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Phytotherapy is one of the oldest medical disciplines and was traditionally based on empiricism (Reichling et al., 2008). Nowadays, its use as an additional integral component of evidence based medicine is well accepted in human medicine (Finkelmann, 2009). Herbal remedies are generally characterised by a broad therapeutic index. They consist of multicomponent mixtures and act as multi-target drugs with pleiotropic effects. In Switzerland, veterinary phytotherapy has been relaunched in 2006 as a subunit of the Swiss Medical Society for Phytotherapy (SMGP-vet). Since 2012, the certificate of qualification in veterinary phytotherapy has been approved by the Swiss Veterinary Association (GST/SVS). Historically, one of the common approaches to gain insight into the medical effects of plants was self-medication. In non-human animals, self medication remains a controversial subject, because evidence is mostly anecdotal. A few experimentally verified cases of self-medication support the theoretical expectation that animals can and do make specific foraging decisions that function specifically to remediate illness (Huffman and Caton, 2001; Villalba et al., 2006; Singer et al., 2009). In zoological medicine, this concept has first been implemented by primate keeping institutions. Permanent access to selected medicinal plants suggested self medication and helped maintain the health of certain primate species (Cousins, 2006).

Phytotherapy is one of the oldest medical disciplines and was traditionally based on empiricism (Reichling et al., 2008). Nowadays, its use as an additional integral component of evidence based medicine is well accepted in human medicine (Finkelmann, 2009). Herbal remedies are generally characterised by a broad therapeutic index. They consist of multicomponent mixtures and act as multi-target drugs with pleiotropic effects. In Switzerland, veterinary phytotherapy has been relaunched in 2006 as a subunit of the Swiss Medical Society for Phytotherapy (SMGP-vet). Since 2012, the certificate of qualification in veterinary phytotherapy has been approved by the Swiss Veterinary Association (GST/SVS). Historically, one of the common approaches to gain insight into the medical effects of plants was self-medication. In non-human animals, self medication remains a controversial subject, because evidence is mostly anecdotal. A few experimentally verified cases of self-medication support the theoretical expectation that animals can and do make specific foraging decisions that function specifically to remediate illness (Huffman and Caton, 2001; Villalba et al., 2006; Singer et al., 2009). In zoological medicine, this concept has first been implemented by primate keeping institutions. Permanent access to selected medicinal plants suggested self medication and helped maintain the health of certain primate species (Cousins, 2006).

Phytotherapy is one of the oldest medical disciplines and was traditionally based on empiricism (Reichling et al., 2008). Nowadays, its use as an additional integral component of evidence based medicine is well accepted in human medicine (Finkelmann, 2009). Herbal remedies are generally characterised by a broad therapeutic index. They consist of multicomponent mixtures and act as multi-target drugs with pleiotropic effects. In Switzerland, veterinary phytotherapy has been relaunched in 2006 as a subunit of the Swiss Medical Society for Phytotherapy (SMGP-vet). Since 2012, the certificate of qualification in veterinary phytotherapy has been approved by the Swiss Veterinary Association (GST/SVS). Historically, one of the common approaches to gain insight into the medical effects of plants was self-medication. In non-human animals, self medication remains a controversial subject, because evidence is mostly anecdotal. A few experimentally verified cases of self-medication support the theoretical expectation that animals can and do make specific foraging decisions that function specifically to remediate illness (Huffman and Caton, 2001; Villalba et al., 2006; Singer et al., 2009). In zoological medicine, this concept has first been implemented by primate keeping institutions. Permanent access to selected medicinal plants suggested self medication and helped maintain the health of certain primate species (Cousins, 2006).

Phytotherapy is one of the oldest medical disciplines and was traditionally based on empiricism (Reichling et al., 2008). Nowadays, its use as an additional integral component of evidence based medicine is well accepted in human medicine (Finkelmann, 2009). Herbal remedies are generally characterised by a broad therapeutic index. They consist of multicomponent mixtures and act as multi-target drugs with pleiotropic effects. In Switzerland, veterinary phytotherapy has been relaunched in 2006 as a subunit of the Swiss Medical Society for Phytotherapy (SMGP-vet). Since 2012, the certificate of qualification in veterinary phytotherapy has been approved by the Swiss Veterinary Association (GST/SVS). Historically, one of the common approaches to gain insight into the medical effects of plants was self-medication. In non-human animals, self medication remains a controversial subject, because evidence is mostly anecdotal. A few experimentally verified cases of self-medication support the theoretical expectation that animals can and do make specific foraging decisions that function specifically to remediate illness (Huffman and Caton, 2001; Villalba et al., 2006; Singer et al., 2009). In zoological medicine, this concept has first been implemented by primate keeping institutions. Permanent access to selected medicinal plants suggested self medication and helped maintain the health of certain primate species (Cousins, 2006).

Phytotherapy is one of the oldest medical disciplines and was traditionally based on empiricism (Reichling et al., 2008). Nowadays, its use as an additional integral component of evidence based medicine is well accepted in human medicine (Finkelmann, 2009). Herbal remedies are generally characterised by a broad therapeutic index. They consist of multicomponent mixtures and act as multi-target drugs with pleiotropic effects. In Switzerland, veterinary phytotherapy has been relaunched in 2006 as a subunit of the Swiss Medical Society for Phytotherapy (SMGP-vet). Since 2012, the certificate of qualification in veterinary phytotherapy has been approved by the Swiss Veterinary Association (GST/SVS). Historically, one of the common approaches to gain insight into the medical effects of plants was self-medication. In non-human animals, self medication remains a controversial subject, because evidence is mostly anecdotal. A few experimentally verified cases of self-medication support the theoretical expectation that animals can and do make specific foraging decisions that function specifically to remediate illness (Huffman and Caton, 2001; Villalba et al., 2006; Singer et al., 2009). In zoological medicine, this concept has first been implemented by primate keeping institutions. Permanent access to selected medicinal plants suggested self medication and helped maintain the health of certain primate species (Cousins, 2006).

Phytotherapy is one of the oldest medical disciplines and was traditionally based on empiricism (Reichling et al., 2008). Nowadays, its use as an additional integral component of evidence based medicine is well accepted in human medicine (Finkelmann, 2009). Herbal remedies are generally characterised by a broad therapeutic index. They consist of multicomponent mixtures and act as multi-target drugs with pleiotropic effects. In Switzerland, veterinary phytotherapy has been relaunched in 2006 as a subunit of the Swiss Medical Society for Phytotherapy (SMGP-vet). Since 2012, the certificate of qualification in veterinary phytotherapy has been approved by the Swiss Veterinary Association (GST/SVS). Historically, one of the common approaches to gain insight into the medical effects of plants was self-medication. In non-human animals, self medication remains a controversial subject, because evidence is mostly anecdotal. A few experimentally verified cases of self-medication support the theoretical expectation that animals can and do make specific foraging decisions that function specifically to remediate illness (Huffman and Caton, 2001; Villalba et al., 2006; Singer et al., 2009). In zoological medicine, this concept has first been implemented by primate keeping institutions. Permanent access to selected medicinal plants suggested self medication and helped maintain the health of certain primate species (Cousins, 2006).

The purpose of this study was to investigate the influence of feeding and UVB exposition on the occurrence and distribution patterns of vitamin D receptors (VDR) and calbindin D28k (Cb-D28k) in the gastrointestinal tract of veiled chameleons. Thus, 56 veiled chameleon hatchlings were divided into six treatment groups: UV (with UVB exposure); No (no supplements, no UVB exposure); CaAUV (with calcium (Ca), vitamin A supplementation, UVB exposure); CaA (with Ca, vitamin A supplementation); CaADUV (with Ca, vitamin A, vitamin D supplementation, UVB exposure); and CaAD (with Ca, vitamin A, vitamin D supplementation). Animals were reared under the suspected conditions for 6 months on locust-based diets. Tissue samples of stomach, duodenum, ileum and colon were taken, and semi-quantitative immunohistochemical methods (IHC) were performed to detect Cb-D28k and VDR. VDR immunoreactions were higher in the luminal epithelium of the duodenum than in that of the ileum. VDR immunoreactions in the luminal epithelium were higher at the base of the villi of the duodenum as compared to the tip. Cb-D28k immunoreactions were mainly observed in the luminal epithelium of the duodenum. The two groups treated with all dietary supplements (CaADUV, CaAD) exhibited a higher Cb-D28k immunoreaction as those with no supplements and UVB exposure only. No immunoreaction for both proteins could be detected in the stomach. This study suggests that the duodenum plays an important role in the active transcellular absorption of Ca in veiled chameleons as shown by the immunohistochemical detection of VDR and Cb-D28k. Expression of Cb-D28k, in particular, appears to be regulated by dietary supplementation of vitamin D and vitamin A. VDRs, however, tended to be upregulated when animals were not supplemented with Ca, vitamin D and vitamin A. This may be due to the decreased Ca concentrations which caused vitamin D activation in the skin without any supplementation, but UVB exposure.

Many case reports about different diseases in greater one-horned rhinoceroses (Rhinoceros unicornis) have been published, but an overview of the prevalence of diseases and an evaluation of causes of death is lacking. Necropsy reports of 106 greater one-horned rhinoceroses from 38 zoos worldwide were evaluated. Half of them were from adult animals, a third from perinatal deaths/stillbirths and the rest from juveniles and sub adults. Cardiac problems (cardiomyopathy, myocarditis, heart infarct) and cardiovascular failure due to gastrointestinal or pulmonary disease were the most frequent causes of death in adults. Among gastrointestinal problems, gastric ulcers and impactions, often with sand, were the most frequent findings. Sixteen adult greater one-horned rhinoceroses were euthanised, mainly due to chronic disease, foot problems or uterine leiomyomas. The two latter problems are suspected to be associated with obesity, and most of the animals with these problems were reported to be in good body condition at death. Leiomyomas are additionally thought to be predisposed by repeated oestrus cycles without pregnancy. Foot problems were only noted in 6 % of the animals and are probably underestimated in this dataset. Systematic documentation of necropsy findings is desirable, including complete animal identity, anamnesis, circumstances of death (natural death, euthanasia, and stillbirth), body condition scoring and weight.

The reference ranges of the trace elements Al, As, Be, B, Cd, Co, Cu, Fe, Mn, Mo, Ni, Pb, Li, Rb, Se, Sr, and Zn were determined by inductively coupled plasma-mass spectrometry (ICP-MS) in sera of a group of free-ranging plains viscachas of the pampa grasslands of Argentina. The values were compared with those of a small group of captive plains viscachas of the Zurich Zoo with diabetes and bilateral cataracts. In addition, a method for digestion of whole-blood samples is described for the trace element determination. Significant differences in the concentration of trace elements in the two groups of animals are discussed. No correlation was found between the levels of selenium and of other trace elements compared to the formation of cataracts