412 results on '"Bongiorni P"'
Search Results
2. Economic Impact of Ambulatory Clinical Pharmacists in an Advanced Heart Failure Clinic
- Author
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Kido, Kazuhiko, Colvin, Bailey M., Broscious, Rachael, Bongiorni, Sydney, Sokos, George, and Kamal, Khalid M.
- Abstract
Background: Clinical pharmacists play pivotal roles in multidisciplinary heart failure (HF) teams through the management of HF pharmacotherapy, but no study has examined the economic impact of HF ambulatory clinical pharmacists in an advanced HF clinic.Objective: The objective of the study was to evaluate the economic impact of HF ambulatory clinical pharmacist interventions in an advanced HF clinic using a cost-benefit analysis.Methods: This prospective observational study detailed HF ambulatory clinical pharmacist interventions over 6 months in an advanced HF clinic in a single-center tertiary teaching hospital. The economic impact of the interventions was estimated based on the indirect cost savings with pharmacist interventions and direct cost savings recommendations. A cost-benefit analysis was performed to assess the cost of delivering the interventions compared with the benefits generated by clinical pharmacists. Results were reported as a benefit-cost ratio and net benefits.Results: HF ambulatory clinical pharmacists made a total of 2,361 provider-accepted interventions over 6 months. Overall, the 3 most common intervention types were medication reconciliation (28.7%), dose change (20.8%), and addition of medication (12.3%). Anticoagulation (21.2%) was the most common intervened class of medication, followed by sodium-glucose cotransporter-2 inhibitor (12.3%) and angiotensin receptor neprilysin inhibitor (9.2%). The total net benefits were $55,553.24 over 6 months and the benefit-cost ratio was 1.55.Conclusion and Relevance: The addition of cardiology clinical pharmacists to an advanced HF clinic may be financially justified and cost-beneficial.
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- 2022
- Full Text
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3. Is 40 Joules Enough to Successfully Defibrillate With Subcutaneous Implantable Cardioverter-Defibrillators?
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Biffi, Mauro, Bongiorni, Maria Grazia, D’Onofrio, Antonio, Manzo, Michele, Pieragnoli, Paolo, Palmisano, Pietro, Ottaviano, Luca, Perego, Giovanni Battista, Pangallo, Antonio, Lavalle, Carlo, Bonfantino, Vincenzo, Nigro, Gerardo, Landolina, Maurizio Eugenio, Katsouras, Grigorios, Diemberger, Igor, Viani, Stefano, Bianchi, Valter, Lovecchio, Mariolina, Valsecchi, Sergio, and Ziacchi, Matteo
- Abstract
This study evaluated the efficacy of conversion test performed at 40 J (defibrillation margin ≥40 J), and factors potentially associated with test failure were identified.
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- 2021
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4. TIMES, ARE THEY A–CHANGING? IMPLANTATION AND FOLLOW–UP EXPERIENCE WITH LEADLESS PACEMAKERS (MICRA) AT PISA UNIVERSITY HOSPITAL
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Barletta, V, Parlato, A, Tamborrino, P, Parollo, M, Sbragi, S, Canu, A, Di Cori, A, Grifoni, G, Segreti, L, De Lucia, R, Viani, S, Paperini, L, Soldati, E, Bongiorni, M, and Zucchelli, G
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- 2024
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5. Síndrome de muñón arterial vertebral: reporte de un caso y revisión bibliográfica
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Colla Machado, Pedro Ernesto, Buonanotte, María Carla, Bongiorni, Gustavo Walter, Mamani, José Carlos Maria, Buonanotte, Carlos Federico, Colque, Roberto Miguel Angel, Martinez Riera, Leandro, and Pacheco, Guillermo Javier
- Abstract
A diferencia del síndrome de muñón carotídeo, que se halla extensamente descripto en la bibliografía, el síndrome de muñón arterial vertebral es un cuadro infrecuentemente reportado. Acerca del mismo no existe evidencia sólida sobre su mejor tratamiento, pero suele emplearse anticoagulación dada la presunta fisiopatogenia involucrada en la aparición de lesiones isquémicas. Se describe el caso de un paciente con lesiones isquémicas cerebrales de aspecto embólico que presentaba un muñón arterial vertebral en el cual se documentó flujo turbulento en el fondo de saco arterial, motivo por el cual se decidió iniciar anticoagulación oral. Tras 6meses de seguimiento no presentó recurrencia.
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- 2019
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6. Síndrome de amenaza capsular con fluctuaciones relacionadas a cambios de presión arterial tratado con trombólisis endovenosa
- Author
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Colla Machado, Pedro Ernesto, Buonanotte, Carla, Mamani, José Maria, Bongiorni, Gustavo, Sad, Ana Belen, Roca, Federico, Colque, Roberto, and Buonanotte, Federico
- Abstract
El síndrome de amenaza capsular es una forma de presentación de accidente isquémico transitorio infrecuente pero que asocia un elevado riesgo de evolución a accidente cerebrovascular isquémico. No se ha establecido en forma fehaciente su fisiopatogenia, ni existen consensos establecidos acerca del mejor abordaje terapéutico. Se presenta el caso de un paciente con síndrome de amenaza capsular sometido a trombólisis sistémica, y se describe la relación entre fluctuaciones de presión arterial y cambios en el estado clínico. El paciente fue externado tras 5días de internación y presentó una excelente evolución. El uso de trombólisis en este paciente se asoció con una excelente evolución clínica.
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- 2019
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7. Performance and clinical comparison between left ventricular quadripolar and bipolar leads in cardiac resynchronization therapy: Observational research
- Author
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Ziacchi, M., Zucchelli, G., Ricciardi, D., Morani, G., De Ruvo, E., Calzolari, V., Viani, S., Calabrese, V., Tomasi, L., Calò, L., De Mattia, L., Bongiorni, M.G., Boriani, G., and Biffi, M.
- Abstract
To evaluate Attain Performa (Medtronic, Dublin, Ireland) quadripolar lead performance in clinical practice and, secondarily, to compare its long term clinical outcomes vs bipolar leads for left ventricular (LV) pacing.
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- 2018
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8. Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry
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Sawhney, Jitendra PS., Kothiwale, Veerappa A., Bisne, Vikas, Durgaprasad, Rajashekhar, Jadhav, Praveen, Chopda, Manoj, Vanajakshamma, Velam, Meena, Ramdhan, Vijayaraghavan, Govindan, Chawla, Kamaldeep, Allu, Jagan, Pieper, Karen S., John Camm, A., Kakkar, Ajay K., Kakkar, Ajay K., Bassand, Jean-Pierre, John Camm, A., Fitzmaurice, David A., Goldhaber, Samuel Z., Goto, Shinya, Haas, Sylvia, Hacke, Werner, Mantovani, Lorenzo G., Misselwitz, Frank, Pieper, Karen S., Turpie, Alexander G.G., van Eickels, Martin, Verheugt, Freek W.A., John Camm, A., Bassand, Jean-Pierre, Goldhaber, Samuel Z., Haas, Sylvia, Kayani, Gloria, Mantovani, Lorenzo G., Fox, Keith A.A., Gersh, Bernard J., Luciardi, Hector Lucas, Gibbs, Harry, Brodmann, Marianne, Cools, Frank, Barretto, Antonio Carlos Pereira, Connolly, Stuart J., Spyropoulos, Alex, Eikelboom, John, Corbalan, Ramon, Hu, Dayi, Jansky, Petr, Nielsen, Jørn Dalsgaard, Ragy, Hany, Raatikainen, Pekka, Le Heuzey, Jean-Yves, Darius, Harald, Keltai, Matyas, Kakkar, Sanjay, Sawhney, Jitendra Pal Singh, Agnelli, Giancarlo, Ambrosio, Giuseppe, Koretsune, Yukihiro, Sánchez Díaz, Carlos Jerjes, Ten Cate, Hugo, Atar, Dan, Stepinska, Janina, Panchenko, Elizaveta, Lim, Toon Wei, Jacobson, Barry, Oh, Seil, Viñolas, Xavier, Rosenqvist, Marten, Steffel, Jan, Angchaisuksiri, Pantep, Oto, Ali, Parkhomenko, Alex, Al Mahmeed, Wael, Fitzmaurice, David, Goldhaber, Samuel Z., Hu, D.Y., Chen, K.N., Zhao, Y.S., Zhang, H.Q., Chen, J.Z., Cao, S.P., Wang, D.W., Yang, Y.J., Li, W.H., Yin, Y.H., Tao, G.Z., Yang, P., Chen, Y.M., He, S.H., Wang, Ying, Wang, Yong, Fu, G.S., Li, X., Wu, T.G., Cheng, X.S., Yan, X.W., Zhao, R.P., Chen, M.S., Xiong, L.G., Chen, P., Jiao, Y., Guo, Y., Xue, L., Wang, F.Z., Li, H., Yang, Z.M., Bai, C.L., Chen, J., Chen, J.Y., Chen, X., Feng, S., Fu, Q.H., Gao, X.J., Guo, W.N., He, R.H., He, X.A., Hu, X.S., Huang, X.F., Li, B., Li, J., Li, L., Li, Y.H., Liu, T.T., Liu, W.L., Liu, Y.Y., Lu, Z.C., Luo, X.L., Ma, T.Y., Peng, J.Q., Sheng, X., Shi, X.J., Sun, Y.H., Tian, G., Wang, K., Wang, L., Wu, R.N., Xie, Q., Xu, R.Y., Yang, J.S., Yang, L.L., Yang, Q., Yang, Y.J., Ye, Y., Yu, H.Y., Yu, J.H., Yu, T., Zhai, H., Zhan, Q., Zhang, G.S., Zhang, Q., Zhang, R., Zhang, Y., Zheng, W.Y., Zhou, B., Zhou, Z.H., Zhu, X.Y., Kakkar, S., Sawhney, J.P.S., Jadhav, P., Durgaprasad, R., Ravi Shankar, A.G., Rajput, R.K., Bhargava, K., Sarma, R., Srinivas, A., Roy, D., Nagamalesh, U.M., Chopda, M., Kishore, R., Kulkarni, G., Chandwani, P., Pothiwala, R.A., Padinhare Purayil, M., Shah, S., Chawla, K., Kothiwale, V.A., Raghuraman, B., Vijayaraghavan, G., Vijan, V.M., Bantwal, G., Bisne, V., Khan, A., Gupta, J.B., Kumar, S., Jain, D., Abraham, S., Adak, D., Barai, A., Begum, H., Bhattacharjee, P., Dargude, M., Davies, D., Deshpande, B., Dhakrao, P., Dhyani, V., Duhan, S., Earath, M., Ganatra, A., Giradkar, S., Jain, V., Karthikeyan, R., Kasala, L., Kaur, S., Krishnappa, S., Lawande, A., Lokesh, B., Madarkar, N., Meena, R., More, P., Naik, D., Prashanth, K., Rao, M., Rao, N.M., Sadhu, N., Shah, D., Sharma, M., Shiva, P., Singhal, S., Suresh, S., Vanajakshamma, V., Panse, S.G., Koretsune, Y., Kanamori, S., Yamamoto, K., Kumagai, K., Katsuda, Y., Sadamatsu, K., Toyota, F., Mizuno, Y., Misumi, I., Noguchi, H., Ando, S., Suetsugu, T., Minamoto, M., Oda, Hiroshi, Shiraishi, K., Adachi, S., Chiba, K., Norita, H., Tsuruta, M., Koyanagi, T., Yamamoto, K., Ando, H., Higashi, T., Okada, K., Azakami, S., Komaki, S., Kumeda, K., Murayama, T., Matsumura, J., Oba, Y., Sonoda, R., Goto, K., Minoda, K., Haraguchi, Y., Suefuji, H., Miyagi, H., Kato, H., Nakamura, Tadashi, Nakamura, Tsugihiro, Nandate, H., Zaitsu, R., Fujiura, Yoshihisa, Yoshimura, A., Numata, H., Ogawa, J., Tatematsu, H., Kamogawa, Y., Murakami, K., Wakasa, Y., Yamasawa, M., Maekawa, H., Abe, S., Kihara, H., Tsunoda, S., Saito, Katsumi, Saito, Kazuyuki, Fudo, T., Obunai, K., Tachibana, H., Oba, I., Kuwahata, T., Higa, S., Gushiken, M., Eto, T., Yoshida, H., Ikeda, D., Fujiura, Yoshitake, Ishizawa, M., Nakatsuka, M., Murata, K., Ogurusu, C., Shimoyama, M., Akutsu, M., Takamura, I., Hoshino, F., Yokota, N., Iwao, T., Tsuchida, K., Takeuchi, M., Hatori, Y., Kitami, Y., Nakamura, Yoichi, Oyama, R., Ageta, M., Oda, Hiroyuki, Go, Y., Mishima, K., Unoki, T., Morii, S., Shiga, Yuhei, Sumi, H., Nagatomo, T., Sanno, K., Fujisawa, K., Atsuchi, Y., Nagoshi, T., Seto, T., Tabuchi, T., Kameko, M., Nii, K., Oshiro, K., Takezawa, H., Nagano, S., Miyamoto, N., Iwaki, M., Nakamura, Yuichiro, Fujii, M., Okawa, M., Abe, Masahiko, Abe, Masatake, Abe, Mitsunori, Saito, T., Mito, T., Nagao, K., Minami, J., Mita, T., Sakuma, I., Taguchi, T., Marusaki, S., Doi, H., Tanaka, M., Fujito, T., Matsuta, M., Kusumoto, T., Kakinoki, S., Ashida, K., Yoshizawa, N., Agata, J., Arasaki, O., Manita, M., Ikemura, M., Fukuoka, S., Murakami, H., Matsukawa, S., Hata, Y., Taniguchi, T., Ko, T., Kubo, H., Imamaki, M., Akiyama, M., Inagaki, M., Odakura, H., Ueda, T., Katsube, Y., Nakata, A., Watanabe, H., Techigawara, M., Igarashi, M., Taga, K., Kimura, T., Tomimoto, S., Shibuya, M., Nakano, M., Ito, K., Seo, T., Hiramitsu, S., Hosokawa, H., Hoshiai, M., Hibino, M., Miyagawa, K., Horie, Hajime, Sugishita, N., Shiga, Yukio, Soma, A., Neya, K., Yoshida, Tetsuro, Yoshida, Tomoki, Mizuguchi, M., Ishiguro, M., Minagawa, T., Wada, M., Mukawa, H., Okuda, F., Nagasaka, S., Abe, Y., Adachi, Sen, Adachi, Susumu, Adachi, T., Akahane, K., Amano, T., Aoki, K., Aoyama, T., Arai, H., Arima, S., Arino, T., Asano, H., Asano, T., Azuma, J., Baba, T., Betsuyaku, T., Chibana, H., Date, H., Doiuchi, J., Emura, Y., Endo, M., Fujii, Y., Fujiki, R., Fujisawa, A., Fujisawa, Y., Fukuda, T., Fukui, T., Furukawa, N., Furukawa, T., Furumoto, W., Goto, T., Hamaoka, M., Hanazono, N., Hasegawa, K., Hatsuno, T., Hayashi, Y., Higuchi, K., Hirasawa, K., Hirayama, H., Hirose, M., Hirota, S., Honda, M., Horie, Hideki, Ido, T., Iiji, O., Ikeda, H., Ikeda, K., Ikeoka, K., Imaizumi, M., Inaba, H., Inoue, T., Iseki, F., Ishihara, A., Ishioka, N., Ito, N., Iwase, T., Kakuda, H., Kamata, J., Kanai, H., Kanda, H., Kaneko, M., Kano, H., Kasai, T., Kato, T., Kato, Y., Kawada, Y., Kawai, K., Kawakami, K., Kawakami, S., Kawamoto, T., Kawano, S., Kim, J., Kira, T., Kitazawa, H., Kitazumi, H., Kito, T., Kobayashi, T., Koeda, T., Kojima, J., Komatsu, H., Komatsu, I., Koshibu, Y., Kotani, T., Kozuka, T., Kumai, Y., Kumazaki, T., Maeda, I., Maeda, K., Maruyama, Y., Matsui, S., Matsushita, K., Matsuura, Y., Mineoi, K., Mitsuhashi, H., Miura, N., Miyaguchi, S., Miyajima, S., Miyamoto, H., Miyashita, A., Miyata, S., Mizuguchi, I., Mizuno, A., Mori, T., Moriai, O., Morishita, K., Murai, O., Nagai, Sho, Nagai, Shunichi, Nagata, E., Nagata, H., Nakagomi, A., Nakahara, S., Nakamura, M., Nakamura, R., Nakanishi, N., Nakayama, T., Nakazato, R., Nanke, T., Nariyama, J., Niijima, Y., Niinuma, H., Nishida, Y., Nishihata, Y., Nishino, K., Nishioka, H., Nishizawa, K., Niwa, I., Nomura, K., Nomura, S., Nozoe, M., Ogawa, T., Ohara, N., Okada, M., Okamoto, K., Okita, H., Okuyama, M., Ono, H., Ono, T., Onuki Pearce, Y., Oriso, S., Ota, A., Otaki, E., Saito, Y., Sakai, H., Sakamoto, N., Sakamoto, Y., Samejima, Y., Sasagawa, Y., Sasaguri, H., Sasaki, A., Sasaki, T., Sato, Kazuki, Sato, Kiyoharu, Sawano, M., Seki, S., Sekine, Y., Seta, Y., Sezaki, K., Shibata, N., Shiina, Y., Shimono, H., Shimoyama, Y., Shindo, T., Shinohara, H., Shinohe, R., Shinozuka, T., Shirai, T., Shiraiwa, T., Shozawa, Y., Suga, T., Sugimoto, C., Suzuki, Kazuo, Suzuki, Keita, Suzuki, Shu, Suzuki, Shunji, Suzuki, Susumu, Suzuki, Y., Tada, M., Taguchi, A., Takagi, T., Takagi, Y., Takahashi, K., Takahashi, S., Takai, H., Takanaka, C., Take, S., Takeda, H., Takei, K., Takenaka, K., Tana, T., Tanabe, G., Taya, K., Teragawa, H., Tohyo, S., Toru, S., Tsuchiya, Y., Tsuji, T., Tsuzaki, K., Uchiyama, H., Ueda, O., Ueda, T., Ueyama, Y., Wakaki, N., Wakiyama, T., Washizuka, T., Watanabe, M., Yamada, T., Yamagishi, T., Yamaguchi, H., Yamamoto, Kenichi, Yamamoto, Kentaro, Yamamoto, Kunihiko, Yamamoto, T., Yamaura, M., Yamazoe, M., Yasui, K., Yokoyama, Y., Yoshida, K., Lim, T.W., Ching, C.K., Foo, C.G., Chow, J.H., Chen, D.D., Jaufeerally, F.R., Lee, Y.M., Li, H., Lim, G., Lim, W.T., Thng, S., Yap, S.Y., Yeo, C., Oh, S., Pak, H.N., Kim, J.-B., Kim, J.H., Jang, S.-W., Kim, D.H., Kim, J., Ryu, D.R., Park, S.W., Kim, D.-K., Choi, D.J., Oh, Y.S., Cho, M.-C., Kim, S.-H., Jeon, H.-K., Shin, D.-G., Park, J.S., Park, H.K., Han, S.-J., Sung, J.H., Cho, J.-G., Nam, G.-B., On, Y.K., Lim, H.E., Kwak, J.J., Cha, T.-J., Hong, T.J., Park, S.H., Yoon, J.H., Kim, N.-H., Kim, K.-S., Jung, B.C., Hwang, G.-S., Kim, C.-J., Park, J.S., Kim, D.B., Ahn, J.J., An, H.J., Bae, H., Baek, A.L., Chi, W.J., Choi, E.A., Choi, E.H., Choi, H.K., Choi, H.S., Han, S., Heo, E.S., Her, K.O., Hwang, S.W., Jang, E.M., Jang, H.-S., Jang, S., Jeon, H.-G., Jeon, S.R., Jeon, Y.R., Jeong, H.K., Jung, I.-A., Kim, Hyeon Jeong, Kim, Hyun Ju, Kim, Ji Seon, Kim, Jung Sook, Kim, J.A., Kim, K.T., Kim, M.S., Kim, Sang Hee, Kim, Sang Hyun, Kim, Y.-I., Lee, C.S., Lee, E.H., Lee, G.H., Lee, H.Y., Lee, H.-Y., Lee, K.H., Lee, K.R., Lee, M.S., Lee, M.-Y., Lee, R.W., Lee, S.E., Lee, S.H., Lee, S., Lee, W.Y., Noh, I.K., Park, A.R., Park, B.R., Park, H.N., Park, J.H., Park, M., Park, Y., Seo, S.-Y., Shim, J., Sim, J.H., Sohn, Y.M., Son, W.S., Son, Y.S., Song, H.J., Wi, H.K., Woo, J.J., Ye, S., Yim, K.H., Yoo, K.M., Yoon, E.J., Yun, S.Y., Angchaisuksiri, P., Chawanadelert, S., Mongkolwongroj, P., Kanokphatcharakun, K., Cheewatanakornkul, S., Laksomya, T., Pattanaprichakul, S., Chantrarat, T., Rungaramsin, S., Silaruks, S., Wongcharoen, W., Siriwattana, K., Likittanasombat, K., Katekangplu, P., Boonyapisit, W., Cholsaringkarl, D., Chatlaong, B., Chattranukulchai, P., Santanakorn, Y., Hutayanon, P., Khunrong, P., Bunyapipat, T., Jai-Aue, S., Kaewsuwanna, P., Bamungpong, P., Gunaparn, S., Hongsuppinyo, S., Inphontan, R., Khattaroek, R., Khunkong, K., Kitmapawanont, U., Kongsin, C., Naratreekoon, B., Ninwaranon, S., Phangyota, J., Phrommintikul, A., Phunpinyosak, P., Pongmorakot, K., Poomiphol, S., Pornnimitthum, N., Pumprueg, S., Ratchasikaew, S., Sanit, K., Sawanyawisuth, K., Silaruks, B., Sirichai, R., Sriwichian, A., Suebjaksing, W., Sukklad, P., Suttana, T., Tangsirira, A., Thangpet, O., Tiyanon, W., Vorasettakarnkij, Y., Wisaratapong, T., Wongtheptien, W., Wutthimanop, A., Yawila, S., Oto, A., Altun, A., Ozdogru, I., Ozdemir, K., Yilmaz, O., Aydinlar, A., Yilmaz, M.B., Yeter, E., Ongen, Z., Cayli, M., Pekdemir, H., Ozdemir, M., Sucu, M., Sayin, T., Demir, M., Yorgun, H., Ersanli, M., Okuyan, E., Aras, D., Abdelrahman, H., Aktas, O., Alpay, D., Aras, F., Bireciklioglu, M.F., Budeyri, S., Buyukpapuc, M., Caliskan, S., Esen, M., Felekoglu, M.A., Genc, D., Ikitimur, B., Karaayvaz, E.B., Kılıç Karataş, S., Okutucu, S., Ozcelik, E., Quisi, A., Sag, H., Sahiner, L., Sayin, B.Y., Seker, T., Uzun Alkan, D., Yildirim, E., Yildirim, R., Yilmaz, F., Yuksekdag, V., Luciardi, H.L., Vensentini, N., Ingaramo, A.C., Sambadaro, G.A., Fernandez Caputi, V., Berman, S.G., Dragotto, P., Kleiban, A.J., Centurion, N., Giacomi, G., Ahuad Guerrero, R.A., Conde, D., Zapata, G., Di Paola, L.A., Ramos, J.L., Dran, R.D., Egido, J., Fernandez, A.A., Fosco, M.J., Sassone, S., Sinisi, V.A., Cartasegna, L.R., Berli, M.A., Gomez Vilamajo, O.A., Ferroni, F., Alaguibe, E.D., Alvarez D'Amelio, A., Arabetti, C., Arias, L., Belardi, J.A., Bergesio, L., Berli, F., Berli, M., Borchowiec, S., Buzzetti, C., Cabrini, R., Campisi, V., Cappi, A.L., Carrizo, R., Colombo Berra, F., Costabel, J.P., Costamagna, O.J.A., Damonte, A.A., De Urquiza, I.N., Diez, F., Edén, M.F., Fanuele, M., Fernandez Voena, F., Foa Torres, M., Funosas, C., Giacomi, M.P., Gimenez, C.H., Gurfinkel, E.P., de L.M. Had, M., Hansen, V., Hrabar, A.D., Ingratta, M., Lopez, A., Maehara, G., Maffei, L., Martinelli, A., Martinelli, C., Matkovich, J., Mautner, B., Meirino, A., Munguia, R., Navarro, A., Novas, V., Perez Prados, G., Pontoriero, J., Potito, R.N., Ricotti, C., Rodriguez, M.A., Rolandi, F., Said Palladino, M.E., Salinger, M., Sanziani, L.S., Schygiel, P.O., Sossich, A., Tinto, J.F., Tonelli, L., Tufare, A.L., Vallejo, M., Yunis, M.E., Zillo, M., Zurbrigk, F.J., Barretto, A.C.P., Sobral Filho, D.C., Jaber, J., Armaganijan, D., Faria Neto, J., Steffens, A., Kunz Sebba Barroso de Souza, W., de Souza Neto, J.D., Ribeiro, J.M., Silveira Teixeira, M., Ferreira Rossi, P.R., Pires, L., Moreira, D., Moura Jorge, J.C., Menezes Lorga Filho, A., Bodanese, L.C., Westerlund Montera, M., Del Carlo, C.H., Da Rocha Rodrigues, T., Alves da Costa, F.A., Lopes, A., Lopes, R., Araújo, G.R., Fernandes Manenti, E.R., Kerr Saraiva, J.F., Ferreira Braga, J.C., Negri, A., Souto, L., Moncada, C., Bertolim Precoma, D., Roquette, F., Reis, G., Ramos Filho, R.A., Lanna Figueiredo, E., Vieira Botelho, R., Munhoz da Fontoura Tavares, C., Costantini Frack, C.R., Abdalla Saad, J., Finimundi, H.C., Pisani, C., Chemello, D., Pereira Martins, M., Broilo França, C.C., Alban, F., Aranha Rosito, G.B., de Moura Xavier Moraes Junior, J.B., Tumelero, R.T., Nigro Maia, L., Simões de Almeida, R., do Carmo Borges, N.C., Gomes Ferreira, L.G., Agliardi, P., Alves de Oliveira Gomes, J., Araujo, V., Arruda Nakazone, M., Barbosa, T., Barroso, S., Belisario Falchetto, E., Bellotti Lopes, H., Benez Teixeira Lemos, M.A., Biazus, G., Borges Queiroz, L., Camazzola, F.E., Caporale, M., Cardoso Boscato, S., Chieza, F., Chokr, M.O., Clemente Mingireanov, R., Codonho Góes, N., Correa, C., Costa, M., Costantini Ortiz, C., da Silva, L.S., da Silva Paulitsch, F., da Silveira, J.A., Daros, E., de Araújo, G.R., Del Monaco, M.I., Dias, C., Dias, M.A., Drummond Wainstein, A.P., Ely Pizzato, P., Esteves, D.C., Fabri, P., Félix Lorenzato 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Robertson, C., Sage, A., Sanghera, T., Shaw, P., Shoemaker, J., Smith, K., Stephanie, B., Thatcher, A., Theobald, H., Thompson, N., Treasure, L., Tripti, T., Verdi, C., and Worthy, V.
- Abstract
The Global Anticoagulant Registry in the FIELD–Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry.
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- 2018
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9. Missense mutations of NCPAG gene affect calving ease in Piedmontese cattle: preliminary evidences
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Chillemi, Giovanni, Bongiorni, Silvia, Gioiosa, Silvia, Flati, Tiziano, Castrignanò, Tiziana, Milanesi, Marco, Ajmone Marsan, Paolo, and Valentini, Alessio
- Abstract
AbstractA previous genome scan on 323 Piedmontese individuals identified a cluster of 13 SNPs significantly associated with direct calving ease and centred on the three genes LAP3, LCORL and NCAPG in chromosome 6. We investigated missense mutations affecting calving ease in Piedmontese cattle in the identified region using sequences from the whole exome in eight Piedmontese individuals chosen from the extremes of the direct calving ease estimated breeding values distribution for this trait. The present study has not found missense variants in LAP3 and LCORL, while two were identified on NCAPG by three different variant calling methods. Other gene candidates in the same region harbour missense mutations, such as PPM1K, PKD2, SPP1 and MEPE, but both SIFT analysis and chi-square test on frequency of alleles make us hypothesise that NCAPG is the single gene responsible for the trait variation. The two SNPs on NCAPG are in complete linkage disequilibrium in our samples; therefore, further investigations are needed in order to discriminate their role.
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- 2018
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10. Decompressive craniotomy for the treatment of malignant infarction of the middle cerebral artery: mortality and outcome
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Bongiorni, Gianise Toboliski, Hockmuller, Marjeane Cristina Jaques, Klein, Cristini, and Antunes, Ápio Cláudio Martins
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- 2017
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11. P447 TRANSCATHETER PACING SYSTEM IMPLANT: IS IT A MATTER OF GENDER?
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Barletta, V, Lepone, A, Tamborrino, P, Parlato, A, Parollo, M, Mazzocchett, L, Sbragi, S, Canu, A, Di Cori, A, De Lucia, R, Segreti, L, Bongiorni, M, and Zucchelli, G
- Published
- 2023
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12. Design and Rationale of the Modular ATP Global Clinical Trial: A Novel Intercommunicative Leadless Pacing System and the Subcutaneous Implantable Cardioverter Defibrillator
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Lloyd, Michael S., Brisben, Amy J., Reddy, Vivek Y., Blomström-Lundqvist, Carina, Boersma, Lucas VA., Bongiorni, Maria Grazia, Burke, Martin C., Cantillon, Daniel J., Doshi, Rahul, Friedman, Paul A., Gras, Daniel, Kutalek, Steven P., Neuzil, Petr, Roberts, Paul R., Wright, D.J., Appl, Ursula, West, Julie, Carter, Nathan, Stein, Kenneth M., Mont, Lluis, and Knops, Reinoud E.
- Abstract
The subcutaneous implantable cardioverter/defibrillator (S-ICD) has demonstrated safety and efficacy for the treatment of malignant ventricular arrhythmias. However, a limitation of the S-ICD lies in the inability to either pace-terminate ventricular tachycardia or provide prolonged bradycardia pacing support.
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- 2023
- Full Text
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13. Group Versus Individual Physical Therapy for Veterans With Knee Osteoarthritis: Randomized Clinical Trial
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Allen, Kelli D., Bongiorni, Dennis, Bosworth, Hayden B., Coffman, Cynthia J., Datta, Santanu K., Edelman, David, Hall, Katherine S., Lindquist, Jennifer H., Oddone, Eugene Z., and Hoenig, Helen
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- 2016
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14. Michael Haneke’s Amourin the Light of italian neorealism
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Bongiorni, Kevin
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Abstract:This article examines Haneke’s 2012 film Amourwithin the framework of the tenets of Italian neorealism. It is argued that if we look closely at Cesare Zavattini’s critical ideas behind Italian neorealism, and Vittorio De Sica’s implementation of these ideas—in a film like The Bicycle Thief—we will find that, for a number of reasons, the principles of neorealism are, in fact, compromised. The article suggests that upon scrutiny, Amouris in many ways as “true” to the principles of Italian neorealism as the Italians were. And, in fact, in some ways it is even more “true” to those principles.
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- 2016
15. Guía ESC 2015 sobre el tratamiento de la endocarditis infecciosa
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Habib, Gilbert, Lancellotti, Patrizio, Antunes, Manuel J., Bongiorni, Maria Grazia, Casalta, Jean-Paul, Zotti, Francesco del, Dulgheru, Raluca, Khoury, Gebrine El, Erba, Paola Anna, Iung, Bernard, Miró, Jose M., Mulder, Barbara J., Plonska-Gosciniak, Edyta, Price, Susanna, Roos-Hesselink, Jolien, Snygg-Martin, Ulrika, Thuny, Franck, Mas, Pilar Tornos, Vilacosta, Isidre, Zamorano, José Luis, Erol, Çetin, Nihoyannopoulos, Petros, Aboyans, Victor, Agewall, Stefan, Athanassopoulos, George, Aytekin, Saide, Benzer, Werner, Bueno, Héctor, Broekhuizen, Lidewij, Carerj, Scipione, Cosyns, Bernard, de Backer, Julie, de Bonis, Michele, Dimopoulos, Konstantinos, Donal, Erwan, Drexel, Heinz, Flachskampf, Frank Arnold, Hall, Roger, Halvorsen, Sigrun, Hoen, Bruno, Kirchhof, Paulus, Lainscak, Mitja, Leite-Moreira, Adelino F., Lip, Gregory Y.H., Mestres, Carlos A., Piepoli, Massimo F., Punjabi, Prakash P., Rapezzi, Claudio, Rosenhek, Raphael, Siebens, Kaat, Tamargo, Juan, and Walker, David M.
- Abstract
Se puede consultar en el apéndice las filiaciones de los coordinadores de sección.
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- 2016
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16. Silence Is Golden: An Uncommon Case of Vocalization-Triggered Atrial Tachycardia
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Zucchelli, Giulio, Coluccia, Giovanni, Di Cori, Andrea, Soldati, Ezio, and Bongiorni, Maria Grazia
- Abstract
Vocalization-related atrial tachyarrhythmias are extremely rare. We describe the case of a young woman in whom speaking was proven to be the trigger of a nearly incessant right atrial tachycardia, poorly controlled with medical therapy and successfully treated with catheter ablation. The identification of the trigger was pivotal for mapping and ablation, providing a reliable means to assess the success of the procedure.
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- 2014
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17. C1 THE ROLE OF ATRIAL ELECTRO–MECHANICAL COUPLING AS PREDICTOR OF CATHETER ABLATION EFFICIENCY
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Barletta, V, Spatafora, D, Gentile, F, Parollo, M, Mazzocchetti, L, Zucchelli, G, and Bongiorni, M
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- 2022
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18. Port-a-Cath Complicated by Infection or Migration Not Removed by Manual Traction: Usefulness of Cardiac Pacing Leads Extraction Techniques
- Author
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De Lucia, Raffaele, Segreti, Luca, Soldati, Ezio, Di Cori, Andrea, Zucchelli, Guilio, and Bongiorni, Maria G.
- Abstract
Long-term use of Port-a-Caths (PACs) is related to device-related delayed complications. The aim of this study is to describe the high success rate and safety of cardiac pacing lead extraction techniques used for PACs complicated by infection or migration and not removed by manual traction.
- Published
- 2013
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19. Rationale and design of the NO-PARTY trial: near-zero fluoroscopic exposure during catheter ablation of supraventricular arrhythmias in young patients
- Author
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Casella, Michela, Dello Russo, Antonio, Pelargonio, Gemma, Bongiorni, Maria Grazia, Del Greco, Maurizio, Piacenti, Marcello, Andreassi, Maria Grazia, Santangeli, Pasquale, Bartoletti, Stefano, Moltrasio, Massimo, Fassini, Gaetano, Marini, Massimiliano, Di Cori, Andrea, Di Biase, Luigi, Fiorentini, Cesare, Zecchi, Paolo, Natale, Andrea, Picano, Eugenio, and Tondo, Claudio
- Abstract
AbstractIntroductionRadiofrequency catheter ablation is the mainstay of therapy for supraventricular tachyarrhythmias. Conventional radiofrequency catheter ablation requires the use of fluoroscopy, thus exposing patients to ionising radiation. The feasibility and safety of non-fluoroscopic radiofrequency catheter ablation has been recently reported in a wide range of supraventricular tachyarrhythmias using the EnSite NavX™ mapping system. The NO-PARTY is a multi-centre, randomised controlled trial designed to test the hypothesis that catheter ablation of supraventricular tachyarrhythmias guided by the EnSite NavX™ mapping system results in a clinically significant reduction in exposure to ionising radiation compared with conventional catheter ablation.MethodsThe study will randomise 210 patients undergoing catheter ablation of supraventricular tachyarrhythmias to either a conventional ablation technique or one guided by the EnSite NavX™ mapping system. The primary end-point is the reduction of the radiation dose to the patient. Secondary end-points include procedural success, reduction of the radiation dose to the operator, and a cost-effectiveness analysis. In a subgroup of patients, we will also evaluate the radiobiological effectiveness of dose reduction by assessing acute chromosomal DNA damage in peripheral blood lymphocytes.ConclusionsNO-PARTY will determine whether radiofrequency catheter ablation of supraventricular tachyarrhythmias guided by the EnSite NavX™ mapping system is a suitable and cost-effective approach to achieve a clinically significant reduction in ionising radiation exposure for both patient and operator.
- Published
- 2012
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20. Efficacy of Low Interatrial Septum and Right Atrial Appendage Pacing for Prevention of Permanent Atrial Fibrillation in Patients With Sinus Node Disease
- Author
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Verlato, Roberto, Botto, Giovanni Luca, Massa, Riccardo, Amellone, Claudia, Perucca, Antonello, Bongiorni, Maria Grazia, Bertaglia, Emanuele, Ziacchi, Vigilio, Piacenti, Marcello, Del Rosso, Attilio, Russo, Giovanni, Baccillieri, Maria Stella, Turrini, Pietro, and Corbucci, Giorgio
- Abstract
The role of pacing sites and atrial electrophysiology on the progression of atrial fibrillation (AF) to the permanent form in patients with sinus node dysfunction (SND) has never been investigated. The aim of the study was to investigate the relationship between atrial electrophysiology and the efficacy of atrial pacing at the low interatrial septum (IAS) or at the right atrial appendage (RAA) to prevent persistentpermanent AF in patients with SND.
- Published
- 2011
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21. Fibrinolytic and coagulation pathways after laparoscopic and open surgery: a prospective randomized trial
- Author
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Tsiminikakis, Nikos, Chouillard, Elie, Tsigris, Christos, Diamantis, Theodoros, Bongiorni, Christine, Ekonomou, Constantinos, Antoniou, C., and Bramis, Ioannis
- Abstract
Abstract: Background: Tissue injury poses increased risk for postoperative thromboembolic complications. Laparoscopic surgery, by causing limited tissue injury, is associated with lower risk for thromboembolism than is open surgery. We conducted a prospective randomized study in order to detect potentially existing differences in activation of coagulation and fibrinolytic pathways between open and laparoscopic surgery. Methods: Forty patients with chronic cholelithiasis were randomly assigned to undergo open (group A) or laparoscopic cholecystectomy (group B). Blood samples were taken preoperatively, at the end of the procedure, and at 24 and 72 h postoperatively. Prothrombin time (PT), activated partial thromboplastin time (APTT), international normalized ratio (INR), platelets (PLT), soluble fibrin monomer complexes (F.S. test), fibrin degradation products (FDP), D-dimers (D-D), and fibrinogen (FIB) were measured and compared within each group and between groups: Thrombin–antithrombin complexes (TAT) and prothrombin fragments (F1 + 2) were measured at 24 and 72 h postoperatively. Results: Demographics were comparable between groups. Immediately postoperatively, TAT and F1 + 2 were significantly higher in group A (p < 0.05). They also increased significantly postoperatively as compared with preoperative levels within each group (p < 0.05). D-dimers were significantly higher in group A (p < 0.01) immediately postoperatively. D-dimers also increased significantly postoperatively in group B as compared with preoperative levels (p < 0.001). FIB decreased slightly in both groups at 24 h postoperatively but there was a significant increase in group A (p < 0.01). Soluble fibrin monomer complexes (SFMC) were detected twice in group A and only once in group B. FDP levels over 5 μg/ml were detected more often in group A (p < 0.05). There was not any case of thromboembolism or abnormal bleeding. Conclusions: Open surgery leads to higher activation of the clotting system than do laparoscopic procedures. Although of a lower degree, hypercoagulability is still observed in patients undergoing laparoscopic surgery and therefore routine thromboembolic prophylaxis should be considered.
- Published
- 2009
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22. Early Left Ventricular Structural Myocardial Alterations and Their Relationship with Functional and Electrical Properties of the Heart in Myotonic Dystrophy Type 1
- Author
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Di Cori, Andrea, Bongiorni, Maria Grazia, Zucchelli, Giulio, Soldati, Ezio, Falorni, Michela, Segreti, Luca, Gemignani, Cristina, Siciliano, Alberto, Bovenzi, Francesco Maria, and Di Bello, Vitantonio
- Published
- 2009
- Full Text
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23. Management of Cardiac Device Infections: A Retrospective Survey of a Non-Surgical Approach Combining Antibiotic Therapy with Transvenous Removal
- Author
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Tascini, C., Bongiorni, M.G., Gemignani, G., Soldati, E., Leonildi, A., Arena, G., Doria, R., Giannola, G., La Pira, F., Tagliaferri, E., Caravelli, P., Dell'anna, R., and Menichetti, F.
- Abstract
AbstractPacemakers (PMs) and implantable cardioverter defibrillators (ICDs) have become life-saving therapeutic tools for patients with cardiac arrhythmia. Complications include thrombosis, embolism and infections at a highly variable rate. Surgical removal of the infected device has been perceived as the only way to guarantee a successful outcome and to reduce the high risk of mortality. Recently, a transvenous extraction method has been developed to remove infected intracardiac leads without sternotomy. This survey was designed to evaluate the outcome of an approach combining antibiotic therapy with non-surgical transvenous complete removal for the management of cardiac device infections (CDIs).We reviewed case-histories of 121 patients (105 with PM and 16 with ICD infections). The aim of our retrospective survey was to ascertain that a non-invasive transvenous complete removal of the infected devices is safe and effective when associated with appropriate antibiotic therapy starting 10 days before the procedure and extending to at least three weeks after.The infected devices were successfully removed in all patients with a non-surgical transvenous technique. The infections were most frequently caused by coagulase-negative staphylococci (70%) Staphylococcus aureus(14%), and Gram-negative rods (12%). Polymicrobial infections were documented in 19 patients and represent 16% of all device-related infections. The removal of the devices was done during antibiotic therapy, administered for a median of 26 days (range 23 to 45 days). Neither fatalities nor relapse of infections were recorded in the patient population during the one-year follow-up visits.According to our experience, CDIs can be treated with antibiotic therapy and non-surgical removal of the entire infected device, thus allowing a successful reimplantation. This procedure prevents recurrent infections and operative mortality.
- Published
- 2006
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24. The new rules of networking.
- Author
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Bongiorni, Sara
- Subjects
SOCIAL networks ,BUSINESS ,TIME management ,ASSOCIATIONS, institutions, etc. - Abstract
Focuses on the evolution of networking. Significance of networking as a component in doing business; Importance of time management in networking; Establishment of organizations with an emphasis on networking.
- Published
- 2005
25. New-Onset Ventricular Tachycardia After Cardiac Resynchronization Therapy
- Author
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Cori, Andrea, Bongiorni, Maria, Arena, Giuseppe, Soldati, Ezio, Giannola, Gabriele, Zucchelli, Giulio, and Balbarini, Alberto
- Abstract
It is well established that coronary artery disease with healed myocardial infarction is the most common backdrop for ventricular tachycardia (VT). Although the clinical benefits of biventricular pacing (BivP) in the treatment of severe heart failure are well documented, exact relation with ventricular arrhythmias remains still unclear. We describe a case of a patient, whitout a previous history of arrhythmic episodes, in which the onset of several episodes of VT presented immediatly after cardiac resynchronization therapy (CRT) and did not occur after BivP discontinuation.
- Published
- 2005
- Full Text
- View/download PDF
26. New-Onset Ventricular Tachycardia After Cardiac Resynchronization Therapy
- Author
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Cori, Andrea, Bongiorni, Maria, Arena, Giuseppe, Soldati, Ezio, Giannola, Gabriele, Zucchelli, Giulio, and Balbarini, Alberto
- Abstract
Abstract??It is well established that coronary artery disease with healed myocardial infarction is the most common backdrop for ventricular tachycardia (VT). Although the clinical benefits of biventricular pacing (BivP) in the treatment of severe heart failure are well documented, exact relation with ventricular arrhythmias remains still unclear.We describe a case of a patient, whitout a previous history of arrhythmic episodes, in which the onset of several episodes of VT presented immediatly after cardiac resynchronization therapy (CRT) and did not occur after BivP discontinuation.
- Published
- 2005
- Full Text
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27. Movie mecca.
- Author
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Bongiorni, Sara
- Subjects
ECONOMIC development ,MOTION picture industry ,TAX credits ,TAX incentives ,TAXATION ,PUBLIC finance - Abstract
Focuses on the impact of Louisiana's movie industry on the state's economy. Employment offered to the locals; Approval of 83 million dollars in tax credits; Improvement of cost for smaller productions.
- Published
- 2005
28. NEW BLOOD.
- Author
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Bongiorni, Sara, Clark, Steve, Guarisco, Tom, and Cohen, Hal
- Subjects
PUBLIC officers ,PUBLIC administration - Abstract
Introduces some of the officers of Baton Rouge, Louisiana under the administration of Mayor Melvin Holden. Stephen Moret, chief of the Chamber of Greater Baton Rouge; East Baton Rouge superintendent Charlotte Placide; Louisiana State University chancellor Sean O'Keefe; Mark Thornton, head of Baton Rouge's parks system; Public transportation head Dwight Brashear.
- Published
- 2005
29. The CHAMBER'S next MOVE.
- Author
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Bongiorni, Sara
- Subjects
BOARDS of trade ,COMMERCIAL associations ,ASSOCIATIONS, institutions, etc. ,REGIONALISM ,ECONOMIC development - Abstract
Discusses the plan of the Chamber of Greater Baton Rouge to reinvent itself as a regional force for job creation. Work with local chambers in other parishes to compete for new business; Withdrawal of Bank One from the chamber; Frustration within the chamber's ranks over the economy; Chamber's exploration of becoming regional; Business enterprises' call for dynamic leadership in economic development and in jobs. INSETS: RUMBLE!;BACK IN THE RACES..
- Published
- 2004
30. The Great Divide.
- Author
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Bongiorni, Sara
- Subjects
BUSINESSMEN ,VENTURE capital ,ANGEL investors - Abstract
Reports in the importance for entrepreneurs in Baton Rouge, Louisiana to close the gap between start-up money and serious capital. Lack of available seed capital; Role of angel investors in funding the "baby steps" of fledgling entrepreneurs.
- Published
- 2004
31. No pipe dream.
- Author
-
Bongiorni, Sara
- Subjects
EXECUTIVES ,CUSTOMER services - Abstract
Profiles Tim Barfield, the president of The Shaw Group Inc. in Baton Rouge, Louisiana. Career history of Barfield; Provision of industrial services and nuclear power plant construction; Accomplishments of Barfield in the company.
- Published
- 2004
32. FUMBLE!
- Author
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Bongiorni, Sara
- Subjects
INVESTMENT of public funds ,TELEVISED sports ,INVESTMENTS ,TELEVISION broadcasting - Abstract
Discusses the risky investment of the state of Louisiana in The Football Network (TFN). Failure of state executives to practice standard elements of due diligence in investment; Failure of the state to request for an independent outsider to analyze the logic of the business plan of TFN; Terms of the investment deal. INSET: HERE'S THE DEAL..
- Published
- 2004
33. Imprinted Facultative Heterochromatization in Mealybugs
- Author
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Bongiorni, Silvia and Prantera, Giorgio
- Abstract
In lecanoid Coccids, or mealybugs, the male development is accompanied by the facultative heterochromatization of the entire, paternally derived, haploid chromosome set. This epigenetic phenomenon occurs in all the cells of mid-cleavage male embryos. Consequently, the Coccid chromosome system offers a powerful tool for gaining insights into the structure of facultative heterochromatin, and into the epigenetic mechanisms of its imprinted, developmentally regulated formation. This paper will present new data and summarize recent studies on genomic imprinting and facultative heterochromatization in mealybugs. First, the existence and the possible role of DNA methylation as an epigenetic modification that fulfills the requisites of the imprinting process in mealybugs will be considered. The second part of this paper will focus on proteins involved in the facultative heterochromatization process. In particular, the involvement of an HP-1-like protein in the silencing of the paternally derived haploid chromosome set and its interaction with the lysine 9 methylated isoform of histone H3 will be discussed.
- Published
- 2003
- Full Text
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34. Facultative heterochromatization in parahaploid male mealybugs: involvement of a heterochromatin-associated protein.
- Author
-
Bongiorni, S, Mazzuoli, M, Masci, S, and Prantera, G
- Abstract
The behavior of chromosomes during development of the mealybug Planococcus citri provides one of the most dramatic examples of facultative heterochromatization. In male embryos, the entire haploid paternal chromosome set becomes heterochromatic at mid-cleavage. Male mealybugs are thus functionally haploid, owing to heterochromatization (parahaploidy). To understand the mechanisms underlying facultative heterochromatization in male mealybugs, we have investigated the possible involvement of an HP-1-like protein in this process. HP-1 is a conserved, nonhistone chromosomal protein with a proposed role in heterochromatinization in other species. It was first identified in Drosophila melanogaster as a protein enriched in the constitutive heterochromatin of polytene chromosome. Using a monoclonal antibody raised against the Drosophila HP-1 in immunoblot and immunocytological experiments, we provide evidence for the presence of an HP-1-like in Planococcus citri males and females. In males, the HP-1-like protein is preferentially associated with the male-specific heterochromatin. In the developing male embryos, its appearance precedes the onset of heterochromatization. In females, the HP-1-like protein displays a scattered but reproducible localization pattern along chromosomes. The results indicate a role for an HP-1-like protein in the facultative heterochromatization process.
- Published
- 2001
35. Facultative heterochromatization in parahaploid male mealybugs: involvement of a heterochromatin-associated protein
- Author
-
Bongiorni, Silvia, Mazzuoli, Milena, Masci, Stefania, and Prantera, Giorgio
- Abstract
The behavior of chromosomes during development of the mealybug Planococcus citri provides one of the most dramatic examples of facultative heterochromatization. In male embryos, the entire haploid paternal chromosome set becomes heterochromatic at mid-cleavage. Male mealybugs are thus functionally haploid, owing to heterochromatization (parahaploidy). To understand the mechanisms underlying facultative heterochromatization in male mealybugs, we have investigated the possible involvement of an HP-1-like protein in this process. HP-1 is a conserved, nonhistone chromosomal protein with a proposed role in heterochromatinization in other species. It was first identified in Drosophila melanogaster as a protein enriched in the constitutive heterochromatin of polytene chromosome. Using a monoclonal antibody raised against the Drosophila HP-1 in immunoblot and immunocytological experiments, we provide evidence for the presence of an HP-1-like in Planococcus citri males and females. In males, the HP-1-like protein is preferentially associated with the male-specific heterochromatin. In the developing male embryos, its appearance precedes the onset of heterochromatization. In females, the HP-1-like protein displays a scattered but reproducible localization pattern along chromosomes. The results indicate a role for an HP-1-like protein in the facultative heterochromatization process.
- Published
- 2001
- Full Text
- View/download PDF
36. The Best + ICD Trial
- Author
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Cappato, R., Bongiorni, M.G., Brignole, M., Capucci, A., Gaita, F., Mangiameli, S., Montenero, A., Pedretti, R., Raviele, A., Salerno, J., and Sermasi, S.
- Abstract
ta-blocker STrategy plus Implantable Cardioverter Defibrillator (BEST + ICD) Trial is a multicenter prospective randomized study in which the hypothesis will be tested of whether, in high-risk post-myocardial infarction (MI) patients already treated with β-blockers, therapy guided by electrophysiologic study (EPS) will improve survival, compared to conventional therapy. Eligible patients for the study are survivors of a recent MI (>5 and <21 days), aged <80 years, who have left ventricular ejection fraction ≤35 % and one or more of the following additional risk factors: ventricular premature beats ≥10/h, reduced heart rate variability (SDNN <70 ms), and presence of ventricular late potentials. These patients represent about 9 % of all patients with recent MI and are expected to have a 2-year all-cause mortality ≥25 %, sudden in 50 % of cases. The main exclusion criteria from the study are a history of sustained ventricular arrhythmias, documentation of non-sustained ventricular tachycardia during the screening phase, need for myocardial revascularization, and contraindications or intolerance to β-blocker therapy. Eligible patients will be randomized with a 2:3 ratio to two different therapeutic strategies: conventional strategy or EPS/ICD strategy. Patients allocated to conventional strategy will be treated, whenever possible, with aspirin, ACE inhibitor, and statine. In addition to the conventional therapy, patients allocated to EPS/ICD strategy will undergo an EPS: inducible patients (35 %) will receive a prophylactic ICD, whereas noninducible patients will be only conventionally treated. The primary endpoint of the study is death from all-causes. The duration of recruitment will be 2 years and that of follow-up will be variable, since all patients will be followed to a common termination date. By hypothesizing a 30 % reduction in the 2-year morality (from 20 % to 14 %) in the EPS/ICD group compared to conventionally treated patients, 1200 patients need to be randomized, of whom 480 to conventional strategy and 720 to EPS/ICD strategy. A triangular, 2-sided sequential design with preset boundaries (p <0.05) will be used to permit early termination of the trial if efficacy, no difference or inefficacy will be found. Data analysis will be done on the basis of both intention-to-treat (primary analysis) and on treatment analysis (secondary analysis). Randomisiert werden sollen Patienten 5–21 Tage nach Myokardinfarkt. Diese Patienten sollen jünger sein als 80 Jahre, eine linksventrikuläre Auswurffraktion von maximal 35 % aufweisen und eine Metoprolol-Therapie von mindestens 25 mg täglich tolerieren. Darüber hinaus sollen einer oder mehrere der folgenden Risikofaktoren vorliegen: ≥ 10 ventrikuläre Extrasystolen pro Stunde, reduzierte Variabilität der Herfrequenz (SDNN < 70 ms), Nachweis von Spätpotential des Ventrikels. Etwa 9 % aller Patienten mit kurz zurückliegendem Myokardinfarkt erfüllen diese Kriterien. Für diese Patienten erwartet man innerhalb der ersten 2 Jahre nach Infarkt eine Mortalität von ≥ 25%; von diesen Todesfällen treten 50% plötzlich ein . Geeignete Patienten werden im Verhältnis 2:3 randomisiert und einer herkömmlichen oder einer EPU-bestimmten Therapie zugeführt. Patienten der EPU-bestimmten Therapie erhalten eine elektrophysiologische Untersuchung. Hier erwartet man einen Anteil von 35 % mit induzierbarer ventrikulärer Tachykardie oder Kammerflimmern. Diesen Patienten wird prophylaktisch ein kardioverter Defibrillator implantiert. Die übrigen Patienten der Gruppe, bei denen solche Arrhythmien nicht induzierbar sind, werden einer herkömmlichen Therapie zugeführt. Primärer Endpunkt der Studie ist die Gesamtmortalität. Unter der Hypothese, daß die übliche Sterblichkeitsrate in der EPU-Gruppe innerhalb der ersten beiden Jahre von 20 % auf 14 %, also um 30 % reduziert werden kann, müssen 1200 Patienten randomisiert werden (480 Patienten unter herkömmlicher und 720 Patienten unter EPU-bestimmter Therapie). Ein trianguläres, 2-seitiges, sequenzielles Design mit vorab festgesetzten Grenzen (p <0,05) soll sicherstellen, daß die Studie vorzeitig abgebrochen werden kann, wenn eine Wirksamkeit, kein Unterschied zwischen den Behandlungen oder mangelnde Wirksamkeit nachgewiesen werden. Die Analyse der Daten wird sowohl auf der Basis der Intention-to-Treat (primäre Analyse) als auch anhand der in Behandlung befindlichen Patienten (Sekundärauswertung) erfolgen.
- Published
- 1999
- Full Text
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37. TOTAL REVENUE JUMPS 11 PERCENT IN 1998.
- Author
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Bongiorni, Sara
- Subjects
PETROLEUM chemicals industry ,PRIVATE companies ,ECONOMIC history - Abstract
Focuses on the economic growth in Baton Rouge, Louisiana in 1998. Performance of the city's 100 largest private companies; Influence of the petrochemical industry on the state's economic growth; Growth of the state's construction industry.
- Published
- 1999
38. `Another jewel along North Boulevard'.
- Author
-
Bongiorni, Sara
- Subjects
PUBLIC building maintenance & repair ,LOUISIANA governors - Abstract
Discusses the state-funded renovation work on the Old State Capitol mansion at North Boulevard in Baton Rouge, Louisiana. State governors who once lived in there; Project specifications; Renovation costs.
- Published
- 1999
39. Bringing Louisiana's history to light.
- Author
-
Bongiorni, Sara
- Subjects
MUSEUMS - Abstract
Features the Louisiana State University Rural Life Museum in Baton Rouge. International recognitions received by the museum; Role of the museum in the city's ability to attract visitors; Historical background of the museum founded by Steele Burden; Focus of the collection on authentic historic buildings. INSET: The Rural Life Museum..
- Published
- 1999
40. The voice of LPB.
- Author
-
Bongiorni, Sara
- Subjects
TELEVISION stations ,WOMEN in television broadcasting - Abstract
Profiles Beth Courney, president and chief executive officer of Louisiana Public Broadcasting (LPB). Educational background; Highlights of Courney's career in broadcasting; Major influences; Involvement in several local civic organizations; Accomplishments at LPB; Experience of asking viewers for financial support during LPB's three-times-a-year pledge drives.
- Published
- 1999
41. Not your typical banker.
- Author
-
Bongiorni, Sara
- Subjects
BANKERS - Abstract
Profiles Kyle Waters, regional president for Hibernia National Bank in Baton Rouge, Louisiana. Education; Management style; Family; Hobbies; Visibility as a banker in Baton Rouge; Attitude towards work; Changes noted in the banking industry in the region; Efforts to bring change in the city. INSET: Bankers on Waters..
- Published
- 1999
42. Hope for the future.
- Author
-
Bongiorni, Sara
- Subjects
RETAIL stores ,FAMILY-owned business enterprises - Abstract
Reports how Romano's Pack and Save Inc., a family business on the brink of financial collapse, recovered through the help of Hibernia Bank and the Louisiana State University business school. Condition of the store; History of Romano's store; Losses suffered; How the students managed to save the store.
- Published
- 1998
43. Early Management of Elderly Dysvascular Below-Knee Amputees
- Author
-
Cutson, Toni M., Bongiorni, Dennis, Michael, John W., and Kochersberger, Gary
- Abstract
The majority of transtibial (belowknee) amputations occur in elderly patients with systemic vascular disease. Rehabilitation efforts toward prosthetic ambulation are frequently delayed awaiting postoperative healing of the vascular compromised limb. Rehabilitation becomes more difficult, more costly and less successful the longer it is delayed after surgery, especially among elderly amputees. Early ambulation reduces the risk of complications such as thromboembolism, pneumonia and deconditioning in the older patient as well as enhances remaining life. An early coordinated post-amputation rehabilitation program reduces the time to prosthetic ambulation and the risk of further debility and failure among elderly amputees. The rigid removable dressing was incorporated into the program and found to be a safe method of residual limb shrinkage among elderly dysvascular transtibial amputees.
- Published
- 1994
44. Early Management of Elderly Dysvascular BelowKnee Amputees
- Author
-
Cutson, Toni M., Bongiorni, Dennis, Michael, John W., and Kochersberger, Gary
- Abstract
The majority of transtibial (below-knee) amputations occur in elderly patients with systemic vascular disease. Rehabilitation efforts toward prosthetic ambulation are frequently delayed awaiting postoperative healing of the vascular compromised limb. Rehabilitation becomes more difficult, more costly and less successful the longer it is delayed after surgery, especially among elderly amputees. Early ambulation reduces the risk of complications such as thromboembolism, pneumonia and deconditioning in the older patient as well as enhances remaining life. An early coordinated post-amputation rehabilitation program reduces the time to prosthetic ambulation and the risk of further debility and failure among elderly amputees. The rigid removable dressing was incorporated into the program and found to be a safe method of residual limb shrinkage among elderly dysvascular transtibial amputees.
- Published
- 1994
45. Adverse Clinical Events in Dependent Long‐Term Nursing Home Residents
- Author
-
Bernardini, Bruno, Meinecke, Claudia, Zaccarini, Cinzia, Bongiorni, Nadia, Fabbrini, Stefano, Gilardi, Camilla, Bonaccorso, Orazio, and Guaita, Antonio
- Published
- 1993
- Full Text
- View/download PDF
46. Cytogenetic characterization of the genome of mealybug Planococcus citri(Homoptera, Coccoidea)
- Author
-
Ferraro, Marina, Epifani, Chiara, Bongiorni, Silvia, Nardone, AnnaMaria, Parodi-Delfino, Saviana, and Prantera, Giorgio
- Abstract
SummaryMealybugs although being agriculturally harmful insects have been very poorly studied by modern cytogenetics techniques, and no cytotaxonomic criteria to distinguish between closely related species is available yet. In the mealybug Planococcus citri(2n=10) male and female individuals are both diploid, however in males, at the stage of blastula, the haploid chromosome set of paternal origin becomes heterochromatic, even though its complete inertia has been considered questionable. Here we present data on the cytogenetic characterization of the chromosomes of Planococcus citri. We report on (i) the fluorescence karyotype (D287/170), which to our knowledge is the first banded karyotype of a mealybug to be described; (ii) the chromosome localization of constitutive heterochromatin; (iii) the chromosome localization of rDNA sites; (iv) NORs activity. Our data also show, for the first time, that in the heterochromatic chromosome set ribosomal genes are still active.
- Published
- 1998
- Full Text
- View/download PDF
47. A Selection of Poems by Ferruccio Brugnaro
- Author
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Bongiorni, Kevin and Grimm, Reinhold
- Published
- 1998
- Full Text
- View/download PDF
48. Response of Mammalian Cells Irradiated with 30 MV X-rays in the Presence of a Uniform 20-kilogauss Magnetic Field
- Author
-
Nath, Ravinder, Schulz, R. J., and Bongiorni, P.
- Abstract
The effects of intense magnetic fields on the survival curves for aerated and hypoxic Chinese hamster lung cells exposed to 30 MV X-rays were investigated. A uniform 20-kilogauss magnetic field, as well as a non-uniform magnetic field with an average value of 17·5 kilogauss and a gradient of 2·3 kilogauss/cm, were employed. A study of the repair of sublethal damage for cells exposed to the magnetic field only during the split-dose irradiations, and the effect of exposure to the magnetic field alone for 2 hours, were also studied. For each of these four experiments, no effects attributable to the magnetic field were detected.
- Published
- 1980
- Full Text
- View/download PDF
49. Does Radiographic Osteoarthritis Correlate with Flexibility of the Lumbar Spine?
- Author
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Weiner, Debra K., Distell, Bruce, Studenski, Stephanie, Martinez, Salutario, Lomasney, Laurie, and Bongiorni, Dennis
- Published
- 1994
- Full Text
- View/download PDF
50. Increased prevalence of ventricular arrhythmias in essential hypertensives with dipyridamole-induced ischemic-like S-T segment changes
- Author
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Lucarin, Alessandra R, Picano, Eugenio, Bongiorni, Maria Grazia, Lattanzi, Fabio, Marini, Cecilia, Paperini, Luca, L'Abbate, Antonio, and Salvett, Antonio
- Abstract
Essential hypertensives are at greater risk for ventricular arrhythmias than normotensive controls. A reduction in coronary flow reserve may be one of the mechanisms underlying this increased prevalence of ventricular dysrhythmias in hypertensives. It has previously been shown that dipyridamole infusion may provoke ischemic-like S-T segment depression in essential hypertensives with angiographically normal coronary arteries and reduced flow reserve. The aim of the present study was to assess whether electrocardiographic positivity (S-T segment depression ≥0.1 mV from baseline) during dipyridamole testing (12-lead electrocardiogram and two-dimensional echomonitoring, with the infusion of 0.84mgkg dipyridamole over 10min) might identify hypertensives at greater risk for ventricular dysrhythmias. We therefore studied 51 mild-to-moderate essential hypertensives by dipyridamole testing and 48-h Holter monitoring. All patients were off therapy for at least 2 weeks before testing and Holter evaluation. Left ventricular mass (by Penn convention) and ejection fraction (by Teichholtz rule) were evaluated by two-dimensional echocardiography. Lown classes O-l were found in 31 patients (Group 1) and Lown classes II—IV in 20 (Group 2). The two groups overlapped for mean blood pressure (121 ± 9 versus 124 ± 8mmHg), left ventricular mass index (120 ± 27 versus 141 ± 42gm2) and left ventricular ejection fraction (54 ± 6 versus 52 ± 6). An electrocardiographically-positive dipyridamole test was found in seven of Group I and 16 of Group II patients (23 versus 80 P< 0.01). No patient showed a transient, either regional or global, systolic dysfunction during dipyridamole testing. We conclude that dipyridamole-induced electrocardiographic changes can be helpful in identifying essential hypertensives at higher risk for significant ventricular arrhythmias, pointing to the reduction in coronary flow reserve as an important pathogenetic pathway of arrhythmias in these patients.
- Published
- 1991
Catalog
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