1. Effect of copper sulfate on experimental atherosclerosis
- Author
-
Vlad, Mariana, Bordas, E., Tomus, Rodica, Sava, Doina, Farkas, Ecaterina, and Uza, G.
- Abstract
Serum copper concentration increases significantly (p<0.01) in rats with experimental atherosclerosis compared to a control group. The serum zinc, the zinc, and copper concentration in abdominal aorta and in liver decreases significantly (p<0.05) compared to the control group. Administration of copper sulfate for 100 d in these animals induces a significant increase of serum copper (p<0.01), decrease of serum cholesterol (p<0.05) and increase of liver copper concentration as compared with the group fed only a high cholesterol diet. In the aorta of these animals the copper concentration increases and edema and lipid infiltration are considerably less than in the group of animals fed only a high lipid diet.
- Published
- 1993
- Full Text
- View/download PDF