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Discusses research being done on the effect of fluvoxamine on plasma concentration of etizolam. Reference to a study by Y. Suzuki and colleagues, published in the December 2004 issue of the "Therapeutic Drug Monitoring"; Number of Japanese outpatients with psychiatric disorders who received fluvoxamine; Changes observed on the plasma concentration during the coadministration of fluvoxamine with etizolam.

The article presents a case of agranulocytosis in a 49-year-old man with behavioral disorders associated with mental retardation who received clozapine for several years for aggression. The agranulocytosis-related symptoms exhibited by the patient are discussed. The cause of his death is also cited.

Presents the case of a 41-year-old man with bipolar schizoaffective disorder and mental retardation who developed neuroleptic malignant syndrome after receiving several antipsychotic drugs, including respiredone. Dosage of the psychotic drugs given to the patient; Level of creatine kinase in the patient after introducing lorazepam.

Presents a case report on topiramate and valproic acid treatment in a 15-year-old mentally retarded boy with an inversion duplication of chromosome. Adverse drug reaction of the therapy; Clinical condition of the patient; Complications of the disease which developed after the therapy.

Discusses research being done on the presence of racial disparities in the quality of care for elderly patients with psychiatric disorders in the U.S. Reference to a study by B. Virnig and colleagues, published in the February 2004 issue of the "Archives of General Psychiatry"; Data used for the assessment; Comment of the researchers on the findings.