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Iodometric and spectrophotometric methods were developed for the analysis of the new antibiotic cephradine. The procedures are modifications of known methods but are novel in employing a specific β-lactamase for hydrolysis of the β-lactam ring of the cephalosporin molecule. The iodometric method is rapid, precise, and accurate, but it requires fairly large amounts of cephradine. The spectrophotometric method, using differential UV absorption at 260 nm, is more rapid and more sensitive than the iodometric method but somewhat less accurate. Both methods proved useful for the routine assay of cephradine in certain formulations.

Several letters to the editor are presented in on several pets including one on having egrets as pets, another with deer as pets, and one on reading the periodical "Harper's Young People."

Several letters to the editor are presented in response to articles in previous issues including Puss Hunter's recipe, another recipe for water cookies, and feeding minnows.