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A recent report from Shanxi Medical University in the People's Republic of China highlights the development of a new antimicrobial and wound healing agent. Traditional antibiotics face challenges such as bacterial resistance and poor biocompatibility, which hinder their effectiveness. In response, researchers have synthesized Fe-doped carbon dots nanozyme (Fe-CDs) using a one-step hydrothermal method with the natural herbal medicine Eucommia ulmoides. Fe-CDs demonstrated strong antimicrobial activity, high biocompatibility, and the ability to promote wound healing. This research offers promising insights into the development of novel antimicrobial materials and tissue regeneration engineering. [Extracted from the article]

A recent study conducted by researchers at Shanxi Medical University in China has found that recombinant human proteoglycan 4 (rhPRG4) can inhibit the growth and spread of osteosarcoma, a type of bone cancer. The researchers conducted experiments on human osteosarcoma cell lines and tumor-bearing mouse models to investigate the role and mechanism of PRG4 in osteosarcoma. They found that rhPRG4 inhibited cell viability, colony formation, invasion, and migration, while promoting apoptosis in osteosarcoma cells. Additionally, the study showed that PRG4 represses the genesis and metastasis of osteosarcoma by inhibiting programmed death 1 (PD-L1) expression, and that adenovirus PRG4 enhances the effectiveness of anti-PD-L1 therapy. This research provides valuable insights into potential treatment options for osteosarcoma. [Extracted from the article]

A recent study conducted by researchers at Shanxi University in China examined the spatiotemporal characteristics of net ecosystem exchange (NEE) in the Beijing-Tianjin Sand Source Region (BTSSR) and its response to drought. The study found that the BTSSR is currently a carbon sink, with the highest carbon absorption occurring during the summer and carbon release during the winter. The research also revealed that drought has a significant impact on the NEE, with increased drought intensity transforming the BTSSR into a carbon source. The study provides valuable insights into the carbon budget of different vegetation types in the region and highlights the importance of understanding the effects of drought on the carbon cycle. [Extracted from the article]

A report from Shanxi Medical University in China discusses the potential of metal-organic framework (MOF)-based nanozymes for biomedical applications. These nanozymes mimic the functions of various enzymes and can be customized to respond to different stimuli such as pH, temperature, or biomolecules. The researchers highlight the stability, adjustability, and cost-efficiency of MOF-based nanozymes, as well as their potential in therapeutic interventions like cancer therapy and tissue regeneration. The report also explores future opportunities and challenges in this emerging field. [Extracted from the article]

Researchers from Shanxi Medical University in China have conducted a study to investigate the correlation between changes in the thickness and density of the small-bowel wall and small-bowel ischemia and necrosis (SBN) on CT imaging when small-bowel obstruction (SBO) occurs. The study analyzed 186 patients with SBO and found that six CT findings were significantly correlated with SBN, including thickening of the diseased intestinal wall with the target sign. The researchers concluded that these findings may be helpful for clinical treatment. This research has been peer-reviewed and provides valuable insights into the prediction of SBN. [Extracted from the article]

A recent study from Shanxi Medical University in China explores the use of smart cellulose-based hydrogels in biomedical applications. The study highlights the unique features of hydrogels, such as high hydrophilicity, biodegradability, and biocompatibility, that make them suitable for various medical purposes. The research discusses the fabrication techniques, performance, and biomedical applications of these hydrogels. The study was supported by various funding sources and has been peer-reviewed. For more information, readers can refer to the International Journal of Biological Macromolecules. [Extracted from the article]

A recent study conducted by researchers at Shanxi Medical University in China explores the synthesis, applications in therapeutics, and bioimaging of traditional Chinese medicine-derived carbon dots (TCM-CDs). Carbon dots are fluorescent nanoparticles with various advantageous properties, such as biocompatibility and low toxicity. The study discusses different synthesis methods for TCM-CDs, their pharmacological activities, and their potential use in medical therapy and bioimaging. The research also highlights the challenges and future directions for TCM-CD development. This study provides valuable insights into the potential medicinal value of TCM-CDs. [Extracted from the article]

For more information on this research see: Bispecific Antibody Targeting Tgf-beta and Pd-l1 for Synergistic Cancer Immunotherapy. Keywords: Shanxi; People's Republic of China; Asia; Antibodies; Bispecific Antibodies; Blood Proteins; Cancer; Drugs and Therapies; Health and Medicine; Immunoglobulins; Immunology; Immunoproteins; Immunotherapy; Oncology; Proteins EN Shanxi People's Republic of China Asia Antibodies Bispecific Antibodies Blood Proteins Cancer Drugs and Therapies Health and Medicine Immunoglobulins Immunology Immunoproteins Immunotherapy Oncology Proteins 720 720 1 09/11/23 20230914 NES 230914 2023 SEP 12 (NewsRx) -- By a News Reporter-Staff News Editor at Immunotherapy Weekly -- Researchers detail new data in Cancer. [Extracted from the article]

Keywords: Shanxi; People's Republic of China; Asia; Antibacterials; Antibiotics; Anticancer Agents; Antimicrobials; Cancer; Cancer Therapy; Drug Delivery; Drug Delivery Systems; Drugs and Therapies; Emerging Technologies; Health and Medicine; Nanoplatforms; Nanotechnology; Oncology; Protective Agents EN Shanxi People's Republic of China Asia Antibacterials Antibiotics Anticancer Agents Antimicrobials Cancer Cancer Therapy Drug Delivery Drug Delivery Systems Drugs and Therapies Emerging Technologies Health and Medicine Nanoplatforms Nanotechnology Oncology Protective Agents 488 488 1 07/10/23 20230711 NES 230711 2023 JUL 11 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- Researchers detail new data in Nanotechnology - Nanoplatforms. Compared with freesmall-molecule antibacterial medicines, CD-based drug-delivery systemshave higher antibacterial efficacies, better targeting, increasedcellular uptake and internalization efficiency, and decreased systemicside effects. [Extracted from the article]

Keywords: Shanxi; People's Republic of China; Asia; Blood Diseases and Conditions; Cardiogenic Shock; Emerging Technologies; Genetics; Health and Medicine; Heart Disorders and Diseases; Machine Learning; Sepsis; Septic Shock; Support Vector Machines; Vector Machines EN Shanxi People's Republic of China Asia Blood Diseases and Conditions Cardiogenic Shock Emerging Technologies Genetics Health and Medicine Heart Disorders and Diseases Machine Learning Sepsis Septic Shock Support Vector Machines Vector Machines 254 254 1 05/08/23 20230508 NES 230508 2023 MAY 8 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- New research on Heart Disorders and Diseases - Cardiogenic Shock is the subject of a report. Characteristic genes associated with septic shock were identified and confirmed using a support vector machine model. [Extracted from the article]