, L., Rampling, R., Whoteley, T. L., Piumb, J. A., Kerr, D. J., Falina, P. A., Crossan, I. M., Roosen, N., Rock, J. P., Feng, J., Zeng, H., Ho, K. L., Fenstermacher, J. D., Rosenblum, M. L., Ruchoux, M. M., Vincent, S., Jonca, F., Plouet, J., Lecomte, M., Samid, D., Thibault, A., Ram, Z., Oldfield, E. H., Myers, C. E., Reed, E., Schabet, M., Herrlinger, U., Buchholz, R., Shoshan, Y., Siegal, T., Siegal, T., Shezen, E., Siegal, Tz., Stockhammer, G., Rosenblum, M., Samid, D., Lieberman, F., Terzis, A. J. A., Bjerkvig, R., Laerum, O. D., Arnold, H., Thibault, A., Samid, D., Figg, W. D., Myers, C. E., Reed, E., Thomas, R., Flux, G., Chittenden, S., Doshi, P., Brazil, L., Thomas, D. G. T., Bignor, D., Zalutsky, M., Brada, M., Tjuvajev, Juri, Kaplitt, Michael, Desai, Revathi, Bradley, M. S., Bettie, B. S., Gansbacher, Bernd, Blasberg, Ronald, Haugland, H. K., Saraste, J., Rooseni, K., Laerum, O. D., Vincent, A. J. P. E., Avezaat, C. J. J., Bout, A., Noteboom, J. L., Vecht, C. h., Valerio, D., Hoogerbrugge, P. M., Weber, F., Reszka, R., Zhu, J., Walther, W., List, J., Schulz, W., Wolbers, J. G., Sterenborg, I. I. J. C. M., Kamphorst, W., van Gemert, M. J. C., van Alplien, H. A. M., Salander, P., Bergenheim, T., Henriksson, R., Grant, R., Brazil, L., Thomas, R., Guerrero, D., Laing, R., Ashley, S., Brada, M., Schmidt, B., Bauer, B., Grau, G., Bohnstedt, T., Frydrych, A., Franz, K., Lorenz, R., Brandes, A., Amanzo, P. D'., Zampieri, P., Rigon, A., Scelzi, E., Rotilio, A., Berti, F., Paccagnella, A., Fiorentino, M. V., Müller, B., Krauseneck, P., van Deventer, P. L., Dellemijn, P. L. I., van den Bent, M. J., Vecht, Ch. J., Kansen, P. J., Tredici, G., Petruccioli, N. G., Cavaletti, G., Cavalletti, E., Kiburg, B., Müller, L. J., Moorer-van Delft, C. M., Heimans, J. J., Boer, H. H., Pace, A., Bove, L., Pietrangeli, A., Innocenti, P., Aloe, A., Nardi, M., Jandolo, B., Kellie, S. J., De Graaf, S. S. N., Bloemhof, H., Roebuck, D., Dalla, Pozza L., Uges, D. D. R., Johnston, I., Besser, M., Chaseling, R. A., Koeppen, S., Gründemann, S., Lossos, A., Siegal, T., Nitschke, M., Vieregge, P., Reusche, E., Rob, P., Kömpf, D., Postma, T. J., Vermorken, J. B., Heimans, J. J., Rampling, R. P., Dunlop, D. J., Steward, M. S., Campbell, S. M., Roy, S., Hilkens, P. H. E., Verweij, J., van Putten, W. L. J., Vecht, Ch. J., van den Bent, M. J., Hilkens, P. H. E., Moll, J. W. B., van der Burg, M. E. L., Planting, A. S. T., van Putten, W. L. J., Vecht, Ch. J., van den Bent, M. J., Wondrusch, E., Zifko, U., Drlicek, M., Liszka, U., Grisold, W., Zifko, U., Fazeny, B., Dittrich, Ch., Wondrusch, E., Grisold, W., Verschuuren, Jan J., Meneses, Patricio I., Rosenfeld, Myrna R., Kaplitt, Michael G., Posner, Jerome B., Dalmau, Josep, Sillevis Smitt, P. A. E., Manley, G., Posner, J. B., Cavaletti, G., Bogliun, G., Margorati, L., Bianchi, G., Drlicek, M., Liska, U., Casati, B., Kolig, C., Grisold, H., Graus, F., Reñe, R., Uchuya, M., Valldeoriola, F., Delattre, J. Y., Benedetti de Cosentiro, C., Ortale, D., Martinez, R., Lambre, J., Cagnolati, S., Vinai, C., Salmaggi, A., Nemni, R., Silvani, A., Forno, M. G., Luksch, R., Confalonieri, P., Boiardi, A., Nitschke, M., Scholz, J., Vieregge, P., Kömpf, D., Hochberg, F. H., Pfeiffer, G., Netzer, J., Hansen, Ch., Eggers, Ch., Hagel, Ch., Kunze, K., Verschuuren, Jan J., Rosenblum, Marc K., Lieberman, Frank S., Posner, Jerome B., and Dalmau, Josep
- Published
- 1994
- Full Text
- View/download PDF
12. Hyaluronan and hyaluronectin in the extracellular matrix of human brain tumour stroma
- Author
-
DELPECH, B
- Published
- 1993
- Full Text
- View/download PDF
13. Molecular cloning of a levocabastine-sensitive neurotensin binding site
- Author
-
Chalon, P., Vita, N., Kaghad, M., Guillemot, M., Bonnin, J., Delpech, B., Fur, G. Le, Ferrara, P., and Caput, D.
- Published
- 1996
- Full Text
- View/download PDF
14. Glial fibrillary acidic protein in tumours of the nervous system
- Author
-
Delpech, B, Delpech, A, Vidard, M N, Girard, N, Tayot, J, Clement, J C, and Creissard, P
- Abstract
Glial fibrillary acidic protein (GFA) was assayed in nerve-tumour extracts and located in these tumours by indirect immunofluorescence study. We conclude that GFA is a specific marker of both malignant and normal astrocytes. Non-astrocytic tumours (oligodendroglioma, meningioma) do not contain GFA. Tumours with astrocytic differentiation potential (medulloblastoma) may contain GFA. Comparison of microscopic and GFA assays leads us to conclude that GFA concentration is proportional to the amount of malignant astrocytes in the tumour and inversely proportional to the necrotic area of a tumour. Normal tissue GFA and glioblastoma GFA were found to be immunologically identical.
- Published
- 1978
- Full Text
- View/download PDF
15. An antigen associated with mesenchyme in human tumours that cross-reacts with brain glycoprotein
- Author
-
Delpech, B, Delpech, A, Girard, N, Chauzy, C, and Laumonier, R
- Abstract
Anti-NSA3 antiserum was found to react with many kinds of benign and malignant tumours, as well as foetal skin and intestinal extracts. The corresponding antigens isolated from nervous tissue, benign breast adenoma, and a fibrosarcoma were compared. Immunoprecipitation cannot distinguish between these antigens, and their amino-acid contents were comparable. However, immuno-absorption identified an antigenic determinant that was confined to nervous tissue. Indirect immunofluorescence further confirmed the validity of the concept of a nervous form vs a mesenchymal form of the antigen. Furthermore, immunofluorescence enabled the localization of the antigen found in non-nervous tissue to mesenchyme (mesenchyme-associated antigen: maa), whether the mesenchymal tissue be normal (foetal organs), tumoral (fibrosarcoma) or reactional (connective-tissue stroma of epithelial tumours).
- Published
- 1979
- Full Text
- View/download PDF
16. Hyaluronan: fundamental principles and applications in cancer
- Author
-
DELPECH, B., GIRARD, N., BERTRAND, P., COUREL, M.‐N., CHAUZY, C., and DELPECH, A.
- Abstract
Delpech B, Girard N, Bertrand P, Courel M‐N, Chauzy C, Delpech A (Centre Henri‐Becquerel, Rouen, France). Hyaluronan: fundamental principles and applications in cancer (Minisymposium: Hyaluronan). J Intern Med1997; 242: 41–8.
- Published
- 1997
- Full Text
- View/download PDF
17. Enzyme-Linked Hyaluronectin: A Unique Reagent for Hyaluronan Assay and Tissue Location and for Hyaluronidase Activity Detection
- Author
-
Delpech, B., Bertrand, P., Maingonnat, C., Girard, N., and Chauzy, C.
- Abstract
Several techniques for assaying and localizing hyaluronan (HA), all based on the affinity to hyaluronan of proteins isolated from cartilage, chondrosarcoma, or brain, have been proposed. We show here that a unique reagent, alkaline phosphatase-linked hyaluronectin, can be used to assay hyaluronan in biological fluids or tissue extracts (enzyme-linked sorbent assay method) and to characterize it in cells or tissue sections in two steps: reagent incubation and staining. Results of assays in biological fluids or tissue extracts showed a good correlation with results of the previously described technique using antibodies to detect hyaluronectin bound to a plastic microtest plate (B. Delpech et al., 1985, Anal. Biochem.149, 555-565) for both low concentrations (<1 mg/liter, r= 0.973, P< 0.001) and high concentrations (>1 mg/liter, r= 0.953, P< 0.001). The interassay variations were 8.5% when the assay was performed at 4°C and 18.5% at 37°C. The intraassay variations under those conditions were, respectively, 14.4 and 6.5%. Tissue HA could be detected easily with the reagent, as shown in fetal tissues and in tumors. Specificity of the reaction was controlled either by blocking the reagent with an excess of hyaluronan (which was not possible with other glycosaminoglycans) or by destroying tissue hyaluronan with streptomyces hyaluronidase. Alkaline phosphatase-linked hyaluronectin was also used to assay hyaluronidase activity in several biological fluids. One-hour incubation of hyaluronidase preparations on HA-coated plates made it possible to detect as low as 1 mU bovine testis hyaluronidase and 0.1 mTRU streptomyces hyaluronidase. Four-hour incubation made it possible to detect activity in a 1/12,500 dilution of human serum.
- Published
- 1995
- Full Text
- View/download PDF
18. Molecular cloning of a human β3-adrenergic receptor cDNA
- Author
-
Lelias, J.M., Kaghad, M., Rodriguez, M., Chalon, P., Bonnin, J., Dupre, I., Delpech, B., Bensaid, M., LeFur, G., Ferrara, P., and Caput, D.
- Abstract
We report the molecular cloning of a β3-adrenergic receptor β3-AR cDNA from human brown adipose tissue. The cDNA-encoded protein is identical to the previously cloned β3-AR but with 6 additional amino acids at the C-terminus. The C-terminus is shared by the β3 receptors expressed in human neuroblastoma cells [SK-N-MC] [Mol. Pharmacol. 42 (1992) 964-970]. Furthermore, using a polymerase chain reaction strategy we have cloned and sequenced the β3-AR introns. Sequence analysis demonstrates that the human β3-AR gene comprises at least 3 exons and 2 introns and that the most abundant β3-AR transcripts encode a protein with an exon 3-derived C-terminus. Interestingly, although a similar organization has been found in rodent genes, the rat β3-AR transcripts encode a receptor with an exon 2-derived C-terminus.
- Published
- 1993
- Full Text
- View/download PDF
19. CD44 exon variant 6 epitope and hyaluronate synthase are expressed on HT29 human colorectal carcinoma cells in a SCID mouse model of metastasis formation
- Author
-
Mitchell, Barry, Whitehouse, A., Prehm, P., Delpech, B., and Schumacher, Udo
- Abstract
The factors which lead to the formation of metastases are generally poorly understood; however the expression of a particular variant of the cell adhesion molecule CD44 may be important in facilitating metastasis formation in colon cancer. The aim of the present study was to investigate the expression of CD44 exon v 6 (CD44v6), hyaluronate (one of its ligands), and hyaluronate synthase, in a clinically relevant animal model of metastatic colon carcinoma. HT29 human colon carcinoma cells were injected subcutaneously between the scapulae of severe combined immunodeficient (SCID) mice and left for 3 weeks (by which time the tumours had produced metastases in the lungs). Morphological observations at the tumour-host interface were consistent with the dissociation of neoplastic cells from the primary tumours, and the ability of these cells to migrate through the extracellular matrix facilitating metastasis formation. Immunohistochemically detectable hyaluronate synthase expression was increased in vivocompared with the parent cell line in vitro. CD44v6 expression and hyaluronate were increased around single cells at the periphery of tumours compared with the central regions. CD44v6 and hyaluronate synthase expression were co-expressed in the same cells. Indeed, the present study is the first to demonstrate hyaluronate synthase expression by an epithelial cell type.
- Published
- 1996
- Full Text
- View/download PDF
20. Hyaluronidase production in culture by cells from human tumors
- Author
-
Victor, R., Maingonnat, C., Chauzy, C., Bertrand, P., Olivier, A., Maunoury, R., Gioanni, J., and Delpech, B.
- Published
- 1997
- Full Text
- View/download PDF
21. Molecular cloning of a human β3‐adrenergic receptor cDNA
- Author
-
Lelias, J.M., Kaghad, M., Rodriguez, M., Chalon, P., Bonnin, J., Dupre, I., Delpech, B., Bensaid, M., LeFur, G., Ferrara, P., and Caput, D.
- Abstract
We report the molecular cloning of a β3‐adrenergic receptor β3‐AR cDNA from human brown adipose tissue. The cDNA‐encoded protein is identical to the previously cloned β3‐AR but with 6 additional amino acids at the C‐terminus. The C‐terminus is shared by the β3 receptors expressed in human neuroblastoma cells [SK‐N‐MC] [Mol. Pharmacol. 42 (1992) 964‐970]. Furthermore, using a polymerase chain reaction strategy we have cloned and sequenced the β3‐AR introns. Sequence analysis demonstrates that the human β3‐AR gene comprises at least 3 exons and 2 introns and that the most abundant β3‐AR transcripts encode a protein with an exon 3‐derived C‐terminus. Interestingly, although a similar organization has been found in rodent genes, the rat β3‐AR transcripts encode a receptor with an exon 2‐derived C‐terminus.
- Published
- 1993
- Full Text
- View/download PDF
22. Growth and Differentiation of the Gubernaculum Testis During Testicular Descent in the Pig: Changes in the Extracellular Matrix, Dna Content, and Hyaluronidase, β-Glucuronidase, and β-N-Acetylglucosaminidase Activities
- Author
-
Van Vlissingen, J.M. Fentener, Koch, C.A.M., Delpech, B., and Wensing, C.J.G.
- Abstract
The gubernaculum testis is a loose connective tissue organ that plays an essential mechanical role in testicular descent. In the pig, the first phase of descent (transabdominal migration) is brought about by growth of the gubernaculum through the inguinal canal into the scrotum and simultaneous somatic growth of the fetus. During the second phase the gubernaculum condenses, thus allowing the testis to descend into the scrotum.
- Published
- 1989
- Full Text
- View/download PDF
23. Staining of hyaluronan in rat cerebellum with a hyaluronectin-antihyaluronectin immune complex
- Author
-
Girard, N., Courel, M., Delpech, A., Bruckner, G., and Delpech, B.
- Abstract
The presence of hyaluronan was studied histochemically in the adult rat cerebellum. We used the hyaluronectin-antihyaluronectin immune complex technique based on the high affinity of hyaluronectin for hyaluronan. The immune complex was prepared with hyaluronectin from a human brain extract and an anti-hyaluronectin monoclonal antibody, which does not react with rat hyaluronectin. This is a specific probe for detecting hyaluronan in rat tissues without any reaction for tissue hyaluronectin. Hyaluronan was found at the nodes of Ranvier, in the perineuronal microenvironment of the deep nuclei and at the Purkinje cells surrounding the initial segment of the axon. It was located at the same places as hyaluronectin, in areas specialized in ion exchanges and neurotransmission. This suggests that the hyaluronectin-hyaluronan complex could be involved in these processes. The immune complex technique with anti-hyaluronectin monoclonal antibody thus seems to be a specific and valuable tool for investigations of the distribution of hyaluronan in the rat cerebellum.
- Published
- 1992
- Full Text
- View/download PDF
24. Characterization of hyaluronic acid on tissue sections with hyaluronectin.
- Author
-
Girard, N, Delpech, A, and Delpech, B
- Abstract
An affinity immunological procedure for hyaluronic acid detection on tissue sections is described. This new, sensitive, and specific technique is based on the high affinity of hyaluronectin for hyaluronic acid, utilizing anti-hyaluronectin-hyaluronectin immune complexes. Elimination of binding when the reagent was supplemented with hyaluronic acid or when Streptomyces hyaluronidase-digested tissue sections were used emphasizes the specificity of the assay. This technique made possible accurate HA localization in embryonic mesenchyme, in neural tissue, in kidney medulla, and in tumors.
- Published
- 1986
- Full Text
- View/download PDF
25. Specificity of hyaluronectin binding to hyaluronic acid.
- Author
-
Delpech, B, Bertrand, P, Girard, N, and Delpech, A
- Published
- 1986
- Full Text
- View/download PDF
26. 4.P.52 Effects of diabetes and insulin on hyaluronan, hyaluronectin and CD44 production in injured rat aorta
- Author
-
Chajara, A., Lévesque, H., Chauzy, C., Courel, M.N., Leroy, M., Basuyau, J.P., and Delpech, B.
- Published
- 1997
- Full Text
- View/download PDF
27. Neuroprotection of Excitotoxic Brain Lesions in the Newborn Mouse by Glycine Antagonist and Inhibitor of No °. 159
- Author
-
Marret, S, Gressens, P, Delpech, A, Delpech, B, Fessard, C, and Evrard, P
- Published
- 1996
- Full Text
- View/download PDF
28. 3.P.289 Effect of aging on neointima formation and hyaluronan, hyaluronidase and hyaluronectin production in injured rat aorta
- Author
-
Chajara, A., LlÉvesque, H., Courel, M.N., Leroy, M., Basuyau, J.P., and Delpech, B.
- Published
- 1997
- Full Text
- View/download PDF
29. 3.P.288 Effect of aging on hyaluronan, hyaluronidase and hyaluronectin production in normal rat aorta
- Author
-
Chajara, A., Lévesque, H., Courel, M.N., Leroy, M., Basuyau, J.P., and Delpech, B.
- Published
- 1997
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.