1. Characteristics and Outcomes of Mycoplasma Pneumoniae Pneumonia Associated with Pulmonary Embolism and Necrotizing Pneumonia in Children
- Author
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Wang,Chenlu, Li,Lanxin, Xiao,Gang, Chen,Yuanyuan, Wang,Yingshuo, Chen,Zhimin, Zhou,Yunlian, Wang,Chenlu, Li,Lanxin, Xiao,Gang, Chen,Yuanyuan, Wang,Yingshuo, Chen,Zhimin, and Zhou,Yunlian
- Abstract
Chenlu Wang,1,2 Lanxin Li,1,2 Gang Xiao,1â 3 Yuanyuan Chen,1,2 Yingshuo Wang,1,2 Zhimin Chen,1,2 Yunlian Zhou1,2 1Department of Pulmonology, Childrenâs Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, Peopleâs Republic of China; 2National Clinical Research Center for Child Health, Hangzhou, Zhejiang, Peopleâs Republic of China; 3Department of Pediatrics, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, Peopleâs Republic of ChinaCorrespondence: Yunlian Zhou; Zhimin Chen, Department of Pulmonology, Childrenâs Hospital, Zhejiang University School of Medicine, No. 3333. Binsheng Road, Hangzhou, Zhejiang, Peopleâs Republic of China, Email zhouyunlian@zju.edu.cn; zmchen@zju.edu.cnPurpose: To explore the clinical characteristics, treatment, and long-term prognosis of mycoplasma pneumoniae pneumonia (MPP) combined with pulmonary embolism (PE) in children.Patients and Methods: The medical records of 16 children who were diagnosed with MPP associated with PE between January 2016 and January 2023 at Childrenâs Hospital, Zhejiang University School of Medicine were retrospectively reviewed.Results: The average age patients were 8.24 ± 1.99 years. All cases were diagnosed with refractory mycoplasma pneumoniae pneumonia (RMPP) and presented complications in the form of necrotizing pneumonia (NP). The main symptoms observed were cough and fever (n = 16, 100%), chest pain (n = 8, 50%), dyspnea (n = 8, 50%), and hemoptysis (n = 4, 25%). In these cases, 12 patients had involvement of the pulmonary artery, 3 patients experienced issues with the pulmonary vein, and 1 patient had simultaneous involvement of both the pulmonary artery and pulmonary vein. Among the 12 pulmonary artery embolism cases, 6 involved the right pulmonary artery, 4 involved the left pulmonary artery, and 2 involved both the right and left pulmonary arteries. The mean D-dimer level was 8.50 ± 4.76 mg/L. All patients received anticoagulant therapy, and after
- Published
- 2024