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Your search keyword '"ACTIN"' showing total 833 results
Start Over Descriptor "ACTIN" Publication Type Magazines
833 results on '"ACTIN"'

4. Data from Indian Institute of Science Broaden Understanding of Alzheimer Disease (Mitigation of synaptic and memory impairments via F-actin stabilization in Alzheimer's disease)

Subjects
Disability, Medical research, Medicine, Experimental, Diseases, Muscle proteins, Actin, Alzheimer's disease, Physical fitness, Health
Abstract

2024 SEP 28 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Researchers detail new data in Alzheimer disease. According to news reporting from [...]

Published
2024

9. EGFR does not directly interact with cortical actin: A SRRF'n'TIRF Study

Subjects
Muscle proteins, Actin, Physical fitness, Epidermal growth factor
Abstract

2024 AUG 10 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- According to news reporting based on a preprint abstract, our journalists obtained […]

Published
2024

12. Disruption of P2Y2 signaling promotes breast tumor cell dissemination by reducing ATP-dependent calcium elevation and actin localization to cell junctions (Updated June 13, 2024)

Subjects
Women -- Health aspects, Metastasis, Adenosine triphosphate, Muscle proteins, Actin, Breast cancer, Health, Women's issues/gender studies
Abstract

2024 JUL 4 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- According to news reporting based on a preprint abstract, our journalists obtained the following [...]

Published
2024

16. Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies (Updated March 6, 2024)

Subjects
Genetic research, Genes, Nervous system diseases -- Risk factors, Muscle proteins, Actin, Physical fitness, Health
Abstract

2024 MAR 23 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- According to news reporting based on a preprint abstract, our journalists obtained [...]

Published
2024

17. New Colon Cancer Data Have Been Reported by Researchers at Fudan University (Artificial Water Channel Promoting Depolymerization of Actin Filaments To Trigger Cancer Cell Apoptosis)

Subjects
Oncology, Experimental, Colon cancer, Muscle proteins, Actin, Apoptosis, Cancer -- Research, Physical fitness, Health, Fudan University
Abstract

2024 MAR 23 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on Oncology - Colon Cancer have been published. According [...]

Published
2024

21. Researchers' Work from First Affiliated Hospital of Xinjiang Medical University Focuses on Non-Small Cell Lung Cancer (Fascin actin-bundling protein 1 regulates non-small cell lung cancer progression by influencing the transcription and ...)

Subjects
Protein binding, Lung cancer, Small cell -- Development and progression -- Prevention -- Prognosis, Muscle proteins, Actin, RNA, Lung cancer, Non-small cell -- Development and progression -- Prognosis -- Prevention, Genetic transcription, Physical fitness, Health
Abstract

2023 DEC 30 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Data detailed on non-small cell lung cancer have been presented. According to [...]

Published
2023

23. Repeated FRAP of the actin-binding protein CapG in the cell nucleus - a functional assay for EGF signaling in the single live breast cancer cell

Subjects
Women -- Health aspects, Binding proteins, Protein binding, Muscle proteins, Actin, Breast cancer, Epidermal growth factor, Health, Women's issues/gender studies
Abstract

2023 OCT 19 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- According to news reporting based on a preprint abstract, our journalists obtained the following [...]

Published
2023

26. Anisotropic stretch biases the self-organization of actin fibers in multicellular Hydra aggregates.

Subjects
TISSUE mechanics, DEVELOPMENTAL biology, HYDRA (Marine life), ACTIN, CELL morphology
Abstract

According to a preprint abstract, researchers studied the self-organization of actin fibers in multicellular Hydra aggregates to understand how mechanics contribute to pattern formation. They used the regenerative abilities of Hydra vulgaris to observe the development of actin patterns over time. The researchers found that stretch can strongly bias the orientation of the actin meshwork, even without the presence of a Wnt gradient. This study provides insights into the role of tissue mechanics in the alignment of actin fibers during development. Please note that this preprint has not been peer-reviewed. [Extracted from the article]

Published
2024

27. Integrated structural model of the palladin-actin complex using XL-MS, docking, NMR, and SAXS.

Subjects
TANDEM mass spectrometry, SMALL-angle scattering, CARRIER proteins, F-actin, ACTIN
Abstract

This article discusses a study on the interaction between palladin, an actin binding protein, and F-actin, which is involved in the metastasis of certain types of cancer. The researchers used various techniques such as chemical crosslinking, mass spectrometry, docking, small angle X-ray scattering, and NMR spectroscopy to determine the binding conformation and structural model of the palladin-actin complex. The study revealed that palladin interacts with and stabilizes F-actin at the interface between two actin monomers. This research provides valuable insights into the role of palladin in promoting cancer metastasis through the regulation of actin dynamics. [Extracted from the article]

Published
2024

28. Okayama University Researcher Adds New Study Findings to Research in Muscle Proteins (Direct Binding of Synaptopodin 2-Like Protein to Alpha-Actinin Contributes to Actin Bundle Formation in Cardiomyocytes).

Subjects
MUSCLE proteins, ACTIN, RESEARCH personnel, PROTEINS, MICROFILAMENT proteins
Abstract

The article explores how Synaptopodin 2-like protein (SYNPO2L) interacts with alpha-actinin to aid in actin bundle formation in cardiomyocytes. Topics include SYNPO2L's role in binding to alpha-actinin and actin filaments, the effect of SYNPO2L on actin bundling, and the implications for sarcomere formation and maintenance.

Published
2024

33. Ca2+/Calmodulin Dependent Protein Kinase Kinase-2 (CaMKK2) promotes Protein Kinase G (PKG)-dependent actin cytoskeletal assembly to increase tumor metastasis

Subjects
Women -- Health aspects, Metastasis -- Care and treatment, Actin, Protein kinases, Calmodulin, Health, Women's issues/gender studies
Abstract

2023 MAY 4 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- According to news reporting based on a preprint abstract, our journalists obtained the following [...]

Published
2023

46. Global coordination of protrusive forces in migrating immune cells.

Subjects
CYTOLOGY, CELL nuclei, F-actin, ACTIN, LEUCOCYTES
Abstract

According to a preprint abstract, leukocytes, or immune cells, rely on their ability to navigate through complex tissues to mount efficient immune responses. In dense environments, leukocytes change their configuration and position their nucleus behind their centrosome and organelles. This allows for the assembly of a central F-actin pool, which pushes outward to create a temporary path for the organelles and nucleus. However, this shift in configuration can impair migration in restrictive environments. This research establishes an actin regulatory loop that balances path dilation with the advancement of the leading edge of the cell to maintain cellular coherence. Please note that this preprint has not been peer-reviewed. [Extracted from the article]

Published
2024

47. The longitudinal growth of the embryo of the kelp Saccharina depends on actin filaments that control the formation of an alginate corset in the cell wall.

Subjects
ALGINIC acid, EMBRYOS, SACCHARINA, ACTIN, MORPHOLOGY
Abstract

According to a preprint abstract, researchers have found that the growth of the kelp Saccharina's embryo is dependent on actin filaments that control the formation of an alginate corset in the cell wall. The researchers discovered that the anisotropy in cell shape during embryogenesis is accompanied by a spatio-temporal pattern of accumulation of alginates in the cell wall. They also found that the presence of cortical actin filaments affects the pattern of alginate composition in the walls of the embryo. This research provides insights into the growth and development of Saccharina embryos. [Extracted from the article]

Published
2024

48. Research on Immunology Described by Researchers at Aster CMI Hospital (Immune dysregulation due to bi-allelic mutation of the actin remodeling protein DIAPH1).

Subjects
RESEARCH personnel, IMMUNOLOGY, ACTIN, INFLAMMATORY bowel diseases
Abstract

Researchers at Aster CMI Hospital in Bengaluru, India have identified a new genetic finding in a child with severe inflammatory bowel disease. The child had a bi-allelic mutation of the actin remodeling protein DIAPH1, which is associated with complex neurological and developmental phenotypes. This case expands the clinical spectrum of DIAPH1 deficiency and suggests that autoimmune or inflammatory enteropathy may be the most prominent immunological manifestation of the disease. The study highlights the challenges in diagnosing and treating severe inflammatory diseases in children and emphasizes the importance of genetic research in understanding the underlying causes of these conditions. [Extracted from the article]

Published
2024

49. The CCT chaperonin and actin modulate the ER and RNA-binding protein condensation during oogenesis to maintain translational repression of maternal mRNA and oocyte quality.

Subjects
RNA-binding proteins, CARRIER proteins, OOGENESIS, OVUM, ACTIN
Abstract

A preprint abstract from biorxiv.org discusses the regulation of maternal mRNAs during oogenesis and its importance for proper gamete production and prevention of birth defects and infertility. The study focuses on the KH-domain MEX-3 protein and its gel-like properties, as well as the role of the CCT chaperonin and actin in preventing ectopic condensation of RNA-binding proteins in maturing oocytes. This regulatory network is crucial for maintaining oocyte quality and preventing infertility, and may have implications for understanding the role of hMex3 phase transitions in cancer. The preprint has not yet undergone peer review. [Extracted from the article]

Published
2024

50. C-terminal CDC42 variants in autoinflammatory patients specifically trigger actin defects and NF-kB hyperactivation.

Subjects
CELL cycle proteins, NF-kappa B, ACTIN, RHO GTPases, CYTOSKELETON
Abstract

A recent preprint abstract discusses the findings of a study on CDC42 variants in autoinflammatory patients. The study aimed to investigate whether four CDC42 variants, specifically those located in the C-terminal region, share common signaling alterations. The results showed that the C-terminal variants exhibited aberrant subcellular localizations and functional alterations, including a reduction in actin filament polymerization and increased NF-kB nuclear translocation and phosphorylation. However, there was no causal relationship found between these two events. The study suggests that CDC42 patients should not necessarily be classified among actinopathies and highlights the potential for more personalized therapeutic interventions based on the functional defects observed. [Extracted from the article]

Published
2024

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