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Your search keyword '"Barrenäs, Fredrik"' showing total 3 results
Start Over Author "Barrenäs, Fredrik" Publication Type Magazines
3 results on '"Barrenäs, Fredrik"'

1. MicroRNAs act complementarily to regulate disease-related mRNA modules in human diseases

Author

Chavali, Sreenivas, Bruhn, Sören, Tiemann, Katrin, Sætrom, Pål, Barrenäs, Fredrik, Saito, Takaya, Kanduri, Kartiek, Wang, Hui, and Benson, Mikael

Abstract

The authors set out to determine the mode of action of different miRNAs in complex diseases. The main conclusion of this article is that miRNAs act primarily in a complementary rather than synergistic manner to regulate functionally related, disease-relevant mRNAs.

Published
2013
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2. A Generally Applicable Translational Strategy Identifies S100A4 as a Candidate Gene in Allergy

Author

Bruhn, Sören, Fang, Yu, Barrenäs, Fredrik, Gustafsson, Mika, Zhang, Huan, Konstantinell, Aelita, Krönke, Andrea, Sönnichsen, Birte, Bresnick, Anne, Dulyaninova, Natalya, Wang, Hui, Zhao, Yelin, Klingelhöfer, Jörg, Ambartsumian, Noona, Beck, Mette K., Nestor, Colm, Bona, Elsa, Xiang, Zou, and Benson, Mikael

Abstract

A module-based strategy identified and validated an important diagnostic and therapeutic candidate gene in allergy.

Published
2014
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3. Highly interconnected genes in disease-specific networks are enriched for disease-associated polymorphisms

Author

Barrenäs, Fredrik, Chavali, Sreenivas, Alves, Alexessander, Coin, Lachlan, Jarvelin, Marjo-Riitta, Jörnsten, Rebecka, Langston, Michael, Ramasamy, Adaikalavan, Rogers, Gary, Wang, Hui, and Benson, Mikael

Abstract

Complex diseases are associated with altered interactions between thousands of genes. We developed a novel method to identify and prioritize disease genes, which was generally applicable to complex diseases.

Published
2012
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