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This article presents the result of analysis of the discourse of modern social entrepreneurs as actors in the legitimation of social problems of society. Based on the ideas of a constructionist approach, we considered social problems not as an objective reality in society, but as a construct of claimsmaking to change a situation created by people. Recent studies show the low effectiveness of measures used by 'insiders' of social policy. Social entrepreneurs, being new actors in the process of advancing and legitimizing social problems, according to the authors, have high potential not only in constructing a social problem, but also in developing its effective solution. The empirical basis of the study was public speaking, interviews, and descriptions of projects presented on official websites, crowd platforms and social networks of leaders of Russian social entrepreneurship Guzel Sanzhapova (Maly Turysh village, Sverdlovsk region) and Daria Alekseeva (Charity Shop, Moscow). Both entrepreneurs are actively involved in the discourse of social problems, formulate claims-making and promote them in public arenas. In our analysis we use the concept of Peter Ibarra and John Kitsuse, which measures the discourse of social problems in four dimensions of rhetoric: Rhetorical idioms, counter-rhetoric, motifs and claims-making styles. The study showed that social entrepreneurs on the public arena do not use negative and dramatic rhetorical idioms, such as the rhetoric of endangerment, unreason and calamity. There are rhetoric of loss and rhetoric of entitlement. We conclude that social entrepreneurs play the role of 'social constructivists' (according to the Shaker Zahra typology), filling social gaps, solving acute social problems, working in those areas and with those groups that remain beyond the interests of other agents of social policy. © 2021 National Research University Higher School of Economics. All rights reserved.

The spread of COVID-19 in countries with high and medium incidence of tuberculosis has led to an increased risk of COVID-19 and tuberculosis co-infection, introducing new diagnostic and therapeutic challenges for the clinician. Hereby we describe a first case where tuberculosis and COVID-19 were diagnosed concomitantly in a Russian patient with pneumothorax. We discuss the challenges associated with the diagnosis and treatment of tuberculosis during the COVID-19 pandemic.

The spread of COVID-19 in countries with high and medium incidence of tuberculosis has led to an increased risk of COVID-19 and tuberculosis co-infection, introducing new diagnostic and therapeutic challenges for the clinician. Hereby we describe a first case where tuberculosis and COVID-19 were diagnosed concomitantly in a Russian patient with pneumothorax. We discuss the challenges associated with the diagnosis and treatment of tuberculosis during the COVID-19 pandemic.

The spread of COVID-19 in countries with high and medium incidence of tuberculosis has led to an increased risk of COVID-19 and tuberculosis co-infection, introducing new diagnostic and therapeutic challenges for the clinician. Hereby we describe a first case where tuberculosis and COVID-19 were diagnosed concomitantly in a Russian patient with pneumothorax. We discuss the challenges associated with the diagnosis and treatment of tuberculosis during the COVID-19 pandemic.

The spread of COVID-19 in countries with high and medium incidence of tuberculosis has led to an increased risk of COVID-19 and tuberculosis co-infection, introducing new diagnostic and therapeutic challenges for the clinician. Hereby we describe a first case where tuberculosis and COVID-19 were diagnosed concomitantly in a Russian patient with pneumothorax. We discuss the challenges associated with the diagnosis and treatment of tuberculosis during the COVID-19 pandemic.

The spread of COVID-19 in countries with high and medium incidence of tuberculosis has led to an increased risk of COVID-19 and tuberculosis co-infection, introducing new diagnostic and therapeutic challenges for the clinician. Hereby we describe a first case where tuberculosis and COVID-19 were diagnosed concomitantly in a Russian patient with pneumothorax. We discuss the challenges associated with the diagnosis and treatment of tuberculosis during the COVID-19 pandemic.

The article analyzes the activities of resource centers as a way of state support of socially oriented NPOs (hereinafter — SB NP Os) as providers of social services. The empirical base of the study was data from websites of non-governmental and state organizations of the Ural Federal District, 60 resource centers were analyzed. We used materials from interviews with representatives of regional SONCO (n = 16)., В статье проведен анализ деятельности ресурсных центров как способа государственной поддержки социально-ориентированных НКО (СО НКО) в качестве исполнителей социальных услуг. Эмпирическую базу исследования составили данные сайтов негосудар ственных и государственных организаций Уральского федерального округа, проанализировано 60 ресурсных центров. Использованы материалы интервью с представителями региональных СОНКО (n = 16).

The article deals with the contradictions of socially oriented activities of NGOs as service provides in two Russian regions (St. Petersburg and Sverdlovsk oblast). In the mixed system of social welfare, the importance of the non-profit sector is increasing, but the processes taking place due to the diverse regional practices are ambiguous. We focus on the issues of interaction of the non-profit sector with the state, reasons for strengthening the commercial interests of NGOs, interaction with regional authorities and the risks of the social service system at the regional level. The theoretical framework of the study is the transformation of welfare state into welfare-service state. The study used empirical data obtained by street and telephone surveys of population, interviews with representatives of NGOs, state service institutions and regional government. The analysis demonstrates that the key constraining factors for the development of NGOs as service providers are administrative barriers to access state fonds, inappropriate ways of government’s interaction with private services providers in a changing environment, the continued lack of confidence to NGO’ activities among the majority of the population. NGOs are limitedly represented in the social service provider registries for a number of reasons: high bureaucratic requirements; difficultly implemented requirements for reporting for cost recovery; strong control on NGO’s activities by the authorities; untimely informing concerning grant competitions; non-transparency of competitive procedures. The formal approach of authorities indicates that the institutional advantages of NGOs, their ability to social innovations are not considered. Overcoming the barriers for NGOs as social service providers should be also considered as a resource for increasing the public trust in private sector. © 2020 National Research University Higher School of Economics. All rights reserved.

The article presents the results of a sociological study of the motives of volunteer activities of students of schools, secondary schools (Colleges) and Universities participating in volunteer organizations implementing current social projects in Yekaterinburg. The opinion of 207 people was studied by the method of questionnaire survey, the sample population is dominated by schoolchildren, and it includes students of Colleges and undergraduate students. The analysis of the research results shows the dynamic nature of motivation of students of educational institutions to work in volunteer public organizations. The nature of the motives depends on the experience in these organizations, the degree of involvement in volunteer activities, the level of educational institutions. The predominant motives associated with the personal growth of young students, mostly cognitive motives – the desire to learn something new, learn something new, and learn new experiences. The second position is taken by the motives associated with the need to have new friends and maintain good relations with them. The third group of motives expresses the values of altruistic nature - to benefit people, to help those who need help. The authors come to the conclusion that public organizations of volunteers in educational institutions act as an external factor influencing the development of motivation for volunteering. The problem is that they should plan their activities in such a way as to meet the needs and interests of young people, to direct their activity to solve socially significant problems. Their activities should not be limited to those related to youth recreation and recreational activities., В статье представлены результаты социологического исследования мотивов волонтерской деятельности учащихся школ, средних учебных заведений (ССУЗов) и университетов (ВУЗов), участвующих в волонтерских организациях, реализующих актуальные социальные проекты в г. Екатеринбурге. Методом анкетного опроса изучено мнение 207 человек, в выборочной совокупности преобладают школьники, в нее вошли студенты ССУзов и студенты младших курсов ВУЗов. Анализ результатов исследования свидетельствует о динамичном характере мотивации учащихся образовательных учреждений к деятельности в волонтерских общественных организациях. Характер мотивов зависит от опыта работы в этих организациях, степени включенности в волонтерскую деятельность, от уровня образовательного учреждения. Преобладают мотивы, связанные с личностным ростом учащейся молодежи, в основном это познавательные мотивы – желание узнавать что-то новое, учиться чему-то новому, овладевать новым опытом. Вторую позицию занимают мотивы, связанные с потребностью иметь новых друзей и поддерживать хорошие отношения с ними. Третья группа мотивов выражает ценности альтруистического характера – приносить пользу людям, помогать тем, кто нуждается в помощи. Авторы приходят к выводу, что общественные организации волонтеров в образовательных учреждениях выступают внешним фактором, влияющим на развитие мотивации к волонтерской деятельности. Проблема состоит в том, что им необходимо планировать волонтерскую деятельность так, чтобы отвечая запросам и интересам молодежи, направлять их активность на решение общественно значимых проблем. Их деятельность не должна ограничиваться функциями, связанными с заполнением досуга молодежи и развлекательными мероприятиями.

Introduction. Volunteering is an effective tool for the development of society and a powerful personal development resource. However, ignoring the value content of volunteering in the mass organisation of volunteer youth associations reduces its ability to achieve social, economic, cultural and other altruistic goals. The formal approach to volunteering fails to meet either the public interest or the needs and expectations of young people. Participation in volunteering under the influence of external factors in case of unformed or controversial intrinsic motivation for this activity causes dissatisfaction with the work and termination of activities.Aim. On the basis of the value of volunteerism, the aim of the present publication is to identify and analyse the motivation for student volunteering.Methodology and research methods. The leading method of empirical research was the questionnaire survey among the members of volunteer organisations: schoolchildren, students of secondary specialised educational institutions and university students. The questionnaire was based on the theory of the motives of volunteering and their classification. The sample (N = 207) was formed using stratified random sampling. The quantitative research strategy included such tools as drawing up a portrait of a volunteer based on projective questions, using the method of unfinished sentences, the method of direct ranking of motives. The materials were processed in the programme Vortex 10.Results and scientific novelty. The study of the activity of volunteer associations existing on the basis of educational institutions indicates that such activity has become a compulsory type of extra-school work of students, which is veiled under volunteerism. Such “volunteering” is managed mainly through administration and is complied with the tasks of the educational institution. A typology of volunteering motives was formed, reflecting the subjective perceptions of young people. Comparison of the typolog, Введение. Волонтерская активность – действенный инструмент развития социума и мощный ресурс личностного роста. Однако игнорирование ценностной сущности волонтерства при массовой организации добровольческих молодежных объединений снижает его возможности в достижении социальных, экономических, культурных и иных альтруистических целей. Формальный подход к волонтерству не отвечает ни общественным интересам, ни потребностям и ожиданиям молодых людей. Участие в волонтерском движении под влиянием внешних факторов при несложившейся или противоречивой внутренней мотивации вызывает неудовлетворенность своей деятельностью и прекращение ее.Цель представленной в статье работы – с позиций ценностей добровольческой деятельности выявить и проанализировать мотивацию участия в ней учащейся молодежи. Методология и методы. Ведущим методом эмпирического исследования являлся анкетный опрос членов волонтерских организаций: школьников, учащихся средних специальных учебных заведений, студентов вузов. Анкета была составлена с опорой на теорию мотивов волонтерства и их классификацию. Общая совокупность респондентов (N = 207) формировалась способом стратифицированной случайной выборки. Количественная стратегия проведенной работы включала такие инструменты, как конструирование портрета волонтера на основе проективных вопросов, методы неоконченных предложений и прямого ранжирования мотивов. Собранные материалы обрабатывались в программе Vortex 10. Результаты и научная новизна. Изучение деятельности существующих на базе образовательных учреждений волонтерских объединений показало, что она превратилась в завуалированный под добровольчество обязательный вид внеучебной работы учащихся. Подобное «волонтерство» управляется в основном с помощью администрирования и подчиняется задачам учебного заведения. Сформирована типология мотивов волонтерства, отражающая субъ ективные представления молодежи. Сопоставление данной типологии с декларируемой мотивацией продемонстрировало их согласованность, но при анал, The article was prepared with the support of the Russian Science Foundation. The project No. 19–18–00246 “Challenges of the Transformation of the Welfare State in Russia: Institutional Changes, Social Investment, Digitalisation of Social Services”, which is being implemented at St. Petersburg State University., Статья подготовлена при поддержке РНФ по теме проекта № 19–18–00246 «Вызовы трансформации социального государства в России: институциональные изменения, социальное инвестирование, цифровизация социальных услуг», реализующегося в Санкт-Петербургском государственном университете.

Introduction. Volunteering is an effective tool for the development of society and a powerful personal development resource. However, ignoring the value content of volunteering in the mass organisation of volunteer youth associations reduces its ability to achieve social, economic, cultural and other altruistic goals. The formal approach to volunteering fails to meet either the public interest or the needs and expectations of young people. Participation in volunteering under the influence of external factors in case of unformed or controversial intrinsic motivation for this activity causes dissatisfaction with the work and termination of activities. Aim. On the basis of the value of volunteerism, the aim of the present publication is to identify and analyse the motivation for student volunteering. Methodology and research methods. The leading method of empirical research was the questionnaire survey among the members of volunteer organisations: schoolchildren, students of secondary specialised educational institutions and university students. The questionnaire was based on the theory of the motives of volunteering and their classification. The sample (N = 207) was formed using stratified random sampling. The quantitative research strategy included such tools as drawing up a portrait of a volunteer based on projective questions, using the method of unfinished sentences, the method of direct ranking of motives. The materials were processed in the programme Vortex 10. Results and scientific novelty. The study of the activity of volunteer associations existing on the basis of educational institutions indicates that such activity has become a compulsory type of extra-school work of students, which is veiled under volunteerism. Such “volunteering” is managed mainly through administration and is complied with the tasks of the educational institution. A typology of volunteering motives was formed, reflecting the subjective perceptions of young people. Comparison of the typo

В статье раскрываются возможности социально-проектной деятельности в медицинском учреждении как инновационного направления в решении актуальных проблем детей с тяжелыми нарушениями здоровья. С позиций социального конструирования осуществлен анализ опыта реализации социальных проектов детского медицинского центра. Представлены результаты социологических исследований, проведенных среди пациентов медицинского учреждения, что позволило обосновать преимущества практики привлечения студенческой молодежи к наставничеству над детьми-инвалидами, которое рассматривается в качестве инновационного социального проекта. Обосновывается положение о наставничестве как системе персональной поддержки в качестве ресурса личностного и социального развития детей-инвалидов, фактора их социальной интеграции., The article reveals the possibilities of social and project activities in a medical institution as an innovative direction in solving urgent problems of children with serious health problems. From the standpoint of social construction, the analysis of implementation of social projects in the children's medical center is carried out. The article presents the results of sociological research conducted among patients of medical institutions, which allowed to justify the benefi ts of the practice of attracting students to mentoring children with disabilities, which is considered as an innovative social project. The article argues for a system of mentoring as a personal support and a resource of personal and social development of children with disabilities, that is as a factor in their social integration.

The article analyzes the concept of "life strategy", identifies the features and factors of life strategies of people with disabilities. Based on the results of the empirical research carried out by the authors, a typology of life strategies of disabled people – self-realization, adaptation, survival. Each of the selected strategies is characterized by a certain combination of components of the strategy, including the ability to solve life problems, social activity, self-esteem, value orientations of people with disabilities. The predominant strategies of working and non-working disabled people are shown., В статье проанализировано понятие «жизненная стратегия», выявлены особенности и факторы формирования жизненных стратегий людей с инвалидностью. На основе результатов эмпирического исследования, проведенного авторами, предложена типология жизненных стратегий инвалидов – самореализации, приспособления, выживания. Каждая из выделенных стратегий характеризуется определенным сочетанием компонентов стратегии, среди которых способ разрешения жизненных проблем, социальная активность, самооценка, ценностные ориентации людей с инвалидностью. Показаны преобладающие стратегии работающих и неработающих инвалидов.

The comparative analysis of working and non-working people with disabilities showed that disabled people, for whom employment is a priority value of life, work, have a strong desire to be implemented in the profession, to be financially independent. Non-working disabled people prioritize the values of family, health, recognition of people around them and relatives, financial well-being. But they do not have clear ideas and plans how to implement these goals, they do not associate them with employment., Проведенный сравнительный анализ работающих и не работающих людей с инвалидностью показал, что инвалиды, для которых занятость и трудоустройство являются приоритетной жизненной ценностью, работают, имеют выраженное стремление реализоваться в профессии, быть финансово независимыми. Неработающие инвалиды в качестве приоритетных отмечают ценности семьи, здоровья, признания окружающих их людей и родных, финансовое благополучие. Но у них отсутствуют четкие представления и планы, как реализовать эти цели, они не связывают их с трудовой занятостью.

The aim of this work was an experimental and clinical study of increasing of the efficiency of therapy of respiratory tuberculosis with drug resistant pathogen by including a combination of anti-tuberculosis drugs of new generation – Bedaquiline (Bq) and Thioureidoiminomethylpyridinium perchlorate (perchlozone, Tpp) into treatment regimens. The presented results were obtained: in the experiment on a model of tuberculosis infection in 103 male C57black / 6 mice, reproduced by inserting into the lateral vein of the tail of a suspense of clinical strains of Mycobacterium tuberculosis with multi-drug resistance and with various combinations of mutations in the genes; in the clinic – on the basis of examination and treatment of 148 patients with multidrug-resistant respiratory tuberculosis. It is shown that the application of the therapy schemes for multiple and broad drug resistant tuberculosis, containing Bq and Tpp in combination with drugs, selected taking into account the drug sensitivity of mycobacteria, allows to significantly reduce the periods of relief of symptoms of intoxication, regression of inflammatory changes, abacillation and achieving positive X-ray dynamics. Undesirable phenomena against the background of combined prescription of new generation drugs, as a rule, corresponded to light and moderate severity, and in frequency of development and expression did not differ from control groups of observation., Цель настоящей работы — экспериментально-клиническое исследование возможности повышения эффективности терапии туберкулеза легких с лекарственной устойчивостью возбудителя за счет включения в схемы лечения сочетания противотуберкулезных препаратов нового поколения: бедаквилина (Bq) и тиоуреидоиминометилпиридиния перхлората (перхлозон, Tpp). Представленные результаты получены: в эксперименте — в модели туберкулезной инфекции у 103 мышей-самцов линии C57black/6, воспроизведенной путем введения в латеральную вену хвоста суспензии клинических штаммов Mycobacterium tuberculosis с множественной лекарственной устойчивостью и с различными сочетаниями мутаций в генах; в клинике — на основе обследования и лечения 148 пациентов с мультирезистентным туберкулезом органов дыхания. Показано, что применение схем терапии туберкулеза с множественной и широкой лекарственной устойчивостью возбудителя, содержащих Bq и Tpp, в комплексе с препаратами, подобранными с учетом лекарственной чувствительности микобактерий, позволяет существенно сократить сроки купирования симптомов интоксикации, регрессии воспалительных изменений, абациллирования и достижения положительной рентгенологической динамики. Нежелательные явления на фоне сочетанного назначения препаратов нового поколения, как правило, соответствовали легкой и средней тяжести, по частоте развития и выраженности не отличались от контрольных групп наблюдения.

The biosynthesis of nuclease in Serratia marcescens has been studied under the conditions of purine synthesis inhibition with 2-(p-aminobenzenesulfonamide) -thiazole. The addition of this sulfonamide to S. marcescens at different growth stages is found to inhibit both culture growth and nuclease synthesis.

The unique properties of pillared materials determine their use in catalysis, purification and separation. The paper studies the reduction of composite catalysts, Fe-pillared materials. The authors compare their reduction in low temperature capacitively coupled RF hydrogen discharge of low pressure to their conventional direct hydrogen reduction in a tubular muffle furnace. X-ray diffraction analysis was used to characterize the iron-bearing phases. The results show that the reduction of iron hydro/oxide clusters associated with an aluminosilicate matrix to metallic iron is very challenging due to the degree of the pore space availability for hydrogen.

The biosynthesis of nuclease in Serratia marcescens has been studied under the conditions of purine synthesis inhibition with 2-(p-aminobenzenesulfonamide) -thiazole. The addition of this sulfonamide to S. marcescens at different growth stages is found to inhibit both culture growth and nuclease synthesis.

© Published under licence by IOP Publishing Ltd. Aquathermolysis process is one of the key technologies of reducing the viscosity and exploitation of huge deposits of heavy crude oil. That process combines thermal and catalytical effects in the presence of water. There are a lot of types of catalysts used in aquathermolysis process, such as water and oil soluble, heterogeneous catalysts and minerals. One of the type of heterogeneous catalysts are pillared clays that used in catalytic, sorption and separation processes. Pillared clays (PILC) are the class of two-dimensional micro-mesoporous materials that have a high specific surface area, constant porosity, developed texture and active compaunds in the structure, i.e. combine both the carrier and the catalyst. In this study the physico-chemical properties of Fe-pillared clays and its application in the "reconnaissance" heavy oil catalytic aquathermolysis experiments of has been investigated.

© 2018 Elsevier B.V. Copper stearate was applied as a catalyst for the oxidation of heavy oils. The catalytic effect was investigated by high-pressure differential scanning calorimetry (HP-DSC) and accelerating rate calorimetry (ARC). The results showed that copper stearate significantly improved the oxidation performance including decreasing activation energies, enhancing combustion efficiency of coke, and reducing induction time and ignition temperature. CuO nanoparticles were in-situ formed due to the decomposition of copper stearate. To understand the catalytic mechanism, the catalytic effect of copper stearate was compared with nickel stearate, iron stearate and CuO. Furthermore, the existed form and transition of copper stearate during the oxidation process of crude oil were investigated using thermogravimetric analyser coupled with FTIR-spectrometer (TG-FTIR), HP-DSC, X-ray diffraction (XRD), scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS). The results indicated that copper stearate and in-situ formed CuO nanoparticles played their catalytic roles as a homogeneous and heterogenous catalyst in low and high-temperature ranges, respectively. It was believed that the high catalytic activity of CuO can be not only attributed to those well-known catalytic mechanisms, but also benefits from the well-distribution of both copper stearate and in-situ formed CuO nanoparticles.

This paper considers the problem organizing the formation of information competence. It's the basis of professional competence of bachelors specializing in "Mathematics and Comput-er Science", who is the future of the industry of information technology. An educational model based on the use of aggregate pedagogical approaches: integrative, differential and personality-centered, profession-oriented and competency is proposed. The mechanisms contributing to the realization of each of the pedagogical approaches applied have been pointed out. The model is based on the use of active and interactive forms and methods of training, e-learning tools. Great importance is given to the development in students of all components of information competence: knowledge, operational-activity and personality. The educational experiment conducted by the authors jointly with the students of the Institute of Mathematics and Mechanics named after N. I. Lobachevsky of Kazan Federal University, studying computer disciplines, has shown the growth in number of students with a high level of development of each of the components of information competence on the average from 3.6% to 32% and reduction in number of students with low and very low levels of development of information competence from 70.1% to 16.2%. The obtained results confirmed by the statistical criteria of hypothesis testing prove the effectiveness of the proposed pedagogical model of forming information competence of bachelors who are preparing to work in the field of information technology, by e-learning tools.

© Published under licence by IOP Publishing Ltd.The unique properties of pillared materials determine their use in catalysis, purification and separation. The paper studies the reduction of composite catalysts, Fe-pillared materials. The authors compare their reduction in low temperature capacitively coupled RF hydrogen discharge of low pressure to their conventional direct hydrogen reduction in a tubular muffle furnace. X-ray diffraction analysis was used to characterize the iron-bearing phases. The results show that the reduction of iron hydro/oxide clusters associated with an aluminosilicate matrix to metallic iron is very challenging due to the degree of the pore space availability for hydrogen.

The biosynthesis of nuclease in Serratia marcescens has been studied under the conditions of purine synthesis inhibition with 2-(p-aminobenzenesulfonamide) -thiazole. The addition of this sulfonamide to S. marcescens at different growth stages is found to inhibit both culture growth and nuclease synthesis. © 2005 Pleiades Publishing, Inc.

© Published under licence by IOP Publishing Ltd.The unique properties of pillared materials determine their use in catalysis, purification and separation. The paper studies the reduction of composite catalysts, Fe-pillared materials. The authors compare their reduction in low temperature capacitively coupled RF hydrogen discharge of low pressure to their conventional direct hydrogen reduction in a tubular muffle furnace. X-ray diffraction analysis was used to characterize the iron-bearing phases. The results show that the reduction of iron hydro/oxide clusters associated with an aluminosilicate matrix to metallic iron is very challenging due to the degree of the pore space availability for hydrogen.

This paper considers the problem organizing the formation of information competence. It's the basis of professional competence of bachelors specializing in "Mathematics and Comput-er Science", who is the future of the industry of information technology. An educational model based on the use of aggregate pedagogical approaches: integrative, differential and personality-centered, profession-oriented and competency is proposed. The mechanisms contributing to the realization of each of the pedagogical approaches applied have been pointed out. The model is based on the use of active and interactive forms and methods of training, e-learning tools. Great importance is given to the development in students of all components of information competence: knowledge, operational-activity and personality. The educational experiment conducted by the authors jointly with the students of the Institute of Mathematics and Mechanics named after N. I. Lobachevsky of Kazan Federal University, studying computer disciplines, has shown the growth in number of students with a high level of development of each of the components of information competence on the average from 3.6% to 32% and reduction in number of students with low and very low levels of development of information competence from 70.1% to 16.2%. The obtained results confirmed by the statistical criteria of hypothesis testing prove the effectiveness of the proposed pedagogical model of forming information competence of bachelors who are preparing to work in the field of information technology, by e-learning tools.

The biosynthesis of nuclease in Serratia marcescens has been studied under the conditions of purine synthesis inhibition with 2-(p-aminobenzenesulfonamide) -thiazole. The addition of this sulfonamide to S. marcescens at different growth stages is found to inhibit both culture growth and nuclease synthesis. © 2005 Pleiades Publishing, Inc.

The biosynthesis of nuclease in Serratia marcescens has been studied under the conditions of purine synthesis inhibition with 2-(p-aminobenzenesulfonamide) -thiazole. The addition of this sulfonamide to S. marcescens at different growth stages is found to inhibit both culture growth and nuclease synthesis.