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The article presents the first World Health Organization (WHO) paper on dengue vaccine that focuses on available evidence about the only dengue vaccine to have been registered by National Regulatory Authorities (NRA). The most common presentation is said to be sudden onset of fever with headache, retro-orbital pain and flushing of face. It suggests countries to consider introduction of dengue vaccine CYD-TDV only in geographic settings where epidemiological data indicate high burden of disease.

Objective. Systematize the experience and identify challenges and lessons learned in the implementation of an initiative for integrated serosurveillance of communicable diseases using a multiplex bead assay in countries of the Americas. Methods. Documents produced in the initiative were compiled and reviewed. These included concept notes, internal working papers, regional meetings reports, and survey protocols from the three participating countries (Mexico, Paraguay, and Brazil) and two additional countries (Guyana and Guatemala) where serology for several communicable diseases was included in neglected tropical diseases surveys. Information was extracted and summarized to describe the experience and the most relevant challenges and lessons learned. Results. Implementing integrated serosurveys requires interprogrammatic and interdisciplinary work teams for the design of survey protocols to respond to key programmatic questions aligned to the needs of the countries. Valid laboratory results are critical and rely on the standardized installment and roll-out of laboratory techniques. Field teams require adequate training and supervision to properly implement survey procedures. The analysis and interpretation of serosurveys results should be antigen-specific, contextualizing the responses for each disease, and triangulated with programmatic and epidemiological data for making decisions tailored to specific population socioeconomic and ecologic contexts. Conclusions. Integrated serosurveillance as a complementary tool for functional epidemiological surveillance systems is feasible to use and key components should be considered: political engagement, technical engagement, and integrated planning. Aspects such as designing the protocol, selecting target populations and diseases, laboratory capacities, anticipating the capacities to analyze and interpret complex data, and how to use it are key. [ABSTRACT FROM AUTHOR]

Brucellosis, Diseases and Conditions, Health and Medicine, Gram-Negative Bacterial Infections Keywords: Brucellosis; Diseases and Conditions; Gram-Negative Bacterial Infections; Health and Medicine EN Brucellosis Diseases and Conditions Gram-Negative Bacterial Infections Health and Medicine 1717 1717 1 05/29/23 20230602 NES 230602 2023 JUN 2 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- Investigators publish new report on brucellosis. [Extracted from the article]

Abstract: This paper considers the construction of generalized neighbor designs in circular blocks for several cases, which are useful in Serology. The initial blocks for the proposed designs are developed by using the method of cyclic shifts. Generalized neighbor designs are also constructed in linear blocks for even. Catalogs of circular binary blocks generalized neighbor designs are compiled for all cases. [Copyright &y& Elsevier]

Abstract: In this paper, we construct some new series of generalized neighbor designs. These series of designs are obtained by developing the initial blocks obtained by the Rees principle. [Copyright &y& Elsevier]

Keywords: Borrelia; Borreliosis; Clinical Research; Clinical Trials and Studies; Diagnostics and Screening; Gram-Negative Bacteria; Health and Medicine; Spirochaetaceae; Spirochaetales EN Borrelia Borreliosis Clinical Research Clinical Trials and Studies Diagnostics and Screening Gram-Negative Bacteria Health and Medicine Spirochaetaceae Spirochaetales 1113 1113 1 05/22/23 20230523 NES 230523 2023 MAY 22 (NewsRx) -- By a News Reporter-Staff News Editor at Clinical Trials Week -- Fresh data on borrelia are presented in a new report. According to the news editors, the research concluded: "Serological testing is unable to define the subgroup of patients with persistent symptoms attributed to Lyme borreliosis. [Extracted from the article]

Keywords: Adenovirus; Animal Diseases and Conditions; Antibodies; Asymptomatic Infection; Bat Coronavirus; Blood Proteins; COVID-19; Coronaviridae; Coronavirus; DNA Viruses; Epidemiology; Genetics; Herd Immunity; Hospitals; Immunoglobulins; Immunology; Nidovirales; Proteins; Public Health; RNA Viruses; Risk and Prevention; SARS-CoV-2; Severe Acute Respiratory Syndrome Coronavirus 2; Viral; Virology; Zoonosis; Zoonotic EN Adenovirus Animal Diseases and Conditions Antibodies Asymptomatic Infection Bat Coronavirus Blood Proteins COVID-19 Coronaviridae Coronavirus DNA Viruses Epidemiology Genetics Herd Immunity Hospitals Immunoglobulins Immunology Nidovirales Proteins Public Health RNA Viruses Risk and Prevention SARS-CoV-2 Severe Acute Respiratory Syndrome Coronavirus 2 Viral Virology Zoonosis Zoonotic 2023 FEB 12 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx COVID-19 Weekly -- Research findings on COVID-19 are discussed in a new report. In this article, we review four types of contemporary COVID-19 vaccines, comparing their antibody profiles and cellular aspects involved in coronavirus immunology across several population studies.". [Extracted from the article]

The article discusses the impact of the ban by the Indian government of the use of serological test kits tuberculosis (TB) diagnosis on the market. Abu Hasem Khan Choudhuy, union minister of state for health, says that private medical practitioners depend on the serological tests for diagnosis of TB despite the ban. It mentions that since July 2012, SRL Diagnostics has stopped offering TB serology assays, but small laboratories has continued to use them.

The article focuses on the study of Jae Hung Jung, MD, of Yonsei University Wonju College of Medicine in Wonju, Korea, and colleagues on the relationship between benign prostatic hyperplasia and obesity. The study was conducted amnong 571 males who undergone PSA measurement and transrectal ultrasonography. The results of the study show that increased abdominal obesity and serum leptin levels are associated with increased prostate volume.