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Maize samples collected in Serbia during a period of seven years were investigated on the presence of fumonisins. Concentration of fumonisins was determined by validated direct competitive Enzyme Linked Immunosorbent Assay method. This method was in accordance with European Union requirements, therefore accredited and performed in the Serbian accredited official laboratory. Summary analysis of all obtained results revealed fumonisins contamination in 82% of the total of 291 maize samples with average contamination being 1.515 mg/kg. An increase in the percentage of contaminated samples (from 51 to 100%), as well as an increase in mean fumonisin concentration in positive samples (from 0.227 to 3.281 mg/kg) and median values in positive samples (from 0.070 to 2.140 mg/kg) was noticed during the observation period. Although in Serbia there is no regular control of fumonisins in corn for animal feeding, long-term results indicate their wide distribution in this grain. Since the data on climate elements show change in temperature and precipitation in relation to multiannual average on the territory of Serbia, further research on the effects of climate change on the development of mold, the appearance of insects and the production of toxins are necessary in order to check the resistance of currently grown hybrids in the territory of Serbia on fungal growth and fumonisins production.