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Multiple myeloma is a bone marrow-based plasma cell tumour that develops from asymptomatic pre-cursor conditions smouldering myeloma and monoclonal gammopathy of uncertain significance and all are characterised by the presence of a monoclonal protein in the blood. Diagnosis and distinction between these conditions is based on blood tests, the bone marrow biopsy and cross sectional imaging. There are various risk stratification models that group patients with smouldering myeloma into risk groups based on risk of progression to symptomatic disease. Management is mainly observational for patients with smouldering myeloma although clinical trials for high-risk disease may be available. Restaging is required if evidence for progression., (© 2024 British Society for Haematology and John Wiley & Sons Ltd.)

Significant efforts have been made over the past decade to facilitate the recognition of environmentally friendly packaging and promote sustainability. Yet, consumers remain confused by the excess of labels and claims used to communicate sustainability. In our previous work, we modified the appearance of recycled fibre‐based packaging by incorporating visible particles of fibre‐based waste. This strategy enabled consumers to better identify packages with a high recyclability level, enhancing their environmental perception towards sustainable products. However, the incorporation of such large waste particles proved to be detrimental to the mechanical properties of the paperboards. In this study, we further investigate the influence of the physicochemical properties of the added fibre‐based waste on packaging performance. Using a similar strategy to enhance the environmental perception, we herein studied the effect of mixed office waste (MOW), old magazines (OMG), and polylactic acid (PLA) paper cups. The presence of hydrophobic and difficult‐to‐process and difficult‐to‐disperse waste, such as the PLA paper cups, significantly altered the mechanical performance of the paperboards, whereas more hydrophilic and easy‐to‐disintegrate waste (MOW and OMG) had a lesser effect regardless of the size of the particles. Strength agents such as cationic starch (CS) and cellulose microfibrils (CMFs) successfully restored the properties of the paperboards containing MOW and OMG but were less effective for PLA paper cups. A multi‐ply strategy overcame the limitations of CS and CMFs using the redesigned paperboard as an outer ply for aesthetic purposes and a 100% recycled inner ply for restoring strength. [ABSTRACT FROM AUTHOR]

Paper and paper board are an ideal choice of packaging material due to their biodegradability. They are safer than commonly used plastic packaging materials. But due to the presence of carbon sources like cellulose and starch in paper, various pathogenic and non‐pathogenic microbes can grow well in them. The migration of microorganisms or their spores from paper to food may cause serious health hazards. Taking consumer concerns into picture, the regulatory authorities should come up for food packaging standards with regard to microbial limits of paper used in food packaging. This study pinpoints the correct approach, that is, the disintegration method in comparison to direct plating in evaluating the microbial load of 14 different samples of paper by demonstrating the limitations of methods that were eliminated. The samples were also tested for storage effect on microbial load and found to have significant reduction in bacterial load during storage at 4°C, but for fungi, it remained nearly unchanged. Further identification of predominating microbes was performed, and conclusions have been drawn on the presence of harmful and harmless species in the samples of paper. It was found that all the identified fungi are mycotoxin producing and may lead to illness of the consumer. Unlike fungi, dominating bacterial strains were found to be non‐harmful for food packaging purposes and ultimately for human use. Overall, there is an immediate need to set microbial limit standards in food packaging paper and paperboard in order to supply safe and hygiene food to consumers. [ABSTRACT FROM AUTHOR]

Chicken meat is well known for its high nutritional value. Its shelf life is short, due to the pronounced perishability, even under refrigeration. Paper bags are usually used as packaging materials, due to their biodegradability. The main negative aspect concerning paper is its high porosity and low moisture barrier. In this regard, it has to be coated/modified with efficient moisture barrier materials. The storage of chicken breast meat wrapped in four types of paper‐based materials currently in use in Romania (RO), Italy (IT), Spain (SP) and Slovenia (SLO) is reported. RO and IT are paper coated with polyethylene (PE) film, SP is waxed paper, and SLO is paper modified with hydrophobized starch. The influence of the coating film on the organoleptical, biochemical and microbiological characteristics of the chicken breast meat stored at 4°C was the aim of the study. The mathematical modelling revealed two aspects: (1) the stability period in which the meat safe for consumption is in the range 1.92–2.18 days in the case of all paper types, and (2) cadaverine, the amine generated by protein degradation, is a less sensitive indicator of the meat alteration than microbial growth. The papers coated with PE (RO and IT samples) and with hydrophobized starch (SLO paper) were packaging materials more efficient that the waxed paper (SP sample). The polyethylene film reduced the conversion of putrescine into spermidine in a higher extent than wax. [ABSTRACT FROM AUTHOR]

Collation shrink film is often used for bundling single packages of consumer goods. Like other plastic films, this type of film is currently under social pressure. Paper could be an environmentally friendly alternative if a suitable type of paper can be applied in such a way that the requirements for manipulation and transport of the bundles are met. In this study, the use of paper for bundling bottles is experimentally investigated. The study focuses on bundles of six PET bottles of 1.5 L containing flat water and sparkling water. Suitability of a paper‐based bundling method is evaluated in terms of rigidity of the bundle and in terms of resistance to horizontal inertial forces that inevitably occur during transport. Behaviour of collation shrink film‐based bundles is taken as a minimum performance level. The study shows that various paper‐based bundling methods can technically qualify as a replacement for collation shrink film and even offer additional benefits. A particular promising concept consists of a band of paper that is stretched around the bottles. It allows lifting the bottles by grasping two caps only, and it beats shrink film regarding resistance to varying horizontal inertia forces. Further research is necessary to optimise the concept and to adopt it for a wider range of products and for industrial use. [ABSTRACT FROM AUTHOR]

Now in its 61st year, Display Week has the highest number of papers submitted for the technical symposium in its recent history. Attendees will be greeted with cutting‐edge presentations, technologies, and other signature features. [ABSTRACT FROM AUTHOR]

Through 2019, all the forms in the Registrar's Office at the University of Northwestern, St. Paul were paper based, or in some cases, fillable PDFs. Students could either print them out and bring them to the office once they were completed or come by the office to pick one up, said Registrar Andy Simpson. [ABSTRACT FROM AUTHOR]

Single use packaging is one of the major contributors to environmental issues linked to waste in the environment. Packaging materials often consist of several plastics, which, when combined, are difficult to recycle. One option to reduce these issues are packaging materials for which recycling infrastructure and end markets exist, such as paper. Use of paper in food packaging applications is limited due to poor barrier properties. Enhancing barrier properties without impacting recyclability can be achieved by thin polymeric coatings combined with vapour‐deposited aluminium. Water vapour transmission rate (WVTR) of packaging materials is often assessed at 38°C and 90% relative humidity (RH). These conditions, not experienced in the supply chain, may not be optimal for paper as they have the potential to alter the structure of paper by inducing expansion disrupting barrier. This study aims at verifying this hypothesis by evaluating the influence of temperature and RH on the measured WVTR of high barrier paper. Results show that testing such papers at 38°C and 90% RH yields WVTR approximately 10 times higher than when tested at 23°C and 85% RH. The link between this increase and the disruption of the barrier layer is demonstrated by testing samples preconditioned at 38°C and 90% RH and tested at 23°C and 85% RH, depicting an increased WVTR as well. Results suggest that integrity of barrier layer in paper was disrupted at 38°C and 90% RH, and hence, these conditions are deemed inappropriate for testing barrier performance of paper materials. [ABSTRACT FROM AUTHOR]

Active wrapping papers varied in bio-based coating materials (chitosan and carboxymethyl cellulose) and vanillin concentrations (0.5%, 1.0%, 2.0%, and 4.0% (w/v)) were prepared to study their antifungal effects and release properties. Chitosan-coated paper with 1% (w/v) vanillin gave the best inhibition against mycelial growth of mango anthracnose fungi and could inhibit its conidiospores germination. The release of vanillin from a chitosan-coated paper under different conditions of temperatures (13°C, 25°C, and 37°C), relative humidity (RH) (75%, 86%, and 96% RH), and pH values (pH 3.8, 5.2, and 6.2) was studied. Moreover, the vanillin release from the paper to mango fruit under an actual commercial storage condition (13°C, 90% RH) was also investigated. The predominant mechanism of vanillin release under low temperatures (13-25°C) and all RH studied was a Fickian diffusion, whereas the high temperature (37°C) and in all buffers varying pH showed a non-Fickian behaviour. Increasing temperature and RH enhanced in diffusion coefficient (D value) from 78.24 × 10-10 to 162.10 × 10-10 cm2/s and 42.87 × 10-10 to 59.98 × 10-10 cm2/s, respectively. Meanwhile, the increasing pH value reduced the D value from 233.87 × 10-10 to 122.74 × 10-10 cm2/s. The kinetic of vanillin release under an actual wrapping application exhibited a non-Fickian behaviour, and the D value was considerably low (approximately 65.36 × 10-12 cm2/s). The developed active wrapping paper can be great interest for food industry and is practically reasonable for postharvest mango fruits. [ABSTRACT FROM AUTHOR]

Through 2019, all the forms in the Registrar's Office at the University of Northwestern, St. Paul were paper based, or in some cases, fillable PDFs. Student could either print them out and bring them to the office once they were completed or come by the office to pick one up, said Registrar Andy Simpson. [ABSTRACT FROM AUTHOR]