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66 results on '"van den Donk M"'

5. Effect of early intensive multifactorial therapy compared with routine care on self-reported health status, general well-being, diabetes-specific quality of life and treatment satisfaction in screen-detected type 2 diabetes mellitus patients (ADDITION-Europe): a cluster-randomised trial

Author

van den Donk, M, Griffin, SJ, Stellato, RK, Simmons, RK, Sandbaek, A, Lauritzen, T, Khunti, K, Davies, MJ, Borch-Johnsen, K, Wareham, NJ, Rutten, GEHM, van den Donk, M, Griffin, SJ, Stellato, RK, Simmons, RK, Sandbaek, A, Lauritzen, T, Khunti, K, Davies, MJ, Borch-Johnsen, K, Wareham, NJ, and Rutten, GEHM

Abstract

AIMS/HYPOTHESIS: The study aimed to examine the effects of intensive treatment (IT) vs routine care (RC) on patient-reported outcomes after 5 years in screen-detected diabetic patients. METHODS: In a pragmatic, cluster-randomised, parallel-group trial, 343 general practices in Denmark, Cambridge and Leicester (UK) and the Netherlands were randomised to screening for type 2 diabetes mellitus plus IT of multiple risk factors in people 40-69 years without known diabetes (n = 1,678 patients) or screening plus RC (n = 1,379 patients). Practices were randomised in a 1:1 ratio according to a computer-generated list. Diabetes mellitus was diagnosed according to WHO criteria. Exclusions were: life expectancy <1 year, housebound, pregnant or lactating, or psychological or psychiatric problems. Treatment targets for IT were: HbA1c <7.0% (53 mmol/mol), BP ≤135/85 mmHg, cholesterol <5 mmol/l in the absence of a history of coronary heart disease and <4.5 mmol/l in patients with cardiovascular (CV) disease; prescription of aspirin to people taking antihypertensive medication and, in cases of CV disease or BP >120/80 mmHg, ACE inhibitors were recommended. After 2003, the treatment algorithm recommended statins to all patients with cholesterol of ≥3.5 mmol/l. Outcome measures were: health status (Euroqol 5 Dimensions [EQ-5D]) at baseline and at follow-up; and health status (36-item Short Form Health Survey [SF-36] and Euroquol Visual Analogue Scale [EQ-VAS]), well-being (12-item Short Form of the Well-Being Questionnaire), diabetes-specific quality of life (Audit of Diabetes-Dependent Quality of Life) and satisfaction with diabetes treatment (Diabetes Treatment Satisfaction Questionnaire) at follow-up. At baseline, standardised self-report questionnaires were used to collect information. Questionnaires were completed at the same health assessment visit as the anthropometric and biochemical measurements. The patients and the staff assessing the outcomes were unaware of the group assi

Published
2013

8. Computerized decision support systems in primary care for type 2 diabetes patients only improve patients' outcomes when combined with feedback on performance and case management: a systematic review

Author

Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Cancer, General Practice & Nursing Science, Cleveringa, F.G.W., Gorter, K.J., van den Donk, M., Gijsel, J., Rutten, G.E.H.M., Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Cancer, General Practice & Nursing Science, Cleveringa, F.G.W., Gorter, K.J., van den Donk, M., Gijsel, J., and Rutten, G.E.H.M.

Published
2013

9. Belangrijke wijzigingen in de NHG-standaard ‘Atriumfibrilleren

Author

Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Infectieziekten, General Practice & Nursing Science, van den Donk, M., Geersing, G.J., Rutten, F.H., NHG-Werkgroep Atriumfibrilleren, x, Opstelten, W., Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Infectieziekten, General Practice & Nursing Science, van den Donk, M., Geersing, G.J., Rutten, F.H., NHG-Werkgroep Atriumfibrilleren, x, and Opstelten, W.

Published
2013

10. Intensive multifactorial treatment and cognitive functioning in screen-detected type 2 diabetes - The ADDITION-Netherlands study: A cluster-randomized trial

Author

Helmholtz Institute, Experimental Psychology (onderzoeksprogramma PF), Afd Psychologische functieleer, Leerstoel Dijkerman, Leerstoel Postma, Koekkoek, P.S., Ruis, C., van den Donk, M., Biessels, G.J., Gorter, K.J., Kappelle, L.J., Rutten, G.E.H.M., Helmholtz Institute, Experimental Psychology (onderzoeksprogramma PF), Afd Psychologische functieleer, Leerstoel Dijkerman, Leerstoel Postma, Koekkoek, P.S., Ruis, C., van den Donk, M., Biessels, G.J., Gorter, K.J., Kappelle, L.J., and Rutten, G.E.H.M.

Published
2012

11. Does early intensive multifactorial treatment reduce total cardiovascular burden in individuals with screen-detected diabetes? Findings from the ADDITION-Europe cluster-randomized trial

Author

Simmons, RK, Sharp, SJ, Sandbaek, A, Borch-Johnsen, K, Davies, MJ, Khunti, K, Lauritzen, T, Rutten, GEHM, van den Donk, M, Wareham, NJ, Griffin, SJ, Simmons, RK, Sharp, SJ, Sandbaek, A, Borch-Johnsen, K, Davies, MJ, Khunti, K, Lauritzen, T, Rutten, GEHM, van den Donk, M, Wareham, NJ, and Griffin, SJ

Abstract

AIMS: To describe the total cardiovascular burden (cardiovascular morbidity or mortality, revascularization or non-traumatic amputation) in individuals with screen-detected diabetes in the ADDITION-Europe trial and to quantify the impact of the intervention on multiple cardiovascular events over 5 years. METHODS: In a pragmatic, cluster-randomized, parallel-group trial in four centres (Denmark; Cambridge, UK; the Netherlands; and Leicester, UK), 343 general practices were randomized to screening plus routine care (n = 1379 patients), or screening and promotion of target-driven, intensive treatment of multiple risk factors (n = 1678). We estimated the effect of the intervention on multiple cardiovascular events after diagnosis of diabetes using the Wei, Lin and Weissfeld method. RESULTS: Over 5.3 years, 167 individuals had exactly one cardiovascular event, 53 exactly two events, and 18 three or more events. The incidence rates (95% CI) of first events and any event per 1000 person-years were 14.6 (12.8-16.6) and 20.4 (18.2-22.6), respectively. There were non-significant reductions in the risk of a first (hazard ratio 0.83, 95% CI 0.65-1.05) and second primary endpoint (hazard ratio 0.70, 95% CI 0.43-1.12). The overall average hazard ratio for any event was 0.77 (95% CI 0.58-1.02). CONCLUSIONS: Early intensive multifactorial treatment was not associated with a significant reduction in total cardiovascular burden at 5 years. Focusing on first events in cardiovascular disease prevention trials underestimates the total cardiovascular burden to patients and the health service.

Published
2012

12. Intensive multifactorial treatment and cognitive functioning in screen-detected type 2 diabetes - The ADDITION-Netherlands study: A cluster-randomized trial

Author

Helmholtz Institute, Experimental Psychology (onderzoeksprogramma PF), Afd Psychologische functieleer, Leerstoel Dijkerman, Leerstoel Postma, Koekkoek, P.S., Ruis, C., van den Donk, M., Biessels, G.J., Gorter, K.J., Kappelle, L.J., Rutten, G.E.H.M., Helmholtz Institute, Experimental Psychology (onderzoeksprogramma PF), Afd Psychologische functieleer, Leerstoel Dijkerman, Leerstoel Postma, Koekkoek, P.S., Ruis, C., van den Donk, M., Biessels, G.J., Gorter, K.J., Kappelle, L.J., and Rutten, G.E.H.M.

Published
2012

13. Intensive multifactorial treatment and cognitive functioning in screen-detected type 2 diabetes - The ADDITION-Netherlands study: A cluster-randomized trial

Author

Helmholtz Institute, Experimental Psychology (onderzoeksprogramma PF), Afd Psychologische functieleer, Leerstoel Dijkerman, Leerstoel Postma, Koekkoek, P.S., Ruis, C., van den Donk, M., Biessels, G.J., Gorter, K.J., Kappelle, L.J., Rutten, G.E.H.M., Helmholtz Institute, Experimental Psychology (onderzoeksprogramma PF), Afd Psychologische functieleer, Leerstoel Dijkerman, Leerstoel Postma, Koekkoek, P.S., Ruis, C., van den Donk, M., Biessels, G.J., Gorter, K.J., Kappelle, L.J., and Rutten, G.E.H.M.

Published
2012

14. Screening for Type 2 diabetes. Lessons from the ADDITION-Europe study.

Author

van den Donk, M., Sandbaek, A., Borch-Johnson, K., Lauritzen, T., Simmons, R.K., Wareham, N.J., Griffin, S.J., Davies, M.J., Khunti, K., Rutten, G.E.H.M., van den Donk, M., Sandbaek, A., Borch-Johnson, K., Lauritzen, T., Simmons, R.K., Wareham, N.J., Griffin, S.J., Davies, M.J., Khunti, K., and Rutten, G.E.H.M.

Published
2011

15. Screening for Type 2 diabetes. Lessons from the ADDITION-Europe study.

Author

van den Donk, M., Sandbaek, A., Borch-Johnson, K., Lauritzen, T., Simmons, R.K., Wareham, N.J., Griffin, S.J., Davies, M.J., Khunti, K., Rutten, G.E.H.M., van den Donk, M., Sandbaek, A., Borch-Johnson, K., Lauritzen, T., Simmons, R.K., Wareham, N.J., Griffin, S.J., Davies, M.J., Khunti, K., and Rutten, G.E.H.M.

Published
2011

16. Screening for Type 2 diabetes. Lessons from the ADDITION-Europe study.

Author

van den Donk, M., Sandbaek, A., Borch-Johnson, K., Lauritzen, T., Simmons, R.K., Wareham, N.J., Griffin, S.J., Davies, M.J., Khunti, K., Rutten, G.E.H.M., van den Donk, M., Sandbaek, A., Borch-Johnson, K., Lauritzen, T., Simmons, R.K., Wareham, N.J., Griffin, S.J., Davies, M.J., Khunti, K., and Rutten, G.E.H.M.

Published
2011

17. Screening for Type 2 diabetes. Lessons from the ADDITION-Europe study

Author

Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, van den Donk, M., Sandbaek, A., Borch-Johnson, K., Lauritzen, T., Simmons, R.K., Wareham, N.J., Griffin, S.J., Davies, M.J., Khunti, K., Rutten, G.E.H.M., Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, van den Donk, M., Sandbaek, A., Borch-Johnson, K., Lauritzen, T., Simmons, R.K., Wareham, N.J., Griffin, S.J., Davies, M.J., Khunti, K., and Rutten, G.E.H.M.

Published
2011

37. Computerized decision support, task delegation and feedback on performance in type 2 diabetes care : the diabetes care protocol

Author

Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, Rutten, Guy, Gorter, KJ, van den Donk, M., Cleveringa, F.G.W., Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, Rutten, Guy, Gorter, KJ, van den Donk, M., and Cleveringa, F.G.W.

Published
2010

38. Insulin therapy in type 2 diabetes patients : balancing between evidence and experience

Author

Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, Rutten, Guy, Gorter, KJ, van den Donk, M., van Avendonk, M.J.P., Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, Rutten, Guy, Gorter, KJ, van den Donk, M., and van Avendonk, M.J.P.

Published
2010

39. Towards a more efficient diabetes control in primary care: six-monthly monitoring compared with three-monthly monitoring in type 2 diabetes - The EFFIMODI trial. Design of a randomised controlled patient-preference equivalence trial in primary care.

Author

Brain, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Methodologie, General Practice & Nursing Science, Healthcare Innovation & Evaluation, Epidemiology & Health Economics, Wermeling, P.R., van den Donk, M., Gorter, K.J., de Wit, G.A., van der Graaf, Y., Rutten, G.E.H.M., Brain, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Methodologie, General Practice & Nursing Science, Healthcare Innovation & Evaluation, Epidemiology & Health Economics, Wermeling, P.R., van den Donk, M., Gorter, K.J., de Wit, G.A., van der Graaf, Y., and Rutten, G.E.H.M.

Published
2010

40. Cost-effectiveness of the diabetes care protocol, a multifaceted computerized decision support diabetes management intervention that reduces cardiovascular risk

Author

Brain, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Other research (not in main researchprogram), Cancer, General Practice & Nursing Science, Epidemiology & Health Economics, JC onderzoeksprogramma Methodologie, Cleveringa, F.G.W., Welsing, P.M.J., van den Donk, M., Gorter, K.J., Niessen, L.W., Rutten, G.E.H.M., Redekop, W.K., Brain, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Other research (not in main researchprogram), Cancer, General Practice & Nursing Science, Epidemiology & Health Economics, JC onderzoeksprogramma Methodologie, Cleveringa, F.G.W., Welsing, P.M.J., van den Donk, M., Gorter, K.J., Niessen, L.W., Rutten, G.E.H.M., and Redekop, W.K.

Published
2010

41. Opsporing van het metabool syndroom door mensen zelf hun middelomtrek te laten meten

Author

Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, den Engelsen, C., van den Donk, M., Gorter, K.J., Salomé, P.L., Bobbink, I.W., Rutten, G.E.H.M., Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, den Engelsen, C., van den Donk, M., Gorter, K.J., Salomé, P.L., Bobbink, I.W., and Rutten, G.E.H.M.

Published
2010

42. No negative effects of a multi-factorial, intensified treatment on self-reported health status, treatment satisfaction, and diabetes-related distress in screen-detected type 2 diabetes patients. The ADDITION-Netherlands study.

Author

Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, van den Donk, M., Gorter, K.J., Rutten, G.E.H.M., Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, General Practice & Nursing Science, van den Donk, M., Gorter, K.J., and Rutten, G.E.H.M.

Published
2010

43. Diabetes Care Protocol: effects on patient-important outcomes. A cluster randomized, non-inferiority trial in primary care

Author

Brain, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Cancer, General Practice & Nursing Science, Cleveringa, F.G.W., Minkman, M.H., Gorter, K.J., van den Donk, M., Rutten, G.E.H.M., Brain, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Cancer, General Practice & Nursing Science, Cleveringa, F.G.W., Minkman, M.H., Gorter, K.J., van den Donk, M., and Rutten, G.E.H.M.

Published
2010

50. Cognition in the early stage of type 2 diabetes

Author

Neuropsychology, psychopathology and cognition, Afd Psychologische functieleer, Ruis, C., Biessels, G.J., Gorter, K.J., van den Donk, M., Kappelle, L.J., Rutten, G.E.H.M., Neuropsychology, psychopathology and cognition, Afd Psychologische functieleer, Ruis, C., Biessels, G.J., Gorter, K.J., van den Donk, M., Kappelle, L.J., and Rutten, G.E.H.M.

Published
2009

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