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2. PrPCcontrols epithelial-to-mesenchymal transition in EGFR-mutated NSCLC: implications for TKI resistance and patient follow-up
- Author
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Lailler, Claire, Didelot, Audrey, Garinet, Simon, Berthou, Hugo, Sroussi, Marine, de Reyniès, Aurélien, Dedhar, Shoukat, Martin-Lannerée, Séverine, Fabre, Elizabeth, Le Pimpec-Barthes, Françoise, Perrier, Alexandre, Poindessous, Virginie, Mansuet-Lupo, Audrey, Djouadi, Fatima, Launay, Jean-Marie, Laurent-Puig, Pierre, Blons, Hélène, and Mouillet-Richard, Sophie
- Abstract
Patients with EGFR-mutated non-small cell lung cancer (NSCLC) benefit from treatment with tyrosine kinase inhibitors (TKI) targeting EGFR. Despite improvements in patient care, especially with the 3rd generation TKI osimertinib, disease relapse is observed in all patients. Among the various processes involved in TKI resistance, epithelial-to-mesenchymal transition (EMT) is far from being fully characterized. We hypothesized that the cellular prion protein PrPCcould be involved in EMT and EGFR-TKI resistance in NSCLC. Using 5 independent lung adenocarcinoma datasets, including our own cohort, we document that the expression of the PRNPgene encoding PrPCis associated with EMT. By manipulating the levels of PrPCin different EGFR-mutated NSCLC cell lines, we firmly establish that the expression of PrPCis mandatory for cells to maintain or acquire a mesenchymal phenotype. Mechanistically, we show that PrPCoperates through an ILK-RBPJ cascade, which also controls the expression of EGFR. Our data further demonstrate that PrPClevels are elevated in EGFR-mutated versus wild-type tumours or upon EGFR activation in vitro. In addition, we provide evidence that PRNPlevels increase with TKI resistance and that reducing PRNPexpression sensitizes cells to osimertinib. Finally, we found that plasma PrPClevels are increased in EGFR-mutated NSCLC patients from 2 independent cohorts and that their longitudinal evolution mirrors that of disease. Altogether, these findings define PrPCas a candidate driver of EMT-dependent resistance to EGFR-TKI in NSCLC. They further suggest that monitoring plasma PrPClevels may represent a valuable non-invasive strategy for patient follow-up and warrant considering PrPC-targeted therapies for EGFR-mutated NSCLC patients with TKI failure.
- Published
- 2024
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3. A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts
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Bravo, Laura, Simões, Joana FF, Cardoso, Victor R, Adisa, Adewale, Aguilera, Maria L, Arnaud, Alexis, Biccard, Bruce, Calvache, Jose, Chernbumroong, Saisakul, Elhadi, Muhammed, Ghosh, Dhruv, Gujjuri, Rohan, Harrison, Ewen, Ho, Michael WS, Kasivisvanathan, Veerappan, Kouli, Omar, Lederhuber, Hans, Li, Elizabeth, Löffler, Markus W, Isik, Arda, Marcus, Hani, Martin, Janet, McLean, Kenneth A, Minaya-Bravo, Ana, Modolo, María Marta, Nepogodiev, Dmitri, Pellino, Gianluca, Picciochi, Maria, Pockney, Peter, van Ramshorst, Gabriëlle, Riad, Aya, Sayyed, Raza, Sund, Malin, Gkoutos, Georgios, Bhangu, Aneel A, Glasbey, James C, Bravo, L, Cardoso, V, Glasbey, J, Chernbumroong, S, Nepogodiev, D, Simoes, JFF, Mclean, KA, Bhangu, AA, Gkoutos, G, Kadir, B, Omar, O, Revell, E, Bahrami-Hessari, M, Ahmed, Waheed-Ul-Rahman, Argus, Leah, Ball, Alasdair, Bhangu, Aneel, Bywater, Edward P, Blanco-Colino, Ruth, Brar, Amanpreet, Chaudhry, Daoud, Dawson, Brett E, Duran, Irani, Elhadi, Muhammed, Glasbey, James C, Gujjuri, Rohan R, Jones, Conor S, Harrison, Ewen M, Kamarajah, Sivesh K, Keatley, James M, Lawday, Samuel, Li, Elizabeth, Mann, Harvinder, Marson, Ella J, Mclean, Kenneth A, Nepogodiev, Dmitri, Norman, Lisa, Ots, Riinu, Outani, Oumaima, Picciochi, Maria, Santos, Irène, Shaw, Catherine, Taylor, Elliott H, Trout, Isobel M, Varghese, Chris, Venn, Mary L, Xu, William, Dajti, Irida, Gjata, Arben, Kacimi, Salah Eddine Oussama, Boccalatte, Luis, Modolo, Maria Marta, Cox, Daniel, Pockney, Peter, Aigner, Felix, Kronberger, Irmgard Elisabeth, Samadov, Elgun, Alderazi, Amer, Padmore, Greg, van Ramshorst, Gabrielle, Lawani, Ismaïl, Cerovac, Anis, Delibegovic, Samir, Baiocchi, Glauco, Gomes, Gustavo Mendonça Ataíde, Lima Buarque, Igor, Gohar, Muhammad, Slavchev, Mihail, Nwegbu, Chukwuemeka, Agarwal, Arnav, Brar, Amanpreet, Martin, Janet, Ng-Kamstra, Joshua, Olivos, Maricarmen, Lou, Wenhui, Ren, Dong-Lin, Calvache, Jose Andres, Perez Rivera, Carlos J-, Danic Hadzibegovic, Ana, Kopjar, Tomislav, 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Aiste, Rasoaherinomenjanahary, Fanjandrainy, Samison, Luc Hervé, Roslani, April Camilla, Durán Sánchez, Iran Irani, Gonzalez, Diana Samantha, Martinez, Laura, Martínez, María José, Nayen, Alejandra, Ramos-De la Medina, Antonio, Nunez, Jade, Outani, Oumaima, Nashidengo, Pueya Rashid, Shrestha, Ashish Lal, Jonker, Pascal, Kruijff, Schelto, Noltes, Milou, Steinkamp, Pieter, Varghese, Chris, Wright, Deborah, Abdur-Rahman, Lukman, Ademuyiwa, Adesoji, Adisa, Adewale, Osinaike, Babatunde, Seyi-Olajide, Justina, Williams, Omolara, Williams, Emmanuel, Pejkova, Sofija, Al Balushi, Zainab, Qureshi, Ahmad Uzair, Sayyed, Raza, Abo Mohsen, Mustafa, Abukhalaf, Sadi A., Cukier, Moises, Gomez-Fernandez, Hugo, Shu Yip, Sebastian, Vasquez Ojeda, Ximena Paola, Sacdalan, Marie Dione, Major, Piotr, Azevedo, José, Cunha, Miguel F., Zarour, Ahmad, Bonci, Eduard-Alexandru, Negoi, Ionut, Efetov, Sergey, Kochetkov, Viktor, Litvin, Andrey, Allen Ingabire, Jc, Bucyibaruta, Georges, Faustin, Ntirenganya, 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Déserts, Marc, André, Benoît, Slim, Karem, Verhaeghe, Romain, Police, Andrea, Girard, Edouard, Chebaro, Alexandre, Subayi Nkembi, Armande, Arnalsteen, Laurent, Ballouhey, Quentin, Mege, Diane, Jeandel, Clement, Duchalais, Emilie, Bouche, Pierre-Alban, Manceau, Gilles, Crétolle, Célia, Hervieux, Erik, Girard, Noémie, Seguin-Givelet, Agathe, Gaujoux, Sebastien, De Simone, Belinda, Boisson, Matthieu, Bergeat, Damien, Arnaud, Alexis P, Fredon, Fabien, Nappi, Francesco, Kassir, Radwan, Scalabre, Aurélien, Migliorelli, Federico, Ezanno, Anne-Cecile, Seeliger, Barbara, Vaysse, Charlotte, Charbonneau, Helene, Misrai, Vincent, Abbo, Olivier, Angeles, Martina Aida, Brunaud, Laurent, Demetrashvili, Zaza, Modabber, Ali, Wolf, Sebastian, Kamphues, Carsten, Höhn, Philipp, Glowka, Tim R., Rokohl, Alexander Christopher, Bork, Ulrich, Fluegen, Georg, Horch, Raymund E., Schmedding, Andrea, Schnitzbauer, Andreas, Eberbach, Helge, Schlager, Daniel, Spelsberg, Fritz, Keppler, Lena, Hecker, Andreas, Wolfer, Susanne, Ronellenfitsch, Ulrich, Nitschke, Christine, Peiper, Christian, Hakami, Ibrahim, Welter, Stefan, Nikolaieva, Karine, Roth, Andreas, Lindert, Judith, Gousias, Konstantinos, Rissmann, Anke, Linz, Valerie Catherine, Rahbari, Nuh, Rassweiler-Seyfried, Marie-Claire, Gut, Anna Eleonora, Gempt, Jens, Reim, Daniel, Wagner, Arthur, Albertsmeier, Markus, Keppler, Alexander M., Stoleriu, Mircea Gabriel, Saier, Tim, Stadler, Josef, Kaiser, Julia Christina, Brunner, Stefan M., Pfister, Karin, Herzberg, Jonas, Nowak, Kai, Reinhard, Tobias, Stavrou, Gregor A., Königsrainer, Alfred, Konrads, Christian, Quante, Markus, Laban, Simon, Pusch von, Silke, Hirschburger, Markus, Doerner, Johannes, Wiegering, Armin, Tampaki, Ekaterini Christina, Gutiérrez Ruiz, Alitza, Rodas, Alejandra, Portilla, Ana Lucía, Recinos, Gustavo, Aguilera-Arevalo, Maria-Lorena, Carrera, Jacqueline, Barrios Duarte, Amalia, Lowey, Megan, Barillas, Sabrina, Vaishnav, Dhaivat, Gorantlu Chowdappa, Raghunandan, Madabhavi, 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R, Nissi, Kannaiyan, Lavanya, Matai, Dr. Anil, Misra, Sanjeev, Bhende, Vishal, Muthu, Sathish, Ghosh, Indranil, Sharma, Abhishek, Bajaj, Ankur, Rajan, Shiv, Agarwal, Gaurav, Pawar, Pranay, Alexander, Philip, Vijayakumar, M, Hameed, BM Zeeshan, L, Badareesh, Chaudhry, Navneet Kumar, Baliarsing, Lipika, Dharap, Satish, Kulkarni, Amruta, Thyavihally, Yuvaraja, Pramesh, C S, Soni, Rajesh, Dube, Surya Kumar, Sharma, Shilpa, Singh, Harvinder, Bains, Lovenish, Ghodke, Rahul, Kumar, Ashwani, Sodhai, Vivek, Maji, Suvendu, Basu, Somprakas, Mahakalkar, Chandrashekhar, Kannan, Ravi, Mehraj, Asif, N, Ranganath, Phadnis, Ashish, Yadev, I, Kavalakat, Alfie, Mittal, Rohin, Vallam, Karthik Chandra, Akhavizadegan, Hamed, Rezghi Maleki, Esmaeil, Yousefzadeh Kandevani, Naser, Ikele, Hilary, McNestry, Catherine, Fleming, Christina, O’Brien, Stephen, Abd Elwahab, Sami, Davis, Niall, Javadpour, Mohsen, McDonnell, Brendan, O Connor, Clare, Bolger, Jarlath, Clancy, Cillian, Croghan, Stefanie M, Donlon, Noel, Cullinane, Carolyn, Creavin, Ben, Muheilan, Muheilan, Earley, Helen, Kabir, Syed Mohammad Umar, Fahadullah, Muhammad, Ryan, Éanna, Connelly, Tara, Zmora, Oded, Hashimoto, Daisuke, Alqudah, Majdi Ali, Alajalen, Amer, Omari, Rand Y., Ayasra, Faris, Qasem, Abdulrahman, Alawneh, Yazan, Ahmad, Amer, Aladawi, Omar, Alrayes, Bourhan, Haidar, Hanan, Husain, Shatha, Qassem, Faisal, Sumadi, Adnan, Al-Manaseer, Balqees Mahmoud, Alsunna, Zaid, Ra’ed, Hazim, Reyad Bani Hamad, Faten, Abuleil, Amro, Abou Chaar, Mohamad K., Jimaale, Elmi Ahmed Mohamed, Abu-Mehsen, Marah, Olaywah, Noor, Wafi, Omar, Ababneh, Hazim, Abu-Ismail, Luai, Khamees, Almu’atasim, Alkhatib, Ahmad, Bolatbekova, Raikhan, Kulimbet, Mukhtar, Nurgozhin, Talgat, Saliev, Timur, Zhussupov, Baurzhan, Almabayev, Ydyrys, Fakhradiyev, Ildar, Kaidarova, Dilyara, Tamoos, Khalil, Aqeelah, Ahmed, Khalefa mohammed, Alsnosy abdullah, Al maadany, Faraj, Alkadeeki, Ghadah, Gahwagi, Milad, Aldressi, Wafa, Amnaina, Mohamed, Alansari, Arowa hassan abdulrahman, Alkaseek, Akram, Yagoub, Ghozlan, Ben Amer, Anass, Salem, Marwa, Almugaddami, Ayman, Burgan, Dania, Abdelkabir, Mohammed, Alshareef, Khayriyah, Ben jouira, Rayet al islam, Meelad, Ayman, Bouhuwaish, Ahmad, Dwaga, Sumayya Essayah, Khalifa, Houda, Almiqlash, Bushray, Suliaman, Taha, Alawami, Mohammed, Elhajdawe, Fras, Aboazamazem, Hajir, Ellojli, Ibrahim, Msherghi, Ahmed, Saleh, Ismail Ali, Alayan, Mohammed, Roslani, April Camilla, Ndayishyigikiye, Marcel Didier, Munyika, Akutu, Plarre, Philipp, Borowski, David W, Nashidengo, Pueya Rashid, Noltes, Milou, Steinkamp, Pieter, Wells, Cameron, Teague, Rebecca, Elliott, Brodie, Kieser, David, Mohyieldin, Omar, Varghese, Chris, McIntosh, Nick, Haran, Cheyaanthan, Rennie, Sarah, King, Jasmin, Ha, Jeong, McGuinness, Matthew James, Adesanya, Opeoluwa, Olaogun, Julius, Akinmade, Akinola, Bwala, Kefas, Agbonrofo, Peter, Afolabi, Akinwale, Usang, Usang, Ekenze, Sebastian, Olori, Samson, Lawal, Taiwo Akeem, Seyi-Olajide, Justina, Okunlola, Abiodun, Williams, Omolara, Adisa, Adewale, Abdur-Rahman, Lukman, Kache, Stephen, Sale, Danjuma, Anyanwu, Lofty-John, Okereke, Chukwuma, Tolani, Musliu Adetola, Filipce, Venko, Todorovic, Lazar, Pejkova, Sofija, Stavridis, Sotir, Massoud, John George, Alsibai, Sareyah, Sultan, Rizwan, Altaf, Humera Naz, Bhatti, Abu Bakar Hafeez, Waqar, Shahzad Hussain, Aziz, Aliya, Kerawala, Asad Ali, Rai, Lajpat, Anwer, Mariyah, Tariq, Aiman, Ayub, Bushra, Niazi, Sami ullah, Naseem, Muhammad Yasir, Sarwar, Muhammad Zeeshan, Khokhar, Muhammad Imran, Zahid, Imdad Ahmad, Majid, Haroon Javaid, Talat, Nabila, Asif, Muhammad, Chaudhary, Muhammad Hamid, Farooq, Umer, Ahmad, Siddique, Mabood, Waleed, Bukhari, Syed Imran, Tariq, Muhammad, Yaqoob, Eesha, Javed, Saad, Usman Malik, Muhammad, Yaqoob, Hassan Nawaz, Cukier, Moises, Falcon Pacheco, Glenda Marina, Mas Melendez, Robinson, Paucar Urbina, Arazzelly Del Pilar, Rios Chiuyari, Jose, Otiniano Alvarado, Carlos Eduardo, Fuentes Rivera Lau, Lorena, Borda-Luque, Giuliano, Niquen-Jimenez, Milagros, Arias, Claudia, Zegarra, Sergio, Betalleluz Pallardel, Jenner, Ugarte Oscco, Regina Amparo, Mendiola, Gian, Carpio Colmenares, Yahaira Tatiana, Shiraishi Zapata, Carlos, Ortiz, Maria Rosa, Sacdalan, Marie Dione, Major, Piotr, Castro Borges, Filipe, Viveiros, Octavio, Serralheiro, Pedro, Santos-Costa, Paulo, Mendes, Filipa, Rocha Melo, Miguel, Cardoso, Paulo, Soares, Ana, Azevedo, José, Gonçalves Pereira, Rita, Silva, Nelson, Caiado, André, Sacras, Maria Luís, Azevedo, Pedro, Almeida-Reis, Rui, Cunha, Miguel F., Oliveira, João, Nogueiro, Jorge, Sampaio-Alves, Mafalda, Cidade Costa, Luciana, Baía, Catarina, Deus, Ana Cláudia, Branquinho, Rita, Marçal, André, Tojal, André, Makkai-Popa, Silviu Tiberiu, Mironescu, Aurel, Grama, Florin, Toma, Elena Adelina, Negoi, Ionut, Filipescu, Daniela, Bacalbasa, Nicolae, Motas, Natalia, Ionescu, Sebastian, Ginghina, Octav, Costea, Radu, Zarnescu, Narcis Octavian, Drasovean, Radu, Bonci, Eduard-Alexandru, Dimofte, Mihail-Gabriel, Porumb, Vlad, Kirov, Mikhail, Molitvin, Yegor, Litvin, Andrey, Pykhteev, Vadim, Raevskaya, Marianna, Efetov, Sergey, Butyrskii, Aleksandr, Alshahrani, Mushabab, Althumairi, Azah, Alzerwi, Nasser, Al Ameer, Ahmed, Madkhali, Tariq, Abddulrahman, Ghazwani, Salman, Ayoub, Abdu, Iskander, Othman, Ghunaim, Mohammed, Alharthi, Mohammed, Alzaidi, Turki M, Alyami, Mohammad, Al Amri, Abdulrahman, AlFakhri, Abdullah, Alhefdhi, Amal, Chowdhury, Sharfuddin, Nouh, Thamer, Alshehri, Ameen, Alzahrani, Abdulrahman, Alalawi, Dr Yousef, Awad, Selmy, Konate, Ibrahima, Ndong, Abdourahmane, Tendeng, Jacques, Teo, Nan Zun, Koh, Frederick, Košir, Jurij Aleš, Bele, Uros, Aqil, Sabra, Barrena López, Cristina, Sánchez Mozo, Ana, Rodriguez Infante, Antonio, Caja Vivancos, Patricia, Prieto, Mikel, Alberdi San Roman, Igor, Gomez Fernandez, Laura, Muñoz Vives, Josep Maria, Carreras-Castañer, Anna, Díaz-Feijoo, Berta, Sieira-Gil, Ramon, Turrado-Rodriguez, Victor, Sánchez López, Anna, Sánchez-Cabús, Santiago, Jimenez Toscano, Marta, Canals Sin, MªPilar, Laura, Saura García, Martin Sole, Oriol, Palazon Bellver, Pedro, Pérez-Bertólez, Sonia, Prat-Ortells, Jordi, Riba Martínez, Mireia, Rubio-Palau, Josep, Tarrado, Xavier, Nuñez, Jorge, Alonso Mendoza, Veronica, Bescós, Coro, Espin-Basany, Eloy, Espinosa-Bravo, Martin, Gil-Sala, Daniel, González-Suárez, Susana, Montferrer Estruch, Nuria, Porteiro Mariño, Lucia, Rodríguez-Tesouro, Ana, Rojas Portilla, Fabian, Tormos Pérez, M Pilar, Vives, Inmaculada, Garcia De Cortazar, Unai, Tudela, Kiara, Landaluce-Olavarria, Aitor, Estaire Gómez, Mercedes, Almoguera, Jorge, Ugarte-Sierra, Bakarne, Jimenez, Virginia, Bertrand, Marta, Cárdenas Puiggrós, Laura, Delisau-Puig, Olga, Garcia-Adamez, Jorge, Julià Bergkvist, David, Maldonado-Marcos, Eloy, Diego García, Lucia, Roldón Golet, Marta, Soto-Darias, Iván, Rahy-Martín, Aida Cristina, Enjuto, Diego, Ramos-Luengo, Adolfo, Delgado Fernandez, Juan, Lugo Duarte, Carolina, Marquez, Lucila, 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Signe Bremholm, Batista, Sylvia, Collado Expósito, María Mabel, Crespo, Aldo, D’óleo García, Claudio Samuel, Figueroa, Jatnna, Garcia-Dubus Rodriguez, U, Guzman, Lillian, Lopez, Ariela, Maletta Francisco, Leeany, Munoz, Herisardy, Perez Fernandez, Maricely Ambar, Rodríguez, Ada, Soto, Joel, Ubinas, Raul, Villegas, Aaron, Acra-Tolari, Ricardo, Beltran, Larissa, Betances, Luis Fernand, Díaz Vásquez, Pedro Pablo, Fernandez, Damaris, Figueroa Germosen, Jiomar Manuel, Mejia De la Cruz, Dolores, Ortiz De La Cruz, Fabio, Pelletier, Gabriela, Próspero Enrique, Rodriguez Pumarol, Suero Almanzar, Irina, Lincango-Naranjo, Eddy, Negrete Ocampo, José Ricardo, Sallam, Ibrahim, Sherief, Mohamed, Abdou, Mostafa, Abo Shanab, Ahmed, Abodeeb, Aya, Aboelkhel, Roger, Abosamak, Nour Eldin, Abouelnagah, Yossof, Adel, Dina, Ahmed, Sara, Alberkamy, Abdelrahman, Ali, Ahmed, Ashraf, Olfat, Darwish, Sara, El kharashy, Rasha, Elbadawy, Seifeldin, Elsaka, Alromisaa, Ewedah, Moataz, Ezz, Yara, Gadelrab, Ziyad, Hafez, Nour, Hafez, Youssef, Hassanin, Mohamed, Hussein Aly Salama Aly, Hamza, Ibrahim, Abdelrahman, Mahmoud Abo shabana, Alaa, Mourad, Mohamed, Mubarek, Kamilia, Omar, Samaa, Ragal, Marawan, Romany, John, Salem, Alaa, Samir Abdelaal, Ahmed, Shehata, Sameh, Shehata, Abdelrahman, Shenit, Karim, Yehia, Nermin, Khaled Mohamed Eid, Omar, Ibrahim Elsayed, Omar, Shehata, Mostafa Ahmed, Abd El-Ghani, Wael, Abd Elazeem, Hossam Aldein S., Abdalla, Shimaa, Abdel-Aleem, Mahmoud, Abdelfattah, Mahmoud, Abdelhafez, Mohammed, Abdelkarem, Mohamed M., Abubeih, Hossam, Ahmed, Nagm Eldin Abu Elnga, Ahmed, Ahmed, Ahmed Saad, Sarah, Ali, Abdelrahman Ahmed Abdelrahman, Elmaghraby, Khaled, Elsdfy, Shady, Eltayeb, Almoutaz, Essam, Esraa, Gadelkareem, Rabea, Ghoneim, Ahmed, Hamada Takrouney, Mohammed, Hasan, Ahmad, Hassanin, Mohamed Abdelghafor, Mahran, Wesam, Mahrous, Doha, Ragab, Abdelrahman, Sabry, Aya, Safwat, Hadeer, Saleh, Ahmed, Samir, Ahmed, Sayed, Esraa, Taher, Mohamed Gamal, Yousof, Ebrahim Ahmed, Youssef, Ahmed, Zein Elabedeen, Omar, Ali, Samar, Elbehairy, Gehad, Eleisawy, Mahmoud, Elgendy, Abdelrahman, Elhawary, Rewan, Hamdy, Mahmoud, Hassan, Gehad, Nowar, Mostafa, Sabry, Hesham, Tarek Said-elnaby, Ahmed, Zahed, Mohamed, Zahran, Mohamed, Zoghary, Ahmed Zaki, Atef, Mohamed, Abdelhamid, Mahmoud Hossameldin Saad, El Fiky, Lobna, ElGarhy, Ibrahim, Qassem, Mohamed, Wahba, Abdelrahman, Youssif Omar Fouad, Omar, Abdelsamed, Ahmed, Elsalhy, Mohamed, Eldesouky, Omnia, Wael Mostafa Khalil Bahi, Abdullah, Tawheed, Ahmed, Al-oribi, Saeid, Aly, Nuran Khaled, ElFiky, Mahmoud, Nabil, Ahmed, Samir Farahat, Ahmed, Soliman, Mostafa, Ghaly, Galal, Abbas, Alzhraa Salah, Ibraheem, Maher, Bakry, Abdelrahman, Jammal, Mohamed, M Makram, Abdelrahman, Adel abdelaty, Ahmed, Fayad, Elsayed A., Sallam, Moataz, Shehta, Ahmed, Elfeki, Hossam, Elsaid, Mahmoud, Mostafa, Mohamed, Sakr, Ahmed, Shetiwy, Mohamed, Tawakl, Noura, Yunes, Asmaa, Atallah, Khalid, Shetiwy, Mosab, Abdelmawla, Ahmed, Abdrabou, Ahmed, Abubakr, Asmaa, Al Gohary, Rawda, Elsabagh, Alaa, Elshabrawy, Enas, Hafez, Ahmed, Mikhail, Pola, Mohamed, Mervat, Nada, Ahmed, Omran, Janna, Salem, Osama, Selim, Salma, Shalaby, Ghada, Wahbah, Mahmoud, Zakaria Abdelbary, Eman, Zayan, Ahmad Helmy, Afify, Abdelrahman, Mohamed Ahmed, Mostafa, Abdeldayem, Hesham, Abdelkader Salama, Ibrahim, Ammar, Khaled, Ayoub, Islam, Gad, Emad Hamdy, Hammad, Essam, Macshut, Mahmoud, Sherif, Ahmed Elshawadfy, Shoreem, Hany, Soliman, Hossam Eldeen, Eldaly, Abdullah, Mashaly, Sarah, Abd-Elsalam, Sherief, Abdel-Elsalam, Wafaa, Morsy, Mohamed Sherif, Nasreddin, Mohammed, Sarsik, Sameh, Kams, Liisa, Rätsep, Tõnu, Riips, Karolin, Abebe, Kirubel, Asfaw, Fitsum, Eshete, Mahder, Gedefaw, Yetsedaw, Menjeta, Abeje, Muleta, Mahteme Bekele, Sefera, Sena, Teklu, Daniel, Tirfe, Leake, Worku, Bereket, Eado, Yegeremu, Negussie, Abraham, Woldemariam, Mersha Abebe, Alemu, Megersa, Azmach, Dawit, Mamo, Dr.Mickyas, Menkir, Abel, Woldemariam, Dereje, Wubishet, Estifanos, Supha, Melka, Abebe, Nebyou, Chanie, Abera, Gebre, Hiwot, Laeke, Tsegazeab, Mammo, Tihitena Negussie, Sahlu, Abat, Tiruneh, Abraham Genetu, Zewdneh, Betelhem, Fentaw, Jibril, Tabore, Ketema, Addisalem, Abreha, Tassew, Abdissa, Desalegn, Tesfaw, Mequannet, Asmamaw, Dawit, Bedane, Dereje, Bekele, Ephrem, Getie, Aderaw, Girma, Adissu, Shimelash, Dagim, Ayalew, Tewabe, Kassahun, Berhanu, Mulugeta, Esubalew, Sisay, Silamlak, Ibrahim, Adem, Mekete, Alem, Mohammed, Adnan Abdulkadir, Abdullahi, Yasir Younis, Adem, Ephrem, Siyoum, Eneyew Getachew, Zeleke, Ewunetu, Degefe, Derje Worku, Derilo, Habtamu, Eliyas, Nebiyu, Deressa, Yadani, Melese, Lemi, Muleta, Lemesa, Teshome, Abraham, Tesso, Birhanu, Gebrekirstos, Dr.Gebreagziabher, Pitkänen, Joel, Qian, Cheng, Sinikumpu, Jaakko, Dakpé, Stéphanie, Devauchelle, Bernard, Lavagen, Nolwenn, Bastard, François, Bin, Kim, Moukoko, Didier, Alshawared, Fadi, Beyrne, Carlos Daniel, Lugans, Laurene, Doussot, Alexandre, Onorati, Ilaria, Radu, Dana, André, Benoît, Marion, Herjean, Trilling, Bertrand, Boleslawski, Emmanuel, Noiret, Barbara, Aubry, Estelle, Subayi Nkembi, Armande, Christou, Niki, Usseglio, Julie, Jeandel, Clement, Denis, Waast, Duchalais, Emilie, Regenet, Nicolas, Rigaud, Jerome, Anract, Philippe, Dohan, Anthony, Cazelles, Antoine, Chamouni, Alexandre, Karoui, Mehdi, Mejean, Arnaud, Crétolle, Célia, Thouement, Clermidi, Pauline, Hervieux, Erik, Langlais, Tristan, Leonelli, Lorenzo, Thomin, Anne, Athiel, Yoann, Cathala, Nathalie, Levy-Zauberman, Yael, Macek, Petr, Mombet, Annick, Ollat, Didier, Fabrice, Chartier-Kastler, Emmanuel, Chereau, Nathalie, Melot, Charlotte, Turco, Célia, Chouillard, Elie, Boisson, Matthieu, Frasca, Denis, Livin, Marie, Mahmoud, Fedy, Sulpice, Laurent, Arnaud, Alexis P, Cazemajou, Clément Thierry, Nyangoh Timoh, Krystel, Renault, Annaëlle, Nappi, Francesco, Ezanno, Anne-Cecile, Cherkaoui, Zineb, Vix, Michel, Gornes, Hugo, Berthoumieu, Pierre, Misrai, Vincent, Pierre, Trocard, Angeles, Martina Aida, Del, Mathilde, Vancon, Antoine, Machemedze, Solomon, Muhemi, Roger, Ndizeye, Olivier, O’Connor, Jennifer, Tchoba, Simplice, Modabber, Ali, Schäfer, Benedikt, Wallqvist, Julia, Ziemann, Sebastian, Anthuber, Matthias, Broecheler, Tobias, Goßlau, Yvonne, Maksymiw, Florian, Sommer, Florian, Sommer, Björn, Loch, Florian N, Aghalarov, Ilgar, Braumann, Chris, Höhn, Philipp, Horn, Julian, Egger, Eva, Enderes, Jana, Strieth, Sebastian, Treede, Hendrik, Wittmann, Maria, Marche, Benedikt, Schulz, Sissy-Amelie, Fuchs, Hans, Bork, Ulrich, Meisel, Cornelia, Petzold, Andrea, Fluegen, Georg, Knoefel, Wolfram Trudo, Solodarenko, Oleksandra, Grützmann, Robert, Hackner, Danilo, Faqar-Uz-Zaman, Sara Fatima, Schnitzbauer, Andreas, Fung, Christian, Leiber, Christian, Neidert, Nicolas, Sandkamp, Richard, Schlager, Daniel, Strähle, Jakob, Spelsberg, Fritz, Becker, Johannes, Gonschor, Bernhard, Herbolzheimer, Marit, Keppler, Lena, Hecker, Matthias, Reichert, Martin, Sander, Michael, Schmidt, Götz, Schneck, Emmanuel, Kleeff, Jorg, Lorenz, Kerstin, Ronellenfitsch, Ulrich, Thomssen, Christoph, Dumpies, Christian W., Fischer, Isabel, Gessner, Michael, Klauke, Friederike, Schmidt, Birte, Vinz, Franziska, Sander, Johannes, Betz, Christian Stephan, Bewarder, Julian, Burg, Simon, Klatte, Till Orla, König, Daniela, Köpke, Leon-Gordian, Stangenberg, Martin, Roux, Frederic, Hakami, Ibrahim Abdullah, Mall, Julian W, Graeb, Christian, Huber-Strößner, Kristin, Pempe, Christina, Kelly, Kathrin, Siebert, Julia, Agrawal, Rachit, Gousias, Konstantinos, Qureischie, Homeira, Meyer, Frank, Rissmann, Anke, Turial, Salmai, Al-Nawas, Bilal, Battista, Marco Johannes, Heider, Julia, Mueller, Lena Katharina, Jentschura, Sina- Louisa Patrizia, Kowalewski, Karl-Friedrich, Rassweiler-Seyfried, Marie-Claire, Reissfelder, Christoph, Rotter, Nicole, Scherl, Claudia, Seyfried, Steffen, Fichter, Andreas, Gempt, Jens, Schäffer, Christoph, Wegmann, Helmut, Aghamaliyev, Ughur, Böcker, Wolfgang, von Ehrlich-Treuenstätt, Viktor H., Ladurner, Roland, Schlager, Justin Gabriel, Smolka, Wenko, Glowalla, Claudio, Schneidmueller, Dorien, Henkel, Karl Wilhelm, Stadler, Josef, Hölz, Katharina, Brunner, Stefan M., Prantl, Lukas, Herzberg, Jonas, Kröger, Marie, Niemeier, Andreas, Sras, Yara, Reinhard, Tobias, Löffler, Markus W., Steidle, Christoph, Dayan, Davut, Greve, Jens, Löbig, Niklas, Schochter, Fabienne, Wezel, Felix, Pusch von, Silke, Schmidbauer, Stefan, Boenicke, Lars, Degener, Stephan, Seiberth, Rose, Smit, Marieke, von Rundstedt, Friedrich-Carl, Germer, Christoph-Thomas, Lock, Johan, Lotz, Christopher, Schlesinger, Tobias, Schmid, Benedikt, Treutlein, Agnes, Agyeman-Duah, Nana Kwaku, Appiah, Enoch, Gakpetor, Delali, Minlah Allah, Stephen, Adu-Aryee, Nii Armah, Agboadoh, Nelson, Bediako Bowan, Antoinette, Brown, George Darko, Clegg-Lamptey, Joe-Nat, Fenu, Benjamin Sena, Kumassah, Philemon, Hussey, Romeo, Agbeno, Evans Kofi, Amoako-Boateng, Mabel, Debrah, Samuel, Doku, Dr Kingsley, Mensah, Philip, Nortey, Michael, Opandoh, Isabella Naa Morkor, Yigah, Makafui, Jiagge, Nuna, Acquaye, Jane, Agyemang-Prempeh, Akosua, Amo-Antwi, Kwabena, Amoah, Michael, Amoah, George, Aning, Daniel Gyawu, Annor Mintah, Dominic, Arthur, Joshua, Darko- Asante, Regina, Gaveh, Valerie, Gyamfi, Frank Enoch, Jonathan, Boakye - Yiadom, Konney, Thomas Okpoti, Kyei, Ishmael, Nimako, Boateng, Ofosu-Barko, Ben Blay, Osabutey, Anita, Sagoe, Robert, Yifieyeh, Abiboye, Ansong, George, Abdul-Mumin, Alhassan, Amadu, Munira, Azahares Leal, German, Buunaaim, Alexis, Cheyuo, Ernest, Daboo Salifu, Latif, Issaka, Adamu, Yakubu, Musah, Grypiotis, Ioannis, Papadopoulou, Triada, Korkolis, Dimitrios, Thomakos, Nikolaos, Dellaportas, Dionysios, Dimitra, Papalouka, Hadjizacharias, Theodoros, Konstadoulakis, Manousos, Massaras, Dimitrios, Vezakis, Antonios, Avgerinos, Konstantinos, Kechagias, Aristotelis, Ioannidis, Argyrios, Patelis, Nikolaos, Deskou, Eirini, Stamos, Nikolaos, Tasis, Nikolaos, Danias, Nikolaos, Selmani, Jonida, Kalamatianos, Theodosis, Stranjalis, George, Kondilis, Panagiotis, Kanellopoulou, Vasiliki, Larentzakis, Andreas, Papanikolaou, Vasileios, Potamianos, Spyridon, Triantafyllou, Tania, Panagiotou, Peter, Avramidis, Emmanouil, Bessias, Nikolaos, Tsiantoula, Paraskevi, Charalabopoulos, Alexandros, Kykalos, Stylianos, Kyros, Eleandros, Machairas, Nikolaos, Mastoraki, Aikaterini, Papalampros, Alexandros, Terras, Alexis, Tsourouflis, Gerasimos, Zografos, Constantinos, Antzaka, Christina, Falara, Areti, Perreas, Konstantinos, Rellia, Panagiota, Tasouli, Androniki, Skolarikos, Andreas, Tzelves, Lazaros, Theodorakis, Emmanuel, Karona, Paraskevi, Tzouganakis, Angelos, Chrysos, Emmanuel, Nikolouzakis, Taxiarchis, Tourountzi, Paraskevi, Al, Aggeliki, Kalfountzos, Christos, Arnaoutoglou, Eleni, Christodoulidis, Gregory, Gkolias, Nick, Hajiioannou, Jiannis, Krestinidis, Giorgos, Ntalouka, Maria, Saini, Fani, Skoulakis, Charalampos, Terzoudis, Christos Dimitrios, Zacharoulis, Dimitris, Δακής, Κωνσταντίνος, Filo, Eva, Kontopoulou, Konstantina, Patoulias, Ioannis, Astreidis, Ioannis, Christidis, Panagiotis, Loutzidou, Lydia, Mantevas, Antonis, Tatsis, Dimitris, Tsakiridis, Ioannis, Iordanidou, Eirini, Brolo, Estuardo, Gutiérrez Ruiz, Alitza, De León Lima, María Alejandra, Flores, Mario-Andrés, Morales, Steffanía, Rivera, Pablo, Rodas, Lesly, Santos, Victor, Sosa, Dianne, Barrios Duarte, Amalia, Talé-Rosales, Luis-Fernando, Villeda, Sergio Alejandro, Anicetti, Joshua, Lowey, Megan, Ardebol, Javier, Barillas, Kathia, Barillas, Sabrina, Recinos, Salvador, Hon, Sophie, Liu, Alex Qinyang, Liu, Shirley, Ip, Ho Wai, Mak, Brian, Mok, Chung Ying, Wong, Kiu Fung, Au-Yeung, Kit Ying, Chan, David Yuen Chung, Chiu, Wang Kei, Ho, Jacky Yan Kit, Kung, Janet Wui Cheung, Ling, Samuel Ka Kin, Lok, Hon Ting, Teoh, Jeremy Yuen-Chun, Wong, Randolph, Antal, Zsuzsanna, Bahrehmand, Kiarash, Sztipits, Tamás, Hidi, László, Piros, Laszlo, Rózsa, Balazs, Herczeg, György, Saftics, György, Kulcsicka-Gut, Judit, Sipos, Zsófia, Majmudar, Hardil, Madabhavi, Irappa, G S, Anitha, Kesarla, Venkatesh, Kumar Venkatappa, Sunil, P B, Hareesh, Shivashankar Chikkanayakanahalli, Santhosh, Sunil, Tanvi, Rajagopal, Niranjana, P L, Thirumanikandan, Mishra, Nitu, Wadhwani, Dr Rekha, Dhurwe, Ritika, Pushpalatha, Kameshwarachari, Raj, Sumit, Singh, Pooja, Kumar, Pankaj, Mittal, Yash, Panigrahi, Sibasish, Parija, Sucheta, Patra, Saroj, Sahu, Rabi, Sultania, Mahesh, Tripathy, Sujit, Kansay, Rajeev, Gupta, Sunil Kumar, Kaman, Lileswar, Salunke, Pravin, Singh, Kavindra, Rela, Mohamed, Goudar, Swati, B, Barani kumar P, Murugesan, Anandan, Subbian, Anbukkani, Kumar, Arvind, Chauhan, Tapan singh, Govil, Akhil, Gupta, Shubhra, Sharma, Ashish, Tiwari, Saurabh, Vishwani, Vartika, Evelyn. R, Nissi, Deb, Mainak, Jayaram, Harish, Nagpal, Pooja, Pathak, Prachi, Choudhary, Gautam Ram, Chugh, Ankita, Elhence, Abhay, Madduri, Vijay, Pandey, Himanshu, Saxena, Rahul, Sharma, Naveen, Shekhar, Shashank, Vishnoi, Jeewan Ram, Bhende, Vishal, Chatterjee, Debarshi, Ghosh, Indranil, Naskar, Upasana, Jain, Prateek, Jain, Deepak, Kewlani, Vishal, Priya, Noopur, Parijat, Anand, Anand, Akshay, Bajaj, Ankur, Chaurasia, Akhilanand, Enny, Loreno E., Kumar, Ambrish, Mishra, Brijesh, Pandey, Amita, Rajan, Shiv, Roy, Ashutosh, Sachan, Rekha, Sankhwar, Pushp, Singh, Uma, Singh, Urmila, Srivastava, Chhitij, Verma, Manju Lata, Yadav, Awdhesh, Agarwal, Gaurav, Chanthar, K.m.m.vishvak, Hoysal, Dileep, Mishra, Anjali, Batra, Nitin, Bhatti, Arun, Dhar, Tapasya, Dutta, Rohini, Haque, Parvez David, Jain, Ritu, Luther, Anil, Mahajan, Amit, Pargal, Dr Pinki, Samuel, Abhishek, Singh, Inderjot, Singh Grewal, Sarvpreet, Singhania, Anusha, Alexander, Philip, Thomas, Josy, Krishna, Sunil, Singh, Narinder, Agarwal, Sunny, Balasubramaniam, Srikant, Dharap, Satish, Mhamane, Rameshwar, Nirgude, Anand, Parab, Sandesh, Peswani, Amit, Sahu, Anjana, Samel, Sarika, Shah, Fagun, Abraham, Bejoy, Asari, Ashishkumar, Badhe, Vivek, Badhwar, Sanjiv, Bothara, Vipul, Dalal, Anuj, Date, Avinash, Deshpande, Mandar, Doshi, Anirudha, Gade, Maya, Gajjar, Shreyash, Ghugare, Dr bhavisha, Jain, Divakar, Jenasamant, Saumya Sekhar, Joshi, Vinay, Kalwadia, Neha, Kayal, Akshat, Kulkarni, Yogesh, Mistry, Rajesh, Mulchandani, Manoj, Parab, Dr. Mrunal, Pednekar, Abhinav, Rahmani, Faizan, Rajput, Sunil, Sandlas, Gursev, Sarkar, Hrishikesh, Shetty, Sanket sadanand, Shukla kulkarni, Anshumala, Thete, Raghavendraswami, Wasnik, Shruti, Dhumane, Parag, Sharma, Rahul Deo, Deshmukh, Anuja, Gupta, Stuti, Nayak, Prakash, Thiagarajan, Shivakumar, Tiwari, Virendra Kumar, Voppuru, Saiesh Reddy, Soni, Rajesh, Bajpai, Minu, Farooque, Kamran, Parshad, Rajinder, Sharma, Vijay, Bansal, Kuldeep, Bains, Lovenish, Bhardwaj, Rohit, Mittal, Abhishek, Ponnusamy, Sabarirajan, Ghodke, Rahul, Himani, Kumar, Ashwani, Gadekar, Anup, Panjwani, Taufiq, Maji, Suvendu, Basu, Somprakas, Kandwal, Pankaj, Kumar, Shashank, Poonia, Dharma Ram, Sadhasivam, Saravanan, Mahakalkar, Chandrashekhar, Choudhury, Yousuf, Das, Devishmita, Goala, Subhadra, Singha, S Thoibisana, Singha, Damayanti, Mehraj, Asif, Parray, Fazl, Shah, Raahil, Wani, Rauf, Hegde, Siddhi, Ankadavar, Dr.sushil, Bafna, Darshan, Lad, Parag, Chisthi, Meer, Jothi, Harihara, .C. Mathew, Godwin David, Abel, Livingston, Barla, Ravi Kishore, Benjamin, Santosh, Bliss, Jeremy, Ete, Geley, James, Deeptiman, Jesudason, Mark Ranjan, Karnan, Gomathi, Mark Samuel, Vasanth, Mittal, Rohin, Nathan, Senthil K, Selvaraj, Daniel, Surendran, Suraj, T D, Hariharan, Thangaraj, Santhosh Kumar, Thomas, Varghese, Dilmy, Mohammad Adya Firmansha, Pratama, Dedy, Sugiarto, Adhrie, Surya, Ilham Utama, Tango, Tamara, Hasyim, Andi, Susanti, Ade, Saputra, Teddy, Syarifuddin, Erwin, Islam, Andi Asadul, Anam, Khoirul, Sugianto, Julius Albert, Lestari, Mayang Indah, Amba, Erick Gamaliel, Apriawan, Tedy, Wathoni, Roidah Taqiyya Zahra, Widyastuti, Yunita, Yun Jufan, Akhmad, Etezadpour, Mohammad, Mehrad-Majd, Hassan, Rajaei, Parisa, Mehdizadeh, Mohammad, Soltani, Mina, Pour, Ali Moazami, Azarnia, Gholamreza, Alizadeh, Narges, Mokarami, Hossein, Tehrani, Shahrzad, Alborzi, Majid, Bagheri, Hamed, Eshraghi, Mohsen, Fatemi manesh, Hassan, Hejazi, Seyed fakhreddin, Pezeshki Modarres, Mahdi, Shafiee, Ali, Vafaeimanesh, Jamshid, Hosseini, Elahe, Nikoupour, Hamed, Bastaninejad, Shahin, Firouzifar, Mohammadreza, Motasaddi zarandy, Masoud, Yazdani, Nasrin, Yousefzadeh Kandevani, Naser, Mortazavi, SM Javad, Ahmadi, Sayedali, Khosravi, Mohammad Hossein, Vosoughi, Fardis, Golbakhsh, Mohammadreza, Al-Isawi, Ali, Al-Masood, Mohammed, Gahtan, Yarub, Ahmed, Abdullah, Hilmi, Ahmed, Muhssein, Haidar, McNestry, Catherine, Ekwere, Bosom, Essajee, Murtaza, Chan Chin, Bruno, Edwards Murphy, Amy, Fleming, Christina, Foley, Niamh, Gardiner, Padraig, Hechtl, Daniel, Kayyal, Mohd yasser, Lyons, Maria, O’Brien, Stephen, Ng, Mei Yee, Oduola, Oladayo, Aljohmani, Lylas, Nugent, Timothy, Harris, Johnathon, Kearney, David, Keenan, Robert Anthony, Nolan, Deirdre, Salloum, Croghan, Stefanie M, Donohoe, Emma, Larkin, John, Lynch, Thomas Hugh, Manecksha, Rustom, Nagassima, Katharina, Barry, Mary, Cullinane, Carolyn, Dowdall, Joseph, Hurson, Conor, Kelly, Orlaith, Kennelly, Rory, Kiernan, Aoife, Murphy, Ben, Njeze, Nwabundo, Reynolds, Ian Sean, Winter, Des, Ravi, Akshaya, Ridgway, Paul, Fowler, Amy, McAnena, Peter, Bahadoor, Muhammad Usaama, Kabir, Syed Mohammad Umar, Khalid, Mohamed Hamed, Mujtaba, Syed Nadeem, Sarwar, Muhammad assam, Sugrue, Michael, Varzgalis, Manvydas, Jones-Whiting, Larne, Lim, Seantee, Ryan, Éanna, Sara, Al-Mukhaizeem, Youssef, Crowley, Clare, Flanagan, Michael, Fogarty, Amy, Glynn, Orna, Hill, Rhodri, Khalid, Muhammad Abdullah, Majeed, Zubair, McCullough, Peter, Neary, Peter, Noone, Anthony, O’Kelly, John, Abu abed, Arsan, Haim, Nadav, Hershkovitz, Yehuda, Majadla, Omar, Rabin, Igor, Zmora, Osnat, Demma, Yonatan Avraham, Fishman, Yuri, Farkas, Amicur, Gozal, Yaacov, Greenman, Dmitry, Ostrovsky, Israel Alexander, Pardes, Rivka, Shahar, Tal, Teren, David, Yahud, Reuven, Yellinek, Shlomo, Cianci, Pasquale, Minafra, Marina, Restini, Enrico, Bussolin, Edoardo, De Prizio, Marco, Sulce, Rezart, Poiasina, Elia, Antonacci, Filippo, Arena, Alessandro, Belvedere, Angela, Bernagozzi, Fabio, Boussedra, Safia, Cescon, Matteo, Cipolli, Alessandro, Daddi, Niccolo’, De Crescenzo, Eugenia, De Iaco, Pierandrea, Del Gaudio, Massimo, Della Gatta, Anna Nunzia, Droghetti, Matteo, Giorgini, Federico A., Lanci Lanci, Antonio, Masetti, Michele, Minni, Francesco, Morezzi, Daniele, Perrone, Anna Myriam, Pignatti, Marco, Puglisi, Silvana Bernadetta, Rottoli, Matteo, Schiavina, Riccardo, Serenari, Matteo, Serra, Margherita, Tesei, Marco, Violante, Tommaso, Aspide, Raffaele, Carretta, Alessandro, Conti, Alfredo, De Vita, Carla, Friso, Filippo, La Corte, Emanuele, Rosetti, Vittoria, Sturiale, Carmelo, Donati, Davide Maria, Palmerini, Emanuela, Berselli, Bruno, Bolognesi, Silvia, Farnia, Francesco, Maremonti, Pietro, Razzaboni, Alessandra, La Mendola, Roberta, Arrigoni, Giulia, Baiocchi, Gian Luca, Molfino, Sarah, Panciani, Pier Paolo, Sartori, Enrico, Zanin, Luca, Perrone, Fabrizio, Cappellani, Alessandro, Giaquinta, Alessia, Gioco, Rossella, Veroux, Pierfrancesco, Cianci, Antonio, Lo Giudice, Arturo, Russo, Giorgio Ivan, Sarpietro, Giuseppe, Scandura, Carmen Emanuela, Barca, Ida, Carnevali, Adriano, De Paola, Gilda, Giannaccare, Giuseppe, Sammarco, Giuseppe, D’Andrea, Marcello, Tosatto, Luigino, Mucilli, Felice, Muraglia, Angelo, Giuliani, Domenico Benvenuto, Segalini, Edoardo, Daniele, Alberto, Gelarda, Enrico, Olearo, Elena, Puppo, Andrea, Testa, Valentina, Porta, Andrea, Birindelli, Arianna, Bernabei, Massimiliano, Feo, Carlo V., Virgilio, Edoardo, Bartolini, Ilenia, Bottari, Andrea, Checcucci, Carlotta, De Vincenti, Rosita, Fambrini, Massimiliano, Fortuna, Laura, Gallo, Oreste, Maltinti, Gherardo, Taddei, Antonio, Michelagnoli, Stefano, Maccagnano, Giuseppe, Pesce, Vito, Ercolani, Giorgio, Fappiano, Francesca, Barberis, Andrea, Filauro, Marco, Santoliquido, Matteo, Aprile, Alessandra, Barra, Fabio, De Rosa, Raffaele, Ferrero, Simone, Sparavigna, Marco, Vagge, Aldo, Gambardella, Denise, Tedesco, Manfredo, Spampinato, Marcello Giuseppe, Chiarelli, Marco, Grandi, Samuele, Lenzi, Riccardo, Muscatello, Luca, Germano’, Antonino Francesco, Giani, Alessandro, Bissacco, Daniele, Cassinotti, Elisa, Pignataro, Lorenzo, Torretta, Sara, Armellin, Daniele, Basato, Silvia, Carrano, Francesco Maria, Colombo, Giovanni, De Lucia, Francesca, De Virgilio, Armando, Ferreli, Fabio, La Raja, Carlotta, Milana, Flavio, Rossi, Vanessa, Russo, Elena, Tamburello, Sara, Zerbi, Alessandro, Bona, Davide, Adamoli, Laura, Ansarin, Mohssen, Chu, Francesco, De Berardinis, Rita, Pietrobon, Giacomo, Sedda, Giulia, Caputo, Maria, Cellerino, Paola, Crespi, Michele Achille, Danelli, Piergiorgio, Ferrara, Francesco, Baccellieri, Domenico, Candiani, Massimo, Casiraghi, Arianna, Cipriani, Federica, De Nardi, Paola, Mortini, Pietro, Nocera, Gianluca, Pozzoni, Mirko, Ruffolo, Alessandro Ferdinando, Spina, Alfio, Barberio, Cristina, Beretta, Luigi, Cavenago, Francesca, Fresilli, Stefano, Landoni, Giovanni, Lombardi, Gaetano, Bonomi, Stefano, Guaglio, Marcello, Sala, Laura, Segattini, Silvia, Piccoli, Micaela, Migliore, Marco, Sasia, Diego, Cereda, Marco, Dell’Oro, Cristina, Fogliati, Alessandro, Tamini, Nicolò, Castaldi, Antonio, Bracale, Umberto, Lionetti, Ruggero, Pagano, Gianluca, Peltrini, Roberto, Pirozzi, Nello, D’amico, Maria, Izzo, Francesco, Marra, Ester, Marte, Gianpaolo, Bianco, Francesco, Cappiello, Antonio, Iovino, Claudio, Menna, Maria Paola, Romano, Francesco maria, Rossi, Settimio, Sciaudone, Guido, Ascari, Francesca, Bellora, Paolo, Cerri, Cristina, D’Aloisio, Giordana, Ferrari, Maurizio, Chioffi, Franco, Ciccarino, Pietro, Nezi, Giulia, Bissolotti, Guido, Di Donna, Mariano Catello, Licari, Leo, Salamone, Giuseppe, Toia, Francesca, Annicchiarico, Alfredo, Berretta, Roberto, Capozzi, Vito Andrea, Freyrie, Antonio, Frusca, Tiziana, Arici, Vittorio, Bozzani, Antonio, Filardo, Matteo, de Manzoni Garberini, Andrea, Cauteruccio, Michele, Caristo, Giuseppe, Calabrò, Marcello, Andreani, Lorenzo, Antonio, D’arienzo, Berrettini, Stefano, Colangeli, Simone, Cremonini, Camilla, Dallan, Iacopo, Di Franco, Gregorio, Korasidis, Stylianos, Musetti, Serena, Neri, Carlo Maria, Palmeri, Matteo, Picariello, Miriana, Statuti, Erica, Tartaglia, Dario, Pinotti, Enrico, Basso, Stefano Maria Massimiliano, Ubiali, Paolo, Coiro, Saverio, Mele, Simone, Corbellini, Carlo, Masciandaro, Antonio, Carannante, Filippo, Denaro, Vincenzo, Mazzotta, Erica, Zampogna, Biagio, Cinquepalmi, Matteo, Del Basso, Celeste, Guglielmo, Nicola, Meniconi, Roberto Luca, Sinibaldi, Giovanni, Agnes, Annamaria, Belia, Francesco, Bianchi, Valentina, Cozza, Valerio, Fico, Valeria, Fransvea, Pietro, La Greca, Antonio, Litta, Francesco, Pascale, Marco Maria, Silvia, Tedesco, Benevolo, Maria, Campo, Flaminia, Dona’, Maria Gabriella, Marchesi, Paolo, Mastroianni, Riccardo, Mazzola, Francesco, Moretto, Silvia, Petruzzi, Gerardo, Pichi, Barbara, Tuderti, Gabriele, Bellato, Vittoria, Grande, Michele, Petagna, Lorenzo, Sensi, Bruno, Bruzzaniti, Placido, Ciccarone, Flavia, Cicerchia, Pierfranco Maria, Cirillo, Bruno, D’ambrosio, Giancarlo, De Toma, Giorgio, Familiari, Pietro, Fonsi, Giovanni Battista, Pata, Francesco, Picchetto, Andrea, Salvati, Maurizio, Valentini, Valentino, Zambon, Martina, Zancana, Giuseppa, Zuppi, Emma, Ibrahim, Mohsen, Menna, Cecilia, Rendina, Erino Angelo, Accarino, Giulio, Giancarlo, Accarino, Froiio, Caterina, Copelli, Chiara, Di Maio, Pasquale, Giudice, Marco, Altana, Cristian, Ciccarello, Sandro, Cossu, Maria Laura, Dessole, Francesco, Dettori, Salvatora, Madonia, Massimo, Petrillo, Marco, Piredda, Franco, Rizzo, Davide, Scognamillo, Fabrizio, Soma, Damiano, Tanca, Anna Rita, Marano, Luigi, Pesce, Anna Lisa, Piccioni, Stefania Angela, Resca, Luca, Roviello, Franco, Abrate, Alberto, Clarizia, Guglielmo, Franzini, Marco, Fratto, Antonio, Grechi, Alessandro, Scarnecchia, Elisa, Maiuri, Vincenzo, Dalprà, Francesca, Battistella, Enrico, Romano, Maurizio, Aizza, Giada, de Manzini, Nicolò, Drigo, Davide, Mastronardi, Manuela, Palmisano, Silvia, Bardelli, Laura, Borroni, Giacomo, Livraghi, Lorenzo, Palumbo, Mara, Zullo, Alessandra, Vignotto, Chiara, Caravati, Andrea, De Cristofaro, Carlotta, Giuliani, Tommaso, Guglielmi, Alfredo, Pedrazzani, Corrado, Butturini, Giovanni, Moretto, Gianluigi, Mastriale, Francesco, Olmi, Stefano, Kushikata, Tetsuya, Oyama, Tasuku, Kamiyama, Mizue, Tarao, Kentaroh, Yamada, Takayuki, Shiga, Toshiya, Deguchi, Yoshihiko, Hoshino, Tatsuki, Inoue, Hiroyuki, Ito, Shingo, Takano, Emi, Yamamoto, Masae, Matsuki, Yuka, Matsumoto, Takashi, Sawada, Atsushi, Sato, Kozo, Makino, Jun, Mizota, Toshiyuki, Yonekura, Hiroshi, Ishikawa, Haruka, Kaiho, Yu, Ogawa, Munehiro, Endo, Shunji, Fujiwara, Yoshinori, Kubota, Hisako, Okada, Toshimasa, Hisamatsu, Yoji, Michiura, Taku, Satoshi, Okazaki, Fujita, Tomoyuki, Fukushima, Satsuki, Otsuka, Yuji, Sawada, Ikumi, Miyamoto, Morikazu, Isada, Tetsuro, Bani Amer, Qaed, Fujimoto, Yuki, Kuratani, Norifumi, Takada, Misa, Noro, Shusaku, Kuroda, Naoto, Okamura, Yukiyasu, Uesaka, Katshuhiko, Kuroda, Kento, Abe, Nobutsugu, Ando, Tadao, Hirano, Kouichi, Kobayashi, Yoichi, Motoyasu, Akira, Noguchi, Hikari, Tajima, Atsushi, Toyama, Satoshi, Uchida, Tokujiro, Furukawa, Yuri, Hasumi, Yoko, Iida, Katsuyuki, Ikeda, Tatsuhiko, Kuzuhara, Shigeki, Yamamoto, Naoya, Yamamoto, Mari, Yokota, Toshiya, Yoshioka, Yuki, Kawai, Akira, Nakata, Yoshinori, Sawamura, Shigehito, Kobayashi, Takayuki, Alqudah, Majdi Ali, Alrabadi, Mera, Owais, Qais, Smadi, Aseel, Abunawas, Huthifa, Alhawatmeh, Mohammad, Alwardat, Abdel Rahman Mohannad Ahmad, Dhoon, Slsabela, Jaradat, Enas, Mubaydeen, Teeba, Alzraikat, Sayel H., Omari, Rand Y., Suradi, Haya H., Al Abdallah, Murad, Al Bdour, Zakaria, Al-thaher, Mohammad, Alnajjar, Tareq, AlZaatreh, Mohammad, Ayasra, Faris, Ghayada, Ibrahim, Hasanein, Khaled Moh’d Ahmed, Hassouneh, Anas, Hijazeen, Raid, Khasawneh, Barihan, Semrin, Qusai, Theab, Mohammad, Abazeed, Alaa, Alkurdieh, Moh’d Mujahed, Hammouri, Mohammad, Khader, Sereen, Abu Obead, Hamza, Abudari, Hadeel, Al-azzeh, Nimer, Al-Darabah, Ali, Al-Qannas, Mohammad, Ashour, Subhi, Chabaan, Reem, Fawzi, Ahmad, Haij, Manal, Hassouneh, Esraa, Ibrahim, Zainab, Mohamed, Ishak, Qandeel, Mahmoud, Qassem, Faisal, Shorman, Marwan, Nofal, Sandra, Salameh, Mohammed, Sanjuq, Ghaidaa, Sharabi, Alaa, Sweiti, Alaa, Baninasr, Eman, Abuleil, Amro, Abou Chaar, Mohamad K., Al-latayfeh, Motasem, Al-Shudifat, Abdel-Ellah, Shaikh Ahmad, Abd Almonem, Abu Abed, Laith, Allouzi, Mohammad, Almi’ani, Sari, Alsaiad, Abdulhakim, Daoud, Maher, Dawod, Omar, Fadli, Saba, Jimaale, Elmi Ahmed Mohamed, Qulaghassi, Zaki, Al-howthi, Mohammed, Ababneh, Laila, Ababneh, Roba, Al Khassawneh, Ahmad, Al Sharie, Ahmed, Al-Dabaa, Tawfik, Al-Jarrah, Salsabeel, Alshannaq, Qutaiba, Alsulaiman, Rima, Audat, Ziad, Bdour, Saja, Khatatbeh, Ro’a, Marji, Fares, Abu Ismail, Dima.Y, Abu-Ismail, Luai, Alzoubi, Mai, Alzoubi, Malak, Hussein, Hasan, Rawashdeh, Shireen, Ababneh, Adnan, Abu-Eisheh, Basil, Al Shurman, Hana’, Al-atiyah, Hussam, Aljaiuossi, Anas, Hamdoni, Sara, Kulimbet, Mukhtar, Sakhov, Orazbek, Fakhradiyev, Ildar, Tanabayeva, Shynar, Zhussupov, Baurzhan, Amrayev, Sultan, Kukubassov, Yerlan, Parker, Robert, Mwaria, Claude, Kibunyi, Muthoni, Mailu, Claire, Osea, Lydia, Hirsi, Omar, Dashti, Mustafa, Aldalal, Shuaib, Alozairi, Ous, Al-Shaiji, Tariq, Alhunaidi, Omar, Aljewaied, Ali, Farag, Ahmed, Termos, Salah, Sivins, Armands, Apse, Ingus Arnolds, Kaminskis, Aleksejs, Pāvulāns, Jānis, Itani, Rania, Owiedat, Mustafa, Antonios, Ingrid, Milan Moussa, Rita, Abdel Sater, Ali H., Souleiman, Bassem, Ghiya, Peter, Fakih, Ghinwa, Tamoos, Khalil, Abdulrahman, Taha, Omar Abunaaja, Hayat, Al Gasi, Abd El Jawad, Al maadany, Faraj, Alsaeiti, Sara, Elkhafeefi, Fatimah, Alhouni, Tarek, Alkeelani, Hana, Alkuwafi, Rauoof, Elbargathe, Osama, Elfadli, Mustafa, Elmahgoub, Asma, Alansari, Arowa hassan abdulrahman, Alhaje, Awatif, Haron, Aaya, Alsuwiyah, Suhir, Khel, Samer, Yousef, Rowaida, Abuhlaiga, Ma’aly, Abushahma, Ahmed omar, Aldelensi Alzubi, Alhosen Saleh M, Alnehum, Mohamed alnaser, Alzedam, Ahmad, Matoug, Faisel, Mohammed, Burooj, Sawalem, Mohamed, Kamoka, Elhusain, Salamah, Abdulrauf, Abdeewi, Saedah, Eshnaf, Mabroka, Yahmad, Mohammad, Aljuroushi, Omar, Attia, Hajer, Emran, Ayyah, Samer, Ashraf, Abdullah, Duha milad, Ben esmael, Esraa, Benmasoud, Fatma, Debri, Laila, Younis, Balkees, Elmabrouk, Amna, Hasan, Ameerah Mahdi Abraheem, Suliaman, Taha, Alawami, Mohammed, Alshareea, Entisar, Aribi, Tomather, Lamari, Amani hamid, Mufth, Mohammed, Aburima, Sarah, Al shukri, Asmaa, Alarabi, Rehab, Alelwany, Aisha, Bashir, Rasha, Elhadi, Ahmed, Elkouba, Esraa, Ellojli, Ibrahim, Elmsherghi, Nabiha, Haidar, Arwa, Helal, Hala, Kriem, Eslam, Turshani, Laila, Alayan, Mohammed, Ben Hasan, Hayat, Shaban Ben Hasan, Najat, Shaban Ben Hasan, Rabab, Dambrauskas, Zilvinas, Dekeryte, Inga, Koženiauskaitė, Akvilė, Maleckas, Almantas, Venclauskas, Linas, Zilinskas, Justas, Syminas, Vilius, Aliosin, Oleg, Cizauskaite, Agne, Jurgaitis, Jonas, Mikutaitis, Vytenis, Samalavicius, Narimantas Evaldas, Slepavicius, Algirdas, Vasiliauskas, Bernardas, Dulskas, Audrius, Cekauskas, Albertas, Gulla, Aiste, Zelvys, Arunas, Noël, Audrey, Rajaonarivony, Maheriandrianina Fanambinana Voahary, Andriantsoa, Herimampionona E, Samison, Luc Hervé, Tsiambanizafy, Guillaume Odilon, Solo, Corinne Eulalie, Safiry Andofenohasina, Fanonjomahasoa, Sablon Herinirina, Angelin, Das, Andre, Osman, Mohd Firdauss, Soh, Jien Yen, Zakaria, Zaidi, Chan, Kheng Hooi, Johan, Syamim, Mah, Jin Jiun, Subramaniam, Sentilnathan, Ibrahim, Mohd Razali, Nazimi, Abd Jabar, Bal, Pavin, Fadzli, Ahmad nazran, Jamaris, Suniza, Lee, Yeong Sing, Lim, Jeffery Zk, Moh Pauzi, Siti Farhan, Nair, Ashvin Krishna, Ng, Doris Sin Wen, Ng We Yong, Yuki Julius, Roslani, April Camilla, Saaid, Rahmah, Sethi, Neha, Syed Jafer Hussain Zaidi, Syeda Nureena, Teoh, Li Ying, Munjih, Islah, Sainal, Mohd Yusof, Sarif, Mat Salleh, Chua, Richelle, Ahmad, Abdul Rauf bin, Lau, Yii Ling, Liew, Ka Yee, Palayan, Kandasami, Abdul Rahman, Noorneza, Firman, Fatin, Hazleigh, Nik Mohd, Mohd Miswan, Mohd Fairudz, Mohd Zahid, Akmal Zulayla, Yahaya, Mohd Yusoff bin Yahaya, Yusoff, Ahmad Ramzi, Darryl, Brincat, Svetlana, Caruana, Clifford, Chircop, Daniel Mario, Czok, Viktoria, Muscat, Esther, Roshan, Mohsin Hassan Khan, Schembri, Nicholas, Jonathan Rubén, Cedillo Rodrìguez, Rojas Aguilar, Antonio, Sosa Duran, Erik Efrain, Arroyo, Diego, Martinez-Said, Hector, Medina-Franco, Heriberto, Pérez de León Vázquez, Martha Patricia, Soto Hernández, Fidel, Stenner, Juan Ignacio, Zuloaga Fernandez del Valle, Carlos Jose, Colunga Tinajero, Carlos Andres, Yanowsky-Reyes, Guillermo, Camacho Gomez, Aldo, Cueva-Martinez, Esteban, Durán Anguiano, Oscar, García Castillo, Miguel, Gonzalez Ojeda, Alejandro, González-García de Rojas, Erick Alonso, Guzman Barba, Jose Aldo, Ibarrola Peña, Juan Carlos, Íñiguez Martínez, César, Llamas- Macias, Francisco Javier, Ambriz Gonzalez, Gabriela, Morales valencia, Eduardo, Santos, Blanca, Torres Cisneros, Juan Roberto, Bozada-Gutiérrez, Katya, Alvarez, Maria Regina, de la Rosa Abaroa, Marco Antonio, Hernandez, Roberto, Bernardo, Anaya, Ernesto, Arceo-Olaiz, Ricardo, Lopez Flores, Sonia, Esparza Arias, Nereida, Romero Bañuelos, Esmeralda, Salcedo-Hernández, Rosa, Buerba, Gabriela Alejandra, Chan, Carlos, Garay Lechuga, Daniel, Hinojosa, Carlos, Mercado, Miguel Ángel, Peña Gómez Portugal, Emmanuel, Posadas-Trujillo, Oscar Emmanuel, Hernandez Skewes, Karla Yareli, Licona-Meníndez, Roque Delfino, Romero Lechuga, Fernanda, Roque, Oscar, Núñez-González, Roberto Ángel, Alvarez Manilla Orendain, Alfonso, Garcia, Felipe, González León, Juan Antonio, Guzman, Marlin, Herappe, Dorihela, Lerma, Ricardo, Mendoza Pedraza, Fabián Hilario, Noguez Castillo, Monica, Resendiz, Jose Anatolio, Fernandez Rios, Laura Elena, Frigerio, Pamela, Garcia, Iset, Mendoza Frías, Gloria Isela, Anzures Mendoza, Alejandra, Hdez Miguelena, Luis, Zarate Saenz, David, Zavala gonzalez, Miguel angel, Andrade González, Francisco, Cortes, Ludivina, Gurghiș, Radu, Sanjaa, Burmaa, Ait benhamou, Rita, Rghioui, Mounir, Saaf, Sarra, Letrache, Ahmed, Zekhnini, Meryem, Abichou, Wijden, Baroudi, Salma, Hassoun, Chiraz, Zaim, Ouijdane, Arkha, Yasser, Bechri, Hajar, Benchekroun Belabbes, Meryem, Benslimane, Zaineb, Boualila, Lina, El Ouahabi, Abdessamad, Essakalli Hossyni, Leila, Tagmouti, Adam, Belkhadir, Zakaria Houssaïn, Benkabbou, Amine, Boutayeb, Saber, El Ahmadi, Brahim, Ghannam, Abdelilah, Kabbaj, Taha, Majbar, Anass Mohammed, Ndayishyigikiye, Marcel Didier, Ndatewapo, Fillipus, Njuki, Peter Ngungi, Abrahams, Jenevive, Bhusal, Subarna, Dwa, Yam, Bloemers, Frank, Besselink, Marc, van Amstel, Paul, Smeele, Ludi, Harlaar, Niels, van der Burg, Sjirk, Noltes, Milou, Steinkamp, Pieter, Franken, Josephine, Oosterling, Steven, Nolte, Peter, Alwayn, Ian, Braat, Andries, Goudsmit, Ben, van de Leemkolk, Fenna E.M., Albers, Kim, Van Goor, Harry, van Ginhoven, Tessa M., Schweitzer, Donald, Leclercq, Wouter, Vancoillie, Peter-Jan, Konsten, Joop, den Boer, Frank, Djamali, Kaveh, Ghamri, Naji, Joseph, Reece, Lie, Samuel, Olliff, Sue, Wood, Daniel, Furkert, Chris, Teague, Rebecca, Lim, Eric, Mclauchlan, Jared, Ailabouni, Ramez, Alqassab, Mohammed, Hawkins, Robyn, Baker, Joseph, Ou, Cindy Xin Yi, Singh, Vidit, Frunt, Brytt, Lakshman, Prashant, Henderson, Nigel, Ha, Jeong, Haimona, Maira, Jury, Steffanie, Weeratunga, George, Witcomb Cahill, Henry, Abdussalam, Hameedat Opeyemi, Ahmed, Aminat Olayinka, Adeyeye, Ademola, Kayode-Nissi, Victor, Kadiri, Innih, Oduah, Stella, Olaogun, Julius, Abdull, Mohammed, Abdullahi, Mohammed Kabir, Ja’afar, Abubakar Bappah, Ja’afaru, Umma Hani, Yakubu Mohammed, Husseini, Edetanlen, Ekaniyere, Iribhogbe, Oseihie, Irowa, Omorodion, Nwashilli, Nnamdi, Obahiagbon, Osarobo, Onyeagwara, Ngozi, Oseghale, Eustace, Osemwegie, Osarenkhoe, Osho, Philip, Akanni, Bolaji, Ezomike, Uchechukwu, Okoro, Kelechukwu, Okwara, Blasius, Abdulsalam, Khalifa, Agida, Eyaofun, Ajibola, Hafees, Benard, Adeka, Buba, Amina, Eniola, Sefiu, Isah, Aliyu, Olute, Anne, Osagie, Olabisi, Pius Ogolekwu, Idoko, Ademola, Samuel, Afuwape, Oludolapo, Daodu, Israel, Egbuchulem, Ifeanyichukwu Kelvin, Lawal, Taiwo Akeem, Nwaorgu, Onyekwere, Obadan, Izegaegbe, Odeyemi, Olubunmi, Ogundoyin, Omowonuola, Okere, Oghenekevwe, Oladiran, Ajibola, Olagunju, Naomi, Olawoye, Olayinka, Olusanya, Adeola, Oyelakin, Oyeleye, Ugwu, Ebere, Ademuyiwa, Adesoji, Atoyebi, Oluwole, Bode, Chris, Chibuike George, Ihediwa, Ezenwankwo, Francis, Fatuga, Adedeji, Ladipo-Ajayi, Oluwaseun, Ojewola, Rufus Wale, Okunowo, Adeyemi, Seyi-Olajide, Justina, Ugwu, Aloy Okechukwu, Adebara, Idowu, Adeyemo, Olabisi, Banjo, Oluseyi, Obateru, John, Ojo, Owolabi, Okunlola, Abiodun, Oluwafemi, Fatudimu, Adelaja, Aderinsola, Atobatele, Kazeem, Ayodele, Olabamidele, Bello, Funmi, Omisanjo, Olufunmilade, Aderounmu, Adewale, Adisa, Adewale, Ajekwu, Temitope, Ajekwu, Samuel, Akeem Aderogba, Adeleke, Balogun, Simon, Ojo, Olugbenga, Olasehinde, Olalekan, Olugbami, Adebayo, Wuraola, Funmilola, Mohammed, Tajudeen, Afolabi, Abdulrahman O., Aremu, Isiaka, Ibraheem, Gbadebo, Odeyemi, Peter Olalekan, Olabinjo, Afusat, Raji, Hadijat Olaide, Salawu, Hafeez, Uche-Okonkwo, Kenechukwu, Anipole, Olalekan, Adesina, Oluwaseyi, Enwerem, Kenneth, Isichei, Mercy, Aghadi, Ifeanyi, Kache, Stephen, Lawal, Jamila, Taingson, Matthew, Yusuf, Nuhu, Sale, Danjuma, Takai, Idris Usman, Aji, Sani Ali, Anyanwu, Lofty-John, Bello-Muhammad, Nafisatu, Garzali, Ibrahim Umar, Hasheem, Muhammad Ghazali, Hassan, Sadiq, Ibrahim Usman, Mustapha, Magashi, Mahmoud Kawu, Mukhtar, Ibrahim Aliyu, Nwachukwu, Callistus, Suleiman, Ibrahim, A, Maryam, Mahmood, Farrukh, Salihu, Mohammed, Okereke, Chukwuma, Alegbeleye, Justina Omoikhefe, Awopeju, Abimbola, Fyneface-Ogan, Sotonye, Kasso, Terhemen, Onwuagha, Ijeoma, Salami, Babatunde, Ajagha, Okeoghene, Awaisu, Mudi, Nwabuoku, Stanley Emeka, Oyelowo, Nasir, Tolani, Musliu Adetola, Filipce, Venko, Rendevski, Vladimir, Shuntov, Blagoj, Todorovic, Lazar, Jovanovska, Katerina, Nikolovska, Bisera, Peev, Igor, Asha, Al Amri, Ayman, Al Badaai, Ghalib, Al Balushi, Zainab, Al Farsi, Maather, Al HOSNI, Mohammed, Al Kalbani, Moza, Al Riyami, Nihal, Al shaibi, Maha, Al-Mujaini, Abdullah, AlBusaidi, Hanadi, Alwashahi, Mohammed, Alzadjali, Adil, Dalmar, Khadija, Dawud, Bashar, Gargouri, Mohamed Mourad, Laghari, Farman Ali, Manjunatha, attibele Palaksha, Mathew, Joseph Kunju, Muzaffar, Rahil, Naiya, Hafsa Ismail Ibrahim, Pillai, Silja, Rahim, Ferdous, Stephen, Edwin, Younas, Shahzad, Fatima, Mishal, Javed, Ayesha, Shakir, Fatima Tuz Zahra, Siddiqui, Riaz Hussain, Sultan, Rizwan, Syed, Danish, Ur Rehman, Ishtiaq, Warraich, Shahrukh, Amir, Mohammed, Asghar, Saleha yurf, Haider Bangash, Ali, Ahmed, Arooj, Ansar, Mehwish, Arslan, Muhammad, Ashraf, Sumaira, Irshad, Abeer, Khan, Farheen, Shami, Dr Ali, Ul Haq, M Burhan, Waqar, Shahzad Hussain, Ahmed, Shahnoor, Ahsan, Kunwar Armash, Akhund, Ramsha, Chishti, Uzma, Haroon, Waqqas, Kassam, Nausheen, Kazmi, Abbas, Khan, Muhammad Osama, Kumari, Sameeta, Malik, Muhammad Jehangir, Mansoor, Maheen, Mubarik, Areeba, Naz, Falak, Qamar, Javeria Bilal, Sadia, Haleema, Safri, Mohammad, Sattar, abida K., Siddiqui, Muhammad Ahsan Iqbal, Waqar, Usama, Kerawala, Asad Ali, Ghufran, Muhammad Ali, Memon, Amjad Siraj, Rai, Lajpat, Samo, Khursheed Ahmed, Aswani, Manisha, Manzoor, Shahneela, Muhammad, Shoaib, Moin, Inshrah, Najjad, Muhammad Kazim Rahim, Zia, Kashif, Ali Shaikh, Shafqat, Ayub, Bushra, Hussaini, Dr, Kamal, Wajahat, Mughal, Zeeshan Uddin, Nadeem, Areeba, Nayyer, Fatima, Nisa, Kanwal, Rauf, Yaseen, Saleem, Shah Masabat, Sayyed, Raza, Shah, Aaqil, Siddiqui, Safia, Tariq, Nida, Zamir, Mehroz, Arif, Hafiz Muhammad, Ahmed, Ehsan, Ahmed, Jawad, Akbar, Bilal, Ali, Abrar Ashraf, Iqbal, Zafar, Jameel, Muhammad Khurram, Janjua, Muhammad Haris, Janjua, Azwa, Naqi, Syed Asghar, Naumeri, Fatima, Nazir, Umer, Rafi, Yaseen, Saleem, Irfan, Shaukat, Ayesha, Sikandar, Hafiz Saqib, Tu zahara, Fatima, Ali, Ahsan, Jawad, Muhammad, Noman, Hamza, Taha, Dr Hassan, Raana, Dr. Gul e, Qadir, Muhammad Ghulam, Ali, Imran, Asjad, Muhammad, Ayyaz, Mahmood, Bajwa, Luqman Ali, Bhatti, Samiullah, Butt, Usman, Chishti, Muhammad Haris, Hassan, Muhammad, Hassan, Usman, Hayat, Khizar, Khan, Rohma, Latif, Usman, Majeed, Faizan, Malik, Kiren, Nabi, Muhammad shoaib, Sadiq, Muhammad Hamza, Saeed, Komal, Sarfraz, Kiran, Sohail, Rubina, Syed muhammad, Bilal, Umair, Usama, Wasim, Shafqat, Wasim, Tayyiba, Imran Anwar, Muhammad, Ali, Ammar, Aslam, Muhammad, Sher e Murtaza, Muhammad, Farooq, Umer, Ahmad, Siddique, Faizi, Fouzia, Khan, Hamza, Mabood, Waleed, Akhtar, Muhammad Shaheer, Amin, Hasbi Allah, Ayub, Bakhtawar, Basir, Muhammad, Gul, Hina, Khan, Muhammad faisal, Moeen, Aiman, Mohmand, Obaid, Rahim, Rehana, Shafqat, Tanveer, Ur Rehman, Shams, Daud, Mashal, Abid, Rubaba, Farkhanda, Tallat, Malik, Sobia, Salim, Ruqyyah, Shaheen, Aneela, Ahmed, Faryal, Amjid, Zarafshan, Ishtiaq, Daniyal, Javed, Saad, Nagra, Ramisha Naseer, Saleem, Maleeha, Saleem, Bushra, Shabbir, Raja Khalid, Yaqoob, Eesha, Shaheen, Azka, Awad, Hadeel, Wafi, Dalia, Al-Slaibi, Ibrahim, I. A. Alzeerelhouseini, Hussam, Aljunaidi, Roaa, Amro, Adham, Shaheen, Farah, Shawer, Balqis, Shehadeh, Daleen, Demyati, Khaled, Rodriguez-Zentner, Homero, Aguilera Maidana, Domingo Javier, Bogarin, Amalia, Britez Barrios, Edulfo, Cespedes Ramirex, Luz Maria, Dragotto, Antonella, Fernandez, Celso Ariel, Gauto, Claudia, Gómez, Nadia, Karina, Liz, Martínez, Walter, Mora, Sergio, Noguera Roman, Lidia, Ocampos, Lorena, Ojeda Rojas, Alma Maria, Vera Florentin, Jorge David, Vömel, Jacob, Ferreira Aguilera, Maria Esther, Osorio, Derlis, Villanueva, Paulo, Centurion Rolon, Sandra Elizabeth, Ohara, Rozana, Portillo, Juan Marcelo, Varela Cano, Ruben Milciades, Candia, Francisco Vidal, Chirico, Carlos, Diaz Pineda, Sofia Belen, Paiva Vera, Diego Alfonso, Cantero, Daniel, Centurión, Jessica, Olmedo Bareiro, Ricardo Ignacio, Duarte, Dayhana, Delgado Godoy, Juan Marcelo, Segovia Lohse, Helmut Alfredo, Chavez Rivaldi, Cristhian, Martinez Velázquez, Maria Jose, Pedroso Alvarenga, Brayan David, Sánchez, Rosa, Segovia Lohse, Herald Rene, Falcon Pacheco, Glenda Marina, Flores Anaya, Estefany Angela, Huaman Huallanca, Evy Yamil, Marchan Palma, Karla Melissa, Paucar Urbina, Arazzelly Del Pilar, Ordemar, Jorge, Quiroz, Manuel, Rios Chiuyari, Jose, Lozano, Christian, Ormeño, Martin, Quispe-Cruz, Darwin Artidoro, Yamamoto Seto, Gaby Susana, Arias, Claudia, Silva Barandiaran, Jose Maria, Ugarte Oscco, Regina Amparo, Vergel Cabrera, Cesar Alberto, Mendiola, Gian, Salazar, Adolfo, Sánchez Estupiñan, Joel Jesús, Arangoytia, Roy, Bustamante Polo, Jorge Luis, Desposorio Armestar, Darwin Oliver, Lopez Blanco, Aldo, Moreno, Jaime, Cardenas, Daniel, Shiraishi Zapata, Carlos, Abella, Andrei Cesar, Bejasa, Monica Maria, Unira, Cristeta, Cajucom, Carlo Angelo, Ramos, Charmagne Loren, David, Avril, Merin, John Isaac, Candelario, Nipseey Pauloe, Lopez, Marc Paul, Violago, Khrissa Lea Elisa, Tesil, Mark Jheric, Almelor, Alyssa Carmina, Almora, Jaime Jr., Arbizo, Jeric, Barretto, Diana, de Grano, Pauleen, De Pano, Jojiemar, Delgado, Juan Miguel Roberto, Dulnuan, Heather Grace, Elises, Carlo, Hilvano-Cabungcal, Ana Melissa, Legaspi, Gerardo, Magsanoc, Nikko, Notario, Jaysonnel, Sacdalan, Marie Dione, Santos, Jan Armelynn, Sarmiento, Abigail, Serrano, Dennis, Siahetiong, Samantha, Valeros, Charmaine Grace, Venida, Vincent, Yap, Hans Edison, Estanislao, Grace Lynn, Ganal-Antonio, Anne Kathleen, Lim, Josephine Alexandra, Nazal, Mariles, Ong Vaño, Amanda May, Rivera, Ron Daniel, Salud, Jose Antonio, Uy, Avegail Niña, Dabalos, Jesus Jr, Yabut, Kenneth, Barcelon, Jose Carlos, Chiu, Jo Ann, Kotarski, Jan, Ferreira, Filipa, Gonçalves Nobre, José Guilherme, Henriques, Susana, Macedo, Alexandre, Mendes, Cláudia, Silva, Melissa, Ribeiro, Rui, Santos, Jos´é, Serralheiro, Pedro, B. 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Pereira, André, Pereira-Neves, António, Pina-Vaz, Teresa, Pinheiro, Gabriela, Pinho, Sílvia, Ramos, Pedro, Ramos, Patricia, Vilares Morgado, Rodrigo, Canotilho, Rita, Correia, Ana Margarida, Ferreira Pinto, Ana Paula, Claro, Mariana, Costa Santos, Daniel, Boto, Carlos, Branquinho, Rita, Rodrigues, Sónia, Guidi, Gonçalo, Leal, Clara, Machado, Luís, Marques, Prescillia, Martins, Daniela, Morais, Mariana, Nunes, Sara, Sapage, Rita, Sousa, Rita, Sousa, Diogo, Vaz Pereira, Ricardo, Lima Oliveira, Susana, Abdalla, Samir, Aurif, Fahad, Muzaffar, Nasir, Ahmed, Khalid, Al Dosouky, Mohammed, Al-Tarakji, Mohannad, Almudares, Saif, Elaffandi, Ahmed, Muslim, Muhammad, Qabbani, Amjad, Shah, Amjad, Khan, Mohammad Burhan, Murad, Musab, Costache, Victor, Dumitrescu, Tudor Ștefan, Muntean, George-Ovidiu, Mironescu, Aurel, Bezede, Cosmin, Enciu, Octavian, Baraian, Sergiu Catalin, Niculae, Cristina, Filipescu, Daniela, Goicea, Raluca, Alexe, Vlad, Batog, Olivia, Iliescu, Madalina, Ionescu, Sebastian, 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Rayzah, Musaed, Abd ElGhany, Reda, Al Ameer, Ahmed, Bawa, Dauda, Elzain, Mohammed, Wakill, Fadi, Fahiem-ul-Hassan, Mir, Al Duhileb, Mohammed, Alazzeh, Ghaleb, Alghazal, Thabet, Alkhatib, Abdulrahman, Almatar, Bikheet, Alnaimi, Manal, Alsuwaimel, Munir, Balhareth, Ameera, Abutaleb, Malak, Ageeli, Mohammed, Alhazmi, Barrag, Alkhayrat, Saud, Miftah, Mohammed, Otayfah, Sameer, Sari, AbdulRahman, Alsadiq, Mohammed, Fouad, Mohammed, Iskander, Othman, Al Athath, Samer, Alharthi, Mohammed, Bayazid, Muhannad, Al-Radi, Osman, Altaf, Abdulmalik, Arab, Fatima, Bangash, Mohammed, Basendowah, Mohammed, Farsi, Deema, Farsi, Ali, Habeebullah, Alaa, Malibary, Ziad, Nassif, Mohammed, Nawawi, Anfal, Sabbagh, Abdulrahman J, Sait, Salma, Saleem, Abdulaziz, Trabulsi, Nora, Alghamdi, Abdulaziz, Altalhi, Bassam, Alzaidi, Turki M, Mughal, Samiullah, Samadony, Mustafa, Althobaiti, Awwadh, Hakami, Hadi, Al Jamahir, Mohammed, Al Wadei, Hajr, Al-Qannass, Ali, Al-Qurashi, Qusay, Albakry, Ibrahim, Alkarak, Samer, 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Felwa, Almeshal, Meshal, Almohsen, Hadi, Almutairi, Hanan, Alomar, Osama, AlQahtani, Abdulmajeed, Alqarni, Saad, Alresaini, Fay, Alsakka, Musab, Alsemari, Muhannad, Alshahri, Jaffar, Alshanafey, Saud, AlShehri, Yasir, AlSumai, Thuraya, Altaher, Assma, Asiri, Ibrahim, Farrash, Faisal, Hassounah, Maher, Jarman, Abdulaziz, Maqbol, Sabreen, Mrad, Mohamed Amir, Othman, Eyas, Pant, Rajeev, Spangenberg, Peter, Tulbah, Maha, Ajomah, Nadia, Alghamdi, Rami, Almufarrih, Abdullah, Alsaloom, AlHanouf, Alsubaie, Norah, Siddiqui, Abu Talha, Ahmed, Kaleem, Ajlan, Abdulrazag, Alawi, Khalil, Alghuson, Lolowah, Alhalal, Hani, Alhassan, Basmah, Aljassir, Fawzi, Aljunaydil, Abdullah, Alkhamis, Waleed H., Almalki, Ahmad, Alowais, Jalal, Alsaleh, Nuha, Alsanawi, Hisham, Alyahya, Reem, Alzahrani, Meshari, Bassi, Ali, Mansour Alshammari, Nayef, Mortada, Hatan, Sabr, Yasser, Alajmi, Turki, Alrashed, Muath, Alsabahi, Tareq, Altahan, Talal, Altuwaijri, Mohammad, Alwabel, Muath, Alzahrani, Mosa, Al Faifi, Jubran, Alobaysi, Saad, Modahi, Nawaf, AI Nwijy, Khaled, AI Zahrani, Turki, Alahmad, Feras, Alalawi, Dr Yousef, Awaji, Ahmed, Emara, Sherif, Musawa, Nizar, Zakaria, Mahmoud, Althobaiti, Waleed, Paunovic, Ivan, Alajaji, Nouf, Ivanović, Nenad, Kmezić, Stefan, Knezevic, Djordje, Krivokapic, Zoran, Latinčić, Stojan, Markovic, Velimir, Miladinov, Marko, Ninic, Aleksandar, Gregoric, Pavle, Loncar, Zlatibor, Bogdanovic, Ivan, Milisavljević, Filip, Paunovic, Aleksandra, Trivic, Aleksandar, Bumbasirevic, Uros, Lazic, Aleksandar, Djurisic, Igor, Jevric, Marko, Kocic, Milan, Kozomara, Zoran, Markovic, Ivan, Dejanovic, Tatjana, Marinković, Srdjan, Milanovic, Miljan, Lazovic, Mikan, Cuk, Vladica, Milutinović, Vladan, Djan, Vladimir, Trajkovic, Velicko, Lukic, Dejan, Radovanovic, Zoran, Zahorjanski, Sanja, Hing, Jun Xian, Teo, Nan Zun, Arbab, Hana, Dimatatac, Doris Mae, Chew, Min Hoe, Tan, Kiat Tee Benita, Ang, Wei-Wen, Chong, Yew-Lam, Tan, Ming Ngan Aloysius, Wong, Kar Yong, Gális, Branislav, Avsenak, 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Miralpeix, Ester, Riba Combatti, Luisana, Sanz Llorente, Andrea, Bejarano Serrano, Miguel, Capdevila Vilaró, Blanca, Cuesta Argos, Mario, de Haro Jorge, Irene, García-Aparicio, Luis, Massaguer, Clara, Moraleda Gudayol, Ines, Muñoz Fernández, María Elena, Prat-Ortells, Jordi, Rojas-Ticona, Javier, Rubio-Palau, Josep, Nuñez, Jorge, Pascual, Montserrat, de la Torre, Javier, Alvarez Saez, Iago, Blanco-Colino, Ruth, Conesa, Anna, de Pablo García-Cuenca, Alba, Dediulia, Natalija, Espin-Basany, Eloy, Gil-Sala, Daniel, Guillén, Juan sebastian, Lopez, Manuel, Mateo Arzo, Maria Dolores, Montferrer Estruch, Nuria, Murillo, Judith, Perera Sarri, Remei, Porteiro Mariño, Lucia, Reche Padilla, Maria José, Rodriguez, Natalia, Rodríguez-Tesouro, Ana, Soler, Iñigo, Suescun López, Maria Carmen, Teixidor Serra, Jordi, Tormos Pérez, M Pilar, César, Vázquez García, González, Gloria, Medina Hernández, Mario Rafael, Pozo, Carolina, Valle, Antonio, Garcia De Cortazar, Unai, Villamor, Idoia, Landaluce-Olavarria, Aitor, Lecumberri, David, Martínez-Pinedo, Carlos, Morales-Puebla, José Manuel, Alcalá Rueda, Ignacio, Díaz Tapia, Gonzalo, Dieguez López, Maria, López García, Isabel, López-Toribio López, Pilar, Bosch, Marina, Fernández Candela, Alba, Lillo García, Cristina, Oller, Inmaculada, Sánchez-Guillén, Luis, Triguero Cánovas, Daniel, Aranda Lozano, Francisca, Del Pozo Andres, Eneko, Ochoa Villalabeitia, Begoña, Ortega, Natalia, Sanz Larrainzar, Amaia, Vicente Rodriguez, Irune, Jover, Jose M, Ramos Rodriguez, Jose Luis, Antonio, Codina, Delisau-Puig, Olga, Farrés Pla, Cristina, Maldonado-Marcos, Eloy, Tuca, Francesc, Guisado Calderón, Antonio Francisco, Pastor, Oscar, García Amador, Cristina, Allue, Marta, Colsa, Pablo, Ponchietti, Luca, Roldón Golet, Marta, Navarro-Sánchez, Antonio, Soto-Darias, Iván, Ortiz López, David, Berrocal, Sara, Cagigal Ortega, Elima Pilar, Díaz Peña, Patricia, Fernández Bernabé, Patricia, Fraga, Gema, García, Antonio, Garcia De Castro, Elena, García Domínguez, Antonio, Gonzalez, Judit, Ramos-Luengo, Adolfo, Busto Suarez, Sara, Castaño, Mario, De Arriba Alonso, Mario, Farrés Rabanal, Anna, Fernández-Samos Fernández, Diego, García Pérez, Cristina, Higuera Miguélez, Eva, Laguna, Gregorio, Perez, Irene, Alvarez Torres, Eva, Calderon Barajas, Zulay Adriana, Fernández, Aida, Jimenez-Roldan, Luis, Levstek, Meta, Parada Rodriguez, Ana Maria, Bonet, Mireya, Perez-Chrzanowska, Hanna, Serrano Méndez, Patricia, Jorgensen, Thomas W., Marquez, Lucila, Alonso Juarranz, Miguel, Ávila-Ramírez, Luis Felipe, Buendia Pérez, Javier, Burgos-Blasco, Barbara, Camarero Rodríguez, Enrique, Encinas Bascones, Alejandro, Fernandez-Martin, Elena, Gil Prados, Inés, Giraldo, Maria Alejandra, Gomez Cervantes, Manuel, Guemes Villahoz, Noemi, Iglesias Moreno, Maria Cruz, Leyva Rodríguez, Francisco, Poch, Adriana, Saez Carlin, Patricia, Sánchez del Pueblo, Cristina, González, Enrique, Caño Velasco, Jorge, Cuende Diez, Miguel, Polanco Pujol, Lucía, Ruiz 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Samrat, Wickramarachchi, Lilanthi, Yang, Yu Hsuen, Bitar, Samer, Chelva, Ruth, Gabr, Abdullah, Madni, Abdul, Mohamed, Musheer Hussain, Ramesh, Ashwanth, Ugam, Al-Tamimi, Yahia, Bacon, Andrew, Catto, James, Rominiyi, Ola, Tame, Oliver, Jackson, Richard, Kiely, John, Anjarwalla, Naffis, Kahka, Ehab, Patel, Arjun, Saeid, Sawsan, Samadi, Nilofar, Karar, Shoura, McCullough, Rebekah, Punnen, Aaron Julius, Danwaththa Liyanage, Aloka Suwanna, Aleem, Muhammad, Cathcart, Russell, Cohen, Olivia, Brinkler, Rebecca, Hayat, Zara, Parry, James, Adegbola, Samuel, Yeoh, Clarence, Melissa, Bromage, Stephen, Chatterji, Somashree, George, Suku, George, Smitha, Hunt, Janette, Kujawa, Magda, Munshi, Fatema, Rooney, Joanna, Zakieh, Imad, Zhang, Yuhao, Evans, Daisy, Sachdev, Bobby, Sadia, Uzma, Rajgor, Amarkumar D, Walters, Holt, Dube, Manas, Watson, Nicholas, Ananth, Sankar, Dhillon, Dharminder, Henry, Alastair, Lau, Godfrey, Li, Zoe, Shah, Ketan, Castelhano, Rute, Shah, Vinay, Win, Khine Myat, Davoudi, Kaveh, Foster, Paul, Hunt, Louise, Kamalakannan, Bhavani, Macdonald, Hamish, Morrison, Jo, Newitt, Laura, Parwaiz, Hammad, Slade, George, Stewart, Charles Geoffrey Dermot, Rhee, Jae, Sykes, Rosemary, Dickason, Aubrey, Ekpo, Ekemini, Scott, Rupert, de Rome, Katherine, Sahnan, Kapil, Ismayl, Ghiath, Moores, Thomas, Simmons, Mark, Techaboonanake, Sita, Abdelgalel, Khaled, Amin, Verda, Bhatnagar, Anuj, Charalampakis, Vasileios, Ramcharan, Sean, Galiveeti, Venkat mukund reddy, Massri, Erfan, Hassan, Abdulhakim, Lane, Oliver, McLellan, Morag, Shamim, Sarah, Vinayagam, Raman, Ross, Fiona, Blair, James, Dewan, Varun, Drew, William, Iftikhar, Zainab, Milner, Sean, Rajdev, Kishan, Reid, Jeremy, Thomas, Osmond, Adewusi, Mas’ud, Duckett, Abigail, El Falaha, Sara, Ooi, Chun, Mohamed Salim, Mohamed Ashiq, Ireson, Rebecca, MacDonald, Luisa, Ribeiro, Barbara, Savage, Alistair, Sharma, Tanisha, Swift, Paul, Elswick, Chase, Patel, Rakesh, Hemmila, Mark, Wong, Jane J, Amin, Dina, Chabuz, Carolyn, Gergen, Anna, Getz, Anne, Harmon, Laura, McIntyre, Robert, Meguid, Robert, Rodriguez, Kenny, Scott, Christopher, Steward, Lauren, Stewart, Camille, Thieu, Daniel, Velopulos, Catherine, Vogel, Jon, Bengtson, Erika, Hill, Charles, Holan, Cole, Kay, Hannah, McElhinney, Kathryn, Osterberg, E. Charles, Rossano, Ayane, Trust, Marc, Bigelow, Benjamin, Jain, Amit, Yesantharao, Lekha, Zhang, Bo, Abdou, Hossam, Mazzeffi, Michael, Rock, Peter, Afshar, Salim, Carlson, Laura, Incorvia, Joseph, Kurtz, Michael, Meara, John G., Nathan, Meena, Taghinia, Amir, Williams, Vivian, Cooper, Zara, Mahvi, David, Okafor, Barbara, Roxo, Vanessa, Burks, Ciersten, Jabbour, Nicolette, Sabra, Joseph, Wason, Shaun, Dorken Gallastegi, Ander, Gebran, Anthony, McTague, Michael, Reinke, Caroline, Ross, Samuel, Alvarado, Rosalinda, Bhama, Anuradha, Govekar, Henry, Kokosis, George, Millikan, Keith, Myers, Jonathan, Pappas, Sam, Siparsky, Nicole, Tsambarlis, Peter, Quillin, Ralph, Ekrami, Elyad, Kai, Li, Decker, Cassie, Aoun, Salah, Kwon, David, Barbas, Andrew, Dotters-Katz, Sarah K., Ellett, Tressa, Flamant, Etienne, Lazarides, Alexander, Refaat, Motasem, Soderlund, Torre, Velasquez, Camilo, Arrangoiz, Rodrigo, Mijares Olivo, Maria Fernanda, Vasudevan, Vanitha, Katz, Matthew, Nguyen, Huan, Pieretti, Alberto, Roland, Christina L, Baral, Perel, Beahm, D. David, Carver, Shea, Guidry, Christopher A., Hedlund, Megan, Kumer, Sean, Larson, Kelsey E, Urich, Alissa, Rosenkranz, Kari, Bhavaraju, Avi, Kalkwarf, Kyle, Hua-Feng, Lien, Juillard, Catherine, Tillou, Areti, Mouw, Tyler, Dunn, Julie, Wyatt, Thomas, Aiken, Taylor, Foley, Eugene, Zafar, Syed Nabeel, Lewit, Ruth A., Cioci, Alessia, Goel, Neha, Kronenfeld, Joshua, Rattan, Rishi, LaRocca, Christopher J., Ramaswamy, Archana, Mattson, Jordan, Vogel, Rachel, Bethurum, Alva, Bhalla, Rohan, Bichell, David, Bonfield, Christopher, Dewan, Michael, Ghani, Muhammad Owais Abdul, Hawkins, Alexander, Khan, Aimal, Kynes, J. Matthew, Ruzgar, Nensi Melissa, Alqunaibit, Dalia, Liveris, Anna, McNelis, John, Goldstein, Carma, Nguyen, Anh, Rattigan, Deviney, Solar, Sara, Tsui, Grace, Gaitanidis, Apostolos, Fitzmaurice, Laura, Jutric, Zeljka, Tay Lasso, Erika Linmey, Yamamoto, Maki, Meola, Antonio, Holena, Daniel, Imran, Jonathan, Lorenzi, Cara, Huckaby, Lauren, Hamandi, Mohanad, Lanfear, Allison T., Squiers, John, Behm, Kevin, Boughey, Judy, Reisenauer, Janani, Shawki, Sherief, Wigle, Dennis, Elshabrawy, Ahmed, Mansour, Ahmed, Todd, Grace Ihsiu, Yan, Qi, Curry, Terry, Abel, Mary Kathryn, Andaya, Veronica, Boeck, Marissa, Chen, Lee-may, Compadre, Amanda, Ha, Patrick, Kratz, Johannes R, Lane, Rondall, Lee, Rex H, Ozgediz, Doruk, Varma, Madhulika, Zimel, Melissa, Escobar, Pedro, Azam, Mohammad, Hammond, Eric, Marx, William, Angel, Carol, Seegert, Sara, Stanek, Stephen, Sumra, Hibba, Fischer, Anne, Henry, Jaymie, Lottenberg, Lawrence, Kelly, John, Scott, Erin, Bonilla Cal, Fernando, Haro, Camila, Álvarez, Sofia, 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Hardy, A, Khojani, M, Mazurek, J, Raymond, T, Reddy, V, Reynolds, J, Soma, A, Agiotakis, S, Alsusa, H, Desai, N, Peristerakis, I, Adcock, A, Ayub, H, Bennett, T, Bibi, F, Brenac, S, Chapman, T, Clarke, G, Clark, F, Galvin, C, Gwyn-Jones, A, Henry-Blake, C, Kerner, S, Kiandee, M, Lovett, A, Pilecka, A, Ravindran, R, Siddique, H, Sikand, T, Treadwell, K, Akmal, K, Apata, A, Barton, O, Broad, G, Darling, H, Dhuga, Y, Emms, L, Habib, S, Jain, R, Jeater, J, Kan, CYP, Kathiravelupillai, A, Khatkar, H, Kirmani, S, Kulasabanathan, K, Lacey, H, Lal, K, Manafa, C, Mansoor, M, McDonald, S, Mittal, A, Mustoe, S, Nottrodt, L, Oliver, P, Papapetrou, I, Pattinson, F, Raja, M, Reyhani, H, Shahmiri, A, Small, O, Soni, U, Aguirrezabala Armbruster, B, Bunni, J, Hakim, MA, Hawkins-Hooker, L, Howell, KA, Hullait, R, Jaskowska, A, Ottewell, L, Thomas-Jones, I, Vasudev, A, Clements, B, Fenton, J, Gill, M, Haider, S, Lim, AJM, Maguire, H, McMullan, J, Nicoletti, J, Samuel, S, Unais, MA, White, N, Yao, PC, Yow, L, Boyle, C, Brady, R, Cheekoty, P, Cheong, J, Chew, SJHL, Chow, R, Ganewatta Kankanamge, D, Mamer, L, Mohammed, B, Ng Chieng Hin, J, Renji Chungath, R, Royston, A, Sharrad, E, Sinclair, R, Tingle, S, Treherne, K, Wyatt, F, Maniarasu, VS, Moug, S, Appanna, T, Bucknall, T, Hussain, F, Owen, A, Parry, M, Parry, R, Sagua, N, Spofforth, K, Yuen, ECT, Bosley, N, Hardie, W, Moore, T, Regas, C, Abdel-Khaleq, S, Ali, N, Bashiti, H, Buxton-Hopley, R, Constantinides, M, D’Afflitto, M, Deshpande, A, Duque Golding, J, Frisira, E, Germani Batacchi, M, Gomaa, A, Hay, D, Hutchison, R, Iakovou, A, Iakovou, D, Ismail, E, Jefferson, S, Jones, L, Khouli, Y, Knowles, C, Mason, J, McCaughan, R, Moffatt, J, Morawala, A, Nadir, H, Neyroud, F, Nikookam, Y, Parmar, A, Pinto, L, Ramamoorthy, R, Richards, E, Thomson, S, Trainer, C, Valetopoulou, A, Vassiliou, A, Wantman, A, Wilde, S, Dickinson, M, Rockall, T, Senn, D, Wcislo, K, Zalmay, P, Adelekan, K, Allen, K, Bajaj, M, Gatumbu, P, Hang, S, Hashmi, Y, Kaur, T, Kawesha, A, Kisiel, A, Woodmass, M, Adelowo, T, Ahari, D, Alhwaishel, K, Atherton, R, Clayton, B, Cockroft, A, Curtis Lopez, C, Hilton, M, Ismail, N, Kouadria, M, Lee, L, MacConnachie, A, Monks, F, Mungroo, S, Nikoletopoulou, C, Pearce, L, Sara, X, Shahid, A, Suresh, G, Wilcha, R, Atiyah, A, Davies, E, Dermanis, A, Gibbons, H, Hyde, A, Lawson, A, Lee, C, Leung-Tack, M, Li Saw Hee, J, Mostafa, O, Nair, D, Pattani, N, Plumbley-Jones, J, Pufal, K, Ramesh, P, Sanghera, J, Saram, S, Scadding, S, See, S, Stringer, H, Torrance, A, Vardon, H, Wyn-Griffiths, F, Brew, A, Kaur, G, Soni, D, Tickle, A, Akbar, Z, Appleyard, T, Figg, K, Jayawardena, P, Johnson, A, Kamran Siddiqui, Z, Lacy-Colson, J, Oatham, R, Rowlands, B, Sludden, E, Turnbull, C, Allin, D, Ansar, Z, Azeez, Z, Dale, VH, Garg, J, Horner, A, Jones, S, Knight, S, McGregor, C, McKenna, J, McLelland, T, Packham-Smith, A, Rowsell, K, Spector-Hill, I, Adeniken, E, Baker, J, Bartlett, M, Chikomba, L, Connell, B, Deekonda, P, Dhar, M, Elmansouri, A, Gamage, K, Goodhew, R, Hanna, P, Knight, J, Luca, A, Maasoumi, N, Mahamoud, F, Manji, S, Marwaha, PK, Mason, F, Oluboyede, A, Pigott, L, Razaq, AM, Richardson, M, Saddaoui, I, Wijeyendram, P, Yau, S, Atkins, W, Liang, K, Miles, N, Praveen, B, Ashai, S, Braganza, J, Common, J, Cundy, A, Davies, R, Guthrie, J, Handa, I, Iqbal, M, Ismail, R, Jones, C, Jones, I, Lee, KS, Levene, A, Okocha, M, Olivier, J, Smith, A, Subramaniam, E, Tandle, S, Wang, A, Watson, A, Wilson, C, Chan, XHF, Khoo, E, Montgomery, C, Norris, M, Pugalenthi, PP, Common, T, Cook, E, Mistry, H, Shinmar, HS, Agarwal, G, Bandyopadhyay, S, Brazier, B, Carroll, L, Goede, A, Harbourne, A, Lakhani, A, Lami, M, Larwood, J, Martin, J, Merchant, J, Pattenden, S, Pradhan, A, Raafat, N, Rothwell, E, Shammoon, Y, Sudarshan, R, Vickers, E, Wingfield, L, Ashworth, I, Azizi, S, Bhate, R, Chowdhury, T, Christou, A, Davies, L, Dwaraknath, M, Farah, Y, Garner, J, Gureviciute, E, Hart, E, Jain, A, Javid, S, Kankam, HK, Kaur Toor, P, Kaz, R, Kermali, M, Khan, I, Mattson, A, McManus, A, Murphy, M, Nair, K, Ngemoh, D, Norton, E, Olabiran, A, Parry, L, Payne, T, Pillai, K, Price, S, Punjabi, K, Raghunathan, A, Ramwell, A, Raza, M, Ritehnia, J, Simpson, G, Smith, W, Sodeinde, S, Studd, L, Subramaniam, M, Thomas, J, Towey, S, Tsang, E, Tuteja, D, Vasani, J, Vio, M, Badran, A, Adams, J, Anthony Wilkinson, J, Asvandi, S, Austin, T, Bald, A, Bix, E, Carrick, M, Chander, B, Chowdhury, S, Cooper Drake, B, Crosbie, S, D Portela, S, Francis, D, Gallagher, C, Gillespie, R, Gravett, H, Gupta, P, Ilyas, C, James, G, Johny, J, Jones, A, Kinder, F, MacLeod, C, Macrow, C, Maqsood-Shah, A, Mather, J, McCann, L, McMahon, R, Mitham, E, Mohamed, M, Munton, E, Nightingale, K, O‚ÄôNeill, K, Onyemuchara, I, Senior, R, Shanahan, A, Sherlock, J, Spyridoulias, A, Stavrou, C, Stokes, D, Tamang, R, Taylor, E, Trafford, C, Uden, C, Waddington, C, Yassin, D, Zaman, M, Bangi, S, Cheng, T, Chew, D, Hussain, N, Imani-Masouleh, S, Mahasivam, G, McKnight, G, Ng, HL, Ota, HC, Pasha, T, Ravindran, W, Shah, K, Vishnu K, S, Zaman, S, Carr, W, Cope, S, Eagles, EJ, Howarth-Maddison, M, Li, CY, Reed, J, Ridge, A, Stubbs, T, Teasdaled, D, Umar, R, Worthington, J, Dhebri, A, Kalenderov, R, Alattas, A, Arain, Z, Bhudia, R, Chia, D, Daniel, S, Dar, T, Garland, H, Girish, M, Hampson, A, Kyriacou, H, Lehovsky, K, Mullins, W, Omorphos, N, Vasdev, N, Venkatesh, A, Waldock, W, Bhandari, A, Brown, G, Choa, G, Eichenauer, CE, Ezennia, K, Kidwai, Z, Lloyd-Thomas, A, Macaskill Stewart, A, Massardi, C, Sinclair, E, Skajaa, N, Smith, M, Tan, I, Afsheen, N, Anuar, A, Azam, Z, Bhatia, P, Davies-kelly, N, Dickinson, S, Elkawafi, M, Ganapathy, M, Gupta, S, Khoury, EG, Licudi, D, Mehta, V, Neequaye, S, Nita, G, Tay, VL, Zhao, S, Botsa, E, Cuthbert, H, Elliott, J, Furlepa, M, Lehmann, J, Mangtani, A, Narayan, A, Nazarian, S, Parmar, C, Shah, D, Shaw, C, Zhao, Z, Beck, C, Caldwell, S, Clements, JM, French, B, Kenny, R, Kirk, S, Lindsay, J, McClung, A, McLaughlin, N, Watson, S, Whiteside, E, Alyacoubi, S, Arumugam, V, Beg, R, Dawas, K, Garg, S, Lloyd, ER, Mahfouz, Y, Manobharath, N, Moonesinghe, R, Morka, N, Patel, K, Prashar, J, Yip, S, Adeeko, ES, Ajekigbe, F, Bhat, A, Evans, C, Farrugia, A, Gurung, C, Long, T, Malik, B, Manirajan, S, Newport, D, Rayer, J, Ridha, A, Ross, E, Saran, T, Sinker, A, Waruingi, D, Allen, R, Al Sadek, Y, Alves do Canto Brum, H, Asharaf, H, Ashman, M, Balakumar, V, Barrington, J, Baskaran, R, Berry, A, Bhachoo, H, Bilal, A, Boaden, L, Chia, WL, Covell, G, Crook, D, Dadnam, F, Davis, L, De Berker, H, Doyle, C, Fox, C, Gruffydd-Davies, M, Hafouda, Y, Hill, A, Hubbard, E, Hunter, A, Inpadhas, V, Jamshaid, M, Jandu, G, Jeyanthi, M, Jones, T, Kantor, C, Kwak, SY, Malik, N, Matt, R, McNulty, P, Miles, C, Mohomed, A, Myat, P, Niharika, J, Nixon, A, O‚ÄôReilly, D, Parmar, K, Pengelly, S, Price, L, Ramsden, M, Turnor, R, Wales, E, Waring, H, Wu, M, Yang, T, Ye, TTS, Zander, A, Zeicu, C, Bellam, S, Francombe, J, Kawamoto, N, Rahman, MR, Sathyanarayana, A, Tang, HT, Cheung, J, Hollingshead, J, Page, V, Sugarman, J, Wong, E, Chiong, J, Fung, E, Kan, SY, Kiang, J, Kok, J, Krahelski, O, Liew, MY, Lyell, B, Sharif, Z, Speake, D, Alim, L, Amakye, NY, Chandrasekaran, J, Chandratreya, N, Drake, J, Owoso, T, Thu, YM, Abou El Ela Bourquin, B, Alberts, J, Chapman, D, Rehnnuma, N, Ainsworth, K, Carpenter, H, Emmanuel, T, Fisher, T, Gabrel, M, Guan, Z, Hollows, S, Hotouras, A, Ip Fung Chun, N, Jaffer, S, Kallikas, G, Kennedy, N, Lewinsohn, B, Liu, FY, Mohammed, S, Rutherfurd, A, Situ, T, Stammer, A, Taylor, F, Thin, N, Urgesi, E, Zhang, N, Ahmad, MA, Bishop, A, Bowes, A, Dixit, A, Glasson, R, Hatta, S, Hatt, K, Larcombe, S, Preece, J, Riordan, E, Fegredo, D, Haq, MZ, Li, C, McCann, G, Stewart, D, Baraza, W, Bhullar, D, Burt, G, Coyle, J, Deans, J, Devine, A, Hird, R, Ikotun, O, Manchip, G, Ross, C, Storey, L, Tan, WWL, Tse, C, Warner, C, Whitehead, M, Wu, F, Court, EL, Crisp, E, Huttman, M, Mayes, F, Robertson, H, Rosen, H, Sandberg, C, Smith, H, Al Bakry, M, Ashwell, W, Bajaj, S, Bandyopadhyay, D, Browlee, O, Burway, S, Chand, CP, Elsayeh, K, Elsharkawi, A, Evans, E, Ferrin, S, Fort-Schaale, A, Iacob, M, I, K, Impelliziere Licastro, G, Mankoo, AS, Olaniyan, T, Otun, J, Pereira, R, Reddy, R, Saeed, D, Simmonds, O, Singhal, G, Tron, K, Wickstone, C, Williams, R, Bradshaw, E, De Kock Jewell, V, Houlden, C, Knight, C, Metezai, H, Mirza-Davies, A, Seymour, Z, Spink, D, and Wischhusen, S
- Abstract
Pulmonary complications are the most common cause of death after surgery. This study aimed to derive and externally validate a novel prognostic model that can be used before elective surgery to estimate the risk of postoperative pulmonary complications and to support resource allocation and prioritisation during pandemic recovery.
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- 2024
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4. A nationwide cross-sectional study investigating adherence to the Mediterranean diet, smoking, alcohol and work habits, hormonal dynamics between breast cancer cases and healthy subjects
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Conte, Luana, Lupo, Roberto, Lezzi, Alessia, Paolo, Vitandrea, Rubbi, Ivan, Rizzo, Emanuele, Carvello, Maicol, Calabrò, Antonino, Botti, Stefano, De Matteis, Elisabetta, Massafra, Raffaella, Vitale, Elsa, and De Nunzio, Giorgio
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Despite substantial efforts in promoting prevention and the advancements in surgical and minimally invasive techniques, breast cancer remains a leading cause of mortality among women worldwide. Genetics and risk factors, including diet and lifestyle, play a critical role in determining the susceptibility to this neoplasm. The primary objective of this study is to investigate the pivotal role of adherence to the Mediterranean diet in breast cancer prevention. Additionally, we assessed differences in diet, Body Mass Index (BMI), smoking and alcohol habits, work shifts, exposure to environmental pollutants, and hormonal factors between patients with previously diagnosed breast cancer and healthy subjects.
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- 2024
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5. FINANCIAL INCLUSION AND THE 'WAR FOR CASH'.
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Lupo-Pasini, Federico
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Financial inclusion -- Models -- Research ,Cash transactions -- Demographic aspects -- Social aspects -- Usage ,Electronic funds transfer systems -- Demographic aspects -- Social aspects -- Usage - Abstract
I INTRODUCTION When digital payments took the fight for financial inclusion to a new level, cash was seen by many as its most prominent victim--a relic of a not so [...]
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- 2021
6. Association between specialist compensation and Accountable Care Organization performance
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Ganguli, Ishani, Lupo, Claire, Mainor, Alexander J., Orav, Endel John, Blanchfield, Bonnie B., Lewis, Valerie A., and Colla, Carrie H.
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Medicare -- Evaluation ,Medical fees -- Management -- Evaluation -- Influence ,Health services administration -- Evaluation ,Company business management ,Business ,Health care industry - Abstract
Objective: To determine if Medicare Shared Savings Program Accountable Care Organizations (ACOs) using cost reduction measures in specialist compensation demonstrated better performance. Data Sources: National, cross-sectional survey data on ACOs (2013-2015) linked to public-use data on ACO performance (2014-2016). Study Design: We compared characteristics of ACOs that did and did not report use of cost reduction measures in specialist compensation and determined the association between using this approach and ACO savings, outpatient spending, and specialist visit rates. Principal Findings: Of 160 ACOs surveyed, 26 percent reported using cost reduction measures to help determine specialist compensation. ACOs using cost reduction in specialist compensation were more often physician-led (68.3 vs 49.6 percent) and served higher-risk patients (mean Hierarchical Condition Category score 1.09 vs 1.05). These ACOs had similar savings per beneficiary year (adjusted difference $82.6 [95% CI -77.9, 243.1]), outpatient spending per beneficiary year (-24.0 [95% CI -248.9, 200.8]), and specialist visits per 1000 beneficiary years (369.7 [95% CI -9.3, 748.7]). Conclusion: Incentivizing specialists on cost reduction was not associated with ACO savings in the short term. Further work is needed to determine the most effective approach to engage specialists in ACO efforts. KEYWORDS Accountable Care Organizations, cost reduction, specialists, value-based payment, 1 | INTRODUCTION Accountable Care Organizations (ACOs) are provider groups that coordinate to provide high-quality care within a spending target for a defined patient population. While ACO leaders have focused [...]
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- 2020
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7. A New Step-Up Dual Endoscopic Approach for Large-Size Infected Pancreatic Necrosis: Percutaneous Endoscopic Necrosectomy Followed by Transluminal Endoscopic Drainage/Necrosectomy
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Mangiafico, Santi, Bertani, Helga, Pigò, Flavia, Russo, Salvatore, Lupo, Marinella, Cocca, Silvia, Grande, Giuseppe, Germani, Ugo, Manta, Raffaele, and Conigliaro, Rita
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- 2024
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8. La Sindrome Insulinica Autoimmune (Sindrome di Hirata): dalla clinica al trattamento
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Verrienti, Martina, Daniele, Andrea, Lupo, Sabrina, Franceschetti, Paola, Zatelli, Maria Chiara, and Ambrosio, Maria Rosaria
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La Sindrome di Hirata è una forma rara di ipoglicemia iperinsulinemica endogena, caratterizzata da elevati livelli di autoanticorpi anti-insulina. La patogenesi prevede una combinazione tra predisposizione genetica ed elementi trigger (farmaci, virus); alcune forme sono idiopatiche. Non sono disponibili indicazioni terapeutiche codificate a causa della rarità della condizione. La dieta ultra-frazionata a basso contenuto di carboidrati, l’uso di immunosoppressori e la plasmaferesi possono essere considerati per favorire il controllo dei sintomi.
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- 2024
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9. CTX-M-15/27-positive Escherichia coliand VIM-2-producing Pseudomonas putidain free-living pigeons (Columba livia) in Tunisia
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Souguir, Meriem, Châtre, Pierre, Drapeau, Antoine, Azaiez, Sana, Hmidi, Imen, Ncir, Sana, Lupo, Agnese, Madec, Jean-Yves, Haenni, Marisa, and Mansour, Wejdene
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•About 5.8% (12/206) of the pigeons carried an ESBL-producing Enterobacterale isolate.•Two pigeons carried a VIM-2-producing Pseudomonas putidaisolate.•Plasmidic transmission of the IncF/F-:A-:B53 plasmid was observed.•Clonal spread of the Escherichia coliST5584 and ST8149 was observed between two farms.
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- 2024
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10. Axon guidance cue SEMA3A promotes the aggressive phenotype of basal-like PDAC
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Lupo, Francesca, Pezzini, Francesco, Pasini, Davide, Fiorini, Elena, Adamo, Annalisa, Veghini, Lisa, Bevere, Michele, Frusteri, Cristina, Delfino, Pietro, D'agosto, Sabrina, Andreani, Silvia, Piro, Geny, Malinova, Antonia, Wang, Tian, De Sanctis, Francesco, Lawlor, Rita Teresa, Hwang, Chang-il, Carbone, Carmine, Amelio, Ivano, Bailey, Peter, Bronte, Vincenzo, Tuveson, David, Scarpa, Aldo, Ugel, Stefano, and Corbo, Vincenzo
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ObjectiveThe dysregulation of the axon guidance pathway is common in pancreatic ductal adenocarcinoma (PDAC), yet our understanding of its biological relevance is limited. Here, we investigated the functional role of the axon guidance cue SEMA3A in supporting PDAC progression.DesignWe integrated bulk and single-cell transcriptomic datasets of human PDAC with in situ hybridisation analyses of patients’ tissues to evaluate SEMA3A expression in molecular subtypes of PDAC. Gain and loss of function experiments in PDAC cell lines and organoids were performed to dissect how SEMA3A contributes to define a biologically aggressive phenotype.ResultsIn PDAC tissues, SEMA3A is expressed by stromal elements and selectively enriched in basal-like/squamous epithelial cells. Accordingly, expression of SEMA3A in PDAC cells is induced by both cell-intrinsic and cell-extrinsic determinants of the basal-like phenotype. In vitro, SEMA3A promotes cell migration as well as anoikis resistance. At the molecular level, these phenotypes are associated with increased focal adhesion kinase signalling through canonical SEMA3A-NRP1 axis. SEMA3A provides mouse PDAC cells with greater metastatic competence and favours intratumoural infiltration of tumour-associated macrophages and reduced density of T cells. Mechanistically, SEMA3A functions as chemoattractant for macrophages and skews their polarisation towards an M2-like phenotype. In SEMA3Ahightumours, depletion of macrophages results in greater intratumour infiltration by CD8+T cells and better control of the disease from antitumour treatment.ConclusionsHere, we show that SEMA3A is a stress-sensitive locus that promotes the malignant phenotype of basal-like PDAC through both cell-intrinsic and cell-extrinsic mechanisms.
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- 2024
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11. Racial, Ethnic, and Socioeconomic Disparities in COVID-19 Pandemic Worries
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Hoven, Christina W., Krasnova, Anna, Bresnahan, Michaeline, Sun, Xiaoxiao, Musa, George, Geronazzo-Alman, Lupo, Ryan, Megan, Skokauskas, Norbert, Amsel, Lawrence, Svob, Connie, Goodwin, Renee D., Zemeck, Heather, and Cheslack-Postava, Keely
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Background: Racial, ethnic, and socioeconomic health disparities became evident during the COVID-19 pandemic. This study explores whether these disparities extend to the content of worries. Methods: We surveyed 1,222 participants from three metropolitan New York City (NYC) based cohorts through telephone interviews conducted from March to September 2020. Worries were assessed using 37 dichotomous questionnaire items, and exploratory factor analysis derived ten categories of worry. Factor scores were analyzed in generalized linear mixed models to examine their associations with race/ethnicity and household income, adjusting for covariates. Results: The most prevalent worry items pertained to U.S. and world politics, American values, health concerns, and return to normalcy. Higher household income was associated with lower worry about economic needs, job/employment, and violence/victimization, while violence/victimization worries were strongly associated with Asian, Hispanic, Black, and multiracial or other race/ethnicity. Conclusions: During early COVID-19, lower-income and minoritized race and ethnic groups were disproportionately affected by economic and violence/victimization worries, while other worries showed minor variations by income or race/ethnicity.
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- 2024
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12. Trial Readiness of Cavernous Malformations With Symptomatic Hemorrhage, Part I: Event Rates and Clinical Outcome
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Flemming, Kelly D., Kim, Helen, Hage, Stephanie, Mandrekar, Jay, Kinkade, Serena, Girard, Romuald, Torbey, Michel, Huang, Judy, Huston, John, Shu, Yunhong, Lanzino, Giuseppe, Selwyn, Reed, Hart, Blaine, Mabray, Marc, Feghali, James, Sair, Haris I., Narvid, Jared, Lupo, Janine M., Lee, Justine, Stadnik, Agnieszka, Alcazar-Felix, Roberto J., Shenkar, Robert, Lane, Karen, McBee, Nichole, Treine, Kevin, Ostapkovich, Noeleen, Wang, Ying, Thompson, Richard, Koenig, James I., Carroll, Timothy, Hanley, Daniel, and Awad, Issam
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- 2024
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13. Trial Readiness of Cavernous Malformations With Symptomatic Hemorrhage, Part II: Biomarkers and Trial Modeling
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Hage, Stephanie, Kinkade, Serena, Girard, Romuald, Flemming, Kelly D., Kim, Helen, Torbey, Michel T., Huang, Judy, Huston, John, Shu, Yunhong, Selwyn, Reed G., Hart, Blaine L., Mabray, Marc C., Feghali, James, Sair, Haris I., Narvid, Jared, Lupo, Janine M., Lee, Justine, Stadnik, Agnieszka, Alcazar-Felix, Roberto J., Shenkar, Robert, Hobson, Nicholas, DeBiasse, Dorothy, Lane, Karen, McBee, Nichole A., Treine, Kevin, Ostapkovich, Noeleen, Wang, Ying, Thompson, Richard E., Koenig, James I., Carroll, Timothy, Hanley, Daniel F., and Awad, Issam A.
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- 2024
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14. Fast Digital Phase Detection of a Coherent Tone At GHz Frequencies
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Palma, L. Di, Mastrovito, P., Miano, A., Salim, A. J., Lupo, F.V., Bernhardt, J., Di Marino, L., Massarotti, D., Pepe, G. P., Tafuri, F., Mukhanov, O. A., and Arzeo, M.
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We present a detection technique based on a flux-switchable Josephson Digital Phase Detector (JDPD), which is capable of discriminating between two phase values of a coherent input tone. When suitably flux stimulated, the JDPD switches from a single-minimum to a double-minima potential and, as a result, relaxes in one of two stable configurations depending on the phase sign of the input stimulus. The outcome of this procedure is digitally encoded in the occupation probability of the phase particle in either of the two JDPD wells. In this manuscript, we demonstrate the working principle of the JDPD by discriminating the phase of a 5 GHz tone with a protocol of 300 ns of time duration. This result supports the future implementation of the JDPD to readout the state of a qubit.
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- 2024
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15. Digital Logic Based on Superconducting Gate-Controlled Transistors
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Lupo, Federico Vittorio, Margineda, Daniel, Puglia, Claudio, De Simoni, Giorgio, Macaluso, Roberto, Giazotto, Francesco, Mukhanov, Oleg A., and Arzeo, Marco
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A novel superconducting device based on voltage-controlled critical current suppression has been demonstrated, with the capability of being employed as a superconducting three-terminal gate-assisted transistor: the EF-Tron. In this work, we explore the potential of the EF-Tron for building superconducting logic elements. We have developed a continuous Verilog-A model and performed SPICE simulations of different logical circuits, including examples of combinatorial, sequential circuits, and ring oscillator. The simulation results will provide guidance for device design, manufacturing, and experimental testing. The obtained results and developed circuits can be used as logical building blocks for an Arithmetic-Logic Unit (ALU) and further scaled to more complex digital designs.
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- 2024
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16. A mixed-methods investigation of third and sixth graders’ academic sentence knowledge
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Townsend, Dianna, Knecht, Rachel, Lupo, Sarah, Chen, Li-Ting, and Barrios, Vickie Smith
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This qualitative-dominant mixed methods study aimed to investigate how native English speaking third graders (n= 72) and sixth graders (n= 88) navigate cohesive ties in academic sentences. There are studies on supporting students with academic language at the word and text levels, but less research has been done on readers’ knowledge of the dense and challenging sentences in academic texts. The current study examines both how students navigate cohesion in academic sentences as well as how their knowledge of cohesion relates to their performance on reading comprehension measures. With a multi-case study framework, we analyzed students’ (n= 6) metalinguistic interviews with academic sentences. We then designed Maze tasks for a larger sample (n= 160) to identify patterns in students’ knowledge of cohesion. We also conducted correlational analyses between students’ sentence-level knowledge and performance on measures of reading comprehension. Qualitative findings suggest that students draw on both metalinguistic and epilinguistic knowledge to explain cohesion, and that students value explicit instruction with academic sentences. Quantitative findings show that knowledge of cohesive ties is significantly correlated with performance on reading comprehension measures. Implications and future research for both monolingual and multilingual learners are addressed.
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- 2023
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17. Social reproduction, women’s labour and systems of life: A conversation
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Fernandes, Marianna, Lupo, Luisa, Benya, Asanda, Dedeoğlu, Saniye, Mezzadri, Alessandra, and Prügl, Elisabeth
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This conversation brings together feminist scholars from various backgrounds and epistemological traditions around a central topic in feminist debates that is today more relevant than ever, social reproduction. It begins by examining social reproduction as a concept and its entanglements with the dynamics of global capitalism from human geography and feminist international political economy perspectives. We ask, what does the lens of social reproduction bring to light? We discuss how social reproduction is a fundamentally political concept that bridges classic labour struggles with demands around housing, service provision and the reproduction of life in general. As a concept, it makes visible the systems of life that support the labour process, both daily and intergenerationally, in sites of production along global supply chains, from the garment industry, to mining and agriculture. Nevertheless, there is a need to consider how gendered dichotomies of productive and reproductive that underpin its modern origin may or may not undermine this concept and to rethink how, ultimately, we organise around social reproductive struggles. The conversation took place in June 2022 and has been edited for clarity.
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- 2023
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18. Oncogenèse pulmonaire et bases biologiques des traitements ciblés
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Blons, H., Lupo-Mansuet, A., Garinet, S., Wislez, M., Mascaux, C., Levallet, G., and Leroy, K.
- Abstract
Comme pour tout cancer, les lésions tumorales pulmonaires résultent de l’acquisition d’un ensemble de mutations dites « driver » (pilote), associées à des modifications épigénétiques et à la mise en place d’un micro-environnement tumoral stromal, vasculaire et immunitaire permissif. Les mécanismes à l’origine de l’oncogenèse pulmonaire ont été largement étudiés et leur compréhension a bénéficié des études génomiques récentes, comme celles de la cohorte TRACERx. Certaines mutations sont associées à une dépendance oncogénique pouvant être spécifiquement ciblée. L’évolution clonale et sous-clonale des cellules tumorales conditionne l’histoire naturelle de la maladie, la survenue de récidives ou métastases à distance, l’apparition de résistance aux traitements, et notamment aux thérapies ciblées. Dans cette revue, nous nous focaliserons sur les processus touchant les cellules tumorales et nous n’aborderons pas les aspects liés au micro-environnement tumoral, même si celui-ci joue un rôle essentiel dans la survenue et l’évolution de la maladie.
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- 2023
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19. Dynamics of polyclonal immuno-reconstitution after allogeneic transplant with post-transplant cyclophosphamide and letermovir
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Orofino, Giorgio, Xue, Elisabetta, Doglio, Matteo, Noviello, Maddalena, Tassi, Elena, Cristante, Matteo, Acerbis, Andrea, Clerici, Daniela, Farina, Francesca, Campodonico, Edoardo, Bruno, Alessandro, Piemontese, Simona, Mastaglio, Sara, Diral, Elisa, Milani, Raffaella, Ruggeri, Annalisa, Corti, Consuelo, Vago, Luca, Bonini, Chiara, Peccatori, Jacopo, Ciceri, Fabio, Lupo Stanghellini, Maria Teresa, and Greco, Raffaella
- Abstract
Cytomegalovirus (CMV) reactivations are strong stimulators of immune-reconstitution (IR) in hematopoietic stem cell transplantation (HSCT) recipients. Herein, we analyzed 317 CMV-seropositive consecutive patients (n= 109 letermovir, LTV; n= 208 no-LTV), undergoing HSCT with post-transplant cyclophosphamide (PTCy) and calcineurin inhibitor- (CNI) free graft-versus-host-disease (GvHD) prophylaxis. At day+90, median CD19+/mm3was higher in LTV-cohort: 5.5 [0;439] versus 2 [0;294], p= 0.008; median CD3+/mm3counts were lower in LTV-cohort, with no differences in CD4+, CD8+and NK-cells. At day+180 median CD3+, CD4+and CD8+/mm3values were comparable between groups. Higher CD19+/mm3counts were observed in LTV-cohort: 62 [0; 2983] versus 42 [0; 863]. Significantly higher median NK/mm3values were seen in LTV-cohort: 225.5 [0;763] versus 163.5 [0;1181], p= 0.0003. The impact of LTV on B-cell IR at 3 months and NK-cell levels at 6 months was retained in multivariate analysis (p< 0.01), whereas the effect on T-cells was not confirmed. Moreover, we confirmed a significant reduction of clinically-relevant CMV, and moderate-to- severe chronic GvHD in LTV-cohort. Overall, in our study the use of LTV was associated with a slight improvement of B-cell and NK-cells reconstitution, with only minor impact on T-cell subsets, giving new insights on polyclonal IR for HSCT recipients in the LTV era.
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- 2023
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20. Human herpesvirus 6–specific T-cell immunity in allogeneic hematopoietic stem cell transplant recipients
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Noviello, Maddalena, Lorentino, Francesca, Xue, Elisabetta, Racca, Sara, Furnari, Giulia, Valtolina, Veronica, Campodonico, Edoardo, Dvir, Roee, Lupo-Stanghellini, Maria Teresa, Giglio, Fabio, Piemontese, Simona, Clerici, Daniela, Oltolini, Chiara, Tassi, Elena, Beretta, Valeria, Farina, Francesca, Mannina, Daniele, Ardemagni, Anna, Vago, Luca, Bernardi, Massimo, Corti, Consuelo, Peccatori, Jacopo, Clementi, Massimo, Ciceri, Fabio, Bonini, Chiara, and Greco, Raffaella
- Abstract
•HHV-6 reactivation can be life-threatening for patients who are immunocompromised.•Posttransplant HHV-6–specific T cells, detectable via ELISpot assay, are significantly associated with clinically relevant infection.
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- 2023
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21. Management of Down Syndrome–Associated Leukemias: A Review
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Verma, Anupam, Lupo, Philip J., Shah, Nirali N., Hitzler, Johann, and Rabin, Karen R.
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IMPORTANCE: Down syndrome (DS), caused by an extra copy of material from chromosome 21, is one of the most common genetic conditions. The increased risk of acute leukemia in DS (DS-AL) has been recognized for decades, consisting of an approximately 150-fold higher risk of acute myeloid leukemia (AML) before age 4 years, and a 10- to 20-fold higher risk of acute lymphoblastic leukemia (ALL), compared with children without DS. OBSERVATIONS: A recent National Institutes of Health-sponsored conference, ImpacT21, reviewed research and clinical trials in children, adolescents, and young adults (AYAs) with DS-AL and are presented herein, including presentation and treatment, clinical trial design, and ethical considerations for this unique population. Between 10% to 30% of infants with DS are diagnosed with transient abnormal myelopoiesis (TAM), which spontaneously regresses. After a latency period of up to 4 years, 20% to 30% develop myeloid leukemia associated with DS (ML-DS). Recent studies have characterized somatic mutations associated with progression from TAM to ML-DS, but predicting which patients will progress to ML-DS remains elusive. Clinical trials for DS-AL have aimed to reduce treatment-related mortality (TRM) and improve survival. Children with ML-DS have better outcomes compared with non-DS AML, but outcomes remain dismal in relapse. In contrast, patients with DS-ALL have inferior outcomes compared with those without DS, due to both higher TRM and relapse. Management of relapsed leukemia poses unique challenges owing to disease biology and increased vulnerability to toxic effects. Late effects in survivors of DS-AL are an important area in need of further study because they may demonstrate unique patterns in the setting of chronic medical conditions associated with DS. CONCLUSIONS AND RELEVANCE: Optimal management of DS-AL requires specific molecular testing, meticulous supportive care, and tailored therapy to reduce TRM while optimizing survival. There is no standard approach to treatment of relapsed disease. Future work should include identification of biomarkers predictive of toxic effects; enhanced clinical and scientific collaborations; promotion of access to novel agents through innovative clinical trial design; and dedicated studies of late effects of treatment.
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- 2023
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22. New advice on an old topic: Buffers in reversed-phase HPLC
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Lupo, Sharon and Kahler, Ty
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Silicon dioxide ,High performance liquid chromatography ,Ionization ,Mass spectrometry ,Chemistry ,Science and technology - Abstract
Buffers are commonly used in reversed-phase liquid chromatography (LC) to control the ionization state of analytes. However, the addition of buffers is much more complex than simple pH control. Complex [...]
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- 2017
23. L’Observatoire des anomalies équines : recenser les anomalies et identifier celles d’origine génétique
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Delerue, Marie, Lupo, Coralie, Marcillaud-Pitel, Christel, Sabbagh, Margot, Delerue, Marie, Lupo, Coralie, Marcillaud-Pitel, Christel, and Sabbagh, Margot
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L’Observatoire des anomalies équines, géré par l’IFCE, a pour objectif de centraliser les données concernant des anomalies détectées en élevage ou chez des équidés adultes afin, dans le futur, de déterminer si ces anomalies ont une origine génétique et, si oui, identifier le ou les gènes en cause ainsi que les schémas de transmission. Malgré les problématiques remontées par les associations d’éleveurs vis-à-vis de certaines affections (mélanomes chez les chevaux gris, lymphœdème chronique progressif chez les chevaux de trait par exemple), seuls 20 cas sont déclarés par an à l’Observatoire, depuis sa création en 2008, probablement du fait d’une faible information des vétérinaires. L’Observatoire fonctionne grâce aux remontées de terrain. Lorsqu’il est en présence d’une anomalie, le vétérinaire déclare l’anomalie en ligne : le questionnaire est disponible en parallèle sur les sites de l’IFCE et du RESPE. Il envoie également des prélèvements biologiques (sang ou éventuellement crins) au laboratoire LABÉO-Frank Duncombe à Caen. Les anomalies qui peuvent être déclarées dans cet observatoire sont très variées : maladies génétiques bien identifiées (ex : épidermolyse bulleuse jonctionnelle), malformations congénitales (ex : microphtalmie), affections chroniques pour lesquelles une origine génétique est suspectée (ex : syndrome de Wobbler), ou encore des signes cliniques chroniques ou récidivants sans cause identifiée (ex : temps de saignement augmenté). Une banque de données et d’ADN est ainsi constituée et servira ensuite aux chercheurs en génétique. Le rôle des vétérinaires est primordial pour recenser et décrire finement les anomalies observées et engranger un nombre de données suffisant. Cette coopération entre les vétérinaires et les chercheurs permettra, à l’avenir, d’apporter des solutions concrètes aux éleveurs : mise au point de tests génétiques par les laboratoires d’analyses vétérinaires, conseils en croisements.
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- 2023
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24. Bilan de la surveillance des avortements équins par le Réseau d’épidémiosurveillance en pathologie équine (RESPE)
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Lupo, Coralie, Pillon, Clément, Bruyas, Jean-François, Marcillaud-Pitel, Christel, Léon-Seck, Albertine, Lupo, Coralie, Pillon, Clément, Bruyas, Jean-François, Marcillaud-Pitel, Christel, and Léon-Seck, Albertine
- Abstract
Le Réseau d’épidémiosurveillance en pathologie équine (RESPE) surveille les avortements équins présumés infectieux depuis 2009 pour détecter précocement un cas ou un foyer, afin de rapidement mettre en place des mesures de gestion et limiter l’impact sur la santé animale et sur l’économie de la filière équine française. Quatre maladies contagieuses abortives d’intérêt collectif sont surveillées : l’artérite virale équine, les infections par l’herpèsvirus équin 1 ou 4 et la leptospirose.
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- 2023
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25. Les causes infectieuses connues et soupçonnées des avortements de la jument
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Léon-Seck, Albertine, Pillon, Clément, Lupo, Coralie, Bruyas, Jean-François, Léon-Seck, Albertine, Pillon, Clément, Lupo, Coralie, and Bruyas, Jean-François
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Les avortements chez les chevaux représentent un défi sanitaire et économique important pour l’industrie équine. Les avortements infectieux sont causés dans la plupart des cas par des infections bactériennes, suivies par des virus, des champignons et des parasites. L’HVE-1, le VAE et les agents pathogènes zoonotiques sont considérés comme la principale cause d’avortement infectieux chez les chevaux et requièrent une attention accrue pour prévenir leur propagation. De nouveaux pathogènes abortifs (comme Leptospira, Neospora caninum, Coxiella burnetii, Chlamydophila abortus, etc.) ont été confirmés chez les équidés par comparaison avec des pathogènes déjà connus pour leurs propriétés abortives chez l’Homme ou chez d’autres espèces. Malgré un nombre croissant d’autopsies et l’amélioration continue des outils de diagnostic, de gestion et de surveillance, 20 à 40 % des causes d’avortement équin restent inconnues selon les pays. Pour augmenter la probabilité d’un diagnostic définitif dans les cas d’avortement et de mortinatalité chez les chevaux, de nouvelles approches diagnostiques sont nécessaires que les outils de séquençage de dernière génération permettent d’envisager.
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- 2023
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26. Post-transplant cyclophosphamide with Sirolimus or Cyclosporine for GvHD prophylaxis in matched related and unrelated transplantation: a two-center analysis on 213 consecutive patients
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Piemontese, Simona, Lupo Stanghellini, Maria Teresa, Sora, Federica, Sica, Simona, Peccatori, Jacopo, Marcatti, Magda, Metafuni, Elisabetta, Giammarco, Sabrina, Greco, Raffaella, Bruno, Alessandro, Ciceri, Fabio, Bacigalupo, Andrea, and Chiusolo, Patrizia
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- 2024
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27. Identification of USP9Xas a leukemia susceptibility gene
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Sisoudiya, Saumya Dushyant, Mishra, Pamela, Li, He, Schraw, Jeremy M., Scheurer, Michael E., Salvi, Sejal, Doddapaneni, Harsha, Muzny, Donna, Mitchell, Danielle, Taylor, Olga, Sabo, Aniko, Lupo, Philip J., and Plon, Sharon E.
- Abstract
•We identify USP9Xas a female-specific B-cell ALL susceptibility gene associated with multiple congenital anomalies.•In sporadic pediatric B-cell ALL, USP9Xacts a tumor suppressor gene in both males and females.
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- 2023
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28. Quality of Anticoagulation With Phenprocoumon and Warfarin in Left Ventricular Assist Device Patients: A Multicenter Study
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Schlöglhofer, Thomas, Marschütz, Angelika, Combs, Pamela, Stonebraker, Corinne, Lupo, Sydney, Jeevanandam, Valluvan, Riebandt, Julia, Schima, Heinrich, Zimpfer, Daniel, and Meehan, Karen
- Abstract
Anticoagulation in left ventricular assist device (LVAD) patients is essential to prevent hemocompatibility-related adverse events (HRAEs) but is challenging due to individual variability in dose-response and the small therapeutic window. Primary outcomes were international normalized ratio (INR) time in therapeutic range (TTR) and percentage of tests in range over 1 year after the first follow-up visit (FFUV), and secondary outcomes included all-cause mortality and HRAEs risk factors among phenprocoumon and warfarin users. This retrospective, multicenter study included 179 patients (age: 57.4 ± 11.8 years; female: 23.5%; HeartMate 3/HVAD: 50.8%/49.2%) implanted at the Medical University of Vienna (n = 102 phenprocoumon) and University of Chicago (n = 77 warfarin). Phenprocoumon users had a significantly higher TTR (64.9 ± 16.1% vs. 37.7 ± 21.8%, p< 0.001). One year survival (p= 0.65) and freedom from HRAE (p= 0.54) were comparable for both drugs. A multivariate analysis associated female gender (hazard ratio [HR], 2.15; 95% confidence interval [CI], 1.12–4.11; p= 0.021), no beta blockers at FFUV (HR, 2.16; 95% CI, 1.03–4.52; p= 0.042), gastrointestinal bleeding (GIB) preimplant (HR, 3.41; 95% CI, 1.32–9.45; p= 0.018), and time between INR tests (HR, 0.85; 95% CI, 0.74–0.99; p= 0.03) with a higher risk of HRAEs. To conclude, phenprocoumon versuswarfarin users had better anticoagulation quality. Female gender, longer time between INR tests, no beta blockers at FFUV, and GIB preimplant were independent risk factors for HRAEs during LVAD support.
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- 2023
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29. ANALYZING AGENT RESPONSES.
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LUPO, KESIA
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LITERARY agents ,CHICKEN coops ,DIGITAL technology ,VIRTUAL work ,POSTAL service - Abstract
The article discusses the changes in the publishing industry and how they have affected the responses that authors receive from literary agents. With the increase in submissions and the shift to digital submissions, agents often send form rejections that provide no specific feedback. However, some agents offer personalized rejections that may include compliments and insights. Another type of rejection is a "revise and resubmit" (R&R), where agents provide substantial feedback and invite authors to revise their manuscripts. The article also mentions the importance of a call with an agent, as it allows both parties to determine if they are a good fit for each other. The author concludes by sharing a personal anecdote about receiving a rejection followed by an invitation for a meeting with her agent. [Extracted from the article]
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- 2025
30. Cardiovascular risk factors and metabolic syndrome in patients treated with long-acting injectables antipsychotics: a retrospective study
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De Carlo, Vera, Grancini, Benedetta, Cassina, Niccolò, Casati, Lorenzo, Piccoli, Eleonora, Vismara, Matteo, Gobbo, Dario, Zanaschi, Raffaella, Lupo, Susanna, Olivieri, Silvia, and Dell’Osso, Bernardo
- Abstract
The present cross-sectional, retrospective study aimed to assess the prevalence of cardiovascular disease (CVD) risk factors and metabolic syndrome in a sample of psychiatric patients treated with long-acting injectable antipsychotics (LAIs). The clinical charts of 120 patients, mainly diagnosed with schizophrenia (30.0%), schizoaffective disorder (15.0%), and bipolar disorder (13.3%) on LAIs therapy – initiated in the period from 2013 to 2019 and lasting at least one year – were retrospectively reviewed and related socio-demographic, clinical and laboratory variables were collected. The 70.8% of patients were treated with first-generation LAIs, and the remaining 29.2% with second-generation LAIs. The overall sample showed low compliance in performing the required exams and evaluations related to CVD risk factors. The prevalence of metabolic syndrome was 30.8%, and, considering specific CVD risk factors, 55% of the total sample reported abdominal obesity, 43.3% arterial hypertension, 41.7% low HDL-cholesterol, 25.8% hypertriglyceridemia, and 20.8% fasting hyperglycemia. Lastly, 6.7% showed prolonged corrected QT (QTc) interval at the ECG. Patients treated with LAIs should be regularly monitored for metabolic changes and CVD risk factors. Metabolic changes rapidly develop after initiating an antipsychotic therapy and these often involve parameters, that can be easily recorded in an outpatient setting (e.g. abdominal obesity and hypertension).
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- 2023
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31. Integrated optical output layer for a reservoir computer based on frequency multiplexing
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Jalali, Bahram, Kitayama, Ken-ichi, Jonuzi, Tigers, Lupo, Alessandro, Soriano, Miguel C., Domenech Gomez, J. David, and Massar, Serge
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- 2023
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32. Parallel and deep reservoir computing based on frequency multiplexing
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Jalali, Bahram, Kitayama, Ken-ichi, Lupo, Alessandro, Zajnulina, Marina, and Massar, Serge
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- 2023
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33. CONNOLLY, MarcyKate. Hollow Dolls
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Sites, Sara-Jo Lupo
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Hollow Dolls (Novel) -- Connolly, Marcy Kate -- Book reviews ,Education ,Library and information science ,Publishing industry - Abstract
CONNOLLY, MarcyKate. Hollow Dolls. 288p. (Hollow Dolls). Sourcebooks. Jan. 2020. Tr $16.99. ISBN 9781492688198. Gr 4-6--Recently released from the clutches of evil Lady Aisling, best friends Simone and Sebastian are [...]
- Published
- 2019
34. ST. JOHN, Lauren. Kat Wolfe Takes the Case
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Sites, Sara-Jo Lupo
- Subjects
Kat Wolfe Takes the Case (Novel) -- St. John, Lauren -- Book reviews ,Education ,Library and information science ,Publishing industry - Abstract
ST. JOHN, Lauren. Kat Wolfe Takes the Case. 304p. (Wolfe and Lamb Mysteries: Bk. 2). Farrar.' Dec. 2019. Tr $16.99. ISBN 9780374309619. Gr 4-6--Katarina (Kat) Wolfe and her best friend, [...]
- Published
- 2019
35. Zn-clays in the Kihabe and Nxuu prospects (Aha Hills, Botswana): A XRD and TEM study
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Putzolu, Francesco, Abad, Isabel, Balassone, Giuseppina, Boni, Maria, Lupo, Francesco, and Mondillo, Nicola
- Abstract
Zinc clays are commonly found in oxidized Zn deposits and, even though they rarely represent the main target of the ore exploitation, they can be used as a proxy to restore the genetic conditions during ore-forming processes. This work sheds light on the micro- to nano-mineralogy and on the genesis of Zn-clays in the Kihabe and Nxuu prospects (located in the Aha Hills district, Northern Botswana), through an integrated XRD and TEM study of the mineralized facies occurring in the ore system. The Kihabe and Nxuu ores are hosted in a Neoproterozoic metamorphozed quartzwacke unconformably covered by the recent sedimentary rocks, also containing calcretes, of the Kalahari Group. In the analyzed samples, four distinct mineralogical facies have been recognized: (1) vanadate-calcrete facies, poor of Zn-clays; (2) low Zn-clay facies, characterized mostly by clays showing low Zn concentrations; (3) Zn-clay facies, containing proper Zn clay minerals; and (4) sulfide facies, devoid of Zn-clays. In all the facies detrital dioctahedral mica (muscovite and illite) is interstratified with smectite in the form of random (R0) to short-range ordered (R1) I/S, which locally shows significant Zn concentrations. In the sulfide facies kaolinite overgrowing onto mica packets has been detected. The low Zn-clay facies is dominated by Zn-bearing beidellite, with minor kaolinite and fraipontite. The Zn-clay facies consists mostly of a random (R0) interstratified clay between a 7 Å phase corresponding to fraipontite, and a 2:1 swelling clay component identifiable with the dioctahedral smectite, with minor sauconite.
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- 2023
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36. Highly purified cannabidiol improves stability and postural tone in adult patients with Lennox–Gastaut syndrome: A case series
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Calvello, Carmen, Fernandes, Mariana, Lupo, Clementina, Placidi, Fabio, Izzi, Francesca, Bianco, Ciro, Celeste, Maria Grazia, Mercuri, Nicola Biagio, and Liguori, Claudio
- Abstract
Lennox–Gastaut syndrome (LGS) is a severe developmental epileptic encephalopathy associated with numerous neurological signs and symptoms. Altered postural tone and the need for a caregiver‐assisted wheelchair are features characterizing patients with LGS. Highly purified cannabidiol (CBD) is a novel antiseizure medication (ASM) recommended for seizure treatment, in combination with clobazam, in patients with LGS. Adding CBD to the previous ASM treatment helps in reducing seizure frequency, specifically drop seizures, in patients with LGS in both clinical trials and real‐world studies. However, no data about drug effects on postural tone, motor activity, gait, and stability are available. In this case series, three adult patients diagnosed with LGS were treated with CBD as an add‐on. During the follow‐up, a slight improvement in seizure frequency was observed. Unexpectedly, an amelioration in postural tone and stability, measured using the validated Gross Motor Function Classification System, was also detected. Our case series suggests that CBD may help in managing patients with LGS regarding seizure control and in improving other aspects of the clinical spectrum of the disease, such as postural tone and stability. The mechanisms at the basis of this improvement may be related, other than seizure reduction, to the drug's effect on the brain locomotor centers, as demonstrated in animal model studies.
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- 2023
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37. Internuclear Ophthalmoplegia as an Isolated Symptom of Brainstem Wake-up Stroke Responsive to Intravenous Thrombolysis: Evidence from MRI
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Barbagallo, Gaetano, Caggiula, Marcella, Rizzo, Annalisa, Direnzo, Vita, Lupo, Angela, Fasano, Antonio, Greco, Cosimo Angelo, Pauciulo, Alfredo, Saponaro, Antonio, Paladini, Adriana, and Barbarini, Leonardo
- Abstract
Background: Internuclear ophthalmoplegia (INO) is a disorder of eye movements caused by a lesion involving the medial longitudinal fasciculus (MLF) within the brainstem, and it is characterized by adduction impairment combined with contralateral dissociated abduction nystagmus. The frequency of acute ischemic stroke (AIS) presenting with INO as a predominant symptom is very low, and many patients suffering from this brainstem AIS are precluded from intravenous thrombolysis (IVT). Objective: To provide for the first time a magnetic resonance imaging (MRI) evidence of response to the IVT in brainstem wake-up stroke presenting with INO as an isolated symptom. Methods: Here, we described a rare case of pons AIS presenting with INO as a unique symptom of awakening. In order to differentiate an ischemic stroke from other stroke mimics, and to determine whether the patient was within the therapeutic window for IVT (wake-up stroke), brain MRI including DWI and FLAIR sequences was acquired. Results: A left paramedian pontine DWI/FLAIR mismatch was detected and the patient was considered eligible for IVT. After IVT, the patient made a full recovery with complete resolution of INO. Follow-up MRI at 1 month demonstrates the absence of ischemic lesions. Conclusion: Our case provides neuroradiological evidence of IVT efficacy in brainstem stroke, and it should prompt clinicians to rapidly perform MRI in wake-up onset INO and to just as quickly administer IVT, since INO is a functionally disabling deficit. Finally, this case demonstrates the value of MRI in diagnostic, prognostic, and therapeutic workup of posterior circulation wake-up stroke.
- Published
- 2023
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38. Historical extreme winters of Istanbul: the factors that contributed to severe winters during the 20th and 21st centuries
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Yavuz, Veli, Özdaş, Mervegül, Lupo, Anthony R., Fox, Neil I., and Deniz, Ali
- Abstract
In this study, the analysis of the extreme winters that occurred in Istanbul between the years 401-2022 was carried out. Until the 21st century, the extremely low temperatures and heavy snowfalls in the province sometimes lasted for days, sometimes for weeks, which adversely affected daily life and especially transportation. In the 21st century, snow depths measured between half a metre and 1 metre have been effective rather than low temperatures. By examining the extreme events that took place between the 18th and 21st centuries as reference, the statistics for the future occurrence of these events until 2050 and 2100 are presented. The most important factor in the occurrence of four events in only 22 years in the 21st century has been the positive trend in sea surface temperature (SST) anomalies.
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- 2023
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39. Evaluation of a large set of patients with Autoimmune Polyglandular Syndrome from a single reference centre in context of different classifications
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Gatta, E., Maltese, V., Cimino, E., Cavadini, M., Anelli, V., Di Lodovico, E., Piovani, E., Zammarchi, I., Gozzoli, G., Agosti, B., Pirola, I., Delbarba, A., Girelli, A., Buoso, C., Bambini, F., Alfieri, D., Bremi, W., Facondo, P., Lupo, R., Bezzi, F., Fredi, M., Mazzola, A. M., Gandossi, E., Saullo, M., Marini, F., Licini, M., Pezzaioli, L. C., Pini, L., Franceschini, F., Ricci, C., and Cappelli, C.
- Abstract
Purpose: To characterize patients with APS and to propose a new approach for their follow-up. Query ID="Q1" Text="Please check the given names and familynames." Methods: Monocentric observational retrospective study enrolling patients referred to the Outpatients clinic of the Units of Endocrinology, Diabetology, Gastroenterology, Rheumatology and Clinical Immunology of our Hospital for Autoimmune diseases. Results: Among 9852 patients, 1174 (11.9%) [869 (73.9%) female] were diagnosed with APS. In 254 subjects, the diagnosis was made at first clinical evaluation (Group 1), all the other patients were diagnosed with a mean latency of 11.3 ± 10.6 years (Group 2). Group 1 and 2 were comparable for age at diagnosis (35.7 ± 16.3 vs. 40.4 ± 16.6 yrs, p = .698), but different in male/female ratio (81/173 vs 226/696, p = .019). In Group 2, 50% of patients developed the syndrome within 8 years of follow-up. A significant difference was found after subdividing the first clinical manifestation into the different outpatient clinic to which they referred (8.7 ± 8.0 vs. 13.4 ± 11.6 vs. 19.8 ± 8.7 vs. 7.4 ± 8.1 for endocrine, diabetic, rheumatologic, and gastroenterological diseases, respectively, p < .001). Conclusions: We described a large series of patients affected by APS according to splitters and lumpers. We propose a flowchart tailored for each specialist outpatient clinic taking care of the patients. Finally, we recommend regular reproductive system assessment due to the non-negligible risk of developing premature ovarian failure.
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- 2023
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40. Optical Calibration of Holographic Acoustic Tweezers
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Marrara, Sonia, Ciriza, David Bronte, Magazzu, Alessandro, Caruso, Roberto, Lupo, Giuseppe, Saija, Rosalba, Foti, Antonino, Gucciardi, Pietro Giuseppe, Mandanici, Andrea, Marago, Onofrio Maria, and Donato, Maria Grazia
- Abstract
Recently, acoustic tweezers based on an array of ultrasonic transducers have been reported taking inspiration from holographic optical tweezers. In the latter technique, the calibration of the optical trap is an essential procedure to obtain the trap stiffnesses. On the contrary, in the case of acoustic tweezers the calibration of the acoustic forces is seldom carried out. To cover this gap, in this work, we adapt the calibration protocols employed in optical tweezers to acoustic tweezers based on arrays of ultrasonic transducers. We measure trap stiffnesses in the mN/m range that are consistent with theoretical estimates obtained by calculations of the acoustic radiation forces based on the Gor’kov potential. This work gives a common framework to the optical and acoustic manipulation communities, paving the way to a consistent calibration of hybrid acoustooptical setups.
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- 2023
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41. Parliamentary Studies Between Sectionalism and Universalism
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Lupo, Nicola
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- 2023
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42. New Holocene Radiocarbon Dates from the Heart of the Sangha River Interval, Southwestern Central African Republic
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Schmitt, Dave N., Lupo, Karen D., Amaye, Guy T., Ndanga, Jean-Paul, Nguerede, Lucien P., and Zana, Henri
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- 2023
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43. Innate immune cell dysfunction and systemic inflammation in children with chronic liver diseases undergoing transplantation
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Mysore, Krupa R., Kannanganat, Sunil, Schraw, Jeremy M., Lupo, Philip J., Goss, John A., Setchell, Kenneth D.R., Kheradmand, Farrah, Li, Xian C., and Shneider, Benjamin L.
- Abstract
Advanced liver diseases (ALD) can affect immune function and compromise host defense against infections. In this study, we examined the phenotypic and functional alterations in circulating monocyte and dendritic cells (DCs) in children with ALD undergoing liver transplantation (LT). Children were stratified into 2 clusters, C1 (mild) and C2 (severe), on the basis of laboratory parameters of ALD and compared with healthy pediatric controls. Children in C2 had a significant reduction in frequencies of nonclassical monocytes and myeloid DCs. Children in C2 displayed monocyte and DC dysfunction, characterized by lower human leucocyte antigen DR expression and reduced interleukin 12 production, and had an increased incidence of infections before and after LT. Children in C2 demonstrated immune dysregulation with elevations of pro- and anti-inflammatory cytokines in plasma. Alterations of innate immune cells correlated with multiple laboratory parameters of ALD, including plasma bile acids. In vitro, monocytes cultured with specific bile acids demonstrated a dose-dependent reduction in interleukin 12 production, similar to alterations in children with ALD. In conclusion, a cohort of children with ALD undergoing LT exhibited innate immune dysfunction, which may be related to the chronic elevation of serum bile acids. Identifying at-risk patients may permit personalized management pre- and post-transplant, thereby reducing the incidence of infection-related complications.
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- 2023
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44. Persistence Steenrod modules
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Lupo, Umberto, Medina-Mardones, Anibal M., and Tauzin, Guillaume
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It has long been envisioned that the strength of the barcode invariant of filtered cellular complexes could be increased using cohomology operations. Leveraging recent advances in the computation of Steenrod squares, we introduce a new family of computable invariants on mod 2 persistent cohomology termed Sqk-barcodes. We present a complete algorithmic pipeline for their computation and illustrate their real-world applicability using the space of conformations of the cyclo-octane molecule.
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- 2022
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45. Genetic Testing to Inform Epilepsy Treatment Management From an International Study of Clinical Practice
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McKnight, Dianalee, Morales, Ana, Hatchell, Kathryn E., Bristow, Sara L., Bonkowsky, Joshua L., Perry, Michael Scott, Berg, Anne T., Borlot, Felippe, Esplin, Edward D., Moretz, Chad, Angione, Katie, Ríos-Pohl, Loreto, Nussbaum, Robert L., Aradhya, Swaroop, Haldeman-Englert, Chad R., Levy, Rebecca J., Parachuri, Venu G., Lay-Son, Guillermo, de Montellano, David J. Dávila-Ortiz, Ramirez-Garcia, Miguel Angel, Benítez Alonso, Edmar O., Ziobro, Julie, Chirita-Emandi, Adela, Felix, Temis M., Kulasa-Luke, Dianne, Megarbane, Andre, Karkare, Shefali, Chagnon, Sarah L., Humberson, Jennifer B., Assaf, Melissa J., Silva, Sebastian, Zarroli, Katherine, Boyarchuk, Oksana, Nelson, Gary R., Palmquist, Rachel, Hammond, Katherine C., Hwang, Sean T., Boutlier, Susan B., Nolan, Melinda, Batley, Kaitlin Y., Chavda, Devraj, Reyes-Silva, Carlos Alberto, Miroshnikov, Oleksandr, Zuccarelli, Britton, Amlie-Wolf, Louise, Wheless, James W., Seinfeld, Syndi, Kanhangad, Manoj, Freeman, Jeremy L., Monroy-Santoyo, Susana, Rodriguez-Vazquez, Natalia, Ryan, Monique M., Machie, Michelle, Guerra, Patricio, Hassan, Muhammad Jawad, Candee, Meghan S., Bupp, Caleb P., Park, Kristen L., Muller, Eric, Lupo, Pamela, Pedersen, Robert C., Arain, Amir M., Murphy, Andrea, Schatz, Krista, Mu, Weiyi, Kalika, Paige M., Plaza, Lautaro, Kellogg, Marissa A., Lora, Evelyn G., Carson, Robert P., Svystilnyk, Victoria, Venegas, Viviana, Luke, Rebecca R., Jiang, Huiyuan, Stetsenko, Tetiana, Dueñas-Roque, Milagros M., Trasmonte, Joseph, Burke, Rebecca J., Hurst, Anna C.E., Smith, Douglas M., Massingham, Lauren J., Pisani, Laura, Costin, Carrie E., Ostrander, Betsy, Filloux, Francis M., Ananth, Amitha L., Mohamed, Ismail S., Nechai, Alla, Dao, Jasmin M., Fahey, Michael C., Aliu, Ermal, Falchek, Stephen, Press, Craig A., Treat, Lauren, Eschbach, Krista, Starks, Angela, Kammeyer, Ryan, Bear, Joshua J., Jacobson, Mona, Chernuha, Veronika, Meibos, Bailey, Wong, Kristen, Sweney, Matthew T., Espinoza, A. Chris, Van Orman, Colin B., Weinstock, Arie, Kumar, Ashutosh, Soler-Alfonso, Claudia, Nolan, Danielle A., Raza, Muhammad, Rojas Carrion, Miguel David, Chari, Geetha, Marsh, Eric D., Shiloh-Malawsky, Yael, Parikh, Sumit, Gonzalez-Giraldo, Ernesto, Fulton, Stephen, Sogawa, Yoshimi, Burns, Kaitlyn, Malets, Myroslava, Montiel Blanco, Johnny David, Habela, Christa W., Wilson, Carey A., Guzmán, Guillermo G., and Pavliuk, Mariia
- Abstract
IMPORTANCE: It is currently unknown how often and in which ways a genetic diagnosis given to a patient with epilepsy is associated with clinical management and outcomes. OBJECTIVE: To evaluate how genetic diagnoses in patients with epilepsy are associated with clinical management and outcomes. DESIGN, SETTING, AND PARTICIPANTS: This was a retrospective cross-sectional study of patients referred for multigene panel testing between March 18, 2016, and August 3, 2020, with outcomes reported between May and November 2020. The study setting included a commercial genetic testing laboratory and multicenter clinical practices. Patients with epilepsy, regardless of sociodemographic features, who received a pathogenic/likely pathogenic (P/LP) variant were included in the study. Case report forms were completed by all health care professionals. EXPOSURES: Genetic test results. MAIN OUTCOMES AND MEASURES: Clinical management changes after a genetic diagnosis (ie, 1 P/LP variant in autosomal dominant and X-linked diseases; 2 P/LP variants in autosomal recessive diseases) and subsequent patient outcomes as reported by health care professionals on case report forms. RESULTS: Among 418 patients, median (IQR) age at the time of testing was 4 (1-10) years, with an age range of 0 to 52 years, and 53.8% (n = 225) were female individuals. The mean (SD) time from a genetic test order to case report form completion was 595 (368) days (range, 27-1673 days). A genetic diagnosis was associated with changes in clinical management for 208 patients (49.8%) and usually (81.7% of the time) within 3 months of receiving the result. The most common clinical management changes were the addition of a new medication (78 [21.7%]), the initiation of medication (51 [14.2%]), the referral of a patient to a specialist (48 [13.4%]), vigilance for subclinical or extraneurological disease features (46 [12.8%]), and the cessation of a medication (42 [11.7%]). Among 167 patients with follow-up clinical information available (mean [SD] time, 584 [365] days), 125 (74.9%) reported positive outcomes, 108 (64.7%) reported reduction or elimination of seizures, 37 (22.2%) had decreases in the severity of other clinical signs, and 11 (6.6%) had reduced medication adverse effects. A few patients reported worsening of outcomes, including a decline in their condition (20 [12.0%]), increased seizure frequency (6 [3.6%]), and adverse medication effects (3 [1.8%]). No clinical management changes were reported for 178 patients (42.6%). CONCLUSIONS AND RELEVANCE: Results of this cross-sectional study suggest that genetic testing of individuals with epilepsy may be materially associated with clinical decision-making and improved patient outcomes.
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- 2022
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46. Verkehrtes Tourismusland.
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Lupo
- Published
- 2024
47. Laparoscopic Repair of an Incarcerated Left Ovary, Hemi-Uterus, and Salpinx Within A Left Inguinal Hernia
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Stewart, Shai, Dekonenko, Charlene, Lupo, Andrew M., and Oyetunji, Tolulope A.
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Inguinal hernia repair is one of the most common operations performed by pediatric surgeons. These hernias typically present as asymptomatic or symptomatic swellings in the groin, extending into the labia in girls or the scrotum in boys. Surgical repair is indicated as these hernias do not spontaneously close and carry a risk of incarceration. We report a case of an extremely rare finding at the time of laparoscopic inguinal hernia repair in a preteen girl, highlighting the variable clinical presentation of this common condition and the laparoscopic approach to repair.
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- 2023
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48. The Prephase Nursing in Levodopa Carbidopa Intestinal Gel Therapy
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Lezzi, Pierluigi, Lupo, Roberto, Lezzi, Tania, and Vitale, Elsa
- Abstract
INTRODUCTION:Parkinson disease (PD) affects approximately 1% of women and men worldwide, particularly older than 60 years. It is a multisystem and neurodegenerative disease with genetics and environmental factors that result in deficits in the production of neurotransmitters, including dopamine. The levodopa-carbidopa intestinal gel (LCIG) system delivers a continuous infusion of levodopa directly into the proximal small intestine via percutaneous endoscopic jejunostomy, largely bypassing gastric emptying and absorption problems and producing more stable plasma concentrations of levodopa, eliminating the development of motor complications (dyskinesias). The aim of this review was to summarize scientific evidence on the nursing role that, together with the multidisciplinary team, made the patient's choice in this therapeutic path (pre-LCIG phase). METHODS:A literature review was carried out, conducted on the MEDLINE databases (through PubMed), The Cochrane Library, Google Scholar, and CINAHL (through EBSCO). Relevant articles for the topic were found to identify indexed primary studies that investigated the relationship between the nurse and the patient/caregiver with PD who undertakes treatment with LCIG according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. RESULTS:Nineteen studies were included in the review. The selected studies suggested how the pre-LCIG phase of patient choice and the subsequent education and training could avoid selection errors for these therapeutic paths. CONCLUSION:Trained and specialized nursing staff who carry out an adequate pre-LCIG phase associated to the multidisciplinary team improved the choice of the patient and the start of treatment and, consequently, the quality of life of PD patients.
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- 2022
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49. Serum Levels of PCSK9 Are Increased in Patients With Active Ulcerative Colitis Representing a Potential Biomarker of Disease Activity
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Marinelli, Carla, Zingone, Fabiana, Lupo, Maria Giovanna, Marin, Raffaella, D’Incà, Renata, Gubbiotti, Alessandro, Massimi, Davide, Casadei, Cesare, Barberio, Brigida, Ferri, Nicola, and Savarino, Edoardo
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- 2022
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50. Loss of FGFR4 promotes the malignant phenotype of PDAC
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D’Agosto, Sabrina, Pezzini, Francesco, Veghini, Lisa, Delfino, Pietro, Fiorini, Claudia, Temgue Tane, Gael D., Del Curatolo, Anais, Vicentini, Caterina, Ferrari, Giorgia, Pasini, Davide, Andreani, Silvia, Lupo, Francesca, Fiorini, Elena, Lorenzon, Giulia, Lawlor, Rita T., Rusev, Borislav, Malinova, Antonia, Luchini, Claudio, Milella, Michele, Sereni, Elisabetta, Pea, Antonio, Bassi, Claudio, Bailey, Peter, Scarpa, Aldo, Bria, Emilio, and Corbo, Vincenzo
- Abstract
Transcriptomic analyses of pancreatic ductal adenocarcinoma (PDAC) have identified two major epithelial subtypes with distinct biology and clinical behaviours. Here, we aimed to clarify the role of FGFR1 and FGFR4 in the definition of aggressive PDAC phenotypes. We found that the expression of FGFR4is exclusively detected in epithelial cells, significantly elevated in the classical PDAC subtype, and associates with better outcomes. In highly aggressive basal-like/squamous PDAC, reduced FGFR4expression aligns with hypermethylation of the gene and lower levels of histone marks associated with active transcription in its regulatory regions. Conversely, FGFR1has more promiscuous expression in both normal and malignant pancreatic tissues and is strongly associated with the EMT phenotype but not with the basal-like cell lineage. Regardless of the genetic background, the increased proliferation of FGFR4-depleted PDAC cells correlates with hyperactivation of the mTORC1 pathway both in vitro and in vivo. Downregulation of FGFR4in classical cell lines invariably leads to the enrichment of basal-like/squamous gene programs and is associated with either partial or full switch of phenotype. In sum, we show that endogenous levels of FGFR4limit the malignant phenotype of PDAC cells. Finally, we propose FGFR4 as a valuable marker for the stratification of PDAC patients.
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- 2022
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